ライフサイエンスコーパス: elderly patient

1 bstitute for transplant, particularly in the elderly patient.

2 at repair, use of EVAR, and the treatment of elderly patients.

3 01) and a lower Nurick score (p<0.0001) than elderly patients.

4 ys and 10.4% (4.4% venous, 5.9% arterial) in elderly patients.

5 timing of aortic valve replacement, even in elderly patients.

6 ated in transplant-eligible patients than in elderly patients.

7 s those with mild initial stroke severity or elderly patients.

8 ity wounds can be challenging, especially in elderly patients.

9 ntraocular manifestations, and management of elderly patients.

10 ortunistic pathogen in immunocompromised and elderly patients.

11 asible and can also be proposed for selected elderly patients.

12 r benefit from recent oncology advances than elderly patients.

13 traumatic wounds that were slow to heal in 3 elderly patients.

14 503 (33.2%) were adults, and 848 (5.1%) were elderly patients.

15 ed data describe practice and outcomes among elderly patients.

16 alignancies, multiple myeloma mainly affects elderly patients.

17 paroscopic approach on this diverse group of elderly patients.

18 each DOAC was similar or superior to VKA in elderly patients.

19 or those aged 80-84 years) than were younger elderly patients.

20 vents, and long-term outcome after CRT among elderly patients.

21 ently associated with all-cause mortality of elderly patients.

22 ntation of bone marrow-derived stem cells in elderly patients.

23 d feasibility of chemoimmunotherapy, even in elderly patients.

24 hat are unique to the growing demographic of elderly patients.

25 survival rates are acceptable, even in very elderly patients.

26 e role of alkylators in myeloma treatment of elderly patients.

27 ), but its clinical usefulness is limited in elderly patients.

28 schemic heart disease, compared with younger elderly patients.

29 r cardiac resynchronization therapy (CRT) in elderly patients.

30 lity rate was significantly higher among the elderly patients.

31 ently associated with all-cause mortality in elderly patients.

32 n are common postanesthesia complications in elderly patients.

33 -dose prasugrel compared with clopidogrel in elderly patients.

34 tive outcome for allografts, particularly in elderly patients.

35 daily cardiovascular practice as we care for elderly patients.

36 at these benefits continue to be observed in elderly patients.

37 nce decreased with age but then increased in elderly patients.

38 outcomes than CAS outcomes noted in the more elderly patients.

39 with a disproportionately high incidence in elderly patients.

40 fficacy of ECT to treat severe depression in elderly patients.

41 the neurological examination particularly of elderly patients.

42 and large numbers of years of life saved in elderly patients.

43 t safety and efficacy of TAVR in select very elderly patients.

44 lowing questions: Should RT be advocated for elderly patients?

45 the 6-year period and remained unchanged for elderly patients (0.8 cases per 1000 discharges in 2007

46 iction model to estimate the outcome of very elderly patients 12 months after being admitted to the I

47 This increase was more prominent in elderly patients (12%) but less so in inpatients (2.6%).

48 e cause-specific survival remained worse for elderly patients (3-year CSS, 60.8%; 95% CI, 59.6%-61.9%

49 ilator-associated pneumonia was higher among elderly patients: 35% in middle-aged patients versus 51%

50 patients with an AIS score of 5, most of the elderly patients (56.33%) had a mild neurologic deficit

51 ; and 50-69 y, 26.3%), and then increased in elderly patients 70 years and older (31.9%).

52 17.6 [6.6]), organ support was higher in the elderly patients (77.0% vs 68.1%, p<0.0001), and median

53 ee-for-service claims data was performed for elderly patients admitted for hemorrhagic stroke in 2008

54 hanges in primary noncardiac diagnoses among elderly patients admitted to a CICU during the past deca

55 Using 2003 to 2013 Medicare data, we grouped elderly patients admitted to CICUs into 2 categories bas

56 safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.

57 Elderly patients (age >/= 70 years) with limited-stage s

58 n the entire cohort and 6-month mortality in elderly patients aged 65 years or older matched to data

59 rge nationally representative cohort of 3418 elderly patients (aged >/= 70 years) with CKD undergoing

60 temozolomide alone or radiotherapy alone in elderly patients (aged >/=60 years) with GBM; articles w

61 The appropriate treatment approach for elderly patients (aged >65 years) with GBM remains uncle

62 Although the proportion of elderly patients among renal transplant recipients has i

63 LST to a nationally representative cohort of elderly patients Analysis of Surveillance, Epidemiology,

64 staphyloma might cause visual impairment in elderly patients and can be considered atypical forms of

65 l lymphoma, leg type (PCDLBCL-LT), occurs in elderly patients and has been considered as a lymphoma w

66 line in upfront chemoimmunotherapy for these elderly patients and highlight the need of prospective c

67 ng several lifestyle factors in non-demented elderly patients and moderately positive interim results

68 Extreme mortality after ECMO in elderly patients and patients requiring cardiopulmonary

69 oregionally confined head and neck cancer in elderly patients and propose a practical treatment algor

70 declining renal function was more common in elderly patients and those with cardiovascular comorbidi

71 Elderly patients and those with hyperlipidemia experienc

72 nts can induce hepatotoxicity, especially in elderly patients and those with polypharmacy.

73 Cerebral amyloid angiopathy is common among elderly patients, and is associated with an increased ri

74 Male patients, elderly patients, and patients with dementia were at sig

75 Elderly patients are especially likely to experience feb

76 aortic valve replacement (TAVR) in the very elderly patients are limited, as they often represent on

77 Elderly patients are more likely to have NASH and advanc

78 accurate methods for risk stratification of elderly patients are necessary to decrease the occurrenc

79 ces in pharmacologic treatment of adults and elderly patients are not necessarily because of a milder

80 Colon resections in elderly patients are often done in emergent settings.

81 orting of safety and efficacy information in elderly patients are summarized.

82 Elderly patients are the fastest-growing group in need o

83 While elderly patients are underrepresented in clinical trials

84 eg-patients with poor performance status and elderly patients-are not specifically addressed, because

85 motherapy regimens, but optimal treatment of elderly patients as well for as patients with limited or

86 Mortality rates were higher in elderly patients at ICU discharge (elderly, 26.5%; older

87 s recommended to assess the vulnerability of elderly patients, but its integration in cancer treatmen

88 ciated with increased incidence of stroke in elderly patients compared with their young counterparts

89 pected to improve preoperative decisions for elderly patients considered for colorectal surgery.

90 al consideration as all other burn patients, elderly patients continue to have substantially poorer o

91 d analysis of 869 individual newly diagnosed elderly patient data from 3 prospective trials.

92 Coupled with this immune dysfunction, elderly patients demonstrate impaired wound healing with

93 rologic outcome in successfully resuscitated elderly patients depends on cardiac arrest characteristi

94 reater risk of postoperative mortality among elderly patients despite less aggressive treatment.

95 benefit from the addition of oxaliplatin in elderly patients (DFS hazard ratio [HR], 0.94; 95% CI, 0

96 y surgical diagnoses were more prevalent for elderly patients (elderly, 39.8%; older, 25.1%; younger,

97 new-user cohorts of propensity score-matched elderly patients enrolled in Medicare who initiated dabi

98 though under-represented in clinical trials, elderly patients experience similar survival outcomes co

99 Although most elderly patients experience symptom resolution after dac

100 30-day readmission rates that are similar to elderly patients for HF, AMI, and pneumonia.

101 Antipsychotic drugs are widely prescribed to elderly patients for the treatment of a variety of psych

102 rations, may have more pronounced effects in elderly patients, given their predisposition to altered

103 a multicenter, open-label, phase III trial, elderly patients >/= 70 years old with a PS of 0 to 2 an

104 ren (</=18 years), adults (19-54 years), and elderly patients (>/=55 years).

105 icantly lower mortality rate was observed in elderly patients (>/=60 y old) with stage I disease.

106 An increasing number of elderly patients (>/=65 years) receive a donor kidney fr

107 the National Cancer Database was queried for elderly patients (>/=65 years) with newly diagnosed GBM

108 Elderly patients had a greater number of decompressed le

109 Elderly patients had a higher cardiac arrest rate (2.2 v

110 Compared to nonelderly patients with NAFLD, elderly patients had a higher prevalence of NASH (56% ve

111 Elderly patients had a worse preoperative health status

112 Elderly patients had higher stroke and major bleeding ra

113 w-up period of 4.2 years (range, 0-9 years), elderly patients had less IBD-specific outpatient health

114 Within 4 hours of cardiac arrest, elderly patients had significantly lower mean heart rate

115 Elderly patients had similar improvements in clinical sy

116 cytic leukaemia; however, its application in elderly patients has been restricted by substantial myel

117 The high mortality rate in critically ill elderly patients has led to questioning of the beneficia

118 eplacement, its adoption in the treatment of elderly patients has not been uniform, partly because of

119 Elderly patients have a decreased tolerance to anemia an

120 stoperative delirium occurs in 10% to 60% of elderly patients having major surgery and is associated

121 As the population ages, the number of elderly patients having surgery is likewise increasing a

122 h pneumonia-specific ICU admission rates for elderly patients identify a group of hospitals that may

123 However, elderly patients (ie >/=65 years of age) are still more

124 e effective communication with seriously ill elderly patients if they had a structured, standardized

125 rated as a result of under-representation of elderly patients in clinical trials and avoidance of the

126 Among critically ill elderly patients in France, a program to promote systema

127 Polypharmacy is a well known problem in elderly patients in general, but its prevalence and effe

128 : The incidence of OPSCC is increasing among elderly patients in the United States, likely driven by

129 he increase was significantly less marked in elderly patients in whom undertreatment is a concern.

130 x antithrombotic therapy (CAT) prescribed to elderly patients increases the risk of gastrointestinal

131 intensity suggest selection of less comorbid elderly patients, indicating possible rationing based on

132 Colorectal surgery in elderly patients is associated with significantly higher

133 Risk prediction in elderly patients is increasingly relevant due to longer

134 The incidence of colorectal cancer in elderly patients is likely to increase, but there is a l

135 ure, the leading cause of hospitalization of elderly patients, is correlated with myocardial fibrosis

136 sociated head and neck cancers decreased for elderly patients (larynx: APC, -1.54; 95% CI, -2.00 to -

137 Uniform vascular access guidelines for elderly patients may be inappropriate because of the com

138 ore were higher for nonelderly patients than elderly patients (Modified Early Warning Score area unde

139 n/exclusion criteria suggests that BIPA made elderly patients more likely (relative likelihood, 1.36;

140 rospinal fluid (CSF) from cognitively intact elderly patients (N = 28) with MDD and age- and gender-m

141 rnative to radical cystectomy, especially in elderly patients not well suited for surgery.

142 Therefore, in many elderly patients, observation is the best therapeutic op

143 For chronically critically ill elderly patients on mechanical ventilation, prognosis fo

144 What should be the criteria to accept elderly patients on the waiting list for RT?

145 reatment regimens are often not suitable for elderly patients or for patients in developing countries

146 esulted in improved survival and has allowed elderly patients or those with comorbidity to receive an

147 difference between adolescents, adults, and elderly patients (OS rate of 90%, 84%, and 62%, respecti

148 s, but fewer preexisting comorbidities among elderly patients (p = 0.007), who received a shorter dur

149 Bottom Line: For fit elderly patients platinum-based combination is associate

150 y capable of protecting immunocompromised or elderly patient populations not reliably protected by ex

151 form of the disease, often in vulnerable or elderly patient populations.

152 Three elderly patients presented with unilateral keratitis.

153 Restricted to mechanically ventilated elderly patients, rates ranged from 13.9 to 30.1/10,000

154 r systematic ICU admission in critically ill elderly patients reduces 6-month mortality compared with

155 tality rate comparable to that of waitlisted elderly patients remaining on dialysis.

156 Head and neck cancer in elderly patients represents a major health burden becaus

157 In elderly patients (RICOVER-60 study), HRPFS-male was 1.1

158 For selected elderly patients, RT was shown to be superior to dialysi

159 eatment decisions for potentially vulnerable elderly patients should take into account data obtained

160 However, after 4 years of follow-up, elderly patients showed worse survival and the cause of

161 There have not been elderly patient-specific trials of these therapies.

162 utcome and long-term survival are unknown in elderly patients successfully resuscitated after out-of-

163 gth of stay and in operative mortality among elderly patients suggest areas where regionalization may

164 On subanalysis of adults and elderly patients, the prevalence of domestic violence in

165 ar disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems.

166 ased therapies are currently being tested on elderly patients, there are limited data on the function

167 However, the corresponding HRs (95% CIs) for elderly patients (those 75-85 years old) were only 0.88

168 trajectories in burned adults versus burned elderly patients to gain novel insights and better under

169 s needed to understand the decision to admit elderly patients to the ICU.

170 pt their practice habits when taking care of elderly patients to try to mitigate the effects of the a

171 onges did not reduce the incidence of SSI in elderly patients treated with a hemiarthroplasty because

172 l of this study was to address this issue in elderly patients treated with conventional-dose chemothe

173 2 studies that reported overall survival in elderly patients treated with radiotherapy alone.

174 el 2 study that reported overall survival in elderly patients treated with temozolomide alone, and 4

175 ortance for optimizing surgical outcomes for elderly patients undergoing ambulatory surgery.

176 ence-based anesthetic and analgesic care for elderly patients undergoing elective operations on an am

177 anded use of ambulatory surgery for managing elderly patients undergoing elective surgery procedures.

178 Perioperative mortality rates in elderly patients undergoing emergent general/vascular op

179 f care is associated with worse outcomes for elderly patients undergoing major surgery.

180 djusted 30-day episode Medicare payments for elderly patients undergoing one of six procedures for re

181 In a cohort of 453 475 elderly patients undergoing PCI, 39 850 developed AKI (8

182 patients with pediatric or adult-onset IBD, elderly patients used fewer biologics and immunomodulato

183 The number of elderly patients using anticoagulant and antiplatelet tr

184 d that active hypertension treatment in very elderly patients was beneficial by reducing blood pressu

185 Ventilator-associated pneumonia in elderly patients was more frequently caused by Enterobac

186 ed States to determine if aggressive care of elderly patients was warranted.

187 iated pneumonia, whereas more episodes among elderly patients were caused by Enterobacteriaceae.

188 fficacy and device-related adverse events in elderly patients were comparable with that of nonelderly

189 Elderly patients were defined as those 65 years or older

190 Eleven elderly patients were evaluated as controls (mean age, 7

191 Forty-seven depressed elderly patients were included in this analysis.

192 Staphylococcal isolates from elderly patients were more likely to be MR, as were S au

193 Elderly patients were more likely to have do-not-resusci

194 arrest in nonelderly patients compared with elderly patients, which has important implications for h

195 g about the utility of life support for very elderly patients who are admitted to the ICU.

196 that CRT should be the preferred strategy in elderly patients who are expected to tolerate the toxici

197 has been reported that approximately 30% of elderly patients who survive stroke develop delayed deme

198 responses in cases of ASB compared to UTI in elderly patients who were hospitalized upon injury.

199 Survival is further limited in elderly patients, who are often unable to tolerate multi

200 Nonvalvular atrial fibrillation is common in elderly patients, who face an elevated risk of stroke bu

201 ce-based perioperative care programs for the elderly patients will assume increased importance.

202 ounger patients, a substantial proportion of elderly patients will have long-term survival.

203 ages, the number of operations performed on elderly patients will likely increase.

204 the key to improving quality of life for the elderly patient with cancer is an awareness of their spe

205 More than half of all elderly patients with a CICU stay across the United Stat

206 Methods We used SEER-Medicare data for elderly patients with a new diagnosis of advanced-stage

207 for younger, lower-body-weight patients and elderly patients with acute coronary syndromes to mitiga

208 Recent findings indicate that elderly patients with acute kidney injury (AKI) have an

209 Purpose Elderly patients with acute myeloid leukemia (AML) have

210 The prognosis of elderly patients with acute myeloid leukemia (AML) is st

211 g surgical decision making for seriously ill elderly patients with acute surgical conditions.

212 However, the outcomes in elderly patients with advanced CKD who receive permanent

213 In conclusion, most elderly patients with advanced CKD who received predialy

214 Even in elderly patients with advanced cSCC, cetuximab was effic

215 t-effectiveness associated with sorafenib in elderly patients with advanced HCC.

216 enib is associated with improved survival in elderly patients with advanced HCC; however, it is not c

217 Here, in elderly patients with advanced non-small-cell lung cance

218 In elderly patients with advanced NSCLC, treatment allocati

219 care, which may improve quality of life for elderly patients with advanced renal failure, will conti

220 ase as a risk factor and improves outcome of elderly patients with aggressive B-cell lymphoma.

221 iweekly CHOP-14 With or Without Rituximab in Elderly Patients With Aggressive CD20+ B-Cell Lymphomas)

222 s were confirmed in the validation cohort of elderly patients with AML (HR 11.08 [3.23-38.06]).

223 trial of decitabine followed by selinexor in elderly patients with AML has been initiated.

224 androlone significantly improves survival in elderly patients with AML without increasing toxicity.

225 ddition of the kinase inhibitor sorafenib in elderly patients with AML.

226 ies such as BI 836858 with azanucleosides in elderly patients with AML.

227 schemic stroke, and cognitive dysfunction in elderly patients with and without Alzheimer's Disease (A

228 g proteomics, we identified seven additional elderly patients with Apo-CII-rich amyloid deposits, all

229 ways mediating inflammation and pain in most elderly patients with ASB are not quantitatively differe

230 Additionally, elderly patients with asthma have highest rates of morbi

231 donors can provide durable remission even in elderly patients with BPDCN.

232 use and breast cancer-specific mortality for elderly patients with breast cancer with and without men

233 resence of CMV DNA in the blood of adult and elderly patients with bronchial asthma to establish pote

234 Elderly patients with BVI, caused by persistent amblyopi

235 oaches, GCE models improve stratification of elderly patients with cancer according to their risk of

236 l assessment, and oncologic prognostication, elderly patients with cancer can do as well in terms of

237 be of great importance as the population of elderly patients with cancer increases in the coming yea

238 as life expectancy increases, the number of elderly patients with cancer is increasing.

239 lanned hospitalizations in the population of elderly patients with cancer is unknown.

240 ay of permanent access placement in selected elderly patients with CKD.

241 black vs white disparities in survival among elderly patients with colorectal cancer (CRC) were becau

242 tensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure randomize

243 f AVR with a cumulative incidence of >40% in elderly patients with degenerative AS who underwent eith

244 ute effect of antipsychotics on mortality in elderly patients with dementia may be higher than previo

245 ne induction chemoimmunotherapy in untreated elderly patients with diffuse large B-cell lymphoma.

246 rituximab schedule are the best reported for elderly patients with DLBCL to date.

247 VDD is a risk factor for elderly patients with DLBCL treated with R-CHOP.

248 omide as maintenance therapy with placebo in elderly patients with DLBCL who achieved a complete resp

249 PR to R-CHOP significantly prolonged PFS in elderly patients with DLBCL.

250 h better outcomes than sublobar resection in elderly patients with early-stage NSCLC.

251 Hypofractionated radiotherapy for elderly patients with fair to good performance status is

252 or biopsy, accepted treatment paradigms for elderly patients with GBM include combined-modality ther

253 ported survival data related to treatment of elderly patients with GBM using either temozolomide alon

254 n this analysis of multimodality therapy for elderly patients with GBM, OS was superior with CMT comp

255 emozolomide alone with radiotherapy alone in elderly patients with GBM.

256 temozolomide monotherapy in the treatment of elderly patients with GBM.

257 Unplanned hospitalizations among elderly patients with GI cancer are common.

258 rs for early unplanned hospitalization among elderly patients with GI cancer.

259 The optimal management for elderly patients with glioblastoma (GBM) is controversia

260 acious without impairing quality of life for elderly patients with good performance status.

261 For elderly patients with HL, BV plus DTIC may be a frontlin

262 tigating improved therapeutic strategies for elderly patients with HPV-positive OPSCC should be perfo

263 Elderly patients with increased risk for postoperative c

264 In elderly patients with limited-stage small-cell lung canc

265 For elderly patients with mantle cell lymphoma (MCL), there

266 ndamustine (R-B) as first-line treatment for elderly patients with MCL.

267 Elderly patients with minimal comorbid conditions meetin

268 In elderly patients with mitral regurgitation, mitral valve

269 e MM and the GEM2010MAS65 clinical trial for elderly patients with MM who had minimal residual diseas

270 Compared to nonelderly patients with NASH, elderly patients with NASH had higher rates of advanced

271 Survival outcome for elderly patients with newly diagnosed diffuse large B-ce

272 ation of CMP was observed to be effective in elderly patients with newly diagnosed MM.

273 ation was associated with worse prognosis in elderly patients with non-small cell lung cancer (NSCLC)

274 estinal hemorrhage compared with warfarin in elderly patients with nonvalvular atrial fibrillation.

275 en the unique challenges related to treating elderly patients with OPSCC, their limited enrollment in

276 over time were observed for both younger and elderly patients with OPSCC.

277 erated and gave long-term survival in 36% of elderly patients with Ph(+) ALL.

278 between a hospital's ICU admission rate for elderly patients with pneumonia and the quality of care

279 with the highest rates of ICU admission for elderly patients with pneumonia; such hospitals were les

280 Elderly patients with previously untreated metastatic co

281 al activity in a previous phase 1-2 study in elderly patients with relapsed or refractory acute myelo

282 with advanced or metastatic thyroid cancer, elderly patients with renal insufficiency or patients wi

283 ool of ECD kidneys and to rapidly transplant elderly patients with satisfactory results because of th

284 le in determining the surgical interventions elderly patients with serious illness receive.

285 e current indications, approximately 290,000 elderly patients with severe AS are TAVR candidates.

286 Elderly patients with severe mitral regurgitation should

287 alve surgery can be safely performed in most elderly patients with severe mitral regurgitation.

288 y available because of the growing number of elderly patients with significant comorbidities or high

289 In elderly patients with type 2 diabetes linagliptin was ef

290 ptin, a dipeptidyl peptidase-4 inhibitor, in elderly patients with type 2 diabetes.

291 transfusion strategy in a high-risk group of elderly patients with underlying cardiovascular disease

292 In conclusion, in elderly patients with unprovoked VTE who have stopped AC

293 Up to 40% of elderly patients with untreated diffuse large B-cell lym

294 omide with R-CHOP21 is effective and safe in elderly patients with untreated DLBCL.

295 combination of lenalidomide and R-CHOP21 in elderly patients with untreated DLBCL.

296 Use of MPT-T or mPR-R in elderly patients with untreated MM demonstrates no stati

297 titatively different from those seen in most elderly patients with UTI and warrant larger clinical st

298 New temperature rise was less common in elderly patients with ventilator-associated pneumonia, w

299 ture and to provide guidance on how to treat elderly patients within three broad stages: (1) metastat

300 nical implementation of CPC-based therapy in elderly patients would benefit tremendously from underst