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1 elate directly with an impact on Pgp-derived efflux.
2 amyloid precursor protein to facilitate iron efflux.
3 rescence specifically in HSCs because of dye efflux.
4 mulation, induced by the inhibition of auxin efflux.
5 hanced mitochondrial Na(+) uptake and Ca(2+) efflux.
6 Gbetagamma interacts with DAT to promote DA efflux.
7 enerate sufficient Fe(II) to suppress Cr(VI) efflux.
8 oward select xenobiotics by triggering their efflux.
9 d protection is the result of enhanced water efflux.
10 s exist for controlling lysosomal amino acid efflux.
11 hanistic insights into antibacterial peptide efflux.
12 facilitate efflux of the plant hormone auxin efflux.
13 te, which may facilitate efficient multidrug efflux.
14 orption and promoting macrophage cholesterol efflux.
15 m measurements of the intrinsic rate of acid efflux.
16 potassium (K(+)) channels and resultant K(+) efflux.
17 MCs in the lesions, and impaired cholesterol efflux.
18 howed increased channel activity and Mal(2-) efflux.
19 gger the exchange mode, leading to substrate efflux.
20 t with APOE's role in regulating cholesterol efflux.
21 is Xpr1 deficiency significantly affected Pi efflux.
22 oss of TSPO resulted in impaired cholesterol efflux.
23 and nutrient retention, but no effect on CO2 efflux.
24 drug delivery agents to evade P-gp-dependent efflux.
26 (FADS1), cellular cholesterol uptake (LDLR), efflux (ABCA1 and ABCG1), and inflammation (DHCR24).
30 sequent edema can hinder cerebrospinal fluid efflux and can lead to locally increased pressures in th
31 ncreasing OsALMT4 expression affected malate efflux and compartmentation within the tissues, which in
32 ty, we estimated that most of the litter CO2 efflux and decay occurring in the dry season was due to
35 everal signaling events, including cytosolic efflux and influx of select ions, have been suggested.
38 inflammasome activation, which involved K(+) efflux and M1 protein internalization by clathrin-mediat
42 te macrophage M2 polarization or cholesterol efflux, and thereby MafB mediates their beneficial effec
44 ticipants who were in the higher cholesterol efflux/apoA-I presented significantly higher disposition
45 subjects who were in the higher cholesterol efflux/apoA-I quartile compared to subjects in the lowes
46 tes was analysed by quartiles of cholesterol efflux/apoA-I, incidence of T2DM was reduced by 54% in s
47 ion of the purinergic receptor P2X7 and K(+) efflux, apoptosis-associated speck-like protein with a C
48 ted cholesterol endocytosis, and cholesterol efflux are all essential to NCEH-1-mediated neuroprotect
49 nducible factor (HIF) that increases lactate efflux as a result of enhanced glycolysis, but it also e
53 -) diminishes the inward tail current (Cl(-) efflux) at a membrane potential of -100 mV due to the lo
55 uxin are regulated by facilitated uptake and efflux, but detailed molecular understanding of the carr
56 ession, and increased macrophage cholesterol efflux by inducing ATP-binding cassette subfamily A memb
57 nown crystal structures and show that Ca(2+) efflux by LMCA1 is rate-limited by phosphoenzyme formati
58 In neuronal cultures lithium attenuates iron efflux by lowering tau protein that traffics amyloid pre
59 nvasive infection, we demonstrated that iron efflux by PmtA is critical for bacterial survival during
62 tatin (20 mg/day) did not change cholesterol efflux capacity (average percentage change -1.5%, 95% CI
63 ood samples were drawn to assess cholesterol efflux capacity (CEC) and changes in gene expression in
64 ggest that CD4(+)CD161(+) T cells with rapid efflux capacity contribute to the maintenance of viral-s
66 we investigated whether the HDL cholesterol efflux capacity is predictive for cardiovascular risk.
71 ression analyses, we found no association of efflux capacity with the combined primary end point (haz
72 erol levels, apolipoprotein A-I, cholesterol efflux capacity, and HDL particle number were assessed a
73 indices of HDL quality, such as cholesterol efflux capacity, and HDL quantity, such as HDL particle
74 to be largely determined by its cholesterol efflux capacity, which was shown to inversely correlate
75 isation, requires simultaneous modulation of efflux carrier level and polarity; and (3) multiple patt
77 ity; and (3) multiple patterns of influx and efflux carriers for maintaining an auxin pattern do not
79 nvolve PIN-FORMED (PIN)-type plasma membrane efflux carriers that generate subcellular auxin gradient
87 a subset of memory CD4(+) T cells capable of effluxing cellular toxins, including rhodamine (Rho), th
89 nt activity (-35%) and a reduced capacity to efflux cholesterol (-60%) compared to NC-HDL (p < 0.05).
91 sing element that drives the assembly of the efflux complex ahead of the transcription activation of
92 living Escherichia coli cells the tripartite efflux complex CusCBA of the resistance-nodulation-divis
96 AT blocked the ability of mSIRK to induce DA efflux, consistent with a direct interaction of Gbetagam
98 evealed that M2 polarization and cholesterol efflux do not necessarily represent inter-dependent even
99 to affect SLC30A9's highly conserved cation efflux domain, putatively disrupting its transmembrane h
100 In brief, ALMT4 likely mediates Mal(2-) efflux during ABA-induced stomatal closure and its activ
103 al neurons, not astrocytes; mediates HCO3(-) efflux) enhances intracellular pH (pHi ) recovery (decre
105 y', in the presynaptic cytosol revealed acid efflux following nerve activity to be greater than that
106 ing and root trenching and measured soil CO2 efflux for over 1 yr in longleaf pine (Pinus palustris),
108 , vascular tone in aortic rings, cholesterol efflux from macrophages, and expression of SMC phenotypi
110 endoplasmic reticulum arises through Ca(2+) efflux from mitochondria during brief openings of the mi
111 int to a primary role of MtMATE67 in citrate efflux from nodule cells in response to an Fe signal.
112 e hypothesize that by allowing dicarboxylate efflux from the matrix, PTP opening during reperfusion m
115 es a pronounced, delayed enhancement of K(+) efflux, generating an optimal intracellular environment
120 demonstrate the essential nature of mCa(2+) efflux in cellular function and suggest that augmenting
122 oA-I]-binding protein)-regulated cholesterol efflux in endothelial cells controls zebra fish embryoni
124 Both fluoxetine and thioridazine inhibited efflux in P. mirabilis, and molecular modelling predicte
127 both JJ-3-42 and lorcaserin reduced dopamine efflux in the infralimbic cortex, while only JJ-3-42 dec
129 n variants on SLC22A1-mediated acylcarnitine efflux in vitro, explaining their association with serum
130 the contribution of exosomes to active drug efflux increased with drug concentration and exceeded th
131 sk factors for AMD, although how cholesterol efflux influences accumulation of this lipid in sub-RPE
132 pase-1 inhibition, NLRP3 knockdown, and K(+) efflux inhibition and were not observed with other non-a
135 study evaluated whether baseline cholesterol efflux is associated with future development of type 2 d
137 us expression system indicate that this acid efflux is mediated by conventional plasmamembrane acid t
143 function and suggest that augmenting mCa(2+) efflux may be a viable therapeutic strategy in disease.
144 clude metallopeptidases, multidrug-resistant efflux (MDR) pumps, TonB-dependent receptors and many pr
145 r endocytosis or exocytosis revealed an acid efflux mechanism reliant upon synaptic vesicle exocytosi
146 ve been resolved, shedding some light on the efflux mechanism underlying this intriguing system.
152 both NLRP3 depletion and inhibition of K(+) efflux mitigated abacavir-induced mitochondrial reactive
155 c22a1, we uncovered a role of SLC22A1 in the efflux of acylcarnitines from the liver to the circulati
156 ciated with transmembrane proteins mediating efflux of administered drugs, thereby keeping their intr
157 adaptor protein and TolC exit duct to drive efflux of antibiotics and enterotoxin STII out of the ba
158 Pannexin-1 (Panx1) channels mediate the efflux of ATP and AMP from cancer cells in response to i
160 and inhibited DHPR and SERCA, inducing a net efflux of Ca(2+) from loaded microsomes, whereas BPA exh
162 wn, in vitro, to participate in the cellular efflux of desmosterol and amyloid-beta peptide (Abeta).
165 l vacuoles, specifically of K(+) and Mal(2-) Efflux of Mal(2-) from the vacuole is required for stoma
166 ition of mTOR strongly reduced the lysosomal efflux of most essential amino acids, converting the lys
170 Our model considers the cellular uptake and efflux of PFOA via both passive diffusion and transport
171 ins (NBDs) to power the energetically uphill efflux of substrates by a dedicated transmembrane domain
172 ing in the inner membrane resulting in rapid efflux of succinate/fumarate and other dicarboxylates ca
173 ially facilitate phloem loading by enhancing efflux of symplasmic Suc for subsequent active uptake in
180 lance equations to track C influxes into and effluxes out of individual pools in earth system models
181 ell death involves interplay between ATP/AMP efflux pathways and different cell-autonomous ectonucleo
184 e genes, arsP that encodes the ArsP MAs(III) efflux permease, and arsH encoding the ArsH MAs(III) oxi
186 uding rhodamine (Rho), through the multidrug efflux protein MDR1 (also known as P-glycoprotein and AB
187 strain expressing the tetracycline-specific efflux pump (TetA) compared to the isogenic control.
188 ction proteins, VEGF-dependent permeability, efflux pump activity and receptor-mediated transcytosis
189 nesis identified the importance of the AcrAB efflux pump and lipopolysaccharide O-antigen synthesis f
190 us is recognised for its ability to modulate efflux pump and porin expression via two encoded transcr
192 ucleotide polymorphisms (SNPs) as well as an efflux pump cmeB mutation that conferred modest resistan
195 of the Escherichia coli AcrAB-TolC multidrug efflux pump in resting and drug transport states, reveal
198 ant efflux pump of Staphylococcus aureus, an efflux pump inhibitors (EPIs) library was used for ligan
199 ine biofilms, highlighting the potential for efflux pump inhibitors (EPIs) to control catheter blocka
201 ancer types, the functional activity of this efflux pump is more difficult to elucidate, especially a
202 e report that AcrAB-TolC, the main multidrug efflux pump of Escherichia coli, exhibits a strong parti
205 (formerly YdfM) serves as the primary Mn(II) efflux pump with MneS (formerly YeaB) playing a secondar
206 code a copper binding chaperone and a copper efflux pump, but in some the chaperone encoding gene has
214 ell lines with activated P-glycoprotein drug efflux pumps compared to drug-sensitive parent cells, de
218 on independently within the trimer.Multidrug efflux pumps significantly contribute for bacteria resis
219 ng pharmacokinetic variability, induction of efflux pumps that transport the drug out of cells, and s
220 ight the importance of performing studies of efflux pumps under near-physiological conditions, in a l
222 ing multidrug-resistance mechanisms, such as efflux pumps, are under development and hold promise for
223 st of the AR genes were characterized as ABC efflux pumps, RND efflux pumps, and tetracycline MFS eff
232 As-hyperaccumulator Pteris vittata arsenite efflux (PvACR3), on As tolerance, accumulation, transloc
235 ion was observed between temocillin MICs and efflux rate of N-phenyl-1-naphthylamine (MexAB-OprM fluo
236 entrations increased growing-season soil CO2 efflux rates by increasing annual aboveground net primar
238 improved Caco-2 permeability, reduced Caco-2 efflux, reduced hERG PC activity, and increased selectiv
239 agalactiae (PDB 3KKC) is the bona fide zinc efflux regulator SczA, and binds two zinc ions per proto
240 e the outer membrane, improved inhibition of efflux relative to 1, and potentiation of the activity o
242 losteric inhibition of DNA binding by the Zn efflux repressor CzrA (chromosomal zinc-regulated repres
243 sly shown that efficient PIN1-mediated auxin efflux requires activation through phosphorylation at th
252 otent at inhibiting AMPH-stimulated dopamine efflux than [(3)H]dopamine uptake through the dopamine t
253 nnels and activates H(+) -ATPase proton pump efflux that dissociates periplasmic AGP-Ca(2+) resulting
256 ding/activating peptide, mSIRK, increases DA efflux through DAT in heterologous cells and primary dop
257 t TSPO specific ligands promoted cholesterol efflux to acceptor (apo)lipoprotein and human serum, whi
258 s identified to support a role of macrophage efflux to draining lymph nodes following treatment with
261 As(V) reduction in roots, decreased As(III) efflux to the external medium and markedly increased As
263 c strategies to inhibit ABCB1/ABCG2-mediated efflux transport at the BBB have been successfully devel
265 tes the blood-brain barrier (BBB) because of efflux transport by P-glycoprotein (ABCB1) and breast ca
266 duced inhibition of the multidrug-resistance efflux transporter ABCB1, which is frequently expressed
267 an Arabidopsis (Arabidopsis thaliana) boron efflux transporter displayed boron deficiency phenotypes
268 ere we utilized FrvA, a high-affinity Fe(2+) efflux transporter from Listeria monocytogenes, as an in
270 increases the expression and activity of the efflux transporter P-glycoprotein (P-gp) encoded by ABCB
271 oupled conformational cycle of the mouse ABC efflux transporter P-glycoprotein (Pgp; also known as AB
272 ux transporters-Arabidopsis PM-located auxin efflux transporter PIN-formed 1 (PIN1) and Arabidopsis P
273 ed 1 (PIN1) and Arabidopsis PM-located auxin efflux transporter PIN-formed 3 (PIN3)-to the PM, thereb
274 Finally, both Arabidopsis thaliana auxin efflux transporter pin1 and influx transporter lax2 muta
276 SLC30A10, a cell-surface-localized manganese efflux transporter, cause a heritable manganese metaboli
277 lls stably expressing specific uptake and/or efflux transporters revealed that OATP1B1, OATP1B3, and
278 lthough doxorubicin is a known substrate for efflux transporters such as P-glycoprotein (P-gp; MDR1,
279 s/regulators, soluble chaperones, and influx/efflux transporters that control the Cu(+) levels in P.
280 s, restrictive barrier formation, influx and efflux transporters with relevance to understanding peri
281 ellular drug concentrations mediated by drug efflux transporters, and permeability barriers associate
282 affect transport activity of two other major efflux transporters, multidrug resistance protein 2 and
283 expression alters the trafficking of 2 auxin efflux transporters-Arabidopsis PM-located auxin efflux
284 mbly allows the bacterial cell for efficient efflux upon cellular demand while still maintaining peri
286 greater influence during the wet season when efflux was high than during the dry season when efflux w
287 s across the Mediterranean Basin, litter CO2 efflux was largely explained by litter moisture driving
291 In vitro, radiotracer incorporation and efflux was similar with no effect on cell viability, fun
293 Given the role of AcrAB-TolC in multi-drug efflux we suggest that CsrA is a potential drug target.
294 antibiotic target alteration and antibiotic efflux were the dominant resistance mechanism categories
295 r techniques used to measure day respiratory efflux were valid and whether day respiration responded
297 C1-R agonists similarly promoted cholesterol efflux, which is a counterregulatory mechanism against f
299 ecreases methamphetamine-stimulated dopamine efflux without affecting basal dopamine neurotransmissio
300 istency with C. albicans nomenclature) could efflux xenobiotics such as berberine, rhodamine 123, and
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