ライフサイエンスコーパス: elongation factor G

1 by RRF (ribosome recycling factor) and EF-G (elongation factor G).

2 compensated by mutations in the translation elongation factor G.

3 mbled by ribosome recycling factor (RRF) and elongation factor G.

4 This implies that elongation factor G actively pushes both the decoding si

5 ent translational GTPase factors, along with elongation factor G and BPI-inducible protein A.

6 on change in Efl1 equivalent to changes that elongation factor G and eEF2 undergo during translocatio

7 he two release factors is as good as between elongation factor G and elongation factor Tu-guanosine-5

8 Subsequent binding of elongation factor G and GTP hydrolysis results in a cloc

9 osomes at a site that coincides with that of elongation factor G and has a GTPase activity that is se

10 The translation factors, elongation factor G and ribosome recycling factor, are k

11 st our method on the experimental cryo-EM of elongation factor G and show that the model obtained is

12 ational GTPase (trGTPase) factors along with elongation factors G and 4 (EF-G and EF4).

13 ver, the antibiotic has negligible effect on elongation factor G catalyzed translocation of tRNA and

14 Elongation factor-G-catalyzed translocation of mRNA and

15 e single-dimer ribosomal particles supported elongation factor G dependent GTP hydrolysis and protein

16 scribe a new sensitive method for monitoring elongation factor G-dependent translocation of the mRNA

17 of this base-pair in peptide bond formation, elongation factor G-dependent translocation, and peptide

18 inked ribosomes were specifically blocked in elongation factor G-dependent translocation.

19 iostrepton, which inhibits the activities of elongation factor G (EF-G) and EF-Tu by binding to the r

20 Ribosome recycling factor (RRF), elongation factor G (EF-G) and GTP split 70S ribosomes i

21 enger RNA (mRNA), in a reaction catalyzed by elongation factor G (EF-G) and guanosine triphosphate (G

22 The antibiotic fusidic acid (FA) targets elongation factor G (EF-G) and inhibits ribosomal peptid

23 Elongation factor G (EF-G) and ribosome recycling factor

24 ion (ALC) is formed between the G' domain of elongation factor G (EF-G) and the L7/L12-stalk base of

25 During protein synthesis, elongation factor G (EF-G) binds to the ribosome and pro

26 After peptide-bond formation, elongation factor G (EF-G) binds to the ribosome, trigge

27 nt crystal structures of G proteins, such as elongation factor G (EF-G) bound to the ribosome, as wel

28 bits bacterial protein synthesis by blocking elongation factor G (EF-G) catalyzed translocation of me

29 The guanosine triphosphatase (GTPase) elongation factor G (EF-G) catalyzes the subsequent move

30 The universally conserved GTPase elongation factor G (EF-G) catalyzes the translocation o

31 ibosome recycling factor (RRF) together with elongation factor G (EF-G) disassembles the post- termin

32 complex through the ribosome is promoted by elongation factor G (EF-G) during the translation cycle.

33 ction of ribosome recycling factor (RRF) and elongation factor G (EF-G) in a guanosine 5'-triphosphat

34 ersally conserved ribosome-dependent GTPase [elongation factor G (EF-G) in prokaryotes and elongation

35 coding region, resulting from the binding of elongation factor G (EF-G) in various forms.

36 Initiation factor 2 (IF2) and elongation factor G (EF-G) induce similar changes in rib

37 Elongation factor G (EF-G) is a guanosine triphosphatase

38 Elongation factor G (EF-G) is a universally conserved tr

39 Binding of elongation factor G (EF-G) shifts this equilibrium towar

40 the ribosomal translocation, the binding of elongation factor G (EF-G) to the pretranslocational rib

41 Elongation factor G (EF-G) was identified as one possibl

42 In contrast, the activity of elongation factor G (EF-G) was strongly impaired in alph

43 ociation of elongation factor Tu (EF-Tu) and elongation factor G (EF-G) with the ribosome during prot

44 ation step of prokaryotic protein synthesis, elongation factor G (EF-G), a guanosine triphosphatase (

45 tion of the ribosome-recycling factor (RRF), elongation factor G (EF-G), and GTP to prepare the ribos

46 bosome-recycling factor (RRF), together with elongation factor G (EF-G), disassembles this posttermin

47 Tet(M) protein, which displays homology to elongation factor G (EF-G), interacts with the protein b

48 These proteins bind to elongation factor G (EF-G), the target of FA, and rescue

49 rotated state is not a proper substrate for elongation factor G (EF-G), thus inhibiting translocatio

50 elivers aminoacyl tRNAs to the ribosome, and elongation factor G (EF-G), which catalyzes translocatio

51 We observed significantly slower elongation factor G (EF-G)-catalyzed translocation throu

52 Cryo-EM reconstructions of certain elongation factor G (EF-G)-containing complexes have led

53 zed by the guanosine triphosphatase (GTPase) elongation factor G (EF-G).

54 drolysis on elongation factor Tu (EF-Tu) and elongation factor G (EF-G).

55 nslation by interfering with the function of elongation factor G (EF-G).

56 n of the ribosome-recycling factor (RRF) and elongation factor G (EF-G).

57 nslocation through the ribosome catalyzed by elongation factor G (EF-G).

58 anied by large interdomain rearrangements of elongation factor G (EF-G).

59 This reaction is catalyzed by elongation factor-G (EF-G) and is associated with riboso

60 Ribosome recycling factor (RRF) and elongation factor-G (EF-G) are jointly essential for rec

61 The ribosome-recycling factor (RRF) and elongation factor-G (EF-G) disassemble the 70S post-term

62 presence of the antibiotic thiostrepton and elongation factor-G (EF-G) rigorously localized the bind

63 ogenic bacteria Staphylococcus aureus, locks elongation factor-G (EF-G) to the ribosome after GTP hyd

64 R) of an orthologue of bacterial translation elongation factor G (EFG).

65 ional ribosome complexes and to compete with elongation factor G for interaction with pretranslocatio

66 of the small subunit head domain within the elongation factor G (GDP)-bound ribosome complex.

67 domains could facilitate the association of elongation factor-G into lipid rafts in living bacteria,

68 As a homolog of elongation factor G, it contains three domains (III-V) p

69 o observe aa-tRNA accommodation coupled with elongation factor G-mediated translocation.

70 Mitochondria possess two elongation factor Gs: one with translocation activity (E

71 We can position either elongation factor G or elongation factor Tu complexed wi

72 The overproduction of elongation factor G or initiation factor 3 did not have

73 m the A to the P-site upon GTP hydrolysis by elongation factor G, shifting approximately 8 A toward t

74 domain (L11-NTD) may variously interact with elongation factor G, the antibiotic thiostrepton, and rR

75 In the absence of elongation factor G, the entire pretranslocation ribosom

76 recycling factor (RRF) is used together with elongation factor G to recycle the 30S and 50S ribosomal

77 mal protein S5 and the ribosomal translocase elongation factor G, which suggests evolution from a com

78 d also shows time-dependent enhancement when elongation factor G with GTP is added to 70S ribosomes.