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1 ip is critical to limit multidrug resistance emergence.
2 ility to pathogens and contribute to disease emergence.
3 it from proteolytic digestion, and guide its emergence.
4 ntral to understanding the nature of disease emergence.
11 beta-lactam antibiotics is threatened by the emergence and global spread of metallo-beta-lactamase (M
12 e formation as a paradigm to investigate the emergence and integration of novel complex structures fo
14 or dynamics primarily by reducing new branch emergence and leads to impoverished terminal arbors.
15 y bias as one key factor contributing to the emergence and maintenance of social anxiety disorder (SA
16 ng, are likely to play a greater role in the emergence and maintenance of supernatural belief than co
18 31 identified differences in the dynamics of emergence and showed that expansion of ST131 in this pop
25 at conformational flexibility can assist the emergence and subsequent evolution of new active sites b
36 eology of human immunodeficiency virus (HIV) emergence following human exposures to simian immunodefi
37 eurological disease is consistent with their emergence from a viral population already established th
39 iation of body mass index (BMI) with FPM/SPM emergence in a representative sample of US children and
40 characterize the genetic features of bla KPC emergence in global E. coli, 2008-2013, using both long-
42 istory of Zika virus began in 2007, with its emergence in Yap Island in the western Pacific, followed
43 roups [1-8], but it is unclear whether their emergence is determined by their social influence versus
45 cells, rather than the sites of lateral root emergence, mediates the transport of apoplastic substanc
46 Cooperative behaviours can be damaged by the emergence of 'cheating' cells that benefit from the coop
47 ng of translational symmetry in time and the emergence of a 'time crystal' was recently proposed, but
49 e of those with impaired vision, we found an emergence of a contribution of sociodemographic status t
50 scaling of icebergs can be explained by the emergence of a dominant set of driving processes of iceb
51 Altogether, our work unveils the convergent emergence of a Drosophila-like dosage compensation mecha
54 easing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in thi
55 comparative and genomic analyses reveal the emergence of a new group or cluster of viruses encompass
56 et development of nanomaterials, such as the emergence of a new widely used product or the ban on cer
58 orless prions into wild type mice led to the emergence of a novel strain with a unique biochemical an
59 )N/(14)N record and provide evidence for the emergence of a pervasive aerobic marine nitrogen cycle.
60 We find a clear correspondence between the emergence of a phase transition, and the emergence of at
61 ution (time delay between photon arrival and emergence of a QB), and (iv) refractory period distribut
63 In a new study, Grossman et al. leverage the emergence of a slowly oscillating "beat" from intersecti
65 5(+)lin(-)CD25(+) cells) and IL-13(+) ILC2s, emergence of a TSLP receptor-positive IL-9(+) ILC2 popul
66 ise either to molecular diversity, i.e., the emergence of a unprecedentedly large range of macrocycle
69 with standard cytotoxic therapies prevented emergence of acquired resistance and augmented chemother
70 lexes and neonatal Fc receptor (FcRn) in the emergence of ADAs in the case of anti-TNF-alpha Abs.
73 ly, a dominant mechanism associated with the emergence of an anergic and regulatory CTLA-4(+)IL-2(low
75 cytotoxicity of NK cells but also led to the emergence of an immature NK cell population that express
76 in theoretical analyses, contributes to the emergence of an important computational function through
78 urinary tract infections has resulted in the emergence of antimicrobial resistance, necessitating alt
79 the prefrontal systems may contribute to the emergence of anxiety and depressive symptoms and may pla
84 the emergence of a phase transition, and the emergence of attractor-like structure in the inferred en
88 Recent longitudinal studies have traced the emergence of bNAbs in HIV-1 infection, inspiring novel a
91 innate cortical mechanism contributes to the emergence of broad orientation selectivity in PV interne
92 y low cannibalistic tendencies, and that the emergence of cannibalism-avoidance behaviour depends str
93 nd carbapenem overuse has contributed to the emergence of carbapenem-resistant Enterobacteriaceae.
95 ata on the use of ceftolozane-tazobactam and emergence of ceftolozane-tazobactam resistance during mu
99 nt might change in the near future, with the emergence of clinically useful tyrosine kinase inhibitor
101 esidues 393-396, may have contributed to the emergence of cluster IIIb strains and the persistence of
104 al variation in space-use, demonstrating the emergence of complex population-level patterns from diff
113 ith time, monolayers jam, accompanied by the emergence of deformation waves that propagate away from
116 nearly simultaneous, and recent, independent emergence of different clonal populations on 3 continent
117 rable to these earliest ones, but show clear emergence of diverse traits, including increased cob wid
118 tinct volcanoes, explaining the simultaneous emergence of double-track volcanism across the Pacific;
121 scuss phylogenetic methods used to study the emergence of drug resistance and the spread of resistant
123 minor variants, which could give rise to the emergence of drug resistance in cases of drug pressure w
131 ination therapies is critical to address the emergence of drug-resistant cancers, but direct screenin
132 gene-targeted therapy ultimately enables the emergence of drug-resistant clones, limiting the long-te
133 iral infections and cancer often lead to the emergence of dysfunctional or 'exhausted' CD8(+) T cells
134 The functional threshold is lower for the emergence of early symptoms before the classical motor s
135 o shed light on the processes underlying the emergence of electromotility, we focused on the betaV gi
137 to the DNA-based viruses in prokaryotes, the emergence of eukaryotes provided the necessary compartme
138 chain to photosystem I, directly led to the emergence of eukaryotic and multicellular organisms.
139 m such a simple scheme demonstrates that the emergence of exponentially growing metabolisms could be
140 n of the ancestral structure and enables the emergence of extensively different cyclic peptides throu
141 ce in situ hybridization analyses mapped the emergence of extra-chromosomal amplification in parallel
142 entially at faces, even at ages prior to the emergence of face domains, but face-deprived monkeys did
143 ant implications for understanding the rapid emergence of fine-grained, high-level representations of
147 oietic stem and progenitor compartments with emergence of functional mIDH2 neutrophils were observed.
149 e proposed mechanism accounts for the graded emergence of gamma oscillations at the stimulation site
150 brain function, which in turn moderates the emergence of general liability as individual risk for me
151 uding its classically recognized role in the emergence of genetically "shifted" pandemic strains as w
152 ts to later communicative functions, and the emergence of gesture and/or sign as potential communicat
153 s provide an image-based explanation for the emergence of higher-level representations in scene-selec
155 sion events among felids that compare to the emergence of HIV from nonhuman primates.IMPORTANCE Cross
156 ost transition could interact to promote the emergence of host generalist lineages of the zoonotic ba
166 tomic changes are present in DCIS before the emergence of invasive disease, indicating that the malig
169 n non-invasively in real time has led to the emergence of its applications in areas that are relevant
171 extinction of oncogenic Kras signalling and emergence of Kras-independent escaper populations (cells
172 anual modality, this offers insight into the emergence of language in ways that the oral modality can
175 rom-equilibrium thermodynamics underpins the emergence of life, but how has been a long-outstanding p
176 y of self-assembly strategies leading to the emergence of lipid bicontinuous single crystals with unp
181 ce traits is central for the emergence or re-emergence of microbial pathogens and for their adaptatio
182 ledge of polymorphisms that occur before the emergence of multidrug resistance, particularly katG p.S
183 Here, we introduce a novel mechanism for emergence of multiple band gaps with extreme attenuation
186 seen in human retinoblastoma and reveals the emergence of MYCN independence in an initially MYCN-driv
188 iversification of hosts, including the rapid emergence of new enterococcal species following the End
192 curvature and hydrophobic forces lead to the emergence of new protein functional states within the me
193 from flooding, shifting fish stocks and the emergence of new shipping opportunities in the Arctic, w
194 ions from first principles and addresses the emergence of new states of matter in chemistry and mater
195 ith the continuous evolution of diseases and emergence of new strains, yet prediction of unknown clas
196 lacement, reduce transmission, and limit the emergence of new variants, it is essential to induce bro
199 in LRRK2 Parkinson's disease, including the emergence of non-motor symptoms and, potentially, differ
200 by loss of dominance of frontal regions and emergence of nonfrontal regions, correlating to our beha
201 novel developments in SI-CRP, as well as the emergence of novel applications such as catalysis, elect
203 are especially useful for studying the early emergence of novel pathogens given the importance of cha
207 increase in antimicrobial resistance and the emergence of other MDR pathogens, such as malaria, HIV,
208 cators and the effects of replicators on the emergence of other replicators remains under-investigate
209 theast Asian countries have now reported the emergence of parasites that have decreased susceptibilit
213 simple model to mechanistically explain the emergence of periodic changes in length and spatiotempor
214 study provides mechanistic insights into the emergence of plant chemical novelty, and offers a templa
217 evolutionary mechanisms that both enable the emergence of polyphagous herbivory and lead to the shift
218 chiral anomaly of Weyl fermions-namely, the emergence of positive magnetoconductance only in the pre
219 etroviral therapy in that it facilitates the emergence of potent CD8(+) T-cell immunity able to durab
222 Bose-Einstein condensates is enriched by the emergence of quantum correlations whose description dema
224 d data processing algorithms have led to the emergence of Ramanomics - an independent discipline with
225 Our directly comparable estimates of the emergence of reactivity for 20 immunoassays are valuable
227 phylogeography approach to characterize the emergence of recombinants in Brazil and Haiti and report
228 astomas are primary resistance and the rapid emergence of recurrent disease, which can result from tu
229 logical studies have been able to detect the emergence of regional clonal and nonclonal resistance in
231 uch therapies may be less susceptible to the emergence of resistance than traditional antibiotics.
232 ing of the antibiotic pipeline and the rapid emergence of resistance to approved antibiotics, this gr
233 es of antifungal drugs are available, so the emergence of resistance to single drug classes and now m
234 following vemurafenib treatment enables the emergence of resistance, with potential implications for
237 ytotoxic T cell (CTL) in vivo results in the emergence of resistant cancer cell clones only in the pr
238 have substantial short-term effects, but the emergence of resistant cancer cells is a major barrier t
241 The complex evolutionary pathway for the emergence of resistant viruses, which includes the need
247 uggest that live bearing has facilitated the emergence of social groups that remain stable across yea
249 in mouse and human glioma and found that the emergence of specific subpopulations during tumor progre
251 the most successful lineages identified the emergence of ST131 and ST69 and their establishment as t
257 adaptive genetic repertoire that allowed the emergence of taxon-specific complex social behaviors, su
259 ork was implemented to estimate the relative emergence of test reactivity, referred to here as an int
261 and acceptors to set up alliances makes the emergence of the first harder whenever the latter are pr
262 he agricultural economy that underpinned the emergence of the first urban centres in northern Mesopot
266 lar distribution of influx carriers; (2) the emergence of the same auxin pattern, from different leve
271 racteristics of recombination events and the emergence of this previously neglected virus in Haiti, a
281 existing classes of antibiotics and with the emergence of vancomycin-resistant pathogens (VRSA and VR
282 entire A1/D1 East cluster caused the sudden emergence of Verticillium stem striping in the UK, where
284 may still occur, potentially leading to the emergence of viral resistance, which can decrease the ef
286 These data shed important insights on the emergence of viruses within an important trypanosomatid
291 infection are infectious it could explain re-emergences of Ebola virus disease (EVD) without known co
293 l diversity was in no case paralleled by the emergence or expansion of X4-tropic provirus variants.
294 ution of virulence traits is central for the emergence or re-emergence of microbial pathogens and for
296 Resource limitation prevented resistance emergence regardless of whether resistant mutants arose
298 biopolymer dynamics reveal pathways for the emergence, self-selection and amplification of chain-len
299 l transmission from the source, (ii) de novo emergence shortly after infection followed by viral sele
300 l serogroup W with meningococcal serogroup C emergence, the rapid expansion of the MenW:cc11 2013 str
301 is a significant risk factor for de novo DSA emergence, whereas the persistence of antibodies is pred
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