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1 bes for biomedical research and diagnostics, emphasizing the needs and opportunities that have been u
2 remodeling beyond a mere structural role and emphasize the need for a better understanding of this mo
3 fication associated with MGP dysfunction and emphasize the need for a comprehensive approach to this
8 In this review, we summarize recent work and emphasize the need for a solid theoretical framing to gu
12 clinical relevance of the molecular data and emphasize the need for careful parental assessments and
14 ve dichotomous effects on TLR4 signaling and emphasize the need for caution in interpreting the resul
21 H1N1 viruses with avian influenza virus and emphasize the need for continued surveillance of influen
22 t can both directly or indirectly damage DNA emphasize the need for developing facile methods to asse
23 -term implications of active coeliac disease emphasize the need for early detection and strict adhere
24 f sampling effort as an explanatory variable emphasize the need for effective monitoring and risk ass
26 raphic differences in these associations and emphasize the need for further investigation of eating d
27 he essential role of RAD21 in eukaryotes and emphasize the need for further understanding of the role
30 however, current relapse and mortality rates emphasize the need for improved therapeutic strategies.
31 of CR6261 and CR9114 against H2 viruses and emphasize the need for in vivo evaluation of bNAbs.IMPOR
32 the crucial importance of female choice and emphasize the need for incorporating between-individual
39 e use of higher-order reasoning schemes that emphasize the need for multiple perspectives, allow for
40 mple of the antibiotic-resistance crisis and emphasize the need for new approaches to treat and preve
42 ic study of the human inner ear continues to emphasize the need for non- or minimally invasive clinic
43 malaria and insecticide-resistant mosquitoes emphasize the need for novel methods of disease control.
45 rspective, it is important for clinicians to emphasize the need for parental adherence to a child's t
47 vitamin E treatment in the SELECT trial and emphasize the need for preclinical studies using accurat
48 rities in the occurrence of DM, CKD, and HTN emphasize the need for prevention and treatment options
49 es, not simply reflecting greater adiposity, emphasize the need for prevention strategies starting in
51 ulted specifically from exome sequencing and emphasize the need for rigorous statistical evaluation o
52 incidence in these North American cities and emphasize the need for scale-up of opioid agonist therap
56 n the geomechanical responses of these sites emphasize the need for systematic geomechanical appraisa
57 rtance for decision making, and, as such, we emphasize the need for the functioning of an endocarditi
58 valid in vitro models of malignant cells and emphasize the need for validation of primary tumor cultu
60 rapid growth of candidate novel markers has emphasized the need for a systematic approach to their e
62 the global outbreak of an influenza pandemic emphasized the need for an effective vaccine adjuvant.
63 e and formidable immune evasion arsenal have emphasized the need for more effective antimicrobial app
64 zing radiation (IR) to large populations has emphasized the need for rapid and reliable methods of bi
66 s for the current gene therapy strategy that emphasizes the need for a combinatorial therapy to both
67 everity of disease, morbidity, and mortality emphasizes the need for a culture method that permits si
68 multiple renal, hepatic and splenic lesions emphasizes the need for a high index of clinical suspici
70 en across the different developmental stages emphasizes the need for a holistic life-cycle approach t
72 ally limited to surgery and radiation, which emphasizes the need for better understanding of this dis
73 a recent Q fever outbreak in the Netherlands emphasizes the need for better understanding this unique
74 ive biology of mechanosensitive channels and emphasizes the need for care in analysing protein comple
77 and Ag NPs and enhance their toxic potential emphasizes the need for conducting future toxicity studi
78 rising in Hg(II) bioassays with cysteine and emphasizes the need for considering changes in chemical
81 g the current published recommendations, and emphasizes the need for evidence-based guidelines and un
83 al mus-scale transitions in the loops, which emphasizes the need for extended simulations in studies
84 in the presence of sequence polymorphism and emphasizes the need for extreme caution and thorough pri
88 for chronic musculoskeletal manifestations, emphasizes the need for identification of genetic determ
89 and nurse-patient interaction of nurses and emphasizes the need for implementing institutional polic
92 on of attrition and nonignorable missingness emphasizes the need for longitudinal diagnostics and for
95 into the pathogenic mechanisms involved and emphasizes the need for more complex yet tractable exper
99 domains that are conformationally flexible, emphasizes the need for new approaches for modeling RNA
101 ancy even in the most recent calendar period emphasizes the need for new treatment options for these
104 oacrylate generated by metabolic enzymes and emphasizes the need for RidA to quench this reactive met
105 ch as the zwitterionic Fos-choline-12, which emphasizes the need for simple validation assays like th
106 etween traditional prognostic markers and RS emphasizes the need for standardized assessment and supp
109 oxidation byproducts as NDMA precursors and emphasizes the need for their consideration when evaluat
110 on of the 2009 pandemic H1N1 influenza virus emphasizes the need for universal influenza vaccines tha
111 -arterial treatment of acute ischemic stroke emphasizes the need for well designed prospective studie
114 ance the treatment of rectal cancer, further emphasizing the need for a multidisciplinary approach to
115 r, the risk of severe HT rises considerably, emphasizing the need for a readily available assay of DE
116 he true heritability is bounded away from 0, emphasizing the need for accurate confidence intervals.
117 ndations for future miRNA biomarker studies, emphasizing the need for accurate interpretation within
118 are vertically infected with HIV-1 annually, emphasizing the need for additional interventions to eli
119 likely larger than that for the State total, emphasizing the need for additional measurements in unde
120 ine inactivation of Cryptosporidium oocysts, emphasizing the need for additional pool remediation opt
122 combined with a low treatment satisfaction, emphasizing the need for adequate treatment, especially
124 fficient to reduce mortality in endotoxemia, emphasizing the need for APC's cytoprotective actions, b
125 inics, and neurovascular emergency services, emphasizing the need for appropriate blood-sensitive mag
127 mmentary highlights the article by Ng et al, emphasizing the need for autopsies to better model infec
128 d model compared with the LeuBAT structures, emphasizing the need for careful experimental verificati
130 ained by the variation of single parameters, emphasizing the need for comprehensive sensitivity analy
131 een computational and experimental chemists, emphasizing the need for computation to predict experime
132 ip between vitamin D and asthma and allergy, emphasizing the need for controlled, prospective studies
133 l, community, and agricultural settings; and emphasizing the need for establishing regional active su
134 fe style factor affecting human health, thus emphasizing the need for evidence-based dietary guidelin
135 mass fractions of Na less than 4 mg kg(-1), emphasizing the need for exact matching of matrix compos
136 entified using traditional linkage analysis, emphasizing the need for exome sequencing of complex lip
138 atterns were encountered in 31% of patients, emphasizing the need for further evaluation in larger se
139 gnificant spatial variability in subsidence, emphasizing the need for further measurement, which coul
140 e cause of this structure remains equivocal, emphasizing the need for further molecular characterizat
141 patially and temporally resolved (13)C MRSI, emphasizing the need for further MR methodologic develop
142 directions for isoform function prediction, emphasizing the need for heterogeneous genomic data inte
143 y recipient tumor cells were not detectable, emphasizing the need for improved additive MiHA-specific
144 ng other countries in the region and beyond, emphasizing the need for improved EV-A71 surveillance an
145 fects on lung function and disease severity, emphasizing the need for improved pediatric asthma contr
146 of the burden of these diseases on society, emphasizing the need for increased attention toward adva
147 from these large collaborative initiatives, emphasizing the need for life-long follow-up of survivor
148 phase-locking is disturbed in schizophrenia, emphasizing the need for more studies of oscillatory syn
149 r from interobserver diagnostic variability, emphasizing the need for new diagnostic modalities.
150 fectiveness for risk stratification, further emphasizing the need for optimal patient selection for c
151 ly from published sets and between patients, emphasizing the need for patient-specific adjustment.
153 d in the United States over the past decade, emphasizing the need for rapid and accurate tests for CD
155 ity is generally determined by liver biopsy, emphasizing the need for simple noninvasive methods for
156 are crucial for cell-to-cell communication, emphasizing the need for spatially resolved data on cyto
157 y responses required T cell help to develop, emphasizing the need for T-B collaboration for long-term
158 rvival in survivors who develop CVD is poor, emphasizing the need for targeted prevention strategies
159 measured in infancy persist into childhood, emphasizing the need for targeted therapeutic interventi
160 tion with corresponding lung volume changes, emphasizing the need for tight control over lung volume
161 8 of 1231] vs 3.7% [121 of 3311]; P < .001), emphasizing the need for timely advanced treatment.
162 th photoreceptor degeneration in the Tg rats emphasizes the need in behavioral therapeutic studies fo
165 of nephrocalcinosis and that our case series emphasizes the need of a well-organized retrospective st
166 ss preclinical tests fail in these patients, emphasizing the need of improved preclinical models to t
170 biased degradation among genomic regions and emphasize the need to assess sample integrity immediatel
172 -induced disease exacerbation in rodents and emphasize the need to better understand the basic mechan
173 entions for preventing or curing the disease emphasize the need to better understand the genes involv
174 calculators to tropical farming systems and emphasize the need to broaden the scope of the underlyin
176 ease patients with early visual symptoms and emphasize the need to clarify the pathophysiological cha
178 assumes negative effects of nonnatives, and emphasize the need to consider context-dependence and in
182 grees of visual impairment in these patients emphasize the need to continue refining our understandin
184 nderestimate AZT resistance levels, and they emphasize the need to develop subtype-specific genotypic
185 processes from degeneration, these findings emphasize the need to develop therapeutics aimed at axon
191 n as a function of juvenile density and time emphasize the need to evaluate their roles through later
192 t into how a small molecule binds an IDP and emphasize the need to examine motions on the low microse
193 on in the development of the human tumor and emphasize the need to experimentally determine the signi
195 transmissibility of influenza viruses and we emphasize the need to find better predictors of both sea
196 ct of initial conditions and seasonality and emphasize the need to focus on appropriate characterizat
201 s and the lack of targeted therapies for TSS emphasize the need to identify key players of the storm'
202 n development for alcohol use disorder (AUD) emphasize the need to identify novel molecular targets a
204 eformation connections described in our work emphasize the need to include metamorphic and fluid tran
209 GWAS, disease genomics, and gene therapy and emphasize the need to investigate both types of mutation
210 pes can be maintained within populations and emphasize the need to investigate interactions between s
211 are dependent upon the microbial context and emphasize the need to investigate various infection mode
215 cts on the exchange of greenhouse gases, and emphasize the need to project future hydrological regime
218 iomyelitis infection in Pakistan and further emphasize the need to scale-up clinical and environmenta
219 side effects is rather small, these data do emphasize the need to select patients carefully for RRA
221 igratory bird breeds throughout its life and emphasize the need to understand how events throughout t
225 ed from the Great East Japan Earthquake have emphasized the need to develop strategies to respond to
226 energy costs and environmental concerns have emphasized the need to produce sustainable renewable fue
230 chwann cell function in the adult animal and emphasizes the need to approach potential therapeutic mo
232 ential for permanent hearing impairment also emphasizes the need to better understand and manage this
233 ed to aged or ovariectomized female mice and emphasizes the need to combine histopathological and fun
239 direct and indirect economic effect of ASDs emphasizes the need to continue to search for effective
240 ver, the emergence of drug-resistant mutants emphasizes the need to develop additional agents that ha
241 larly aging, converge on the vessel wall and emphasizes the need to develop effective strategies to i
242 hey will be captured by limited biopsies and emphasizes the need to develop therapies specifically ta
244 prognosis and lack of efficacious treatment emphasizes the need to elucidate the pathways playing a
245 f the hollow core fibril at physiological pH emphasizes the need to examine toxic effects of minor ol
247 hallenge that prediction algorithms face and emphasizes the need to experimentally validate predicted
248 t part of EU raw material consumption, which emphasizes the need to focus on the full production chai
251 heir higher mortality and progressive course emphasizes the need to identify AR-HIES patients early,
253 factors that regulate gene expression, which emphasizes the need to include chromatin structural para
255 ing processes in functionally important ways-emphasizes the need to integrate multiple mechanisms of
258 ange may lead to more variable food quality, emphasizes the need to maintain and strengthen existing
259 for MSC-derived resistance to forodesine and emphasizes the need to move toward combinations with age
260 an outperform their natural counterparts and emphasizes the need to optimize donor-acceptor distance
261 POLG2 mutations in mitochondrial disease and emphasizes the need to quantitatively characterize the b
262 the dwarfed phenotype of the mutant and thus emphasizes the need to re-address the proposed role of P
264 artifacts in cancer genomics data, our study emphasizes the need to survey the diversity of normal as
265 in cancer cells that prevents apoptosis, and emphasizes the need to synergize nanoparticle design wit
267 or regulating histone demethylase levels and emphasizes the need to tightly regulate chromatin modifi
269 d protein in mice versus human patients, and emphasizes the need to understand species-specific prote
270 n shaping geographic diversity patterns, and emphasizes the need to understand the mechanisms underpi
271 quent use of macaques in biomedical research emphasizes the need to understand the molecular basis of
273 % of infections were identified on days 0-3, emphasizing the need to address maternal and environment
274 ALAN can broadly effect migratory behavior, emphasizing the need to better understand the implicatio
275 regulating commercial sex are also reviewed, emphasizing the need to carefully consider the medical a
276 h significantly increased risk for bleeding, emphasizing the need to carefully determine if and when
277 and effector functions, with the differences emphasizing the need to carefully interpret preclinical
278 d significantly below the theoretical yield, emphasizing the need to computationally investigate and
279 e relative richness of these three families, emphasizing the need to consider the incomplete nature o
280 pposed to warm summers on a signaling trait, emphasizing the need to consider year-round influences o
282 female and male heart is currently unknown, emphasizing the need to define human myocardial biology.
283 irreversible EGFR kinase inhibitors further emphasizing the need to develop more potent therapies ag
284 ly associated with platinum drug resistance, emphasizing the need to directly measure the intratumor
285 atory and cytoskeletal remodelling pathways, emphasizing the need to explore biochemical alterations
286 for patients with CAPS and residual disease, emphasizing the need to explore other NLRP3-mediated pat
287 nt predators on prey metacommunity assembly, emphasizing the need to explore the role of predator die
288 xicities that are unique to immunotherapies, emphasizing the need to familiarize the oncology practit
289 e >70 affected individuals reported to date, emphasizing the need to identify the underlying genetic
290 ate C.albicans-mediated mucosal inflammation emphasizing the need to optimize the applied antifungal
292 trum to that found in the adult counterpart, emphasizing the need to promote sun protection practices
293 stimulate T cell responses in vivo, further emphasizing the need to regulate both pathways to induce
294 inst a backdrop of nutrient over-enrichment, emphasizing the need to separate these effects to gauge
295 traditional stoves with clean technologies, emphasizing the need to shift in the long term to near e
296 and quality of life (QOL) they have enabled, emphasizing the need to sustain our national investment
297 f diversity and eutrophication on stability, emphasizing the need to understand how drivers of global
298 altered our understanding of tumorigenesis, emphasizing the need to understand how single stem cells
299 set by natural disasters are also presented, emphasizing the need to understand the magnitude frequen
300 resistance have proven to be heterogeneous, emphasizing the need to use broad therapeutic approaches
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