ライフサイエンスコーパス: emulate

1 but examples of this are rare and not easily emulated.

2 matopoietic stem/progenitor (CD34+) cells to emulate a natural mutation, which deletes the MCS-R2 alp

3 The principal motifs emulate a network of meshed gears.

4 o be evaluated with respect to how well they emulate a particular target trial.

5 ity of the mammalian transcription factor to emulate a prokaryotic repressor.

6 curve; ie, restricted mean survival time) to emulate a randomized clinical trial.

7 es (big data) can be viewed as an attempt to emulate a randomized experiment-the target experiment or

8 In addition, we use this framework to emulate a serial sectioning electron microscopy experime

9 The observational data were used to emulate a target trial with 2 groups: colonoscopy screen

10 To address this, we emulated a social situation where one's voluntary action

11 A carbon nanotube (CNT) synapse emulates a biological synapse with its dynamic logic, le

12 enyl)propynyl]benzene (3A), a structure that emulates a gyroscope with a p-phenylene group acting as

13 developed a microfluidic device (chip) that emulates a mucosal surface experiencing constant fluid f

14 The scheme is suitable for emulating a range of spin-spin interactions, but to char

15 odels that contained three 20 mm(2) channels emulating a sandy loam microstructure.

16 rn generators (hCPGs) that may be trained to emulate accurately the dynamical response of biological

17 s surprisingly easy to program this model to emulate actual performance in four very different but we

18 cally pure (-)-epicatechin to humans closely emulated acute vascular effects of flavanol-rich cocoa.

19 c model for the action of Zn(2+) on DAT that emulated all current experimental observations and accou

20 es of three replicate estuarine mesocosms to emulate an abrupt nanoparticle release event to a tidal

21 Protein Structure Motif Search program that emulates an expert.

22 mposed of a spike generator, a dynamic clamp emulating an excitatory plastic synapse, and a chemicall

23 environments and experimental challenges in emulating an in vivo lipid environment.

24 ns embedded within a 3D collagen matrix that emulates anatomical vasculature more closely than inorga

25 e buoyed by new, multifaceted materials that emulate and coercively interact with the local microenvi

26 t enzymes, it provides a modular platform to emulate and investigate hepatic metabolism processes, wi

27 arious physical systems have been studied to emulate and solve this Ising problem.

28 IL-1beta emulated AP-1, HIF-1, and NF-kappaB DNA binding during h

29 a confirm that increases in excitability can emulate APC.

30 ess will critically depend on our ability to emulate aspects of depressive symptomatology and treatme

31 Artificial grammars (AG) are designed to emulate aspects of the structure of language, and AG lea

32 RNA structured to emulate bacterial patterns constitutes a novel vaccine s

33 At a relatively low concentration, DAHP emulates BH4 and engages the GFRP-dependent feedback inh

34 terest in constructing physical systems that emulate biological functionality more directly, with the

35 earn asocially, imitate, receive teaching or emulate by examining baskets made by previous chain memb

36 However, clinical situations are emulated by a GC intervention initiated in the midst of

37 Such a field can be emulated by coupling the chain to a central spin initial

38 s of flexible margins found in nature can be emulated by human-engineered propulsors.

39 In other slices, APC was emulated by inducing spreading depression (as determined

40 This degradative effect cannot be emulated by iron or free protoporphyrin, two major chemi

41 This effect was emulated by normal retinal glia and appeared to be media

42 ssive effect of 2-AG on TRPV1 activation was emulated by positive modulators of the protein kinase A

43 Formation of such granules was emulated by treatment of mouse brain extracts and human

44 these five representative ones could also be emulated by using the same chromatographic systems.

45 d HIV-1 neutralizing antibodies that closely emulate CCR5 and demonstrate that tyrosine sulfation can

46 Synthetic glycopolymers that emulate cell-surface mucins have been used to elucidate

47 We have used peptides emulating central regions of human occludin's first and

48 uroscientists have developed models that can emulate changes seen in the primary motor cortex during

49 We used parameter scanning to emulate changes to the limiting rate for steps in a fitt

50 or under a number of culture conditions that emulate characteristics of 3D stem cell niches.

51 Our results indicate that this model, which emulates clinically relevant intestinal radiation-induce

52 for rapid uncaging in arbitrary patterns to emulate complex neural activity.

53 morphic engineering have made it possible to emulate complex neuronal ion channel and intracellular i

54 ar catalysts for H2 production and oxidation emulate components of the active site of hydrogenases.

55 Wessim emulates conventional exome capture technologies, includ

56 cer cells in MCF7 spiked human blood samples emulating CTCs in human blood.

57 ne arm, we show that they can be employed to emulate desired nonlinear dynamical systems.

58 ynthetic gene networks can be constructed to emulate digital circuits and devices, giving one the abi

59 in concentrations and conditions designed to emulate distinct states of DNA condensation, with focus

60 This process effectively emulates drug-conjugate delivery, drug release, and drug

61 approach, applicable to any gene fusion, to emulate effects of translocations found in human cancers

62 carefully calibrated visual stimulation that emulated either congruent or opposite stimulation condit

63 o requires walls with controllable output to emulate electronic nano-components such as diodes and tr

64 ould promote neuroprotective strategies that emulate endogenous homeostatic responses to ASOX (e.g.,

65 model of chronic inflammatory bowel disease-emulating events in human colon cancer.

66 via four types of protocols, three of which emulating experiments from the literature, and observed

67 rom bacteria grown in conditions designed to emulate extra- or intracellular environments in vivo.

68 state has meant that only a few attempts at emulating Fermi-Hubbard physics on solid-state platforms

69 To emulate gene expression experiments, we developed a mode

70 omonas gingivalis increased under conditions emulating gingivitis.

71 ted tissue units and the modular assembly to emulate hierarchical tissues will be discussed.

72 to therapy in tumors in TH-MYCN mice, which emulate high-risk neuroblastoma in children.

73 multaneously fired laser beams heat ignition-emulate hohlraums to radiation temperatures of 3.3 milli

74 oprevention, animal models must both closely emulate human disease and possess surrogate endpoint bio

75 g number of in vitro and in vivo models that emulate human disease pathology is aiding scientists in

76 on SCI model in rats with abnormalities that emulate human post-SCI pathophysiology, including sponta

77 ack of small animal models that consistently emulate human responses to these toxins.

78 their efficacy in animal models that closely emulates human disease.

79 s type 1 (HIV-1) infection that more closely emulates human heterosexual transmission by use of multi

80 one profound improvements in the fidelity of emulating human disease.

81 d innate immune responses in Cmah(-/-) mice, emulating human loss of the gene encoding production of

82 tion should provide a unique in vitro system emulating human type 2 diabetes mellitus.

83 Molecules that emulate in part the remarkable capabilities of protein m

84 ological template suggests new directions to emulate in the pursuit of new high-performance, multifun

85 activating Wnt and Fgf signalling, timed to emulate in vivo development.

86 This spin model can be emulated in a natural way with Rubidium and Caesium atom

87 whether adult-onset neurodegeneration can be emulated in short-term cultures and the hurdles of cell

88 nce the preserve of biology, has been widely emulated in software, while physically embodied systems

89 biological composites have been successfully emulated in synthetic systems using inkjet-based, direct

90 nt during active network states in vivo were emulated in vitro.

91 This emulates in a controlled manner the proton-withdrawing c

92 to classify solid tumors has not been widely emulated, in part due to more limited understanding of e

93 These synthetic glycopeptides emulate intermediate structures, not otherwise readily a

94 , we developed an in vitro invasion assay to emulate invasion into the extracellular matrix.

95 ctivator phorbol myristate acetate could not emulate IPC, but blockade of PKC activation with chelery

96 NMDA, Ca2+, and epsilonPKC was found when we emulated IPC with the diacylglycerol analog oleoylacetyl

97 he nursing contribution was most valued when emulating it.

98 ptide binds in a hydrophobic pocket that may emulate its potential interaction with the host cell mem

99 onch shell architecture creates a barrier to emulating its cross-lamellar structure in synthetic mate

100 ational capability of the nervous system and emulating its functionality.

101 ingle-cell model of a human hepatocyte which emulates key features of a hepatocyte is likely to be va

102 ract tissues, kidney, and liver, potentially emulating key features of human ZIKV infections, most of

103 to test the fit after parameter estimation, emulating Lilliefors's tests.

104 aminations truncated at different lengths to emulate limited-whole-body data.

105 domains in cholesterol-rich model membranes emulate lipid rafts in cell plasma membranes (PMs).

106 of molecular crystals with units intended to emulate macroscopic gyroscopes and compasses.

107 licobacter hepaticus-infected Rag2(-/-) mice emulate many aspects of human IBD, and our recent work u

108 licobacter hepaticus-infected Rag2(-/-) mice emulate many aspects of human inflammatory bowel disease

109 Whereas recent, sporadic GEMMs emulate many aspects of their human disease counterpart

110 man immunodeficiency virus (SHIV)-AD8, which emulates many of the pathogenic and immunogenic properti

111 dded to the simulation results several times emulating measurement replicates, before expression rati

112 correct statistical methods, perhaps through emulating methods described in previous research, calls

113 y to Plasmodium, or design of human vaccines emulating mosquito resistance to the parasite, require e

114 mental protocols using mice, with the aim to emulate most closely the increased skin cancer risk in o

115 the design of biomimetic artificial systems emulating multicluster-binding proteins, with the final

116 lso opens a path for implementation in brain-emulating nanochips comprised of networks of noisy spiki

117 e late-successional species, strategies that emulate natural disturbance regimes are often advocated,

118 form comprising synthetic glycopolymers that emulate natural mucins arrayed at different surface dens

119 at strikes a landscape-level balance between emulating natural disturbances in order to attract indiv

120 ustically forced to oscillate at a frequency emulating natural flame flickering behavior.

121 rojecting salamanders catching walking prey, emulating natural foraging conditions.

122 We emulate nature's toughening mechanisms by combining two

123 en carbide spherical indenter (r = 3.18 mm), emulating occlusal loading on crowns supported by dentin

124 nhibitors, SB216763(SB21) or SB415286(SB41), emulate OIC.

125 Fluorescence intensity decay curves emulated on the basis of the MD trajectories showed good

126 ous in vitro models have been described that emulate one or more of the processes involved in angioge

127 Here we emulate optimum natural systems following Murray's law u

128 p to pinpoint practice styles that should be emulated or avoided.

129 l entrainment of natural brain oscillations, emulating oscillatory signatures activated by cognitive

130 rently confined to China, MCR-1 is likely to emulate other global resistance mechanisms such as NDM-1

131 imal models for these disorders are built to emulate our understanding of the clinical diagnosis, wit

132 s paper uses individual micro controllers to emulate p-bits, and we present results for a 4-bit rippl

133 The treatments emulated patterns of observed diurnal, seasonal, and ann

134 allows a rapid rise in dopamine from stimuli emulating phasic firing patterns associated with incenti

135 Our triad emulates photosystem II more closely than previously inv

136 s changes (4200 to 1.6 MPa) upon exposure to emulated physiological conditions.

137 be visualized directly using micromodels to emulate pore-scale geometries.

138 y, we have developed a novel methodology for emulating positive and negative selective pressure in vi

139 nation in preconditioned slices and after NO-emulated preconditioning (90.0+/-17.7% and 90.0+/-21.3%,

140 raise the question if vaccines, which try to emulate protective natural immune responses, should elic

141 intermediates, and (iii) configurations that emulate R-loop structures that arise during class switch

142 wn intrinsic classification difficulties and emulate real-world scenarios.

143 oncentration and composition in an effort to emulate real-world sensing conditions.

144 te how this is mediated within the brain, we emulated real-time social monitoring of participants' pe

145 fully answer synthetic questions designed to emulate reasoning and inference problems in natural lang

146 amplitude-only diffractive optical elements emulate refractive lenses without the need of large prof

147 By emulating remodelling of biomaterials, this model system

148 rithm using a simulated (1)H NMR data set to emulate renal tubule toxicity and further exemplified th

149 The ultimate goal is to emulate resources such as the Virtual Observatory of the

150 icancer agents may be diminished and may not emulate results achieved in registration trials.

151 n mice causes a skin and hair phenotype that emulates scarring alopecia.

152 oxidase B (MAO-B) is overexpressed and which emulates several features of PD.

153 ur targeted structures, in particular, those emulating sheet-like structural aspects using poly(p-phe

154 usible dynamic regimes of our new model that emulate simultaneously experimental data for a wide rang

155 Here, emulated soil micromodels were used to measure transport

156 all of the peptoid-based mimics studied here emulated SP-C's secondary structure, forming stable heli

157 neered intrinsically innervated human IAS to emulate sphincteric physiology in vitro.

158 echnology that decodes cortical activity and emulates spinal cord CPG function allowing volitional rh

159 ly metastatic 4T1 breast cancer model, which emulates stage IV breast cancer in humans.

160 much softer or stiffer gels, including gels emulating stiff dystrophic muscle, cells do not striate.

161 us peak contrast-diameter products (CD) that emulated subtle tissue-equivalent lung nodules were nume

162 three-dimensional physical electronic system emulating synapse networks could be built, that would be

163 resistive switching memory is engineered to emulate synaptic devices.

164 mplanted both in the brain and peripherally, emulating systemic cancer metastasis, tumors inside and

165 on a sample stick in a manner that begins to emulate that of a "card-swipe" system.

166 aerosolize nicotine and produce a vapor that emulates that of cigarettes but purportedly has fewer tr

167 rest in creating printing platforms that can emulate the 4D nanostructure - including both the chemic

168 is flexible and at the appropriate level can emulate the activity of a weak ligand like Vn.

169 , apo A-I dissociation, and particle fusion, emulate the activity of human plasma phospholipid transf

170 Mimics were designed to emulate the amphipathic patterning, helicity, and hydrop

171 pplementation with resistant starch does not emulate the apparently protective effect of diets rich i

172 microwave photon, we demonstrate that we can emulate the basic effects of weak localization.

173 C1Bdelta less responsive to DAG and thereby emulate the behavior of C1B domains from conventional PK

174 et/carbon-nanotubes (LGC), are fabricated to emulate the behavior of Li metal and Li-free Li metal an

175 Carbon monoxide-releasing molecules (CO-RMs) emulate the beneficial (e.g., anti-inflammatory) effects

176 are often used experimentally in attempts to emulate the bioactivities of endogenous NO, but the phar

177 utations in periplakin have the potential to emulate the cataract seen in lenses with defective BF pr

178 We are trying to emulate the cell-specific consequences of chromosomal tr

179 Such findings emulate the clinical scenario; therefore, ICSS for disco

180 Creating synthetic chemical systems which emulate the complexity observed in cells relies on explo

181 romise of biofunctionalizing HA hydrogels to emulate the complexity of the natural cell microenvironm

182 State and artificial groundwater prepared to emulate the conditions at the site.

183 razol-3-yl)-2'-deoxycytidine monomer Z, that emulate the conformation of W.

184 This catalytic approach has been utilized to emulate the coumarin biosynthesis pathway, which feature

185 These kinetics emulate the decline in HIV-1 produced from short-lived C

186 that uses a quasi-kinetic search process to emulate the diffusional encounter of two proteins and to

187 We used the qudit to emulate the dynamics of single spins with principal quan

188 To emulate the effect of crowding in cells, we studied acto

189 Here, we describe an approach to emulate the efficiency of these natural reaction cascade

190 However, their potential to emulate the electromechanical milieu of native tissues o

191 s the assemblage of chemical structures that emulate the elements of macroscopic rotary devices, such

192 sign and synthesis of abiotic compounds that emulate the exquisite complex structures and/or function

193 nanomaterials in solution due to a desire to emulate the exquisite structure and function of Nature's

194 hecker PRISM, demonstrating their ability to emulate the function of asynchronous components under lo

195 subsequent elution to NMR tubes was done to emulate the function of HPLC-NMR for dereplication purpo

196 Systems chemistry aims to emulate the functional behavior observed in living syste

197 hat the putative PirAB(vp) heterodimer might emulate the functional domains of the Cry protein, and i

198 in in vitro liver platforms is essential to emulate the functions of the liver, and its overall resp

199 low-energy consumption and could potentially emulate the functions of the neuronal network.

200 hieve this level of sensitivity, which would emulate the highly evolved and tailored reaction network

201 and a mixture of the three P450s designed to emulate the human liver.

202 ([(Tol)Im(F4)](+)Br(-)) that was designed to emulate the hydride acceptor properties of methenyl-H4MP

203 using atomic fermions in optical lattices to emulate the mathematical models that have been used to s

204 r GlgEI (Sco GlgEI-V279S) was made to better emulate the Mtb GlgE M1P binding site.

205 en inserted randomly in the genome, they can emulate the native environment of a gene resulting in a

206 representing the ictal and postictal states, emulate the observed dynamics.

207 tics of an otherwise sub-optimal operator to emulate the optimal cat-state measurement.

208 and nitroamino substituents are expected to emulate the parent compound which was shown to form crys

209 d in their ability to create conditions that emulate the physical and biochemical constraints of real

210 effects during PCA infusion thus appeared to emulate the physiological regulation of intravascular bl

211 rains with late-life lupus predisposition to emulate the polygenic nature of this disease.

212 usly replaced with appropriate modulators to emulate the presence of linker vacancies, resulting in t

213 on a two-dimensional (2D) square lattice to emulate the quasi-2D micromass culture extensively used

214 e sensory and adjacent transmembrane domains emulate the structural changes caused by cytokinin bindi

215 he Hg-C bond in mercury-alkyl compounds that emulate the structure and function of the organomercuria

216 the multitude of cellular oncoproteins that emulate the transforming function of ST.

217 tificial quantum systems that can be made to emulate the underlying Fermi-Hubbard models.

218 Furthermore, 13 emulated the ability of heterogeneous R. sin-1 LPS to an

219 id, a known inhibitor of Delta9-desaturases, emulated the effect of isoxyl on oleic acid synthesis bu

220 When we emulated the forces of the T cell using the AFM cantilev

221 r of cd73-deficient Tregs into Rag(-/-) mice emulated the observed phenotype in cd73(-/-) mice, while

222 We emulated the repeated, short-term exposures that migrati

223 Moreover, the IgG responses in macaques emulated the targeting to specific regions of Env known

224 malian cells, whereas heterofusion receptors emulated the transregulatory properties of the ERalpha d

225 pathogenic A391E mutation in FGFR3 TM domain emulates the action of fgf2, trapping the FGFR3 dimer in

226 Forced expression of MRTF-A precisely emulates the anti-inflammatory effect of BMP4, while MRT

227 products expeditiously and in a manner that emulates the biogenesis proposed for these compounds.

228 scoring matrix as bits in computer words and emulates the calculation of scores by a series of logic

229 modified embryonic stem (ES) cell line that emulates the early embryonic demethylation and remethyla

230 erate peptide unwinding from each end, which emulates the effect of increasing temperature.

231 d that TAPNAC promoter-driven GUS expression emulates the expression of TAPNAC mRNA in anthers.

232 Phe-43 emulates the function and position of the critical inter

233 This synthetic analogue 5(x-) emulates the heteroleptic {His2Cys2} ligation of the [2F

234 odilator and vasoconstrictor activity, which emulates the human physiological response subserving O(2

235 e of the thioredoxin reductase system, which emulates the intracellular redox potential, CyaY fails t

236 gically inspired antireflective surface that emulates the intricate surface architectures of leafhopp

237 rk of stochastic context-free grammars, that emulates the kinetics of RNA folding in a simplified way

238 al fracture-testing methodologies is that it emulates the loading conditions experienced by dental re

239 ected to lipopolysaccharide challenge, which emulates the macrophage-based innate immune responses ag

240 d H4 at the targeted promoter, a result that emulates the natural repression mechanism of these domai

241 elf-assembly of 'Wang' tiles, a process that emulates the operation of a Turing machine.

242 The reaction emulates the second-end capture step envisioned in model

243 This machine emulates the translational capabilities of the ribosome.

244 l-amino acid mixtures emulating the amino acid composition of fasting human pl

245 A geometric phantom emulating the attenuation and scatter properties of the

246 e simplest approaches for DNA amplification, emulating the bacterial replication machinery, and resem

247 ions in temperature and ionic strength while emulating the crowded cellular milieu.

248 TF binds a contiguous DNA target site - thus emulating the design of ZFP TFs described previously for

249 In contrast, suitable in vitro models emulating the developmental pathways of the two major th

250 e view that a blood-stage vaccine capable of emulating the disease-reducing effect of natural immunit

251 s fasting-induced refeeding of mice, thereby emulating the effect of cannabinoid CB1-receptor inverse

252 nct cations to both RCK domains is additive, emulating the effect of fully occupied Ca(2+) binding si

253 um toward the cytoplasm-facing conformation, emulating the effect of protonation.

254 ructure-function analyses in model membranes emulating the endoplasmic reticulum lipid composition co

255 cal nor enzyme catalysis has been capable of emulating the extraordinary activity and specificity of

256 he morphogenesis as well as key insights for emulating the intricate optical response of the exoskele

257 of the ARM/E-cadherin cytosolic tail complex emulating the most probable stress geometry occurring in

258 Synthetic matrices emulating the physicochemical properties of tissue-speci

259 Simulated nodules emulating the radiographic characteristics of subtle tis

260 s copper that disturbs envelope homeostasis, emulating the role of the CusR/CusS regulatory system pr

261 ART generates simulated sequencing reads by emulating the sequencing process with built-in, technolo

262 We speculate that by emulating the statistical methodology of previous system

263 introduce a de novo peptide topology that-by emulating the virus architecture-assembles into discrete

264 forum for young investigators who aspire to emulate their idols and mentors just as I did in 1969 wh

265 and that exogenous application of force can emulate these cytoskeletal forces and trigger T cell act

266 e to self-antigens provide an opportunity to emulate these processes pharmacologically.

267 Nonnatural foldamers have been developed to emulate these protein structures as well as investigate

268 nt probes have been developed that optically emulate these radionuclides.

269 natural biological channels and the dream of emulating these behaviours in more robust synthetic mate

270 nd emerging computational systems capable of emulating these capacities.

271 Efforts to emulate this complexity via the synthetic control of che

272 We have examined a method to emulate this endogenous mechanism as a means of enhancin

273 Several studies have aimed to emulate this enzymatic site-selectivity with designed tr

274 T (hAGT) from its own promoter (SRA mice) to emulate this expression.

275 To emulate this fundamental process in electronic devices,

276 that realistic bacterial control systems can emulate this optimal strategy for rapid proteome adaptat

277 Attempts to emulate this success with other nuclear hormone ligands

278 A K35L mutation emulates this effect and results in the rapid self-assem

279 Thuja plicata branchlets is described which emulates this efficient water collection behaviour.

280 Emulating this endogenous adaptive response to alpha-syn

281 Emulating this natural design, we fabricate artificial s

282 Our findings emulate those for pDC-reactive opsonophagocytic Ab respo

283 ties in Neuro 2A cells under conditions that emulate those prevalent across endosomes.

284 investigated experimentally with conditions emulating those at Mount Keith Nickel Mine (MKM), Wester

285 hway that tropical LULC change modellers may emulate to further improve the discipline.

286 in proteins containing "WSXWS motifs" can be emulated to stabilize the core of a miniature protein.

287 time mechano-neuro-transduction (MNT), which emulates to some extent the firing dynamics of SA1 cutan

288 Rs indeed curbs dopamine released by stimuli emulating tonic firing, it allows a rapid rise in dopami

289 ry correlation results have been obtained to emulate toxicity in five of the selected aquatic species

290 perspectives and easily alter the layout to emulate traditional textbook representations.

291 Washout of CD40 to emulate transient T-cell contact permitted BCL6 target g

292 to resistive leads, we create a system that emulates tunnelling in a Luttinger liquid, by controllin

293 penes, a sequence that is often difficult to emulate under abiotic conditions.

294 irions from low- and high-risk HPV types can emulate various aspects of HPV virion attachment and inf

295 use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CN

296 olyinosinic-polycytidylic acid [polyI:C]) to emulate viral infection and examined its effect on halot

297 ines, or derived from stem cells, adequately emulates what is believed to occur during human drug-ind

298 tic protein scaffold, a process we sought to emulate with synthetic biomimetic hydrogel polymers.

299 GroEL (K(d) micromolar to nanomolar) may be emulated with a single peptide (AMPH(+)) (apparent K(d)

300 preconditioning, and IPC neuroprotection was emulated with the activator of epsilonPKC.