ライフサイエンスコーパス: effect

1 their partner's decisional conflict (partner effects).

2 asal cells, constituting a tumor-suppressive effect.

3 n process, resulting in a strong synergistic effect.

4 and suggest that BCG could have a protective effect.

5 Our goal is to model and quantify this effect.

6 Darbepoetin alfa resulted in an EPO-sparing effect.

7 the hydrolyzing activity and the antioxidant effect.

8 e severely reduced by the substrate clamping effect.

9 mmune mechanisms that mediate this antiviral effect.

10 r cerebrovascular disease and its subsequent effects.

11 e inhibition generally causes undesired side effects.

12 nd is responsible for the drug's reinforcing effects.

13 itly estimates the covariance between random effects.

14 s, and types of visit and for practice fixed effects.

15 interactions that suppress synthetic lethal effects.

16 esource for studying YAP1/TAZ-TEAD dependent effects.

17 account for important health-related adverse effects.

18 scalated RT, pattern of failure, and adverse effects.

19 sm physiology and function due to off-target effects.

20 ignificant role in mediating its therapeutic effects.

21 loci and to detect and interpret pleiotropic effects.

22 fluenza can produce population-wide indirect effects.

23 nerations, indicating epigenetic transfer of effects.

24 d early in illness but can have serious side effects.

25 oid system-extensively implicated in placebo effects, a clinical phenomenon thought to rely on contex

26 nted the point of stabilization of treatment effect, after the maximum treatment effect was observed.

27 le carbon into sediment, we traced a priming effect and assessed the decomposition and export of pree

28 st stabilities of anthocyanins, hyperchromic effect and colour density, regardless of sweetener used.

29 ion is attributed to both a pai-pai stacking effect and the steric hindrance between substrate and ca

30 al did not identify a significant protective effect and was not designed to evaluate source control.

31 g algorithm that identifies biomarkers' main effects and interactions.

32 e cell therapy (ACT) because of its protumor effects and its role in the cytokine release syndrome.

33 56 peptide agonists have antidepressant-like effects and upregulated AKT/GSK3/EIF4 pathways.

34 ores, does not confer plant growth-promoting effect, and displays altered colony and cell morphology,

35 y can use to better understand environmental effects, and we illustrate this with several substantive

36 TN in both croplands, and the fertilization effect appeared more pronounced in SG.

37 bility of TTR and its antiamyloid inhibitory effect are associated.

38 These enrichment effects are favored in arcs with thick crust, which expl

39 ks of the Anthropocene yet their interactive effects are largely unknown.

40 ugs with anti-inflammatory and anti-fibrotic effects are of promise for improving healing by balancin

41 Since ELS effects are often sexually dimorphic and amygdala proces

42 Two relevant CB7 effects are proposed, a base-catalyst mediated by the CB

43 transcribed during vegetative growth, their effects are suppressed by strong and constitutive silenc

44 cross genomes; accurate predictions of their effects are, therefore, important for understanding thes

45 emia, bNAbs may have T cell immunomodulatory effects as seen for other forms of immunotherapy(3).

46 s may be treated endovascularly with similar effects as unruptured MCA aneurysms.

47 edicted their own decisional conflict (actor effects), as well as their partner's decisional conflict

48 acellular localization, and the pathological effects, as dysfunction of RPEs leads to AMD.

49 the levels in control murine BSM strips, an effect associated with increased JNK2 phosphorylation an

50 Replicating prior work, sustained effects associated with autobiographical recall periods

51 Another limitation is the side effects associated with the treatment of chemotherapy or

52 hen organically bound Fe dominates with this effect because of the strong dependency of iron oxyhydro

53 This memory enhancing effect (behavioral tagging) is caused by dopaminergic an

54 NtBRC2A probably confers a dominant negative effect by interfering with the branching-inhibitory BRC1

55 almost all trials have quantified treatment effects by using the hazard ratio, which is difficult to

56 Interaction effects can change materials properties in intriguing wa

57 Due to a memory effect, changes of NH protection during antibody binding

58 ential expression analysis and reduces batch effect compared with other existing methods.

59 increasing understanding of the detrimental effects conferred by broad-spectrum antibiotic use on th

60 cificity, preterm delivery, maternal adverse effects, congenital birth defects, childhood cancer.

61 We illustrated that batch-effect correction can dramatically improve sensitivity i

62 This oculomotor inhibition effect could be considered a marker for the formation of

63 , each with very small effects, whose causal effects could not be individually identified.

64 We fitted mixed-effects Cox regression models adjusting for multiple pre

65 Random effects dose-response meta-analyses were used to estimat

66 were significant but smaller than the direct effects, during the 14-y model simulation period.

67 inherited risk alleles, weighted by allelic effects established in an independent population.

68 justed uncertainty estimates in the reported effect estimate at low concentrations (i.e., concentrati

69 mporal trends, (2) inefficiency in treatment effect estimation, (3) volatility in sample-size distrib

70 we introduce a novel method of photodynamic effect evaluation through in situ detection of specific

71 ing in vitro data to anticipate such in vivo effects exist.

72 med to identify molecular mediators of these effects, focusing on long-lasting epigenetic changes.

73 always be developed by looking at potential effects from the perspectives of the animals and ecosyst

74 methods in cellular populations without side effects has remained challenging.

75 These health effects have not been translated into economic costs for

76 apoptosis in MESN cells, while having little effect in MYCNA lines.

77 some 2 replicated with the same direction of effect in the second brain tissue (BA25, N = 60) from th

78 served symmetries of the anomalous Josephson effect in the vectorial magnetic field are in agreement

79 We validated its effects in an in vitro model of MI/IRI in mammalian card

80 death or all-cause death or to characterise effects in clinically important subgroups.

81 howed different synergistic and antagonistic effects in combination with clindamycin.

82 The prospect of EDCs causing adverse health effects in humans and wildlife has led to the developmen

83 lack of information about Gdf15 activity and effects in normal kidney and in AKI.

84 broblast growth factor 12, with differential effects in patients compared to controls.

85 a significant proportion of Tregs, the side effects in the presence of ART prevent their clinical us

86 xplain the absence of population-level Allee effects in this species.

87 several decarboxylating pathways in the Kok effect, including the malic enzyme.

88 ery of respiratory activity normalized these effects, increasing oxygen supply, restoring optimal dia

89 ) in which the linear predictor takes random effects into account.

90 on of charge and spin currents via spin-Hall effect is essential for spintronics.

91 The time-of-day effect is large, and exceeds the time difference between

92 ions of adjacent atomic layers, whereas this effect is limited in BP lattices due to their spring-sha

93 This effect is mirrored by subunit-selective agonists and het

94 This effect is not mitigated by solar geoengineering.

95 This effect is strongest when stimuli are presented closer to

96 Based on primary and beta-secondary isotope effects, it is established that the isomerization of epo

97 The macromolecular prodrug has no anesthetic effect itself unless irradiated with a low-power blue li

98 bservations of a significant kinetic isotope effect (k(H) /k(D) =5.7) for the reactions of diphenyl e

99 Large intramolecular (13)C kinetic isotope effects (KIEs) for the di-pai-methane rearrangement of b

100 gains for targeted households, but knock-on effects lead to increased harvest of nearshore fish, mak

101 of the Hippo pathway kinase LATS2, and this effect led to subsequent activation of oncogenic YAP.

102 We used mixed-effects linear models to analyze associations of changes

103 ssors not only for a few species, because an effect may be positive in one species but negative in an

104 suggests redundancy of their size-selective effects, meaning that warming will lessen the consequenc

105 es of FH prevalence were pooled using random-effects meta-analyses and were 0.32% (95% confidence int

106 ated the effect of corticosteroids by random-effects meta-analyses using the generic inverse variance

107 M is replaced by the negative binomial mixed-effects model (NBMM).

108 A longitudinal logistic mixed-effects model was used to model daily abstinence from al

109 disease onset, assessed with a linear mixed-effects model.

110 d psoas muscle area on multiple linear mixed-effect modeling (P = .055); however, patient height and

111 ine risk-based variation in benefit, and an "effect-modeling" approach, wherein a model is developed

112 ffects, often referred to as non-consumptive effects (NCEs), are an important feature of predator-pre

113 n disorder may be influenced by myriad small-effect noncoding variants and/or by rare but severe codi

114 zes of interest, revealed that the treatment effects observed in four out of five of our experiments

115 pond to changes in RBP level, recapitulating effects observed in tethered function assays.

116 The inhibitory effect of 4-OI and DMF extends to the replication of sev

117 s instrumental variables to infer the causal effect of a specific risk factor on an outcome.

118 s sufficient to reverse the antihypertrophic effect of ACC2 deletion demonstrating a causal role of e

119 In our population, the effect of Adv36 infection on lipid profile varied betwee

120 We assessed the effect of antiretroviral therapy (ART) on HIV suppressio

121 s remained after backward elimination and no effect of asparaginase or azoles were found.

122 how 14-3-3 relieves the negative regulatory effect of ATP through a 2.5- angstrom-resolution crystal

123 Exercise seems to enhance the beneficial effect of bariatric (Roux-en-Y gastric bypass [RYGB]) su

124 In this study, we explored the effect of calcitriol on homeostatic (M-CSF, TGF-beta-tre

125 Where appropriate, we estimated the effect of corticosteroids by random-effects meta-analyse

126 The effect of CotB2 mutations is studied using multiscale me

127 of terrestrial exoplanets must consider the effect of dust.

128 l-targeted delivery and enhanced therapeutic effect of eHNP-A1-CD15-LDE225 via scavenger receptor cla

129 In this study, we investigated the effect of electromagnetic radiation produced by a number

130 ecies highlights the necessity to assess the effect of environmental stressors not only for a few spe

131 We assessed the effect of ertugliflozin on HHF and related outcomes.

132 patients to colonize GF mice shows a direct effect of fecal microbiota independent of active liver i

133 cape analysis with the aim of maximizing the effect of future research investment through global coll

134 ne manipulation is a common way to study the effect of gene variants on phenotypic traits, but the Cr

135 This study examined the effect of green tea extract at 10 (GWG1%) and 50 (GWG5%)

136 lta or sirtuin-1 showed that the tubulogenic effect of GW0742, but not VEGF-A, was PPARbeta/delta- an

137 In this study, we investigated the effect of intergroup contact on processing of own- and o

138 with an unanticipated cooperative antitumor effect of LDH inhibition and IL-21.

139 We have previously shown that this effect of leptin is mediated by the NMDA subtype of glut

140 The mechanism of the effect of lipid peroxidation, mediated by 4-hydroxynonen

141 This specific effect of lithium suggests that a targeted modulation of

142 gression models and tested for the mediating effect of low birthweight and feeding practices.

143 tunting prevalence and compares the relative effect of major drivers of stunting decline between coun

144 objective of this study was to quantify the effect of maternal heat exposure during early-mid gestat

145 P = .048) (P < .01 for the difference in the effect of moderate alcohol consumption between alleles).

146 fficient modeling to account for the nesting effect of multiple observations within residents and to

147 ns and compared genetic architecture and the effect of natural selection on these blood phenotypes be

148 Here, the effect of PKH labelling on the size of EVs was systemati

149 metric methods, commonly used to measure the effect of policies on economic growth(5,6), to empirical

150 Results indicate the positive effect of rice bran extracts as additives in the food ma

151 om EMPEROR-Reduced, we aimed to estimate the effect of SGLT2 inhibition on fatal and non-fatal heart

152 The effect of the overall topology was examined using severa

153 ak results from a quasistatic magnetic-field effect of the RF radiation for periods comparable to the

154 atory analyses were to: (i) characterize the effect of verubecestat on brain volume by evaluating the

155 The purpose of this study was to compare the effects of 16 weeks of ID exercise versus a HB exercise

156 domized, controlled trial to investigate the effects of a low FODMAP diet on persistent gut symptoms,

157 rvening loop, we investigated the structural effects of a patient-derived CF-phenotypic mutation, E21

158 The effects of a systematic modulation of oxygen over-stoich

159 tein (APP) knock-out (KO) mice to assess the effects of Abetaos on glutamatergic transmission, synapt

160 The effects of age at BCG and time since vaccination were al

161 o from embryonic retinal progenitors for the effects of aging and, independently, of retinal environm

162 redator, further demonstrating the potential effects of changing climates on wildlife species.

163 s offers the promise of mitigating the worst effects of climate change and providing a means to engin

164 rely on contextual processing-modulates the effects of contextual information on emotional attributi

165 ecule spectroscopy allows us to quantify the effects of crowding on a comprehensive set of observable

166 In the current study, we examined the effects of early ketamine exposure on brain structure an

167 Little is known about the effects of eradication of HCV on bone mineral density (B

168 This study examined the effects of exogenous citrulline (control, 1 and 2 mM) an

169 udies have investigated the immunoregulatory effects of exposure to EE, especially in autoimmunity.

170 ts also underscore the potential detrimental effects of Fe(0) and bioaugmentation cultures coinjectio

171 state may significantly influence the health effects of fine PM.

172 Our results suggest that the indirect effects of fire, in addition to the direct emissions, is

173 ework may also help toward understanding the effects of habituation in other more sophisticated neura

174 female human listeners to examine potential effects of hearing loss on EEG correlates of speech enve

175 rovide further insight into the multifaceted effects of HU treatment.

176 on planning explicitly includes the combined effects of human activities and fire regimes.

177 r (TF) that mediates protection from adverse effects of hypertonicity by increasing transcription of

178 rocess and in propagating the antiangiogenic effects of IMiDs in vitro.

179 However, the effects of indoles on goblet cells do not depend on type

180 s other than cigarettes; no trials evaluated effects of interventions on e-cigarette use.

181 This study compared the cardioprotective effects of intravenous statin administration during myoc

182 rrent study was conducted to investigate the effects of irrigation treatments at different physiologi

183 Effects of LAM on resident pulmonary cell types indicate

184 e of state-of-the-art fire models, including effects of land use and the ensemble median or mean comp

185 Here, we aimed to assess the effects of long-term doxycycline treatment on the aortic

186 This study investigated the effects of M.tb infection and BCG vaccination on B cell

187 people with type 2 diabetes the destructive effects of metabolic stress predominate and beta cell de

188 Purpose To investigate the intracranial effects of microgravity by measuring combined changes in

189 als in termite bodies indicating non-thermal effects of microwaves.

190 Although limited by possible confounding effects of mood state, medication, and other mood comorb

191 ed in nature due to the antagonistic fitness effects of mutations in changing environments.

192 ins that can be used to characterize fitness effects of mutations under different stress conditions.

193 Whether the effects of N fertilization vary with bioenergy crop spec

194 We also observe separable effects of Na(+) and succinate binding at several positi

195 Here we compared the electrophysiological effects of native (WT) and p.P888L SAP97, a common polym

196 alpha3beta4* nAChRs regulate the stimulatory effects of nicotine on the mHb-IPn circuit and thereby r

197 amage, ultimately blocking the proneoplastic effects of Nkx3.1 allelic loss.

198 rage age 21.2) in two cohorts and tested the effects of OC on plasma levels of oxytocin, adrenocortic

199 able to environmental changes, but cascading effects of organismal tolerances on the assembly and fun

200 Current research focuses on the effects of public education, implementation of protocols

201 .Objectives: To comprehensively evaluate the effects of rare SERPINA1 variants on lung function and e

202 To study the effects of regional versus local anesthesia on longer-te

203 tational scanning (DMS) datasets probing the effects of single amino acid variation on enzyme activit

204 evolution; the wavelength dependence of the effects of solar radiation on biological and ecological

205 y provides Class IIb evidence for beneficial effects of STN-DBS on NMS at 36-month follow-up which al

206 ns (SVs) to understand the distributions and effects of SVs across TADs.

207 trasound can reversibly alter the inhibitory effects of tetrodotoxin (TTX) in pharmacological studies

208 study focuses on delineating the regulatory effects of the SUMO-SIM interaction on ICP0 E3 ubiquitin

209 nlinearities and low-pass filtering, but the effects of the transformation on analyses of neural popu

210 ing at several positions suggesting distinct effects of the two substrates.

211 The anti-inflammatory effects of vagus nerve stimulation are well known.

212 AI for skin cancer diagnosis to address the effects of varied representations of AI-based support ac

213 The indirect effects of warming on VOC emissions were significant but

214 iochemical kinetics to quantify the combined effects of water content, body size and temperature on p

215 Enemy-risk effects, often referred to as non-consumptive effects (N

216 .48; P = 0.02) increase in hemoglobin but no effect on anthropometry or iron or vitamin A deficiencie

217 The negative effect on apparent survival was stronger with increasing

218 Furthermore, a synergistic effect on breast cancer (MCF-7) and melanoma (SK-MEL-5)

219 tle, but still sufficient to produce a large effect on CA-SP1 cleavage.

220 1 RAs and SGLT-2 inhibitors have a favorable effect on certain cardiovascular outcomes.

221 volume through the length elongation has no effect on either the peak wavelength or intensity of the

222 proteins showed, on the one hand, a negative effect on electron transfer and, on the other hand, impr

223 Provider COC had a greater effect on end-of-life care expenditures than site COC di

224 This effect on ETC complexes appears to be independent of pro

225 We found no effect on health-related quality of life measures, perce

226 l acetate extract had the highest inhibitory effect on heat-induced protein denaturation.

227 ing, osa knockdown had a particularly strong effect on immune effectors that are predominantly activa

228 m's role in this response and the receptor's effect on intercalated and principal cell function in th

229 , which were less intrusive and had a milder effect on membrane pore structure.

230 tion with endometrial cancer but had limited effect on other cancer types.

231 The temperature had a small effect on recovery, but significant differences were obs

232 ombination of both factors had no additional effect on the bioactive potential of yogurts.

233 are conventionally considered to have little effect on the reaction products.

234 Nevertheless, the epidemic's overall effect on the RRT population remained remarkably limited

235 odialysis, but have no significant favorable effect on VC progression.

236 ulated mTOR pathway activation but showed no effect on viability.

237 suggests that flecainide has antiarrhythmic effects on AF due to impaired Pitx2 by preventing sponta

238 Melanoidins did not exert cytotoxic effects on Caco-2 and HUVEC cells (viability was >80%).

239 However, neither trial was powered to assess effects on cardiovascular death or all-cause death or to

240 ous HSP70s, HSPA1A and HSPA1L, have opposing effects on cellular handling of various substrates.

241 strong connections to genes with established effects on CFTR trafficking and function and suggested n

242 he reduction in length but could not predict effects on development of the liver, which was the tissu

243 ough common variants individually have small effects on disease risk, GWAS provide a powerful opportu

244 show that hurricanes have negative short-run effects on economic activity, with losses likely concent

245 be the current best estimate of global fire effects on ecosystems.

246 means to control maturation with unexpected effects on electrical and mechanical function.

247 Transcriptomics confirms transposon-mediated effects on expression of these genes.

248 ave in rodents been shown to have protective effects on glucose homeostasis during high-fat overfeedi

249 sm in order to reveal its local and systemic effects on host health and aging.

250 dependent properties, leading to detrimental effects on immune responses.

251 blood pressure, reduce weight, have salutary effects on left ventricular remodeling, and reduce hospi

252 However, its effects on OPOA remain unclear.

253 rates of plant diversification through their effects on pollen dispersal.

254 ongside efficacy testing of novel therapies, effects on pulmonary pathology and disease progression a

255 impulsive traits explain childhood trauma's effects on SI variability and whether those with highly

256 thenyl]-1H-pyrazole 2l 1) caused significant effects on the cell cycle in PC3 cells, with the vast ma

257 Additional analyses probed stress effects on the dorsal hippocampus (HPC), basolateral amy

258 nctional theory (DFT) showed water has minor effects on the reaction thermodynamics, primarily attrib

259 different relative orientations had opposite effects on the RNA-unwinding activity of the N-terminal

260 capes for mobile consumers driving bottom-up effects on their population sizes, morphologies and repr

261 Psychological stress has adverse effects on various human diseases, including those of th

262 omenon (sometimes referred to as the testing effect or as retrieval-based learning) and consider dire

263 cally significant difference in IOP-lowering effect or tolerability.

264 es in the same model, apoB retained a robust effect (p < 0.05), whereas the estimate for LDL choleste

265 hods allows for the prediction of regulatory effects per variant on several cell type-specific chroma

266 ty profile, intrinsic solubility, common-ion effect, pK(a), pH(max), and K(sp) values of three model

267 all inferior to the best performing variant effect predictors for identifying pathogenic mutations.

268 anistic insight into the opposing functional effects produced by mu-opioids within the OFC.SIGNIFICAN

269 ive phenotypic variation, although the cause-effect relationships are difficult to discern, calling f

270 These effects remained significant after excluding nonrandomiz

271 to disease or merely represents a bystander effect remains unclear.

272 ions; however, the molecular basis for these effects remains unknown.

273 e survival and, through a post-vernalization effect, reproductive output.

274 Subtle conformational effects seen for singly charged metals differ profoundly

275 The pooled treatment effects showed consistent benefits for subgroups based o

276 Second, we find evidence of a segregation effect, since mobility contraction is stronger in munici

277 ngulate cortices in schizophrenia with large effect sizes (Cohen's d = 0.8-0.9), but there was no sig

278 lence testing, using study-specific smallest effect sizes of interest, revealed that the treatment ef

279 adiation damage usually leads to detrimental effects such as embrittlement, accelerated creep, phase

280 se evoked by motoneuron output and that this effect survives a sciatic transection.

281 mic growth(5,6), to empirically evaluate the effect that these anti-contagion policies have had on th

282 t microbiota to the brain and discuss direct effects that gut bacterial molecules are likely exerting

283 To combat this effect, this work assessed a novel cyclical aggregation

284 wn about the extent to which CodY exerts its effect through small regulatory RNAs (sRNAs).

285 xerts potent pro-invasive and pro-metastatic effects through directly binding to Vimentin and competi

286 a multigate electrolyte gated organic field-effect transistor (EGOFET) with a 6.5 muL microfluidics

287 re sensitive than traditional graphene field-effect transistors.

288 etworks, Neuro-Oncology, Oncology, Treatment Effects, Tumor Response Supplemental material is availab

289 s tubulin polymerization in vitro; 4) had no effect upon the polymerization of the bacterial cell div

290 This effect was not related to the abundance of platinum comp

291 This effect was not retinotopically specific, suggesting that

292 A similar effect was observed upon NaCl exposure.

293 reatment effect, after the maximum treatment effect was observed.

294 To further explore these effects, we implemented a computational model of the hip

295 opment and survival, and chromatin landscape effects, we show that the SE ensures robust Atoh7 transc

296 These effects were diminished upon the same treatment of A549

297 ing, suggesting that direct rainfall forcing effects were predominantly driven by sea-surface tempera

298 col, inspired by the fractional quantum Hall effect, where the DDS basis is isomorphic to a set of de

299 er of genetic variants, each with very small effects, whose causal effects could not be individually

300 These effects will worsen with ongoing dependence on this ener