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1 the first cohort assessed for the safety and efficacy of 12 weeks of sofosbuvir plus ribavirin for th
2 brile influenza-like illness with an overall efficacy of 19% (95% CI 1 to 34) in the combined cohorts
4 I 2545-2759) per QALY gained for a treatment efficacy of 20% and euro4243 per QALY gained for treatme
6 ticipants in the Vi-PS group to give vaccine efficacies of 54.6% (95% CI 26.8-71.8) for Vi-TT and 52.
7 inclusion criteria, with an average two-dose efficacy of 58% (95% CI 42-69, I(2)=58%) and effectivene
8 vitro and in vivo the potency and protective efficacy of 5C4 and the murine precursor of palivizumab,
10 of BRV-PV, an oral rotavirus vaccine, had an efficacy of 66.7% against severe rotavirus gastroenterit
15 mune responses that predict the preventative efficacy of a human immunodeficiency virus (HIV)-1 vacci
16 bo-controlled trial in Niger to evaluate the efficacy of a live, oral bovine rotavirus pentavalent va
17 embling ability) of small molecules with the efficacy of a molecule process against cancer cells, thi
18 his randomized controlled trial examined the efficacy of a novel gaze-contingent music reward therapy
20 ose of the current study is to determine the efficacy of a PI3K/mTOR dual inhibitor, LY3023414, on es
21 irst randomised controlled trial to document efficacy of a remyelinating drug for the treatment of ch
22 gated the scope for enhancing the protective efficacy of a single dose adenovirus-vectored malaria va
23 e present study was to assess the safety and efficacy of a standard rapid desensitization protocol in
28 risk, and evidence is lacking regarding the efficacy of alendronate to protect against hip fracture
29 objective of this study was to determine the efficacy of alginate staple-line reinforcement of fissur
31 s multiple sensitivity analyses, whereas the efficacy of all the other strategies was questioned by r
33 emonstrated safety and clinically meaningful efficacy of allo-hMSC versus auto-hMSC in NIDCM patients
34 ss North America to determine the safety and efficacy of allogeneic human mesenchymal stem cells (MSC
35 ngly, we observed the aggregation inhibitory efficacy of alpha/beta and alpha/gamma BSBHps, but not o
37 firm that HDAC6 inhibition augments in vitro efficacy of anti-CD20 mAbs and improves survival of mice
40 4 signaling significantly enhanced treatment efficacy of anti-VEGFR2 treatment in both CRC models.
43 ese organisms is intimately dependent on the efficacy of antifungal agents; however, fungi that are r
46 study the impact of hypoxic necrosis on the efficacy of antimycobacterials and drug candidates, we s
47 of randomized clinical trials comparing the efficacy of antipsychotic drugs combined with other anti
49 ntly greater and more sustained antileukemic efficacy of ATO-ATRA compared with ATRA-CHT in low- and
52 and high-quality evidence for the safety and efficacy of atraumatic needles as a superior option for
53 ducted a randomized comparison of safety and efficacy of autologous (auto) versus allogeneic (allo) b
55 No definitive comparative studies of the efficacy of 'awake' deep brain stimulation (DBS) for Par
57 uate the feasibility, safety, and short-term efficacy of bariatric embolization, a recently developed
59 causing little skin irritation, vaccination efficacy of BCG-MNAs was comparable to that of intraderm
60 e of this trial was to assess the safety and efficacy of benralizumab for patients with mild to moder
61 f HPAI A(H5) viruses in Vietnam, the vaccine efficacy of bivalent poultry vaccine formulations should
67 unometabolic adjuvants to safely enhance the efficacy of cancer immunotherapy, radiotherapy, or 'immu
69 o study polio pathogenesis and to assess the efficacy of candidate antiviral drugs and new vaccines.I
71 mmonly discussed bony defects when comparing efficacy of CBCT versus intraoral radiographs (IRs).
72 hers previously reported potent antileukemia efficacy of CD123-redirected chimeric antigen receptor (
75 These data rationalize the observed clinical efficacy of ceftazidime/avibactam plus aztreonam as comb
76 s CGRP to trigger migraine in humans and the efficacy of CGRP receptor antagonists that evidently do
78 d with clinical outcomes and may predict the efficacy of chemotherapy and human epidermal growth fact
80 udy, we examined the long-lasting protective efficacy of chimeric VLPs (cVLPs) containing influenza H
83 administration did not impair the anticancer efficacy of cisplatin and radiotherapy in tumor-bearing
85 patients and whether adenosine restricts the efficacy of clinically approved targeted therapies for c
91 n vivo experiments to confirm the safety and efficacy of compound 8; the compound was found to be ora
92 vely, these findings demonstrate the in vivo efficacy of CR6261 and CR9114 against H2 viruses and emp
94 available evidence on the ocular safety and efficacy of current therapeutic alternatives for the man
96 al vaginosis and high adherence to PrEP, the efficacy of daily oral PrEP for HIV prevention did not d
98 in developing a robust evidence-base for the efficacy of de-escalation is striking and must, at least
99 specific white matter (WM) pathways, and the efficacy of deep-brain stimulation relies upon activatio
101 thematical framework is devised to allow the efficacy of different candidates to be directly compared
102 matic review and metaanalysis to examine the efficacy of different intermittent dosing schedules in f
103 METHODS AND We comparatively analyzed the efficacy of different lipid formulations in delivering h
104 The aim of this study was to explore the efficacy of dimethyl fumarate (DMF) in preventing diseas
105 f therapy and optimal end points to evaluate efficacy of drugs in clinical practice and trials, exist
109 further studies should elucidate whether the efficacy of ectoparasite removal by cleaners is affected
110 for-age z score of 0.63.We aimed to test the efficacy of eggs introduced early in complementary feedi
111 EXTEND study evaluated long-term safety and efficacy of eltrombopag in adults with ITP who had compl
113 several targeted therapies that enhance the efficacy of endocrine therapy; inhibitors of mTOR and in
115 BAT mass and activity and thus the potential efficacy of envisioned drugs targeting this tissue to tr
116 acterium tuberculosis (Mtb) that reduces the efficacy of ethionamide, a second-line antitubercular dr
117 lly in their calcium channel composition and efficacy of excitatory inputs in the presence of dopamin
120 col development) will determine the clinical efficacy of fosfomycin as step-down oral therapy to trea
122 itory synapses, leading to reductions in the efficacy of GABAergic inhibition via a postsynaptic mech
124 ale clinical trials are needed to assess the efficacy of gammaT supplements as a complementary or ste
125 itinib trial tumors was conducted to compare efficacy of gefitinib with that of placebo according to
126 eligible trials that assessed the safety and efficacy of GLP-1 receptor agonists compared with placeb
127 ed, fixed-dose clinical trial evaluating the efficacy of GSK561679, a corticotropin-releasing factor
130 epigenetic mechanisms underlying AUD and the efficacy of HDAC inhibitors (HDACIs) in different animal
133 den and the United States) that assessed the efficacy of IdeS with regard to desensitization and tran
135 cally incompatible; (ii) early monitoring of efficacy of immunotherapies; and (iii) personalizing an
138 l data have yet to demonstrate the analgesic efficacy of inhibitors of endocannabinoid-regulating enz
139 The aim of this study was to investigate the efficacy of intraperitoneal local anesthetic (IPLA) on p
141 uture studies should evaluate the safety and efficacy of intravenous rt-PA in patients with ischemic
143 ase II and III clinical trials to assess the efficacy of IRE plus chemotherapy in the neoadjuvant and
147 ween LCI and non-LCI cases and estimated the efficacy of LAIV against moderate-to-severe LCI and othe
148 al to evaluate the safety, tolerability, and efficacy of ledipasvir and sofosbuvir plus ribavirin in
149 th ledipasvir failure, pointing to a limited efficacy of ledipasvir in patients with genotype 3.
150 Recently, several studies have examined the efficacy of low dosage red light exposure for cellular r
154 of acute cardiovascular events, despite the efficacy of many therapies for patients with heart failu
155 -2 in IGF2-overexpressing CRC models and the efficacy of MEDI-573, an IGF-1/2-neutralizing antibody.
156 el blockers for their ability to improve the efficacy of Metarhizium against wild-caught, insecticide
157 n of opioid receptors limits the therapeutic efficacy of morphine-like analgesics and mediates the lo
158 The TA and PL data clearly illustrate the efficacy of MoS2 and likely other TMDC materials as ener
159 clusion, lung epithelial cells influence the efficacy of most antimicrobials against P. aeruginosa bi
162 omposition of wetland GHG emissions, and the efficacy of multiscale flux measurement to overcome chal
166 easing evidence that supports the safety and efficacy of neuroleptics and neuromodulatory approaches
174 ificantly enhance or decrease the anti-HIV-1 efficacy of nucleotide analogue reverse transcription in
176 mmune signaling contributes to the decreased efficacy of opioids, and we recently demonstrated that T
177 deficiency anemia to compare the safety and efficacy of oral ferric citrate (n=117) and placebo (n=1
178 The findings of this study suggest that efficacy of oral rabies vaccination by aerial delivery i
179 d randomized controlled trials exploring the efficacy of oral tolerance induction in infancy for the
181 by these isomers was used as a proxy for the efficacy of orbital overlap and therefore ligand binding
185 We also show that such inhibitors heighten efficacy of our nanobiologics on naive tumors by augment
186 sistance and further enhance the therapeutic efficacy of paclitaxel in paclitaxel-resistant prostate
189 have now expanded this study to evaluate the efficacy of PD-1 blockade in patients with advanced mism
190 is to improve the clinical response rate and efficacy of PD-1-PD-L1 blockade in patients with cancer.
194 ngiography (CTCA), and assess the safety and efficacy of percutaneous coronary interventions (PCIs).
202 Any RCT comparing mortality or clinical efficacy of prolonged (continuous or >/=3 h) versus shor
203 candidate markers to monitor the therapeutic efficacy of psychostimulants or to predict therapeutic r
207 tudy, we evaluated the safety and protective efficacy of recombinant unglycosylated RSV G protein ect
210 n through RAR/PR cross talk, may explain the efficacy of retinoids in prevention of some breast cance
211 lpha9-containing nAChRs as the basis for the efficacy of RgIA4, and that alpha9-containing nAChRs are
212 oninferiority design the relative safety and efficacy of ridaforolimus-eluting stents (RESs) and slow
216 statistically significant difference in the efficacy of second-generation antidepressants (SGAs) ver
217 12-month intraocular pressure (IOP)-lowering efficacy of selective laser trabeculoplasty (SLT) as sol
218 s study aims at characterizing the antitumor efficacy of sesamol and unveiling the importance of mito
219 rugs and plays a role in the disposition and efficacy of several opiates, antidepressants, statins, a
220 resulted in intense efforts to evaluate the efficacy of several specific countermeasures developed t
221 Th1 or Treg cells mainly contributes to the efficacy of SIT by helping B cells to produce neutralizi
222 f this study was to evaluate the therapeutic efficacy of site-specifically conjugated duocarmycin- an
224 Is, and formulate predictions concerning the efficacy of spike-triggered conditioning in different re
225 ose-dependently, while the anti-inflammatory efficacy of standard curcumin remained constant, suggest
228 sor is evaluated to monitor the microbicidal efficacy of sterilization processes applying gaseous hyd
235 amination of published data on the potential efficacy of targeted therapies showed theoretically acti
236 tic rationale to investigate the therapeutic efficacy of targeting the MALT1-MYC axis in MCL patients
238 tive teaching, these studies demonstrate the efficacy of techniques designed to enhance faculty teach
244 NAR1 improved CTL survival and increased the efficacy of the chimeric antigen receptor T cell transfe
248 authors sought to investigate the safety and efficacy of the different anticoagulants for treating HI
249 ties of EMPIS suggest that information about efficacy of the early immune response is fed back to the
251 is study demonstrates for the first time the efficacy of the HMP Airdrive system to protect liver gra
252 t this assumption, changes in the protective efficacy of the immune response to B. burgdorferi surfac
253 rther studies are necessary to determine the efficacy of the intervention as part of a multi-componen
258 We aimed to assess the long-term safety and efficacy of the proprotein convertase subtilisin/kexin t
260 trials, taken together with the demonstrated efficacy of the serotonin reuptake inhibitors for childh
262 y vector for a GLP-1 analogue and assess the efficacy of the therapeutic in improving host glucose, l
267 genetic heterogeneity of HCV has limited the efficacy of these agents and mutations lead to resistanc
271 s network meta-analysis aimed to compare the efficacy of these drugs and their combinations regarding
275 targeting moiety for L-ALD, the therapeutic efficacy of this therapy can be increased in alphavbeta6
278 we demonstrate that the antidepressant-like efficacy of three unique drugs, with reported rapid onse
279 ribute to better interpreting the off-target efficacy of TKIs in tumors and to envisaging strategies
280 AL) Strategy aimed to assess the comparative efficacy of tofacitinib monotherapy, tofacitinib plus me
281 To review the published literature on the efficacy of topical atropine for the prevention of myopi
286 is little evidence concerning the safety and efficacy of treating individuals with multiple food (mul
287 method for oxygen generation to enhance the efficacy of treatments that depend on the presence of ox
290 ylation of T387 of U-STAT2 might enhance the efficacy of type I interferons in many different clinica
291 ith the final aim of testing the therapeutic efficacy of UCB in MPS-I mice transplanted at birth, we
292 idly emerging as technologies to improve the efficacy of vaccines against infectious disease and immu
297 objective of this study was to evaluate the efficacy of Viscocanalostomy/Phacoviscocanalostomy (VC/P
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