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1 ine, which expresses Cre in the head surface ectoderm.
2 ndirectly suppresses Vegf3 expression in the ectoderm.
3 and they never loose contact with the neural ectoderm.
4 in the urethral endoderm and in the surface ectoderm.
5 ovement to the midline is independent of the ectoderm.
6 ventral ectoderm, but signals in the dorsal ectoderm.
7 f the p63 protein in the embryonic limbs and ectoderm.
8 ry set by the occipital lateral mesoderm and ectoderm.
9 l and anteroposterior regionalisation of the ectoderm.
10 cretory cells in the anteriormost non-neural ectoderm.
11 ntial to plasticity and pattern in the early ectoderm.
12 c absence of BMP activity in the preplacodal ectoderm.
13 blastula embryo into endoderm, mesoderm and ectoderm.
14 blast, which is derived from extra-embryonic ectoderm.
15 ression to the lateral domains of the animal ectoderm.
16 programs in the epiblast and extraembryonic ectoderm.
17 inhibitors are required for formation of the ectoderm.
18 c lateral plate mesoderm (LPM) and overlying ectoderm.
19 of the anterior-posterior and dorsal-ventral ectoderm.
20 etrads and rosettes in Fgfr2 mutant limb-bud ectoderm.
21 ivity, which is specified as the preplacodal ectoderm.
22 paration of the mesoderm, neuroectoderm, and ectoderm.
23 ary band emerge adjacent to the central oral ectoderm.
24 derm actively patterns the adjacent boundary ectoderm.
25 es of ES cell differentiation into the neuro-ectoderm.
26 es in periodic patterns is restricted to the ectoderm.
27 f the pharynx, which separates endoderm from ectoderm.
28 s to correctly locate and specify the border ectoderm.
29 o into the early epiblast and extraembryonic ectoderm.
30 l spatial organization of the embryonic oral ectoderm.
31 the neural plate and the adjacent non-neural ectoderm.
32 echanism for rostro-caudal patterning of the ectoderm.
33 ng of complex tissues such as the vertebrate ectoderm.
34 expressed with neural genes in the embryonic ectoderm.
35 rises at the border of neural and non-neural ectoderm.
36 l crest, ocular-surface ectoderm, or surface ectoderm.
37 y from the ventral midline to the neurogenic ectoderm.
38 etinal cells, lens cells, and ocular-surface ectoderm.
39 ely unknown patterning cues expressed by the ectoderm.
40 expressed throughout dorsal and ciliary band ectoderm.
41 dial contractile processes (myonemes) in the ectoderm.
42 ryos permits immunocyte insertion in ventral ectoderm.
43 n of Foxg1 expression in the anterior neural ectoderm.
44 l ectoderm and ciliary band, but not ventral ectoderm.
45 es such as endoderm, mesendoderm, and neural ectoderm.
46 will give rise both to hindgut and to border ectoderm.
47 orsal surface of the somites and contact the ectoderm.
49 h bilaterally separates the oral from aboral ectoderm; (3) the vegetal lateral CB, which bilaterally
50 ereas Univin is bilaterally expressed in the ectoderm adjacent to the anterior skeleton during the re
51 ion of neural precursor genes in the ventral ectoderm also involves both the AB region and the Eh-1 m
52 elay in expression of Fgf8 in branchial arch ectoderm and a failure of neural crest cells in the arch
53 r of the re-specified posterior-ventral oral ectoderm and by larval stages it is in the same plane ne
54 nd re-enter ectoderm, distributing in dorsal ectoderm and ciliary band, but not ventral ectoderm.
55 at maintain a proliferative, immature neural ectoderm and down-regulates genes that promote the trans
56 ct of the embryo that separate endoderm from ectoderm and ectoderm from neurogenic apical plate and t
57 e initial specification of posterior-ventral ectoderm and endoderm fates, eliminating the ventral con
58 sh foxi1 is also expressed in branchial arch ectoderm and endoderm, and morpholino knock-down of foxi
61 sue-specific functions in patterning surface ectoderm and its appendages by controlling division orie
64 a Gata2 target gene that is required in both ectoderm and mesoderm for primitive hematopoiesis to occ
70 embryos, we show that affecting Vmem of the ectoderm and no other cell layers is sufficient to cause
72 lls and allowed discrimination of non-neural ectoderm and otic lineage cells from off-target populati
74 calcifying medium between the calicoblastic ectoderm and pre-existing skeleton, separated from the o
75 t cells that arise at the interphase between ectoderm and prospective epidermis of the neurulating em
77 w lens vesicle separation from the overlying ectoderm and regulate corneal epithelial proliferation.
78 results suggest ancient roles in non-neural ectoderm and regulating specific mesenchymal-to-epitheli
79 in lamprey as the LPM is separated from the ectoderm and sequestered to the coelomic linings during
80 rns with Sost being restricted to the distal ectoderm and Sostdc1 to the proximal ectoderm and the me
85 omodeal subdomain emerges inside of the oral ectoderm, and bilateral subdomains defining the lateral
87 the ability to differentiate down mesoderm, ectoderm, and endoderm lineages, demonstrating pluripote
88 vertebrate-like arrangements in hemichordate ectoderm, and homologous genetic mechanisms regulate ect
89 he ectoplacental cone, in the extraembryonic ectoderm, and in trophoblast giant cells in the E6.5 emb
90 ion in the archenteron requires contact with ectoderm, and loss-of-function experiments indicate that
92 aggregation promoting pluripotency loss and ectoderm, and slower aggregation favoring mesoderm and e
93 arly gene expression domains in the anterior ectoderm, and that variants in KCNJ2 disrupt this region
94 cation of the immediately adjacent stripe of ectoderm, and the restriction of the apical neurogenic d
95 chyme, overlying olfactory placode/epidermal ectoderm, and underlying neuroepithelium, as well as the
96 specifies a neural fate in undifferentiated ectoderm; and (2) transformation induces posterior spina
98 patterning the neural crest and preplacodal ectoderm are specified in adjacent domains at the neural
100 pore, which are fated to become neural plate ectoderm, are polarized and have straight boundaries.
101 between the neuroepithelium and the surface ectoderm, are required for completion of neural tube clo
102 lx4b, which are expressed in the preplacodal ectoderm, are required for the expression of a cell-auto
104 dy segments, but pattern elements in lateral ectoderm arise via distinct cell lineages in the segment
105 il their expression is cleared from the oral ectoderm as an indirect consequence of Nodal signaling.
106 uish differentiated neurons from nonneuronal ectoderm as it does in many other animals, but instead c
108 erived ectoplacental cone and extraembryonic ectoderm, as well as in the yolk sac and labyrinth tissu
109 regional expression in ventrolateral surface ectoderm at E10.5, much earlier than previously reported
111 After induction and specification in the ectoderm, at the border of the neural plate, the neural
114 ferent boundaries: repulsion at the mesoderm-ectoderm border, decreased adhesion at the notochord-pre
115 murfs regulate tissue separation at mesoderm/ectoderm boundaries through antagonistic interactions wi
116 iated band cells and cells from the endoderm/ectoderm boundary that will give rise both to hindgut an
117 ells begin to exit the neural fold/epidermal ectoderm boundary, we examined the cranial mesenchyme, c
118 ch are specific to vertebrates, arise in the ectoderm but can generate cell types that are typically
121 a star embryo initially has a pan-neurogenic ectoderm, but the genetic mechanism that directs a subse
123 replacodal competence throughout the ventral ectoderm by coinducing Tfap2a, Tfap2c, Foxi1 and Gata3.
124 transcription factor that expands the neural ectoderm by down-regulating genes that promote the onset
125 ivated in the ventral midline and neurogenic ectoderm by the Spitz ligand, which is processed by the
128 eport that in response to FGF the non-neural ectoderm can ectopically express several early neural cr
129 These results suggest that the non-neural ectoderm can launch the neural crest program in the abse
130 rmore, in vivo Fgfr2 loss-of-function in the ectoderm caused derepression of Shh, revealing a role fo
131 single cilia are transiently present on each ectoderm cell of the late neurula/early tailbud stage em
133 ype of adhesive contact between mesoderm and ectoderm cells that shows properties of a cleft-like bou
135 t the blastopore and ectopic constriction of ectoderm cells triggered by the actin-binding protein Sh
136 en up from the body cavity into the PMCs and ectoderm cells, where the two labels are predominantly c
137 cells from the stomodeal region of the oral ectoderm, ciliated band cells and cells from the endoder
138 migrate, either surrounding the prospective ectoderm contributing to the embryo proper, or into the
139 work explains how spatial patterning in the ectoderm controls progression of neurogenesis in additio
140 Edn1 expression is limited to the overlying ectoderm, core paraxial mesoderm and pharyngeal pouch en
142 e a dynamic expression pattern of Shh in the ectoderm covering the frontonasal (FNP) and maxillary (M
143 or endoderm, and that FGF signaling from the ectoderm defines the location and amount of mesoderm.
144 but its specification of ventral neurogenic ectoderm demands a relatively high-threshold response to
146 our results illustrate an integral role for ectoderm-derived Edn1 in early arch morphogenesis, parti
147 lymphoid blood cells and other mesoderm- and ectoderm-derived tissues retained UPD of the entire mate
148 erning to develop into several endoderm- and ectoderm-derived tissues, mimicking their in vivo counte
150 ific deletion of the PRC2 proteins embryonic ectoderm development (EED) (a subunit required for PRC2
151 ed via combinatorial regulation of embryonic ectoderm development (EED) and lysine-specific demethyla
153 var)3-9; E(z); Trithorax] (SET)-7, embryonic ectoderm development (EED), and SU(Z)12 (suppressor of z
154 olycomb group (PcG) proteins CBX7, embryonic ectoderm development (EED), enhancer of zeste homologue
155 which the essential PRC2 subunits embryonic ectoderm development (EED), suppressor of zeste 12 homol
156 ains are suppressed by mutation of embryonic ectoderm development or Su-(var)3-9; E(z); Trithorax (se
157 e report the identification of the embryonic ectoderm development polycomb histone-methylation modula
158 erlap those following knockdown of embryonic ectoderm development, a common cofactor of EZH2 and EZH1
162 pregnant mutant females revealed defects in ectoderm differentiation leading to abnormal foetal deve
163 we showed that Wnt ligands from the surface ectoderm directly or indirectly elicit a Wnt/beta-cateni
164 nsition to mesenchyme, migrate, and re-enter ectoderm, distributing in dorsal ectoderm and ciliary ba
165 ssion of the Nodal ligand in the future oral ectoderm during cleavage, a sequence of regulatory gene
169 ic lineage commitment during gastrulation to ectoderm (early switch) or mesoderm/endoderm (late switc
170 sential roles of Htt in the specification of ectoderm, endoderm and mesoderm, in the specification of
171 axial and paraxial mesoderm, lateral plate, ectoderm, endoderm) to drive axis morphogenesis remain l
172 e sea urchin, a prototypic deuterostome, the ectoderm-endoderm boundary is established before gastrul
174 epithelial cyst with an asymmetric amniotic ectoderm-epiblast pattern that resembles the human amnio
177 in early head development and pituitary oral ectoderm exhibit craniofacial defects and pituitary glan
178 for Otx2 deficiency in the pituitary neural ectoderm exhibited altered patterning of gene expression
183 ially synchronous guidance toward non-neural ectoderm, followed by comparatively asynchronous occurre
184 nent analysis on the transcriptomes of these ectoderm fragments primarily identifies embryonic axes a
186 ryo that separate endoderm from ectoderm and ectoderm from neurogenic apical plate and that delineate
188 gion between the neural plate and non-neural ectoderm from which multiple cell types, including lens
191 signal activates a unique subcircuit of the ectoderm gene regulatory network, including the transcri
193 ch selectively prevent transcription of oral ectoderm genes until their expression is cleared from th
194 not gene product acts to repress other oral ectoderm genes, contributing crucially to the bilateral
195 permitted construction of an enhanced animal ectoderm GRN model highlighting the repressive interacti
197 Rather, modulation of Pvr levels in the ectoderm has an impact on PIP3 membrane accumulation, co
198 tivation of the RAF signaling pathway in the ectoderm has effects on specific steps of epidermal diff
199 s (PMCs) and the overlying pattern-dictating ectoderm; however, our understanding of the molecular ba
200 t (NC), cranial placode (CP), and non-neural ectoderm in multiple hPSC lines, on different substrates
203 ere first recruited to the dorsal non-neural ectoderm in the tunicate-vertebrate ancestor but subsequ
207 trulation and progressively divide embryonic ectoderm into neural and non-neural regions, followed by
208 tivation of the same enhancers in the dorsal ectoderm is associated with Polycomb-repressed H3K27me3
210 onstrates that Otx2 expression in the neural ectoderm is important intrinsically for the development
211 During vertebrate neurulation, the embryonic ectoderm is patterned into lineage progenitors for neura
212 n the centipede, vsx expressing invaginating ectoderm is situated bilaterally adjacent to the medial
213 in mesoderm, or ectopic Snail expression in ectoderm, is sufficient to drive early disassembly of ju
214 tive of lineage, spanning the ocular surface ectoderm, lens, neuro-retina, and retinal pigment epithe
218 e prevents the ectopic expression of lateral ectoderm markers, independently of its role in neural sp
219 B markers, which are co-expressed in lateral ectoderm, medial neural plate or posterior-lateral mesod
222 astrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while
224 nuates planar cell polarity signaling at the ectoderm-mesoderm boundary to lower cell adhesion and fa
225 the border of the neural plate and epidermal ectoderm, migrate extensively and differentiate into div
226 neurons originate in placodes in the surface ectoderm, migrating to form ganglia that connect to the
227 bserved in the adherens junctions in Xenopus ectoderm, mouse embryonic, and epiblast stem cells.
228 ad-like 2 (GRHL2) is expressed in non-neural ectoderm (NNE) and Grhl2 loss results in fully penetrant
230 tic sac-with the embryonic disc and amniotic ectoderm occupying opposite poles-is a vital milestone d
235 ting potential) regionalization found in the ectoderm of neurulating embryos, and changes the normal
238 tingly, despite strong expression of Vax1 in ectoderm of the medial nasal processes, the upper lip re
240 self-organization of all three germ layers: ectoderm on the outside layer, mesoderm in the middle an
241 derm segmentation is either dependent on the ectoderm, or occurs through an independent mechanism.
243 sets of transcription factors subdivides the ectoderm over time into smaller domains of progenitors f
244 expression of an FGF ligand, fgf8/17/18, in ectoderm overlying sites of mesoderm specification withi
248 Ciona intestinalis exhibits a proto-placodal ectoderm (PPE) that requires inhibition of bone morphoge
250 hat represent the mouse embryonic non-neural ectoderm, preplacodal ectoderm and otic vesicle epitheli
251 cal expression of marker genes of non-neural ectoderm, preplacodal ectoderm, and early otic lineage.
255 regulatory genes that contribute to the oral ectoderm regulatory state during specification in Strong
256 Wnt11r and Wnt4a from the head mesoderm and ectoderm, respectively, play distinct roles in the segme
258 code to define positional information of any ectoderm sample along the anterior-posterior and dorsal-
260 pigenomes of cell types derived from surface ectoderm (SE), including keratinocytes and breast lumina
261 strular sea urchin embryo surrounds the oral ectoderm, separating it from adjacent embryonic territor
262 ting cultures first expressed the non-neural ectoderm specific transcriptional factors TFAP2A, GATA2,
264 ier work to be an essential mediator of oral ectoderm specification in the sea urchin embryo, and ind
269 ctive event of the mesoderm on the overlying ectoderm that generates a neural plate that, after rolli
270 from the otic placode, a thickened swathe of ectoderm that invaginates to form the otic vesicle.
272 driven by the occipital lateral mesoderm and ectoderm, that ensure cell transport and organ assembly
273 somites, pharyngeal pouches, the preplacodal ectoderm (the common precursor region of many cranial se
276 regulatory genes in the central animal oral ectoderm thereby confining their expression to the later
277 of the embryo from invading the prospective ectoderm, thereby restricting endoderm- and mesoderm-ind
278 suppresses genes within the PMCs and in the ectoderm to impact PMC patterning and skeletogenesis.
280 from its early induction from the embryonic ectoderm to the establishment of the three cardinal axes
281 at activation of BRAF in the embryonic mouse ectoderm triggers both craniofacial and skin defects, in
282 importance of the non-neural and preplacodal ectoderm, two critical precursors during inner ear devel
283 f these neural crest markers, the non-neural ectoderm upregulates both BMP and Wnt molecules in respo
284 s that determine gap sizes and shapes in the ectoderm, using a general model of interstitial gap mech
286 rmation suggested derivation from neuralized ectoderm, via meso-ectodermal, or neural-non-neural ecto
287 inants, such as Twist, into the neural plate ectoderm was crucial to the emergence of the vertebrate
288 tain spatial information, dorsal and ventral ectoderm was subdivided along the anterior-posterior and
289 pecification of a broad neurogenic potential ectoderm was subsequently overlaid with a module for pat
290 The lack of FGF signaling from the neural ectoderm was sufficient to impair anterior lobe growth,
291 he dorsal neuroepithelium, or in the surface ectoderm, we show that these protrusions originate from
293 ligands Wnt9a and Wnt5b are expressed in the ectoderm, whereas juxtaposed chondrocytes express Frzb a
295 ectopic expression of BMP5-8 in the ventral ectoderm (which induces an O-to-P fate change in the mid
296 -mediated separation of this tissue from the ectoderm, which can be rescued by the coincident inhibit
298 corneal epithelium is descended from surface ectoderm, while the iris and collagen-rich stroma of the
299 fate by BMP5-8 emanating from the dorsalmost ectoderm, while the more ventral cell assumes the O fate
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