ライフサイエンスコーパス: encapsidate

1 nsmissibility was not a result of failure to encapsidate.

2 KSHV DNA in plasma appeared to be encapsidated.

3 ndomly sampled from the cell or specifically encapsidated.

4 replicated, and finally the progeny RNAs are encapsidated.

5 s are glycosylated in vivo and these are not encapsidated.

6 is a cytoplasmic protein that is only rarely encapsidated.

7 life, and very few polymerase molecules were encapsidated.

8 esting that the viral DNA in breast milk was encapsidated.

9 as the genome is replicated, translated, and encapsidated.

10 These enveloped viruses encapsidate a bisegmented ambisense single-stranded RNA

11 r and minor capsid proteins, L1 and L2, that encapsidate a chromatinized, circular double-stranded DN

12 ity of viral DNA accounts for its ability to encapsidate a large genome.

13 lease-sensitive 3.5-kb pgRNA while the other encapsidated a nuclease-resistant 2.2-kb spliced RNA.

14 st two different populations of capsids: one encapsidated a nuclease-sensitive 3.5-kb pgRNA while the

15 mbly mixture containing nuclear extract also encapsidated a reporter plasmid.

16 Bacteriophage N4 encapsidates a 3500-aa-long DNA-dependent RNA polymerase

17 viridae) is a positive-strand RNA virus that encapsidates a bipartite genome consisting of RNA1 and R

18 itis B virus (HBV) core protein specifically encapsidates a complex of pregenomic RNA (pgRNA) and vir

19 The PIV5-N nucleocapsid ring encapsidates a nuclease resistant 78-nt RNA strand in it

20 However, enzymatic activity of encapsidated A3G does not correlate with the observed li

21 our recently developed Ad-based vector, the encapsidated adenovirus mini-chromosome (EAM) from which

22 nd the ability of the chimeric proviruses to encapsidate an HIV-1-based vector was studied.

23 Cryo-electron microscopy of virions that encapsidated an additional copy of RNA4 revealed that, d

24 has been found to use two protein shells to encapsidate and protect its genome.

25 actions and icosahedral virus capsids, which encapsidate and protect viral genomes and mediate entry

26 APOBEC3DE was encapsidated and capable of deaminating cytosines to ura

27 ive-strand ssRNA viruses, as well as between encapsidated and capsidless RNA viruses.

28 proportion of spliced RNA to pgRNA that are encapsidated and reverse transcribed.

29 RNAs into virions, both the spectrum of RNAs encapsidated and the mechanisms by which they are recrui

30 NA, and the ability of this antigenome to be encapsidated and to function as template for the synthes

31 RNA that does not encode proteins and is not encapsidated, and yet it replicates autonomously and tra

32 Virion-encapsidated APOBEC3G can deaminate cytosine to uracil i

33 sion magnitude correlated with the number of encapsidated aptamer transcripts per virion, with satura

34 port that these RNAs are, like genomic RNAs, encapsidated as dimers.

35 3BC-linked RNA can be encapsidated as efficiently as VPg-linked RNA.

36 Since the Psi(+) mRNA is not encapsidated as well as genomic RNA, it is only present

37 embrane proteins, core proteins, and DNA are encapsidated at normal levels.

38 fic CTS-directed exogenous proteins that are encapsidated before the DNA.

39 Since the minigenome RNA needs to be encapsidated before transcription ensues, it seems that

40 y impacted the stability of the virions that encapsidated BMV RNA2 and RNA3/4.

41 These results show that the encapsidated BMV RNAs reflect a combination of host effe

42 os, approximately 10% of the viral particles encapsidate both HIV-1 and HIV-2 RNAs.

43 We found that core protein dimer bound and encapsidated both the HBV pregenomic RNA and heterologou

44 e other alphaviruses, Aura virus efficiently encapsidates both genomic RNA (11.8 kb) and subgenomic R

45 The nucleocapsid (N) protein of hantaviruses encapsidates both viral genomic and antigenomic RNAs, al

46 The nucleocapsid (N) protein encapsidates both viral genomic RNA (vRNA) and the antig

47 To determine whether viral DNA was encapsidated, breast milk samples were treated with DNAs

48 The hCMV genome does not carry histones when encapsidated but has been proposed to form nucleosomes a

49 s of a closed DNA strand of 6500 nucleotides encapsidated by 2700 copies of a 46-residue coat subunit

50 viruses, the segmented RNA genome of RVFV is encapsidated by a nucleocapsid protein (N).

51 At least some enriched RNAs were encapsidated by genome-defective nucleocapsid mutants.

52 ctivity by XXI prevents the BrdU-labeled DNA encapsidated by HPV16 from reaching the ND10 subnuclear

53 stranded RNA genome of approximately 13.3 kb encapsidated by multiple copies of the nucleoprotein (N)

54 MusPV1 DNA, whether naked or encapsidated by MusPV1 or human papillomavirus 16 (HPV 1

55 of the positive-strand RNA genome helically encapsidated by N protein monomers.

56 stranded negative-sense RNA genomes that are encapsidated by nucleoprotein and other viral proteins t

57 ages consist of a single-stranded DNA genome encapsidated by several thousand copies of a small alpha

58 In this system, an HIV-1-derived genome is encapsidated by SIVmac core particles.

59 teins, with most of the helical nucleocapsid encapsidated by the major coat protein (CP) and a small

60 protein (CP) and a small portion of one end encapsidated by the minor coat protein (CPm).

61 Vesicular stomatitis virus (VSV) genomic RNA encapsidated by the nucleocapsid (N) protein is the temp

62 enome replication consists of the RNA genome encapsidated by the nucleocapsid protein (N protein).

63 ve-sense, single-stranded RNA genome that is encapsidated by the nucleocapsid protein (N) to form a h

64 ve-sense, single-stranded RNA genome that is encapsidated by the nucleocapsid protein (N) to form the

65 The genomes of influenza A virus (FLUAV) are encapsidated by the nucleoprotein and associated with RN

66 Lentiviral genomic RNAs are encapsidated by the viral Gag protein during virion asse

67 segments that form the nairovirus genome are encapsidated by the viral nucleocapsid protein (N) to fo

68 achine comprising the genomic RNA completely encapsidated by the viral nucleocapsid protein and assoc

69 es is the negative-sense genomic RNA tightly encapsidated by the viral nucleocapsid protein.

70 es have a single-stranded RNA genome tightly encapsidated by the viral nucleocapsid protein.

71 WNV repRNAs were efficiently encapsidated by the WNV C/prM/E structural proteins expr

72 r fidelity in vivo, we developed a D17-based encapsidating cell line (ANGIE P) which is designed to e

73 We utilized the previously described ANGIE P encapsidating cell line, which expresses the amphotropic

74 itory activity of APOBEC3G (CEM15), a virion-encapsidated cellular protein that deaminates minus-stra

75 Furthermore, analysis of the encapsidated chimeric RNA species established that the R

76 ed state' probably corresponds to the native encapsidated conformation, and that the 'open state' rep

77 [poly(I-C)] treatment efficiently eliminated encapsidated cytoplasmic HBV replication intermediates w

78 The increase in encapsidated cytoplasmic replication intermediates in HN

79 Encapsidated DI-RNAs were incorporated into virus partic

80 The flexibility of the RCNMV CP to encapsidate different materials, as long as it is within

81 roheads, terminase (gp17 + gp16), and ATP to encapsidate DNA resistant to nuclease.

82 larly permuted, double-stranded virion DNAs, encapsidate DNA through processive series of packaging e

83 viral DNA intermediates indicated that both encapsidated DNA and covalently closed circular DNA (ccc

84 upting the precise force balance between the encapsidated DNA and the capsid proteins crucial for vir

85 induce a long-range phase transition in the encapsidated DNA genome from a hexagonal to a cholesteri

86 In vivo SN digestion of encapsidated DNA gives an intriguing pattern of DNA frag

87 termined how the structure and energy of the encapsidated DNA in phage lambda regulates the mobility

88 clear periphery but does inhibit transfer of encapsidated DNA into the nucleus.

89 pitopes and bromodeoxyuridine (BrdU)-labeled encapsidated DNA is dependent upon gamma-secretase activ

90 s retained within the virions, and (iii) the encapsidated DNA molecule is shorter than the wild-type

91 The presence of encapsidated DNA or the minor capsid protein, L2, did no

92 Thus, I1 is an encapsidated DNA-binding protein required for the latest

93 uctures proposed for the adenovirus core and encapsidated DNA.

94 tion of KSHV Rta increased the production of encapsidated DNase-resistant viral DNA from HH-B2 cells.

95 Encapsidated dsRNA viruses, most of which are nonenvelop

96 tiretroviral cytidine deaminases that can be encapsidated during virus assembly to catalyze C-->U dea

97 nce 180 copies of the same coat protein (CP) encapsidate each of the BMV genomic RNAs.

98 gregation of coadapted genes associated with encapsidating each segment into a different particle.

99 II disrupted the ability of the pgRNA to be encapsidated efficiently.

100 dict the approximate length of the RNA to be encapsidated for the majority of mutant virions, but not

101 While the encapsidated form of the RNA has been extensively studie

102 and their abilities to replicate and become encapsidated, generate Uc- and Ub-containing terminal fr

103 t actively participates in metabolism of the encapsidated genome and carries regulated signals for in

104 particle indicates that large regions of the encapsidated genome are engaged in secondary structure i

105 ort that all 15 genomic segments of the MdBV encapsidated genome exhibited long-term persistence in C

106 ches to profile RNA recombination within the encapsidated genome of a eukaryotic RNA virus, flock hou

107 ographs of ribonucleoprotein (RNP) reveal an encapsidated genome of substantially different organizat

108 resolution, which result in diversity in the encapsidated genome rivaling that due to mismatch mutati

109 ocapsid protein (N) and binding to N protein-encapsidated genome RNA template (N-RNA template).

110 iments by monitoring the levels of total and encapsidated genome.

111 revealed the asymmetric distribution of its encapsidated genome.

112 tion of virus particles, the organization of encapsidated genomes and their role during assembly are

113 Viruses with separately encapsidated genomes could have their genomes introduced

114 l vector cassettes and that the integrity of encapsidated genomes was intact regardless of size.

115 al protein in infected cells and virions and encapsidate genomic RNA species to form an NP-RNA comple

116 While the structure of encapsidated genomic materials has been routinely charac

117 NC protein resulted in virus particles that encapsidated genomic RNA less efficiently and subgenomic

118 he virus nucleoprotein (NP), a protein which encapsidates genomic RNA to form ribonucleoprotein struc

119 Encapsidated GFP and SN can be injected into bacteria an

120 The major encapsidated host RNAs are noncoding RNAs (ncRNAs) and m

121 oney murine leukemia virus (MLV) selectively encapsidates host mY1 and mY3 RNAs.

122 ent centrifugation testing were positive for encapsidated HPyV7 DNA in skin and peripheral blood spec

123 rylation at a serine residue(s), and becomes encapsidated in a monomeric form.

124 This confirms the prediction that SaPI1 is encapsidated in a virion assembled from helper phage-enc

125 monstrate that the purified protein, and VP4 encapsidated in core-like particles, react with GTP and

126 These enzymes become encapsidated in Deltavif HIV-1 virions and in the next r

127 UNG and SMUG were found to be encapsidated in Deltavpr HIV-1 virions but were signific

128 circular single-stranded DNA (ssDNA) genomes encapsidated in double icosahedral particles.

129 RNAs encapsidated in Escherichia coli by capsids of HBcAg 154

130 Both enzymes were encapsidated in HIV-1 and SIV virions and were active ag

131 tically reduced the amount of human APOBEC3G encapsidated in HIV-1 virions but did not prevent encaps

132 st that biologically active Rep proteins are encapsidated in mature progeny AAV particles.

133 d AAV genomes in 293 cells were successfully encapsidated in mature progeny virions that were biologi

134 but DNA strands of only single polarity are encapsidated in mature progeny virions.

135 is tightly associated with membranes, and is encapsidated in mature virions.

136 e interstrand spacing of double-stranded DNA encapsidated in phage lambda capsids.

137 modulated by stable transduction of FR cDNA encapsidated in recombinant adeno-associated virus-2 in

138 replicate by certain phages, are efficiently encapsidated in SaPI-specific small particles composed o

139 an RNA virus, and its three genomic RNAs are encapsidated in separate virions.

140 a large number of viral proteins and RNA are encapsidated in the infectious virions and transduced in

141 we demonstrated that A3F was quantitatively encapsidated in the mature virion core.

142 e mosaic virus (BMV) RNAs (RNA1 to RNA4) are encapsidated in three distinct virions that have differe

143 ompetent subgenomic RNAs, or replicons, were encapsidated in trans by superinfecting polioviruses.

144 ted property of direct repeat deletion, were encapsidated in virions engineered to contain phenotypic

145 s by premature internal termination and that encapsidates in BMV virions.

146 ense RNA molecules, which are believed to be encapsidated into a single viral particle.

147 f the activation-induced deaminase (AID), is encapsidated into assembling virions.

148 found to reduce the amount of pregenomic RNA encapsidated into core particles as a molecular mechanis

149 Pre-P was not encapsidated into DHBV core particles, and the viable st

150 Thus, 7SL RNA that is encapsidated into diverse retroviruses is a key cofactor

151 ll-known function in SRPs, 7SL RNA, which is encapsidated into diverse retroviruses, also participate

152 10-fold reduction in the amount of viral DNA encapsidated into L2-deficient virions.

153 This ribonucleoprotein complex is then encapsidated into nascent viral core particles, where th

154 iral replication, full-length viral RNAs are encapsidated into new virus particles, while spliced RNA

155 nce of siRNA, full-length HIV-1 RNA is still encapsidated into newly assembled viruses.

156 rferes with phage growth, and is efficiently encapsidated into special small phage heads commensurate

157 irus, the resulting chimeric viral RNAs were encapsidated into TCV virions.

158 on particles revealed that the aptamers were encapsidated into the virions released and that the pack

159 assembly process, HIV-1 RNA genomes must be encapsidated into viral complexes to generate infectious

160 ngly, only the smallest of these isoforms is encapsidated into viral core particles.

161 riginally from the cassava genome but now is encapsidated into virions and transmitted as an episome

162 l as a Gag-Pol fusion protein so that Pol is encapsidated into virus particles through Gag assembly d

163 PhageFISH detected both replicating and encapsidated (intracellular and extracellular) phage DNA

164 he Myoviridae T4 ip1(-) phage that lacks the encapsidated IPI* protein normally injected into the hos

165 results identify a mechanism whereby FIV can encapsidate its genomic mRNA in preference to subgenomic

166 rtite, positive-strand RNA insect virus that encapsidates its two genomic RNAs in a single virion.

167 er, there was no evidence for the release of encapsidated KSHV genomes by BC-1 cells, even though n-b

168 al changes associated with transition of the encapsidated lambda-DNA.

169 ome inhibitors increased transduction of AAV encapsidating larger DNA templates to wt levels, suggest

170 he next generation of AAV vectors capable of encapsidating larger pieces of DNA.

171 esting a preferential degradation of virions encapsidating larger-than-wt genomes.

172 BMV mutants with decreased positive charges encapsidated lower amounts of RNA while mutants with inc

173 , most likely due to reduced availability of encapsidated minigenomes for packaging.

174 nside AAV6 or AAV8 capsids do not persist as encapsidated molecules and are more biologically active

175 1 revealed that the dicistronic replicon was encapsidated more efficiently than the monocistronic rep

176 We characterized encapsidated mRNAs containing deletions or truncations o

177 sid may facilitate its development as a drug-encapsidating nanoparticle for anticancer targeted drug

178 Attempts to encapsidate nanoparticles with diameters larger than 17

179 Encapsidated negative-strand viral RNA was detected usin

180 or production of stable virus-like particles encapsidating nonnative RNAs or other cargoes.

181 y denatured viral RNAs and with our study of encapsidated nonviral mRNAs containing inserts of viral

182 otein (HBc) and the negative charge from the encapsidated nucleic acid.

183 m the HBc protein per se, in addition to the encapsidated nucleic acid.

184 ions for morphogenesis and the management of encapsidated nucleic acid.

185 tructure of the CTD and its interaction with encapsidated nucleic acids at various stages of viral ma

186 ai virus P-L polymerase complex binds the NP-encapsidated nucleocapsid (NC) template through a P-NP i

187 from structural studies of oligomerized, RNA-encapsidating nucleoprotein, and cryo-electron microscop

188 to initiate and terminate DNA packaging and encapsidate one genome-length viral DNA.

189 y remarkable specificity in RNA packaging by encapsidating only their genomic RNA while avoiding pack

190 trans-encapsidated particles could be completely neutralized w

191 Moreover, two molecules are encapsidated per viral particle, where they are found as

192 Full protection of encapsidated pgRNA from nuclease was observed for HBcAg

193 valuable insights into the structure of the encapsidated phlebovirus genome.

194 Compared to unencapsidated Pol enzymes, encapsidated Pol appeared to be (i) highly processive, a

195 Our study suggests that the size of the encapsidated polymer cargo is the deciding factor for th

196 ers simultaneously, was performed to measure encapsidated pregenomic RNA (pgRNA) and minus-strand DNA

197 Therefore, a single polymerase monomer is encapsidated, primes DNA synthesis, synthesizes both DNA

198 side polyhedra, suggesting a spontaneous RNA encapsidating process for CPV assembly in vivo.

199 a proof-of-concept and demonstrated that the encapsidated proteins are active in recipient cells.

200 orylated N, was studied for its abilities to encapsidate rabies virus leader RNA and to support trans

201 Ratios of encapsidated readthrough and polyadenylated transcripts

202 ise 3' end of the genome RNA and synthesizes encapsidated replication products in the presence of the

203 Analysis of the encapsidated replicons after four serial passages with V

204 It was also possible to encapsidate reporter plasmids devoid of BPV1 DNA sequenc

205 ncompassing the gag AUG were not efficiently encapsidated, resulting in a low rate of recombination b

206 he phosphoprotein (P), and on its ability to encapsidate RNA and generate templates that can support

207 R143A mutant N protein failed to encapsidate RNA and to support RNA synthesis and suppres

208 with the P protein but was no longer able to encapsidate RNA.

209 eplaced by a protein that does not appear to encapsidate RNA.

210 ion, the N(EF419/420AA) mutant was unable to encapsidate RNA.

211 ion modulated the interaction of CP with the encapsidated RNA and the release of three of the BMV RNA

212 ith the secondary structure proposed for the encapsidated RNA by Schroeder et al., suggesting that, i

213 sufficient to encode the conformation of the encapsidated RNA even in the absence of coat proteins.

214 ging of viral genomes only if the unspliced, encapsidated RNA expressed full-length Gag protein, incl

215 ruction at 15.4-A resolution showed that the encapsidated RNA formed a dodecahedral cage similar to t

216 m RNA associations in the cytoplasm to yield encapsidated RNA homodimers and heterodimers in Hardy-We

217 They suggest a direct role for the encapsidated RNA in assembly in vivo, which is consisten

218 We find that the amount of encapsidated RNA is not linearly correlated with the net

219 ugh interaction of the cargo with the CPMV's encapsidated RNA molecules.

220 Coliphage N4 virion-encapsidated RNA polymerase (vRNAP) is a member of the p

221 Coliphage N4-coded, virion-encapsidated RNA polymerase (vRNAP) is able to bind to a

222 In addition, the level of encapsidated RNA pregenome in mutant I97L was about 5.7-

223 induced by micrococcal nuclease digestion of encapsidated RNA.

224 that contact the SLC, the B-box RNA, and the encapsidated RNA.

225 tic structural changes in the capsid and the encapsidated RNA.

226 d amino acids required for neutralization of encapsidated RNA.

227 on the possible secondary structures for the encapsidated RNA.

228 What roles these interactions play in encapsidating RNA was studied by mutagenesis of the N pr

229 The four encapsidated RNAs of brome mosaic virus (BMV; B1, B2, B3

230 densities, and distinct relative amounts of encapsidated RNAs.

231 cco have distinct relative abundances of the encapsidated RNAs.

232 ble to directly visualize SV40 VP1 pentamers encapsidating short RNA molecules (500mers).

233 VLPs produced by this system encapsidated similar total amounts of RNA as authentic v

234 Geminiviruses encapsidate single-stranded DNA genomes that replicate i

235 The majority of AAV2 genomes persist as encapsidated single-stranded molecules within the nucleu

236 py, which allows direct visualization of the encapsidated single-stranded RNA and coat protein (CP) N

237 l relationships between the protein coat and encapsidated ssDNA genome are also fundamentally differe

238 alternative, i.e., that the structure of the encapsidated STMV RNA might be the same as the in vitro

239 xplore the possible secondary structures for encapsidated STMV RNA.

240 ngle strands, while its close relative LuIII encapsidates strands of both polarities with equal effic

241 nt for the total amounts of RNA produced and encapsidated, suggesting that competition exists between

242 lts demonstrate that 1-CBI is able to damage encapsidated SV40 DNA.

243 We demonstrate that the virion tails encapsidate the 5'-terminal, approximately 650-nt-long,

244 These data indicate that the Ad3 hexon can encapsidate the Ad5 genome, but with less efficiency tha

245 in volume does not provide adequate space to encapsidate the full length HCMV genome at the same pack

246 these limitations, we developed a system to encapsidate the full-length papillomaviral genome into i

247 virus encodes a nucleocapsid protein (NP) to encapsidate the genome and form a ribonucleoprotein comp

248 The paramyxovirus nucleoproteins (NPs) encapsidate the genomic RNA into nucleocapsids, which ar

249 teins present in the cells could efficiently encapsidate the helper virus.

250 des in a highly immunogenic format, and they encapsidate the mRNAs that direct their synthesis, thus

251 ntly blocked in their ability to efficiently encapsidate the replicated genomes.

252 d that HIV-1 Gag polyproteins preferentially encapsidate the RNA from which they were translated (cis

253 h protein that apparently coats but does not encapsidate the viral genome as visualized by atomic for

254 nomic RNA (pgRNA), the mutant preferentially encapsidated the 2.2-kb or shorter species of spliced RN

255 he nucleocapsid protein (NP) of Sendai virus encapsidates the genome RNA, forming a helical nucleocap

256 Rabies virus (RV) nucleoprotein (N) tightly encapsidates the genomic and antigenomic RNA of RV to fo

257 It is not known whether CPm encapsidates the genomic RNA and, if so, which end and w

258 synthesizes the capsid proteins (L1 and L2), encapsidates the HPV-16 genome, and releases virion part

259 e double-stranded RNA virus which separately encapsidates the large and small RNA segments.

260 is a multifunctional viral gene product that encapsidates the RNA genome and also plays some as yet n

261 nt that forms a T = 1 icosahedral shell that encapsidates the segmented dsRNA genome.

262 tein complex in which the nucleoprotein (NP) encapsidates the single-stranded RNA genome.

263 The nucleoprotein (N) encapsidates the three viral genomic RNA segments and pl

264 is an essential multifunctional protein that encapsidates the viral genome and functions as an adapte

265 An ATP-powered DNA translocation machine encapsidates the viral genome in the large dsDNA bacteri

266 viral protein in infected cells and virions, encapsidates the viral genome RNA, and this NP-RNA compl

267 e primary role of the capsid protein (CP) in encapsidating the RNA progeny, experimental evidence on

268 plays a central role in viral replication in encapsidating the three genomic RNA segments to form fun

269 4 revealed that, despite the increase in RNA encapsidated, the capsid structure was minimally changed

270 After one viral genome is encapsidated, the internal pressure signals termination

271 le-stranded RNA viruses have been thought to encapsidate their genomes by gradual co-assembly with ca

272 d that the ability of viruses to selectively encapsidate their genomic NAs can be explained, at least

273 viruses of plants replicate and selectively encapsidate their progeny genomes into stable virions in

274 Here, we demonstrate that APOBEC3G is encapsidated through a direct interaction with the HIV-1

275 As virion-encapsidated TRTIs can predispose virions for inhibition

276 Virions encapsidating two or three genomes (approximately 25% of

277 and cleaved at specific sequences to produce encapsidated-unit genomes.

278 ells, which harbor 50 to 200 viral episomes, encapsidate viral genome and generate infectious bovine

279 CPs are named for their primary function; to encapsidate viral genomic nucleic acids.

280 nsed in HFF by nuclear IFI16 upon release of encapsidated viral DNA into the nucleus, and the viral n

281 HV production, as measured by the release of encapsidated viral DNA.

282 into viral particles at the plasma membrane, encapsidated viral genomes must be exported from the nuc

283 The location of the encapsidated viral genomic RNA was defined by modeling c

284 ractions which enable efficient packaging of encapsidated viral RNA genomes into budding virions.

285 When IFN was added at 4 days postinfection, encapsidated viral RNA pregenomes disappeared from infec

286 P) complexes consisting of nucleoprotein (N)-encapsidated viral RNA.

287 The nucleocapsid (N) protein of hantavirus encapsidates viral genomic and antigenomic RNAs.

288 The nucleocapsid protein of hantaviruses encapsidates viral genomic RNA and associates with trans

289 own that P acts as a chaperone for NP, which encapsidates viral genomic RNA to form the NP-RNA comple

290 irions in vivo, and the levels of translated encapsidated virion RNA are similar to those of wild-typ

291 e region as nonencapsidated viral RNA, while encapsidated virions accumulate at the outer (cytoplasmi

292 vity was proportional to the amount of trans-encapsidated virus produced from the cotransfection.

293 nterestingly, the secondary structure of the encapsidated vRNA was altered; although dimeric vRNA was

294 V replication origin but was too large to be encapsidated was dependent on the presence of AR1 but di

295 sahedral capsid with T=9 quasi-symmetry that encapsidates well-organized double-stranded DNA and vRNA

296 single-stranded negative sense RNA that are encapsidated with the virus-encoded nucleocapsid (N) pro

297 CMV virion is composed of a large DNA genome encapsidated within a nucleocapsid, which is wrapped wit

298 Bacterial, yeast, and mammalian ssRNA encapsidated within HBcAg(183) all function as TLR-7 lig

299 infection, and approximately 700 copies are encapsidated within the virion core.

300 lls less efficiently (within a log) than AAV encapsidating wt size genomes.