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1                                                   Secondary end points included 3-component MACE (myocardial infarction,
2                                                   Secondary end points included 5-year BPFS, overall BPFS, local recurren
3                                               Each of these end points included a prespecified target threshold ranging f
4                                                   Secondary end points included all-cause death, stent thrombosis, myocar
5                                                   Secondary end points included all-cause mortality and all major vascula
6                                                   Secondary end points included angiographic and safety outcomes.
7                                                   Secondary end points included any infection, hospitalization for infect
8                                                   Secondary end points included bleeding complications and new infections
9                                             Other secondary end points included cartilage thickness on quantitative MRI a
10                                                             End points included change from baseline to week 16 in percen
11                                                   Coprimary end points included change from baseline to week 24 in Nasal
12                                                   Secondary end points included change from baseline to week 24 in Sino-N
13                                                       Study end points included changes in markers of systemic inflammati
14                                                   Secondary end points included death and appropriate shocks.
15                                                   Secondary end points included disability worsening confirmed at 3 month
16                                               The secondary end points included drowsiness, unpleasant taste, and stingin
17 onse rate (ORR) at 24 weeks (ORR(Wk24)); secondary efficacy end points included duration of response (DOR), progression-f
18                                                   Secondary end points included duration of response, progression-free su
19                                       Functional phenotypic end points included effects on beating parameters and intrace
20                                               The secondary end points included freedom from symptomatic arrhythmia, the
21                                                   Secondary end points included global cure (GC; CCR without CDI recurren
22                                                  Additional end points included gluten-specific cluster of differentiatio
23                                    Secondary and additional end points included insulin use, the glycated hemoglobin leve
24                                                             End points included LC50 values, and sublethal effects on gro
25                                               Key secondary end points included major response rate (MRR), progression-fr
26                                         Other effectiveness end points included mean IOP and number of medications at 12
27                                                   Secondary end points included noninferiority with respect to the primar
28                                               Key secondary end points included overall (OS) and progression-free surviva
29                                                   Secondary end points included overall survival (OS), intracranial progr
30 ry end point was progression-free survival (PFS); secondary end points included overall survival (OS), response rate, and
31                                                   Secondary end points included overall survival and safety.
32                                                   Secondary end points included platelet reactivity and ischemic outcomes
33                                                   Secondary end points included predisposing factors for treatment respon
34                                                   Secondary end points included procedural complications within 30 days a
35 centrally assessed objective response rate (ORR); secondary end points included progression-free survival (PFS), 6-month
36  primary end point was overall survival (OS), and secondary end points included progression-free survival (PFS), objectiv
37                                                   Secondary end points included progression-free survival (PFS), toxicity
38                                              Other efficacy end points included reductions in the transfusion burden duri
39                The primary end point was pCR, and secondary end points included RFS, OS, and gene expression analyses.
40                                                    Clinical end points included safety and clinical remission (modified M
41                                                  Microbiome end points included SER-287 engraftment (dose species detecte
42                                                   Secondary end points included survival at 90 days with good cerebral pe
43                                                   Secondary end points included the change from baseline in 6-minute walk
44                                    Prespecified exploratory end points included the concentration of mutant huntingtin in
45                                                   Secondary end points included the duration of response, progression-fre
46                                                   Secondary end points included the incidence of culprit vessels with acu
47                                                         Key end points included the time-weighted average change in viral
48                                                   Secondary end points included toxicity, compliance, and surgical morbid
49 point was sustained virologic response (SVR), and secondary end points included uptake of and retention in OAT, change in
50                                                     Primary end points included VTE recurrence, bleeding events, and mort