ライフサイエンスコーパス: elderly

1 LY burdens in children, adolescents, and the elderly.

2 memory decline in a larger sample of normal elderly.

3 F with preserved LV ejection fraction in the elderly.

4 16, NVTs constituted 72% of IPD cases in the elderly.

5 of current pediatric PCVs against IPD in the elderly.

6 ontributor to morbidity and mortality in the elderly.

7 ly for the management of malnutrition in the elderly.

8 to maintain central T-cell tolerance in the elderly.

9 eof explain gait and balance function in the elderly.

10 ildren, immunocompromised adults, and in the elderly.

11 -specific incidence rates of BCC in the very elderly.

12 as cardiovascular health has improved in the elderly.

13 inopathic neurodegenerative dementias of the elderly.

14 to the elevations in serum cytokines in the elderly.

15 e to the loss of speech understanding in the elderly.

16 ations for the function of the atrial in the elderly.

17 nary perfusion and diastolic function in the elderly.

18 ealing wounds are a common problem among the elderly.

19 s on motor skill memory consolidation in the elderly.

20 elated pathologies and health burdens in the elderly.

21 ential to reduce overall disease risk in the elderly.

22 es that cause vision loss, especially in the elderly.

23 ants, immunocompromised individuals, and the elderly.

24 and the most common cause of dementia in the elderly.

25 -related hospitalizations, especially in the elderly.

26 d is the leading cause of vision loss in the elderly.

27 hildren, immunocompromised patients, and the elderly.

28 vity, facilitating accurate migration in the elderly.

29 children, immunocompromised adults, and the elderly.

30 is the most common form of blindness in the elderly.

31 ction for colorectal liver metastases in the elderly.

32 ts, but bowel surgery was more common in the elderly (13% after 5 years vs 10% in adults) (P < .001).

33 h probable CAA) and 138 controls (96 healthy elderly, 42 deep intracerebral haemorrhage controls) and

34 lities in patients aged <65 years versus the elderly (58% versus 71%; P = 0.01).

35 = 0.02]), lower CIP susceptibilities in the elderly (64% versus 81%; P = 0.03), SNF versus home (35%

36 cuits partially underpin the difficulty that elderly adults experience with respect to attending to s

37 Elderly adults may master challenging cognitive demands

38 vels and incident T2D in the middle-aged and elderly adults; instead, direct bilirubin levels were as

39 identification of ATTR V122I amyloidosis in elderly African American patients with HF.

40 METHODS AND Elderly (aged >/=66 years) Medicare beneficiaries enroll

41 with adverse health outcomes, especially in elderly American adults.

42 tra-intestinal manifestations was similar in elderly and adult patients, but bowel surgery was more c

43 ome insight into the differences between the elderly and adults in terms of response to treatment and

44 ed-loop controlled wearable robots to assist elderly and disabled subjects and to improve their quali

45 f morbidity and mortality in the paediatric, elderly and immune-compromised populations(1,2).

46 RSV can also cause severe complications in elderly and immunocompromised individuals.

47 individuals and disappointing results in the elderly and immunocompromised patients.

48 raft failure were generally consistent among elderly and nonelderly subgroups and among pairs receivi

49 o-CII protein and appears to manifest in the elderly and preferentially affect the kidneys.

50 Patients with ABBA disease were elderly and presented with AKI and subnephrotic proteinu

51 ffect and cost-effectiveness of the existing elderly and risk group vaccination programme under the n

52 ially those aged 1-4 years), falls among the elderly, and suicide among young female adults are urgen

53 us (RSV) represents a threat to infants, the elderly, and the immunocompromised.

54 Elderly asthmatics are at a higher risk for morbidity an

55 Evidence suggests that elderly asthmatics are more likely to be underdiagnosed

56 pies expands, it will be critical to include elderly asthmatics in large clinical trials so that ther

57 Eighty-five elderly asthmatics, 74 younger asthma patients, and 114

58 Tau and Abeta deposits in the elderly brain generally display well-defined hierarchica

59 ally organized tau and Abeta deposits in the elderly brain.

60 diagnosis and management of rhinitis in the elderly by comparison with an adult population.

61 stic anemia, and although more common in the elderly, can occur at any age.

62 Elderly cancer patients treated with ionizing radiation

63 d with those with primary cardiac diagnoses, elderly CICU patients with primary noncardiac diagnoses

64 The increasing proportions of elderly citizens, the growing prevalence of chronic dise

65 In this low-risk elderly cohort, 46% of patients with a nonbacterial AURI

66 , cardiac mechanics, and LV remodeling in an elderly community-based population.

67 Although most glaucoma patients are elderly, congenital glaucoma and glaucomas of childhood

68 ally those offering better protection in the elderly), could have an even stronger effect on annual i

69 rly DCD kidneys, 45.5% of those who received elderly DBD kidneys, and approximately 26% of those who

70 eservation is warranted if the allocation of elderly DCD grafts to elderly recipients is to be expand

71 x regression analysis, elderly recipients of elderly DCD kidneys had a 5-year mortality risk higher t

72 erly recipients, 63.8% of those who received elderly DCD kidneys, 45.5% of those who received elderly

73 n vitro neutrophil migratory accuracy in the elderly deteriorated as the severity of the infectious p

74 nts receiving a graft from either a young or elderly donor, stratified by donor type.

75 Unexpectedly, elderly donors (>90 yrs) harbor fewer mutations than pre

76 ts (>/=65 years) receive a donor kidney from elderly donors after brain death (DBD) or after circulat

77 Analysis of samples from 77 young and elderly donors revealed a novel and robust aging signatu

78 tance criteria, particularly of kidneys from elderly donors.

79 Elderly (Eld) (>/=60 years) recipients are receiving ren

80 evant end points for transplant-eligible and elderly fit patients with MM.

81 two independent population-based cohorts of elderly from the Netherlands and Germany (n = 13,044).

82 f successful liver transplantation (LT) with elderly grafts (EG), advanced donor age is considered a

83 e of predefined serious complications in the elderly group (5 events vs. 1 event; P = 0.01).

84 ymptom rate at last follow-up was 64% in the elderly group versus 86% in the younger cohort (P = 0.02

85 ished the probable AD group from the healthy elderly group with a better Area Under the Receiving Ope

86 in EMG --> SBP causality was observed in the elderly group, compared to the young group.

87 k of serious complications was higher in the elderly group.

88 emained constant for younger (<45 years) and elderly (>/=65 years) patients.

89 The number of very elderly (>/=80 years) is rapidly growing worldwide.

90 Participants were elderly (>68 years) patients undergoing major elective n

91 (pediatric, <18 years; adults, 18-59 years; elderly, >/=60 years).

92 ts with urothelial cancer, most of whom were elderly, had poor prognostic factors, or had serious com

93 The elderly have reduced humoral immunity, as manifested by

94 ry performance (P=0.0003) in 3,346 young and elderly healthy adults.

95 Even in the elderly, higher CVH status is highly beneficial regardin

96 ults suggest that older mice, in contrast to elderly humans, live under a high sleep pressure.

97 oencephalogram (EEG) slow waves in young and elderly humans.

98 in Hong Kong particularly among children and elderly in 1998-2013.

99 ion in influenza-related mortality among the elderly in a Japanese school-based program.

100 ospitalized IBD patients were that they were elderly in CD and were on higher doses of steroids.

101 heat-related hospitalizations (HH) among the elderly in presence of strong seasonality and by assessi

102 oth in dCA and sCA, in this healthy group of elderly, in a range from low to high CA efficiency.

103 ole population (by 13.5%), but not among the elderly (increased by 2%) due to a substantial increase

104 tudy conducted a prospective analysis of 942 elderly individuals (70->/=90 years) with magnetic reson

105 genes are frequently found to be mutated in elderly individuals along with clonal expansion of hemat

106 rs in a cohort including cognitively healthy elderly individuals and individuals at early symptomatic

107 chain transcript sequences in both young and elderly individuals before and after influenza vaccinati

108 for a different management approach for many elderly individuals considered to have CKD by current cr

109 tic biomarkers from the verbal utterances of elderly individuals could help the clinical diagnosis of

110 coronary heart disease, and stroke events in elderly individuals from the community.

111 cal and cognitive functioning as more frail, elderly individuals survive with health problems, that i

112 Cognitively normal elderly individuals who engage in specific mentally stim

113 entified in blood cells from normal, healthy elderly individuals with clonal hematopoiesis who are at

114 higher than has previously been reported in elderly individuals without cancer (about 10%).

115 association between Abeta and gait speed in elderly individuals without dementia and to study the in

116 This cross-sectional analysis included 183 elderly individuals without dementia, including a cognit

117 tion is associated with slower gait speed in elderly individuals without dementia; however, this asso

118 In 50% of the elderly individuals, a large space in the repertoire was

119 fic CD4(+) T cell responses, even those from elderly individuals, are highly functional and are direc

120 Examples to prevent falls, especially among elderly individuals, include exercise programs, home mod

121 iverticula, a condition usually diagnosed in elderly individuals.

122 ic syndrome (MDS), develop preferentially in elderly individuals.

123 d a lower risk of CVD and total mortality in elderly individuals.

124 d to fainting and falls often experienced by elderly individuals.

125 cination would reduce the number of low-risk elderly influenza cases to a greater extent than would v

126 nt Questionnaire on Cognitive Decline in the Elderly (IQCODE); neuropsychiatric symptoms were evaluat

127 Major depressive disorder (MDD) in the elderly is a risk factor for dementia, but the precise b

128 the mobilization of free fatty acids in the elderly is accompanied by increased visceral adiposity,

129 The incidence of BCC among the very elderly is high and increasing.

130 Lower survival after stroke among the elderly is inevitable, but there may be opportunities fo

131 and assimilation of meat amino acids in the elderly is lower when meat is poorly cooked.

132 demonstrated, for the first time, in normal elderly its link to AD-like hypometabolism and to AD-lik

133 Elderly long-term care residents often exhibit a myriad

134 -based algorithm: nonelderly disabled, frail elderly, major complex chronic, minor complex chronic, s

135 CASE REPORT: We report a case of an elderly male with incidental finding of mediastinal lesi

136 ic dysfunctions between 1993 and 2011 in 587 elderly (mean = 70 (standard deviation, 7) years of age)

137 Spouses of patients with HF were elderly (mean age, 71 years), often had comorbid conditi

138 Among elderly Medicare enrollees, the risk for interval CRC wa

139 iated with a reduced risk of cataracts in an elderly Mediterranean population even after adjusting by

140 ake and the risk of incident cataracts in an elderly Mediterranean population.

141 tosterone with carotid plaque composition in elderly men and postmenopausal women with carotid athero

142 l effects on lean body mass and leg power in elderly men.

143 keletal muscle mass and physical function in elderly men.In this parallel-group randomized trial, 29

144 fluence myocardial structure and function in elderly mice.

145 -15 receptor binding subunit, IL-15ralpha in elderly myotubes confirmed that autocrine concentrations

146 We examined 187 elderly nursing home residents (aged 80-102 years) and 5

147 ion (AMD) is a frequent, complex disorder in elderly of European ancestry.

148 rodeoxyglucose (FDG) in 90 clinically normal elderly of the Harvard Aging Brain Study.

149 offspring (8 M, 8 F, 5.6 years), and normal elderly (OLD) baboons (6 M, 6 F, mean 15.9 years) reveal

150 uivalent approximately 25 years), and normal elderly (OLD) baboons (6 male, 6 female, mean 15.9 years

151 that exponentially growing fibroblasts from elderly (old) male donor subjects (70, 72, and 78 years)

152 One death occurred in the study in an elderly participant in the monotherapy group who died of

153 Elderly participants had significantly higher levels of

154 Among 5801 elderly participants in the ARIC study (Atherosclerosis

155 ss was inversely related to the CRP level in elderly participants, but not seniors, and those with co

156 form of the disease, often in vulnerable or elderly patient populations.

157 An increasing number of elderly patients (>/=65 years) receive a donor kidney fr

158 rospinal fluid (CSF) from cognitively intact elderly patients (N = 28) with MDD and age- and gender-m

159 ; and 50-69 y, 26.3%), and then increased in elderly patients 70 years and older (31.9%).

160 Using 2003 to 2013 Medicare data, we grouped elderly patients admitted to CICUs into 2 categories bas

161 Although the proportion of elderly patients among renal transplant recipients has i

162 LST to a nationally representative cohort of elderly patients Analysis of Surveillance, Epidemiology,

163 line in upfront chemoimmunotherapy for these elderly patients and highlight the need of prospective c

164 oregionally confined head and neck cancer in elderly patients and propose a practical treatment algor

165 ces in pharmacologic treatment of adults and elderly patients are not necessarily because of a milder

166 While elderly patients are underrepresented in clinical trials

167 Although most elderly patients experience symptom resolution after dac

168 w-up period of 4.2 years (range, 0-9 years), elderly patients had less IBD-specific outpatient health

169 The high mortality rate in critically ill elderly patients has led to questioning of the beneficia

170 stoperative delirium occurs in 10% to 60% of elderly patients having major surgery and is associated

171 Among critically ill elderly patients in France, a program to promote systema

172 reatment regimens are often not suitable for elderly patients or for patients in developing countries

173 esulted in improved survival and has allowed elderly patients or those with comorbidity to receive an

174 r systematic ICU admission in critically ill elderly patients reduces 6-month mortality compared with

175 Head and neck cancer in elderly patients represents a major health burden becaus

176 gth of stay and in operative mortality among elderly patients suggest areas where regionalization may

177 s needed to understand the decision to admit elderly patients to the ICU.

178 In a cohort of 453 475 elderly patients undergoing PCI, 39 850 developed AKI (8

179 patients with pediatric or adult-onset IBD, elderly patients used fewer biologics and immunomodulato

180 ages, the number of operations performed on elderly patients will likely increase.

181 More than half of all elderly patients with a CICU stay across the United Stat

182 Methods We used SEER-Medicare data for elderly patients with a new diagnosis of advanced-stage

183 Purpose Elderly patients with acute myeloid leukemia (AML) have

184 enib is associated with improved survival in elderly patients with advanced HCC; however, it is not c

185 androlone significantly improves survival in elderly patients with AML without increasing toxicity.

186 g proteomics, we identified seven additional elderly patients with Apo-CII-rich amyloid deposits, all

187 Additionally, elderly patients with asthma have highest rates of morbi

188 resence of CMV DNA in the blood of adult and elderly patients with bronchial asthma to establish pote

189 black vs white disparities in survival among elderly patients with colorectal cancer (CRC) were becau

190 ne induction chemoimmunotherapy in untreated elderly patients with diffuse large B-cell lymphoma.

191 omide as maintenance therapy with placebo in elderly patients with DLBCL who achieved a complete resp

192 PR to R-CHOP significantly prolonged PFS in elderly patients with DLBCL.

193 Hypofractionated radiotherapy for elderly patients with fair to good performance status is

194 acious without impairing quality of life for elderly patients with good performance status.

195 For elderly patients with HL, BV plus DTIC may be a frontlin

196 Elderly patients with minimal comorbid conditions meetin

197 e MM and the GEM2010MAS65 clinical trial for elderly patients with MM who had minimal residual diseas

198 y available because of the growing number of elderly patients with significant comorbidities or high

199 ar disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems.

200 ased therapies are currently being tested on elderly patients, there are limited data on the function

201 eg-patients with poor performance status and elderly patients-are not specifically addressed, because

202 paroscopic approach on this diverse group of elderly patients.

203 ntation of bone marrow-derived stem cells in elderly patients.

204 tive outcome for allografts, particularly in elderly patients.

205 daily cardiovascular practice as we care for elderly patients.

206 at these benefits continue to be observed in elderly patients.

207 mentia (cases group) and cognitively healthy elderly people (control group); data were collected on t

208 ccounts for memory impairments often seen in elderly people and how Abeta affects this relationship.

209 s the second most common form of dementia in elderly people but has been overshadowed in the research

210 A case-control study was performed in elderly people diagnosed with cognitive impairment with

211 he United Kingdom and Ireland and a trial in elderly people in Norfolk, United Kingdom, were used to

212 ss and strength in the growing population of elderly people is a major health concern for modern soci

213 effects on cognitive decline over 3 years in elderly people with memory complaints.

214 Among elderly people, we found a statistically significant ass

215 argeted treatment is especially relevant for elderly people-who now represent an increasing proportio

216 a substantial loss of healthy life-years in elderly people.

217 ory bowel diseases (IBD) is increasing among elderly persons (60 years or older).

218 of the Medicare population, high-cost frail elderly persons accounted for 43.9% of total potentially

219 Frail elderly persons accounted for most spending related to a

220 y associated with excess hospitalizations in elderly persons aged >/=80 years, with an excess hospita

221 Experimental tests conducted on eight elderly persons and two transfemoral amputees revealed t

222 Elderly persons have the highest influenza-associated ho

223 It can help in monitoring the wellness of elderly persons living alone by unobtrusively monitoring

224 , with the majority concentrated among frail elderly persons.

225 ologies for life-logging and for the care of elderly persons.

226 e-age adults (including pregnant women); and elderly persons.

227 red breathing (SDB) and cognitive decline in elderly persons.

228 and accelerate hematopoietic recovery in the elderly population following myelosuppressive regimens.

229 ng cause of irreversible blindness among the elderly population globally.

230 ies, the generalizability of the NLST in the elderly population has been questioned.

231 e-based normative values when considering an elderly population improves the risk discrimination of d

232 owest fertility and mortality rates, and the elderly population is projected to grow substantially ov

233 is a common retinal vascular disorder in the elderly population of Nepal.

234 actors of retinal vein occlusion (RVO) in an elderly population of Nepal.

235 The growing elderly population worldwide highlights the need to unde

236 been reported previously specifically for an elderly population, in which there may be increased risk

237 In the growing elderly population, the high prevalence of comorbidities

238 ffect speech understanding negatively in the elderly population.

239 ication rates of dacryocystorhinostomy in an elderly population.

240 cardial diseases, which primarily affect the elderly population.

241 ity is, at least, partially preserved in the elderly population.

242 at leads to severe cognitive deficits in the elderly population.

243 nd incident severe AS in a large, unselected elderly population.

244 d potentially protect both the pediatric and elderly populations and support continued development of

245 atory Syncytial Virus (RSV) in pediatric and elderly populations is well recognized.

246 Even though elderly populations lack visible or other clinical signs

247 LTCFs generally care for elderly populations who are vulnerable to infection, hav

248 In elderly populations, frailty is associated with higher m

249 yceride levels with longevity and frailty in elderly populations.

250 in older adults, the focus was on studies in elderly populations; studies based solely in the intensi

251 ncement on Medical Status Ratings Twenty-one elderly psychiatric patients had lower levels of psychop

252 survival rate, has become widely adopted in elderly recipients in an old-to-old allocation system.

253 d if the allocation of elderly DCD grafts to elderly recipients is to be expanded.

254 In Cox regression analysis, elderly recipients of elderly DCD kidneys had a 5-year m

255 a 5-year mortality risk higher than that of elderly recipients of young DBD kidneys (hazard ratio, 1

256 2002-2012, and categorized them as young or elderly recipients receiving a graft from either a young

257 Among elderly recipients, 63.8% of those who received elderly

258 a single KT would be enough, particularly in elderly recipients.

259 the relation to type 2 diabetes (T2D) in the elderly remains unclear.

260 We studied 12-hour everolimus (EVL) PK in 16 elderly renal transplant recipients (all whites; 10 men;

261 Our data indicate that elderly renal transplant recipients starting EVL 1 month

262 eshold of pound15 000 per QALY, the low-risk elderly seasonal vaccination programme will cease to be

263 Study of Caregiving), were used to identify elderly stroke survivors and their caregivers.

264 association study in 3,401 nicotine-exposed elderly subjects considering 358 phenotypic traits.

265 In view to preventing sarcopenia, elderly subjects should be advised to favor the consumpt

266 Free thyroxine levels in middle-aged and elderly subjects were positively associated with atheros

267 oup of healthy young subjects and a group of elderly subjects with Parkinson's disease using an event

268 ions compared with conservative mutations in elderly subjects' vaccine responses, which suggests that

269 0 MBq) scans were obtained in 35 age-matched elderly subjects, including 10 probable AD, 15 amnestic

270 oire exhibited premature stop codons in some elderly subjects, indicating that aging may negatively a

271 es were 19% thinner in cultures derived from elderly subjects, rIL-15 increased the thickness of myot

272 olated from the skeletal muscle of young and elderly subjects.

273 force for SVD on gait impairment in healthy elderly subjects.

274 ate postprandial meat protein utilization in elderly subjects.The study recruited 10 elderly voluntee

275 The elderly tend to have a delayed onset of many immune resp

276 This well-tolerated phenotype persisted in elderly TG with no indications of cardiac pathology or p

277 of association with GI bleeding in the very elderly than dabigatran (HR, 0.45; 95% CI, 0.29-0.71) or

278 lute risk of bowel surgery was higher in the elderly than in the general population, but in relative

279 In the elderly, the increase in NVTs, excluding 6C, was more pr

280 s associated with the presence of T2D in the elderly, the pathogenesis and phenotype of late-onset T2

281 drug level in particular patient groups (eg, elderly, the renally impaired, and those with high bleed

282 xtent than would vaccination of the low-risk elderly themselves if the elderly uptake is achieved mor

283 nicopathological features of BCC in the very elderly to guide clinicians and policy makers.

284 tory cytokines, potentially predisposing the elderly to the subsequent development or exacerbation of

285 The cohort consisted of elderly to very old patients (mean age 79.2 +/- 11.5).

286 d focus more specifically on BCC in the very elderly, together with prognostication and their relatio

287 We find that CH is very common in the elderly, trending toward inevitability.

288 on of the low-risk elderly themselves if the elderly uptake is achieved more slowly.

289 al uncertainty exists as to whether low-risk elderly vaccination remains cost-effective, driven by th

290 n in elderly subjects.The study recruited 10 elderly volunteers aged 70-82 y.

291 In this large cohort of US elderly, we provide important new evidence that long-ter

292 accompanies an increase in adiposity in the elderly.We examined the association of sarcopenic obesit

293 ncreasing incidence rates of BCC in the very elderly were found ranging from 13 to 12112 per 100000 p

294 Basal cell carcinoma in the very elderly were more common in men, mostly of the nodular s

295 : (i) to assess the percentage of adults and elderly who are able to use the Allergy Diary, (ii) to s

296 and asthma multimorbidity in adults and the elderly will be compared using validated information and

297 l ageing, n = 13), and neurologically normal elderly with cortical amyloid-beta accumulation (patholo

298 isease cases (n = 19), neurologically normal elderly without amyloid-beta accumulation (normal ageing

299 cancer with preexisting mental illness, and elderly women are of special interest because they exper

300 F) Study (n = 2,103), a prospective study of elderly women in Denmark, we found that impaired fasting