ライフサイエンスコーパス: endeavor

1 the phase III randomized, multicenter trial ENDEAVOR.

2 trumentation and approaches facilitates this endeavor.

3 ic strategies for IPF is an important future endeavor.

4 stainable solvents is therefore an important endeavor.

5 in diagnostic procedures to facilitate this endeavor.

6 ration of novelty is central to any creative endeavor.

7 model, making correction a relatively simple endeavor.

8 or react is often the missing piece in this endeavor.

9 btaining their monomers has proved a complex endeavor.

10 We undertook such an endeavor.

11 colipids in lipid membranes is a challenging endeavor.

12 es and personnel available to devote to this endeavor.

13 e ACR should continue this vital educational endeavor.

14 sis environments are ideally suited for such endeavor.

15 e sparing HSC is an attractive but difficult endeavor.

16 ences, despite considerable interest in this endeavor.

17 ther countries and regions embarking on this endeavor.

18 comparative genomics can contribute to this endeavor.

19 logy adds further momentum to this important endeavor.

20 ibutions as professionals in their fields of endeavor.

21 genome is a first and essential step in this endeavor.

22 understood, and targeting HIF is a difficult endeavor.

23 d a powerful context for undertaking such an endeavor.

24 end-of-life care in the ICU is an important endeavor.

25 merging technologies helping to advance this endeavor.

26 cell remains an important bottleneck in this endeavor.

27 atural life remains a remarkably challenging endeavor.

28 atment of malaria and cancer is an important endeavor.

29 biosimilar LMWH has become an active global endeavor.

30 rve as the critical foundation of a research endeavor.

31 ecules, or cancer cells remains a formidable endeavor.

32 judgment, a costly and generally ineffective endeavor.

33 ac surgical patient is a complex and dynamic endeavor.

34 ity and precision has been paramount in this endeavor.

35 1,3-allylic-type strain) is central to this endeavor.

36 ctivate HER3 function has been a challenging endeavor.

37 ive synthesis of such structures is a useful endeavor.

38 d phylogeny can inform a variety of research endeavors.

39 to markedly expedite most strain-engineering endeavors.

40 roaches that we employ in our other research endeavors.

41 al drug design and in other biotechnological endeavors.

42 ctive olefin metathesis in general synthetic endeavors.

43 and social ramifications of their scientific endeavors.

44 to other genomic data collection and sharing endeavors.

45 thesis, drug discovery, and chemical biology endeavors.

46 ata will be critical to the success of those endeavors.

47 ll individual samples to large collaborative endeavors.

48 re reliable and valuable for future research endeavors.

49 it, have created a paradigm for driving such endeavors.

50 clusive platform for focused cancer genomics endeavors.

51 pping, and in marker-assisted wheat breeding endeavors.

52 years, incorporated into quality improvement endeavors.

53 ential to affect a broad range of biological endeavors.

54 ve useful in future structural determination endeavors.

55 logist, and to review the outcomes from past endeavors.

56 on of olefin metathesis in general synthetic endeavors.

57 entify targets for future genome-engineering endeavors.

58 hieve animal welfare and quality of research endeavors.

59 l better inform interventions and assessment endeavors.

60 hod described here will greatly enable these endeavors.

61 ranks as one of the most successful of human endeavors.

62 ntial for students as they considered future endeavors.

63 r future deoxysugar biosynthetic engineering endeavors.

64 erials impacts success in tissue engineering endeavors.

65 ue, sulfone 34 should prove useful in future endeavors.

66 discuss how recent reports will guide future endeavors.

67 ncovalent and covalent hits emerge from such endeavors.

68 ll as to offer guidance for future synthetic endeavors.

69 This review gives an overview of such endeavors.

70 s is an important problem in many scientific endeavors.

71 in resource dependent and potentially risky endeavors.

72 substituted dendralenes in future synthetic endeavors.

73 ill undoubtedly assist future drug discovery endeavors.

74 How far has neuroscience progressed in this endeavor?

75 and African rather than just North American endeavor, (2) realism is better suited to social epidemi

76 To maintain scientific rigour in these endeavors, a comprehensive understanding of statistical

77 Even though this is a challenging endeavor and PPIs have long been regarded as "undruggabl

78 of the Prostate Strategic Urologic Research Endeavor and who were followed for an average of 2 y.

79 posed in the target article is a challenging endeavor and will require large-scale data sets with den

80 e discovery is a critical component of these endeavors and the use of nontraditional model organisms

81 ntegral part of the foundation of scientific endeavor, and methods and data sharing are complementary

82 Innovation is central to the scientific endeavor, and yet the current system of funding in the U

83 PATRIC's outreach activities, collaborative endeavors, and future research directions is provided.

84 ng discoveries that have resulted from these endeavors, and the future of this stimulating field.

85 r views on NDI chemistry for future research endeavors, and we outline what we believe are the key ob

86 Emerging scientific endeavors are creating big data repositories of data fro

87 Future endeavors are envisioned for the development of an array

88 These endeavors are important owing to a rising world populati

89 Although extensive research endeavors are pursued to target ideal molecular sieves a

90 These endeavors are, however, complicated by a lack of general

91 last few decades a surge in total synthesis endeavors around the world led to a remarkable collectio

92 We refer to this endeavor as "individualized health." The present article

93 lmology has benefited tremendously from this endeavor as well.

94 licability to other brain structure-function endeavors as well.

95 have proven unsuccessful to date, hampering endeavors at understanding molecular mechanisms of thera

96 Meta-analysis is essential to this endeavor because large sample sizes are required for det

97 spectrometry are appealing methods for this endeavor because, potentially, a large amount of informa

98 Here we initiate this endeavor by gathering R-fMRI data from 1,414 volunteers

99 Here, we contribute to this endeavor by reporting on the development of an (18)F-lab

100 hodologies shows promise for augmenting such endeavors by enhancing researchers' ability to detect mo

101 of the Prostate Strategic Urologic Research Endeavor (CaPSURE) registry and 19,265 men in the Japan

102 of the Prostate Strategic Urologic Research Endeavor (CaPSURE) registry.

103 of the Prostate Strategic Urologic Research Endeavor (CaPSURE), patients were compared by ethnicity,

104 of the Prostate Strategic Urologic Research Endeavor [CaPSURE]; enrolled 1995 through 2007) external

105 nt of nanochemistry, there exists a research endeavor centered around intermetallic nanocrystals, whi

106 Pioneering such endeavors could yield constructs that recapitulate disea

107 In such endeavors, DNA is the current building block of choice b

108 t because of the inherent difficulty of this endeavor due to the presence of the skull.

109 specificity in prokaryotes is a challenging endeavor due to the similar overall architecture of N-te

110 These endeavors establish a systematic paradigm by which to in

111 Several scientific endeavors examining the presence of CCSVI in MS are bein

112 reventative therapies are complex and costly endeavors focused on individuals likely to develop disea

113 enome editing into a practical and expedient endeavor for academic, industrial and clinical applicati

114 tion of cardiac imaging and model generation endeavors for mechanistic defibrillation analysis.

115 ey can be widely used to expedite scientific endeavors for the betterment of humankind.

116 nomy are the two most important green energy endeavors for the future.

117 o many of his other scientific and political endeavors, Franklin went on to experiment with oil, spre

118 One such endeavor, from our laboratories, focused on helix-formin

119 This endeavor has been hampered by the small number of specif

120 However, this endeavor has been hindered because of the lack of specif

121 A critical roadblock to this endeavor has been our inability to produce the prefusion

122 Crucial to this endeavor has been the development of an animal behaviora

123 n between basic science efforts and clinical endeavors has highlighted several additional functional

124 me therapies arising from tissue engineering endeavors have already entered the clinical setting succ

125 Although numerous research endeavors have been achieved in relation with the graphe

126 ions, significant interdisciplinary research endeavors have been focused on developing materials and

127 igating the environmental concerns, numerous endeavors have been made to seek green and sustainable e

128 Whereas previous endeavors have focused on the Campylobacter jejuni acety

129 These endeavors have led to the controlled synthesis of 25 nat

130 ss of decision-making in every area of human endeavor highlights the importance of understanding choi

131 This is an ambitious endeavor; however, the C4 pathway evolved from C3 on mul

132 , hyperarousal, and hypoarousal is a crucial endeavor in biological psychiatry.

133 nic and anthropogenic drivers is a difficult endeavor in such highly complex systems.

134 ical Atlantic Ocean on a transect of the R/V Endeavor in summer 2009 and analyzed for polycyclic arom

135 his perspective intends to cover my fruitful endeavor in the exploration of fluorine chemistry at the

136 a species adapts to its environment is a key endeavor in the study of evolution.

137 The discovery of odorant receptors led to endeavors in matching them with their cognate ligands.

138 beneficial role in tissue repair, and future endeavors in material design will potentially expand to

139 as emerged as one of the foremost scientific endeavors in recent years.

140 ampered by the narrow scope of many research endeavors in terms of both breadth of variables and comp

141 ational control will be important for future endeavors in the engineered biosynthesis of novel antica

142 pace is still far from saturated, and future endeavors in this direction will continue to be a valuab

143 when the enzyme was purified (a masochistic endeavor) in 1987, leading to the cloning of the Pemt cD

144 ve only been scarcely used in this important endeavor, in marked contrast to their prominent success

145 mple inputs is important for many scientific endeavors, including pharmaceutical, agrochemical, and m

146 stimation in group-averaged data and applied endeavors, including targeted neuromodulation.

147 Key to this endeavor is having sufficient resolution to determine th

148 ew is not meant to be exhaustive, as such an endeavor is impossible, but rather aims to balance bread

149 The overall goal of this endeavor is the integration of multifunctional complex o

150 A major current endeavor is to leverage this knowledge to develop new th

151 simple, and extensible neuron classification endeavor is unique in its detail, utility, and completen

152 One of the most challenging endeavors is synthesis of molecular nanocarbon.

153 tion of private and public funding for these endeavors is the best method of development.

154 l implementation, being a resource-consuming endeavor, is not exerted continuously or in simple tasks

155 The ENDEAVOR IV (Randomized Comparison of Zotarolimus-Elutin

156 (ENDEAVOR IV Clinical Trial; NCT00217269).

157 Insight from these endeavors led to critical modifications of our synthetic

158 ered to complement time-consuming and costly endeavors like the Cancer Genome Project.

159 The results from this endeavor not only led to improved metabolic stability, p

160 The endeavor of constructing natural products--the organic m

161 nvironmental consequences is critical in the endeavor of feeding the growing population sustainably a

162 In the endeavor of optimizing the sustainability of bioenergy p

163 combination, significantly complicating the endeavor of predicting the evolutionary dynamics of canc

164 iteria, which have impeded the long-standing endeavor of standardizing response assessment, are also

165 d as one of the milestones of the scientific endeavor of the 21(st) century.

166 urthermore be used as a model during current endeavors of applying definitions to other transcatheter

167 iology directly emanates from the pioneering endeavors of the five who wrote the seminal 1951/1952 ar

168 or nature of g-C3N4 has triggered tremendous endeavors on its structural manipulation for enhanced ph

169 Difficulties were encountered in this endeavor, owing to MUC1-imposed steric hindrance and ant

170 coherent analysis pipeline is not a trivial endeavor, particularly for microbiologists with limited

171 The primary endpoint of ENDEAVOR, progression-free survival, has been previously

172 Successful analytical endeavors require collaboration between clinicians, micr

173 tion in octogenarians, but the supplementary endeavor required to perform functional complete revascu

174 Success in this endeavor requires a full understanding of the mechanisms

175 This endeavor requires the conversion of cellulosic biomass i

176 We highlight areas of societal endeavor requiring additional efforts to achieve the Aic

177 The randomized TWENTE (The Real-World Endeavor Resolute Versus Xience V Drug-Eluting Stent Stu

178 The TWENTE (Real-World Endeavor Resolute vs Xience V Drug-Eluting Stent Study i

179 e near future, the ultimate success of these endeavors rests on our ability to translate what is lear

180 This endeavor resulted in the identification of several small

181 In contrast to many other human endeavors, science pays little attention to its history.

182 Valve surgery quality improvement endeavors should focus on a more comprehensive assessmen

183 nish lapses that inevitably occur in complex endeavors such as scientific research.

184 essential for immediate large-scale genomic endeavors such as the 1000 Genomes Project, and is cruci

185 At the forefront of new synthetic endeavors, such as drug discovery or natural product syn

186 discuss experimental design issues for such endeavors, such as how many crosses are required and whi

187 Results from this endeavor suggest that 1,2-cis arabinofuranosides can be

188 Introducing a new vaccine is a large-scale endeavor that can face many challenges, resulting in int

189 restrict androgen synthesis selectively, an endeavor that could benefit from the enhanced understand

190 rofabricated platform, is an active research endeavor that evolved out of the larger field of microfl

191 al portions of the delta is now underway, an endeavor that is expected to cost $50-100B over the next

192 ltiple individual human genomes is a complex endeavor that is rapidly gaining importance with the inc

193 chinson-Gilford progeria syndrome (HGPS), an endeavor that many view as a "poster child" for how basi

194 pment of lesions observable on MRI scans, an endeavor that may be facilitated by newborn screening fo

195 ction substrate scope is often a qualitative endeavor that provides general indications of substrate

196 elivery of burn care is a resource-intensive endeavor that requires specialized personnel and equipme

197 nd-point of an extensive medicinal chemistry endeavor that spans almost three decades.

198 genetic causes within the core eudicots--an endeavor that will have broader implications for the int

199 Shape may be so important in some of these endeavors that an organism may change its morphology to

200 r offers a critical review of major research endeavors that inform our knowledge of risk to communiti

201 equencing and discuss some of the scientific endeavors that it has enabled.

202 the cause of this mismatch could be a worthy endeavor, the discrepancy does not appear to question th

203 In this endeavor, the most exploited ligand has been a structura

204 To aid in this endeavor, the present article describes a Model for Unde

205 Like all predictive endeavors, the imaging of such "potential" is a daunting

206 can be applied to any biological engineering endeavor, this article will focus on providing a brief o

207 on to stand aside and abstain from the joint endeavor, this paves the way for the emergence and estab

208 We endeavor throughout to suggest mechanisms and implicatio

209 ated great potential and success toward this endeavor; thus, in this work, we present a comprehensive

210 to measles control efforts in countries that endeavor to achieve higher levels of population immunity

211 The ICHOM will endeavor to achieve wide buy-in of this set and facilita

212 In the endeavor to associate genetic variation with complex tra

213 Providers using current guidelines should endeavor to collect practice-based evidence to validate

214 In this framework, we endeavor to correlate state-of-the-art chemical design,

215 Herein, we endeavor to define the essential aspects of quaterpyridi

216 A longstanding endeavor to define the genetic lesions that drive myeloi

217 age-specific models remain useful, we should endeavor to develop a universal model of reading acquisi

218 conversion and molecular nanosciences and we endeavor to discuss the impact of the covalent approach

219 s to influence practice recommendations, and endeavor to elicit and respect family preferences in col

220 This article describes our endeavor to elucidate the chemical mechanism and charact

221 le obstacle for bacteria to overcome if they endeavor to endure this endozoonotic cycle.

222 ion type over another, future studies should endeavor to evaluate the relationship between preoperati

223 Within each section we will endeavor to highlight critical design elements and how t

224 In an endeavor to identify novel vaccine targets, we tested pr

225 Throughout the review, we endeavor to identify the specific HDAC targeted by HDACi

226 dly benefit patients and clinicians in their endeavor to improve management and outcome.

227 Permitting qualified researchers to endeavor to independently reproduce the analyses used in

228 the challenges encountered by scientists who endeavor to map these whole-body connectomes in large an

229 In a collaborative endeavor to minimize maintenance immunosuppression in pe

230 In this study, we endeavor to obtain a global understanding of cell lineag

231 Public health initiatives endeavor to raise public awareness about acute stroke to

232 We endeavor to review important new advances in acute pancr

233 Here, we endeavor to summarize the existing data on the genetic a

234 nsitive multimodal imaging techniques should endeavor to transform these group-based findings to indi

235 In the endeavor to understand how our brains enable our multifa

236 one's experiences or explanatory model; (2) Endeavor to understand the individual patient before you

237 Here we endeavor to understand the neural underpinnings of comor

238 However, most surrogates endeavored to balance their own knowledge of the patient

239 When mistrust was an issue, physicians endeavored to build a more trusting relationship with th

240 re commonly observed background findings and endeavored to characterize the incidence of spontaneous

241 We have also endeavored to define the interface that governs the asse

242 We have presently endeavored to determine if K-ras mutations, present in a

243 Therefore, we endeavored to determine the association between the risk

244 We endeavored to determine under what conditions a strategy

245 native in renal transplantation, and we have endeavored to develop a clinically translatable, belatac

246 Here, we endeavored to develop a DNA four-way junction based elec

247 role in the innate and adaptive immunity, we endeavored to develop a strategy to improve the efficacy

248 es in one of our drug discovery programs and endeavored to devise an asymmetric hydrogenation strateg

249 In this work, we endeavored to dissect, using genetic and biochemical app

250 Next, we endeavored to establish a cellular system for testing th

251 Although we have endeavored to follow best practices, there is little pub

252 We have endeavored to gain insight into the 3D architecture of t

253 We endeavored to identify a stereotypic, dominant, mature v

254 Therefore, we have endeavored to identify new compounds that can specifical

255 We have endeavored to identify, abstract, and present all availa

256 Several research groups have endeavored to produce strongly basic zeolites by treatin

257 America Clinical Affairs Committee has long endeavored to quantify the value of ID physicians to the

258 Studies have endeavored to reconcile whether dysfunction of neutrophi

259 For decades, protein engineers have endeavored to reengineer existing proteins for novel app

260 In this study, we endeavored to reveal detailed structure-activity relatio

261 We endeavored to test these possibilities, focusing on the

262 scovered in viral systems, the current study endeavored to: (i) identify -1 PRF signals in genomic da

263 In contrast, the NCI is endeavoring to estimate the increased lung cancer risk f

264 on herding behavior arises among individuals endeavoring to satisfy both nutritional and safety deman

265 d interests of researchers, whether they are endeavoring to understand the basis of development and d

266 ents were offered as well as future research endeavors to accommodate anticipated environmental chang

267 iative at the Union of Concerned Scientists, endeavors to change this dynamic to strengthen the role

268 for the design of such a controller, that it endeavors to control the natural dynamics of the limb, t

269 Synthetic endeavors to create non-natural bioactive small molecule

270 Endeavors to develop highly sensitive, fast, stable and

271 uorogenic substrate can be applied in future endeavors to develop substrates for detecting real-time

272 entral role these alignments now play in our endeavors to establish the tree of life and to identify

273 propose a simple centromere size model that endeavors to explain both observations.

274 Resequencing endeavors to find low-frequency variants implicated in c

275 porting and prioritizing meaningful research endeavors to further evaluate these models.

276 is a distinct subspecialty of radiology that endeavors to improve the efficiency, accuracy, and relia

277 issection strategy should greatly facilitate endeavors to link molecular variation with phenotypic va

278 This work sets the foundation for future endeavors to resolve key questions in microbial ecology

279 ing research in deceased donors, this report endeavors to stimulate the creation of a multi-disciplin

280 This review endeavors to summarize the recent advances in our unders

281 in vitro antiplasmodial activity sparked new endeavors to synthesize members of this family of second

282 We suggest the authors' endeavor toward a science of intentional change may bene

283 In this review, we describe the main endeavors toward development of treatments that will enh

284 The phase 3 ENDEAVOR trial was a head-to-head comparison of two prot

285 We were successful in this endeavor, using a comprehensive stepwise approach, leadi

286 c instability against dissociation make this endeavor very challenging.

287 ENDEAVOR was a phase 3, open-label, randomised controlle

288 The central challenge in this synthesis endeavor was uniting the hexahydro-2H-pyrazinopyrrolo[2,

289 Critical to these endeavors was a marked improvement in our previously rep

290 As a new step in this endeavor, we asked how plant species richness relates to

291 In this endeavor, we examined both between and within-subject co

292 To assist this endeavor, we have used an inducible switchgrass cell sus

293 To assist in this endeavor, we investigated motor fiber organization in th

294 the few reported mechanistic studies on this endeavor were conducted in anesthetized rats.

295 This endeavor will benefit from technical advances in simulta

296 This large-scale endeavor will facilitate the consistent management of fa

297 ive and engaging visualizations and artistic endeavors will have growing implications on education, c

298 ith existing detection platforms has been an endeavor with few opportunities until now.

299 Network science is an interdisciplinary endeavor, with methods and applications drawn from acros

300 scularization (TLR), compared with data from Endeavor zotarolimus-eluting stent (E-ZES) trials, adjus