ライフサイエンスコーパス: elevated plus maze

1 ty-related behavior (dark/light exploration, elevated plus maze).

2 y behavior, and anxiety (as expressed in the elevated plus-maze).

3 control animals in the open field arena and elevated plus maze.

4 LA and heightened anxiety, as measured on an elevated plus maze.

5 vioral correlates of anxiety measured in the elevated plus maze.

6 is, including the passive avoidance task and elevated plus maze.

7 was evaluated by the open field test and the elevated plus maze.

8 ntrols, but it did not alter behavior on the elevated plus maze.

9 Anxiety levels were also evaluated using an elevated plus maze.

10 ked wheel controls (LC) (20.7+/-5.7%) in the elevated plus maze.

11 creases levels of anxiety as measured by the elevated plus maze.

12 s mice moving in an open field box and in an elevated plus maze.

13 10 min prior to testing and examined in the elevated plus maze.

14 vehicle 30 or 60 min prior to testing in the elevated plus maze.

15 o reflected by an increase in anxiety in the elevated plus maze.

16 k box as well as open-arm exploration in the elevated plus maze.

17 lso tested for anxiety-like behaviors on the elevated plus maze.

18 r-exploratory (low-anxiety phenotype) in the elevated plus maze.

19 xiety-like behavior in restraint rats in the elevated plus maze.

20 havior in those animals as measured with the elevated plus maze.

21 an open field, while reducing anxiety in an elevated plus maze.

22 and produced an anxiety-like response on the elevated plus maze.

23 was withdrawn and anxiety was measured in an elevated plus maze.

24 al measures of anxiety-like responses in the elevated plus-maze.

25 proestrus female rats were examined with an elevated plus-maze.

26 hybridization 4 h after being tested on the elevated plus-maze.

27 anxiety-like behavior was accessed using an elevated plus-maze.

28 and was related to reduced fearfulness in an elevated plus-maze.

29 adigms, but contrast with those found in the elevated plus-maze.

30 task, as previously reported but not in the elevated plus-maze.

31 ease in anxiety-like behavior of rats on the elevated plus-maze 10 days after acute stress.

32 uitary-adrenocortical (HPA) responses to the elevated plus maze, a behavioral stressor known to activ

33 so reduced entries into the open arms of the elevated plus maze after water restraint.

34 e conclude that anxiety-like behavior in the Elevated Plus Maze and behavioral despair-like immobilit

35 Behavior in the elevated plus maze and behavioral suppression induced by

36 were subjected to behavioral stress using an elevated plus maze and blood was collected 15 min prior

37 Object recognition memory, anxiety on an elevated plus maze and body weight were unaffected by ph

38 anxiogenic-like behavior as assessed by the elevated plus maze and defensive withdrawal tests.

39 aviors, reduced anxiety-like behavior in the elevated plus maze and deficits in the T-maze alteration

40 mice spent more time in the open arms of an elevated plus maze and exhibited spatial working memory

41 e underlying this phenotype, focusing on the Elevated Plus Maze and Forced Swim Test as relevant beha

42 vulnerabilities for altered behavior in the Elevated Plus Maze and Forced Swim Test, respectively.

43 ic- and antidepressant-like responses in the elevated plus maze and forced swim test.

44 layed increased anxiety-like behavior in the elevated plus maze and in a light/dark box.

45 vity, increased time in the open arms of the elevated plus maze and increased immobility during the t

46 iors and reduced exploratory behavior in the elevated plus maze and light-dark box tasks.

47 l-related anxiety in rats as measured by the elevated plus maze and light/dark box exploration tests.

48 ssess genotype-dependent effects on anxiety (elevated plus maze and light/dark box), motor coordinati

49 (1A)-AR, and CAM alpha(1B)-AR animals in the elevated plus maze and light/dark box.

50 ent paradigm improved functional recovery on elevated plus maze and Morris water maze, concomitant wi

51 nd cognitive functioning were assessed using elevated plus maze and Morris water maze, respectively.

52 on also increases measures of anxiety in the elevated plus maze and neophobia to novel tastes.

53 -outs, specifically in the anxiety-provoking elevated plus maze and not in a familiar environment or

54 like behavior assessed using the open-field, elevated plus maze and novelty-suppressed feeding tests.

55 The effects of 4 weeks of wheel running on elevated plus maze and open field behavior were also inv

56 produced an anxiolytic phenotype in both the elevated plus maze and open field tests, and increased t

57 ested for anxiety-related behavior using the elevated plus maze and open field, and for endocrine res

58 vHIP decreased anxiety-like behavior on the elevated plus maze and open field.

59 rdless of sex, increased anxiety on both the elevated plus maze and open field.

60 how heightened anxiety-like behaviors in the elevated plus maze and open-field tests.

61 reduced state of anxiety as assessed in the elevated plus maze and reduced Orexin mRNA compared to a

62 behavior including central area time in the elevated plus maze and thigmotaxis in the open field tes

63 y was also unchanged as measured in both the elevated plus maze and time spent immobile in a novel en

64 ited increased anxiety-like behaviour in the elevated plus maze and were more optimistic in the cogni

65 osed rats exhibited decreased anxiety in the elevated plus-maze and a trend for decreased TH-ir in th

66 ats showed less anxiety-like behavior in the elevated plus-maze and defensive withdrawal tests than L

67 e such as decrease in open-arm entries on an elevated plus-maze and increased susceptibility to penty

68 yperlocomotion, an anxiogenic profile in the elevated plus-maze and open field tests, and reduced soc

69 rats exhibited increased locomotion in both elevated plus-maze and open field tests, suggesting heig

70 la (BLA), ERGR reduced anxiety, as tested on elevated plus-maze and open field, without affecting con

71 deficiency, we evaluated AC8 KO mice in the elevated plus-maze and open field.

72 xploratory anxiety-like behaviors, tested by elevated plus-maze and open-field tests.

73 implants increased indices of anxiety on the elevated plus-maze and produced a concomitant increase i

74 omy (OBX) altered defensive behaviors on the elevated plus-maze and the open-field differently in mal

75 educed anxiety-like behavior assessed in the elevated-plus maze and acoustic startle test, including

76 i.p.) produced anxiety-like behaviors in the elevated-plus maze and novel object exploration assays,

77 d on the propensity to avoid open arms in an elevated-plus maze and sign-trackers (ST) that are prone

78 d sucrose rewards, as well as anxiety (i.e., elevated plus maze)- and stress (i.e., forced swimming)-

79 k avoidance responding in a shuttle box, the elevated plus maze, and an air puff-induced ultrasonic v

80 , decreased time spent in the open arm of an elevated plus maze, and an odor aversion associated with

81 or the anxiolytic effects of nicotine in the elevated plus maze, and elimination of alpha4beta2-nAChR

82 vity in various tests, including open field, elevated plus maze, and light/dark transition tests.

83 id hormone corticosterone in the open-field, elevated plus maze, and social interaction tests.

84 s of anxiety - the conditioned freezing, the elevated plus maze, and the defensive-withdrawal test.

85 es of anxiety in the open field, light-dark, elevated plus-maze, and elevated zero maze tests.

86 s when mice were assessed in the open-field, elevated-plus-maze, and forced swim tests.

87 When anxiety levels were assessed in the elevated plus maze, Apoe(-/-) mice showed more anxiety t

88 Lesions had no effect on any measures in the elevated plus maze but attenuated operant suppression in

89 ike behavior in both groups, measured on the elevated plus maze, but did not affect mechanical hypers

90 ge of time dams spent in the open arms of an elevated plus-maze, but had no effect on the open-arm be

91 The increased open arm activity in the elevated plus-maze cannot therefore be secondary to incr

92 Affective (elevated plus-maze), cognitive (water-maze), and reprodu

93 ned by a decrease in open arm entries on the elevated plus maze compared to control rats and pseudopr

94 ime in and entries into the open arms of the elevated plus maze compared to handled controls, suggest

95 rol-implanted rats either not exposed to the elevated plus maze (control) or 4 h post-behavioral stre

96 alone increased anxiety-like behavior on the elevated plus maze, CUS alone or in combination with MDM

97 Knockout adults were less anxious in the elevated plus-maze, defecated less, and head-dipped more

98 le, E2, P, or E2 + P: Effects on open field, elevated plus-maze, defensive freezing, and hot-plate ta

99 or fear-reducing effects as measured on the elevated plus-maze, despite stress-induced gut microbiot

100 Performance of mice in anxiety (open field, elevated plus maze, elevated zero maze, social interacti

101 iour was assessed at weekly intervals in the elevated plus-maze, elevated T-maze, and locomotor activ

102 e, and on behavior in two anxiety paradigms, elevated plus maze (EPM) and fear conditioning.

103 from these populations were subjected to the elevated plus maze (EPM) and novel environment to assess

104 of two-trial light- dark (LD) and two-trial elevated plus maze (EPM) tests arranged in counterbalanc

105 In the elevated plus maze (EPM), AgNS-exposed rats showed great

106 loring standard and modified versions of the elevated plus maze (EPM), an innate anxiety paradigm.

107 in a battery of tests--novel field activity, elevated plus maze (EPM), and social interaction (SI) at

108 In the elevated plus maze (EPM), restraint decreased the number

109 l freezing, and an anxiety-like trait in the elevated plus maze (EPM).

110 xiety-type behaviors were measured using the elevated plus maze (EPM).

111 Utilizing the elevated plus-maze (EPM) after exposure to escapable sho

112 Prior undrugged exposure to the elevated plus-maze (EPM) alters future behavioral strate

113 n increased exploratory behavior in both the Elevated Plus-maze (EPM) and the Black and White (B-W) t

114 assessed using a dry land maze (DLM) and an elevated plus-maze (EPM) at 4-month intervals.

115 The EZM paradigm has advantages over the elevated plus-maze (EPM) paradigm with respect to measur

116 ry of MS15 would display less anxiety in the elevated plus maze (EPMZ) and novelty-suppressed feeding

117 mUcn treated rats tested in the elevated plus maze following the delayed pretreatment in

118 ng memory, a water maze task for escape, the elevated plus maze for anxiolytic/anxiogenic effects, pl

119 .e., sucrose preference) and aversive (i.e., elevated plus-maze, FST) circumstances was then assessed

120 ing multiple stressors including open-field, elevated plus maze, holeboard, light-dark box and novel

121 hile enhancing anxiety-like responses in the elevated plus maze in adulthood.

122 ly increased anxiety-related behavior in the elevated plus maze in both acutely and repeatedly restra

123 me spent on and entries into open arms of an elevated plus maze in both saline- and cocaine-treated g

124 sessed anxiety-like behavior by means of the elevated plus maze in control adult rats and in adult ra

125 lic indices, and exploratory behavior on the elevated plus maze in male C57BL/6J mice.

126 es to unconditioned nociceptive stimuli, and elevated plus maze in Sprague Dawley male rats, and in t

127 decreased rats' open-arm exploration in the elevated plus-maze in both male and female rats.

128 rances and time spent in the open arm of the elevated plus-maze in both sexes and ages.

129 pups (sensitization) but reduced fear in the elevated plus-maze in both sexes.

130 and spent less time in the open arms of the elevated plus maze, indicating high levels of innate fea

131 The avoidance test and elevated plus maze induced prominent Fos-LI in select br

132 (KO) mice were tested in locomotor monitors, elevated plus maze, inhibitory avoidance, acoustic start

133 The elevated plus maze is a widely used behavioral assay for

134 suppressed and anxiety-like behavior in the elevated plus maze is dampened.

135 ustic startle response, prepulse inhibition, elevated plus-maze, light <--> dark exploration, Morris

136 o showed markedly reduced levels of anxiety (elevated plus maze, marble burying, novelty suppressed f

137 wing oral administration in mice in both the elevated plus maze model of anxiety (ED50 = 0.5 mg/kg) a

138 In standard behavioral tests (open field and elevated plus maze), mRGC activation induced behaviors c

139 In the elevated plus maze, mUcn 3 injections significantly incr

140 ing the following tests: Light Dark Latency, Elevated Plus Maze, Novel Object Recognition, and Barnes

141 ed by increased anxiety-like behavior on the elevated plus maze on GD18.

142 t females displayed decreased anxiety on the elevated plus maze on GD9 compared to NP females, follow

143 e exhibited an anxiety-like phenotype in the elevated plus maze, open field, and light/dark box tests

144 ry wheel running on behavior measures in the elevated plus maze, open field, social interaction and c

145 R mice showed lower levels of anxiety in the elevated plus maze, opposing the known high anxiety in c

146 unconditioned anxiety-like responses in the elevated plus maze or basal acoustic startle amplitude.

147 exposed to single-trial fear conditioning or elevated plus maze or sacrificed for basal diurnal corti

148 s have no effect on open-arm behavior in the elevated plus-maze or changes in startle reactivity indu

149 en field activity, open arm avoidance on the elevated plus-maze or conditioned place preference for c

150 no changes in anxiogenic behavior using the elevated plus maze (p>0.05).

151 spatial and nonspatial learning and memory, elevated plus maze performance, electrophysiological mea

152 Behavior analyses by open field test, elevated plus maze, Reciprocal Social Interaction, and a

153 , and decreased time in the open arms of the elevated plus maze relative to control mice.

154 In the elevated plus maze, SERT-/- mice demonstrated anxiety-li

155 ng successive alleys (a modified form of the elevated plus-maze), social interaction, and hyponeophag

156 osing effects on exploratory behavior in the elevated plus-maze, somatic mechanical threshold, and th

157 eir behavior, we assessed the open field and elevated plus maze spatiotemporal patterning of activity

158 In the present study, we used elevated plus-maze, startle and prepulse inhibition, ope

159 ar to those found at 8 weeks, but not in the elevated plus maze suggesting a temporal effect of wheel

160 xhibit reduced anxiety-like behaviors in the elevated plus maze task and deficits in cued and context

161 In the elevated plus maze task, we found that HT mice after sei

162 scrimination were assessed in an appetitive, elevated plus-maze task in 4 groups of mice: knockout mi

163 the cued fear-conditioning, open field, and elevated plus maze tasks.

164 igher anxiety response in the open-field and elevated plus-maze tasks.

165 eatment induced anxiety-like behavior in the elevated plus maze test and elevated intracranial self-s

166 ice showed less anxious-like behavior on the elevated plus maze test and had higher spontaneous recov

167 anxiety-like behavior and exploration in the elevated plus maze test and sexual behavior.

168 -type mice in the open field test and in the elevated plus maze test of anxiety.

169 In the elevated plus maze test, administration of anti-SVG-30 e

170 linical rodent models of anxiety, namely the elevated plus maze test, open field test, and food neoph

171 thdrawal (situational anxiety) model and the elevated plus maze test.

172 exploration or anxiety-like behavior in the elevated plus maze test.

173 thdrawal (situational anxiety) model and the elevated plus maze test.

174 Locomotor activity and elevated plus maze test/forced swim test were conducted

175 etween trait anxiety levels evaluated by the elevated plus-maze test and CeA/LA activity.

176 s with or without BDNF coinfusion, using the elevated plus-maze test and two-bottle free-choice parad

177 s disease transgenic mice were tested in the elevated plus-maze test of anxiety at 6, 8, 10 and 12 we

178 In the elevated plus-maze test, no significant effects were det

179 activity and differences from control in the elevated plus-maze test.

180 n) and GR(wt/Qn) mice were confirmed by the "elevated plus maze" test in which GR(Qn/Qn) and GR(wt/Qn

181 r did transgenicity affect anxiety levels in elevated plus-maze testing.

182 d swimming tests), anxiety (black and white, elevated plus maze tests), aggressiveness (resident-intr

183 In both open field and elevated plus maze tests, socially isolated mice showed

184 ion, sucrose preference, tail suspension, or elevated plus maze tests.

185 vaccination altered mouse behavior in T- and elevated plus-maze tests and simvastatin counteracted su

186 not alter behavior in the open field and the elevated plus-maze tests suggesting not only that the mo

187 -related indices in the novel open field and elevated plus-maze tests.

188 g PS rats were more motile in open field and elevated plus maze than control rats, and they learned f

189 ts to spend more time in the open arms of an elevated-plus maze than controls, indicating that inhibi

190 ice had a smaller heart rate increase in the elevated-plus maze than did wild-type littermates.

191 differences of anxiety-like behavior in the elevated plus maze that were correlated with BLA neurona

192 sed measures of anxiety-like behavior in the elevated plus maze, the light/dark box, and the open fie

193 une NZW control mice on 3 anxiety tasks: the elevated plus maze, the open-field drink test, and the n

194 -like reactivity was then measured using the elevated plus-maze, the defensive withdrawal test and ac

195 No changes were recorded in the elevated plus-maze, the light-dark transition, and defen

196 On Trial 1 in the elevated plus-maze, the receptor antagonists were withou

197 In addition, all rats were tested on an elevated plus maze to assess anxiety-like behavior and i

198 alongside a traditional measure of anxiety (elevated plus maze), to investigate the effects of juven

199 Examination of performance on the elevated plus maze under conditions designed to minimize

200 fear conditioning, yet baseline fear on the elevated plus maze was intact.

201 ield activity nor baseline exploration of an elevated plus-maze was affected by MTIP (1-10 mg/kg).

202 ortion of time spent on the open arms of the elevated plus-maze was found after 2.5 and 5 micrograms

203 , social defeat stress, forced swimming, and elevated plus maze) was assessed.

204 possibility, anxiety-related behaviors in an elevated plus maze were assessed in postpartum rats afte

205 Measures of anxiety-related behaviors in the elevated plus-maze were significantly (p < 0.05) decreas

206 s (tested in open field, marble burying, and elevated plus maze) were higher, which were alleviated b

207 6 of injections, subjects were tested on the elevated plus maze which provides a measure of anxiety,