ライフサイエンスコーパス: effort

1 neutralizing responses were crucial in this effort.

2 tools, which spare us considerable time and effort.

3 ies of marine rock or time-variable sampling effort.

4 oductive output up to a high level of annual effort.

5 as model experimental systems sustained this effort.

6 easurements than any previous classification effort.

7 s cross-analysis of these studies is a major effort.

8 e sea level rise upon which to base planning efforts.

9 otypes across diagnoses may aid gene-finding efforts.

10 as a target for intervention in eradication efforts.

11 h assemblages and to help focus conservation efforts.

12 uide communication, prevention, and planning efforts.

13 s across hosts, despite large-scale sampling efforts.

14 ssible chemical space and reducing synthetic efforts.

15 ls and the success of coral reef restoration efforts.

16 of being neutralized by current vaccination efforts.

17 created to inform ongoing ASTS organ access efforts.

18 ications is important to quality improvement efforts.

19 g, chemical testing and pollution prevention efforts.

20 orld impact for ongoing global food security efforts.

21 m targeted early intervention and prevention efforts.

22 re serotype data, are relevant to prevention efforts.

23 needed to fill these gaps, and prioritizing efforts.

24 ts, and a system for grading quality of test efforts.

25 nities, potentially improving dengue control efforts.

26 d (1, 4, 8, 12, or 15 apples) was 'worth the effort' (10%, 27.5%, 45%, 62.5%, and 80% of maximal volu

27 ehension difficulty, but also with cognitive effort across a wide range of nonlinguistic tasks in a d

28 Few system-wide efforts affecting multiple hospital emergency department

29 including microcephaly, has prompted intense efforts aimed at the development of new and specific dia

30 Existing efforts aimed to improve the sustainability of seafood p

31 These efforts also determined that many of these small molecul

32 Despite ongoing efforts, an efficient tool for accurate estimation of AA

33 in less than a year with relatively minimal effort and investment.

34 enefit valuation across different domains of effort and provide insight into the multidimensional nat

35 utational fMRI, we show parallel encoding of effort and reward prediction errors (PEs) within distinc

36 k are easily incorporated into concurrent EM efforts and broaden the application opportunities and ac

37 rovides a comprehensive overview of clinical efforts and outcome of microneedle based systems.

38 Despite great efforts and significant progress, the molecular details

39 ecific structure-activity relationship (SAR) effort, and specific binding assessment using a LC-MS/MS

40 e measured arterial blood gases, inspiratory effort, and work of breathing by esophageal pressure swi

41 f the complexities of RAS that thwarted past efforts, and armed with new technologies and directions,

42 cs, and transcriptomics into future research efforts; and build molecular annotations of network pert

43 In the conclusion, current commercial efforts are briefly considered.

44 Considerable scientific and technological efforts are currently being made towards the development

45 Current efforts are directed to reducing the gut dysbiosis and i

46 Such efforts are impeded by the lack of a physiologically rel

47 However, further efforts are necessary to address the high rate of primar

48 INTERPRETATION: Increased efforts are needed, especially in developing countries,

49 Efforts are nevertheless made to maximize the metabolome

50 Efforts are now underway to develop DOACs that inhibit c

51 These efforts are ongoing as new projects are developed and th

52 Maximal pressure injury prevention efforts are particularly important among critical-care p

53 Efforts are under way to improve the efficacy of subunit

54 d on the presence of signs and symptoms, but efforts are underway to develop inexpensive, reliable, p

55 er than relying on natural viral properties, efforts are underway to engineer viruses to respond to e

56 feature is persistent mood instability, and efforts are underway to understand its mechanisms and it

57 To date, significant research efforts are underway to understand the spread and the un

58 physiological variables, including cognitive effort, arousal, attention, and even learning.

59 the basis of this potential, we targeted our efforts at identifying potent inhibitors of FXIa with a

60 We discuss the need for additional research efforts beyond standard biodiversity monitoring to recon

61 y, eradicating extreme poverty increases the effort by 2.8% whereas bringing everybody to at least $2

62 This supplement focuses on efforts by global partners to successfully launch polio

63 Efforts by RANO have been widely accepted and are increa

64 hepatocytes is associated with regenerative efforts characterized by continual hepatocyte proliferat

65 despite more than three decades of research effort, clinically effective anti-RAS therapies have rem

66 to achieve each of two different goals; a No Effort condition in which the adult achieved the goals e

67 were assigned to one of three conditions: an Effort condition in which they saw an adult try repeated

68 stered experiments (N = 262), infants in the Effort condition made more attempts to achieve the goal

69 limited to alkyl and aryl groups, additional efforts culminated in the expansion of the scope of the

70 ures including maternal vaccines are ongoing efforts designed to reduce the burden of neonatal sepsis

71 tes are becoming a primary focus of research efforts due to their association with progressive glomer

72 ne setting for initiating suicide prevention efforts, ED-initiated suicide prevention interventions r

73 A multifaceted national effort employed novel strategies to recruit a diverse co

74 ical effort exertion by computing subjective effort equivalents.

75 sm, examining both the limitations to mental effort exertion and how we manage those limited cognitiv

76 ) plays in motivating cognitive and physical effort exertion by computing subjective effort equivalen

77 These efforts expand our understanding and ability to interrog

78 d reward sensitivity were measured using the Effort Expenditure for Rewards Task (EEfRT), in which mo

79 espite numerous theoretical and experimental efforts, few examples have been reported.

80 ions of new infections annually, and current efforts focus on understanding cellular immunity for tar

81 ions for TLD have been advanced, with recent efforts focused on recombination proteins and replicatio

82 making it possible for him to devote all his efforts following his discovery of dibenzo-18-crown-6 un

83 anipulated nutritional shortfall and begging effort for a period of 10 days.

84 We evaluate important modeling efforts for establishing how crosstalk between auxin, cy

85 Here, we review the status of these clinical efforts for several significant retinal diseases, descri

86 approaches that can both paradoxically shift effort from low-cost workers to much costlier profession

87 Substantial efforts had been made to identify significantly mutated

88 While tremendous effort has been devoted to identifying molecular charact

89 ct formation from CO2, where the majority of efforts has been to use oxidized copper-based materials.

90 or pharmacokinetic properties, and how these efforts have been critical to the discovery, design, and

91 Most efforts have been focused on extracting the kinetic ener

92 ch, significant anti-cancer drug development efforts have been focused on targeting it, most notably

93 Efforts have been made to enhance the sensory quality of

94 cause it is usually diagnosed late, and many efforts have been made to improve prevention, early dete

95 Therefore, many efforts have been proposed to modify the antibacterial f

96 SMA therapeutics development efforts have focused on identifying strategies to increa

97 Increasing efforts have focused on pharmacological hypothermia as a

98 Particular efforts have focused on the formation of the ventral fur

99 Cancer genomics efforts have identified genes and regulatory elements dr

100 Recently, cancer genome sequencing efforts have identified recurrent Rheb Tyr35Asn mutation

101 The NIMH supported efforts have led to a vast increase in the amount of gen

102 Several large-scale efforts have systematically catalogued protein-protein i

103 Large-scale transcriptome sequencing efforts have vastly expanded the catalog of long non-cod

104 s Task (EEfRT), in which motivation for high-effort/high-reward trials vs low-effort/low-reward trial

105 Despite this effort, however, pharmacological options for ARDS remain

106 A focused screening and lead optimization effort identified 4b (GS-5734) with anti-EBOV EC50 = 86

107 hroughput screen and subsequent optimization effort identified the first orally bioavailable and CNS

108 inks to altered PNS regulation during mental effort in older adults, and that the compensatory proces

109 lection for unrelated targets to invest more effort in resisting eviction.

110 imize monetary rewards and minimize physical efforts in a probabilistic instrumental learning task.

111 hospital pathogens, which has led to renewed efforts in antibiotic drug discovery.

112 and review the examples resulting from these efforts in both inhibiting and stabilizing specific 14-3

113 ons, illustrating a principle predicted from efforts in de novo protein design.

114 This work will enable future efforts in developing highly efficient biomimetic assays

115 on, which is key to direct lead optimization efforts in drug discovery.

116 sures, together with continued international efforts in education and training in the management of f

117 aria exposure and evaluating malaria control efforts in high endemic area.

118 Despite tremendous efforts in identifying response-associated genes in larg

119 candidate target genes for future treatment efforts in ovarian cancer.

120 road-based, global strategy, such as greater efforts in prevention, as well as better screening and m

121 on observed suggests vascular redistribution efforts in response to challenges in the perinatal perio

122 Intensive recent efforts in the development of new reactions based on C-H

123 es assessing large-scale quality improvement efforts in the ICU, impact of safety culture on patient

124 of tremendous synthesis and characterization efforts in the past two decades.

125 Successful mitigation efforts in the Red Deer region will need to focus on the

126 We extended previous efforts in three dimensions, examining a more comprehens

127 kforce capacity to support polio eradication efforts, including national STOP programs.

128 ed to paradigm-changing precision prevention efforts, including: tumor testing for mismatch repair (M

129 Greater search effort increases the probability of rediscovery in large

130 Much effort is underway to develop strategies to reduce Abeta

131 concurrent appetitive (money) and aversive (effort) learning task.

132 After familiarization with 5 effort levels, participants made a series of accept/reje

133 on for high-effort/high-reward trials vs low-effort/low-reward trials are manipulated by variations i

134 Our findings suggest enhanced efforts may be warranted to screen all sexually active H

135 Despite increased research effort, much remains unknown about these phenomena, espe

136 This effort must involve natural history, ecology, and evolut

137 Efforts need to be intensified along the food chain to r

138 However, despite substantial efforts, no generally applicable computational method ha

139 Such rare situation calls for realistic efforts of de-extinction through selective breeding with

140 In this article, we report the efforts of ICHOM's working group in colorectal cancer.

141 requires novel approaches and the integrated efforts of multiple disciplines to be a fruitful strateg

142 To date, this study is the first deep WGS effort on children with JIA and provides useful genetic

143 Focusing intervention efforts on LTACHs is potentially a highly efficient stra

144 In particular, we focused our efforts on the identification of small molecules that co

145 In the last several decades, efforts on understanding and controlling self-assembly o

146 ocus on a new pathway instead of making huge effort or investment in designing high-capacity but expe

147 he focus of multiple independent development efforts over an extended period.

148 rs (PEs) within distinct brain regions, with effort PEs expressed in dorsomedial prefrontal cortex an

149 Are the current administrative efforts reaching the right audience and what changes awa

150 European starling nestlings and the begging Effort required to obtain food during early development.

151 Future efforts should consider the dynamic nature of whole-plan

152 Future efforts should focus on how to exploit this knowledge to

153 a framework for how future genome sequencing efforts should incorporate transcriptomic and proteomic

154 Quality improvement efforts should shift focus from individual measures to d

155 pic differentiation and has defied culturing efforts so far.

156 Conservation efforts strive to protect significant swaths of terrestr

157 ric cancer by human cancer genome sequencing efforts, suggesting both pro- and anti-neoplastic roles.

158 biological systems is often a collaborative effort that may be detrimental to the producers.

159 Project encompasses a genus-level sequencing effort that represents a new type of model system driven

160 y areas for future research and conservation efforts: the continental shelf adjacent to east central

161 different contexts, and we appreciate their effort to assess whether the transmission of grooming st

162 In an effort to better understand the linkages between iron me

163 In an effort to broaden sequence recognition of DNA-targeted-s

164 commitment between two adults who join their effort to care for children-is a central contributor to

165 The review, is an effort to condense the recent research on l-Th highlight

166 Perspective, we propose a national concerted effort to create a Precancer Atlas (PCA), integrating mu

167 In an effort to delineate the temporal and spatial dynamics of

168 In an effort to determine the mechanism by which FMRP mediates

169 This evidence gave rise to a global effort to develop a new generation of therapeutics that

170 A sustained effort to develop and share diagnostic methods can suppo

171 Decades of effort to develop direct Ras inhibitors for clinical use

172 At present, there is an ongoing effort to develop methods to effectively quantify the ra

173 In an effort to develop synthetic materials that transduce mec

174 In an effort to disentangle hypha-associated virulence factor

175 s are shifting toward value-based care in an effort to drive better outcomes in the setting of rising

176 The Personal Genome Project (PGP) is an effort to enroll many participants to create an open-acc

177 he overall approach of this work provides an effort to fabricated membranes with high water flux and

178 In an effort to find new and safer treatments for osteoporosis

179 In an effort to identify new antidiabetic agents, we have disc

180 This decade-long effort to increase student participation in collections

181 stions regarding how best to allocate mental effort to minimize those costs and maximize the attendan

182 er or not to engage in cognitive or physical effort to obtain rewards.

183 ceae (CP-CRE) is an important element of the effort to prevent and contain the spread of these pathog

184 The present work is a novel computational effort to provide insight on the mechanisms of cavitatio

185 Although there has been a sustained effort to reconstruct the dynamics of the phosphorus cyc

186 In an effort to regulate physician conflicts of interest, some

187 Our study is the first effort to rely on Bayesian model calibration and synthes

188 The effort to simplify diagnosis could be overcome by the ri

189 phasize or forsake their core missions in an effort to survive.

190 ptomic analysis of all three organisms in an effort to understand the elusive properties of Pseudozym

191 This was part of a larger effort to update existing clinical practice guidelines o

192 ting antibiotics is an important strategy in efforts to address the escalating antimicrobial resistan

193 This has hindered efforts to analyze fine-root trait variation and link it

194 Approaches range from drug discovery efforts to big-data methods and direct-to-consumer (DTC)

195 These data support ongoing efforts to centralize care for patients undergoing PD.

196 Despite efforts to characterize the different aspects of musical

197 Recently, the global efforts to collect subjects with Mendelian disorders, to

198 Recent efforts to combat increasing greenhouse gas emissions in

199 Despite efforts to combine plasmonic and catalytic metals, the p

200 nal medicine, there have been relatively few efforts to comprehensively and consistently analyze the

201 s, fueling PsychENCODE and other large-scale efforts to comprehensively map neuronal and nonneuronal

202 ding increases over time could inform policy efforts to contain future spending growth.

203 thereby placing silicon at the forefront of efforts to create a solid-state quantum processor.

204 gh-priority bacterial pathogens targeted for efforts to decrease transmissions and infections in heal

205 In our efforts to define a cancer dependency map, we performed

206 Our work will further efforts to define and deploy useful microbes to enhance

207 brain tissue during development has hampered efforts to define molecular networks controlling this pr

208 These competing effects frustrate efforts to design and engineer stable, active enzymes wi

209 nditions and there have been active research efforts to develop high-throughput platforms to mechanic

210 ation and fragment-based lead discovery with efforts to develop new antimicrobials for mycobacterial

211 spected impact on hematopoiesis; (4) ongoing efforts to develop new models to study niche-leukemic ce

212 in controlling disease processes has spurred efforts to develop pharmaceutical regulators of their ac

213 d diseases and declining function, prompting efforts to eliminate them.

214 Current efforts to enhance RTS,S/AS01E efficacy would benefit fr

215 This property may be especially important to efforts to eradicate latently infected cells.

216 cle and a key intervention target of ongoing efforts to eradicate malaria.

217 omone will also be a crucial tool in ongoing efforts to eradicate the beetle from regions of the worl

218 ca between 2013 and 2016 resulted in intense efforts to evaluate the efficacy of several specific cou

219 Efforts to exploit aneuploidy tolerance mechanisms and t

220 In our efforts to generate a new medicine for liver fibrosis, w

221 stant to frontline therapeutics has prompted efforts to identify and validate agents with novel mecha

222 cinoma (PDA) is a deadly cancer that resists efforts to identify better chemotherapeutics.

223 Efforts to identify driver mutations in cancer have larg

224 Efforts to identify pharmaceuticals to treat heritable m

225 Herein, we describe our efforts to identify reversible inhibitors of LSD1 from a

226 Our findings suggest that the ongoing efforts to improve crop photosynthesis by integrating co

227 Efforts to improve health outcomes for patients with CKD

228 derstanding of human biology and advance our efforts to improve health.

229 ion efficacy is needed to inform therapeutic efforts to improve it.

230 of this differential regulation will enhance efforts to improve oilseed rape productivity and quality

231 morbid condition that warrants attention in efforts to improve pretransplant screening and managemen

232 ountries is another reason to step up global efforts to improve prevention and care for diabetes.

233 Efforts to improve the efficacy of adoptive T-cell thera

234 wth and defense will help lignin engineering efforts to improve the production of biofuels and aromat

235 Targeted efforts to improve transplant center participation in pa

236 for when considering the monetary impact of efforts to improve water quality.

237 e care cascade by race is imperative, as are efforts to increase serodiscussion and strengthen relati

238 Efforts to increase the dissemination and implementation

239 sional (2D) materials has inspired worldwide efforts to integrate distinct 2D materials into van der

240 However, there is a long history of efforts to investigate the relationship between antibiot

241 species, but data patchiness has challenged efforts to link population dynamics to key drivers.

242 Efforts to manipulate locus-specific histone acetylation

243 Efforts to minimize nonexistent risks are futile and a m

244 Efforts to model DUX4 myopathy in mice have foundered ei

245 y tool to survey mussels and enhance current efforts to monitor and protect freshwater mussel biodive

246 ) sparked curiosity but necessitated further efforts to obtain appropriate reference genomes.

247 Efforts to optimize iron status should keep these findin

248 An emphasis is placed on describing research efforts to overcome the inherent weaknesses of peptide d

249 ottleneck in the demographic cycle of trees, efforts to predict the long-term effects of a changing c

250 Many efforts to prevent or treat these deficiencies are hampe

251 ict protection, new large-scale conservation efforts to protect intact forests are necessary to slow

252 In addition, efforts to realize long spin transport in single-crystal

253 mortality rates by race/ethnicity to inform efforts to reduce disparities in sepsis deaths.

254 Our analysis suggests that breeding efforts to reduce gs in legumes could increase WUEi by 1

255 These findings support efforts to reduce sugar consumption.

256 ational culture in the context of hospitals' efforts to reducing 30-day risk-standardized mortality a

257 However, recent efforts to relate a century of observed changes in U.S.

258 or the specific medical conditions hampering efforts to restore population levels.

259 amphibian conservation plans should include efforts to safeguard hundreds of direct-developing amphi

260 Efforts to standardize PET acquisition and reporting, in

261 As part of our efforts to target the 5-HT6 receptor, new benzimidazole-

262 scle regeneration could help inform research efforts to treat muscle diseases or improve muscle funct

263 tington's disease (HD) has promoted numerous efforts to uncover cellular pathways that lower levels o

264 In efforts to uncover the mechanism by which SLFN5 promotes

265 Large-scale efforts to understand biology and health have yielded ke

266 ent field of urban evolution brings together efforts to understand evolution in response to environme

267 nt and treat AD remain elusive despite major efforts to understand its basic biology and clinical pat

268 Despite concerted functional genomic efforts to understand the complex phenotype of ionizing

269 ite extensive experimental and computational efforts to understand the nature of the hierarchy of pro

270 c programs of gene expression and facilitate efforts to understand the roles of microglia in human br

271 The increasing efforts to use ingredients that are as natural as possib

272 tion and as a component of synthetic biology efforts to valorize previously underused aromatic compou

273 on by some naturally occurring compounds and efforts toward development of small molecules and biolog

274 ides a comprehensive review of the synthetic efforts toward each member of the natural product family

275 e men who performed surgical operations, the efforts toward group organization provided a means to pr

276 main limitation of this chemical series, and efforts toward its minimization are reported.

277 cost-effective tool for increasing parental efforts toward reducing children's physical growth defic

278 These data, however, have spurred efforts toward the discovery and development of improved

279 Major efforts toward the identification of chemical modulators

280 ansformation is of crucial importance to all efforts towards extending the species range of the techn

281 We then review recent efforts towards man-made dissipative assembly of structu

282 urthermore, the visual cue to engage maximum effort triggered an anticipatory widespread increase of

283 Our efforts uncover replication-dependent and -independent I

284 .2 billion compared with continuing Constant Effort up to 2050.

285 Concurrent with our in vivo optimization effort using 9, we further improved LLE as exemplified b

286 As expected, high peak effort was positively associated with lifetime reproduct

287 d devaluation by both cognitive and physical effort was subserved by a common network of areas, inclu

288 In this effort we propose a new laser wrapped graphene-Ag array

289 After accounting for reporting effort, we show that zoonotic EID risk is elevated in fo

290 nd provide insights for future public health efforts, we analyze the geospatial pattern of measles tr

291 through 2011) and after (2012 through 2014) efforts were made to decrease inappropriateness rates.

292 These efforts were recently transformed by advances in computi

293 ality, allowing the reduction of replication effort when call rate is high.

294 ecosystems to inform conservation and policy efforts where biological data are not available.

295 putation, in order to influence experimental efforts, which may in turn influence the outcome of cell

296 erations as well as gaps in current research efforts will be identified.

297 These efforts will contribute to a more complete understanding

298 Association of resuscitation efforts with survival and neurological outcomes from 201

299 ostics, integration of cross-species mapping efforts with the Mammalian Phenotype Ontology, an improv

300 These efforts would affect more individuals of more species du