ライフサイエンスコーパス: enantiomeric excess

1 ields (conversion, diastereomeric ratio, and enantiomeric excess).

2 alkyl substituents in the 2 position (71-97% enantiomeric excess).

3 lds and high enantioselectivities (up to 92% enantiomeric excess).

4 th up to >98% conversion and with up to >98% enantiomeric excess.

5 nantioenriched chiral center without loss of enantiomeric excess.

6 terocyclic products in exceptional yield and enantiomeric excess.

7 iastereoselectivity and in high or very high enantiomeric excess.

8 ned in high yield, diastereomeric ratio, and enantiomeric excess.

9 r of +/-0.08 mM in concentration and 3.6% in enantiomeric excess.

10 ith aniline afforded the urea product in 51% enantiomeric excess.

11 undergo oxidation with complete retention of enantiomeric excess.

12 fording secondary alcohols in high yield and enantiomeric excess.

13 tically useful intermediate with exceptional enantiomeric excess.

14 ted beta-lactones in moderate yield and high enantiomeric excess.

15 ion that affords polycyclic products in high enantiomeric excess.

16 with EtOH to give amide ester (S)-6b in 84% enantiomeric excess.

17 ful chiral building blocks in high yield and enantiomeric excess.

18 tative diastereoselection and high levels of enantiomeric excess.

19 libration is accompanied by complete loss of enantiomeric excess.

20 2-methyl-3-phenylpropanoic acid 14 in >/=95% enantiomeric excess.

21 y on the resolution rate, product yield, and enantiomeric excess.

22 gave the acid in 97% chemical yield and 91% enantiomeric excess.

23 CH-insertion product in 62-69% yield in high enantiomeric excess.

24 hesis of tertiary phosphine oxides with high enantiomeric excess.

25 c cyclopentenones were obtained in up to 75% enantiomeric excess.

26 mations led to the target compound with high enantiomeric excess.

27 yramide 6c yielded the desired (+)-4 in high enantiomeric excess.

28 give the cyclopropyl lactones 17a-d in high enantiomeric excess.

29 and that yields a single regioisomer in high enantiomeric excess.

30 robenzofurans in consistently high yield and enantiomeric excess.

31 in up to 98 % yield and greater than 99.5 % enantiomeric excess.

32 ions, nonanionic conditions, and with a high enantiomeric excess.

33 nd provides the title compounds in excellent enantiomeric excess.

34 oth natural products were obtained in >/=99% enantiomeric excess.

35 btained in high chemical yield and with high enantiomeric excess.

36 ohols, yielding up to 96% conversion and 99% enantiomeric excess.

37 ical yield and 100% diastereoselectivity and enantiomeric excess.

38 d reactivity and generate products with high enantiomeric excess.

39 tuted dehydropiperidinones in high yield and enantiomeric excess.

40 Yields range from 57 to 99% with 78-95% enantiomeric excess.

41 orinated compounds in good yield and in high enantiomeric excess.

42 lution process, which causes a change of the enantiomeric excess.

43 ction of alpha-arylquinolines with up to 90% enantiomeric excess.

44 ns to bicycloalkenes in high yield with high enantiomeric excess.

45 deliver target structures in high yield and enantiomeric excess.

46 thesis of QUINAP and its derivatives in high enantiomeric excess.

47 n of both aldehydes and ketones provided low enantiomeric excesses.

48 product in good to excellent yields and high enantiomeric excesses.

49 bound isomer, appear to be critical for high enantiomeric excesses.

50 s, high diastereomeric ratios, and excellent enantiomeric excesses.

51 ns of carbenes into C-H bonds with up to 98% enantiomeric excess, 35,000 turnovers, and 2550 hours(-1

52 ced in good overall yields (20-54%) and high enantiomeric excess (73-97% ee).

53 to give general access to allenes with high enantiomeric excess (84-95%) for both malonate and amine

54 es, (R)- and (S)-12, in good yields and good enantiomeric excesses (84-94%).

55 ltigram synthesis of the carbocycles in high enantiomeric excess (92% ee).

56 rganic catalyst to assemble products of high enantiomeric excess (a single optical isomer), are also

57 itions (-64% enantiomeric excess versus +89% enantiomeric excess); a transformation from one prevalen

58 e indicator chemistry, cellular imaging, and enantiomeric excess analysis, while also being involved

59 ion of a cyclic enone in excellent yield and enantiomeric excess and a potentially biomimetic oxidati

60 Improved enantiomeric excess and catalase activity as compared to

61 determination of the absolute configuration, enantiomeric excess and concentration of the target comp

62 faces of the enolate of an azlactone in high enantiomeric excess and diastereomeric excess.

63 is often challenging for mixtures with high enantiomeric excess and for complex molecules with stron

64 s a diverse range of propargylamines in high enantiomeric excess and good yield both in water and in

65 ives access to both enantiomers in excellent enantiomeric excess and good yield.

66 o[3,4:1,2][60]fullerenes with high levels of enantiomeric excess and moderate to good conversions.

67 alcohols are cleaved from the resin in high enantiomeric excess and moderate to good overall yield.

68 Soai autocatalytic reaction; accounting for enantiomeric excess and rate observations, that is both

69 ha-disubstituted aldehyde hydrazones in high enantiomeric excess and yield.

70 rmation of the 3R alcohol configuration (99% enantiomeric excess) and contrasted with racemic 1-octen

71 94%) with high enantioselectivity (up to 99% enantiomeric excess) and excellent chemoselectivity.

72 high enantioselectivity (typically 90 to 99% enantiomeric excess), and afford products that are key p

73 nary carbon stereocenters are formed in high enantiomeric excess, and the conditions tolerate a range

74 High yields and enantiomeric excesses are observed for various isochroma

75 ly (microgram concentration) and accurately (enantiomeric excess as low as 0.30% and enantiomeric imp

76 ly (milligram concentration) and accurately (enantiomeric excess as low as 0.6%) determined by use of

77 s with only about 1.5mg/mL concentration and enantiomeric excess as low as 0.80%, in water or in a mi

78 pounds with only microgram concentration and enantiomeric excess as low as 1.5%, in water or in a mix

79 two stereogenic centers are set by DERA with enantiomeric excess at >99.9% and diastereomeric excess

80 kyl groups to benzaldehyde, we have observed enantiomeric excesses between 96% (R) and 75% (S) of 1-p

81 ite furanone derivative was prepared in high enantiomeric excess by an immobilized lipase-catalyzed s

82 itro alcohols in good to excellent yield and enantiomeric excess by borane-dimethyl sulfide in the pr

83 A method for determining enantiomeric excess by mass spectrometry was employed to

84 ketones are prepared in good yield with high enantiomeric excess by rhodium-catalyzed allylic substit

85 Enantiomeric excess calibration curves were made using b

86 Enantiomeric excess calibration curves were made using b

87 molecules and quantitative determination of enantiomeric excess can be achieved in a table-top instr

88 ximately 70% of the variance in the observed enantiomeric excess can be attributed to the steric fiel

89 lized and unfunctionalized olefins with high enantiomeric excesses, demonstrating the potential utili

90 ocess we also explored chirality sensing and enantiomeric excess determinations.

91 Enantiomeric excesses dropped sharply with catalyst load

92 mplification of a spontaneously formed small enantiomeric excess (e.e.).

93 rded a mixtures of trans-(+)-(4S,5R)-4b with enantiomeric excess ee=99% and cis-(-)-(4S,5S)-4a with e

94 ic excess ee=99% and cis-(-)-(4S,5S)-4a with enantiomeric excesses ee=77% and ee=45% respectively.

95 eported in excellent yields (up to >99%) and enantiomeric excess (ee 99%).

96 The mechanism for the high enantiomeric excess (ee) (80-90%) observed in the photoc

97 gh levels of asymmetric induction [up to 89% enantiomeric excess (ee) and 92% ee for the two chiral c

98 ocol for the fast determination of identity, enantiomeric excess (ee) and concentration of chiral 1,2

99 ral approach to high-throughput screening of enantiomeric excess (ee) and concentration was developed

100 ons, the enantioselectivity is enhanced; the enantiomeric excess (ee) becomes as high as 46%.

101 olution of homochirality requires an initial enantiomeric excess (EE) between right and left-handed b

102 Enantiomeric excess (ee) determination is crucial in man

103 We report herein an unprecedentedly high enantiomeric excess (ee) for Pd patches deposited onto C

104 The enantiomeric excess (ee) in the endo-cyclobutanols is me

105 ral solvating agents (CSAs) to determine the enantiomeric excess (ee) of 18 MA samples over a wide ee

106 oncurrent determination of concentration and enantiomeric excess (ee) of a chiral analyte, which has

107 conditions as a means to obtain the highest enantiomeric excess (ee) of a desired transformation.

108 s (eIDAs) were used for the determination of enantiomeric excess (ee) of alpha-amino acids as an alte

109 diastereomeric excess (de) limits the final enantiomeric excess (ee) of any phosphorus products deri

110 Solutions with as little as 1% enantiomeric excess (ee) of D- or L-phenylalanine are am

111 sented chiral assay is able to determine the enantiomeric excess (ee) of D-cysteine in the whole rang

112 Finally, the prediction of enantiomeric excess (ee) of test samples with various al

113 A large L-enantiomeric excess (ee) of the alpha-methyl amino acid

114 s were observed leading to variations in the enantiomeric excess (ee) of the chemisorbed layers with

115 influence the course of a reaction, with the enantiomeric excess (ee) of the product linearly related

116 been exploited for precise quantification of enantiomeric excess (ee) ratio (R/S) up to 99:1 in the p

117 eir chemical characterization and associated enantiomeric excess (ee) values are commonly reported.

118 e for the high-throughput screening (HTS) of enantiomeric excess (ee) values.

119 idine-3-carboxylates from nitriles in 68-90% enantiomeric excess (ee) via allylboration, followed by

120 Enantiomeric excess (ee) was originally defined as a ter

121 th dimethylmalonate can be catalyzed in high enantiomeric excess (ee) with a beta-turn-based ligand.

122 High enantioselectivity (80-92% enantiomeric excess (ee)) has been obtained for the epox

123 from irradiations of (R)-2 retain up to 31% enantiomeric excess (ee), but the ees of the same photop

124 mixtures to be analyzed for as little as 1% enantiomeric excess (ee), by simply recording the ratios

125 ccurately modeled the calibration curves for enantiomeric excess (ee).

126 enantiopurity and the precise measurement of enantiomeric excess (ee).

127 afforded cyclization products at comparable enantiomeric excesses (ee's) and 4-7 times higher cataly

128 istribution, and scope of these amino acids' enantiomeric excesses (ee) have been frustrated by the r

129 The most pristine CRs also revealed natal enantiomeric excesses (ee) of up to 60%, much larger tha

130 sm (FT-VCD) to follow changes in the percent enantiomeric excess (% EE) of chiral molecules in time u

131 t- (left-)handed twisted nanoribbons with an enantiomeric excess exceeding 30%, which is approximatel

132 nantioenriched alpha-branched amines (>/=96% enantiomeric excess) featuring two minimally differentia

133 lucidate the correlation between defects and enantiomeric excess, five characterization techniques (F

134 methylformamide) and observed an increase in enantiomeric excess for 1-phenylethanol of 35% with the

135 Accurate determinations of enantiomeric excess for amino acids and the chiral drug

136 eous determination of percent conversion and enantiomeric excess for each substrate.

137 ure of H(2) caused a significant increase in enantiomeric excess for low catalyst loading reactions.

138 Catalyst 5a, which gave high enantiomeric excesses for certain substrates without the

139 terms of product substrate scope and product enantiomeric excess) for the generation of enantioenrich

140 e conveniently prepared in one step and high enantiomeric excess from propionyl chloride, using a cat

141 nantioselectively, with yields of 21-74% and enantiomeric excesses from 6 to 64% at 50 degrees C.

142 Primary allylic amines with enantiomeric excesses from 97 to >99% were prepared by a

143 c alpha-olefins into chiral products with an enantiomeric excess greater then 90 per cent.

144 proceeds in nearly quantitative yields with enantiomeric excesses greater than 99.7%.

145 ,7'-dihydroxy-8,8'-biquinolyl (1), in modest enantiomeric excess (> or =37%, > or =77% ee).

146 enyl phosphines (1a-h) were prepared in high enantiomeric excess (>95% ee in most cases) by way of an

147 roxyacids in good yield (65-70%) and in high enantiomeric excess (>99%).

148 architecturally complex heterocycles in high enantiomeric excess has been developed.

149 High enantioselectivity (89-93% enantiomeric excess) has been attained for this challeng

150 diastereomers of the Henry adduct with high enantiomeric excess, homochiral at the oxygen-bearing ca

151 sly from reaction mixtures, with an enhanced enantiomeric excess if initially enantioenriched, which

152 d the formation process could also result in enantiomeric excesses if the incident radiation is circu

153 demonstrate in principle how high levels of enantiomeric excess in a mixture of enantiomers can be q

154 measured value for Murchison is the largest enantiomeric excess in any meteorite reported to date, a

155 metric amplification-the development of high enantiomeric excess in biomolecules from a presumably ra

156 tant beta-nitroamines are obtained in 70-94% enantiomeric excess in good yield and can be readily red

157 ed on ion/molecule reactions for determining enantiomeric excess in mixtures of amino acids is illust

158 -methyl-1-hexanols in 88-92% yield in 90-92% enantiomeric excess in one step.

159 of racemic propylene oxide, thus leaving an enantiomeric excess in the solution phase.

160 d summarise recent thoughts on the origin of enantiomeric excess in the universe.

161 ropyl C-H bonds in high yields and with high enantiomeric excesses in the presence of a rhodium catal

162 s lead to stereodifferentiation and, thus to enantiomeric excesses in the products.

163 e presented, which consistently provide high enantiomeric excesses in the range 91-98%.

164 The enantiomeric excess increased to 8 +/- 4%, 27 +/- 1%, an

165 Enantiomeric excess is strikingly insensitive to tempera

166 Improvement of enantiomeric excesses is attained by the use of catalyti

167 Thus, erosion of the enantiomeric excesses is observed for one of the two pro

168 zed asymmetric allylic alkylation yields 92% enantiomeric excess, matching prior solution-phase resul

169 -dependent enantioselectivities, with higher enantiomeric excesses obtained at lower pressures.

170 s largest for erythrose, which may reach a D-enantiomeric excess of >80% with L-Val-L-Val catalyst.

171 On the other hand, the enantiomeric excess of (+)-pinoresinol formed was depend

172 e liquid chromatography purification, a high enantiomeric excess of (18)F-FDOPA ( approximately 97%)

173 n 64% yield as a single diastereomer with an enantiomeric excess of 89%.

174 -1-substituted 1-propanols 10a-n with a mean enantiomeric excess of 92%.

175 overall yield of 55% (three steps) and high enantiomeric excess of 95%.

176 to create a bicyclic enal in one step and an enantiomeric excess of 98%.

177 etermination of enantiomeric purity up to an enantiomeric excess of 99.8%.

178 the enantiomer in the mixture and scale with enantiomeric excess of a component.

179 s a high-throughput method for measuring the enantiomeric excess of allylic acetates.

180 mination of the identity, concentration, and enantiomeric excess of chiral vicinal diols, specificall

181 es and could also significantly increase the enantiomeric excess of direct asymmetric synthesis and c

182 kinetic method, allows rapid quantitation of enantiomeric excess of drug mixtures.

183 organic nanostructures obtained from growing enantiomeric excess of intrinsically chiral NCs or arran

184 Changes in the enantiomeric excess of mixed monolayers of chiral dipept

185 ve linear model was applied to determine the enantiomeric excess of samples of two alcohols without a

186 easurements of both the total amount and the enantiomeric excess of several amino alcohols at micromo

187 of Leu, Pro, and Phe can be deduced from the enantiomeric excess of sublimates, the behavior of the k

188 inkers, impacts on the reaction rate and the enantiomeric excess of the aldol products.

189 The enantiomeric excess of the chiral fatty acids has been m

190 g the QR(fixed) method for determinations of enantiomeric excess of the drug DOPA in the presence of

191 Consequently, the enantiomeric excess of the partial sublimate is dependen

192 The enantiomeric excess of the product was determined by 19F

193 tic amounts of host are able to increase the enantiomeric excess of the products formed.

194 zed with no significant loss in the yield or enantiomeric excess of the products.

195 vided strong evidence that the modulation of enantiomeric excess of the reaction product indeed stems

196 The enantiomeric excess of three different asymmetric cataly

197 opure complex, alcohols are produced with an enantiomeric excess of up to 85% (S) at TOF up to 2000 h

198 lent enantioselectivity is achieved, with an enantiomeric excess of up to 99%.

199 nd seven-membered N-heterocyclic amines with enantiomeric excesses of >90% in many cases and up to 99

200 3-substituted morpholines in good yield and enantiomeric excesses of >95%.

201 ne ethers that are axially chiral, very high enantiomeric excesses of cyclopentenone products are obs

202 cal distribution of d- and l-crystals, large enantiomeric excesses of either d- and l-crystals can be

203 accurately determine the concentrations and enantiomeric excesses of five unknown samples with an av

204 er of substituents in the 4-position, giving enantiomeric excesses of greater than 82%.

205 Enantiomeric excesses of up to 72% (S) and 70% (R) were

206 n of ketones, giving reduction products with enantiomeric excesses of up to 99%.

207 S)-alpha-phenyltryptamine derivative with an enantiomeric excess over 99%.

208 PV reaction does not affect product yield or enantiomeric excess over time.

209 Enantiomeric excesses range from 60-99% for a collection

210 ization of 1,3-meso-diols is successful with enantiomeric excesses ranging from 78 to 85%.

211 In one case, the enantiomeric excess reaches 95:5 er, and the reactions c

212 of 1-Endo with 3 was found to give 2 in high enantiomeric excess, regardless of pressure and at a rat

213 cellent enantiomeric purities (>98% and >96% enantiomeric excess, respectively).

214 ite that provided the amination product with enantiomeric excess similar to the original, more struct

215 decreases the reaction rate, while affording enantiomeric excesses similar to the 1:1 BoxH:Ln case.

216 oin is produced by the variants with greater enantiomeric excess than by wild-type YPDC.

217 complex because it is enantiomer ratio, not enantiomeric excess, that directly reflects relative rat

218 The determination of enantiomeric excess, that is, the relative amount of any

219 into valuable chiral benzylic amines in high enantiomeric excess, thereby producing motifs found in p

220 A protocol for evaluating enantiomeric excess through formation of the gamma-lacto

221 timation of selectivity and determination of enantiomeric excess, through to control of regio- and st

222 and produced R-epoxypropane with comparable enantiomeric excess to AMO purified from the original or

223 e asymmetric reactions also impart increased enantiomeric excess to the final product in comparison w

224 ng asymmetric Doyle-Kirmse reactions with an enantiomeric excess up to 71 %.

225 Enantiomeric excesses up to 83% were obtained in the cas

226 entenols 3a-l in good to excellent yields in enantiomeric excesses up to 99%.

227 izontal lineC bond were hydrogenated in high enantiomeric excess (up to >99% ee).

228 ould be successfully obtained with excellent enantiomeric excess (up to >99% ee).

229 products in very good yield (up to 99%) and enantiomeric excess (up to 93%).

230 iral cyclopentane derivatives with excellent enantiomeric excess (up to 94% ee).

231 ective cyclobutane products with significant enantiomeric excess (up to 95% ee).

232 products in very good yield (up to 90%) and enantiomeric excess (up to 95%).

233 drogenated in high regioselectivity and high enantiomeric excess (up to 98% ee).

234 ing scaffold with high yield (up to 99%) and enantiomeric excess (up to 99%).

235 ng para substituents resulted in the highest enantiomeric excess, up to 88%.

236 MDee for an enzymatic method for determining enantiomeric excess, uses the lipase from Pseudomonas ce

237 ding 1,2-diols were produced in good-to-high enantiomeric excess using 0.45 equiv of H(2)O.

238 is used to develop a method for determining enantiomeric excess using only mass spectrometry.

239 n-time-dependent data for concentrations and enantiomeric excess values for substrates and [1,3] shif

240 Whole cells gave lower enantiomeric excess values for the epoxide and a stereos

241 -polyheterocycles of complex topologies with enantiomeric excess values up to 90%.

242 gh-temperature/low-pressure conditions (-64% enantiomeric excess versus +89% enantiomeric excess); a

243 with up to 99% yield and in greater than 99% enantiomeric excess via dynamic kinetic resolution.

244 The enantiomeric excess was found to be proportional to the

245 For a terminal 1,6-enyne, the incremental enantiomeric excess was found to increase from 4 to 26%

246 yed a critical role in whether an erosion in enantiomeric excess was observed.

247 Diastereomeric ratios >20:1 and up to 99% enantiomeric excesses were observed.

248 r the syn or anti adduct selectively in high enantiomeric excess when an appropriate chiral ligand wa

249 produce the vinyl iodide segment 17 in high enantiomeric excess, which was used in a key B-alkyl Suz

250 ssfully cross-coupled in excellent yield and enantiomeric excess with prior conversion of the pinacol

251 I) complexes generated products in 90 to 99% enantiomeric excess with the use of chiral binaphthol-de

252 ocess led to the expected product (up to 87% enantiomeric excess), with its reuse being possible at l