ライフサイエンスコーパス: embryonic fibroblast

1 tumor cells and in the Ras-transformed mouse embryonic fibroblasts.

2 is determined by the number and position of embryonic fibroblasts.

3 y feature of Tet1/Tet2 double-knockout mouse embryonic fibroblasts.

4 l-time transport of beta-actin mRNA in mouse embryonic fibroblasts.

5 s-links in Fkbp10-null and -wild-type murine embryonic fibroblasts.

6 to normally dividing Schwann cells or mouse embryonic fibroblasts.

7 l virus in monkey epithelial cells and mouse embryonic fibroblasts.

8 ntiation is increased in Id1-deficient mouse embryonic fibroblasts.

9 radioresistant compared with wild-type mouse embryonic fibroblasts.

10 ines: human embryonic kidney cells and mouse embryonic fibroblasts.

11 cell death in Bax/Bak1 double-deleted mouse embryonic fibroblasts.

12 survival in hyperosmotically stressed mouse embryonic fibroblasts.

13 tcomes in Rab11a(null) blastocysts and mouse embryonic fibroblasts.

14 ent structures during reprogramming of mouse embryonic fibroblasts.

15 12, or 14 in tetraploid immortalized murine embryonic fibroblasts.

16 PGC-1alpha modulates the secretome of mouse embryonic fibroblasts.

17 gene- and transcript-targeted primary mouse embryonic fibroblasts.

18 adipogenesis is enhanced in Rnf146-/- mouse embryonic fibroblasts.

19 with wild-type and pol kappa deficient mouse embryonic fibroblasts.

20 not K-Ras(G12V) induced senescence in mouse embryonic fibroblasts.

21 n intermediate between pro-B cells and mouse embryonic fibroblasts.

22 hance copper accumulation in Ctr1(-/-) mouse embryonic fibroblasts.

23 chromatin structure of Ku70-deficient mouse embryonic fibroblasts.

24 tion density in transcription units in mouse embryonic fibroblasts also correlated strongly with intr

25 Flux assays in Mpc1-deficient embryonic fibroblasts also reflected these changes, incl

26 Utilizing mouse embryonic fibroblast and cancer cell line models, here w

27 We found that Plp2-deficient mouse embryonic fibroblast and human fibroblasts carrying PLP2

28 ck hypoxia-induced Fbln5 expression in mouse embryonic fibroblasts and 3T3 fibroblasts.

29 mming efficiency of adult-derived but not of embryonic fibroblasts and also enhanced functional matur

30 biting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth o

31 y 10000 regions of OG enrichment in WT mouse embryonic fibroblasts and approximately 18000 regions wh

32 We validate our method by imaging mouse embryonic fibroblasts and BON cells.

33 reduced colony formation of Fan1(-/-) mouse embryonic fibroblasts and bone marrow mesenchymal stem c

34 sion is markedly reduced in TAp63-null mouse embryonic fibroblasts and brown adipose tissues and by t

35 nd increases susceptibility to cell death in embryonic fibroblasts and cardiac myocytes.

36 severity and infectivity in primary chicken embryonic fibroblasts and chickens.

37 ed the Hh pathway in both Hh-dependent mouse embryonic fibroblasts and cultured cancer cells (IC50 va

38 to be SIRT1-dependent in proliferating mouse embryonic fibroblasts and differentiating human SW872 pr

39 assays were performed with IQGAP1-null mouse embryonic fibroblasts and HEK293 cells with IQGAP1 knock

40 tion were normal in Clec16a-deficient murine embryonic fibroblasts and HeLa cells.

41 level, Brpf1 loss inhibits proliferation of embryonic fibroblasts and hematopoietic progenitors.

42 by 3-16 folds in primary mouse macrophages, embryonic fibroblasts and human cell lines.

43 ontin and other FN-type matrix in both mouse embryonic fibroblasts and human melanoma.

44 utant Kras homozygous and heterozygous mouse embryonic fibroblasts and lung cancer cells, that these

45 ogical or genetic inhibition of ILK in mouse embryonic fibroblasts and macrophages selectively blocks

46 This phenotype was also seen in both mouse embryonic fibroblasts and mesangial cells.

47 Investigation using Dab2-deficient embryonic fibroblasts and mesenchymal stromal cells indi

48 ol and tumor suppression, we generated mouse embryonic fibroblasts and mice expressing a mutant pRB p

49 ng endosomes is significantly reduced in Loa embryonic fibroblasts and motor neurons.

50 Using genetic deficiencies in mouse embryonic fibroblasts and mouse liver, we identified the

51 Furthermore, Reep1-/- embryonic fibroblasts and neurons in the cerebral cortex

52 G12V))-induced premature senescence in mouse embryonic fibroblasts and normal human bronchial epithel

53 s, and Ets2 is sufficient to reprogram mouse embryonic fibroblasts and post-natal tail-tip-derived fi

54 Cytogenetic analysis of mouse embryonic fibroblasts and pre-malignant B cells demonstr

55 ) stabilization in cultured Pink1(-/-) mouse embryonic fibroblasts and primary cortical neurons as we

56 dramatic induction of many neuronal genes in embryonic fibroblasts and primary DSRCT, most notably th

57 n of IP3R3 is accelerated in Pten(-/-) mouse embryonic fibroblasts and PTEN-null cancer cells.

58 When overexpressed in both mouse embryonic fibroblasts and rat OPCs (rOPCs), cell cycle a

59 ogen-driven immortalization of primary mouse embryonic fibroblasts and recapitulates early steps of c

60 rus replication in both HeLa cells and mouse embryonic fibroblasts and that its influence is exercise

61 ized dimensions, surrounded by 3T3-J2 murine embryonic fibroblasts, and then sandwiched with a thin l

62 ic approach showed that ARH3-deficient mouse embryonic fibroblasts are characterized by a specific in

63 Consistently, AIP-deficient murine embryonic fibroblasts are highly resistant to virus infe

64 il chromatin accessibility dynamics as mouse embryonic fibroblasts are reprogrammed into induced plur

65 We used mouse embryonic fibroblasts as a system to determine the effec

66 overed new roadblocks in reprogramming mouse embryonic fibroblasts as pluripotent stem cells, disting

67 istic target of rapamycin signaling in mouse embryonic fibroblasts as well as in muscle and liver tis

68 system to delete FIP200 in transformed mouse embryonic fibroblasts as well as mammary tumor cells fol

69 present evidence from mouse brain tissue and embryonic fibroblasts as well as patient skin fibroblast

70 In the case of mouse embryonic fibroblasts, BER of the Sp lesion is strongly

71 w that, to perform these activities in mouse embryonic fibroblasts, both proteins competitively heter

72 at Orai1 is a dimer in resting primary mouse embryonic fibroblasts but displays variable stoichiometr

73 Expression is not detected in C3H10T1/2 embryonic fibroblasts but is successively higher in preo

74 ly induces the cardiac gene program in mouse embryonic fibroblasts but not adult fibroblasts.

75 ratio was rescued in FKBP65-deficient murine embryonic fibroblasts by reconstitution with wild-type b

76 l structures of a mitochondrion from a mouse embryonic fibroblast cell line (NIH3T3) were visualized

77 h cAMP-CREB signaling pathways both in mouse embryonic fibroblast cells and in urinary and reproducti

78 er TEM8 was further demonstrated using mouse embryonic fibroblast cells and mice deficient in the CMG

79 6S proteasomes purified from wild-type mouse embryonic fibroblast cells and those lacking Usp14.

80 usly (3T9) or virus-(SV40) transformed mouse embryonic fibroblast cells as targets.

81 Interestingly, in mouse embryonic fibroblast cells derived from CIZ1-null embryo

82 We investigated this question using mouse embryonic fibroblast cells expressing wild-type PKR (PKR

83 We report here that murine embryonic fibroblast cells from ZAP knockout mice suppor

84 Knockout of GSK3beta in mouse embryonic fibroblast cells increases expression of miR-9

85 s was not affected in SV40-transformed mouse embryonic fibroblast cells lacking Bak/Bax.

86 Although S187A mouse embryonic fibroblast cells showed normal proliferation u

87 D-induced differentiation of 4.1R(-/-) mouse embryonic fibroblast cells.

88 glycolytic products in both tumor and mouse embryonic fibroblast cells.

89 (WT) and Bcl-xL knock-out (Bcl-xL-KO) mouse embryonic fibroblast cells.

90 nor fraction (30-40%) of the 26S in WT mouse embryonic fibroblast cells.

91 Mouse embryonic fibroblasts challenged with TPZ or Cu(OP)2 als

92 tion but is dispensable for kidney and mouse embryonic fibroblast ciliary formation.

93 88/IFN-beta promoter stimulator 1(-/-) mouse embryonic fibroblasts completely lacked antiviral activi

94 Analysis of wounds and mouse embryonic fibroblast cultures showed that EMILIN-1 and -

95 WT KRAS to rescue the growth defect of mouse embryonic fibroblasts deficient in all Ras genes.

96 Here we show that mouse embryonic fibroblasts deficient in Bax/Bak1 are resistan

97 t-myocardial infarction hearts, and in mouse embryonic fibroblasts deleted for GSK-3beta.

98 In embryonic fibroblasts derived from ATGL KO mice, exogeno

99 In vitro experiments using cultured embryonic fibroblasts derived from IFN receptor knockout

100 y relevant to microtubule dynamics, as mouse embryonic fibroblasts derived from LRRK2 knock-out mice

101 Nphp5(-/-) mouse embryonic fibroblast developed normal cilia, and Nphp5(-

102 Interestingly, Msh3(-/-) mouse embryonic fibroblasts displayed increased chromatid brea

103 Primary embryonic fibroblasts double homozygous for Mcm4chaos3 a

104 ecreased senescence of hepatocytes and mouse embryonic fibroblasts, effects that were blocked by trea

105 was upregulated in Tsc1-/- or Tsc2-/- mouse embryonic fibroblasts, Eker rat uterine leiomyoma-derive

106 eep sequencing of small RNA molecules in the embryonic fibroblasts, embryonic stem cells, and induced

107 RepID-depleted murine embryonic fibroblasts exhibit abnormal replication fork

108 in Dhrs3(-/-) embryos, and Dhrs3(-/-) mouse embryonic fibroblasts exhibit reduced metabolism of both

109 Here, we discovered that Ate1-knockout (KO) embryonic fibroblasts exhibit tumorigenic properties, in

110 pry1(-/-) and Spry2(-/-) double mutant mouse embryonic fibroblasts exhibited decreased cell migration

111 that deletion of Ada3 from Ada3(FL/FL) mouse embryonic fibroblasts exhibited various chromosome segre

112 Whereas Bok(-/-) mouse embryonic fibroblasts exposed to thapsigargin, A23187, b

113 doses; however, in the Ku70-deficient mouse embryonic fibroblasts, exposure to a high dose of BPA wa

114 Tsc1(-/-) and Tsc2(-/-) mouse embryonic fibroblasts expressed higher uPA levels than t

115 lture platforms: feeder-free Matrigel, mouse embryonic fibroblast feeders, and Matrigel replated on f

116 Calnexin deficiency as studied in mouse embryonic fibroblasts from calnexin(-/-)mice or in respo

117 To elucidate such function(s), we generated embryonic fibroblasts from conditional epsin triple KO m

118 Experiments using embryonic fibroblasts from CyclinA2-LacZ-floxed-EGFP, or

119 -related GTPase (IRGM1) was overexpressed in embryonic fibroblasts from dynamin1 like (DNM1L) protein

120 mic reticulum (ER) stress response) in mouse embryonic fibroblasts from Epm2a(-/-), Epm2b(-/-), and E

121 Analysis of embryonic fibroblasts from GFP reporter mice indicates t

122 ed resistance to cell death, and (iii) mouse embryonic fibroblasts from IFN receptor 1 knockout mice

123 ignaling is significantly increased in mouse embryonic fibroblasts from mAnkrd6 knockout mice in comp

124 Here we used mouse embryonic fibroblasts from mice deficient in FAM134B to

125 epithelial tissues from patients with CD and embryonic fibroblasts from mice, along with enteroids an

126 on of reactive oxygen species were higher in embryonic fibroblasts from Mpv17(-/-) mice.

127 ility were observed at a higher frequency in embryonic fibroblasts from Neil2-null mice than from the

128 ysis of cultured mesoderm explants and mouse embryonic fibroblasts from null mutants shows that the m

129 IRGM1 was overexpressed in embryonic fibroblasts from receptor interacting serine/t

130 Employing mouse embryonic fibroblasts from wild-type and RGS6(-/-) mice,

131 eprogramming factor expression levels, mouse embryonic fibroblasts go through unique epigenetic modif

132 vestigate integrin beta3 and paxillin in rat embryonic fibroblasts growing on two different extracell

133 early adipocyte progenitors; however, their embryonic fibroblasts had approximately 50% lower adipoc

134 uced in Cln3(Deltaex1) (-) (6)-derived mouse embryonic fibroblasts have visibly disorganized membrane

135 d pluripotent stem cells (iPSCs) from murine embryonic fibroblasts, in the absence of p53.

136 ession of HH target genes in Sufu(-/-) mouse embryonic fibroblasts, in which constitutive Gli activit

137 f RhoA signaling-mediated processes in mouse embryonic fibroblasts, including stress fiber formation

138 function because ablation of SRPK1 in mouse embryonic fibroblasts induces cell transformation.

139 can sensitize breast cancer cells and mouse embryonic fibroblasts into entering paclitaxel-induced s

140 a or Rho-associated kinase pathways converts embryonic fibroblasts into functional cardiomyocyte-like

141 c-Myc) or Oct4 during reprogramming of mouse embryonic fibroblasts into iPSCs.

142 hat SV40 TAg-induced transformation in mouse embryonic fibroblasts is independent of activator E2Fs.

143 Furthermore, mouse embryonic fibroblasts isolated from TRPM7 kinase-dead an

144 Complementation experiments in mouse embryonic fibroblasts lacking beta-arrestins combined wi

145 B1 induces chromosomal instability in mouse embryonic fibroblasts lacking both Tp53 and Rb1.

146 e and NLS-mutated pol beta(R4S,K5S) in mouse embryonic fibroblasts lacking endogenous pol beta.

147 Analysis of replicating mitochondrial DNA in embryonic fibroblasts lacking RNase H1 reveals retention

148 experiments in cultured Oma1-deficient mouse embryonic fibroblasts link together impeded supercomplex

149 Herein, we demonstrated that, in mouse embryonic fibroblasts, loss of LKB1 and transduction of

150 on factor EB (TFEB) in RagA/B knockout mouse embryonic fibroblasts, lysosomal acidification is compro

151 associated with transcriptional silencing in embryonic fibroblasts, macrophages, and human embryonic

152 o-cultures (MPCCs) of PHHs and 3T3-J2 murine embryonic fibroblasts maintain insulin-sensitive glucose

153 E7) disrupts circadian oscillations in mouse embryonic fibroblasts, measured using PER2::Luc dynamics

154 biogenesis and function of EVs using a mouse embryonic fibroblast (MEF) cell line that can be induced

155 ion was also observed in Mfn2-knockout mouse embryonic fibroblast (MEF) cells as compared with the co

156 Here we label the endogenous Pol II in mouse embryonic fibroblast (MEF) cells using the CRISPR/Cas9 g

157 Using an established mouse embryonic fibroblast (MEF) model combining p53 inactivat

158 Using mouse embryonic fibroblast (MEF) models that generate inducibl

159 n inducible Raptor and Rictor knockout mouse embryonic fibroblast (MEF) system to further define the

160 36 trimethyltransferase SETD2 knockout mouse embryonic fibroblasts (MEF) cells.

161 Moreover, primary Rad18(-/-) mouse embryonic fibroblasts (MEF) retained robust Fancd2 mono-

162 in A2 deletion in oncogene-transformed mouse embryonic fibroblasts (MEF) suppressed tumor formation i

163 genes in both 3T3-L1 pre-adipocyte and mouse embryonic fibroblasts (MEF) upon exposure to a mixture o

164 E359K mouse embryonic fibroblasts (MEF) were more sensitive to DNA c

165 RNA and protein secretion in wild-type mouse embryonic fibroblasts (MEF).

166 formation using G0s2-null immortalized mouse embryonic fibroblasts (MEF).

167 sfecting MNV-1 RNA into IFN-stimulated mouse embryonic fibroblasts (MEFs) and bone marrow-derived den

168 racterized CENP-F(+/+) and CENP-F(-/-) mouse embryonic fibroblasts (MEFs) and found drastic differenc

169 impairs the proliferative potential of mouse embryonic fibroblasts (MEFs) and is associated with a si

170 correlated with H3K9me2 in interphase murine embryonic fibroblasts (MEFs) and is restricted to intrag

171 thylation (H3K27me3) in both Pten null mouse embryonic fibroblasts (MEFs) and Pten null mouse prostat

172 Rb in Cdk4(-/-) pituitary AL cells and mouse embryonic fibroblasts (MEFs) and rescues their prolifera

173 Mouse embryonic fibroblasts (MEFs) and retinal cells from Csnk

174 rated PCBP2-deficient mice and primary mouse embryonic fibroblasts (MEFs) and showed that loss of PCB

175 and represses fatty acid oxidation in mouse embryonic fibroblasts (MEFs) by targeting the AMP-activa

176 Trim13(-/-) murine embryonic fibroblasts (MEFs) challenged with EMCV or pol

177 nonmitochondrial PB2 is attenuated in mouse embryonic fibroblasts (MEFs) compared with an isogenic v

178 Murine embryonic fibroblasts (MEFs) deficient in PTPN12 underwe

179 Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three Tet ge

180 EGR1(-/-) mouse embryonic fibroblasts (MEFs) demonstrated lower suscepti

181 was absent in the conditioned media of mouse embryonic fibroblasts (MEFs) derived from Fam20a knock-o

182 re we show that primary adipocytes and mouse embryonic fibroblasts (MEFs) derived from FTO overexpres

183 We demonstrate that mouse embryonic fibroblasts (MEFs) derived from Hace1(-/-) mic

184 R was NF-kappaB-dependent, as shown in mouse embryonic fibroblasts (MEFs) derived from Rel null mice.

185 , we assessed H3K4me1 modification in murine embryonic fibroblasts (MEFs) derived from the DNA methyl

186 ow that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of int

187 Mechanistically, Tmem30a-mutant mouse embryonic fibroblasts (MEFs) exhibited diminished PS fli

188 lised cell lines derived from primary murine embryonic fibroblasts (MEFs) exposed in vitro to carcino

189 In this study, we show that, in mouse embryonic fibroblasts (MEFs) from Fut8(-/-) mice, anothe

190 cts of loss of NONO, we characterized murine embryonic fibroblasts (MEFs) from knockout mice.

191 cell cycle progression in immortalized mouse embryonic fibroblasts (MEFs) from PINK1(-/-) mice, and i

192 Using mouse embryonic fibroblasts (MEFs) from Tpcn1(-/-) and Tpcn2(-

193 ll4, Nanog, Esrrb, and Lin28 (SNEL) in mouse embryonic fibroblasts (MEFs) generated high-quality iPSC

194 nsistent with these results, Atf3(-/-) mouse embryonic fibroblasts (MEFs) had more aberrant chromosom

195 hat lysates from Nedd4-1 knockout (KO) mouse embryonic fibroblasts (MEFs) have significantly diminish

196 both breast cancer (BC) cell lines and mouse embryonic fibroblasts (MEFs) induces oversized cells con

197 can sensitize breast cancer cells and mouse embryonic fibroblasts (MEFs) into entering epirubicin-in

198 e tract binding protein PTB to convert mouse embryonic fibroblasts (MEFs) into functional neurons.

199 faceted effect on the reprogramming of mouse embryonic fibroblasts (MEFs) into induced pluripotent st

200 Proliferation of primary Ola1(-/-) mouse embryonic fibroblasts (MEFs) is impaired due to defectiv

201 50DblKo virus was rescued by growth on mouse embryonic fibroblasts (MEFs) isolated from IFN-alpha/bet

202 We examined glutamine metabolism in mouse embryonic fibroblasts (MEFs) isolated from mice that hav

203 The Cc2d2a(-/-) mouse embryonic fibroblasts (MEFs) lack cilia, although mother

204 Murine embryonic fibroblasts (MEFs) lacking Fyn and cells in wh

205 Primary mouse embryonic fibroblasts (MEFs) lacking the ARF tumor suppr

206 However, murine embryonic fibroblasts (MEFs) lacking TSC2 were highly re

207 Mouse embryonic fibroblasts (MEFs) or primary adult cardiac fi

208 Cebpg(-/-) mouse embryonic fibroblasts (MEFs) proliferate poorly and exhi

209 ffected individuals and Cdk10-knockout mouse embryonic fibroblasts (MEFs) proliferated normally; howe

210 c expression of DNMT3L in late-passage mouse embryonic fibroblasts (MEFs) recruited cytoplasmically l

211 C1qbp(-/-) mouse embryonic fibroblasts (MEFs) resembled the human disease

212 of PDAC cancer cells and SerpinB2(-/-) mouse embryonic fibroblasts (MEFs) resulted in increased tumou

213 ort that Cdc14B knockout (Cdc14B(-/-)) mouse embryonic fibroblasts (MEFs) showed defects in repairing

214 nerations, and immortalized TIN2(+/DC) mouse embryonic fibroblasts (MEFs) showed telomere shortening

215 compared gene expression in STAT3-null mouse embryonic fibroblasts (MEFs) stably expressing wild-type

216 hibitor to either mouse macrophages or mouse embryonic fibroblasts (MEFs) suppressed IFN-beta and TNF

217 e cells, maintain the DHS landscape of mouse embryonic fibroblasts (MEFs) synergistically.

218 By characterizing the mouse embryonic fibroblasts (MEFs) that express Csn8 at a low

219 ay 18.5 BAT3(-/-) mouse embryos and in mouse embryonic fibroblasts (MEFs) through the modulation of p

220 his transcription factor complex, from mouse embryonic fibroblasts (MEFs) to examine the role of Gabp

221 h1(-/-)p53(-/-) lymphomas and derived murine embryonic fibroblasts (MEFs) were both more sensitive to

222 Mouse embryonic fibroblasts (MEFs) were isolated from Spag6-de

223 tious EBOV derived from SOCS3 knockout mouse embryonic fibroblasts (MEFs) were significantly reduced

224 Hsp70(-/-) murine embryonic fibroblasts (MEFs) were transformed by E1A/Ras

225 ration, and ECM remodeling of primary murine embryonic fibroblasts (MEFs) with cre/loxP-mediated vinc

226 d in Ras(V12)-expressing p19(Arf) null mouse embryonic fibroblasts (MEFs), and overall Egr DNA-bindin

227 e and histone methylation occupancy in mouse embryonic fibroblasts (MEFs), induced pluripotent stem c

228 cells or through genetic knockout in murine embryonic fibroblasts (MEFs), led to significant reducti

229 In mouse embryonic fibroblasts (MEFs), Sirt6 knockout (KO) increa

230 Using knockout mouse embryonic fibroblasts (MEFs), we demonstrate that cyclin

231 ies in Xenopus laevis egg extracts and mouse embryonic fibroblasts (MEFs), we show here that NCOA4 is

232 ng an inducible knockout (KO) model of mouse embryonic fibroblasts (MEFs).

233 nd cell proliferation in Ada3-deleted murine embryonic fibroblasts (MEFs).

234 e in wild-type but not caveolin-1 null mouse embryonic fibroblasts (MEFs).

235 two different cell types, B cells and mouse embryonic fibroblasts (MEFs).

236 transferase PRMT5 controls H4R3me2s in mouse embryonic fibroblasts (MEFs).

237 g a SILAC approach, of PDGF-stimulated mouse embryonic fibroblasts (MEFs).

238 ltransferase for PP2A, PP4, and PP6 in mouse embryonic fibroblasts (MEFs).

239 cell lines, ex vivo tumor tissue, and mouse embryonic fibroblasts (MEFs).

240 n initiation factor 2alpha (eIF2alpha) mouse embryonic fibroblasts (MEFs); moreover, ECD mRNA levels

241 W264.7 cells, primary macrophages, and mouse embryonic fibroblasts [MEFs]) apoptosis induced by a wid

242 In a mouse embryonic fibroblast model, Drp1 C452F cells exhibited a

243 imilarly inhibited nuclear import in a mouse embryonic fibroblast model.

244 e energy transfer; 3) in MPC1 depleted mouse embryonic fibroblasts, MPC1L rescues the loss of pyruvat

245 In transformed but not primary murine embryonic fibroblasts, NLRX1 expression mediated resista

246 Using mouse embryonic fibroblast nuclei with normal or reduced DNA m

247 Murine embryonic fibroblasts null for the UPR-associated transc

248 Embryonic fibroblasts obtained from Stonin1-deficient mi

249 Expressing core in livers or mouse embryonic fibroblasts of ATGL(-/-) mice no longer decrea

250 imicked by inactivation of IR alone in mouse embryonic fibroblasts or in vivo in brown fat in mice.

251 Furthermore, genetic knockout (in murine embryonic fibroblasts) or siRNA knockdown (in BJ fibrobl

252 crophages but not cerebral cortical neurons, embryonic fibroblasts, or dendritic cells sustained high

253 ly, we show that in kindlin-2 knockout mouse embryonic fibroblasts, overactivation of Ras, Akt, and S

254 Plk1 overexpression in mouse embryonic fibroblasts prepared from the transgenic mice

255 SIRT3-null mouse embryonic fibroblasts produced significantly more ROS in

256 lethal in the Chaos3 background and impaired embryonic fibroblast proliferation, suggesting that ATM

257 ption, and decreased ATP production in mouse embryonic fibroblasts, providing insights into the cellu

258 In murine embryonic fibroblasts, (R)-PFI-2 treatment phenocopied t

259 nical autophagy: both WT and Atg5(-/-) mouse embryonic fibroblasts responded similarly.

260 Deletion of USP9X in mouse embryonic fibroblasts resulted in significant downregula

261 However, paradoxically loss of LKB1 in mouse embryonic fibroblast results in resistance to oncogene-i

262 n of Spartan from conditional knockout mouse embryonic fibroblasts results in impaired lesion bypass,

263 , alone or in combination with Trf2 in mouse embryonic fibroblasts results in increased telomere fusi

264 Transcriptome analysis using mouse embryonic fibroblasts revealed deregulation in the trans

265 In vitro investigations with mouse embryonic fibroblasts revealed factors, in addition to N

266 t mutants of vinculin in vinculin-null mouse embryonic fibroblasts revealed that PIP2 binding is nece

267 Furthermore, Fkbp10(-/-) mouse embryonic fibroblasts show retention of procollagen in t

268 Rb1-deficient mouse embryonic fibroblasts showed increased levels of Ogt and

269 of ID8 mouse ovarian tumor cells with mouse embryonic fibroblasts showed that CD73 expression in fib

270 e bone marrow-derived macrophages and murine embryonic fibroblasts stimulated with their cognate grow

271 ng decrease seen in cultured Tsc2(-/-) mouse embryonic fibroblasts, suggesting one mechanism through

272 Toll-like receptor 4 (TLR4) cells and murine embryonic fibroblasts than wild-type LOS of the parent s

273 s are abrogated in lamin A/C-deficient mouse embryonic fibroblasts that recapitulate the defective nu

274 s Ucp1 expression in undifferentiated murine embryonic fibroblasts, that this induction depends on ME

275 In contrast, in mouse embryonic fibroblasts the coding segment is depleted of

276 responses of embryonic stem cells and mouse embryonic fibroblasts to amber codon suppression.

277 We demonstrate that adaptation of mouse embryonic fibroblasts to cell culture results in a rapid

278 d Myt1l genes (BAM factors) to convert mouse embryonic fibroblasts to induced neuronal cells.

279 s to dissect direct reprogramming from mouse embryonic fibroblasts to induced neuronal cells.

280 the reprogramming routes leading from mouse embryonic fibroblasts to induced pluripotency.

281 ulting knock-out animals, we also used mouse embryonic fibroblasts to investigate the associated sign

282 Gamitrinib strongly sensitizes primary mouse embryonic fibroblasts to mPT and permeability transition

283 eratinocytes, human keratinocytes, and mouse embryonic fibroblasts to TNF-induced apoptosis.

284 Here, we take advantage of mouse embryonic fibroblasts transformed by oncogenic Dbl, whic

285 mor cell lines, mouse lung tumors, and mouse embryonic fibroblasts undergoing RAS-induced senescence.

286 ion of iNOS decreases cell survival in mouse embryonic fibroblasts via mechanisms involving nitric ox

287 says with Top1mt* in Top1mt knock-out murine embryonic fibroblasts, we demonstrate that Top1mt* forms

288 In wild type and FAK knock-out mouse embryonic fibroblasts, we found by immunoblotting, immun

289 For endogenous beta-actin genes in mouse embryonic fibroblasts, we observe that short-lived (~8 s

290 Mitochondria in C452F mouse embryonic fibroblasts were depolarized and had reduced c

291 ated in aging, blocked iN cell conversion of embryonic fibroblasts, whereas knockout or knockdown of

292 d recycling of alpha5beta1-integrin in mouse embryonic fibroblasts, which enables persistent fibrobla

293 e examined the Hh signaling pathway in mouse embryonic fibroblasts, which readily responds to the Hh

294 The use of Ada3(FL/FL) mouse embryonic fibroblasts with deletion of Ada3 using adenov

295 Mouse embryonic fibroblasts with genetic ablations of TSC2 or

296 Mouse embryonic fibroblasts with Ptpn11 GOF mutations show a c

297 We used primary Ercc1 (-/-) murine embryonic fibroblasts with reduced DNA repair capacity,

298 tol (3,4,5)-trisphosphate (PIP3), from mouse embryonic fibroblasts with serum stimulation.

299 Finally, we treated Mecp2(R255X) embryonic fibroblasts with the nonsense mutation suppres

300 ranslocation was observed in wild-type mouse embryonic fibroblasts (WT MEFs), Tg2576 MEFs, and N2a ne