ライフサイエンスコーパス: enantiopure

1 ks of larger arrays that become increasingly enantiopure.

2 e amines with 2-formylphenylboronic acid and enantiopure 1,1'-bi-2-naphthol.

3 (2-PET = 2-phenylethylthiolate) clusters and enantiopure 1,1'-binaphthyl-2,2'-dithiol (BINAS) was mon

4 The preparation of diastereo- and enantiopure 1,2-amino alcohols is also realized using th

5 the products are useful for the synthesis of enantiopure 1,2-diamine and alpha-amino acid derivatives

6 The synthesis of enantiopure 1,2-diaminobicyclo[2.2.2]octane (DABO, 1) an

7 most convenient methods for the synthesis of enantiopure 1,4,5-trisubstituted 1,2,3-triazoles where t

8 successfully employed for the production of enantiopure 1-(2-bromophenyl)ethan-1-amine, thus enablin

9 alcohols generated during the hydrolysis of enantiopure 1-(4-chlorophenyl)-3-phenylallyl and 3-(4-ch

10 concise synthesis of (+)-swainsonine, and an enantiopure 1-substituted quinolizidine of utility in ta

11 Highly enantiopure (1-aryl)- and (1-naphthyl)-1-ethylamines wer

12 w and known calcimimetic analogues employing enantiopure (1-naphthalen-1-yl)ethylamine as chiral prec

13 5H3]]ZrCl2, (S)-8a and (S)-8b, which have an enantiopure, 1-cyclohexylethyl substituent on the "lower

14 the (c-Hex)(2)B and Ti(IV) "ate" enolates of enantiopure (+)-1a (R = MOM) with (+/-)-5c (R(2) = Me, X

15 al flexibility has been synthesized from the enantiopure (1S,2S)-2-(1-H-imidazol-1-yl)-cyclohexanol.

16 The synthesis of enantiopure 2,2'-bispyrrolidine was easily accomplished

17 by a retro-Michael-type elimination to give enantiopure 2,4,5-trisubstituted piperidines, a structur

18 The synthesis of 14 enantiopure 2,4-syn-Glu analogues 2b-p is accessed by a

19 onality to the distal allene carbon to yield enantiopure 2,5-dihydro-1H-pyrroles, whereas their palla

20 Enantiopure 2-(tributylstannyl)pyrrolidine hydroiodide m

21 vel methodology has been developed to obtain enantiopure 2-C-glycosyl-3-nitrochromenes.

22 I2-promoted beta-elimination, yielded chiral enantiopure 2-C-glycosyl-3-nitrochromenes.

23 '-biaziridine with Grignard reagents affords enantiopure 2-imidazolidinones in a desymmetrizing, casc

24 Enantiopure 2-methyl-3-substituted tetrahydrofurans are

25 of an L-threonine-derived tetramic acid with enantiopure 2-methyloct-(6E)-enoic acids.

26 Protected enantiopure 2-pyrrolylalanine was synthesized for applic

27 , reductive removal of the auxiliary affords enantiopure 2-substituted heterocycles.

28 alkenes with o-hydroxybenzaldehydes afforded enantiopure (2S,3S,4S)-3-bromo-3,4-dihydro-4-hydroxy-3-n

29 A versatile route to enantiopure 3,3-disubstituted oxindoles and 3a-substitut

30 Moreover, virtually enantiopure 3-amino-1,2-diols could be obtained by the s

31 s selectively at the alpha-position to yield enantiopure 3-pyrroline products.

32 dy immunoassays suggest that a vaccine using enantiopure (-)-3'-AmNic hapten imparts superior capacit

33 tion of each compound revealed that only the enantiopure 3R,4R isomer was capable of blocking Stat5 p

34 Enantiopure 4-formyl-beta-lactams were deployed as synth

35 as based on the N-Boc-directed metalation of enantiopure 4-piperidone (-)-11, which was prepared in f

36 l-derived oxazolopiperidone lactams leads to enantiopure 4-substituted-5-aminopentanols, which are us

37 d on-surface coordination is studied for the enantiopure 6,13-dicyano[7]helicene building block.

38 amidite ligands have been developed based on enantiopure 6,6'-dimethylbiphenols with axial chirality.

39 ion-controlled arylation reaction of chiral, enantiopure acyclic alpha-amino aldehydes enabled by a B

40 ) occurred with KR to give the corresponding enantiopure adducts with the expected stereoselectivity.

41 ntly to generate, after demetalation, highly enantiopure advanced synthetic intermediates possessing

42 rom statistical predominance of mixed versus enantiopure aggregates, must be in action during the ear

43 e provided an alternative access to the same enantiopure alcohol previously obtained through lipase-c

44 Catalytic assembly of enantiopure aliphatic amines from abundant and readily a

45 Enantiopure alkaloid mimics are synthesized via high yie

46 single enantiomeric form, the corresponding enantiopure alkylation products could be obtained with a

47 Enantiopure alleno-acetylenic cage (AAC) receptors with

48 I) alkoxide, generated from (S)-5a, with the enantiopure allylic carbonates (R)-9a,b has been develop

49 ed by highly diastereoselective additions of enantiopure allylic indium or tin reagents.

50 The synthesis of six enantiopure alpha,alpha,alpha',alpha'-tetrakis(perfluoro

51 (S)-N-benzyl-N-(alpha-methylbenzyl)amide to enantiopure alpha,beta-unsaturated esters (beta-substitu

52 regioselectively opened to the corresponding enantiopure alpha-amino phosphonates without N-activatio

53 vides a convenient route to the synthesis of enantiopure alpha-aryl-alpha-hydroxy esters.

54 ker reaction for the asymmetric synthesis of enantiopure alpha-arylglycines has been developed.

55 enantioenriched hydroazulenone enolate to an enantiopure alpha-bromocyclopentenone.

56 val of the chiral auxiliary, highly valuable enantiopure alpha-fluorocarboxylic acids and beta-fluoro

57 rmation provides a straightforward access to enantiopure alpha-methyl alpha-arylglycine esters.

58 igram to kilogram scale to provide three key enantiopure alpha-methyl-beta-cyclopropyldihydrocinnamat

59 ,4-diols with 2-formylphenylboronic acid and enantiopure alpha-methylbenzylamine.

60 A new method for the synthesis of enantiopure alpha-substituted piperazines via direct fun

61 bond of the derivative was shown to generate enantiopure amine starting materials without racemizatio

62 chanisms and are converted to diastereo- and enantiopure amines bearing adjacent stereocenters.

63 e, and a catalase leads to the production of enantiopure amines.

64 ent and environmentally benign production of enantiopure amines.

65 ine nanocrystals grown in the presence of an enantiopure amino acid auxiliary, which binds to the fas

66 We have used this new method to obtain enantiopure amino acids that are not readily prepared by

67 In the case of adequately substituted enantiopure amino alcohols, up to 95:5 of diastereoisome

68 Enantiopure amino-acid derived 1H-benzo[e][1,4]diazepin-

69 rates the synthetic utility of the versatile enantiopure aminocyclopentenol building block (-)-4.

70 ise, inexpensive chemoenzymatic synthesis of enantiopure aminocyclopentenols, a Pd(0)-catalyzed subst

71 ed by its application to the synthesis of an enantiopure analogue of the bioactive 2,3,4,4a,5,9b-hexa

72 A series of racemic and enantiopure analogues of CJ-16,264 was designed and synt

73 to the construction of a variety of designed enantiopure analogues of viridicatumtoxin B led to the d

74 crystal structures allows the analysis of 13 enantiopure and 30 racemic crystal structures of 21 (F/C

75 toins under basic conditions gave a range of enantiopure and enantioenriched quaternary alpha-aryl pr

76 e structures with no distinction between the enantiopure and racemic forms.

77 conducted with enantioenriched mixtures both enantiopure and racemic phases are obtained.

78 lar mechanics simulations, are used to study enantiopure and racemic proline clusters formed by elect

79 The development of large scale synthesis of enantiopure and thermally stable (R)- and (S)-BINOL mole

80 -chloromandelic acid, which has at least two enantiopure and three racemic crystal polymorphs, reveal

81 cluding alkyl-substituted, aryl-substituted, enantiopure, and tertiary allenols.

82 is work demonstrates that through the use of enantiopure assembly, its chiral cavity is capable of ca

83 Enantiopure auxiliaries that inhibit crystallization alo

84 and characterization of five racemic and two enantiopure aziridine analogues of PSPP and the evaluati

85 ome of these modified carbohydrates afforded enantiopure aziridines, nitrocyclopropane, and dihydrofu

86 Moreover, C3 symmetric and enantiopure basket 3, containing (S)-alanine groups at t

87 o biological activity and behavior in soils, enantiopure (-)-beflubutamid definitively has the potent

88 The agricultural use of enantiopure (-)-beflubutamid rather than the racemic com

89 Direct access to complex, enantiopure benzylamine architectures using a synergisti

90 three steps from 2-iodo-1-naphthoic acid and enantiopure beta-amino alcohols.

91 tely increased the overall reaction yield of enantiopure beta-arylalanines between 4% and 19% (depend

92 ere subsequently converted in high yields to enantiopure beta-functionalized cysteines suitable for n

93 evelopment of aqueous methods for generating enantiopure beta-hydroxy carbonyl compounds is an import

94 rase that can be used for the preparation of enantiopure beta-Phe and derivatives thereof.

95 Previously unknown, enantiopure, beta-amino ketones were prepared in modest

96 The convergent syntheses utilize an enantiopure biaryl common intermediate, which is formed

97 synthesis of a representative example of the enantiopure biaryl-like CATPHOS class of diphosphines, (

98 Enantiopure bicyclic dioxino, dihydrofuro, and dihydropy

99 Condensation reactions of enantiopure bis-3,4-diazaphospholanes (BDPs) that are fu

100 Reaction of an enantiopure bisdiazaphospholane tetraacyl fluoride with

101 quent application of this methodology to two enantiopure bishomoallylic amines (which were produced v

102 step, an efficient total synthetic route to enantiopure bulgecinine is reported herein.

103 Enantiopure C(1)-symmetric bis(imino)pyridine cobalt chl

104 A new family of air- and moisture-stable enantiopure C,N-palladacycles (PIN-acac complexes) were

105 propylene was carried out in the presence of enantiopure C1-symmetric ansa metallocene, {1,2-(SiMe2)2

106 A series of enantiopure C1-symmetric metallocenes, [(SiMe2)2[eta5-C5

107 The chiral, enantiopure C2 -symmetric silanediol 1 catalyzes enantio

108 The insertion of enantiopure C2-symmetric diphenylethylene carbonate into

109 As an example, enantiopure C7-fluorinated derivatives of the clinical a

110 This mild cyclization can also be applied to enantiopure camphanyldiamine derivatives, and the produc

111 In the presence of enantiopure camphoric acid, the crystallization process

112 Enantiopure carbo[6]helicenyl boronates were synthesized

113 Highly functionalized enantiopure carbocycles and heterocycles were prepared u

114 of insertion; slow addition of the inserting enantiopure carbonate is often required to maximize the

115 e efficient DKR without slow addition of the enantiopure carbonate.

116 icture that, in isolation or in concert with enantiopure catalysts, the "even-handed" approach has mu

117 hout the radical cascade rearrangement of an enantiopure chiral enyne-allene (bearing one stereogenic

118 An enantiopure cis-2,5-disubstituted pyrrolidine building b

119 Using toluene dioxygenase as biocatalyst, enantiopure cis-dihydrodiol and cis-tetrahydrodiol metab

120 For n = 4 and 5, enantiopure clusters of approximately 50 to 100 prolines

121 Preliminary degradation studies using enantiopure Co(salen) catalysts are also reported.

122 achiral rhodium complex of BTA(PPh2) and the enantiopure comonomer BTA Ile as confirmed by various sp

123 CH2NH2 (or (S,S)-Ph2PCH(Ph)CH(Me)NH2 for the enantiopure complex) in THF under a CO atmosphere to pro

124 With the enantiopure complex, alcohols are produced with an enant

125 tivity, in particular when the adsorption of enantiopure compounds is compared with that of racemic m

126 The quest for enantiopure compounds raises the question of which facto

127 Racemates often have lower solubility than enantiopure compounds, and the mixing of enantiomers can

128 analyzing high-resolution complexes with the enantiopure compounds, we determined that both enantiome

129 novel catalysts for use in the synthesis of enantiopure compounds.

130 Enantiopure cryptophane derivatives bearing nine (2, 3)

131 s was achieved in aqueous solution using two enantiopure cryptophanes.

132 mers with two solid phases: a racemic and an enantiopure crystal.

133 chanism generates single-handed columns from enantiopure CTVs and mixtures of right- and left-handed

134 axially chiral lithiated alkoxyallene to an enantiopure cyclic nitrone.

135 Enantiopure cycloheptadienyl sulfones 6 and 7 are diaste

136 , whose role is to serve as the precursor to enantiopure cyclooctadienone 6.

137 enables the conversion of racemic allene to enantiopure cyclopentenone product in a dynamic kinetic

138 Racemic 7-16 and the enantiopure derivative (R)-22 proved to be potent inhibi

139 mented that allows the direct preparation of enantiopure dihydropyranones from the corresponding race

140 ene do not differentiate between racemic and enantiopure dimers and also suggest that the phenyl ring

141 varying molecular weight was grown from the enantiopure ditopic initiator (R)- or (S)-1,1'-binaphthy

142 in which diastereoselective dialkylation of enantiopure ditriflate 10 with oxindole enolates is the

143 rmal C(60) 2-D packing of 1 nm and exists in enantiopure domains.

144 describes the synthesis of 18a and 18b from enantiopure epoxide 2.

145 e its isotactic counterpart synthesized from enantiopure epoxide and catalyst is semicrystalline with

146 onalization (IEG+) strategy that begins with enantiopure epoxides and facilitates the efficient synth

147 Treatment of a range of (enantiopure) epoxides with the sodium salt of diethyl (p

148 ileged scaffolds in medicinal chemistry, but enantiopure examples containing quaternary stereogenic c

149 e of chirality along the whole process is an enantiopure ferrocenyl pyrrolidine catalytic ligand.

150 pressed alcohol dehydrogenases to synthesize enantiopure fluorinated alcohols is shown.

151 A range of unnatural enantiopure fluorinated alpha-amino acids were obtained

152 rmediate, finally yielding (R)-ramatroban in enantiopure form by the formation of the corresponding a

153 ethylamino)methyl groups were synthesized in enantiopure form employing asymmetric cyclopropanation o

154 s the parent tetrol 2-C-methylerythritol, in enantiopure form from (2S,4R)-cis-2-phenyl-4-tert-butyld

155 hesis of an azepane quaternary amino acid in enantiopure form is described.

156 lized, a scalable and practical route to the enantiopure form of this ligand class is described utili

157 blocks, which are difficult to synthesize in enantiopure form using other methods.

158 tion to construct the key tricyclic cores in enantiopure form with correct absolute configurations.

159 heptane-2-carboxylic acid 11 was prepared in enantiopure form, and its catalytic potential in the dir

160 azepanes from lactams, in either racemic or enantiopure form, is presented.

161 e and to substituted cyclopentanes in nearly enantiopure form.

162 o cis- and trans-3-hydroxypipecolic acids in enantiopure form.

163 noboronic acids in their racemic or in their enantiopure form.

164 e (1R,2S)-(-)-norephedrine furnished L-45 in enantiopure form.

165 nes A-C has been accomplished in racemic and enantiopure forms in 11-13 and 12-14 steps, respectively

166 to resolve rac-[(Ir(ppy)(2)Cl)(2)] into its enantiopure forms, homochiral Ir(6)L(4) octahedra where

167 reocontrolled total syntheses of racemic and enantiopure frog alkaloid 205B (1) were accomplished in

168 methodology for the preparation of uniformly enantiopure fully aromatic [5]-, [6]-, and [7]helicenes

169 t and highly efficient synthetic approach to enantiopure functionalized amino acids (FAAs) 1 skeleton

170 cient protocol for the rapid construction of enantiopure furanosyl and pyranosyl nucleoside amino aci

171 be useful substrates for the preparation of enantiopure gamma-lactams and gamma-lactones via N1-C2 b

172 one via stereospecific glycosylation with an enantiopure glycosyl donor followed by separation of the

173 Two-step redox switching in enantiopure helquat system [P-1](2+) right harpoon over

174 This methodology gave access to enantiopure, highly functionalized 5-(trifluoromethyl)py

175 Iodocyclization of sulfinimine-derived enantiopure homoallylic sulfonamides affords trans-2,5-d

176 the highest degree of stereochemical purity, enantiopure homochiral dendritic dipeptides, exhibits th

177 , which successfully led to the formation of enantiopure homokainoids.

178 In the presence of an enantiopure host, these molecules undergo a deracemizati

179 A method of preparing enantiopure hydroxy-gamma-butyrolactones containing mult

180 A family of racemic and enantiopure indium complexes 1-11 bearing bulky chiral d

181 regation occurs via symmetry breaking of the enantiopure intrinsically C2-symmetric monomer brought a

182 Herein, four new fluorinated diastereo- and enantiopure isatin sulfonamide-based potent and selectiv

183 ger monooxygenase enabling the production of enantiopure lactones or esters used in pharmaceutical in

184 e, with a preference toward the formation of enantiopure layers, and a steady-state effect seen after

185 l ligand monomer (BTA(PPh2), 2 mol %) and an enantiopure ligand-free comonomer (ester BTA, 2.5 mol %)

186 approach is applied, in which samples using enantiopure ligands are compared with samples using enan

187 With complexes of enantiopure ligands, perturbation may involve either dyn

188 n of a double-helical superstructure from an enantiopure macrocyclic dimer which adopts two diastereo

189 eridinols are readily crystallized to obtain enantiopure material.

190 eric strain, will dimerize more readily than enantiopure materials and by a mechanism that preferenti

191 Enantiopure Me(2)-CATPHOS is obtained in an operationall

192 hexyl), zirconocene dichlorides that have an enantiopure methylneopentyl substituent on the "upper" c

193 This second-generation total synthesis of enantiopure (+)-minfiensine was accomplished in 6.5% ove

194 eport the development of tunable microporous enantiopure mixed-metal-organic framework (M'MOF) materi

195 by chiral HPLC, giving an easy access to the enantiopure molecular cages of which absolute configurat

196 water can be promising for the synthesis of enantiopure molecules and are also important for the und

197 thodologies for the construction of valuable enantiopure molecules, including various heterocycles.

198 enzoates, we have prepared a range of highly enantiopure mono- and disubstituted alpha-sulfinyl benzo

199 an achiral metal complex and a complementary enantiopure monomer provided a good level of enantioindu

200 Iridium(I)-catalyzed allylation of the enantiopure monoprotected copper(I) alkoxide, generated

201 aboration of l-serine gave the corresponding enantiopure N,N-dibenzyl-protected gamma-amino-alpha,bet

202 been developed via SN2-type ring opening of enantiopure N-activated aziridines with 2-bromoindoles f

203 the use of copper and can be used to prepare enantiopure N-aryl beta-amino alcohols.

204 verse organometallic reagents readily add to enantiopure N-sulfinyl beta-amino Weinreb amides providi

205 Here, we report the discovery of a enantiopure nanocapsule that is formed through the self-

206 a convenient two-step protocol provided the enantiopure natural product in three steps with an overa

207 X-ray structures of both the racemic and the enantiopure natural products 9, 11, and 13 were obtained

208 en applied to the total synthesis of various enantiopure natural products and commercial drugs, reduc

209 An exceptionally hindered class of enantiopure NHC ligands has been developed.

210 acids, thus providing access to a variety of enantiopure nonsteroidal anti-inflammatory drugs and to

211 is the first report of STS inhibition by an enantiopure nonsteroidal compound.

212 addition of potassium dialkyl phosphites to enantiopure O-protected alpha-hydroxy sulfinimine pseudo

213 proven broadly useful for the generation of enantiopure organic intermediates.

214 We show that the enantiopure organoruthenium inhibitor, 9E1, has an IC50

215 ndly and highly efficient route to producing enantiopure organosilicon molecules.

216 improved methodology for the preparation of enantiopure oxabicyclo[3.2.1]octadienes via a stereodive

217 hrough specific isolation of a diastereo and enantiopure oxime, 2-phenylpropanaldehyde oxime, from pr

218 Finally, starting from enantiopure oxiranylpropargylic ester 13, a racemate of

219 nsible for PAHSA biosynthesis, and access to enantiopure PAHSAs will elucidate the role of stereochem

220 Five enantiopure palladacycles containing palladium bonded to

221 oved thermal properties in comparison to the enantiopure parent polymers.

222 ted postsynthetic modification method yields enantiopure peptides anchored inside MOF cavities.

223 Purely synthetic enantiopure phorbol has remained elusive, and biological

224 um complexes, most of which are derived from enantiopure phosphorus ligands, have been employed for t

225 ed benzothiazole, a scalable synthesis of an enantiopure piperazine fragment, and identification of c

226 associated with the economical production of enantiopure planar chiral compounds.

227 Novel enantiopure policyclic nitrogen heterocycles have been o

228 Enantiopure poly-amido-saccharides (PASs) with a defined

229 joined by an alpha-1,2 amide linkage to give enantiopure poly-amido-saccharides (PASs).

230 iopure tetrahydropyridines and deprotection, enantiopure polyhydroxylated piperidines were isolated a

231 A range of enantiopure polyhydroxylated piperidines, including (2R,

232 practical methods that allow isolation of an enantiopure product in high yield.

233 dma ripening in particular enables access to enantiopure products in a reliable way, simply through g

234 Using enantiopure propylene oxide, we synthesized semicrystall

235 d 1,4-benzodiazepine-2,5-diones derived from enantiopure proteinogenic amino acids allows retentive r

236 Novel enantiopure pseudopeptide models containing a central -(

237 ic kinetic resolution to access a variety of enantiopure pyranones, one of which served as a versatil

238 tic activity, has been accomplished using an enantiopure pyrroline N-oxide building block derived fro

239 onstrate how the described catalysis affords enantiopure quaternary lactams that intercept synthetic

240 r achiral peripheral alkyl chains, including enantiopure R and S branched alkyls, "racemic by mixture

241 tiomerically pure form were synthesized from enantiopure (R)- and (S)-Garner's aldehyde, featuring (i

242 f-organization behavior of uracil-conjugated enantiopure (R)- or (S)-1,1'-binaphthyl-2,2'-diol (BINOL

243 A Lewis acid mediated coupling with enantiopure (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-

244 Thus, we introduced the enantiopure (R)-2-methyl-2-isocyano-3-(tritylthio)propan

245 th that of PAM to increase the production of enantiopure (R)-beta-arylalanines from racemic alpha-ary

246 xternal cofactor was necessary to obtain the enantiopure (R)-derivatives.

247 atic asymmetric route for the preparation of enantiopure (R)-ramatroban has been developed for the fi

248 where the sensitivity of crystallized forms (enantiopure/racemic compound/polymorphs) to both conditi

249 nantioselective kinetic resolution (KR) (one enantiopure reactant) if the relative topicity is highly

250 abled separation and identification by using enantiopure reference compounds of eleven racemic TAGs w

251 derived sulfinate or the alpha-alkylation of enantiopure S-chiral alpha-sulfinyl benzoates, we have p

252 ented syntheses, allowing the preparation of enantiopure (S)- and (R)-coniceine in five steps from co

253 deposition of the submonolayer coverages of enantiopure (S)-2-methylbutanoate species that are produ

254 xy)propan-2-ones allowed the recovery of the enantiopure (S)-alcohols in high yields using the alcoho

255 -alpha-amino-beta-nitro-phosphonate 2d gives enantiopure (S)-alpha,beta-diaminophosphonate 3.

256 New fluorous enantiopure (S)-alpha-aminated beta-keto esters were pre

257 hydrolysis of their nitrile groups to afford enantiopure (S)-alpha-arylglycines.

258 the catalytic enantioselective syntheses of enantiopure (S)-econazole and (R)-mirabegron a late-stag

259 it was possible to achieve the synthesis of enantiopure (S)-fluorohydrins at a 0.5 M substrate conce

260 l footedness by a structural modification of enantiopure (S)-proline, which normally creates a (4 x 2

261 Enantiopure (S,S) and (R,R) dimethyl-ethylenedithio-tetr

262 The monoclinic enantiopure salts, containing four independent donors in

263 that the alcohol stereocenter of silylated, enantiopure secondary alcohols can transmit chirality to

264 Coupling of the enantiopure side chain precursor to 7-TES-baccatin III a

265 A short, concise synthesis of enantiopure, side chain-modified alpha-amino acids such

266 Furthermore, an enantiopure silyl enol ether derivative of (S)-1d was pr

267 The highest order Phi(h)(k) consists of enantiopure single-handed columns that are slightly dist

268 y novel organic molecules can be obtained in enantiopure solid form.

269 The enantiopure starting material for the rearrangement step

270 A synthesis of all four enantiopure stereoisomers of the drug was carried out an

271 Enantiopure stereomers of rosaprostol 1, an antiulcer dr

272 ng motifs between some groups of racemic and enantiopure structures, although they show very differen

273 ne-mediated de-aromatizing cyclization of an enantiopure substrate.

274 ion conditions were also found suitable with enantiopure substrates and furnished products without an

275 ve addition of lithiated vinyl sulfoxides to enantiopure sulfinimines provides direct access to a wid

276 ddition of chloromethylphosphonate anions to enantiopure sulfinimines, has been developed for the asy

277 d intramolecular cyclization of a variety of enantiopure sulfinyl dienyl amines provides novel sulfin

278 Second-generation synthetic routes to enantiopure sulfone 21 and aldehyde 24 are described.

279 bonding and strategies for the synthesis of enantiopure sulfoxides.

280 do-saccharides (PAS) are carbohydrate-based, enantiopure synthetic polymers in which sugar repeat uni

281 The synthesis features the use of the enantiopure synthon, prepared in a set of highly stereos

282 determined by chemoenzymatically synthesised enantiopure TAGs with a co-injection method.

283 Enantiopure TBTQ derivatives of this sort are considered

284 Subsequent deprotection of these enantiopure templates gave (-)-ADMJ and (+)-ADANJ as sin

285 An optimized route to enantiopure tetra-carboxylic acid and tetra-carboxamide

286 elective olefinic oxidation of the resultant enantiopure tetrahydropyridines and deprotection, enanti

287 oselective olefinic oxidations of a range of enantiopure tetrahydropyridines as the key step.

288 an expeditious and efficient preparation of enantiopure (thiolan-2-yl)diphenylmethanol (2) featuring

289 The synthesis of enantiopure thiols is of significant interest for indust

290 A variety of important enantiopure thionyl and arylalkyl primary amines were af

291 Enantiopure tosylate precursors for radiolabeling were o

292 Enantiopure trans-2,5-disubstituted trifluoromethylpyrro

293 Asymmetric syntheses of enantiopure trans-3,4-difluoropyrrolidines have been pre

294 as a single stereoisomer (de, ee >99%) from enantiopure trans-disubstituted aziridine.

295 Furthermore, one of the enantiopure trans-spiranes bearing an additional alpha-s

296 at 140 degrees C for 4 h gives a variety of (enantiopure) trans-cyclopropyl sulfones with high diaste

297 ith a wide range of organic azides to afford enantiopure trisubstituted triazoles.

298 e solubility is enhanced) and can synthesize enantiopure Trp analogues substituted at the 4-, 5-, 6-,

299 A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, us

300 enolates can be readily converted into novel enantiopure vinyl triflates, a class of highly versatile