ライフサイエンスコーパス: effect

1 the model (e.g. with and without antecedent effects).

2 prehension, whereas donepezil had a negative effect.

3 erminal-specific antibody (Tau46) had little effect.

4 the presence of oxygen to elicit a cytotoxic effect.

5 icted channel-facing positions modulate this effect.

6 studies should aim to confirm this possible effect.

7 differences to the demonstration of the drug effect.

8 dherence and reduce adverse gastrointestinal effects.

9 nd does not seem to possess emetic-like side effects.

10 versibility of the photoresponse to charging effects.

11 annel-blocking drugs with divergent clinical effects.

12 lving increased GFR and vascular and tubular effects.

13 rove drug specificity by reducing off-target effects.

14 c unit of 1.85 indicating less than additive effects.

15 of patients reported opioid-induced adverse effects.

16 y) as a consequence of cancer cell-intrinsic effects.

17 produces similar analgesia with reduced side effects.

18 d to assess longer-term efficacy and adverse effects.

19 ead to significant compositional segregation effects.

20 comment on long-term antibody sensitisation effects.

21 the antibiotics and elucidate potential side effects.

22 ed to show noninferiority of GSH-I (adjusted effect, 1.47; 95% CI, -0.01 to 2.91; P = .05).

23 iry date and retained significant inhibitory effects against colon carcinoma (CaCo-2) cells.

24 PP mice; and that SS31 may confer protective effects against mitochondrial and synaptic toxicities in

25 s overall, although there may have been some effect among Fusarium ulcers.

26 ound to exhibit excellent anti-proliferative effects among the tested xanthones.

27 ntellectual disability abolished the spacing effect and led neurons to decode distinct stimulation pa

28 op methods that are robust to platform/batch effects and able to identify perturbed pathways in indiv

29 n between ketamine's clinical antidepressant effects and circadian timekeeping.

30 model the importance of multiple scattering effects and computationally predict the impact of local

31 ed lower concentrations to exert anti-cancer effects and preferentially affected GSCs and telomeres.

32 dmission use of drugs with anti-inflammatory effects and risk of new-onset depression and anxiety amo

33 The spectral sensitivity of these effects and their substantial reduction in melanopsin kn

34 in diameter without ring-enhancement or mass effect, and homogenous T2 signal abnormality not signifi

35 arity, precision, accuracy, recovery, matrix effect, and stability were studied.

36 intensity required for meaningful treatment effects, and determine whether treatment effects cumulat

37 These cardiovascular effects appear to be mediated by paracrine FGF control o

38 olyphenol metabolism and possible toxic side effects are also considered.

39 These effects are modestly augmented by the addition of a long

40 In addition to the aPL thrombophilic effect, arterial thrombosis was related to accelerated a

41 power in human piriform cortex, with robust effects at the level of single trials.

42 ce of sterile inflammatory processes in this effect been revealed.

43 significantly higher fractions of SAVs with effect between healthy individuals than between species;

44 o evaluate linear, quadratic and interaction effects between fermentation parameters.

45 We observed interaction effects between self-reported health status and treatmen

46 We estimated these contagion effects by combining daily global weather data, which cr

47 This effect can be partially mimicked by stimulation of Hmox1

48 These effects can be recovered by culturing cells in the prese

49 icant difference in k0 is due to a tunneling effect caused by the adsorption of the electrolytes on t

50 These contrasting patterns of modulatory effects could allow PMd and PMv to play distinct functio

51 rietal sulcus of the developing brain, those effects could be explained by patterns of neural activit

52 These deleterious effects culminated in the activation of the mitochondria

53 ent effects, and determine whether treatment effects cumulate over repeated intervention periods.

54 High mobility graphene field-effect devices, fabricated on the complex-oxide heterost

55 Survival analyses indicate that arrest effects endured up to 5 years.

56 The effect estimates were robust to PM10 adjustment.

57 production of lactate from glucose (Warburg effect), extensive glutamine utilization and impaired mi

58 n participants compared with controls (group effect, F = 8.0; P = .006).

59 roup than for the NR-E group (treatment main effect: F1,68 = 5.4, P = .02, d = 0.50, and Delta = 2.4

60 ional quality but cause negative pleiotropic effects for reasons that are not fully understood.

61 ixed models estimated the plausible range of effects for television consumption, nutritional status,

62 In this study we investigated these effects for US and Yucatec Mayan infants, children, and

63 ds, and little is known about the downstream effects from this modulation.

64 effective, since it reduced both the matrix effect (from values between -40 and -10% to values from

65 There appears to be both an anticipatory effect (future targeted procedures reducing readmission

66 To date, the quantum anomalous Hall effect has been investigated using low-frequency transpo

67 tematic, experimental investigations of this effect in four field studies (study 1: n = 870; study 2:

68 The anion exclusion effect in HM is thus more pronounced than that in OPA, e

69 scopy to identify and characterize a support effect in oxide-supported heterogeneous Rh catalysts.

70 However, scopolamine was without effect in the aversive procedure, revealing the importan

71 ASO7 had a similar effect in the BAC-Q72 SCA2 mouse model, and in both mous

72 rtality rates, we observed a very beneficial effect in the neonatal period.

73 most frequently reported mechanism of Allee effects in animals.

74 y for broader exploitation of grain-boundary effects in heterogeneous catalysis.

75 esearch shows evidence of numerical distance effects in the intraparietal sulcus of the developing br

76 ver, some GBCAs have a small risk of adverse effects, including nephrogenic systemic fibrosis (NSF),

77 ular domain of IL1RAPL1 is required for this effect, independently of the interaction with PTPdelta,

78 We manipulate the LDOS via field effect-induced optical permittivity modulation of an ult

79 Despite its known detrimental effects, iron deficiency remains the most common micronu

80 The inverse Faraday effect is approximately the same in Fe, Ni and Co, but t

81 Recently, a novel pyro-phototronic effect is invented as an alternative approach for perfor

82 Accurate evaluation of the volume exclusion effect is made possible by the choice of yeast frataxin,

83 The direction of this effect is opposite to that predicted by contemporary the

84 This effect is realized in the approach referred to as "trime

85 The relevance of polar effects is supported by theoretical calculations conduct

86 pecies, and trimethylamine-N-oxide), thus in effect linking diverse exposures such as those from diet

87 These cumulative effects may result in downstream phenotypic consequences

88 We conducted a fixed-effects meta-analysis, including, to our knowledge, the

89 By introducing Al2 O3 capping, carrier field effect mobilities (41 for holes and 80 cm(2) V(-1) s(-1)

90 to laminar depth were determined with mixed-effects modeling.

91 e modeling, Markov chain analysis, and mixed-effect models were used to investigate shifts in the mic

92 We have extended the framework of Nested Effects Models (NEMs), a type of graphical model specifi

93 Mixed effects models and log binomial models were used to asse

94 odynamic trends derived from nonlinear mixed-effects models showed small early favorable changes in t

95 before payments implemented) and a spillover effect (nontargeted procedures also reducing readmission

96 ies increased, with a significant cumulative effect occurring during grazing years.

97 tudy reports a comprehensive analysis of the effect of 100 mus electric pulses on the biochemical com

98 among negative feedback loops, such that the effect of a negative feedback depends on its position wi

99 ds to the limited evidence of the protective effect of adherence to a Mediterranean dietary pattern i

100 More specifically, we investigated the effect of agenesis of the corpus callosum (AgCC), one of

101 The effect of an impaired sweet-taste perception system on c

102 This inhibitory effect of BECs was significantly reduced in the stable L

103 research has established the bronchodilatory effect of bitter taste receptor (TAS2R) agonists in vari

104 The effect of cAMP on Fe(II) and 5hmC was confirmed by adeny

105 We combine the collateral effect of Cas13a with isothermal amplification to establ

106 umour, we evaluate its fitness as a weighted effect of dominant neoantigens in the subclones of the t

107 n in trans was demonstrated by examining the effect of E6APC820A on wild-type activity and single-tur

108 In contrast, no effect of embryo genotype was seen in concepti from hete

109 1 (PKD1) in tumor cells, we investigated the effect of excitotoxicity on neuronal PKD1 activity.

110 The inhibitory effect of F4 was not mediated through the inhibition of

111 ergy intake and energy exchange enhanced the effect of free sugars on total and LDL cholesterol and t

112 eplication origins connecting the long-known effect of genomic context on replication timing to genom

113 sed mortality after transplantation, but the effect of glycemic control on survival is unknown.We sou

114 To assess the effect of high-dose spironolactone and usual care on N-t

115 hanistic basis for the dominantly protective effect of HLA in autoimmune disease, whereby HLA polymor

116 The mechanism underlying the effect of ILT3.Fc on tumor cell growth involves inhibiti

117 The effect of iron incorporation into DrDps2 was investigate

118 inding: we observe both a direct stabilizing effect of ligand-protein interactions and an indirect de

119 In this study, we investigate the effect of loss of P2X7 receptor function on retinal stru

120 In this study, we explore the effect of low dose N-acetyl-L-cysteine therapy, delivere

121 We sought to establish the effect of MABp1 with a new primary endpoint in patients

122 The same effect of macrophage infiltrate on EGFR activation was a

123 ional prediction was used to investigate the effect of MDD-associated SNPs within the regions.

124 lso investigated the putative prohemorrhagic effect of NAC in a mouse model of intracranial hemorrhag

125 ; P = .03), whereas there was no significant effect of negative microscopic resection margins (AHR, 0

126 ose-stimulated insulin secretion (GSIS), the effect of obestatin on GSIS is unclear.

127 ve evidence from RCTs designed to assess the effect of omega-3 polyunsaturated fatty acid supplementa

128 To assess the effect of pelvic drainage after rectal surgery for cance

129 The combined effect of pH (from 2 to 6.5) and nitrite (from 0.1 to 20

130 The effect of pirfenidone on death after hospitalization is

131 We analyze the effect of precipitation type on mercury wet deposition u

132 The effect of previous immunity on incidence was also invest

133 diting activity, as well as the antagonizing effect of RBP binding on miRNA repression.

134 The aim of this study was to examine the effect of RDN on mean arterial pressure, renal function,

135 Our investigations revealed no effect of retinoschisin on Na/K-ATPase-mediated ATP hydr

136 We assessed the effect of selection for tracing using Kaplan-Meier estim

137 ngs provide new insights into the inhibitory effect of SFN on HCC tumor angiogenesis as well as tumor

138 In words, the effect of space is equivalent to making changes in the p

139 , and adipocytes, which is distinct from the effect of STING activation by DMXAA on enhancing proinfl

140 Moreover, the effect of the addition of the synthetic antioxidant 2,6-

141 A multivariate analysis showed a significant effect of the campaign in the SLSJ region (relative B-IM

142 The effect of the chlorogenic acid isomer 5-O-caffeoylquinic

143 The effect of the G4-ligands on Panc-1 cancer cells has also

144 We sought to investigate the effect of the HIV-1 auxiliary protein, Nef, which is sus

145 There was a quenching effect of the honey matrix on leptosperin fluorescence b

146 s evaluated, especially by investigating the effect of the presence of xylose during glucose measurem

147 and monocytes for sex, we detected a direct effect of these intrinsic factors for the majority of im

148 ch is critically involved in the reinforcing effect of tobacco smoking.

149 lectropherograms of samples demonstrated the effect of treatment parameters on composition of LWE pro

150 We also find that the combined effect of urban form on NO2 is larger for small cities (

151 ial guinea pig neonate demonstrated that the effect of vasopressin is not dependent on the level of m

152 malformations to identify differences in the effect of virtual corpus callosotomies and the neurodeve

153 e of trees, efforts to predict the long-term effects of a changing climate on tropical forests must t

154 We studied the effects of acute physical exercise on the cerebral mu-op

155 hough specific cell populations mediated the effects of age and sex on gene expression, including CD8

156 Further study is required to test effects of agents that target the NO pathway in reducing

157 The potential therapeutic effects of agonistic analogs of growth hormone-releasing

158 The effects of amino acid replacements on lipid association

159 To investigate the effects of ARHGAP29 in vivo, we generated a novel murine

160 The effects of AURKA overexpression associated with poor cli

161 Recently, we have demonstrated beneficial effects of autophagy-activating digitalislike compounds

162 -talk with other signaling pathways, and the effects of betaAR-directed drugs.

163 To compare the effects of both variants with known inactive GDP- and ac

164 estimate actual mortality rates and quantify effects of bycatch on populations.

165 MYC expression phenocopied the CSC depletion effects of C1572 and induced senescence in TNBC cells.

166 These findings demonstrate residual effects of cannabis use whereby global and regional brai

167 SMIT1 activity from the otherwise inhibitory effects of cellular depolarization imposed by elevating

168 ature of neoantigen-specific T cells and the effects of checkpoint blockade immunotherapy.Immune chec

169 The positive effects of chronic steroid treatment in muscular dystrop

170 na's forests and for better understanding of effects of climate and stand characteristics on dead org

171 ys, social status influences the reinforcing effects of cocaine and the effects of some drugs on coca

172 is to investigate the potential therapeutic effects of cortistatin in two well-established preclinic

173 gth on continuity of care and relationships; Effects of day shift length on communication with patien

174 Effects of day shift length on patient care; Effects of day shift length on continuity of care and re

175 There were three overall themes: Effects of day shift length on patient care; Effects of

176 n to affect recurrence to assess independent effects of DEB-TACE response on recurrence.

177 e, including the most recent studies, on the effects of dietary saturated fat intake and its replacem

178 However, the effects of expectation can also be due to decisional cri

179 Purified Wogonin mimicked the effects of F4 in IL-1beta-stimulated OA chondrocytes.

180 reduced GMVs and NAA/Cr, over and above the effects of fatigue, depressive symptoms, physical activi

181 This article reports the effects of fetal bovine serum (FBS), a physiologically r

182 We examined the effects of fire severity on the soil respiration rate (R

183 pplication of these approaches has uncovered effects of gene-environment interactions relevant to dru

184 To investigate the effects of increased CD39 in an in vivo cerebral ischemi

185 Here, we investigated the phenotypic effects of JAK2 deficiency.

186 To study the biological effects of low GSH levels, we disrupted its synthesis bo

187 ces have been attributed to the differential effects of male and female gonadal secretions (commonly

188 elopmental programming and transgenerational effects of maternal exposure to early-life stress on sev

189 The objective of this study was evaluate the effects of moisture and temperature during grain storage

190 Accordingly, we focus not only on the effects of mutant p53 oncogenic gain of function but als

191 We examined the effects of nutrient limitation within a mutualism using

192 regression models were used to evaluate the effects of oral health, general health, and socioeconomi

193 ments and comparable to or stronger than the effects of other well-known drivers of productivity, inc

194 Further characterization of the effects of oxytocin on neural circuits in the hypothalam

195 uterine epithelial cells, and the antitumor effects of P4 are mediated by the endometrial stroma.

196 The beneficial effects of parasympathetic stimulation have been reporte

197 Most prospective studies on the health effects of particulate ambient air pollution exposure ha

198 The effects of PGE2-G required its hydrolysis into PGE2, wer

199 nd poor ability to differentiate between the effects of population prevalence of chronic shedding vs.

200 study provides a potential mechanism for the effects of sildenafil that, through adverse effects on m

201 cal processes that demonstrate the long-term effects of soil contamination.

202 s the reinforcing effects of cocaine and the effects of some drugs on cocaine self-administration.

203 nd 88 are critical for allosteric modulatory effects of SRI-compounds on the interaction of cocaine w

204 The splicing effects of sudemycin and U2AF1(S34F) can be cumulative i

205 The effects of systemic or centrally administered orexin rec

206 icularly sensitive to the anti-proliferative effects of the agent.

207 Effects of the intervention were modified by SNPs in VDR

208 ory functions of RBPs, including the binding effects of the RNA helicase MOV10 on mRNA degradation, t

209 ly flavored foods.We sought to determine the effects of the timing and duration of eating a variety o

210 ions on the rate at which ECs terminate from effects of the TL on the nucleotide addition rate that i

211 t positions, providing new insights into the effects of these modifications and a dynamic view of RNA

212 diversity coupled with differential clinical effects of this diversity suggest that an effective VAR2

213 Here, we analyze effects of this loss and other cochlear loads on TM trav

214 developed a kinetic assay that distinguishes effects of TL alterations on the rate at which ECs termi

215 To that end, the effects of various gene deletions or chemical blocking a

216 n-containing 2 (NOD2); however, the reported effects of XLP-2 and VEO-IBD XIAP mutations on cell deat

217 In contrast, GsMTx-4 had no effect on collagen-induced aggregation or on Ca(2+) infl

218 ased CYP27B1 mRNA levels in HCEC, but had no effect on CYP27B1 protein levels.

219 Different redox states have a profound effect on domain orientation in the enzyme and we analys

220 This shift in absorption and the effect on electron transfer properties is investigated v

221 Blockade of muscarinic receptors had no effect on evoked dopamine release, suggesting that feedb

222 The stimulatory effect on extracellular regulated kinase (ERK1/2) was bl

223 ther health professionals leads to a greater effect on HbA1c, weight, and LDL cholesterol.

224 dings indicate that Abeta has a differential effect on hippocampal proliferative cells by inhibiting

225 n interactions and an indirect destabilizing effect on intraprotein interactions that is induced by t

226 e added to tomato sauce to investigate their effect on its physico-chemical properties.

227 ynthesis of the DiPyrO tag, characterize its effect on labeled proteome analysis by nanoLC-MS(2), and

228 nce exercise training (RET) has a beneficial effect on muscle protein synthesis and can be augmented

229 YFP) or monomeric mutant G85R SOD1YFP had no effect on net ionic currents measured under voltage clam

230 P-PCOCQ subscale, had a significant positive effect on NP role (risk ratio=2.33; 95% CI: 1.06-5.13);

231 GD1a exerts its effect on OPCs by inducing their proliferation and, at a

232 ification or diploidy but had no significant effect on OS.

233 Although a favorable effect on peak VO2 was observed on FCM, compared with st

234 Deletions appear to have the largest effect on pseudogene formation and loss of regulatory re

235 nfluential individuals exerted an overriding effect on risk-taking by the entire group, for reasons i

236 Contrarily, BW pasta had oxidative effect on serum so as conventional pasta and glucose, th

237 terial property of each bead and that bead's effect on SOD1 fibrillization rate was with regard to be

238 n patients with HDM-induced AA and AR, their effect on subsequent guideline updates will depend on th

239 Neonatal BCG had no effect on the development of RW before 13 months of age.

240 n light over a diurnal period to examine the effect on the photosynthetic processes and growth of Ara

241 elongation speed in fungal systems, but its effect on translation elongation speed in animal systems

242 p)/perilipin 2 (Plin2), and investigated its effects on atherogenesis in apolipoprotein E-deficient (

243 demonstrate genetic factors with pleiotropic effects on bone mineral density and lean mass.Bone miner

244 the tumor microenvironment that exert potent effects on cancer metastasis.

245 r, it remains unclear whether MSA exerts its effects on cancer prevention by influencing angiogenesis

246 pathway such as NG2/CSPG4 may have different effects on cell behavior with tumor progression.

247 d motion, frequency and B0 shim changes, and effects on data quality during real-time-corrected three

248 but how such alterations influence cocaine's effects on dendritic spine formation remain unclear.

249 s in inorganic N sources to induce cascading effects on dissolved organic matter (DOM) and microbial

250 Both treatments had neutral effects on glucose metabolism parameters.

251 exerts cell-type-specific anti-inflammatory effects on macrophages, hepatocytes, and adipocytes, whi

252 s, additional functional groups had variable effects on metabolic stability and efficacy, but the mos

253 effects of sildenafil that, through adverse effects on mitochondrial function and endoplasmic reticu

254 nal death in hippocampal neurons via diverse effects on NADPH oxidase activity and dendritic spine mo

255 cific T cells, but less is known about their effects on natural killer (NK) cells, which help control

256 rebral blood volume (CBV) as a proxy of drug effects on neuronal activity.

257 Position-dependent effects on peptide retention for different residues were

258 tors, few studies have directly tested their effects on performance at range limits.

259 this environmental heterogeneity and how its effects on regeneration dynamics play out in long-term s

260 Antimony, which has damaging effects on the human body and the ecosystem, can be rele

261 C-terminal peptide fully recapitulated their effects on the subcellular localization of ProP.

262 non-coding transcript isoforms with opposite effects on transcription recovery after UV-induced DNA d

263 tion is a new marker of response to ART when effects on viremia and clinical response are not met.

264 fector proteins that mediate this protective effect remain poorly defined.

265 a class of lipid mediators, counteract this effect, representing an attractive target for therapeuti

266 nteractions and suggest that non-consumptive effects should not be ignored when assessing the impact

267 In addition, there was a significant group effect showing higher tracer uptake in participants comp

268 complex traits, such as allele frequency and effect size.

269 Effect sizes were reported as odds ratios (ORs) with 95%

270 lied far-infrared and ultrafast optical Kerr effect spectroscopies on carefully selected ions with a

271 erence, which had a top-down explaining-away effect that enabled recognition of an individual part to

272 mall networks, where we found the surprising effect that linear two filament connections act as trans

273 s with the phenomenon of contact gating - an effect that significantly affects the carrier injection

274 A platform strategy will create a network effect that will benefit multiple disease programs.

275 al cornu ammonis 1 and granule cell neurons, effects that were also observed in aged mice, albeit to

276 between type of fractionation and treatment effect, the overall survival benefit being restricted to

277 rease the grating amplitude due to shadowing effects, thereby enabling tailoring of the damping proce

278 ng RNAs that display important physiological effects through their posttranscriptional regulation of

279 use bacteria engineered with a strong Allee effect to investigate how the frequency of periodic spat

280 ndothelial caveolae in vivo and compared its effects to non-caveolar target CD31/PECAM-1.

281 the pH sensitivity of an Ion Sensitive Field Effect transistor (ISFET) sensor can be significantly en

282 light-emitting diodes (OLEDs), organic field-effect transistors (OFETs), solar cells or other light h

283 stigated for solution-sheared films in field-effect transistors demonstrating that SBT can enable goo

284 rom the source electrode in back-gated field effect transistors.

285 Considering uncertainty in both cost and effect using a wide range of willingness to pay threshol

286 This treatment effect varied, however, depending on baseline severity o

287 a agent-based modeling (ABM) and hemodynamic effects via computational fluid dynamics (CFD).

288 ng those with cAVB in the chronic phase, the effect was attenuated (hazard ratio, 1.16; 95% confidenc

289 The most common adverse effect was decreased blood calcium (68.9% vs 59.8%).

290 iver regeneration) in control mice, but this effect was delayed in interleukin 6-deficient mice.

291 This grain length effect was fine-mapped to a 4.3 cM interval.

292 andard of care in the primary analysis, this effect was highly sensitive to the imputation strategy f

293 2+) responses in MNCs of sham rats, but this effect was occluded in RVH rats, thus equalizing the mag

294 ively associated with some outcomes, but the effect was partly mitigated by the organisational factor

295 The effects we find are nearly identical between thymus and

296 Rates of discontinuation due to side effects were lower among those taking RPT/INH.

297 No significant treatment effects were observed for duration or severity of other

298 d gradient force enable to avoid overheating effect while maintaining mechanical stability even under

299 l be needed to assess possible herd immunity effects with meningococcal serogroup B vaccines and the

300 KD risk groups had multiplicative predictive effects, with no evidence of an interaction (p = 0.329 a