ライフサイエンスコーパス: efficacy

1 t and how CAR T cells can be further engineered to maintain efficacy.

2 cally whether systemic drug exposure is crucial for in vivo efficacy.

3 roides spp morphotypes and those without these morphotypes (efficacy 68.62% vs 76.72%; pinteraction=0.652); or between th

4 LY3023414 demonstrates efficacy against EAC in a preclinical model, establishing the

5 GBCAs have shown efficacy and are safe to use with most patients; however, som

6 To compare the efficacy and safety of 2 sclerosants used to treat reticular

7 ts from recent studies strengthen the evidence base for the efficacy and safety of sublingual immunotherapy in patients w

8 , treatment efficacy is generally modest and differences in efficacy between antidepressant therapies are small.

9 onal groups had variable effects on metabolic stability and efficacy, but the most effective members of this series also

10 ng that ETO-curcumin may provide superior anti-inflammatory efficacy compared to standard curcumin.

11 a similar potency (pEC50 values between 9.53 and 9.78) and efficacy (Emax values between 130 and 160%).

12 The primary efficacy end point was a composite of adjudicated cardiovascu

13 nancies) occurred in settings with near-perfect SP curative efficacy (>99%) based on the most recent estimates of resista

14 inhibitor displaying excellent pharmacokinetic profile and efficacy in a human PTEN-deficient LNCaP prostate carcinoma x

15 iched with drugs having published evidence of antiepileptic efficacy in animal models than expected by chance (P-value <0

16 garding whether there may, or may not, have been protective efficacy in the RV144 vaccine trial have important societal i

17 the RNA structure in MYB33 correlated with strong silencing efficacy; introducing mutations to disrupt either SL attenuat

18 en evaluated according to aggregate measurements, treatment efficacy is generally modest and differences in efficacy betw

19 trial in which the first cohort assessed for the safety and efficacy of 12 weeks of sofosbuvir plus ribavirin for the tre

20 o6840.75 (95% CI 2545-2759) per QALY gained for a treatment efficacy of 20% and euro4243 per QALY gained for treatment ef

21 efficacy of 20% and euro4243 per QALY gained for treatment efficacy of 50%.

22 This randomized controlled trial examined the efficacy of a novel gaze-contingent music reward therapy for

23 The purpose of the current study is to determine the efficacy of a PI3K/mTOR dual inhibitor, LY3023414, on establi

24 Efforts to improve the efficacy of adoptive T-cell therapies and immune checkpoint t

25 Moreover, this conversion significantly increased the efficacy of anti-PD-1 checkpoint blockade.

26 ermore, PFT-mu administration did not impair the anticancer efficacy of cisplatin and radiotherapy in tumor-bearing mice.

27 A mathematical framework is devised to allow the efficacy of different candidates to be directly compared and

28 Antiallodynic efficacy of LY2828360 was absent in CB2 knockout (KO) mice.

29 tudy polio pathogenesis, candidate antiviral drugs, and the efficacy of new vaccines.

30 Moreover, the study demonstrates the efficacy of non-viral TUS-based hSef-b gene delivery approach

31 We hypothesized that MUC4 modulates corticosteroid efficacy of patients with CRSwNP.

32 te Th cell responses and to determine the immunosuppressive efficacy of RASF.

33 deline found no statistically significant difference in the efficacy of second-generation antidepressants (SGAs) versus m

34 y index (DAI) dose-dependently, while the anti-inflammatory efficacy of standard curcumin remained constant, suggesting t

35 We aimed to evaluate the efficacy of the parenteral (intravenous or intramuscular) ond

36 Uncontrolled studies have suggested efficacy of the proteasome inhibitor bortezomib, but no syste

37 how this virus-host interaction can be employed to enhance efficacy of this vector system.

38 Here, we demonstrate that the antidepressant-like efficacy of three unique drugs, with reported rapid onset ant

39 To review the published literature on the efficacy of topical atropine for the prevention of myopic pro

40 l as an in situ method for oxygen generation to enhance the efficacy of treatments that depend on the presence of oxygen

41 tabase as either having published evidence of antiepileptic efficacy or lacking such evidence, we demonstrated that our s

42 month death or dependency (modified Rankin Scale (mRs) >/=3;efficacy outcome), in patients with acute ICH randomised to e

43 7 and its validated bioluminescent strains for preservative efficacy tests using benzalkonium chloride (BKC).

44 inase inhibitor (CHMFL-BTK-11) which exerted its inhibitory efficacy through a covalent bond with BTK Cys481.

45 a viruses influenced HAI-specific antibodies and protective efficacy using a broadly protective vaccine candidate.

46 infection to explore the possibility of extracting NAI drug efficacy using only the observed viral titer decay rates seen

47 Efficacy was estimated from published studies and incorporate

48 PrEP efficacy was not significantly different between women with d

49 Potential moderators of efficacy were analyzed by meta-regression.

50 ntroducing mutations to disrupt either SL attenuated miR159 efficacy, while introducing complementary mutations to restor