ライフサイエンスコーパス: emigrant

1 spaces and reduced numbers of recent thymic emigrants.

2 but positively correlated with recent thymic emigrants.

3 the CD25(-) subset and are not recent thymic emigrants.

4 transferred mature T cells and recent thymic emigrants.

5 + regulatory T cells among the recent thymic emigrants.

6 nerated through the production of new thymic emigrants.

7 ion of truly naive T cells and recent thymic emigrants.

8 rast, thymectomy eliminated LN recent thymic emigrants.

9 nly after the removal of CD25- recent thymic emigrants.

10 flects the phenotype of recent normal thymic emigrants.

11 are phenotypically described as naive thymic emigrants.

12 ls, including CD31(+)/CD4(+) putative thymic emigrants.

13 de novo responses derived from later thymic emigrants.

14 owed the highest percentage of recent thymic emigrants.

15 ary sources to estimate rates of death among emigrants.

16 CD45RA CD31, suggesting they were new thymic emigrants.

17 also observed in adult CD4(+) recent thymic emigrants.

18 om the thymus, and survival of recent thymic emigrants.

19 nd to be functionally immature recent thymic emigrants.

20 identification and analysis of recent thymic emigrants.

21 n of CD62L(high) and CD69(low) recent thymic emigrants.

22 acer requires that all western Pacific Ocean emigrants acquire the (134)Cs signal, a radioisotope und

23 igration pattern, attenuates the response of emigrants against antigens that did not induce their del

24 TCR excision circles and CD31+ recent thymic emigrants and a substantial expansion of the active thym

25 ts of immune responses such as recent thymic emigrants and dendritic cells strongly relate to product

26 Recent advances in identifying thymic emigrants and development of safe methods to study thymi

27 ls, we traced the phenotype of recent thymic emigrants and found that most were CD44low.

28 thymocyte numbers, increasing recent thymic emigrants and improving TCR diversity of peripheral T ce

29 n vivo numbers of naive CD4(+) recent thymic emigrants and peripheral dendritic cells correlated well

30 re are age-dependent contributions of thymic emigrants and proliferation of postthymic T cells to mai

31 f FasR on the vast majority of recent thymic emigrants and resting peripheral T lymphocytes.

32 Whereas the frequency of recent thymic emigrants and the differentiation of induced Treg cells

33 esis by CD31(+) naive T cells (recent thymic emigrants) and homeostatic proliferation by Ki-67(+) T c

34 ntaining CD4 T cells (presumed recent thymic emigrants) and the counts of total T cells (r=0.65, P<0.

35 ased intrahepatic apoptosis of recent thymic emigrants appears in part responsible for lymphopenia in

36 Recent thymic emigrants are newly generated T cells that need to under

37 matory signals, and priming of recent thymic emigrants are not sufficient to maintain virus-specific

38 Th1 or Th2 cells and were not recent thymic emigrants as they were present in mice thymectomized bef

39 tics and reactivity from CD40L-deficient new emigrant B cells were similar to those from healthy dono

40 The protagonist, a child of Russian emigrants, became interested in antibodies as a postdoc

41 continues in the periphery in recent thymic emigrants, before these newly produced T cells gain func

42 A greater understanding of recent thymic emigrant biology has come with the development of method

43 rradiated hosts suggested that recent thymic emigrants can undergo homeostatic proliferation and acqu

44 All infants had fewer than 50 recent thymic emigrants (CD3(+)CD45RA(+)CD62L(+)) per cubic millimeter

45 originate from CD31(+)CD4(+) T recent thymic emigrants, CD31 was downregulated prior to secretion of

46 nal anti-CD4 and anti-CD31 and recent thymic emigrants (CD4+recently emigrated from the thymus (RTE),

47 8 (CD8N) T lymphocytes and CD4 recent thymic emigrants (CD4RTE) were quantified in the peripheral blo

48 ircles (TRECs) as a measure of recent thymic emigrant cells in peripheral blood lymphocytes of 50 HIV

49 he cells left the transitional recent thymic emigrant compartment.

50 Although new thymic emigrants contributed to the peripheral T cell response

51 een inward-migrating sensory neuroblasts and emigrant cranial neural crest cells (NCCs) play a role i

52 cell death contributes to the patterning of emigrant crest cells into three discrete streams.

53 These data suggest that brain-emigrant DCs are sufficient to support activated T cells

54 indicating that the cells were recent thymic emigrants derived from immature progenitors.

55 thymocyte export is reduced, and most thymic emigrants disappear rapidly from peripheral lymphoid tis

56 Under these conditions, thymic emigrants displayed the expected phenotype, that of matu

57 T cells (CD62L(hi)CCR7(hi)) from CXCR5(lo) 'emigrant' effector helper T cells and CXCR5(hi) 'residen

58 In vivo, however, thymic emigrants failed to induce an acute graft-versus-host re

59 s, with the characteristics of recent thymic emigrants, failed to move away from CXCR4-deficient feta

60 c proliferation in the absence of new thymic emigrants for maintenance of the naive peripheral pool.

61 We identified 256 seroprevalence surveys in emigrants from 52 countries (including 689,078 persons)

62 The number of emigrants from an origin depended on both its population

63 DR-positive DCs that migrated from the skin, emigrants from both dermis and epidermis, 60-80% express

64 compared to those typed in the South Indian emigrants from Malaysia and groups from Madras, Karnatak

65 lated to switched memory cells and are early emigrants from the germinal center reaction.

66 We hypothesized that DP-BB recent thymic emigrants have a shortened life span and disappear by ap

67 We show that a major subset of bone marrow emigrant immature human B cells, the transitional 2 (T2)

68 y, resulting in a frequency of recent thymic emigrants in aged mice that is similar to that of young

69 ssay to quantify the number of recent thymic emigrants in blood based on the detection of a major exc

70 owed that the concentration of recent thymic emigrants in blood decreased with age over a 2-log unit

71 Recent thymic emigrants in chickens transiently express the chicken T

72 s only a modest fall in recent CD4(+) thymic emigrants in secondary lymphoid tissues.

73 importance of peripheral T cells and thymic emigrants in the elicitation and maintenance of CD8 T-ce

74 role of regulatory T cells among new thymic emigrants in the induction of tolerance, we showed that

75 Measurement of recent thymic emigrants in the periphery thus provides an accurate ind

76 an nondivided eGFP(hi)CD44(lo) recent thymic emigrants in the periphery.

77 R4 expression is regained in FoxP3(+) thymic emigrants in the periphery.

78 ly arising T cells (so-called "recent thymic emigrants") in adults, as well as in babies.

79 C3-deficient naive T cells are recent thymic emigrants, indicating a block in T cell maturation.

80 s important for integration of recent thymic emigrants into the mature naive compartment.

81 activation and differentiation of new thymic emigrants is affected by chronic inflammation, as well a

82 The roles of emigrant Langerhans cells and corneal lymphatics in the

83 Here, we show that recent thymic emigrant maturation is a progressive process and is prom

84 eterogeneous subsets including recent thymic emigrants, mature naive phenotype cells, memory phenotyp

85 ent with this switch, recent FoxP3(+) thymic emigrants migrate exclusively to secondary lymphoid tiss

86 (3)-1574/mm(3)), a mean of 437 recent thymic emigrants/mm(3) (range, 196/mm(3)-785/mm(3)), and normal

87 r, these results point to the recruitment of emigrant monocytes and mononuclear cell granuloma format

88 The only marker on emigrants not found on either intrathymic cells or matur

89 s, but appears abruptly in the recent thymic emigrant population, suggesting that the lyp locus does

90 cell response are apparent in recent thymic emigrant populations, additional defects develop during

91 the appropriate regulatory cells from thymic emigrant precursors.

92 ut affecting thymocytes and/or recent thymic emigrants remains unknown.

93 CD8+ thymic emigrants require presence of MHC class I molecules in t

94 increased peripheral naive and recent thymic emigrant (RTE) populations, demonstrating its effect on

95 insight into the frequency of recent thymic emigrants (RTE) and, therefore, into thymic function.

96 Recent thymic emigrants (RTE) are an important subpopulation of naive

97 mice have poor accumulation of recent thymic emigrants (RTE) in the periphery.

98 used two approaches to isolate recent thymic emigrants (RTE) in young and aged mice and have compared

99 have been identified for these recent thymic emigrants (RTE), it is presently impossible to measure h

100 nd their exact relationship to recent thymic emigrants (RTE).

101 tudy, we show levels of CD8(+) recent thymic emigrants (RTEs) accounted for the prognostic power of a

102 udy we show that murine CD4(+) recent thymic emigrants (RTEs) are programmed to facilitate tolerance

103 Recent thymic emigrants (RTEs) are the youngest peripheral T cells tha

104 Recent thymic emigrants (RTEs) are the youngest subset of peripheral T

105 Recent thymic emigrants (RTEs) are the youngest T cells in the lymphoi

106 CD4(+) recent thymic emigrants (RTEs) comprise a clinically and immunological

107 epends on the context in which recent thymic emigrants (RTEs) encounter antigen.

108 fter developing in the thymus, recent thymic emigrants (RTEs) enter the lymphoid periphery and underg

109 have been used as markers for recent thymic emigrants (RTEs) in assessing human thymic function.

110 Using GFP to mark recent thymic emigrants (RTEs) in mice carrying a GFP transgene driven

111 ere we demonstrate that CD8(+) recent thymic emigrants (RTEs) migrated directly into the small intest

112 Recent thymic emigrants (RTEs) must undergo phenotypic and functional

113 levels of alpha4beta7 endowed recent thymic emigrants (RTEs) of unconventional types with higher SI-

114 Such recent thymic emigrants (RTEs) undergo both phenotypic and functional

115 These recent thymic emigrants (RTEs) underwent phenotypic maturation in the

116 )CD8(-)Foxp3(-) thymocytes and recent thymic emigrants (RTEs), contrarily to peripheral naive mature

117 ge as naive T cells, including recent thymic emigrants (RTEs), expanded preferentially, whereas the p

118 explore the TCR sensitivity of recent thymic emigrants (RTEs), we triggered T cells with altered pept

119 gous graft-vs-host disease are recent thymic emigrants (RTEs).

120 cells in CSA-treated rats are recent thymic emigrants (RTEs).

121 ytometry measurements of CD31+ recent thymic emigrants (RTEs).

122 t contains a high frequency of recent thymic emigrants (RTEs).

123 ture CD8 T cells with those of recent thymic emigrants (RTEs).

124 e youngest peripheral T cells (recent thymic emigrants [RTEs]) are functionally distinct from naive T

125 hese T cells may not represent recent thymic emigrants, since naive T cells may maintain this phenoty

126 New B cell emigrants slowly transited the HEV perivenule space, and

127 assessed by quantification of recent thymic emigrants, T-cell receptor excision circle levels, and T

128 underdeveloped cities with large numbers of emigrants than would be expected by chance (p = 0.011; b

129 ircles (TRECs), a molecular marker of thymus emigrants that have divided few times after leaving the

130 hat TCR revision is limited to recent thymic emigrants that have maintained RAG expression and TCR lo

131 ells, and activated alloreactive CD8+ thymic emigrants that have repopulated the periphery after tole

132 t of the surface markers on alphabeta-thymic emigrants (Thy1, CD44, CD69, CD25, leukocyte functional

133 igrants (graft to thymus pathway) and thymic emigrants (thymus to graft pathway) are involved in tole

134 s CTLA-4, which could dampen the response of emigrants to peripheral antigens.

135 maturation, T cells egress as recent thymic emigrants to peripheral lymphoid organs where they under

136 rather than from increased trafficking of BM emigrants to peripheral lymphoid tissues.

137 w incidence of breast cancer, but that among emigrants to the United States, the second generation, b

138 a region with lower CHB rates, but many more emigrants to the United States.

139 This enables some recent thymic emigrants to undergo LIP and convert into long-lived mem

140 We found that before HSC-GT, new emigrant/transitional and mature naive B cells from ADA-

141 New emigrant/transitional and mature naive B cells from AID-

142 We found that new emigrant/transitional and mature naive B cells from carr

143 The antibody-coding genes from new emigrant/transitional and mature naive B cells were clon

144 with decreased frequency of autoreactive new emigrant/transitional B cells exiting the BM, indicating

145 nd reactivity of antibodies expressed by new emigrant/transitional B cells from IPEX patients were si

146 We found that new emigrant/transitional B cells from patients with XLP wer

147 e normally low frequency of polyreactive new emigrant/transitional B cells in DOCK8-deficient patient

148 The FoxP3(+) thymic emigrants undergo the second switch in trafficking recep

149 ve contribution of CD4 and CD8 recent thymic emigrants was modulated as they entered the peripheral T

150 ng gene 2 promoter to identify recent thymic emigrants, we now show that T cell differentiation conti

151 in the face of increasing numbers of thymic emigrants, whereas IL-7 potently accomplished this.

152 Trajectory simulations show that 80% of emigrants will reach regions suitable for winter breedin

153 We hypothesized that recent thymic emigrants with regulatory function are important in the

154 main subset consists of naive recent thymic emigrants, with effector memory T cells (T(EM)) found on

155 Levels of recent thymic emigrants within the peripheral blood were assessed thro