ライフサイエンスコーパス: ectromelia

1 poxviruses, including monkeypox, cowpox, and ectromelia.

2 ific amplicons identified and differentiated ectromelia and vaccinia virus strains, which contain a t

3 g viruses that produce ATIs, such as cowpox, ectromelia, and raccoonpox viruses, as well as those suc

4 Some orthopoxviruses, e.g., the cowpox, ectromelia, and raccoonpox viruses, form large, discrete

5 iola, vaccinia, cowpox, monkeypox, camelpox, ectromelia, and taterapox viruses.

6 cytotoxicity, may be one mechanism by which ectromelia evades the host immune response.

7 nt strains and isolates of camelpox, cowpox, ectromelia, gerbilpox, herpes, monkeypox, myxoma, rabbit

8 l determinants are immunogenic in cowpox and ectromelia (mousepox) virus infections, and immunization

9 ly cross-reactive variant peptide encoded by ectromelia (mousepox) virus.

10 uding vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), and variola viruses.

11 We demonstrate that the ectromelia poxvirus p13 protein, bearing homology to the

12 er orthopoxviruses; however, four strains of ectromelia virus (ECT) examined contained an intact crmD

13 The orthopoxviruses ectromelia virus (ECTV) and vaccinia virus (VACV) expres

14 gold standard vaccine--as the immunogen and ectromelia virus (ECTV) as the pathogen to demonstrate t

15 Ectromelia virus (ECTV) encodes an IFN-gamma-binding pro

16 tions with smallpox in humans or the related ectromelia virus (ECTV) in mice.

17 Studies of the effects of ectromelia virus (ECTV) infection on NK cells demonstrat

18 homolog of VCP is able to bind VACV A56, the ectromelia virus (ECTV) VCP homolog is only able to bind

19 hat NF-kappaB is essential for resistance to ectromelia virus (ECTV), a mouse orthopoxvirus related t

20 o highly related (>92% homology) poxviruses: ectromelia virus (ECTV), a natural mouse pathogen, and v

21 Ectromelia virus (ECTV), an orthopoxvirus that naturally

22 ecies vaccinia virus, and the mouse pathogen ectromelia virus (ECTV), form two types of infectious vi

23 The F13L ortholog in ectromelia virus (ECTV), the agent of mousepox, is EVM03

24 ll required for resistance to infection with ectromelia virus (ECTV).

25 2A is selectively required for resistance to ectromelia virus (ECTV).

26 inia virus (VACV) in protecting mice against ectromelia virus (ECTV).

27 uman smallpox virus and the mouse-equivalent ectromelia virus (ECTV; an agent of mousepox), encode im

28 s important for recovery from infection with ectromelia virus (EV), a natural murine poxvirus pathoge

29 tical determinant of viral virulence for the ectromelia virus (mousepox virus) in a murine infection

30 vaccinia virus DNA into cells infected with ectromelia virus and assaying for MAb reactivity, we map

31 resent study, we used the mouse-specific OPV ectromelia virus and mice deficient in CD40, B cells, or

32 nstrate that the p28 proteins encoded by the ectromelia virus and the variola virus possess E3 ubiqui

33 Whereas the human variola virus and mouse ectromelia virus encode one vTNFR, the broad host range

34 Mice infected with a p13 deletion mutant of ectromelia virus had elevated cytotoxicity for YAC-1 tum

35 Similar to the human pathogen variola virus, ectromelia virus has a limited host range and provides a

36 The ectromelia virus homolog of the vaccinia virus A33R gene

37 ystal structure of an orthopoxvirus IL-18BP, ectromelia virus IL-18BP (ectvIL-18BP), in complex with

38 NSC61610) that disrupt hIL-18 binding to the ectromelia virus IL-18BP.

39 ss of Clr-b cell-surface protein upon VV and ectromelia virus infection of murine cell lines and bone

40 report the impact of vaccinia virus (VV) and ectromelia virus infection on expression of Clr-b and Cl

41 alternative pathways are required to survive ectromelia virus infection.

42 In this study, we characterized the ectromelia virus inhibitor of complement enzymes (EMICE)

43 The EVM1 protein encoded by Ectromelia virus is a member of a highly conserved famil

44 major histocompatibility complex inhibitor, ectromelia virus macrophage host range protein, myxoma v

45 ll responses, in the absence of Ab responses ectromelia virus persists.

46 In summary, ectromelia virus produced EMICE within a few hours of an

47 Intraperitoneally inoculated ectromelia virus was uniformly lethal and achieved simil

48 ion of humans (smallpox) and mice (mousepox [ectromelia virus {ECTV}]) despite the lack of a natural

49 cells prevent mousepox, a disease caused by ectromelia virus, a close relative of the virus of human

50 ere we show that during acute infection with ectromelia virus, the mouse homolog of the human virus o

51 of nine genes in 12 isolates and strains of ectromelia virus, which causes a smallpox-like disease (

52 Ectromelia virus-infected cells expressing the major his

53 observation that the protein synthesized by ectromelia virus-infected cells reacted with only one of

54 sepox, a disease caused by the Orthopoxvirus ectromelia virus.

55 ypox viruses, which are highly homologous to ectromelia virus.

56 ntranasal inoculation with 40,000x LD(50) of ectromelia virus.

57 determined and allows for classification of ectromelia viruses.

58 nd one strain each of cowpox, rabbitpox, and ectromelia viruses.