ライフサイエンスコーパス: emergent

1 ite adipose tissue (iWAT), a common site for emergent active iBAT.

2 nity to use thermodynamic theory to study an emergent adaptive animal behaviour.

3 mortality in patients with both elective and emergent admissions.

4 At least one emergent adverse event (AE) was recorded for 79/190 (41x

5 in the placebo group had a severe treatment-emergent adverse event (insomnia).

6 e safety analysis had at least one treatment-emergent adverse event deemed to be related to study tre

7 The most common grade 3 or 4 treatment-emergent adverse event in each treatment group was neutr

8 ciated with an increase in overall treatment-emergent adverse event rates or neurocognitive events, a

9 treatment, and therefore was not a treatment-emergent adverse event).

10 d Nexvax2 150 mug had at least one treatment-emergent adverse event, as did all three (100%) placebo

11 d Nexvax2 300 mug had at least one treatment-emergent adverse event, as did six (86%) of seven placeb

12 ortion of patients who experienced treatment-emergent adverse events (79% [1125 of 1432 patients] for

13 Treatment-emergent adverse events (eg, insomnia, akathisia, worsen

14 essant reported significantly more treatment-emergent adverse events (RR, 1.07; 95% CI, 1.01-1.12; P

15 In both studies, treatment-emergent adverse events (TEAEs) reported by 10% of LDX p

16 ge of responders by age strata and treatment-emergent adverse events (TEAEs).

17 The most common grade 3-4 treatment-emergent adverse events across all doses were increased

18 gic reactions and no difference in treatment-emergent adverse events between the groups (64 [99%] of

19 Proportions of patients with treatment-emergent adverse events by system organ class were simil

20 Incidence of treatment-emergent adverse events did not differ between extended-

21 The most common treatment-emergent adverse events in all 32 patients were nausea (

22 e XR-NTX injection site reactions, treatment-emergent adverse events including overdose did not diffe

23 Treatment-emergent adverse events leading to death occurred in 23

24 The treatment-emergent adverse events observed were generally consiste

25 en the MTD, eight gastrointestinal treatment-emergent adverse events occurred in four (50%) of eight

26 Treatment-emergent adverse events of grade 3 or higher in the safe

27 Treatment-emergent adverse events of grade 3 or worse occurred in

28 %) and 69 (16%), respectively, had treatment-emergent adverse events that led to withdrawal.

29 nausea, and headache were the only treatment-emergent adverse events that occurred in at least 5% of

30 n the CT-P6 group reported serious treatment-emergent adverse events versus 22 (8%) of 278 in the ref

31 Rates of grade 3 or 4 treatment-emergent adverse events were 41.2%, 60.1%, and 46.0% for

32 The most common grade 3 or worse treatment-emergent adverse events were anaemia or decreased haemog

33 The most common treatment-emergent adverse events were diarrhoea in the pitavastat

34 did not differ between groups, and treatment-emergent adverse events were evenly distributed.

35 generally well tolerated and most treatment-emergent adverse events were mild to moderate in severit

36 Most treatment-emergent adverse events were mild to moderate in severit

37 Treatment-emergent adverse events were reported by 55 (85%) of 65

38 Treatment-emergent adverse events were reported for 58 (83%) of 70

39 Treatment-emergent adverse events were reported in 103 patients (9

40 Treatment-emergent adverse events were reported in 328 (74%) patie

41 Moderate treatment-emergent adverse events were reported in two patients in

42 The most common treatment-emergent adverse events were somnolence (10.0%), akathis

43 aking carbamazepine-CR had serious treatment-emergent adverse events, and 47 (11%) and 69 (16%), resp

44 For our analysis, rates of SVR12, treatment-emergent adverse events, and graded laboratory abnormali

45 ed with pravastatin (70%) reported treatment-emergent adverse events, and these caused study disconti

46 The most frequently reported treatment-emergent adverse events, regardless of causality, in eit

47 erated; 82 (77%) patients reported treatment-emergent adverse events, which were mostly minor.

48 Safety assessments included treatment-emergent adverse events.

49 nt serious adverse events, and all treatment-emergent adverse events.

50 ith few significant differences in treatment-emergent adverse events.

51 rade 3 or 4) being the most common treatment-emergent adverse events.

52 clinical management group reported treatment-emergent adverse events; no treatment-related deaths occ

53 y outcome of the TAUSSIG study was treatment-emergent adverse events; secondary outcomes were the eff

54 Treatment-emergent AEs included hypertension (two of eight), diarr

55 therapy compared with placebo for treatment-emergent all-cause mortality (p=0.0420), idiopathic-pulm

56 0.52 [95% CI 0.31-0.87; p=0.0107]; treatment-emergent all-cause mortality 0.45 [0.24-0.83; 0.0094]; i

57 52 weeks)-for all-cause mortality, treatment-emergent all-cause mortality, idiopathic-pulmonary-fibro

58 s, and expansion of the RGI for detection of emergent AMR threats.

59 s were recorded, of which 117 were treatment emergent and included six classified as severe, but no s

60 materials with active, adaptive, autonomous, emergent and intelligent behavior.

61 the secondary endpoints of safety (treatment-emergent and treatment-related adverse events according

62 This emergent approach to health conception and clinical prac

63 The emergent bandgap is bestowed with lifelike properties, s

64 lso offers new insight for understanding the emergent behavior of sophisticated molecular systems hav

65 We developed an approach to examine emergent behaviors that couples fluorescent cell trackin

66 and regulation of Rubisco activity leads to emergent behaviors that may affect the operation and reg

67 n both new scientific phenomena, such as the emergent behaviour at oxide interfaces, and key technolo

68 ch in relating the expression of complex and emergent behaviour in networks of replicators with the c

69 tics including hierarchical organisation and emergent behaviour.

70 This emergent bias was mirrored by the innervation pattern of

71 roteins gain and lose mRNAs with related and emergent biological functions during evolution.

72 We propose that emergent biophysical properties associated with phase-se

73 These data suggest a new model by which emergent brain function and behavior result from cortica

74 teristic Bragg reflections at the edge of an emergent Brillouin zone.

75 eurons, called neuronal ensembles, which are emergent building blocks of neural circuits.

76 while an organometallic trap intercepts the emergent carbanion.

77 ychiatric illness, neutropenia, or requiring emergent care, we attempted to collect rectal swabs and

78 This emergent CD41(Hi) HSC fraction demonstrates no observabl

79 marks (epi-marks) in stem cells to classify emergent cell states.

80 simulations to show that shape sensing is an emergent cellular property enabled by multiple molecular

81 ut quantitatively linking these changes with emergent cellular scale functionality.

82 Our simulations demonstrate that this emergent chiral behaviour is driven by the topology of t

83 and, by doing so, probe cell-autonomous and emergent, circuit-level properties.

84 se missed by conventional BLAST searches, an emergent clade of tombus-like viruses, and an example of

85 re was compared to the phylogenetics of RSV, emergent clades were identified that we termed High Titr

86 Amphidynamic crystals are an emergent class of condensed phase matter designed with a

87 Preference correlated with three emergent co-culture properties: ethanol catabolism, a di

88 phenomena, because we were interested in the emergent cognitive capacities that would pop out of a ne

89 re discharged to a nonhome destination after emergent colectomy.

90 gulating cell division is crucial for tuning emergent collective migratory behaviors, such as vortica

91 Emergent communities from simulations that were initiali

92 ole of flexoelectricity in the generation of emergent complex polarization morphologies and demonstra

93 embly code.SIGNIFICANCE STATEMENT We analyze emergent computational properties of a ubiquitous cortic

94 tion of cortical microcircuits is to analyze emergent computational properties of these stereotypical

95 nged dwell time and catheter insertion under emergent conditions increased risk of PVC-related bloods

96 ts on properties, resulting, for example, in emergent conduction behaviour, large changes in metal-in

97 captured little formal information about the emergent connections between parameters that define the

98 is proposed to perform determinations of the emergent contaminant perchlorate in vegetable matrices d

99 ll as avoiding canopy gaps and moving toward emergent crowns.

100 Emergent data from cultivation and next-generation seque

101 t lymphopenia is one hallmark of sepsis, and emergent data indicate the CD4 T cell compartment in sep

102 24-72 hours of exposure--and 30-day post-CT emergent dialysis and death were determined after propen

103 Rates of AKI, emergent dialysis, and mortality were compared between I

104 pare the rates of acute kidney injury (AKI), emergent dialysis, and short-term mortality between pati

105 erences in the predicted outbreak size of an emergent disease.

106 ncluded evaluation of baseline and treatment-emergent drug resistance.

107 us that northern Shatsky Rise was remarkably emergent during its final emplacement phase.

108 hat number sense is not innate but gradually emergent during ontogeny following experience.

109 signalling cascades, and discuss some of the emergent dynamic behaviour found in hallmark examples.

110 has emerged as a novel model used to explore emergent dynamics.

111 Results also imply that emergent ecological dynamics of individual fitness reduc

112 Thus far, data-based evaluations of emergent ecosystem responses to climate and CO2 at multi

113 ger-term consequences for pair formation and emergent effects determined by social structure such as

114 rvation and restoration actions that use the emergent effects of self-organization to increase ecosys

115 tions involving two spin sublattices and the emergent effects they may drive.

116 icted to generate a new quantum basis for an emergent electron gas that supports diffusive electrical

117 itically important material for the study of emergent electronic phases in complex oxides, as well as

118 lated matter, but also to search for unusual emergent electronic phases.

119 The emergent electronic structure picture reveals that Cu co

120 Treatment-emergent events leading to death occurred in 36 (9%) of

121 n clinically relevant grade 3 or 4 treatment-emergent events were hypertension (57 patients [15%] in

122 Serious treatment-emergent events were noted in 22 (19%) patients in treat

123 This emergent fast timescale for signaling is reflected in ga

124 nent role of biomechanics in determining the emergent features of amoeboid locomotion.

125 Moreover, triply-degenerate nodes realize emergent fermionic quasiparticles not present in relativ

126 ch to investigate multifactorial cell-stress emergent from diverse bioinstrumentation, which can be u

127 sequence alone based on sequence signatures emergent from TERM instances in the PDB.

128 structures and bring forward the prospect of emergent functionalities due to topological transitions.

129 tromagnetic properties of oxides and related emergent functionalities that have implications for devi

130 h which to create ordered metamaterials with emergent functionalities.

131 Here, we review the emergent functions of RNA exosome during CSR, SHM, and o

132 described as Coulomb phases, governed by an emergent gauge principle.

133 l complexes we investigate the nature of the emergent geometry of complex networks and explore whethe

134 In total, 1240 patients undergoing emergent GI surgery while treated with clopidogrel were

135 6 to 2011, we identified patients undergoing emergent GI surgery.

136 The most common treatment-emergent grade 3 or 4 adverse events were neutropenia (4

137 multimodal individual behavior jointly with emergent group behavior is readily extensible to additio

138 ce, backed by theory, that this motion is an emergent group effect that does not require any behavior

139 ework, where selection for cooperation among emergent groups can overcome selection against cooperato

140 Seventeen (55%) patients developed treatment-emergent GVHD after initiation of anti-PD-1 (6 acute, 4

141 Treatment-emergent hepatotoxicities (of all grades) were more freq

142 is describes investigator-assessed treatment-emergent hepatotoxicity, including sinusoidal obstructio

143 structures, and how these topologies lead to emergent, high-level GRN functions.

144 is-related mortality (0.0237), and treatment-emergent idiopathic-pulmonary-fibrosis-related (0.0132)

145 ry-fibrosis-related mortality, and treatment-emergent idiopathic-pulmonary-fibrosis-related mortality

146 ortality 0.35 [0.17-0.72; 0.0029]; treatment-emergent idiopathic-pulmonary-fibrosis-related mortality

147 e efficient dual vaccines against rabies and emergent infectious diseases such as Ebola virus.

148 An emergent insight from these studies is that endocannabin

149 Thus, the frequency optima arise from emergent interactions of transport across the membrane s

150 ic order in Cr-doped (Bi,Sb)2Te3, we realize emergent interfacial magnetic phenomena which can be tai

151 Patients requiring emergent intubation prior to endovascular therapy were e

152 event, and 12 (100%) patients had treatment-emergent lab abnormalities.

153 CT findings and emergent laparotomy findings were both compatible with s

154 delivery of care for patients with suspected emergent large-vessel occlusion (ELVO), efficient system

155 ncluding all known Lp serogroups 1-17 and 17 emergent LD-causing Legionella species (of which 33 were

156 e drl genes are coexpressed in incipient and emergent leaf primordia at the shoot apex, but not in th

157 ocesses of acquisition, capable of capturing emergent lexicon structure.

158 by a first-order phase transition between an emergent, low-temperature vortex phase with electric tor

159 ial and may open a window into investigating emergent magnetic Majorana fermions in correlated materi

160 to specific collective behaviour, including emergent magnetic monopoles, charge screening and transp

161 cells differentially communicate to support emergent malignancy.

162 iation between methylphenidate and treatment-emergent mania among patients with bipolar disorder who

163 rs sought to determine the risk of treatment-emergent mania associated with methylphenidate, used in

164 indings enable developing a platform for the emergent many-valued non-Boolean information technology

165 uxes of CO2 , CH4 , and N2 O from a restored emergent marsh ecosystem.

166 n the theoretical studies and fabrication of emergent materials and their structures.

167 acilitate the realization and integration of emergent mechanisms underlying its three major functions

168 Emergent medical care was associated with survival in pa

169 We conclude that the emergent memory effect originates from phase boundaries

170 Our results support a model whereby emergent metabolites signal a beneficial multispecies mi

171 ct relevant experimental conditions for this emergent methodology.

172 nem-resistant Enterobacteriaceae (CRE) is an emergent microorganism of infections after liver transpl

173 Formal evaluation of emergent model behavior at multidecadal and multicentenn

174 Although it is rapidly becoming an emergent model for environmental and population genomics

175 This emergent model supports the concept of SCZ as an 'associ

176 ynamic ECM is required for generation of the emergent motion patterns that drive amniote morphogenesi

177 Utilizing emergent motor platforms for in vivo applications is one

178 ectivity, traits of individuals that explain emergent movement patterns, and sites that play a critic

179 nly prove that in operando methods can yield emergent nanomaterials, which in turn deliver exceptiona

180 qualized, an outcome we term "evolutionarily emergent near-neutrality." For different environmental c

181 Awareness and knowledge of emergent ophthalmic disease may be important for early m

182 Levels of awareness and knowledge of emergent ophthalmic diseases are low.

183 ments and structural coloration often yields emergent optical properties.

184 ng its legalization in some countries, poses emergent oral and periodontal health concerns.

185 ompetition, order parameter coexistence, and emergent order parameter topologies constitute a major p

186 e layered Ising magnet Dy3Mg2Sb3O14 hosts an emergent order predicted theoretically for individual ka

187 Nipah virus is an emergent paramyxovirus that causes deadly encephalitis a

188 Mathematical models of emergent pathogens allow forecasts of case numbers, inve

189 To rationalize this emergent pattern of cell sizes, we propose a tractable m

190 Emergent patterns of diversity include predictable varia

191 rmittent HMI impulses (n = 20) just prior to emergent percutaneous coronary intervention (PCI) and fo

192 Of the patients who experienced treatment-emergent peripheral neuropathy, 88% experienced either r

193 between the degree of crystallinity and the emergent perovskite/hole (or electron) transport layer o

194 Herein, we discuss the most emergent perspectives on the relationship between KRAS-m

195 required to control both phage-sensitive and emergent phage-resistant variants to clear infection.

196 A variety of emergent phenomena have been enabled by interface engine

197 The discovery of emergent phenomena in 2D materials has sparked substanti

198 The non-equilibrium control of emergent phenomena in solids is an important research fr

199 synergy, sometimes leading to higher-order, emergent phenomena.

200 Many dynamic systems display complex emergent phenomena.

201 rformance of a motor task, the network shows emergent phenomena: it functions as a selection mechanis

202 It is proposed here that cancer is also an emergent phenotype that supervenes upon heterocellular s

203 This emergent phenotype was observed only when the available

204 In addition, it enables tuning of the emergent physical properties of complex oxides, through

205 ario in the diffusive limit, we consider the emergent physics in hybrid structures comprised of a con

206 peak growing season for the dominant aquatic emergent plants in the Alaskan arctic coastal plain, Car

207 An emergent population of peripheral CD4 T cells conferred

208 Thirty-nine patients were excluded owing to emergent pre-endovascular therapy intubation.

209 the plausibility of the results and provides emergent predictions that are consistent with our empiri

210 new strategies and approaches to solve this emergent problem?

211 r symmetries are simultaneously broken by an emergent process of cellular self-organization.

212 The impacts of changing climate regimes on emergent processes controlling the assembly of ecologica

213 eneric sociological theory that explains how emergent projects of collective action are progressed in

214 Aligned graphene flakes exhibit emergent properties approaching single-layer graphene.

215 lti-component mixture can be used to uncover emergent properties arising from polypharmacological act

216 Theoretical studies suggest that many of the emergent properties associated with multicellular system

217 ides, and provides a pathway for engineering emergent properties in quantum matter.

218 a pivotal role for the determination of the emergent properties of a system.

219 t functional coordination across species and emergent properties of ecosystems, and a potential basis

220 ctromagnetic radiation, can give rise to the emergent properties of in-phase, out-of-phase, anti-phas

221 ve functions such as working memory (WM) are emergent properties of large-scale network interactions.

222 These results reveal newly emergent properties of macroscopic cortical dynamics dur

223 Collective cell movement is critical to the emergent properties of many multicellular systems, inclu

224 imaging tool will allow for the study of the emergent properties of neural circuits and permit experi

225 To understand the emergent properties of neural circuits, it would be idea

226 The emergent properties of the Auditory Cortex (ACx) have be

227 Instead, they are emergent properties of the cell community which forms a

228 le to its internal microstructure and to the emergent properties of the self-assembled materials, the

229 t predatory taxa in many ecosystems, and the emergent properties of their joint effects on insect her

230 Predicting emergent properties represents a huge theoretical proble

231 lonized by pathobiota dynamically expressing emergent properties which drive, and are driven by, a pa

232 ructure is essential for understanding their emergent properties, but has remained enigmatic.

233 i larger than 10 microns, exhibiting several emergent properties, including periodic growth and colla

234 These multi-scale patterns and other emergent properties, such as enhanced resistance to and

235 s, and promises to create a diverse range of emergent properties.

236 ng robust, sustainable states with favorable emergent properties.

237 zation that inhibits the robustness of these emergent properties.

238 to develop complex molecular systems showing emergent properties; i.e. properties that go beyond the

239 operates as an antagonistic network with the emergent property of bistability are discussed.

240 tterns of individual foraging related to the emergent property of residential movements.

241 his suggests that the adder phenomenon is an emergent property of the independent regulation of pre-

242 cyclic pattern of glycogen accumulation, an emergent property of the model, has timing characteristi

243 f trophic control in complex food webs is an emergent property of the system and thus unintuitive.

244 etric growth of cells within the network, an emergent property of this system and a feature commonly

245 y as a selection mechanism also occurs as an emergent property, and closer fits to the data gave bett

246 sents one of the best-understood examples of emergent protein self-organization in nature.

247 monopoles become long range entangled and an emergent quantum electrodynamics arises, seems within re

248 plant tissues, and that cell size may be an emergent rather than directly determined property of cel

249 In this study, we utilize an emergent relation between the land surface and atmospher

250 No treatment-emergent resistance mutations occurred in those who fail

251 No treatment-emergent resistance to any study drug was observed.

252 No individual developed treatment-emergent resistance to any study drug.

253 There was no emergent resistance to either regimen.

254 y for all groups, and baseline and treatment-emergent resistance-associated substitutions (RASs).

255 abacavir, and lamivudine, with no treatment-emergent resistance.

256 Emergent responses of the immune system result from the

257 is known about the antidepressant treatment-emergent risk of type 2 diabetes among youths.

258 There were no 30-day treatment-emergent SAEs.

259 hows that the jamming transition exhibits an emergent scale invariance, setting the stage for the pot

260 Emergent self-induced interface currents promote active

261 ients who experienced at least one treatment-emergent serious adverse event was 16 (23%) of 70 patien

262 the soft-tissue sarcoma group) had treatment-emergent serious adverse events (SAEs), five of whom had

263 There were no treatment-emergent serious adverse events at 30 days or treatment-

264 Treatment-emergent serious adverse events occurred in 103 (7%) wom

265 11 treatment-emergent serious adverse events were noted in seven pati

266 AUClast) of tenofovir alafenamide, treatment-emergent serious adverse events, and all treatment-emerg

267 ctions in elderly patients are often done in emergent settings.

268 e and the presence and severity of treatment-emergent side effects.

269 osed of variably-spaced half-sites (12%) or 'emergent' sites (16%) that cannot be readily inferred fr

270 occur in the primordial germ cells (PGCs) of emergent starved L1 larvae that correlate with compromis

271 taev quantum spin liquid (KQSL) is an exotic emergent state of matter exhibiting Majorana fermion and

272 Nonequilibrium emergent states evolve with a complex co-existence of ex

273 nary disease (5% versus 3%, P=0.004), urgent/emergent status (6% versus 4%, P=0.01), and worse New Yo

274 which hospital performance is correlated on emergent STEMI and AIS care is unknown.

275 del that uses local processes to capture the emergent structural properties of correlation networks w

276 apshot analyses of the initial design or the emergent structure of polycentric regimes.

277 association between habitat features and the emergent structure of the group, highlighting the import

278 n exhibit persistent time correlations at an emergent subharmonic frequency.

279 uenza hemagglutinin (HA) from H1N1 and newly emergent subtypes such as H5N1 and H7N9.

280 uce broad, cross protective immunity against emergent subtypes.

281 GRIA3 and GRIK2 (which likely play a role in emergent suicidal ideation after antidepressant treatmen

282 n rhinoceros, as less suitable habitat on an emergent Sundaland corridor isolated Sumatran rhinoceros

283 ance of hosts as selective agents that shape emergent symbiont populations.

284 These emergent synergies, and the core hubs of interaction tha

285 g how collective myosin interactions produce emergent system behavior.

286 hest-risk PE, presenting as shock or arrest, emergent systemic thrombolysis or embolectomy is reasona

287 interact and reinforce each other, producing emergent systems that are more robust.

288 y components of layered heterostructures for emergent technologies beyond conventional optoelectronic

289 were transcribed, iteratively analyzed, and emergent themes identified.

290 The purpose of this paper is to describe emergent themes that offer new insight describing the re

291 ase modification, and here report on several emergent themes: (1) Fungal endophyte effects on plant d

292 Such emergent tissue-level phenotypes can be said to 'superve

293 ofluidic junctions, which then interact with emergent topological defects in the orientational field

294 tronic properties, making it a cornucopia of emergent topological fermions.

295 oretically predicted to possess a variety of emergent topological properties, experimental verificati

296 s issued into an obstructed cross-flow, with emergent vegetation simulated with a regular array of cy

297 ephra layers were derived from subglacial to emergent volcanism that erupted through the WAIS.

298 age, 75 [range, 24-94] years), 81 (73%) were emergent vs 30 (27%) elective admissions.

299 ly 75% of this carbon was found in estuarine emergent wetlands with freshwater tidal wetlands holding

300 iled SCP networks for predictive modeling of emergent whole cell functions.