ライフサイエンスコーパス: electroneutral

1 bOH and by a mechanism that is predominately electroneutral.

2 nic, that mediated by human SLC26A6 appeared electroneutral.

3 - 2, 2'-disulfonates and may not be strictly electroneutral.

4 (+) binding, so that the overall reaction is electroneutral.

5 rginine, which is a mutation that makes NapA electroneutral.

6 ay, thus allowing the second oxidation to be electroneutral.

7 nd complex, on the other hand, appears to be electroneutral.

8 demonstrated that this transport process is electroneutral.

9 6A6-mediated oxalate transport appears to be electroneutral.

10 odium/hydrogen exchanger, NHE1, mediates the electroneutral 1:1 exchange of Na+ and H+ across the pla

11 TP stoichiometry of the Na(+),K(+)-ATPase to electroneutral 2Na(+):2K(+):1ATP stoichiometry similar t

12 eral ClC-2 channels are required for colonic electroneutral absorption of NaCl and KCl.

13 hia coli, the UhpT transporter catalyzes the electroneutral accumulation of sugar 6-phosphate by exch

14 We conclude from these data that electroneutral, amiloride-sensitive NBC is encoded by NB

15 17 mM, transport by all three ionophores is electroneutral and apparently occurs through complexes o

16 We propose that both, electroneutral and electrogenic Na(+)/H(+) antiporters,

17 ic structure of the translocation complex in electroneutral and electrogenic Na(+)/H(+) exchangers.

18 ransports 1 Na(+), 1 K(+) and 2 Cl(-), it is electroneutral and its activation had little effect on m

19 running in the forward direction, NDCBE1 is electroneutral and mediates increases in both pH(i) and

20 atalyzes inorganic phosphate transport in an electroneutral and pH gradient-dependent manner across t

21 (+)/H(+) exchangers, electrogenic as well as electroneutral, and elegantly explains their pH regulati

22 in AE1 membrane-spanning domain convert the electroneutral anion exchanger into a Na(+) and K(+) con

23 uctive pathway has some commonality with the electroneutral anion-exchange pathway.

24 Thus, these chimeras were electroneutral, as were two others consisting of NBCe1(N

25 t is regulated through the Ca(2+)-activated, electroneutral ATP-Mg/P(i) carrier (APC).

26 enic chloride, electrogenic bicarbonate, and electroneutral bicarbonate secretion.

27 at transmembrane redox mediated by SP-AQ was electroneutral, but reaction by the other quinone-contai

28 ) antiporter NapA from being electrogenic to electroneutral by the mutation of a single lysine residu

29 The electroneutral C932R mutant of the Na(+),K(+)-ATPase ret

30 NKCC1, is a member of a small gene family of electroneutral cation-chloride cotransporters (CCCs) wit

31 sporters (KCCs) belong to the gene family of electroneutral cation-chloride cotransporters, which als

32 rted 5-HT and ions is predicted to result in electroneutral charge movement.

33 Of these, seven are known to be electroneutral chloride transporters.

34 rbonate transporter family SLC4, mediates an electroneutral chloride/bicarbonate exchange in physiolo

35 e or oxalate for chloride or bicarbonate and electroneutral chloride:bicarbonate exchange.

36 293 cells, mDRA conferred Na(+)-independent, electroneutral Cl(-)/CHO(3)(-) exchange activity.

37 ouse slc26a6 and human SLC26A6 each mediated electroneutral Cl(-)/HCO(3)(-) and Cl(-)/OH(-) exchange.

38 nism, and acute regulation, but both mediate electroneutral Cl(-)/HCO(3)(-) exchange.

39 oth of these exchangers probably mediate the electroneutral Cl--dependent HCO3-transport observed in

40 st for HCO3- transport via conductive versus electroneutral Cl-/HCO3- exchange (anion exchange, AE) p

41 - transporters while Slc26a4 functions as an electroneutral Cl-/I-/HCO(3)- exchanger.

42 found that, whereas AE1Delta(6: 7) has some electroneutral Cl-base exchange activity, the protein al

43 erefore suggest a shift from a predominantly electroneutral Cl-HCO3- exchange in normal mice, to a pr

44 red cell anion exchanger AE1 (band 3) is an electroneutral Cl-HCO3- exchanger with 12-14 transmembra

45 cument that HCO3- transport is a reversible, electroneutral, Cl dependent, Na+-independent process.

46 ments suggest that MARCKS-(151-175) forms an electroneutral complex with approximately 4 PIP(2).

47 Despite this electroneutral cotransport activity, the transporter med

48 f cellular cystine uptake via system xc-, an electroneutral cystine-glutamate exchanger.

49 human Na(+)/H(+) exchanger NHA2 (SLC9B2) is electroneutral, despite harboring the two conserved aspa

50 led pH(i) recovery rates, suggesting that an electroneutral, DNDS-sensitive, Cl(-)-HCO(3)(-) exchange

51 The exchange is probably electroneutral, energized by the transmembrane pH gradie

52 Our data are consistent with electroneutral entry of Na(+) occurring in axons and con

53 troduced as perturbations away from a nearly electroneutral equilibrium environment.

54 ta from two experimental approaches supports electroneutral exchange (one Na+ exchanged for one proto

55 The mechanism appears to involve electroneutral exchange of a TBT-dicarboxylate-H complex

56 ent cellular acidification by catalyzing the electroneutral exchange of extracellular sodium for an i

57 he cation proton antiporter family drive the electroneutral exchange of H(+) against Na(+) ions and e

58 The gastric H,K-ATPase catalyzes electroneutral exchange of H(+) for K(+) as a function o

59 In contrast to the electroneutral exchange of H+ for Na+ and neutral amino

60 YqkI mediated an electroneutral exchange, which is proposed to be a malic

61 Here we show that ASCT1 functions as an electroneutral exchanger that mediates negligible net am

62 he vesicular gastric H,K-ATPase catalyzes an electroneutral H for K exchange allowing acidification o

63 In contrast, amiloride-sensitive, electroneutral, [H(+)]-dependent NBC activity is present

64 However, in CF, carbachol resulted in an electroneutral HCO(3)(-) secretion, whereas STa induced

65 report that SLC26A4 functions as a coupled, electroneutral I(-)/Cl(-), I(-)/HCO(3)(-) and Cl(-)/HCO(

66 This attributed the DeltaV(S+) to an electroneutral increase in the effective osmotic activit

67 In contrast, expression of Slc9A (NHE3), an electroneutral ion channel, and of GlyR, an inactive Cl(

68 fficult to pursue through the application of electroneutral ionophores.

69 Under conditions that promoted electroneutral K(+)-K(+) exchange by the Na,K-ATPase, st

70 Electroneutral K+/Cl- cotransport was demonstrated in Si

71 Electroneutral K+/H+ exchange, which we propose is perfo

72 uctance, Ca 2+ -sensitive K channel, and the electroneutral K:Cl cotransporter-leading to sickle cell

73 Electroneutral lysine mutants show similar ion affinitie

74 Monensin transports Pb(2+) by an electroneutral mechanism in which the complex PbMonOH is

75 that DC5-DC10 can also be transported by an electroneutral mechanism mediated by tributyltin, a pote

76 DC6-DC10 are also transported by an electroneutral mechanism that appears to reflect transpo

77 9 and 250 microM, La3+ is transported by an electroneutral mechanism, predominately through mixed co

78 m-hydrogen exchanger (NHE-1) is a ubiquitous electroneutral membrane transporter that is activated by

79 In electroneutral membranes, the concentration of the posit

80 Electroneutral monovalent cation/proton antiport across

81 ility to mannitol at 1 hour and decreases in electroneutral Na(+) absorption, Na(+)-dependent glucose

82 ajor transport protein responsible for ileal electroneutral Na(+) absorption.

83 onsistent with a warming-induced increase in electroneutral Na(+) entry.

84 boxylic acid ionophore monensin, known as an electroneutral Na(+) ionophore, an anticoccidial agent,

85 Blocking electroneutral Na(+) movement is predicted to be useful

86 nce of bumetanide and amiloride (blockers of electroneutral Na(+) movement), the action potential amp

87 yperpolarization that is reduced by blocking electroneutral Na(+) movement.

88 Conversely, electroneutral Na(+), K(+), and Cl(-) absorption was dra

89 The slc4a10 gene encodes an electroneutral Na(+)-dependent HCO(3)(-) importer for wh

90 The electroneutral Na(+)-driven Cl-HCO3 exchanger is a key m

91 Thus, NDCBE1 encodes a human, electroneutral Na(+)-driven Cl-HCO3 exchanger.

92 Electroneutral Na(+)-H(+) exchange is present in virtual

93 Cl(-)-HCO(3)(-) exchanger (AE2) but not the electroneutral Na(+)-HCO(3)(-) cotransporter NBCn1.

94 Although it has been suggested that the electroneutral Na(+)-K(+)-Cl(-) cotransporter 1 (NKCC1)

95 ents generated by Na,K-ATPase functioning in electroneutral Na(+)-Na(+) exchange mode were measured a

96 rst electrophysiological investigation of an electroneutral Na(+)/H(+) exchanger, NhaP1 from Methanoc

97 nformational changes in MjNhaP1, an archaeal electroneutral Na(+)/H(+)-antiporter resembling the huma

98 ere, we identified two novel variants of the electroneutral Na(+)/HCO3- cotransporter NBCn1, one full

99 er vertebrates is likely responsible for the electroneutral Na(+)/lactate cotransport reported in mam

100 /L [mucosal], 0 mmol/L [serosal]) stimulated electroneutral Na+ absorption, which was inhibited by bi

101 port is distinct from epinephrine-stimulated electroneutral Na+ absorption.

102 SLC4A7 encodes the electroneutral Na+/HCO3- co-transporter NBCn1 which regu

103 , the Na+-driven Cl-/HCO3- exchanger and the electroneutral Na+/HCO3- cotransporter, have crucial rol

104 e report the cloning of three variants of an electroneutral Na+/HCO3- cotransporter, NBCn1, from rat

105 Electroneutral Na-(K)-Cl cotransporters are present in m

106 In vascular endothelium, the electroneutral Na-K-Cl cotransport system is thought to

107 We propose to rename NCBE as the second electroneutral Na/HCO(3) cotransporter, NBCn2.

108 th residues at the corresponding site of all electroneutral Na/HCO(3) transporters.

109 , and humans; approximately 73% to mammalian electroneutral Na/HCO3 cotransporters (NBCn1); 71% to mo

110 assium absorption in the rat distal colon is electroneutral, Na(+)-independent, partially chloride-de

111 NBCn1-B (which encodes 1,218 amino acids) is electroneutral, Na+-dependent and HCO3(-)-dependent, but

112 Two electroneutral, Na+-driven HCO3- transporters, the Na+-d

113 -)/HCO(3)(-) exchanger coupled with Nhe3 for electroneutral NaCl absorption across mammalian small in

114 Electroneutral NaCl absorption across small intestine co

115 electrogenic Cl(-) secretion, inhibition of electroneutral NaCl absorption and in some cases, downre

116 Electroneutral NaCl absorption mediated by Na+/H+ exchan

117 c adenosine monophosphate with inhibition of electroneutral NaCl absorption.

118 (36)Cl flux across murine jejunum, a site of electroneutral NaCl absorption.

119 NCC helps to retain potassium by increasing electroneutral NaCl reabsorption, therefore reducing Na(

120 ecently described a novel thiazide-sensitive electroneutral NaCl transport mechanism resulting from t

121 Both electrogenic and electroneutral NBC activities are saturable processes wi

122 ough it was slowed significantly, suggesting electroneutral NBC may also be operational.

123 t NBC isoforms [i.e. electrogenic (NBCe) and electroneutral (NBCn)] that exhibit tissue specific expr

124 t are controversial, with reports suggesting electroneutral (NBCn; 1HCO(3)(-) : 1Na(+); coupling coef

125 , we constructed chimeras of NBCe1-A and the electroneutral NBCn1-B, and used two-electrode voltage c

126 ominantly expressed in proximal colon, while electroneutral NBCn1C or NBCn1D (NBCn1C/D) is expressed

127 or increases in root respiration, suggesting electroneutral NH3 transport.

128 , capable of mediating both electrogenic and electroneutral (nonelectrogenic) transport processes.

129 selective for sodium (apparent Km=31 mm) and electroneutral (one sodium ion for each proton).

130 Each mutation replaced an electroneutral or electronegative residue with one that

131 n its anionic form despite its binding being electroneutral overall.

132 ast, we demonstrated that oxalate shares the electroneutral pathway mediating Na+-independent sulfate

133 ow pK(a), consequently, they cannot catalyze electroneutral proton transport in the bilayer and canno

134 Positively charged and electroneutral redox partners tend to react at the acidi

135 The results are consistent with electroneutral release of ADP before Na(+) is deoccluded

136 No electroneutral reversed uptake was detected, contradicti

137 NKCC1) is a member of a small gene family of electroneutral salt transporters that play essential rol

138 NKCC1 is a member of a small gene family of electroneutral salt transporters.

139 members of the NKCC1 gene family (slc12) of electroneutral salt transporters.

140 Short-term K(+) release is electroneutral, since electrophysiological measurements

141 fish SLC5A8 ortholog, and zSMCTn is a novel, electroneutral SMCT (zSlc5a12).

142 ium intake and plasma potassium are low, the electroneutral sodium chloride cotransporter is activate

143 With-no-lysine kinase 4 (WNK4) inhibits electroneutral sodium chloride reabsorption by attenuati

144 r and electrophysiological properties of the electroneutral sodium/bicarbonate cotransporter (NBCn1)

145 e resolved the substrate ion in the dimeric, electroneutral sodium/proton antiporter PaNhaP from Pyro

146 Transport of the electroneutral solute sorbitol via the NPPs was found to

147 nge of transport techniques to study whether electroneutral solutes use these channels or altered/sep

148 Although their transport cycle is overall electroneutral, specific partial reactions are electroge

149 electron-withdrawing, electron-donating, and electroneutral substituents enables investigation of mul

150 chiometry, which exceeds that predicted from electroneutral substrate transport.

151 nalysis established that SdcS facilitates an electroneutral symport reaction having a 2:1 cation/dica

152 ly, some of the assemblies that form are not electroneutral-that is, they possess a net charge.

153 If the BNC reduction is electroneutral, then the heme a E(m) is independent of t

154 the dianions yielded the stable and isolable electroneutral title biradicals.

155 ated Cl(-)-dependent HCO(3)(-) secretion and electroneutral transepithelial NaCl reabsorption in micr

156 Gastric H,K-ATPase is an electroneutral transmembrane pump that moves protons fro

157 a(+):2K(+):1ATP stoichiometry similar to the electroneutral transport mode of the H(+),K(+)-ATPase.

158 inding at the third site is decisive for the electroneutral transport mode of this pump.

159 f almost all cells and which mediate the 1:1 electroneutral transport of a proton and a lactate ion.

160 wo protons, performing both electrogenic and electroneutral transport of a single substrate.

161 Coupled electroneutral transport of Na+, K+ and Cl- is mediated

162 Second, it mediates coupled, electroneutral transport of proton or hydroxide with chl

163 te stoichiometry in the same membrane domain-electroneutral transport), the CF-associated aberrant HC

164 ree shows that Sp-NBC branches closer to the electroneutral type of HCO3- transporters.

165 Na(+)/ ClO(4)(-) transport stoichiometry is electroneutral, uncovering that NIS translocates differe

166 an SERTs, the transport cycle is reported as electroneutral, with a translocation of zero net charge,

167 rs such as 99mTc-sestamibi, this compound is electroneutral, with biodistribution not affected by per

168 ish (Danio rerio), electrogenic (zSMCTe) and electroneutral (zSMCTn).