ライフサイエンスコーパス: electron-dense

1 ans, the typical presynaptic terminal has an electron-dense active zone surrounded by synaptic vesicl

2 i along the apical surface and intercellular electron-dense adhesive junctions that resemble adherens

3 d the accumulation of large, well-demarcated electron-dense aggregates but no characteristic membrane

4 is present in subendothelium in the form of electron-dense aggregates having diameters varying betwe

5 e: Most notably, the presence of cytoplasmic electron-dense aggregates in podocytes.

6 irions that contain "eccentric condensates," electron-dense aggregates located outside seemingly empt

7 d Lon-knockdown cells is the accumulation of electron-dense aggregates within mitochondria.

8 duced reserpine-sensitive dissipation of the electron-dense aggregates, compatible with the idea that

9 th some particles containing multiple small, electron-dense aggregates.

10 ectron microscopical studies showed that the electron-dense aggregrates in gastrin cell secretory gra

11 ; however, the cores typically appeared less electron dense and more rod shaped than WT virions.

12 1(+)MHC-II(+) compartments are predominantly electron dense and, in these cells, empty MHC-II molecul

13 bacteria in membrane-bound vacuoles and both electron-dense and electron-lucent forms.

14 um containing linear lamellae of alternating electron-dense and electron-lucent material, reflecting

15 on, the rER- and plasma-membrane pockets are electron dense, and sesquiterpenes are detectable only i

16 Arp2/3 form apical actin-rich microvilli and electron-dense apical junctions.

17 es and subsequently becomes localized in the electron-dense area of the apical complex.

18 ochondria from Shh-treated neurons were more electron-dense, as revealed by electron microscopy, and

19 on the sulfonamide nitrogen that contain an electron dense atom, such as a fluorine, are favored in

20 partial loss of microvilli, and retention of electron-dense biliary material.

21 cells in pn demonstrated an accumulation of electron dense bodies.

22 on of CryAB(R120G) leads to the formation of electron-dense bodies characteristic of the DRMs and ide

23 ticles are visible by electron microscopy as electron-dense bodies in the cytoplasm.

24 propose that these distinctive Ro-associated electron-dense bodies may represent structure(s) importa

25 The presence of immunogold-labeled electron-dense bodies was correlated with the presence o

26 Instead, novel round, electron-dense bodies were found associated with the vir

27 there was an accumulation of membrane-coated electron-dense bodies, crescents, and immature virus par

28 reviously unreported nuclear and cytoplasmic electron-dense bodies.

29 ze predominantly to the cell poles and to an electron-dense body in the cytoplasm.

30 Similar to the vertebrate organization, electron-dense cell networks penetrated from the outer l

31 The vertebrate distinction between electron-dense cells in the most external connective tis

32 uclear volume and an increase in the size of electron-dense chromatin bodies; neither of these morpho

33 Assembly into an electron-dense coat then helps in budding off membrane t

34 composed of small ring-shaped profiles with electron-dense coats.

35 most similar to wild-type (WT) virions with electron-dense, conical cores.

36 enging because of difficulties in delivering electron-dense contrast agents to specific subcellular t

37 approximately 7 nm external diameter and an electron dense core, and to form channels of 50picoSieme

38 a polar terminal organelle having a central electron-dense core and adhesin-related proteins cluster

39 inchworm-like conformational changes of its electron-dense core are leveraged against a cytoplasmic

40 rizing the physicochemical properties of the electron-dense core atrial gland vesicles from Aplysia c

41 ludes determination of the dimensions of the electron-dense core by transmission electron microscopy

42 rupted CA-SP processing, cDNA synthesis, and electron-dense core formation.

43 ytadherence, and, in some cells, an atypical electron-dense core in the attachment organelle.

44 his effect was associated with a loss of the electron-dense core of G cell secretory vesicles.

45 t that HMW2 is the defining component of the electron-dense core of the terminal organelle.

46 complex membrane-bound cell extension is an electron-dense core of two segmented rods oriented longi

47 plasma cell is defined by the presence of an electron-dense core that appears as paired, parallel bar

48 dase E, chromogranin C, and IL-2, and had an electron-dense core typical of secretory vesicles.

49 l questions regarding the composition of the electron-dense core, the means by which the terminal org

50 e mycoplasma cell possesses a characteristic electron-dense core.

51 ll extension containing an intracytoplasmic, electron-dense core.

52 a single perimetral membrane surrounding an electron-dense core.

53 ane-bound cell extension distinguished by an electron-dense core.

54 ental cycle, transitioning between a smaller electron dense-cored cell (DC), which has a dense nucleo

55 The electron-dense cores of regulated secretory granules in

56 leavage of the SP-NC junction, production of electron-dense cores, and cDNA synthesis but blocked ret

57 ers of these particles that accumulate small electron-dense cores.

58 e outer integument of the seed coat lost the electron-dense cuticle layer at its surface and displaye

59 dense line of myelin sheaths to accommodate electron dense cytoplasm derived from the oligodendrogli

60 ircular or oval in outline, while those with electron-dense cytoplasm (dark cells) had an irregular o

61 e most common of which is an accumulation of electron-dense cytoplasm within some sheaths, a change w

62 the Src-related kinases are associated with electron-dense cytoplasmic domains and plasma membrane d

63 form within specific PAS-diastase-resistant electron-dense cytoplasmic granules.

64 Large electron-dense cytoplasmic inclusions and clusters of sc

65 protein determinants, which are assembled in electron-dense cytoplasmic structures known as germ or p

66 CT were undergoing electron dense degeneration but still sometimes formed a

67 ules evolved from electron lucent with small electron dense deposits at E15 to more electron dense gr

68 ays an irregular morphology and round, dark, electron dense deposits that do not give rise to a diffr

69 h full house immunofluorescence and multiple electron dense deposits.

70 ly in regions corresponding to subepithelial electron dense deposits.

71 inflammatory renal disease characterized by electron-dense deposits and complement C3 on the glomeru

72 Electron microscopy revealed finely granular electron-dense deposits coating the surfaces of frayed d

73 es of renal lesions revealed the presence of electron-dense deposits in affected arteries, and IgG, I

74 from individuals with Alzheimer's disease as electron-dense deposits located exclusively in the cytop

75 ngial and subendothelial immune complex-type electron-dense deposits.

76 In addition, small electron-dense dot-like structures measuring approximate

77 e inhibitors caused a marked accumulation of electron-dense double-membrane-limited AVs, containing c

78 1-deficient mice were next perfused with the electron dense dye Ruthenium Red.

79 By contrast, electron-dense endosomes that could be confused with ALI

80 unique 15-protofilament microtubules and an electron-dense extracellular matrix have been proposed t

81 QDs are both fluorescent and electron dense, facilitating their use for correlated mi

82 In addition to active site binding by Cm, an electron-dense feature resembling the enzyme's product i

83 Both electron-dense features demonstrated the presence of gad

84 An electron-dense filamentous material, detected within ext

85 on of crescent membranes on the periphery of electron-dense globular masses but few mature particles.

86 iferation or necrosis by light microscopy or electron-dense glomerular basement membrane deposits by

87 ol with a relatively small (0.8 nm diameter) electron dense gold cluster compound, undecagold monoami

88 heart showed aberrant intrasarcoplasmic and electron-dense granular filamentous aggregates that were

89 , the association of crescent membranes with electron-dense granular material, is perturbed when expr

90 ing tubular elements were separated from the electron-dense granular viroplasm, which accumulated in

91 L protein is required for the association of electron-dense, granular, proteinaceous material with th

92 he finding that sporozoites have a different electron-dense-granule composition, we have now found th

93 small electron dense deposits at E15 to more electron dense granules with complex patterns of interna

94 Thus, CgA-expressing A35C cells showed electron-dense granules approximately 180-220 nm in diam

95 Furthermore, the presence of numerous electron-dense granules around the phagosomes indicated

96 imal kingdom is the presence of perinuclear, electron-dense granules called nuage.

97 Centriolar satellites are numerous electron-dense granules dispersed around the centrosome.

98 mmunoreactivity localized to the cytoplasmic electron-dense granules in ASPS.

99 roscopy analysis revealed a higher number of electron-dense granules in Ctr2(-/-) mast cells than in

100 O-gold-affinity method detected histamine in electron-dense granules of mast cells in control and inj

101 vacuole of plants (tonoplast) and the small electron-dense granules of some parasites (acidocalcisom

102 vealed neurons containing distinctive large, electron-dense granules, which could reliably be used to

103 appeared ultrastructurally as intracellular electron-dense granules.

104 n developing macronuclei, Pdd1p localizes to electron-dense, heterochromatic structures that contain

105 ed luminal and abluminal vesicles containing electron-dense horseradish peroxidase-reaction product w

106 argely intact in the mid-SC, but replaced by electron-dense (hydrophilic) clefts (lacunae) that expan

107 the presence of LDI-1 WW, VLPs were found in electron-dense inclusion bodies in the cytoplasm of tran

108 resulted in a rapid massive accumulation of electron-dense inclusion bodies in the RPE.

109 koid lumen, and differential accumulation of electron-dense inclusion bodies.

110 rplastic mitochondria, some of which contain electron dense inclusions.

111 children have (1) swollen mitochondria with electron-dense inclusions and abnormal inner-membrane mo

112 tory areas of the cytoplasm contained large, electron-dense inclusions, some of which had partially c

113 Both types of cell contained highly electron-dense inclusions, which probably represent phag

114 ns showed markedly thickened endothelium and electron-dense interstitial deposits.

115 arance, associated with collagen fibrils and electron-dense intracellular fragments of collagen fibri

116 alent activation of C3 convertase and highly electron-dense intramembranous deposits.

117 Ultrastructural analysis revealed both electron-dense intranuclear deposits and cytoplasmic inc

118 odeling of drug-enzyme interactions, but the electron-dense iodine atom of the inhibitor has been una

119 energy-dispersive X-ray spectroscopy showed electron-dense iron-containing aggregates within the mag

120 These contrast with the electron-dense knob protrusions expressed at the surface

121 ESEM) based on intra-vesicular generation of electron-dense labeling in axonal boutons.

122 casional short crescent-shaped membranes and electron-dense lacy structures.

123 mediated contacts displayed a characteristic electron-dense layer between the ER and the PM.

124 lved in the composition or maintenance of an electron-dense layer between the outer cell wall and the

125 lls by electron microscopy revealed a thick, electron-dense layer surrounding the opaque cells that w

126 These aggregated capsids were immersed in an electron-dense layer that appeared to be tegument.

127 composed of a spiral structure coated by an electron-dense layer underlying the knob membrane.

128 lysis revealed that although sarcomeres with electron dense M- and Z-bands are present in muscle fibe

129 This electron-dense marker uniformly decorated the cell membr

130 and in those hemorrhaged and given IL-6, the electron-dense marker, administered intravenously, could

131 e stained infected cells with fluorescent or electron-dense markers specific for organelles and exami

132 Here we developed genetically-encoded, electron-dense markers using miniSOG.

133 itional electron microscopy studies revealed electron dense material in the t-tubules within the musc

134 rosis, lipid accumulation, and deposition of electron dense material throughout the glomeruli.

135 be mechanically reinforced by an intervening electron-dense material (EDM).

136 that immature virus particles and masses of electron-dense material accumulated in the absence of an

137 dot2 mutants show excess electron-dense material accumulating near SPBs, which we

138 ifically in scolopale cells causes abnormal, electron-dense material accumulation in the scolopale sp

139 Electron-dense material and midbodies are both absent fr

140 opy shows that plus-end foci are coated with electron-dense material and resemble similar foci in mon

141 ed that the virus particles were coated with electron-dense material but not aggregated at neutralizi

142 tron microscopy revealed the accumulation of electron-dense material in the mesangial matrix and age-

143 the centrosomal area in association with the electron-dense material surrounding centrioles.

144 bing within chlamydial inclusions, and (iii) electron-dense material surrounding inclusions.

145 iary root with a pronounced cross-banding of electron-dense material that should be important for the

146 es are lined on the cytoplasmic side with an electron-dense material to which is attached a monolayer

147 characterized by the deposition of abnormal electron-dense material within the glomerular basement m

148 d irregularly branching, pleomorphic, highly electron-dense material, resembling the hyaline structur

149 t of the central pair complex by accumulated electron-dense material.

150 endoplasmic reticulum, coated vesicles, and electron-dense material.

151 agmoplast MTs overlapped and were bridged by electron-dense materials in Arabidopsis thaliana.

152 Protein aggregates appeared as clumps of electron-dense materials that stained heavily for ubiqui

153 ytoplasm, where they were embedded within an electron-dense matrix material.

154 ctron microscopy revealed bacteria within an electron-dense matrix, similar to pneumococcal biofilms

155 s of structural definitions and reduction in electron-dense matrix.

156 The filopodial tips contain a heavy electron-dense matter that appears to attract the synapt

157 lonRI and GM1 causes their redistribution to electron-dense membrane patches independently of each ot

158 Most presynaptic termini contain electron-dense membrane structures, often referred to as

159 ral studies showed numerous larger-sized and electron-dense mitochondria in nGD cerebral cortical neu

160 observed under LM colocalises well with the electron dense nanoparticle observed in EM.

161 The presence of electron-dense nanoparticles in vascular pericytes in th

162 r, transmission electron microscopy revealed electron-dense nanoparticles only in the neuroglia of no

163 e germ cells--the RNF17 granule, which is an electron-dense non-membrane bound spherical organelle wi

164 hat the punctate foci containing SREBP-2 are electron-dense nuclear bodies, similar or identical to s

165 Labeled HA coincided with electron-dense, often noncircular membrane patches.

166 is a component of polar granules and nuage, electron-dense organelles characteristic of the germline

167 Transmission electron microscopy showed the electron-dense particle diameter to be 50-700 nm, sugges

168 ectron microscopy indicated that although no electron-dense particles at any stage of assembly were s

169 rthermore, Mx Hsp16.6 was detected in highly electron-dense particles in heat-shocked cells by immuno

170 ormation and cytoplasmic vacuoles containing electron-dense particles, whereas ALA+deferoxamine treat

171 oscopy, NADPH-d reaction product appeared as electron-dense particles.

172 lectron microscopy showed an accumulation of electron-dense patches of actin and strikingly altered m

173 s visualized by LM correspond to homogeneous electron-dense perinuclear inclusion bodies (up to 1.4 m

174 When the drug is removed these proteins form electron-dense plaques which we term staples.

175 nstrated NaV1.6-positive staining within the electron dense podosome rosette structure.

176 4) The electron-dense pre- and postsynaptic apposition is expan

177 l organization, commonly containing a single electron-dense presynaptic density surrounded by a clust

178 obenzidine to convert the dye signal into an electron-dense product.

179 Electron-dense products were located almost exclusively

180 The electron-dense profiles of these contacts were easily id

181 The hallmark of most AZs is an electron-dense projection (DP) surrounded by SVs.

182 e center of active zones, we found elaborate electron-dense projections physically connecting vesicle

183 rder characterized by muscle dysfunction and electron-dense protein accumulations (nemaline bodies) i

184 This created an electron-dense reaction product that could be visualized

185 ternalized FM1-43 was photoconverted into an electron-dense reaction product.

186 showed that TlpC localized to a cytoplasmic electron-dense region.

187 beyond a particular concentration and offer electron-dense regions at the center of the vesicle.

188 Moreover, the electron-dense regions containing these two enzymes were

189 are the appropriate size to account for the electron-dense regions in amyloid protofilaments.

190 M in infected cells and (ii) the presence of electron-dense regions in the INM, representing nucleoca

191 Particle buds and electron-dense regions of plasma membrane were observed

192 um and tonoplast in these cells, and also in electron-dense regions that are, as yet, unidentified.

193 l-Vasicine is a quinazoline alkaloid with an electron dense ring and additional functionalities in it

194 by increasing the spacing between the inner electron-dense ring and the VLP membrane.

195 uter mitochondrial membranes are packed with electron-dense RNA fibrils and their volumes are closely

196 act allergy display progressive secretion of electron-dense secretory granule contents and retention

197 We also describe a population of small electron-dense SGL cells, which we call type D cells and

198 ical core shell and instead contained a thin electron-dense shell about 10 nm underneath the virion m

199 erical, acentric core and a crescent-shaped, electron-dense shell lying just inside the viral membran

200 gradient ultracentrifugation were spherical, electron dense, small (< 100 nm in diameter) particles,

201 ted with AcMNPV p10 fibrillar structures and electron-dense spacers that are precursors of the polyhe

202 ntly associated with mitochondria and a less electron-dense sphere of similar size that appears to be

203 ic structures in D. melanogaster, are evenly electron-dense spheres 1.5 microm in diameter (herein te

204 defined core structures, there were numerous electron-dense, spherical particles.

205 probably corresponds to the vacuole, and an electron dense spheroidal body, 300-500 nm in diameter,

206 is separated from the host cell by a unique electron-dense structure of unknown composition.

207 The nuage is a hazy electron-dense structure unique to germ cells and is enr

208 ae, Rubisco is localized to the pyrenoid, an electron-dense structure within the chloroplast.

209 These electron-dense structures are conserved across species,

210 ned large mitochondria with lamellar-shaped, electron-dense structures at the ultrastructural level.

211 h internal eliminated sequences in transient electron-dense structures in the developing macronucleus

212 Inclusions appear as distinct granular electron-dense structures in the nucleus by immunoelectr

213 on microscopy revealed LANDs to be globular, electron-dense structures morphologically distinct from

214 Ultrastructurally, PS bodies corresponded to electron-dense structures of 150-300 nm diameter and res

215 sediment by electron microscopy, we observed electron-dense structures resembling chlamydial organism

216 ic protein Bruchpilot, calcium channels, and electron-dense T bars are concentrated at a fraction of

217 les were near the plasma membrane, sometimes electron-dense "tethers" appeared between the vesicle an

218 chondria with swollen matrices that are less electron-dense than matrices in normal mitochondria.

219 cells caused the walls of variants to become electron-dense, thin, and sinuous.

220 acellular matrix of the bmp mutant contained electron-dense, thread-like structures that were also pr

221 mony (TBSb), a compound that is sufficiently electron dense to have been observed to occupy the cavit

222 GBM permeability to the electron-dense tracer ferritin was dramatically elevated

223 stinal microvasculature, mice were given the electron-dense tracer horseradish peroxidase (HRP) after

224 robe analysis to monitor permeability to the electron-dense tracer lanthanum.

225 derivatives, which catalyze production of an electron-dense tracer, to genetically identify neurons,

226 PLT production and is distributed to a novel electron-dense tubular system-related compartment we hav

227 lved ribosomal dissociation and a late-onset electron-dense type displaying nuclear pyknosis and seve

228 detected only in vacuoles distinct from the electron-dense vacuoles and other organelles.

229 nt 3- or 2-fold increase in potassium in the electron-dense vacuoles and the iron-rich vacuoles, resp

230 re of the vacuoles and demonstrated that the electron-dense vacuoles correspond to what were describe

231 pyroantimoniate-osmium technique and as the electron-dense vacuoles observed in whole unfixed parasi

232 These results indicate that the electron-dense vacuoles of C. reinhardtii are very simil

233 X-ray microanalysis of the electron-dense vacuoles or polyphosphate bodies of C. re

234 that the heaviest (pellet) fraction contains electron-dense vacuoles rich in phosphorus, calcium, and

235 Purification of the electron-dense vacuoles using iodixanol density gradient

236 and X-ray microanalysis as acidocalcisomes (electron-dense vacuoles).

237 In isolated electron-dense vacuoles, PP(i)-driven proton translocati

238 ss of PfPM2, and an abundant accumulation of electron-dense vesicles in the digestive vacuole was obs

239 fusion complexes, which are characterized by electron-dense vesicles paired on either side of the fus

240 fusion, possibly by mediating fusion of the electron-dense vesicles to the plasma membrane.

241 reased insoluble TDP-43, as well as enlarged electron-dense vesicles, lipofuscin accumulation, finger

242 granules, but there was an abundance of non-electron-dense vesicles.

243 t were ciliated and contained numerous large electron-dense vesicles.

244 P signal can be visualized as photoconverted electron-dense vesicles.

245 II IN mutations, block the formation of the electron-dense viral core and inhibit reverse transcript

246 inducer showed virus factories with abnormal electron-dense viroplasms and intermediate density regio

247 In the absence of A14, electron-dense virosomes and distinct clusters of small

248 i), crescents appear at the periphery of the electron-dense virosomes, with the accumulated vesicles

249 ctron microscopy revealed cell "ghosts" with electron-dense walls.

250 plasma membrane and the production of small electron-dense whorls.