ライフサイエンスコーパス: elastic fibre

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1 erus and skin, all of which contain abundant elastic fibres.

2 ctivity, indicating defective development of elastic fibres.

3 l role in the development and homeostasis of elastic fibres.

4 matrix, where it alters the architecture of elastic fibres.

5 stry shows reduced elastin deposition in the elastic fibres and fewer microfibrils in the dermis.

6 Although elastic fibres are known to be composed of microfibril p

7 When aiming to engineer suitable implants, elastic fibres are needed to allow adequate tissue renew

8 Here we show that the loss of Fibulin-5, an elastic fibre component, not only decreases tissue stiff

9 Aortas in Adamts-4-/- mice showed reduced elastic fibre destruction, versican degradation, macroph

10 It is believed that microfibrils regulate elastic fibre formation by guiding tropo-elastin deposit

11 m-binding glycoprotein that is essential for elastic fibre formation.

12 e disorder characterized by calcification of elastic fibres in skin, arteries and retina that results

13 ls, thereby acting to stabilize and organize elastic fibres in the skin, lung and vasculature.

14 Fibulin-5 interacts directly with elastic fibres in vitro, and serves as a ligand for cell

15 ing protein that localizes to the surface of elastic fibres in vivo.

16 ought to result when FBN1 mutations preclude elastic fibre maturation by disrupting microfibrillar as

17 nnective tissue and deposit the collagen and elastic fibres of the extracellular matrix (ECM).

18 egrin ligand, is an essential determinant of elastic fibre organization.

19 Extracellular elastic fibres provide mechanical elasticity to tissues

20 The formation of elastic fibres requires the assembly and crosslinking of

21 The elastic fibre system has a principal role in the structu

22 ne targeting exhibit a severely disorganized elastic fibre system throughout the body.

23 Thus, fibulin-5 may provide anchorage of elastic fibres to cells, thereby acting to stabilize and

24 a scaffold protein that organizes and links elastic fibres to cells.

25 with minimal spreading or to cause a pair of elastic fibres to coalesce.

26 lastinopathy owing to the disorganization of elastic fibres, with resulting loose skin, vascular abno

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