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1 e viral genome into empty preformed capsids (encapsidation).
2 ked to translation of viral mRNAs and genome encapsidation.
3 count for all of the observed effects on RNA encapsidation.
4 result in several different outcomes in RNA encapsidation.
5 ix unwinding may be an intrinsic step in RNA encapsidation.
6 ome length in electrostatically driven viral encapsidation.
7 sms of RNA-Gag recognition essential for RNA encapsidation.
8 sumed capsid-interacting site, important for encapsidation.
9 ur translational and splicing functions over encapsidation.
10 one stem-loop is required for efficient RNA encapsidation.
11 production of procapsids that are capable of encapsidation.
12 vides an additional driving force for genome encapsidation.
13 tein/genomic RNA ratio leading to incomplete encapsidation.
14 kaging motor requires prohead RNA for genome encapsidation.
15 ng linker 2 region, was not required for the encapsidation.
16 e function beyond its structural role in RNA encapsidation.
17 in replication is at the stage of viral DNA encapsidation.
18 ng, suggesting that Pol binds to RNA for its encapsidation.
19 function in both genome replication and RNA encapsidation.
20 ation, which in turn are required for genome encapsidation.
21 ion and positively affects HIV-2 genomic RNA encapsidation.
22 regulatory link between RNA replication and encapsidation.
23 (HIV-2) replication and affects genomic RNA encapsidation.
24 -terminal 210 aa are required for genome RNA encapsidation.
25 lication can be limited by the efficiency of encapsidation.
26 ssembly and packaging rely on the process of encapsidation.
27 2C(ATPase), near N252, that are required for encapsidation.
28 wild-type genome are important for efficient encapsidation.
29 core protein translation and pregenomic RNA encapsidation.
30 210 aa are required for efficient genome RNA encapsidation.
31 duced only B capsids, indicating a defect in encapsidation.
32 is that HIV-1 RNA dimers are formed prior to encapsidation.
33 ents affect primarily AAV DNA replication or encapsidation.
34 ncoded proteins involved specifically in DNA encapsidation.
35 ain of the Ad genome that leads to viral DNA encapsidation.
36 ic carboxylate), nor could these sponsor DNA encapsidation.
37 th the L1 52/55-kDa and IVa2 proteins in DNA encapsidation.
38 s viral DNA synthesis but inhibits viral DNA encapsidation.
39 cle, including reverse transcription and RNA encapsidation.
40 that other viral interactions contribute to encapsidation.
41 e capsid subunit (C) are necessary for pgRNA encapsidation.
42 how other cis-acting sequences contribute to encapsidation.
43 A different region is required only for encapsidation.
44 us viral components that contribute to pgRNA encapsidation.
45 ing sequence and region II facilitates pgRNA encapsidation.
46 en the various viral components during pgRNA encapsidation.
47 I may interact with P and/or C for efficient encapsidation.
48 with human APOBEC3G that prevents its virion encapsidation.
49 RNA-Gag interactions necessary for specific encapsidation.
50 rt codon of gag contribute negligibly to FIV encapsidation.
51 ral components in order to function in pgRNA encapsidation.
52 the mechanisms of capsid assembly and genome encapsidation.
53 619 to 624 (region IX), was required for DNA encapsidation.
54 disulfide bonds is essential for initiating encapsidation.
55 in higher-order assemblies during viral DNA encapsidation.
56 t competition exists between all RNAs during encapsidation.
57 ion on RNA-Gag interactions that lead to RNA encapsidation.
58 d an essential amino acid involved in genome encapsidation.
59 that results in the conical core and genome encapsidation.
60 the host-dependent differences in viral RNA encapsidation.
61 t is not directly involved in regulating RNA encapsidation.
62 ficient to account for the difference in RNA encapsidation.
63 y impairing either deaminase activity or its encapsidation.
64 S4B CTD is crucial for efficient JFH1 genome encapsidation.
65 r the RNA undergoes extensive refolding upon encapsidation.
66 th viral RNA and play important roles in RNA encapsidation.
67 important roles both in RNA replication and encapsidation.
68 role in assisting capsid assembly and genome encapsidation.
69 efined role of Rep40-like proteins in genome encapsidation.
70 he critical role played by this motif during encapsidation, a variant of CCMV RNA3 (C3) precisely lac
71 on at serine 170 is required for optimal RNA encapsidation and a full-length positive-strand DNA phen
77 nderstanding of the mechanisms of A3F virion encapsidation and antiviral function and may lead to inn
78 ed to be atypically compact so as to aid its encapsidation and assist the viral assembly process.
79 al functions are known to rely on its virion encapsidation and be suppressed by HIV-1 Vif, which recr
82 e OAS to nanoparticles directs RNA-dependent encapsidation and demonstrates that foreign cargo can be
85 he LTR in SIN lentivectors are competent for encapsidation and integration, we transduced a lentivira
86 oup are thought to be crucial for successful encapsidation and movement of the virus during infection
87 ased CP further participates in viral genome encapsidation and nucleocapsid core formation, followed
88 347-352), and N (320-324, (Ala)(5)) lost RNA encapsidation and oligomerization but still bound with P
89 o 34 were required in addition for efficient encapsidation and production of full-length antigenome.
92 complex nature of virus assembly and genome encapsidation and provide a new model for how the viral
96 of copackaging RNA partners occurs prior to encapsidation and that HIV-2 Gag proteins primarily pack
97 rus capsid expansion is possible without RNA encapsidation and that picornavirus assembly may involve
98 ith human TRIM21 RING, ablated the efficient encapsidation and the late restriction, suggesting that
99 the protease appears to be required for DNA encapsidation and the subsequent maturation steps leadin
100 uired to carry out viral RNA replication and encapsidation and to produce infectious virus in vitro.
103 hered our knowledge of Picornavirales genome encapsidation and will assist further work in the develo
106 itro analyses of gfp vector DNA replication, encapsidation, and cell transduction revealed a surprisi
110 r Gag translation is essential for viral RNA encapsidation, and Gag can package both wild-type and ga
111 contrast, IDR1 is required for stable sigma1 encapsidation, and IDR2 is required for a postuncoating
112 le, such as translation of the viral genome, encapsidation, and movement of the genome between cells.
113 ether RV +RNAs are assorted before or during encapsidation, and the functions of viral proteins durin
114 he mechanistic process of VEEV assembly, RNA encapsidation, and the roles of different capsid-specifi
115 nistic process of nucleocapsid assembly, RNA encapsidation, and the roles of different capsid-specifi
116 some degradation and interference with viral encapsidation are distinct functional properties of Vif.
118 ag and genomic RNA determinants required for encapsidation are well established, but where and when e
119 nctional capsid protein involved in not only encapsidation, as previously described, but also tegumen
122 e mutant of 2C(ATPase) possessed a defect in encapsidation at 37 degrees C and subsequently in uncoat
123 nthesis, gene segment assortment, and genome encapsidation, biochemical mechanisms of virion morphoge
124 a new site in 2C(ATPase) that is involved in encapsidation but also identify a link between encapsida
125 t electrostatics is a major component in RNA encapsidation but was unable to account for all of the o
126 that epsilon interacts with P to facilitate encapsidation, but it is not known how other cis-acting
127 minor capsid component that is required for encapsidation, but not cleavage, of replicated viral DNA
128 rd site permitted particle formation and RNA encapsidation, but the particles were not infectious.
130 (CP), packaging specificity results from RNA encapsidation by CP that has been translated from mRNA p
133 the virus life cycle and provide signals for encapsidation by nucleocapsid protein and the promoters
135 mosaic virus (CMV) showed that despite trans-encapsidation, CMV failed to complement the defective ce
138 different materials, as long as it is within encapsidation constraint, is a critical factor to be con
139 e for the first time linked a cold-sensitive encapsidation defect in 2C(ATPase) (K259A) to a subseque
142 s-acting sequences on pgRNA are required for encapsidation: epsilon, which is near the 5' end of pgRN
144 The unspliced RNA molecules are selected for encapsidation from a pool of many different viral and ce
145 be drawn: (i) the silencing suppression and encapsidation functions of p37 are both required for sys
151 whose RNA replication, gene expression, and encapsidation have been reproduced in the yeast Saccharo
154 Mutagenesis experiments suggest that pgRNA encapsidation hinges on its strong electrostatic interac
155 virus was not sufficient for high levels of encapsidation, implying that other viral interactions co
157 he thermodynamic basis of the pregenomic RNA encapsidation in human Hepatitis B virus in vivo using a
159 ike particles show that the mechanism of RNA encapsidation in negative-strand RNA viruses has many co
160 of the CTD regulates capsid assembly and RNA encapsidation in the cell-free system in a manner simila
161 membrane conduit essential for viral genome encapsidation in the tailless icosahedral membrane-conta
163 a structural RNA switch mechanism for genome encapsidation, in which protein binding sites are seques
165 cells in the presence or absence of the DNA encapsidation inhibitor 2-bromo-5,6-dichloro-1-(beta-d-r
166 n of SIV and the first demonstration of CypA encapsidation into a virus other than human immunodefici
168 imers, multimerization was not essential for encapsidation into HIV-1 virions or antiviral activity.
169 by certain helper phages and their efficient encapsidation into phage-like infectious particles.
172 iviral functions are believed to rely on its encapsidation into virions in an RNA-dependent fashion.
174 ins recognize their cognate nucleic acid for encapsidation into virions through recognition of a spec
183 ution of viral genomic DNA as a precursor to encapsidation, its exact involvement in host shutoff rem
184 enesis in living cells and indicate that the encapsidation machinery does not substantially help coor
185 Alternatively, NS4B's function in HCV genome encapsidation may entail more than its regulation of the
192 el in which recognition of RNA1 and RNA2 for encapsidation occurs sequentially and in distinct cellul
197 ve RNA1-contacting residues severely reduced encapsidation of BMV RNA1 without affecting the encapsid
199 ctrostatics and additional restraints in the encapsidation of BMV RNAs, which could be applicable to
200 ype 1 (HIV-1) virions, and Vif inhibited the encapsidation of both forms of APOBEC3G into HIV particl
203 the core of N (NCORE) prevents illegitimate encapsidation of cellular RNA, the interaction between t
209 tal data has suggested that dimerization and encapsidation of full-length viral RNAs are linked proce
211 secondary envelopment of viral capsids, the encapsidation of HCMV capsids by a lipid bilayer that oc
214 cis-acting sequences required for efficient encapsidation of its pregenomic RNA (pgRNA), epsilon and
215 changes in Vif reduce expression levels and encapsidation of marmoset APOBEC3G, while the changes in
217 Assembly of many RNA viruses entails the encapsidation of multiple genome segments into a single
219 nterovirus morphogenesis, which involves the encapsidation of newly made virion RNA, is a process sti
220 ave previously shown that the specificity of encapsidation of poliovirus and of C-cluster coxsackievi
221 esolution mechanisms that selectively direct encapsidation of predominantly negative-sense progeny ge
225 otides in quasi-helix 2 were critical to the encapsidation of RNA and the production of templates tha
227 show that cAAVs are efficient templates for encapsidation of single-stranded DNA genomes, an observa
228 her genome modifications designed to enhance encapsidation of the chimeric virus genome and to expres
231 cells and in the productive phase to mediate encapsidation of the newly replicated viral genome.
232 in of dengue virus is essential for specific encapsidation of the RNA genome, but little structural i
235 d formation, it is thought to participate in encapsidation of the viral genome and plays a number of
247 es in the nucleus of the infected cell, with encapsidation of viral DNA to form nucleocapsids, and co
250 lication at distinct stages corresponding to encapsidation of viral pregenomic RNA, reverse transcrip
253 ging signal (Psi) bound by Gag during genome encapsidation or, unexpectedly, the Rev response element
254 h whether dimerization is a prerequisite for encapsidation, or conversely, dimerization follows encap
255 nfectious, neither had individual movement-, encapsidation-, or replication-associated genome regions
256 g replication of viral RNA in the absence of encapsidation, packaging, and cellular export of the vir
257 viruses uses a different mechanism of genome encapsidation, perhaps explored early in the evolution o
258 C terminus of 2C(ATPase) that is involved in encapsidation, possibly achieved through interaction wit
259 translation may be specifically selected for encapsidation, possibly explaining the limitation of two
261 Proteins involved in the herpesviral DNA encapsidation process have become promising antiviral ta
271 f the NC complex with a 101-nucleotide 'core encapsidation' segment of the MoMuLV Psi site reveals a
272 lt, for MLV produced in Ro60 knockout cells, encapsidation selectivity from among all cell RNAs was e
273 lated region (5'-UTR) distinct from the core encapsidation sequence eliminated virion incorporation o
274 uence (pal) located at the 3' end of the psi encapsidation signal is critical for human immunodeficie
275 loney Murine Leukemia Virus contains a "core encapsidation signal" that is essential for efficient ge
276 e pairing in the lower stem of the pregenome encapsidation signal, which harbors the core gene initia
280 the selective advantages for viral yield and encapsidation specificity, predicted from previous model
282 g is required for efficient viral RNA (vRNA) encapsidation, suggesting that Gag:vRNA binding might oc
283 f RNA elements that promote dimerization and encapsidation suggests that these processes may be coupl
284 NA replication, late-gene transcription, and encapsidation take place, in the host cell nucleus.
285 changes in viral gene expression, viral RNA encapsidation, the maturation of the virus particle, cel
286 ly proposed link between DNA replication and encapsidation, the total amount of AAV DNA replication c
287 If dimerization was the sole determinant for encapsidation, then spliced viral RNAs might be expected
288 e subjected to replication, translation, and encapsidation, thus contributing to the synchronization
289 ial steps in the virus life cycle are genome encapsidation to form an infective virion and genome exi
290 1 protein with CPm in protoplasts restricted encapsidation to the 5' approximately 630 nucleotides, w
292 detailed studies on capsid assembly and RNA encapsidation under physiological conditions and identif
293 ithin the core following virus entry, during encapsidation/virus assembly, or within the nucleus may
295 Another major source of variation in RNA encapsidation was due to the purification of BMV particl
296 ounted for solely by the 10-fold decrease in encapsidation, we conclude that L2 contributes to at lea
297 EG PV, we showed that genome replication and encapsidation were distinct steps in the multiplication
298 more, scaffolding protein processing and DNA encapsidation were inhibited by 99%, and viral growth wa
299 associates with nuclear capsids prior to DNA encapsidation, whereas both pp150 and pUL96 associate wi
300 HIV-1 replication assay suggests that Vif co-encapsidation with APOBEC3G can promote sublethal mutage
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