ライフサイエンスコーパス: end-to-end

1 d hyphal filaments (elongated cells attached end-to-end).

2 ells) to filaments (elongated cells attached end-to-end).

3 rate twofold and by allowing them to anneal end to end.

4 osed of multiple copies of the genome joined end to end.

5 simulates a full response element by packing end-to-end.

6 single molecules or paired molecules linked end-to-end.

7 ts from each of the two subcomplexes, linked end-to-end.

8 of triple-helical protomers that are linked end-to-end.

9 elongated structure with monomers connected end-to-end.

10 ing) that scientists enact in this analysis, end-to-end.

11 shows that these phases are produced by the end-to-end adhesion and consequent stacking of the duple

12 sible neck-to-neck pairs and less reversible end-to-end aggregates.

13 Assembling end-to-end along the actin filament is thereby not suffi

14 ator is the protein tropomyosin, which binds end-to-end along the length of the filament.

15 f functional divalent cations, which induces end-to-end alpha-helices in many conantokins.

16 10) with N(8)Q results in a Mg(2+)-complexed end-to-end alpha-helix, accompanied by attenuation of NM

17 le environment for both building and running end-to-end analysis workflows with automated report gene

18 We performed end-to-end anastomoses five times more rapidly than we p

19 sected and reconstructions were performed by end-to-end anastomoses.

20 Operations included simple and extended end-to-end anastomosis (n = 632), patch angioplasty (n =

21 ger age at time of repair (p < 0.001) and an end-to-end anastomosis technique (p < 0.001) were indepe

22 An end-to-end anastomosis was used in 30 patients.

23 esion with a right hemicolectomy and primary end-to-end anastomosis.

24 nts composed of individual bacteria attached end to end and that two TFP-associated proteins, PilT an

25 oral vessels, the sciatic nerve approximated end-to-end and osteosynthesis was performed using an int

26 an measurement of the extent of vessels from end to end, and (4) vessel caliber (VC), defined as the

27 vivo, intermediate filaments may lengthen by end-to-end annealing and that addition and loss of subun

28 filaments and vimentin filaments lengthen by end-to-end annealing of assembled filaments.

29 d and green segments, which is indicative of end-to-end annealing of red and green filaments.

30 To overcome this challenge, we used end-to-end annealing to generate defects that are direct

31 ated by the opposing actions of severing and end-to-end annealing, and we speculate that this regulat

32 with little or no contribution from filament end-to-end annealing.

33 gthen by joining ends in a process known as "end-to-end annealing." To test if this also occurs for n

34 , suggesting a dynamic cycle of severing and end-to-end-annealing.

35 ShotMAP is an analytically flexible, end-to-end annotation pipeline that can be implemented e

36 form a direct molecular signaling pathway by end-to-end apposition of hemichannels containing one (ho

37 We present an end-to-end approach for processing raw in situ expressio

38 Particles assemble end-to-end, as dictated by capillarity, and align along

39 external force revealed that rupture of the end-to-end assembly occurs by the shearing of the termin

40 sess whether Shs1-capped rods are capable of end to end association either with themselves or with Cd

41 binding free energy and the kinetic rates of end-to-end association and dissociation processes were e

42 rate that loop formation is a consequence of end-to-end association between protein fibrils.

43 nt experiments have demonstrated spontaneous end-to-end association of short duplex DNA fragments int

44 s best modelled in the SCR-16/20 model by an end-to-end association of two SCR-20 domains.

45 the forces, free energy and kinetics of the end-to-end association process.

46 fusion PCR, to detect and analyze chromosome end-to-end associations (telomere fusions) within human

47 ad9 was inactivated, increases in chromosome end-to-end associations and frequency of telomere loss w

48 lso display a higher frequency of chromosome end-to-end associations than do control Hsp70.1/3(+/+) c

49 f telomere repeats (i.e., chromosomes joined end to end at their telomeres or fused together after co

50 in which radial actomyosin fibers are joined end-to-end at spot AJs.

51 ation of the vaquita and fisheries, using an end-to-end Atlantis ecosystem model for the Northern Gul

52 elation between the stacking free energy and end-to-end attraction is discussed as well as possible r

53 ene system of 29c was found to have a gentle end-to-end bend as well as a significant longitudinal tw

54 The usefulness of the T-tube for end-to-end biliary anastomosis to reduce the incidence o

55 llular volume between membranes to allow the end-to-end binding between hemichannels.

56 ng Ca(2+) release, this was very uncommon in end-to-end cell pairs.

57 of both proteins gives information about the end-to-end chain distribution and suggests that chain dy

58 depletion leads to telomere dysfunction with end-to-end chromosomal fusions and premature cellular se

59 of adult animals despite triggering massive end-to-end chromosome fusions across the brain.

60 profound developmental defects and abundant end-to-end chromosome fusions in fifth generation (G(5))

61 rlier studies, depletion of Trf2 resulted in end-to-end chromosome fusions mediated by the C-NHEJ pat

62 End-to-end chromosome fusions that occur in the context

63 shortening and are ultimately recruited into end-to-end chromosome fusions via the non-homologous end

64 es that often typify cancer cells, including end-to-end chromosome fusions, anaphase bridges, aneuplo

65 lomeric and subtelomeric DNA, high levels of end-to-end chromosome fusions, increased G-overhang sign

66 Most ALT strains displayed end-to-end chromosome fusions, suggesting that critical

67 ssion of ATM activation and the formation of end-to-end chromosome fusions.

68 instead of ferromagnetic layer realizes the "end to end" circulation of storage data, which remains a

69 e optical reporters employed experimentally, end-to-end collision dynamics exhibit little length depe

70 xperiment and simulation to characterize the end-to-end collision dynamics of unstructured, single-st

71 Finally, we have found that the end-to-end collision rate also depends linearly on solve

72 For longer constructs, however, the end-to-end collision rate exhibits a power-law relations

73 onger dependencies observed for the rates of end-to-end collisions in single-stranded DNA and through

74 e aorta-aorta and porto-cava anastomoses and end-to-end colorectal anastomosis.

75 strand annealing (SSA) reaction to generate end-to-end concatemers of the phage genome for packaging

76 infected by adenovirus E4 mutants accumulate end-to-end concatemers of the viral genome that are asse

77 tion of filaments of bacteria lined up in an end-to-end conformation.

78 integrity of the heart is maintained by the end-to-end connection between the myocytes called the in

79 to form filaments due to a complete lack of end-to-end connections essential for gliding motility.

80 Our end-to-end contact formation measurements reveal that in

81 Theoretical calculations of nucleic acid end-to-end contact probabilities are used to estimate th

82 ls aligning with each other and signaling by end-to-end contact to coordinate the process of differen

83 be transiently "stimulated" if brought into end-to-end contact with tgl+ donor cells.

84 ed (haplotype-resolved) genome sequence with end-to-end contiguity for each chromosome at reasonable

85 Furthermore, we find that this end-to-end cooperativity is determined by the UTR sequen

86 They possess an unusual end-to-end cyclic backbone combined with a cystine knot

87 cular ligation or intramolecular ligation in end-to-end cyclization.

88 Their end-to-end cyclized backbone that enhances molecular sta

89 oRata is an open-source software package for end-to-end data analysis in a wide variety of community

90 OpenCyto supports end-to-end data analysis that is robust and reproducible

91 elf-immolative polymers, which degrade by an end-to-end depolymerization mechanism in response to the

92 The end-to-end diffusion coefficients obtained from the diff

93 A are sufficient to discriminate between the end-to-end dimer and double-helix structures of gramicid

94 loride, indicating a decrease in the average end-to-end distance (collapse) at low denaturant concent

95 orylation at threonine or serine extends the end-to-end distance and increases the effective persiste

96 riments probing backbone structure by IR and end-to-end distance by FRET.

97 applied to the RNA varied in response to the end-to-end distance change of the tether, the RNA hopped

98 ges in the FRET efficiency and hence the DNA end-to-end distance changes are small when the duplex pr

99 domain, were measured in an analysis of the end-to-end distance changes in the RTX domain.

100 In the initial stages, the mean end-to-end distance decreases nearly continuously, and t

101 find that the contour-length scaling of mean end-to-end distance deviates from predictions of a purel

102 nce of an NCp7-induced increase in the 3'-5' end-to-end distance distribution and a partially melted

103 rods by fitting an empirical function on the end-to-end distance distribution curve obtained by MD si

104 he protein on nucleic acid base pairing, the end-to-end distance distribution for the nucleic acid an

105 data analysis method to directly measure the end-to-end distance distribution of a phosphorylatable p

106 By monitoring the end-to-end distance distribution of these segments as a

107 End-to-end distance distributions and correlation times

108 nmonotonic dependence on the variance of the end-to-end distance distributions.

109 s rationalized by calculation of the polymer end-to-end distance dynamics from a Rouse model that inc

110 y stretching, can be an equal contributor to end-to-end distance fluctuations for 35-bp DNA and contr

111 Recent measurements of the distribution of end-to-end distance in short DNA molecules infer coopera

112 t the diffusion coefficient of the protein's end-to-end distance is on the order of 10(8) nm(2)/s, is

113 obal persistence length changes derived from end-to-end distance measurements, and with results of DN

114 f 0.6 x 10(-8) cm2/s (elongated coil with an end-to-end distance of 1.27 microm) to a value of 1.7 x

115 accurate data for the persistence length and end-to-end distance of 107 DNA tethers in a single exper

116 P model, for example, we predict an expected end-to-end distance of about 14 unpaired bases.

117 es to form a highly kinked dimer spanning an end-to-end distance of approximately 100 A.

118 opt a highly kinked organization spanning an end-to-end distance of approximately 140 A.

119 However, the end-to-end distance of CGRP is larger than that of IAPP.

120 After the end-to-end distance of each unfolding geometry was measu

121 In this paper, we present the end-to-end distance of randomly self-paired polymers (RS

122 hich is approximated by the root-mean-square end-to-end distance of the hydrophilic block of the bloc

123 econdary structure of CGRP, we find that the end-to-end distance of the peptide increases with decrea

124 We have also found that the expected end-to-end distance of the RSPP scales roughly as the 1/

125 We discovered that as the end-to-end distance of the target dsDNA molecule is incr

126 ium free energy profiles as functions of the end-to-end distance of the two proteins show that, at va

127 ss the membrane thickness; and 3), the axial end-to-end distance or the applied axial point force.

128 In addition, the scaling of the end-to-end distance R N as a function of the chain lengt

129 of photoswitch undergoes an ~10 A change in end-to-end distance upon isomerization and can be used t

130 e number of basepairs and the scaling of the end-to-end distance with the curvilinear distance, the b

131 y is a function of the loop length, the loop end-to-end distance, and the ion (Na(+) and Mg(2+) in th

132 h, the pH-dependent expansion factor for the end-to-end distance, and the titration behavior of the G

133 properties of mean-square spatial distance, end-to-end distance, contact probability and their chrom

134 istances comparable to the mean free polymer end-to-end distance.

135 measured by the relative fluctuations in the end-to-end distance; rather, it provides a 16 A extensio

136 duplex DNA causes a marked reduction in the 'end-to-end' distance of the DNA in a concentration-depen

137 DNA end-to-end distances and local DNA bend angle distributi

138 sed internal structure, these ensembles have end-to-end distances and mean radii of gyration that agr

139 such that the edge lengths are given by the end-to-end distances between nodes.

140 o nonlinear geometries, and the experimental end-to-end distances for these complexes match those fro

141 foldamers with >10 Aib residues, which have end-to-end distances greater than the hydrophobic width

142 r-FRET-based analyses of the distribution of end-to-end distances in the bent DNA-protein complexes f

143 The shortening of DNA end-to-end distances is indicative of DNA bending in the

144 ymer models for PEVK, we determined the mean end-to-end distances of an 11- and a 21-residue syntheti

145 ss of the membrane increases with increasing end-to-end distances of spectrins, but has a nonmonotoni

146 to probe the distribution of intramolecular end-to-end distances, under a range of conditions.

147 term based on restraints derived from linker end-to-end distances.

148 rentially populates conformations with short end-to-end distances.

149 to the application of Gaussian polymer chain end-to-end distribution to extract Rg from the FRET effi

150 The results can be explained using end-to-end distributions from a wormlike chain model in

151 DNA bending in structures not constrained by end-to-end DNA lattice interactions and that lattice con

152 nnect the cytoplasm of adjacent cells by the end-to-end docking of two Cx hemichannels.

153 We used an end-to-end ecosystem model (Atlantis), forced by downsca

154 By monitoring the end-to-end extension of a mechanically stretched, superc

155 Single-molecule studies probing the end-to-end extension of long DNAs have established that

156 ompaction is evidenced by a reduction in the end-to-end extension of nanomanipulated DNA.

157 In this study we report measurements of the end-to-end extension of poly(U) RNA under 0.1 to 10 pN a

158 low forces while maintaining a predetermined end-to-end extension of the DNA.

159 tions of up to 240 Hz were obtained, and the end-to-end extension of up to 1,000 individual dsDNA enz

160 res additional coordinates orthogonal to the end-to-end extension to be uniquely identified.

161 s in total compaction of the DNA (i.e., zero end-to-end extension).

162 on in which the two proteins associate in an end-to-end fashion in a manner that does not involve an

163 dicate that the two proteins associate in an end-to-end fashion in solution.

164 ally transplanted into Lewis rat abdomens in end-to-end fashion.

165 s clustering to be integrated as a module in end-to-end feature learning pipelines.

166 4.5, the fibrils elongate very slowly via an end-to-end fibril-fibril aggregation mechanism, without

167 evidenced by gel-shift assays and by recent end-to-end fluorescence energy transfer distance measure

168 We found the end-to-end force to be short range, attractive, hydropho

169 distinct unfolding pathways when subject to end-to-end force, one of which is consistent with a prop

170 It is designed to connect miRNA molecules end to end, forming a DNA-RNA duplex through a complemen

171 We programmatically created an end-to-end framework that systematically evaluates warfa

172 of skin lesions using a single CNN, trained end-to-end from images directly, using only pixels and d

173 Telomeres protect chromosome ends from end-to-end fusion and degradation.

174 ila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-as

175 of eukaryotic chromosomes from degradation, end-to-end fusion events, and from engaging the DNA dama

176 End-to-end fusion of critically shortened telomeres in h

177 The biosensor is composed of an end-to-end fusion of cyan fluorescent protein (CFP), chi

178 The end-to-end fusion of DNA methyltransferases to zinc fing

179 CuIn(1-x)Ga(x)S2 (CIGS) nanocrystals, causes end-to-end fusion of nanorod pairs into nanodumbbells at

180 ially resulting in chromosome recombination, end-to-end fusion, and recognition as damaged DNA.

181 DNA-PKcs(-/-) cells and tissues, chromosomal end-to-end fusions and anaphase bridges were readily evi

182 leoprotein complexes that prevent chromosome end-to-end fusions and control cell ageing.

183 an help protect telomeres against chromosome end-to-end fusions and genomic instability.

184 es, and ligase 4 (LIG4)-dependent chromosome end-to-end fusions are markedly reduced.

185 telomere dysfunction-induced foci (TIFs) and end-to-end fusions in ALT-positive cells.

186 To test this hypothesis, we examined end-to-end fusions isolated from Caenorhabditis elegans

187 eficiency leads to an increase in chromosome end-to-end fusions or chromosome ends without detectable

188 G overhang and elevated number of chromosome end-to-end fusions that initiate an ATR-dependent DNA da

189 errations were detected, including telomeric end-to-end fusions, a signature of telomere dysfunction.

190 ed process may create duplications that seal end-to-end fusions, in the absence of breakage-fusion-br

191 Depletion of TRF2 causes chromosome end-to-end fusions, initiating genomic instability that

192 R5, and is sufficient to suppress chromosome end-to-end fusions.

193 horter than average and religate to generate end-to-end fusions.

194 arbored extended G-overhangs, and engaged in end-to-end fusions.

195 it increased G overhangs, recombination, and end-to-end fusions.

196 fibroblasts leads to an increase in telomere end-to-end fusions.

197 tion of chromosome ends from degradation and end-to-end fusions.

198 mote the formation of deleterious chromosome end-to-end fusions.

199 which altered TRF2 protein levels can induce end-to-end fusions.

200 mulation of H3K9me3 at damaged telomeres and end-to-end fusions.

201 Here we use long-read sequencing to generate end-to-end genome assemblies for 12 strains representing

202 c connective tissue that exhibits a striking end-to-end gradient in mechanical properties and thus pr

203 crom) filament bundles assembled together by end-to-end grafting of shorter modules.

204 End-to-end helical distances and duplex flexibility were

205 E2 forms end-to-end homodimers with a conserved C-terminal motif

206 in proteins, the domains almost always occur end-to-end, i.e., one domain follows the C-terminal end

207 th are able to self-assemble side by side or end to end in nonsolvents for the central or terminal se

208 The C-terminal cystine knot domain dimerizes end-to-end in a manner predicted by homology to TGF-beta

209 rapped DNA strands that are closely arranged end-to-end in a single layer along the CNT.

210 Furthermore, sisters separate end-to-end in sequential discontinuous pulses, each elon

211 come from using deep neural networks trained end-to-end in tasks such as object recognition, video ga

212 ngated molecule, with the two SLPs arranged 'end-to-end' interacting with each other through a small

213 s discussed as well as possible roles of the end-to-end interaction in biological and nanotechnologic

214 lay between shape anisotropy-induced and DNA end-to-end interaction-induced N ordering for 11, 24, an

215 ssembly of nanoparticles on 2D platforms via end-to-end interactions and in designing optimally packe

216 st to the behavior of 24 and 48 bp sDNA, the end-to-end interactions between 11 bp sDNA rods with 2-T

217 a reduced inhibition, probably due to weaker end-to-end interactions making it easier for myosin to d

218 ecular dynamic simulations, we characterized end-to-end interactions of duplex DNA, quantitatively de

219 d oligo-thymine (T) overhangs modulating the end-to-end interactions.

220 The end-to-end "interposition" technique and end-to-side "pi

221 a pair of LTRs that have become incorporated end to end into the CaMV genome.

222 al peptide-wrapped SWNTs, possibly connected end-to-end into long fibrillar structures, using an amph

223 on and subsequent wrongful recombination and end-to-end joining during cell division.

224 cal apo-peptide with a flexible center to an end-to-end K2hPg-bound alpha-helix.

225 was calculated from measurements of filament end-to-end length and contour length.

226 The variance in end-to-end length follows a quadratic dependence on the

227 engths, we measured the mean and variance of end-to-end length for a series of DNA double helices in

228 ds (4.0 +/- 0.2 Angstrom) is longer than the end-to-end length obtained from the crystal structure (3

229 subsequently used this method to measure the end-to-end length of a 122-basepair double-stranded DNA

230 ding (53 Angstrom), which is longer than the end-to-end length of the protein obtained from NMR spect

231 athways along a well defined coordinate, the end-to-end length of the protein.

232 irst, we are able to precisely determine the end-to-end length of the transition state before unfoldi

233 chain, whereas crystallography measures the end-to-end length within the "frozen" protein structure.

234 o a broad distribution of rupture forces and end-to-end lengths in the force-extension mode and multi

235 cyclic peptides, first through an orthogonal end-to-end ligation and then a chemoselective ligation w

236 ever, the persistence length surrounding the end-to-end linkage is almost twofold higher for smooth c

237 n amphiphilic triblock copolymer composed of end-to-end linkage of poly(lactic-co-glycolic-acid) (PLG

238 a biodegradable triblock polymer composed of end-to-end linkages between poly(lactic-coglycolic acid)

239 n filaments reveal the azimuthal position of end-to-end linked tropomyosin molecules on the surface o

240 jugated macrocycles that are formed from the end-to-end linking of stilbenes.

241 Adding just a few residues, to convert an end-to-end loop to an internal loop, sharply decreases t

242 s have explored the kinetics of formation of end-to-end loops in polypeptide chains; however, protein

243 h, interior loops will form more slowly than end-to-end loops, owing to the additional excluded volum

244 C to SL-D' and SLC' to SL-D) and stack in an end-to-end manner (SL-C to SL-D and SL-C' to SL-D') that

245 on DNA sequences to predict enhancers in an end-to-end manner by using a deep convolutional neural n

246 As temperature rose, the end-to-end NOEs rapidly disappeared, while the amide sid

247 l field stimulation actively propagated from end to end of antral muscle strips with a constant laten

248 xes which are needed to keep the cells in an end-to-end orientation, leading to separation of daughte

249 f 1D nanocrystal alignment (side-by-side and end-to-end), orientation (horizontal and vertical) and o

250 Finally, we observed regular end-to-end oscillation over very short distances along t

251 lts as web reports in just a few hours->600% end-to-end performance improvement over state of the art

252 troduction accessions was evaluated using an end-to-end phenotyping workflow.

253 This end-to-end pipeline is the first protocol for ChIP-seq i

254 rigami concept, we have developed a scalable end-to-end planning and fabrication process.

255 The tropomyosin family of proteins form end-to-end polymers along the actin filament.

256 l structures of NDEL1, as well as chain-like end-to-end polymers.

257 s more a mixture of varying-length chains of end-to-end polymers.

258 mically to achieve optimal configuration and end-to-end positioning and ligation.

259 Our results indicate that strong end-to-end protein interactions and weak interactions be

260 ely 22 kcal/mol higher than DeltaH++ for the end-to-end proton transfer between the 2-propenyl cation

261 transfer reactions were found for 10 of the "end-to-end" proton transfers.

262 y from high-dimensional sensory inputs using end-to-end reinforcement learning.

263 luding 172 hepaticojejunostomies (98%) and 3 end-to-end repairs.

264 ructure), Forster resonance energy transfer (end-to-end rigidity), molecular dynamics simulation (str

265 Remarkably, it showed exceptional end-to-end sequence identity to the gene cluster respons

266 Technical advances have now made an end-to-end single-use manufacturing facility possible, b

267 t creates a foundation for development of an end-to-end solution for MPS-based experiments or clinica

268 a comprehensive pipeline, which provides an end-to-end solution for novel peptide detection with the

269 lobSTR's implementation is an end-to-end solution.

270 ializing technologies as part of integrated, end-to-end solutions that accelerate neuroscientific dis

271 for alignment stages, and up to a 4.56-fold end-to-end speedup over multithreaded NCBI BLAST.

272 for alignment stages, and up to a 1.75-fold end-to-end speedup over single-threaded NCBI BLAST.

273 tprinting revealed the formation of a unique end-to-end stacked G-quadruplex structure from this sequ

274 a et al. reported on the discovery of strong end-to-end stacking interactions between short DNAs (sDN

275 ions, indicating the onset of some degree of end-to-end stacking interactions.

276 much faster way of unfolding a protein than end-to-end stretching, especially in a low-force regime,

277 Here we report the first end-to-end study of time-lapse V S imaging that uses tra

278 wo CRD palmitoleoyl-binding grooves oriented end to end, suggesting that the Wnt palmitoleoyl group s

279 LF/DNA ligase IV NHEJ ligation complex, that end-to-end synapsis involves a dynamic positioning of th

280 Continuous end-to-end synthesis in the refrigerator-sized [1.0 mete

281 neuploid with double-stranded DNA breaks and end-to-end telomere fusions and most were tetraploid or

282 Notably, the number of end-to-end telomere fusions induced by MT-hTer-47A treat

283 r the first time the mechanism by which such end-to-end template jumps can occur.

284 between RNA templates have similarity to the end-to-end template jumps described for the RNA-directed

285 added to the input mutant RNA3 3' UTR due to end-to-end template switching by BMV replicase during (-

286 conditions, the Cdc11-capped rods polymerize end to end to form long paired filaments, whereas Shs1-c

287 The nanotubes can then join end to end to form stable connections, with unconnected

288 -helical coiled-coil protein that associates end-to-end to form a continuous strand along actin filam

289 At low ionic strength, rods assemble end-to-end to form filaments but not when Cdc11 is absen

290 dc10-Cdc10-Cdc3-Cdc12-Cdc11) that associates end-to-end to form filaments.

291 End-to-end trained deep learning networks consistently o

292 peropyrene adopts a twisted backbone with an end-to-end twist angle of 28 degrees that was unambiguou

293 crowded carbazole that exhibits an 81 degree end-to-end twist but is not resolvable.

294 Compound 2 has an end-to-end twist of 144 degrees , and the two crystallog

295 n studied extensively, we do not yet have an end-to-end understanding of chemotaxis.

296 RI can enhance the responsiveness to dynamic end-to-end user demands and globally optimize radio freq

297 hat the pulling direction coincides with the end-to-end vector of the molecule fragment being stretch

298 hort DNA duplexes to spontaneously aggregate end-to-end when axially aligned in a small volume of mon

299 ires and coupling of fully formed nanowires "end-to-end", with negligible termination and initiation.

300 om others or optimize their strategies in an end-to-end workflow.