ライフサイエンスコーパス: eliminate the need for

1 In addition, at-column heating is used to eliminate the need for a convection oven and to greatly

2 as the color moieties, our approach can even eliminate the need for a fluorescent microscope, allowin

3 convective mixing at low Reynolds number to eliminate the need for a physical membrane to separate t

4 The use of the IPAD technique eliminated the need for a second derivatization step to

5 This eliminated the need for a separate negative control, eff

6 cular tissue assembly and, importantly, also eliminates the need for a bioreactor-based scaffold cell

7 pass using a single photomultiplier tube and eliminates the need for a polarizer on the emission path

8 Thus, the use of RuNPs/GC eliminates the need for a preconcentration step in strip

9 Since the ensuing SET-based cyclization eliminates the need for a prefunctionalized aryl ring, t

10 hanism is nonreactive, operates in situ, and eliminates the need for a prepolarizing magnet, its comb

11 This eliminates the need for a separate AED specifically for

12 ksRepo eliminates the need for a single microarray platform as

13 f-reporting 15-min hybridization step, which eliminates the need for a wash step.

14 s direct electrical coupling with C15/16/17, eliminating the need for a cerebral CPG.

15 Continuous sample introduction is used, eliminating the need for a sample injection mechanism.

16 acket into the ion cyclotron resonance cell, eliminating the need for a separate accumulation and ion

17 requency of shorter ones of various lengths, eliminating the need for a separate set of reference dat

18 of modern contraception can reduce but never eliminate the need for abortion.

19 This eliminates the need for acceptor photobleaching to deter

20 The method eliminates the need for acid protection and produces a w

21 The method eliminates the need for acid protection and produces N-a

22 the analysis on routinely taken cephalograms eliminates the need for additional exposure to X-ray rad

23 This formulation eliminates the need for additional functional monomers a

24 the fellow eye when using a monocular trial eliminates the need for additional office visits to conf

25 tly from linear DNA templates within 90 min, eliminating the need for additional cloning steps, which

26 ded with complete acceptor regioselectivity, eliminating the need for additional protecting group man

27 y reducing the amount of sample required and eliminating the need for additional sample handling.

28 electrolyte (BGE) instead of the sample-thus eliminating the need for additional sample manipulation,

29 illary at predetermined time intervals, thus eliminating the need for additional sample-handling step

30 Furthermore, it eliminates the need for adjuvant treatment in low-risk p

31 cost-efficient, and on-site detection, while eliminating the need for advanced expensive instrumentat

32 g lithographically patterned substrates that eliminates the need for alignment and, thus, is scalable

33 fetuses with Down's syndrome, and reduce or eliminate the need for amniocentesis.

34 d secondly by testing whether we are able to eliminate the need for an explicit choice of features al

35 rating pressure was less than 200 kPa, which eliminated the need for an expensive high-pressure pump

36 introducing a charged residue at this region eliminates the need for an activating phosphorylation.

37 lectric polymer layer into the device, which eliminates the need for an external bias.

38 oncentration-dependent response to IgG, thus eliminating the need for an enzyme-substrate system.

39 /min eluate stream to the mass spectrometer, eliminating the need for an external pump in the system.

40 ermined by its UV absorption at 280 nm, thus eliminating the need for an internal standard.

41 l disease, improved imaging techniques could eliminate the needs for analysis of randomly selected bi

42 Moreover, this high specificity eliminates the need for analysis of the lipid product by

43 artifacts from fluorescence interference and eliminates the need for antibody specificity to methylat

44 can directly costimulate gammadelta T cells, eliminates the need for any accessory cells.

45 e functionalized for a specific target, thus eliminating the need for any chemotherapeutic agents.

46 as central to obtaining high sensitivity and eliminating the need for any detection equipment.

47 digest was injected directly into the chip, eliminating the need for any sample-handling steps after

48 imal saphenous vein bypass graft anastomoses eliminates the need for aortic clamping during coronary

49 es the constant in the asymptotic bound, and eliminates the need for approximate frames.

50 cision by comparative genomic hybridization, eliminating the need for array replicates and complex st

51 ation and subsequent fragmentation, we could eliminate the need for authentic standards for identific

52 Sentinel lymph node dissection (SLND) has eliminated the need for axillary dissection (ALND) in pa

53 Furthermore, the method is simplified, eliminating the need for bias modulation lock-in detecti

54 ens that result in denim blue colonies, thus eliminating the need for biochemical analysis and antimi

55 e method may also speed genome sequencing by eliminating the need for biological cloning.

56 This procedure eliminates the need for blocking steps, due to a decreas

57 There have been suggestions to eliminate the need for BM examinations when defining com

58 Utilizing an all-electronic approach eliminates the need for bulky optical components and cam

59 be catalytically active towards PS, thereby eliminating the need for carbon matrix and their process

60 natural contrast in fully hydrated cells and eliminates the need for chemical fixatives or contrast e

61 the underlying PML-RARalpha oncoprotein has eliminated the need for chemotherapy for disease cure.

62 ses the efficacy of CpG vaccination, thereby eliminating the need for chemotherapy.

63 c agent to eliminate pituitary gonadotrophs, eliminating the need for chronic GnRH analogue administr

64 eating an antireflux barrier and reducing or eliminating the need for chronic medical therapy or fund

65 This eliminates the need for cloning of tRNA genes, large-sca

66 viruses was assessed directly by the assay, eliminating the need for cloning, expressing, and purify

67 bservation of individual haplotypes, thereby eliminating the need for collecting and genotyping DNA f

68 ertapenem may be a useful option that could eliminate the need for combination and/or multidosed ant

69 r for the transit of dietary fat and thereby eliminate the need for complete diet and fecal collectio

70 ce (PRS) used for the MP experiment, we have eliminated the need for complex weighting matrices.

71 ctive technique of inducing cold sensitivity eliminates the need for complex mutations and provides a

72 le therapies while substantially reducing or eliminating the need for complex formulations.

73 This simple fabrication procedure eliminates the need for complicated wiring of the indepe

74 which the PEDOT backbone is conductive, thus eliminating the need for conducting additives.

75 des are already observed at the MS/MS level, eliminating the need for conducting MS(3) or sequential

76 The assay demonstrated the potential to eliminate the need for confirmatory testing in almost al

77 rritories [7] or dominance status [1, 5] can eliminate the need for confrontation and the associated

78 oids the use of aqueous basic solutions, and eliminates the need for continuous stirring during oxida

79 activity and has a substantial postural role eliminating the need for continuous muscle activity and

80 nd dense packaging of building blocks, which eliminates the need for conventional Watson-Crick base p

81 grates these components on a single LC chip, eliminating the need for conventional LC connections.

82 of L. sylvatica is sufficiently buffered to eliminate the need for correction of H(+) concentration

83 on of genomic DNA fragments of interest that eliminates the need for costly and time consuming synthe

84 The technique eliminates the need for costly or specialized microelect

85 ead issues and is seamlessly generated, thus eliminating the need for costly two-step processing.

86 minimal number of primary transformants and eliminates the need for crossing, while the use of fluor

87 ins that are difficult to crystallize, while eliminating the need for crystal harvesting and cryo-coo

88 ed functional handles and diversity elements eliminates the need for difficult downstream functionali

89 directly from cells is highly reproducible, eliminates the need for DNA template purification, and a

90 r surface of the inner membrane of DsbB that eliminated the need for DsbA.

91 pears to have decreased even further or even eliminated the need for early permanent pacing.

92 Because a single-point mutation could eliminate the need for editing at the Q/R site and Q/R-u

93 rs the development of SIMS in bioanalysis by eliminating the need for either heteroatom or isotope la

94 Herein, we eliminated the need for electrode conditioning by loadin

95 l gradient forces and backscattering forces, eliminating the need for electronic feedback.

96 sitioning the droplets in the electric field eliminated the need for electroosmotic flow (EOF) or hyd

97 This approach eliminates the need for empirical parameters and provide

98 immunogenic epitopes and marks a step toward eliminating the need for empirical epitope testing for v

99 This method eliminates the need for enriched uranium and the radioac

100 oma appears to be safe and effective and may eliminate the need for enucleation in many patients.

101 photovoltaic copolymers, this DARP protocol eliminates the need for environmentally harmful, toxic o

102 AgNPs eliminate the need for enzymatic amplification, thereby

103 This system eliminates the need for enzymatic assembly and reduces a

104 Overall, the analytical platform eliminates the need for enzymatic reactions, heat denatu

105 intrinsic biomolecular signatures, therefore eliminating the need for exogenous fluorescent labeling.

106 at from inducible or constitutive promoters, eliminated the need for expensive inducers, reduced acet

107 This digital mask eliminates the need for expensive and time-consuming chr

108 This method eliminates the need for expensive marker development in

109 of alkenyl-oxocarbenium intermediates, which eliminates the need for expensive transition metal Lewis

110 decreased background autofluorescence while eliminating the need for expensive optical hardware, sup

111 vasive imaging method is needed to reduce or eliminate the need for extended pelvic LN dissections (e

112 t 1) allows for easier solution preparation, eliminating the need for extended heating or sonicating;

113 ndards and a secondary reference standard to eliminate the need for external standard calibration and

114 ticles for microfluidic device applications, eliminating the need for external forces or sheath flows

115 sorb via hydrolysis and/or metabolic action, eliminating the need for extraction.

116 or in combination with tomosynthesis and may eliminate the need for FFDM as part of a routine clinica

117 scale tunable laser sources (e.g. VCSEL) and eliminates the need for fiber amplifiers and highly prec

118 rent collector via short conducting linkages eliminates the need for fillers, resulting in a material

119 a unique and reversed loading procedure that eliminates the need for fine pressure control or externa

120 cells using small amounts of detergent, thus eliminating the need for fixation, and fluorescence sign

121 are diagnostics in resource poor settings by eliminating the need for fluorescent labeling and optica

122 e use of other surgical adjuncts to delay or eliminate the need for fractionated radiotherapy.

123 rtment patient population, TRO CT can safely eliminate the need for further diagnostic testing in ove

124 G and a normal endometrial biopsy result may eliminate the need for further studies.

125 esorption, and spectroscopic detection steps eliminates the need for gas chromatographic separation p

126 The assay uses real-time detection, eliminating the need for gel electrophoresis.

127 gy can be adapted to any genetic background, eliminating the need for generations of backcrossing to

128 ardiac chamber volumes, which is achieved by eliminating the need for geometric modeling and the erro

129 ant goal in enantioselective synthesis as it eliminates the need for having available the two enantio

130 sted ionization (MAI)-mass spectrometry (MS) eliminates the need for high voltage, a heat source, las

131 lained with a core-averaged field of 2.5 mT, eliminating the need for high fluid viscosity or a stron

132 ed nose-only exposure was well-tolerated and eliminated the need for housing animals outside the viva

133 This approach eliminates the need for hybrid methods and enables syste

134 simplifies the generation of antibodies and eliminates the need for hybridomas.

135 d how tethering IL2 to its receptor IL2Rbeta eliminates the need for IL2Ralpha and IL2Rbeta, offering

136 Ideally, they are also autologous to eliminate the need for immune suppression, which can hav

137 ect that our antibody design approach--which eliminates the need for immunization or screening to ide

138 Encapsulation of cells has the potential to eliminate the need for immunosuppression for cellular tr

139 To eliminate the need for indefinite treatment, there is gr

140 uilibrium (LD) at recently selected alleles, eliminating the need for inferring haplotype.

141 (IRESs) to minimize or, like the CrPV IRES, eliminate the need for initiation factors.

142 first ever colourant-transposing pixel that eliminates the need for ink microencapsulation or pixel

143 Such changes facilitate access and eliminate the need for installation of CD-ROMs and the a

144 This eliminates the need for insulators to be subjected to a

145 d, suggesting that the more open active site eliminates the need for intermediate binding sites for t

146 The S-ICD offers the advantage of eliminating the need for intravenous and intracardiac le

147 notyped volunteers and developed a method to eliminate the need for invasive arterial blood sampling.

148 fied may help to assess hepatic fibrosis and eliminate the need for invasive liver biopsies.

149 alization of sentinel lymph node metastases, eliminating the need for invasive lymphadenectomy.

150 form to accurately assess lymph node status, eliminating the need for invasive nodal dissections that

151 g L(-1)) below common discharge limits, thus eliminating the need for iron sludge removal, which is o

152 y resembles biological membrane bilayers and eliminates the need for isotopic labeling.

153 the EC-array signal using Faraday's law can eliminate the need for isotopically labeled internal sta

154 hout raising any concern for safety, and can eliminate the need for keratoplasty.

155 ng (CXL) is a treatment for keratoconus that eliminates the need for keratoplasty in most patients.

156 isolated by ultracentrifugation, effectively eliminating the need for laborious antigen purification

157 dissected tissue stains-but time is saved by eliminating the need for larval dissections and by allow

158 ration of these functions into a single tool eliminates the need for lengthy data handling and parsin

159 with gene predictions as a parent database, eliminating the need for libraries of known genes.

160 om prolonged implantation and to potentially eliminate the need for lifelong anticoagulation.

161 directly in novel, functional ligands, thus eliminating the need for ligand exchange, and (2) polyme

162 The approach eliminates the need for linear polymeric precursors and

163 term cryopreservation method that completely eliminates the need for LN2.

164 The induction of transplant tolerance would eliminate the need for long-term immunosuppression, real

165 The mmTIRF system eliminates the need for machining custom parts by the en

166 patients could undergo targeted procedures, eliminating the need for major surgery, while others cou

167 fast and adaptable to large-scale data sets, eliminating the need for manual integration in ~80% of t

168 ccommodate arbitrary family structures, thus eliminating the need for many different ad hoc tests.

169 Our inducible cyanobacterial lysing system eliminates the need for mechanical or chemical cell brea

170 l force fields), continuous filtration, thus eliminating the need for membrane replacement.

171 ity of pharmacodynamic target attainment and eliminates the need for microbiology labs to perform con

172 n of inheritance patterns in intact tetrads, eliminating the need for microdissection and permitting

173 This eliminates the need for microfluidic channels, provides

174 This approach eliminates the need for missed event correction.

175 ternative to single-compound libraries while eliminating the need for molecular target validation.

176 ficiency of chiral selector determination by eliminating the need for multilibrary syntheses, as oppo

177 droxide ions of CH for long periods of time, eliminating the need for multiple visits for apexificati

178 olution and with spectra of much higher SNR, eliminating the need for multivariate methods to identif

179 wever, immobilizing CYPs on an electrode can eliminate the need for NADPH and CPR provided the enzyme

180 st, constitutively enhanced membrane binding eliminates the need for NC to produce a WT level of FRET

181 Eliminating the need for nephrotoxic immunosuppressive d

182 eir own nitrogen requirement, so reducing or eliminating the need for nitrogen fertilizer; enhancing

183 th cell protein is a significant step toward eliminating the need for noncellular protein sequences i

184 restore normal gastrointestinal function and eliminate the need for nutritional supplementation or tr

185 Incorporation of a resonant coil eliminates the need for onboard power and external conne

186 ations that accumulate during carcinogenesis eliminate the need for one or the other of them.

187 Performing DALK on DSAEK eliminates the need for open-sky surgery, achieving visu

188 g performed in the intensive care unit, thus eliminating the need for operating room facilities and p

189 namic susceptibility contrast MR imaging and eliminate the need for operator input and lengthy postpr

190 lopment of new drugs that may cure patients, eliminating the need for organ transplants altogether.

191 ital resources and can lower costs by either eliminating the need for other, more expensive tests or

192 educe nonuniformity of excitation to 5%, and eliminate the need for outer volume suppression.

193 The software uses contemporary methods that eliminate the need for patient-specific material propert

194 A positive SRS does not eliminate the need for performing (18)F-FDG PET, which i

195 ward minimizing operator radiation exposure, eliminating the need for personal protective apparel, an

196 conventional nonlinear media, the zero index eliminates the need for phase matching, allowing efficie

197 Finger-prick diagnostics eliminated the need for phlebotomy.

198 contained within a single genetic construct, eliminating the need for plasmid shuttling and allowing

199 nt scheme that makes minimal assumptions and eliminates the need for possibly biased human assessment

200 making either error (i.e. Type I or II) and eliminates the need for post-hoc adjustments.

201 within minutes after the completion of PCR, eliminating the need for post-PCR sample manipulation.

202 and peptides were readily recovered from gel eliminating the need for postdigestion extraction.

203 Marking eliminates the need for postprocedural needle localizati

204 "on the fly" by the central diffraction beam eliminating the need for precise phase plate alignment.

205 easured TNT in seawater by direct injection, eliminating the need for preconcentration or pretreatmen

206 mplemented a standard addition method, which eliminated the need for predetermined calibration curves

207 , which is performed at ambient temperature, eliminates the need for preheated buffers or additional

208 ial new way to deliver meal-related insulin, eliminating the need for preprandial injections.

209 We show how to eliminate the need for prior parameter specification by

210 Since CE-SSCP eliminates the need for probes to have different lengths

211 recipients with CMV-seropositive donors and eliminates the need for prolonged IV access.

212 ce how we manage our patients in the future, eliminating the need for prolonged hospital stay after s

213 sections are heated in citrate buffer, which eliminates the need for protease treatment, thus preserv

214 e with both electrodes in a Li-O(2) cell may eliminate the need for protecting the anode with a ceram

215 he absolute number concentration of proteins eliminating the need for protein-specific calibration.

216 ity and versatility of conventional tags but eliminate the need for proteolytic tag removal.

217 The Chip EIA platform has eliminated the need for pumps and valves through utilizi

218 ique antibiotic resistance markers, and this eliminates the need for purification of fragments after

219 LIC eliminates the need for purification of fragments before

220 Attempts are now made to use PET scans to eliminate the need for radiation therapy in some patient

221 superior results with higher throughput and eliminate the need for radioactive waste disposal; hence

222 superior results with higher throughput and eliminated the need for radioactive waste disposal.

223 orescence (CE-LIF) can reduce protocol time, eliminate the need for radioactivity, and provide superi

224 relations encoding gene/protein interactions eliminate the need for random selection of components in

225 within 100 mum from the endothelial surface eliminates the need for reaching the central cornea for

226 The use of a methanol-based buffer eliminates the need for reagents that interfere with chr

227 The positive nature of the ion eliminates the need for real-time instrument polarity sw

228 ecific knockdown of roX1 and roX2 RNAs, thus eliminating the need for recruiting chromatin modifying

229 t) at near the engine exhaust temperature to eliminate the need for reductant refilling and extra hea

230 ts required for film buildup without excess, eliminating the need for repetitive rinsing steps.

231 ge and reproducible SERS enhancements, which eliminates the need for resonant wavelength matching of

232 MAGIC eliminates the need for restriction enzymes, DNA ligases

233 d stabilizes endogenous FVIII : C, which may eliminate the need for rFVIII after the first infusion.

234 In the first half of 2014, the ACA did not eliminate the need for RWHAP safety net provider visit c

235 aser-desorption ionization time-of-flight MS eliminate the need for sample processing and make this t

236 iological matrixes and therefore potentially eliminating the need for sample cleanup and chromatograp

237 zes the probe value through the probe model, eliminating the need for sample normalization.

238 s 25(OH)D3 from its binding protein in situ, eliminating the need for sample preparation.

239 identifying peripheral biomarkers that will eliminate the need for scalp biopsies.

240 In particular, some of these techniques eliminate the need for scanning of one of the gratings (

241 ower pKa of Sec in comparison to that of Cys eliminates the need for Sec to be protonated.

242 ame chemical information as tissue sections, eliminating the need for sectioning before MS analysis.

243 rate of expressing plants is close to 100%, eliminating the need for selectable markers.

244 A and antigens early after RNA transfection, eliminating the need for selection of replication-positi

245 DAPA eliminates the need for separate protein expression, pur

246 This eliminates the need for serial dilutions in a separate t

247 valuation of CLA(+) T cells in the blood may eliminate the need for skin biopsies.

248 ow-cost permanent storage of digital images, eliminating the need for slow, bulky and expensive mecha

249 emperatures exceeding 300 degrees C, thereby eliminating the need for solar concentrators for mid-tem

250 gle-stranded DNA for pyrosequencing, thereby eliminating the need for solid-phase sample preparation

251 improved the quality of life of patients by eliminating the need for some surgical procedures.

252 Our method eliminates the need for sophisticated instruments and hi

253 that was adducted can be established, which eliminates the need for specific parametrization of prot

254 suppressing the interfering matrix signals, eliminating the need for specimen pretreatment other tha

255 that coelute from the column ensemble, thus eliminating the need for spectral deconvolution of those

256 cteria with low recombineering efficiencies, eliminating the need for ssDNA recombineering optimizati

257 a gel by excitation with long UV light, thus eliminating the need for staining with ethidium bromide.

258 This technique eliminates the need for sub-tiles which perform binary a

259 This new model eliminates the need for subjective variables such as asc

260 dentical treatment of sample and calibrators eliminates the need for subtracting the procedural blank

261 e tissue transplants because tolerance would eliminate the need for such immunosuppression.

262 ll-suited for field instrumentation since it eliminates the need for support gases, permits smaller,

263 A MES/TRIS buffer system at pH 6.1 eliminates the need for surface preconditioning procedur

264 use of almost any molecule as a reporter by eliminating the need for surface attachment.

265 essful, percutaneous transhepatic venoplasty eliminates the need for surgical revision, portacaval sh

266 rm for noninvasive assessment of ALN status, eliminating the need for surgical examination of patient

267 ophobic network or enhance hinge flexibility eliminate the need for the conserved salt bridge at the

268 ncept of His-tagged adaptor molecules, which eliminate the need for the target protein or complex to

269 This eliminated the need for the deoxygenation step that is e

270 On the one hand, our approach eliminates the need for the acquisition of dynamic CT.

271 PDMS is superior to the glass substrate and eliminates the need for the blocking step which is requi

272 The use of LAMP eliminates the need for the cycling of temperatures and

273 to the embedded topography from above, CLINT eliminates the need for the high pressures or electric f

274 However, a "strong" TATA box ("TATAAA") eliminates the need for the PU.1 binding site and for PU

275 The epitope-tagged transgenic line eliminates the need for the self-reporting GFP activity

276 all TM and periplasmic domains tested, thus eliminating the need for the cumbersome spheroplast-prot

277 randomly distributed transposon insertions, eliminating the need for the selection of a population c

278 ctural and functional investigation, thereby eliminating the need for the unstable and radio-hazardou

279 ntravenous delivery of volatile anesthetics, eliminating the need for the use of large and costly vap

280 is a feasible detection method for dsDNA and eliminates the need for thermal denaturing steps typical

281 pirical validation of reflection-based FTIRM eliminates the need for thin sections of bone and more r

282 Tailoring of graft composition eliminates the need for time-consuming blocking steps, s

283 h intrastrain polymorphism rate in zebrafish eliminates the need for time-consuming map crosses.

284 of tumors in unsectioned tissue layers, thus eliminating the need for tissue sectioning.

285 olubility and stability in aqueous media and eliminates the need for toxic co-solvents or pH adjustme

286 Compared to quantative PCR, ddPCR eliminates the needs for traditional standards; instead,

287 This mobile-reader could eliminate the need for trained diagnosticians to perform

288 It eliminates the need for training data to establish error

289 ve demonstrated that lenalidomide reduces or eliminates the need for transfusions in some patients wi

290 rimarily at the micro-structural level: this eliminates the need for two separate mechanisms in descr

291 e used as a screening method for malrotation eliminating the need for unnecessary barium studies.

292 VisionGraft Sterile Cornea eliminates the need for use of fresh donor corneal tissu

293 fy T cells to reduce the cell number needed, eliminate the need for vaccines or systemic IL-2, and im

294 l estimations of the QRRK parameters, and it eliminates the need for variational transition state the

295 To eliminate the need for venous access, we designed and te

296 loride patient-controlled transdermal system eliminates the need for venous access and complicated pr

297 It eliminates the need for vessel-dependent adjustment of t

298 PDMS substrates eliminate the need for vibration isolation and allow dir

299 Depletion of CAML in human cells eliminated the need for Vpu in enhancing HIV-1 and murin

300 atial resolution in imaging applications and eliminating the need for washout of mislocalized sensor.