ライフサイエンスコーパス: electron transport chain

1 ochrome c oxidoreductase (complex III of the electron transport chain).

2 e Krebs cycle and is located upstream of the electron transport chain.

3 y and nanomolar potency as complex II of the electron transport chain.

4 buildup of energy metabolites that feed the electron transport chain.

5 of a reduction signal in the photosynthetic electron transport chain.

6 mobile electron carriers in the respiratory electron transport chain.

7 +)), a neurotoxin that inhibits complex I of electron transport chain.

8 nit of complex I (NADH dehydrogenase) in the electron transport chain.

9 th the reducing equivalents generated by the electron transport chain.

10 with decreased activity of the mitochondrial electron transport chain.

11 respiration at the level of complex I of the electron transport chain.

12 ofactors and catalysts in the photosynthetic electron transport chain.

13 esis with maintaining the redox poise of the electron transport chain.

14 olony variants (SCVs) that lack a functional electron transport chain.

15 udy elements of the organohalide respiratory electron transport chain.

16 dicative of an impaired redox balance of the electron transport chain.

17 dogenous superoxide (O2(*-)) produced in the electron transport chain.

18 in production in the absence of a functional electron transport chain.

19 nophoric uncoupling and/or inhibition of the electron transport chain.

20 a rate-limiting enzyme of the mitochondrial electron transport chain.

21 olating and examining different parts of the electron transport chain.

22 fer of electrons from NADH to enzymes in the electron transport chain.

23 evels of the terminal quinol oxidases of the electron transport chain.

24 molecule that participates in the bacterial electron transport chain.

25 one, which inhibit different elements of the electron transport chain.

26 he conductances of different sections of the electron transport chain.

27 luding red chlorophylls and cofactors of the electron transport chain.

28 tion of reactive oxygen species (ROS) by the electron transport chain.

29 remove excess energy from the photosynthetic electron transport chain.

30 compensate for a drop in the activity of the electron transport chain.

31 he Krebs cycle and reduces ubiquinone in the electron transport chain.

32 ic reducing equivalents to the mitochondrial electron transport chain.

33 is the terminal enzyme of the mitochondrial electron transport chain.

34 potential is generated by the proton-pumping electron transport chain.

35 echanism of action, which is to preserve the electron transport chain.

36 erload response, protein catabolism, and the electron transport chain.

37 e oxygen species due to overreduction of the electron transport chain.

38 sential lipid component of the mitochondrial electron transport chain.

39 ubunit terminal complex of the mitochondrial electron transport chain.

40 rimental overreduction of the photosynthetic electron transport chain.

41 active oxygen species from the mitochondrial electron transport chain.

42 aximal activity of complexes I and II of the electron transport chain.

43 downstream of complex I in the mitochondrial electron transport chain.

44 asal activities of complexes I and II of the electron transport chain.

45 cted to the light-dependent reactions of the electron transport chain.

46 leading to dysfunction of complex II of the electron transport chain.

47 xide generation at complexes I or III of the electron transport chain.

48 rial respiration due to lack of NADH for the electron transport chain.

49 to water without involving cytochrome-linked electron transport chain.

50 by slowing respiration at the mitochondrial electron transport chain.

51 participating in redox reactions within the electron transport chain.

52 t characterized complex of the mitochondrial electron transport chain.

53 rough complex I and II, respectively, of the electron transport chain.

54 bition of Complex I within the mitochondrial electron transport chain.

55 fer of electrons to O2 via the mitochondrial electron transport chain.

56 lectron leak occurring at complex III of the electron transport chain.

57 of cytochrome c oxidase in the mitochondrial electron transport chain.

58 lates with the redox state of photosynthetic electron transport chain.

59 inant, physiologically relevant state of the electron transport chain.

60 rease in expression of genes involved in the electron transport chain.

61 reduced forms residing in the mitochondrial electron-transport chain.

62 ed genes and highlighted re-modelling of the electron transport chains.

63 te dehydrogenase activity (complex II of the electron transport chain); 3) increase catalase activity

64 spongin C, of chloroplasts and mitochondrial electron transport chains, 3-(3,4-dichlorophenyl)-1,1-di

65 Complex I (CI) of the electron transport chain, a large membrane-embedded NADH

66 n is associated with a dramatic reduction in electron transport chain abundance.

67 Inhibition of complex I of the mitochondrial electron transport chain activated AMPK and inhibited Kv

68 s shown that disruption of the mitochondrial electron transport chain activates a G1-S checkpoint as

69 tion (BNIP3 and NDUFA4L2), and mitochondrial electron transport chain activity (cytochrome oxidase 4.

70 Biochemically mutant mice showed impaired electron transport chain activity and accumulated autoph

71 n a reduction in mitochondrial RNAs, reduced electron transport chain activity, and reduced ATP level

72 o our hypothesis, skeletal muscle endurance, electron transport chain activity, and voluntary wheel r

73 IMM constriction requires electron transport chain activity.

74 ion in mitochondria, including modulation of electron transport chain activity.

75 to limit HMG-CoA-derived MGC and protect the electron transport chain against inhibitory compounds.

76 anonical tricarboxylic acid (TCA) cycles and electron transport chains, although the roles differ bet

77 due to a coupling between the photosynthetic electron transport chain and a plastidial hydrogenase.

78 ate that mSOF activity in muscle depended on electron transport chain and adenine nucleotide transloc

79 s the activity of both complex II/III of the electron transport chain and ATP synthase.

80 capacity and efficiency of the mitochondrial electron transport chain and ATP synthesis.

81 synthesis while maintaining a redox-balanced electron transport chain and avoiding excessive reactive

82 ylococcus aureus typically lack a functional electron transport chain and cannot produce virulence fa

83 ce of redox reactions that are coupled to an electron transport chain and convert the colorless 15-ci

84 a are known primarily as the location of the electron transport chain and energy production in cells.

85 is critically dependent on the mitochondrial electron transport chain and oxidative phosphorylation m

86 idation state of NAD(H) and the hemes of the electron transport chain and oxygen consumption within i

87 itochondria including the citric acid cycle, electron transport chain and ROS production and scavengi

88 ifically for components of the mitochondrial electron transport chain and the chloroplastic photosynt

89 ROS production is primarily mediated by the electron transport chain and the proton motive force con

90 alternative is that the lack of a functional electron transport chain and the resulting reduction in

91 dehydrogenase, an important component of the electron transport chain and the tricarboxylic acid cycl

92 ), two important factors of the mitochondria electron transport chain and the tricarboxylic acid cycl

93 ited by agents that target the mitochondrial electron transport chain and, conversely, loss of mitoch

94 on ferredoxin reduced by the photosynthetic electron transport chain and, thus, on light, and the NA

95 RNA, blocks the assembly of complex I in the electron transport chain, and causes an arrest in embryo

96 c oxidase (CcO) as part of the mitochondrial electron transport chain, and it also participates in ty

97 ired for the tricarboxylic acid (TCA) cycle, electron transport chain, and oxidative phosphorylation,

98 ation is given by phosphorylation subsystem, electron transport chain, and substrate dehydrogenation

99 O-A knockdown (KD) on ATP, oxidative stress, electron transport chain, and survival following exposur

100 oxidase, xanthine oxidase, the mitochondrial electron transport chain, and uncoupled endothelial nitr

101 d restoration of a functional photosynthetic electron transport chain appears to be linked to the bio

102 Recently, complex II of the electron transport chain appears to be more important th

103 l protein import show that components of the electron transport chain are imported by distinct pathwa

104 s containing complexes I, III, and IV of the electron transport chain are now regarded as an establis

105 s of membrane potential or inhibition of the electron transport chain, as confirmed by addition of ca

106 SIRT3 rescued the IR-induced blockade of the electron transport chain at the level of complex III, at

107 reduced by IP(3)R inhibition, mitochondrial electron transport chain block, antioxidant treatment, a

108 Inhibition of the mitochondrial electron transport chain by antimycin A resulted in an i

109 x I) plays a central role in the respiratory electron transport chain by coupling the transfer of ele

110 Methylene blue potentiates the electron transport chain by shuttling elections from NAD

111 bility of our method by assembling a minimal electron transport chain capable of adenosine triphospha

112 Mitochondrial respiratory complexes of the electron transport chain (CI, CIII, and CIV) can be asse

113 olic networks in tumour cells, including the electron transport chain, citric acid cycle, fatty acid

114 e-S cluster biosynthesis, leading to reduced electron transport chain complex (ETC) activity and mito

115 Moreover, electron transport chain complex (I, V) decrease in FECD

116 active oxygen species (ROS), flow cytometry, electron transport chain complex assays, and hemocyte is

117 trium and cervix function, and mitochondrial electron transport chain complex enzymatic activities we

118 oxidative stress and decreased mitochondrial electron transport chain complex I activity in adrenal m

119 s of riboflavin, downstream metabolites, and electron transport chain complex I activity.

120 Electron transport chain complex I and complex II activi

121 In Escherichia coli, granzymes cleave electron transport chain complex I and oxidative stress

122 d skeletal muscle mitochondrial respiration, electron transport chain complex I dysfunction, as well

123 ess is negatively regulated by mitochondrial electron transport chain complex I through both cell int

124 ration rate that is likely due to defects in electron transport chain complex I.

125 t shock protein 90, binds and stabilizes the electron transport chain Complex II subunit succinate de

126 ble fumarate reductase and the mitochondrial electron transport chain complex II.

127 the mitochondrial genome, ultimately causing electron transport chain complex IV remodeling and mitoc

128 f mtDNA; however, the amount and activity of electron transport chain complex IV were significantly d

129 capacity, ATP production, and activities of electron transport chain complexes (C) I and CIV but not

130 sfunction resulting from failure to assemble electron transport chain complexes and altered the expre

131 Electron transport chain complexes are downregulated, po

132 Mitochondrial electron transport chain complexes are organized into su

133 e process of dismantling their mitochondrial electron transport chain complexes as they adapt to anae

134 drial mass and differential contributions of electron transport chain complexes I and II to respirati

135 stained hypoxia also decreased expression of electron transport chain complexes I and IV and UCP3 lev

136 r by inhibitors of pyruvate dehydrogenase or electron transport chain complexes I or III, increased g

137 e in cell cultures, enzyme activities of the electron transport chain complexes in isolated mitochond

138 is primarily limited by the activity of the electron transport chain complexes rather than by a limi

139 As a result, electron transport chain complexes show significant redu

140 ngly, although subunits of the mitochondrial electron transport chain complexes were reduced at the p

141 Furthermore, assembled, electron transport chain complexes were significantly mo

142 sphorylation, dysfunctional mitochondria and electron transport chain complexes, and depleted ATP sto

143 complex (TRiC) chaperonin, the mitochondrial electron transport chain complexes, and the circadian cl

144 he enzymatic activities of the mitochondrial electron transport chain complexes.

145 re we show a role for the dysfunction of the electron transport chain component cytochrome c oxidase

146 ndicated that Pitx2 activated genes encoding electron transport chain components and reactive oxygen

147 ive capacity and abundant expression of both electron transport chain components and uncoupling prote

148 Chlorate-specific transcription of electron transport chain components or the CRI was not o

149 nt TCP/TRiC/CCT chaperonin and mitochondrial electron transport chain components.

150 been linked to flavin photoreduction via an electron transport chain comprising three evolutionarily

151 The mitochondrial electron transport chain consists of individual protein

152 tream enzyme that is necessary for efficient electron transport chain coupling and energy production

153 nergetic efficiency as evidenced by enhanced electron transport chain coupling using multiple substra

154 hondrial superoxide levels and mitochondrial electron transport chain damage, and that addition of Mi

155 Our results show that mitochondrial electron transport chain defect initiates a retrograde s

156 s of AIF in fibroblasts led to mitochondrial electron transport chain defects and loss of proliferati

157 euron-specific mouse models of mitochondrial electron transport chain deficiencies involving defects

158 hat mt-cpYFP flash events reflect a burst in electron transport chain-dependent superoxide production

159 id metabolism, as well as the first complete electron transport chain described for a member of the C

160 ich are involved in energy generation by the electron transport chain, detoxification of host immune

161 aging theories and implicates mitochondrial electron transport chain dysfunction with subsequent inc

162 Campylobacter jejuni harbors a branched electron transport chain, enabling respiration with diff

163 I represses genes critical for mitochondrial electron transport chain enzyme activity, oxidative stre

164 Electron transport chain (ETC) activity generates an ele

165 A decline in electron transport chain (ETC) activity is associated wi

166 cies generation, but at the cost of impaired electron transport chain (ETC) activity.

167 cations of Krebs cycle components as well as electron transport chain (ETC) alterations.

168 Stat3) where it controls the activity of the electron transport chain (ETC) and mediates Ras-induced

169 ae morphology, fusion in TM cells configures electron transport chain (ETC) complex associations favo

170 ns with the mRNAs encoding the mitochondrial electron transport chain (ETC) complex I as well as hund

171 as well as significantly decreased (40%-50%) electron transport chain (ETC) complex I, II, IV, V, and

172 abundance of mitochondria and high levels of electron transport chain (ETC) complexes within these mi

173 Mitochondrial electron transport chain (ETC) disorders cause severe ne

174 The mitochondrial electron transport chain (ETC) enables many metabolic pr

175 High glucose levels or mutations affecting electron transport chain (ETC) function inhibited amino

176 l (Mit) mutants have disrupted mitochondrial electron transport chain (ETC) functionality, yet, surpr

177 The Mycobacterium tuberculosis (Mtb) electron transport chain (ETC) has received significant

178 ate 12 different models of the mitochondrial electron transport chain (ETC) in Arabidopsis thaliana d

179 or lifespan extension from inhibition of the electron transport chain (ETC) in Caenorhabditis elegans

180 kinases bound complex I of the mitochondrial electron transport chain (ETC) in spermatogenic and in c

181 ndrial encoded subunits of the mitochondrial electron transport chain (ETC) in xenocybrid cells compr

182 Using uncoupled respiration as a marker of electron transport chain (ETC) integrity, the nephrotoxi

183 ies, mitochondrial respiration driven by the electron transport chain (ETC) is significantly reduced.

184 at donate electrons at specific sites in the electron transport chain (ETC) is unchanged.

185 al and specific genetic requirements for the electron transport chain (ETC) longevity pathway.

186 hondria undergo fragmentation in response to electron transport chain (ETC) poisons and mitochondrial

187 al modeling, we found that the mitochondrial electron transport chain (ETC) responds to oxygen level

188 mutations in the citric acid cycle (CAC) or electron transport chain (ETC) that disable normal oxida

189 ction through the coupled integration of the electron transport chain (ETC) with oxidative phosphoryl

190 I) photodamage by keeping the photosynthetic electron transport chain (ETC), and hence PSII reaction

191 evealed that among components of the aerobic electron transport chain (ETC), only genes involved in t

192 CoQ10 is an essential component of the electron transport chain (ETC), where it shuttles electr

193 ts actions on complex I of the mitochondrial electron transport chain (ETC).

194 EKO)), which induces loss of function of the electron transport chain (ETC).

195 proteins in complexes I, III, and IV of the electron transport chain (ETC).

196 of respiratory quiescence by remodeling the electron transport chain (ETC).

197 (TCA) cycle, and ATP synthesis powered by an electron transport chain (ETC); instead, they produce AT

198 ochrome c oxidase (COX) in the mitochondrial electron transport chain (ETC); suppression of COX activ

199 eria in which photosynthetic and respiratory electron transport chains (ETC) share components.

200 that placental hypoxia alters mitochondrial electron transport chain (ETS) function, and sought to i

201 (II)Phthalocyanines were linked to different electron-transport chains featuring pairs of electron ac

202 y improved complex II/III respiration of the electron transport chain following 24 hours of cold stor

203 me is essential for processing heme into the electron transport chain for use as an electron acceptor

204 Cytochrome P450 is part of an electron transport chain found in the endoplasmic reticu

205 nted here suggest that the first part of the electron transport chain from formate to fumarate or Cl-

206 kely encode the identified components of the electron transport chain from formate to fumarate or Cl-

207 anding of the structural organization of the electron transport chain from the original idea of a com

208 y, dysregulation of reactive oxygen species, electron transport chain function and calcium homeostasi

209 radient to generate ATP and interfering with electron transport chain function can lead to the delete

210 However, respiratory coupling and electron transport chain function were normal in ucp4 mi

211 l dysfunction in vivo by restoring defective electron transport chain function, collapse of transmemb

212 main of Ups2p maintains proper mitochondrial electron transport chain function, respiratory competenc

213 plexes of the photosynthetic and respiratory electron transport chains function in the intracellular

214 types, while copy number alterations in the electron transport chain gene SCO2, fatty acid uptake (C

215 ytes; however, no changes in nuclear-encoded electron transport chain gene transcripts or mtDNA copy

216 Changes in expressions of the electron transport chain genes were found in HD patients

217 We measured the mRNA levels of electron transport chain genes, and mitochondrial struct

218 n is detrimental, partial suppression of the electron transport chain has been shown to extend C. ele

219 sm to maintain a certain redox status of the electron transport chain, hence allowing proper photosyn

220 decreases the activity of complex IV of the electron transport chain, however without affecting cell

221 PINK1, as well as chemical inhibition of the electron transport chain, impaired lysosomal activity an

222 connects the tricarboxylic acid cycle to the electron transport chain in mitochondria and many prokar

223 is a required component of the ATP-producing electron transport chain in mitochondria.

224 lex influenced better phosphorylation in the electron transport chain in the case of MnNP-treated chl

225 tion, we explored whether restoration of the electron transport chain in this organism also affected

226 Therefore, the lack of functional electron transport chains in SCV S. aureus and wild-type

227 The electron transport chains in the membranes of bacteria a

228 The mitochondrial electron transport chain includes an alternative oxidase

229 ergy generation via select components of the electron transport chain, including cytochrome bo oxidas

230 ereas other components of the photosynthetic electron transport chain, including photosystem I, were

231 Redox cycling, mitochondrial DNA damage and electron transport chain inhibition have been identified

232 nsitivity of IDH1-mutant cells to hypoxia or electron transport chain inhibition in vitro.

233 Electron transport chain inhibition is the main pathway

234 Finally, potassium cyanide, an electron transport chain inhibitor, briefly stops growth

235 the actual rates observed in the absence of electron transport chain inhibitors, so maximum capaciti

236 e and calcium, and the presence of different electron transport chain inhibitors.

237 erefore, it is likely that relaxation in the electron transport chain is not responsible for the asym

238 e function of Opa1 in the maintenance of the electron transport chain is physiologically relevant in

239 (CI), a protein complex of the mitochondrial electron transport chain, is a target for oxidant-induce

240 also known as complex V of the mitochondrial electron transport chain, is the main cellular energy-ge

241 oxidase (COX) is the terminal enzyme of the electron transport chain, made up of 13 subunits encoded

242 ons were observed in proteins throughout the electron transport chain membrane complexes, ATP synthas

243 on of the terminal step of the mitochondrial electron transport chain (mETC).

244 in model organisms has revealed roles in the electron transport chain, mitochondrial protein homeosta

245 e methods severely disrupt the mitochondrial electron transport chain, mtDNA-depleted cells still mai

246 model of the reactions in the photosynthetic electron transport chain of C3 species.

247 serves as the last enzyme in the respiratory electron transport chain of eukaryotic mitochondria.

248 dase, the terminal enzyme in the respiratory electron transport chain of mitochondria, from hippocamp

249 Disruption of the electron transport chain of S. aureus genetically (hemB

250 fNDH2), a dehydrogenase of the mitochondrial electron transport chain of the malaria parasite Plasmod

251 to perturbations in mitochondrial mass, the electron transport chain, or emission of reactive oxygen

252 RT5-treated membrane proteins pointed to the electron transport chain, particularly Complex I, as bei

253 c oxidase (CcO), known as complex IV of the electron transport chain, plays several important roles

254 days of voluntary wheel running by measuring electron transport chain protein content, enzyme activit

255 number and decreased steady-state levels of electron transport chain proteins in the brain.

256 analysis revealed downregulation of several electron transport chain proteins with aging, and this w

257 ndrial architecture, increased expression of electron transport chain proteins, and depletion of fat

258 man AML, treatment with ddC decreased mtDNA, electron transport chain proteins, and induced tumor reg

259 igh-confidence approach, we demonstrate that electron transport chain proteins, especially the matrix

260 (TCA) cycle oxidoreductive enzymes and most electron transport chain proteins, except CydAB, were ma

261 d the number of mitochondria and doubled the electron transport chain proteins, uncoupling protein 1,

262 lso known as complex II of the mitochondrial electron transport chain, providing support for the bifu

263 d either endogenously, through mitochondrial electron transport chain reactions and nicotinamide aden

264 lfur cluster proteins, depression of aerobic electron transport chain respiration, massive mitochondr

265 T cells by interfering with the formation of electron transport chain respiratory supercomplexes.

266 ntially regulated depending upon the type of electron transport chain/respiratory chain deficiency.

267 hanges after inhibition of the mitochondrial electron transport chain, revealed a fast and dynamic ad

268 , which also hosts the final cofactor in the electron transport chain, riboflavin.

269 el presented here explores the modulation of electron transport chain ROS production for state 3 and

270 tioxidant Mito-Tempo and an inhibitor of the electron transport chain, rotenone, also effectively pre

271 l changes, including decreased expression of electron transport chain subunit genes and impaired ener

272 Two atypical mitochondrial electron transport chain subunits (Ndufa4l2 and Cox4i2)

273 way, ion channels and atypical mitochondrial electron transport chain subunits.

274 ctors, mitochondrial ribosomal proteins, and electron-transport chain subunits.

275 groups including genes for the mitochondrial electron transport chain, tetrapyrrole biosynthesis, car

276 erium woodii has a novel Na(+)-translocating electron transport chain that couples electron transfer

277 The genome encoded an aerobic respiratory electron transport chain that included NADH dehydrogenas

278 iological data suggest that Aer monitors the electron transport chain through the redox state of its

279 In order for the electron transport chain to function, electron shuttling

280 The electrons can also enter the electron transport chain to produce adenosine triphospha

281 ld and included nearly all components of the electron transport chain, tricarboxylic acid cycle, and

282 Inhibition of complex I of the mitochondrial electron transport chain using phenformin activated AMPK

283 that can be transferred to the mitochondrial electron transport chain via the electron transfer flavo

284 as found that complex I of the mitochondrial electron transport chain was affected adversely with inc

285 ex IV but not complex II activity within the electron transport chain was found only in T2DN(mtFHH),

286 are critical components of the mitochondrial electron transport chain, we hypothesized that reduced r

287 of electron fluxes along the photosynthetic electron transport chain, we overexpressed a minor pea (

288 In contrast, neither sites 1 nor 4 of the electron transport chain were both necessary and essenti

289 activities of complexes of the mitochondrial electron transport chain were decreased in mtErbB2-overe

290 (0) cells, which are devoid of a functioning electron transport chain, were used to demonstrate that

291 on ferredoxin reduced by the photosynthetic electron transport chain, which fuels reducing power to

292 ation, electrons leak from the mitochondrial electron transport chain, which is captured by molecular

293 l proteins but also of other proteins of the electron transport chain, which led to an increase in th

294 t also maintain the iron-rich photosynthetic electron transport chain, which most likely evolved in t

295 r genes, all components of the mitochondrial electron transport chain, which show significant loss of

296 e nonetheless sensitive to inhibitors of the electron transport chain, which supports clinical recomm

297 nic cells occurs mainly at complex II of the electron transport chain with a down-regulation of the s

298 nction with an uncoupler or interrupting the electron transport chain with cyanide (CN(-)) alters ER

299 nt glioma cells, 2) remodeling of the entire electron transport chain with significant decreases of c

300 pecies (ROS) generated as by-products of the electron transport chain within mitochondria significant