ライフサイエンスコーパス: embryoid

1 ), and differentiated cells via formation of embryoid bodies (16, 20 days) were analyzed.

2 e cell suspensions obtained from day 7 human embryoid bodies (d7EBs) injected i.v. 1 hour after cecal

3 s study, using ESC derived aggregates called embryoid bodies (EB) as a model, we characterized the bi

4 yonic stem (ES) cells were differentiated as embryoid bodies (EBs) and assayed for blast colony-formi

5 bstrates generate size- and shape-controlled embryoid bodies (EBs) and can be easily modified to cont

6 mically defined medium supports formation of embryoid bodies (EBs) and differentiation of hepatic lin

7 We found that ERbeta was induced in embryoid bodies (EBs) and neural precursor cells (NPCs)

8 (VE-cadherin)-expressing cells generated in embryoid bodies (EBs) and on OP9 cells.

9 iation, as seen in poorly differentiated TKO embryoid bodies (EBs) and teratomas.

10 at hTERT silencing during differentiation to embryoid bodies (EBs) and to fibroblast-like cells was d

11 , we used embryonic stem cell-differentiated embryoid bodies (EBs) as a model and found that Bnip3 (B

12 dy we used mouse embryonic stem cell-derived embryoid bodies (EBs) as a model for peri-implantation d

13 S) cells can differentiate in vitro, forming embryoid bodies (EBs) composed of derivatives of all thr

14 Embryoid bodies (EBs) derived from cells lacking the aut

15 e stages of ExEn differentiation in cultured embryoid bodies (EBs) derived from either embryonic stem

16 Compared to wildtype (WT) controls, embryoid bodies (EBs) derived from either Lefty or Cerb-

17 Measuring the Shh response in neuralized embryoid bodies (EBs) derived from embryonic stem (ES) c

18 n, calponin, and LPP, were down-regulated in embryoid bodies (EBs) derived from embryonic stem cells

19 Here we demonstrate that embryoid bodies (EBs) differentiated from talin1-null em

20 cadherin positive cells developed within the embryoid bodies (EBs) formed by differentiating ES cells

21 ut embryonic stem cells (VIM -/- ESCs) using embryoid bodies (EBs) formed from both cell types.

22 Embryoid bodies (EBs) generated from embryonic stem cell

23 Wnt2(-/-) embryoid bodies (EBs) generated increased numbers of Flk

24 te into cell types of all germ layers within embryoid bodies (EBs) in a highly variable manner.

25 endoderm following their differentiation to embryoid bodies (EBs) in culture.

26 describe the internal organization of murine embryoid bodies (EBs) in terms of the structures and cel

27 tiating ES cells into cardiomyocyte-positive embryoid bodies (EBs) in vitro.

28 Rac1 ablation in embryonic stem cell-derived embryoid bodies (EBs) leads to massive apoptosis of epib

29 arge numbers of homogeneous and synchronized embryoid bodies (EBs) of defined sizes from dissociated

30 lls was dramatically delayed and impaired in embryoid bodies (EBs) of Shp-2 mutant origin.

31 c stem (ES) cells as they differentiate into embryoid bodies (EBs) or into extraembryonic endodermal

32 Here, we differentiated mouse iPSCs into embryoid bodies (EBs) or representative cell types spann

33 Expression of RUNX1a in embryoid bodies (EBs) promotes definitive hematopoiesis

34 h endogenous nuclear huntingtin in wild-type embryoid bodies (EBs) was associated with PRC2 subunits

35 oximately 65%) of cocultured ES cell-derived embryoid bodies (EBs) were enriched in cardiac myocytes

36 l patterning signals, murine ES cell-derived embryoid bodies (EBs) were grafted into avian hosts.

37 m and abnormal PPAR-gamma pathway in beating embryoid bodies (EBs) with defined media, we established

38 ES cells were allowed to differentiate into embryoid bodies (EBs), compared to the wild-type and het

39 peptide to the media enhanced the growth of embryoid bodies (EBs), increased the expression of hemat

40 Upon ES cell differentiation into embryoid bodies (EBs), we observed a shift in expression

41 In vitro, ES cells aggregate to form embryoid bodies (EBs), which differentiate into multiple

42 rmation of multicellular aggregates known as embryoid bodies (EBs), yet cell fate specification withi

43 affected by the size of ES cell colonies and embryoid bodies (EBs).

44 enerated in embryonic stem (ES) cell-derived embryoid bodies (EBs).

45 ions of hES-CMs in spontaneously contracting embryoid bodies (EBs).

46 arliest surface marker missing from SCL(-/-) embryoid bodies (EBs).

47 elopment in embryonic stem (ES) cell-derived embryoid bodies (EBs).

48 nd definitive erythromyelopoiesis from human embryoid bodies (hEBs) in serum-free clonogenic assays.

49 , we generated genetically mosaic neuralized embryoid bodies (nEBs) from mouse embryonic stem cells (

50 ricle with 40 to 75 rhythmically contracting embryoid bodies (totaling 1.3-2x10(6) cells).

51 lished from in vitro-differentiated progeny (embryoid bodies [EBs]) of embryonic stem (ES) cells usin

52 ditions and the avoidance of feeder cells or embryoid bodies allowed synchronous and reproducible dif

53 apoptosis-dependent process of cavitation in embryoid bodies and apoptosis associated with embryonic

54 tro differentiation potentials of iPSCs into embryoid bodies and different hematopoietic cell types.

55 Pten-/- ES cells formed aberrant embryoid bodies and displayed an altered ability to diff

56 how that Bmp2 and Bmp4 are expressed in PSA1 embryoid bodies and embryos at the stages when visceral

57 Upon differentiation into embryoid bodies and further into mineral-producing osteo

58 on of flk1(+) angioblasts in differentiating embryoid bodies and increased the number of PECAM (plate

59 is repressed as ES cells differentiate into embryoid bodies and is undetectable in adult mouse organ

60 rs while increasing the numbers of secondary embryoid bodies and mixed hematopoietic colonies obtaine

61 Although embryoid bodies and organoids can exhibit some spatial o

62 o the NA extract enhanced differentiation of embryoid bodies and resulted in the early appearance of

63 haracterized by vigorous beating activity of embryoid bodies and robust expression of cardiac Mef2c,

64 em cell markers; have the capability to form embryoid bodies and teratomas, and can differentiate int

65 ro, pig-a- ES cells were able to form pig-a- embryoid bodies and to undergo hematopoietic (erythroid

66 naling assay; 3) Pofut1(-/-) and Pofut1(+/+) embryoid bodies are indistinguishable in their ability t

67 cells before and during differentiation into embryoid bodies as well as various types of normal and t

68 mouse ES cells and that FAK signaling within embryoid bodies can direct stem cell lineage commitment.

69 Immunohistochemical analysis of embryoid bodies collected from these cultures revealed a

70 tiate in vitro into cystic structures called embryoid bodies consisting of tissue lineages typical of

71 Embryonic stem cell-derived embryoid bodies contain a unique precursor population wh

72 Nodal-expressing hESCs developing as embryoid bodies contained an outer layer of visceral end

73 A study using embryoid bodies demonstrated a nonimmediate role played

74 Embryoid bodies derived from embryonic stem cells recapi

75 s also different from the null phenotype, as embryoid bodies derived from ES cells in which endogenou

76 Differentiated embryoid bodies derived from GATA6(-/-) ES cells lack a

77 ind that hematopoietic CD34(+) cells in spin embryoid bodies derived from human embryonic stem cells

78 We demonstrate that embryoid bodies derived from KLF2(-)(/)(-) ES cells can

79 In this study, we used differentiating embryoid bodies derived from mouse embryonic stem cells

80 The embryoid bodies derived from mutant cells are also unabl

81 Embryoid bodies derived from these cell lines are unable

82 and impaired primitive ectoderm formation in embryoid bodies differentiated from mouse embryonic stem

83 zyme activity occurring at later stages when embryoid bodies differentiated toward cardiomyocytes.

84 Levels of Neu5Gc on HESC and embryoid bodies dropped after culture in heat-inactivate

85 Pharmacological responses of beating embryoid bodies exposed to a comprehensive panel of drug

86 Flk-1(+) Tet-notch4 cells from d 3 embryoid bodies exposed to doxycycline (Dox(+)) were com

87 with retinoic acid, the majority of cells in embryoid bodies expressed markers for neural progenitors

88 -1alpha/ARNT heterodimers) because Arnt(-/-) embryoid bodies fail to exhibit hypoxia-mediated progeni

89 g Ptp gamma antisense constructs and assayed embryoid bodies for the presence of hematopoietic precur

90 nd growth factors by ESCs differentiating as embryoid bodies for up to 14 days was assessed using PCR

91 Differentiating embryoid bodies form blood islands, providing an in vitr

92 roarrays to identify targets of Brachyury in embryoid bodies formed from differentiating mouse ES cel

93 lar criteria in the outer PE-like lineage of embryoid bodies formed from embryonic stem cell lines ge

94 S) cells made extensive skeletal muscle, but embryoid bodies from myogenin (-/-) ES cells had greatly

95 oderm, which are prominent features of early embryoid bodies from normal ES cells.

96 Differentiated embryoid bodies from wild-type embryonic stem (ES) cells

97 ree media, human embryonic-stem-cell-derived embryoid bodies generate a KDR(low)/C-KIT(CD117)(neg) po

98 ultipotential precursor that develops within embryoid bodies generated from differentiated ES cells.

99 C development, spontaneously differentiating embryoid bodies give rise to CD105(+)CD90(+)CD73(+)CD31(

100 imitive endoderm cells of the outer layer of embryoid bodies gradually polarise, and formation of a p

101 irst appeared in embryonic stem cell-derived embryoid bodies grown for 7 days (7d).

102 Moreover, A(-)/A(-) embryoid bodies grown in suspension culture constantly s

103 ent development of keratinocytes from single embryoid bodies in cell culture.

104 re functionally abnormal; they yielded small embryoid bodies in in vitro differentiation experiments

105 The ES cell line D3 forms embryoid bodies in suspension culture without addition o

106 Cells cultured in HESCO readily form embryoid bodies in tissue culture and teratomas in mice.

107 AdiPS cells also generate embryoid bodies in vitro and teratomas in vivo.

108 cardiac differentiation was recapitulated in embryoid bodies in vitro.

109 n by HNF-3alpha and HNF-3beta was studied in embryoid bodies in which one or both HNF-3alpha or HNF-3

110 at addition of BMP protein to cultures of S2 embryoid bodies induces expression of Hnf4 and other vis

111 levels of unbound histones, and formation of embryoid bodies is accelerated.

112 dent differentiation of endothelial cells in embryoid bodies is also antagonized by BMPER.

113 system, we found that induction of VEGFR1 in embryoid bodies is also associated with ETS1 and HIF-2al

114 Studies of morphogenesis in embryoid bodies led to the current belief that it is pro

115 nd MyoD to support muscle differentiation in embryoid bodies made from myogenin (-/-) ES cells.

116 Like ES cells, embryoid bodies maintained constitutive Src and Fyn kina

117 Both HESC and derived embryoid bodies metabolically incorporate substantial am

118 patic differentiation protocol starting from embryoid bodies of hiPSCs (hiPSC-EBs) for robust mass pr

119 up to 200 microm within 1 day of plating P19 embryoid bodies on laminin-1 (EHS laminin).

120 (LIF) and could initiate differentiation in embryoid bodies or chimeric embryos, but failed to commi

121 tides (DR1, DR2, DR5), we show that in mouse embryoid bodies or F9 embryonal carcinoma cells, RARs oc

122 Whether formed from embryoid bodies or in nodules, hES-derived keratinocytes

123 differentiated cells, methods that generate embryoid bodies or organoids do not yield consistent and

124 re, which does not require the generation of embryoid bodies or prospective cell isolation, entails f

125 actor-beta treatment of isolated N629D/N629D embryoid bodies partially rescued this phenotype.

126 In particular, embryoid bodies produced from these Pgk-Pem ES cells do

127 4+ cells during ES cell differentiation from embryoid bodies provides an excellent model system and m

128 ction of mMix in embryonic stem cell-derived embryoid bodies results in the early activation of mesod

129 microscopy of cardiomyocytes in the Gata4-/- embryoid bodies revealed the presence of sarcomeres and

130 ne embryonic stem cells converted to beating embryoid bodies showed that only the proximal active reg

131 mbryos and mouse embryonic stem cell-derived embryoid bodies substantially decrease the emergence of

132 differentiation of mouse embryos and ES cell embryoid bodies suggest that aspects of early mammalian

133 these cells were induced to differentiate as embryoid bodies suggested that quite a few of the downre

134 We show that embryoid bodies support maturation of the primordial ger

135 Because embryoid bodies sustain blood development, we reasoned t

136 Embryoid bodies that are cultured in the presence of nep

137 hibitory factor, mouse ES cells give rise to embryoid bodies that can differentiate into mesoderm.

138 e previously used two cell lines, which form embryoid bodies that do (PSA1) or do not (S2) cavitate,

139 When aggregated into embryoid bodies they develop disorganised masses of diff

140 that (a) laminin enables beta1-integrin-null embryoid bodies to assemble basement membrane and achiev

141 Finally, exposure of stem cell-derived human embryoid bodies to hsa-miR-1294 mimic or antagomir oligo

142 anging drop embryoid bodies, and adhesion of embryoid bodies to surfaces at or before that day strong

143 We exposed stem cell-derived human embryoid bodies to the microRNA mimic or antagomir oligo

144 IF-deficient cells and enabled AIF-deficient embryoid bodies to undergo cavitation, a process of prog

145 ctopic beats were observed in 33% and 40% of embryoid bodies treated with sotalol and quinidine, resp

146 Differentiation of ES cells to embryoid bodies was associated with rapid transcriptiona

147 a dominant negative FAK, cell migration from embryoid bodies was inhibited, whereas alpha-myosin heav

148 n of this pathway in the primitive endoderm, embryoid bodies were cultured in the presence of a small

149 METHODS AND Embryoid bodies were derived from human keratinocytes, t

150 mRNA levels induced upon differentiation to embryoid bodies were down-regulated in homozygous null H

151 suppress cardiogenesis through Src kinases, embryoid bodies were exposed to the small molecule PP2,

152 organogenesis protocol was optimised whereby embryoid bodies were formed and patterned towards an eye

153 The outer cells of these embryoid bodies were found to gradually acquire the hall

154 e cloning efficiency and the ability to form embryoid bodies were restored in embryonic stem cells, i

155 ment membrane assembly was also evaluated in embryoid bodies where it was found that both LG1-3 and L

156 hat defined differentiation of ES cells into embryoid bodies with Activin-A and selection for T expre

157 They produce embryoid bodies with elevated levels of the primitive en

158 Incubation of embryoid bodies with the vital dye, Dil, revealed the pe

159 during differentiation of ES cells in vitro (embryoid bodies) and in vivo (teratomas).

160 tes were seen in both wild-type and Gata4-/- embryoid bodies, although cardiomyocytes were observed m

161 lpha5-null ES cells were differentiated into embryoid bodies, although they were delayed in growth an

162 ere first expressed at day 4 in hanging drop embryoid bodies, and adhesion of embryoid bodies to surf

163 re differentiated into cardiomyocytes within embryoid bodies, and contracting cells expressing myocar

164 Here we isolate primordial germ cells from embryoid bodies, and derive continuously growing lines o

165 d spontaneous differentiation in cultures of embryoid bodies, and each of these steps involves signif

166 ized with flk1 expression in differentiating embryoid bodies, and HoxB5 potently transactivated the f

167 e hematopoietic stem cell differentiation in embryoid bodies, and large embryonic stem cell (ES)-deri

168 gocytosis were detected in PU.1(Spi-B/Spi-B) embryoid bodies, and myeloid colonies were present in he

169 progenitor cells present in differentiating embryoid bodies, and that these correspond to erythro-my

170 mesodermal lineages do not form in Wt1-null embryoid bodies, but this effect is rescued by the expre

171 inoic acid, into either parietal endoderm or embryoid bodies, containing an outer visceral endoderm l

172 Upon aggregation to embryoid bodies, differentiating ES cells formed large n

173 layed a significant reduction in activity in embryoid bodies, embryos, and adult animals.

174 cultivation in vitro as 3D aggregates called embryoid bodies, ES cells can differentiate into derivat

175 The ID6 line formed embryoid bodies, expressing genes representing all 3 ger

176 different culture systems: FAK+/+ and FAK-/- embryoid bodies, FAK+/+ and FAK-/- endothelial cells, an

177 ion of a primitive streak-like population in embryoid bodies, followed by specification to hematopoie

178 Embryoid bodies, formed from mouse embryonic stem cells,

179 ) cell line H9, when cultured in the form of embryoid bodies, give rise to cells with markers of the

180 e was also reproduced in beta1 integrin-null embryoid bodies, in which primitive endoderm cells segre

181 stem cells compromised their ability to form embryoid bodies, likely because of defects in cell proli

182 lated during development of Nodal-expressing embryoid bodies, nor was there induction of markers for

183 The inducible expression of EWS-FLI1 in embryoid bodies, or collections of differentiating stem

184 ighted morphogenic cell processes within the embryoid bodies, such as cell growth, migration, and int

185 From day-6 embryoid bodies, under the influence of Stat5 signaling,

186 wly developed loss-of-function technology in embryoid bodies, we find that Gata2 and Smad5 cooperate

187 hen slowly decreased upon differentiation to embryoid bodies, whereas 5-methylcytosine levels increas

188 ed for protocols based on stromal feeders or embryoid bodies.

189 tion was substantially blunted in Gsk3b(-/-) embryoid bodies.

190 o S phase and mES cells differentiating into embryoid bodies.

191 to promote vascular development in Fgfr1-/- embryoid bodies.

192 ce positioning in Dab2-deficient embryos and embryoid bodies.

193 form a primitive endoderm outer layer in the embryoid bodies.

194 under hypoxia provided enhanced formation of embryoid bodies.

195 icient at generating neurectoderm-containing embryoid bodies.

196 othelial cell precursors in developing mouse embryoid bodies.

197 LK1(+)CD4(-) cells first arise in developing embryoid bodies.

198 mechanism is also adopted in differentiated embryoid bodies.

199 vivo and in embryonic stem (ES) cell-derived embryoid bodies.

200 arker, Hnf4, and prevents cavitation in PSA1 embryoid bodies.

201 tion of, visceral endoderm and cavitation of embryoid bodies.

202 ion factors in nuclear extracts from ES cell embryoid bodies.

203 ptional regulation in murine ES cell-derived embryoid bodies.

204 lian embryogenesis can be studied in ES cell embryoid bodies.

205 for the formation of a basement membrane in embryoid bodies.

206 formed a complex neurite network around the embryoid bodies.

207 xic Hif1a-/- embryonic stem cells and cystic embryoid bodies.

208 erved more often in wild type than in mutant embryoid bodies.

209 tion both in ES cells and in differentiating embryoid bodies.

210 ection neurons in monolayer culture and from embryoid bodies.

211 as a floating scaffold to generate elongated embryoid bodies.

212 ronal differentiation and the utilization of embryoid bodies.

213 by loss-of-function experiments in chimeric embryoid bodies.

214 type and mutant ES cells and differentiating embryoid bodies.

215 ive vascular network from SIRT1(-/-)-derived embryoid bodies.

216 Here, a live stem cell derived embryoid body (EB) based cardiac cell syncytium served a

217 d development by means of coculture of CD34+ embryoid body (EB) cells with OP9 stromal cells.

218 ) hPGCLCs [ approximately 43% of FACS-sorted embryoid body (EB) cells] from primed-state induced plur

219 ental patterns of cellular expression during embryoid body (EB) differentiation can address this issu

220 jnk3 genes were derived and submitted to an embryoid body (EB) differentiation protocol.

221 The process of embryoid body (EB) differentiation, like teratoma format

222 of cells present at early and late stages of embryoid body (EB) differentiation.

223 We differentiated hESCs by embryoid body (EB) formation and compared the miR expres

224 Embryoid body (EB) formation is a requisite step in the

225 val, using annexin V staining, and secondary embryoid body (EB) formation were also evaluated.

226 to decreased pluripotency marker expression, embryoid body (EB) formation, cell survival, and loss of

227 l fate at the expense of the endoderm during embryoid body (EB) formation.

228 er capacity to self-renew based on secondary embryoid body (EB) formation.

229 gnificant haploinsufficient determinants for embryoid body (EB) formation.

230 aucity of paraxial mesoderm formation during embryoid body (EB) in vitro differentiation and to the l

231 S and ES cells were differentiated using the embryoid body (EB) method.

232 h the number and the size of beating foci in embryoid body (EB) outgrowths.

233 em (ES) cells undergo differentiation in the embryoid body (EB) system, with peak levels in cell popu

234 stablishment of the blood islands and in the embryoid body (EB)-derived blast-colony-forming cells (B

235 To improve the efficiency of embryoid body (EB)-mediated ES cell differentiation, we

236 PP2 during embryoid body adhesion dramatically increased cardiomyoc

237 as the TaqMan hPSC Scorecard Assay) through embryoid body and directed differentiation experiments a

238 o iPSCs and differentiated into iPSC-CMs via embryoid body and monolayer-based differentiation protoc

239 he activation of developmental regulators in embryoid body assays.

240 activated cell sorting purification of human embryoid body cells differentially expressing endothelia

241 t the growth or viability of ES cell-derived embryoid body cells known to have extinguished TDH expre

242 on of primitive ectoderm and neurectoderm in embryoid body culture.

243 Depletion of Smad1 in embryoid body cultures before hemangioblast commitment l

244 We find that in embryoid body cultures containing even a low ratio of th

245 Using embryoid body cultures of mouse embryonic stem cells, we

246 1 in ES cells and used ES/OP-9 coculture and embryoid body development followed by hematopoietic colo

247 at develops early and is lost quickly during embryoid body development.

248 In an embryoid body differentiation assay, BMP4-dependent diff

249 sion of the transcription factor Pax3 during embryoid body differentiation enhances both paraxial mes

250 nd endothelial progenitor cells by using the embryoid body differentiation method.

251 Using the embryoid body differentiation system, we demonstrate tha

252 ematopoietic lineage (from day 4 to day 6 of embryoid body differentiation) significantly enhances th

253 a) gene between 14 and 18 days of ES-derived embryoid body differentiation, we investigated the effec

254 illary-like structures during late stages of embryoid body differentiation.

255 ce markers, and differentiation potential in embryoid body formation and teratoma assays.

256 ed pluripotent stem cells (hiPSC), bypassing embryoid body formation and the use of exogenous molecul

257 of ectodermal and mesodermal lineages during embryoid body formation and under inductive conditions u

258 l direct plating method in which intervening embryoid body formation does not occur.

259 into multiple hematopoietic lineages during embryoid body formation in vitro, but to date, an ES-der

260 s required embryoid body formation; however, embryoid body formation often results in heterogeneous d

261 Data from embryoid body formation studies indicated that the Mp(-/

262 Embryoid body formation yielded beating cardiomyocyte-li

263 ed almost 30-fold during the first 3 days of embryoid body formation, a culture system model of early

264 ifferent in vitro differentiation protocols (embryoid body formation, endodermal induction, directed

265 for human embryonic stem (hES) cells rely on embryoid body formation, stromal feeder co-culture or se

266 ariants prevents the switch and disrupts the embryoid body formation.

267 ull differentiation capacity as indicated by embryoid body formation.

268 ted Nanog levels persisted through 5 days of embryoid body formation.

269 ifferentiation of ES cells in the absence of embryoid body formation.

270 ES cells overlapped with the changes during embryoid body formation.

271 ation from sorted single cells, and enhanced embryoid body formation.

272 ion of chondrogenesis by human ESCs required embryoid body formation; however, embryoid body formatio

273 The developmental sequence of human embryoid body hematopoiesis is remarkably congruent to t

274 cells into endothelial cells in an in vitro embryoid body is paralleled by an amplification of hepar

275 human iPS clones were differentiated through embryoid body method and MYF5-GFP(+) myogenic cells were

276 Using a modified embryoid body method, we provided gene expression eviden

277 eased on differentiation into differentiated embryoid body or neurospheres.

278 n vitro using the F9 teratocarcinoma derived embryoid body outgrowth system and, show here that PE mi

279 nalyses, we used an inducible embryonic stem/embryoid body system and observed that ER71 overexpressi

280 hat utilizes the differentiating ES cell and embryoid body system to define the modules and enhancers

281 e ES cells than in differentiating mouse ES (embryoid body, EB) cells.

282 r cell, serum, conditioned culture medium or embryoid body, methods that cannot avoid undefined cultu

283 lly undefined factors including 3D nature of embryoid body, sera from animals, and the feeder cells i

284 For example, embryoid body-based analyses demonstrated that BAF250a-a

285 ls derived from embryonic germ cells, termed embryoid body-derived (EBD) cells, introduced into the C

286 undifferentiated embryonic stem (ES) cells, embryoid body-derived cells (EBCs), or mammalian embryos

287 ntification and characterization of an early embryoid body-derived colony, termed the transitional co

288 We show that embryoid body-derived hematopoietic progenitors expressi

289 In this study, the osteoinductivity of embryoid body-derived material (EBM) was compared to DBM

290 onal mutation, and has been termed EB-PE for embryoid body-derived primitive erythroid.

291 We sought to use human embryoid body-derived stem cells (EBDs) to populate live

292 ive splice variant CoAM in the cavity of the embryoid body.

293 alable two-dimensional method that avoids an embryoid-body intermediate.

294 in mouse embryonic stem cells and from human embryoid-body-derived cells, but not from human adult so

295 Remarkably, anchorage of the embryoid colony from the 3D matrix to collagen-1-coated

296 By taking advantage of this ability, embryoids, organoids and gastruloids have recently been

297 l, termed the post-implantation amniotic sac embryoid (PASE), that recapitulates multiple post-implan

298 mately 7 hours postfertilization resulted in embryoids that displayed oral-aboral axis patterning in

299 nd aboral ectoderm, developed into polarized embryoids that expressed an oral ectoderm-specific marke

300 l, termed the post-implantation amniotic sac embryoid, to recapitulate early embryogenic events of hu