ライフサイエンスコーパス: endo

1 dolin-1-one (E-5-exo), and isoquinolinone (6-endo).

2 Xyl2 contained a protein with similarity to endo-1,4-beta-xylanase.

3 We identified the central role of the endo-1,6-beta-glucanase in 1,6-beta-glucan depolymerizat

4 ta-glucan and encodes two enzymes, a surface endo-1,6-beta-glucanase, BT3312, and a periplasmic beta-

5 or either a 2'-endo, 3'-exo (South), or a 3'-endo,2'-exo (North) conformation.

6 rbornenes with "opposite" chiralities of the endo-2-substituted-5,6-norbornene skeleton, can be prepa

7 propagating species and the chirality of the endo-2-substituted-5,6-norbornene skeleton.

8 where A and B are two enantiomerically pure endo-2-substituted-5,6-norbornenes with "opposite" chira

9 e of fluorinated sugar rings for either a 2'-endo, 3'-exo (South), or a 3'-endo,2'-exo (North) confor

10 referentially polymerized l-lactide, whereas endo-6 preferred d-lactide as the substrate.

11 o-3,5-diphenylpyrrolidine-2-carboxylic acid (endo-6) and (2S,3S,4R,5S)-1-methyl-4-nitro-3,5-diphenylp

12 ses derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could not recognize triantennary N-g

13 galactosyl substitution and was shown to be endo-acting generating a more diverse mixture of oligosa

14 iveness of this array for detecting exo- and endo-acting glycoside hydrolase activity using commercia

15 hat the bacterium expressed a single-surface endo-acting lyase that cleaved HS, reflecting its higher

16 idone products derived from both 5-exo and 6-endo addition of the nitrogen to the pendent alkyne.

17 ne stereoisomer in agreement with the known "endo-alkyl rule".

18 med by a stereoselectivity controlled by the endo-alkyl rule.

19 ix[2]pseudorotaxane, namely, endo-benzyl and endo-alkyl, are formed by a stereoselectivity controlled

20 saccharide inhibitors, their binding to GH99 endo-alpha-1,2-mannanases, and their structural analysis

21 Endo-alpha-1,2-mannosidases and endo-alpha-1,2-mannanases, members of glycoside hydrolas

22 Endo-alpha-1,2-mannosidases and endo-alpha-1,2-mannanase

23 -alphaS (NTAc-alphaS) and endogenous alphaS (Endo-alphaS) from human erythrocytes, we show that N-ter

24 The long-term outcome after ENDO and adjuvant EPI substrate ablation of VT in arrhyt

25 nces occurred in 16 and in 3 patients in the Endo and Epi-Group, respectively (Grey-test, P=0.2).

26 xyproline, the Xaa proline adopts a range of endo and exo conformations.

27 combination of IdeS and the endoglycosidases EndoS and EndoS2 to comprehensively map the glycan conte

28 tiarrhythmic drug therapy after endocardial (ENDO) and adjuvant epicardial (EPI) substrate modificati

29 ned by asynchronous activation of the atrial endo- and epicardial layer and transmurally propagating

30 Intraoperative mapping of the endo- and epicardial right atrial wall was performed dur

31 high-resolution mapping of the right atrial endo- and epicardial wall during AF in humans.

32 W indicate that muscular connections between endo- and epicardium underlie EBW and that a slight degr

33 y using micrococcal nuclease, which has both endo- and exo-nuclease activity, to fragment the chromat

34 king along microtubules and through the cell endo- and exocytic pathways can be next visualized via l

35 ave been developed to study the formation of endo- and exogenous DNA adducts.

36 These displayed endo- and exoglucanase activity on the beta-1,3-1,6-gluc

37 Artemis is a vertebrate nuclease with both endo- and exonuclease activities that acts on a wide ran

38 te source, a phenotype dependent on secreted endo- and exonucleases.

39 conjugation of reduced glutathione (GSH) to endo- and xenobiotics.

40 the replacement by RRP1 is coupled with the endo- and/or exo-ribonucleolytic cleavage of pre-rRNA re

41 ancy under natural conditions, namely para-, endo-, and ecodormancy in summer, fall, and winter, resp

42 xo-mode of cyclization rather than the usual endo-attack employed in the few radical syntheses of cyc

43 entations of calix[2]pseudorotaxane, namely, endo-benzyl and endo-alkyl, are formed by a stereoselect

44 GH5_26 contains members that display either endo-beta(1,4)-glucanase or beta(1,3;1,4)-glucanase acti

45 the -3 subsite and turns the enzyme into an endo-beta(1,4)-glucanase.

46 We have characterized endo-beta-1,3-glucanase (Eng) from 3 species of Pneumocy

47 u-176, a conserved catalytic residue in GH16 endo-beta-1,3-glucanases, as essential for Rv0315 to ind

48 and human NK cells express low levels of the endo-beta-D-glucuronidase heparanase that increase upon

49 The delivery of heparanase, the endo-beta-D-glucuronidase that degrades HS, accelerated

50 Importantly, endo-beta-galactosidase coupled with MALDI-MS allowed th

51 e conformer adopts a nearly synperiplanar Pd/endo-beta-H arrangement, whereas for the analogous Pd si

52 of the five-membered lactone the smallest Pd/endo-beta-H dihedral angle is observed for a conformer w

53 ated with the dihedral angles between Pd and endo-beta-H.

54 An enzymatic fingerprinting method using endo-beta-mannanase, in addition to being used to differ

55 Chemical synthesis was combined with endo-beta-N-acetylglucosaminidase (ENGase) catalysis to

56 The endo-beta-N-acetylglucosaminidases (ENGases) are an enzy

57 8 is an exo-beta1,3-glucanase and Eng1 is an endo-beta1,3-glucanase.

58 c dienophiles furnished functionalized ortho-endo bicyclo[2.2.2]octenone derivatives with high regio-

59 In the fetal nervous system, (endo)cannabinoid-sensing receptors and the enzymatic mac

60 tereo- and regioselectivity, the 7-exo and 8-endo carbocyclization modes by attack of the indole grou

61 tein (LDL) from UNx rats with normal EPI and ENDO cardiomyocytes recapitulated the electrophysiologic

62 current (Ito) in EPI but not in endocardial (ENDO) cardiomyocytes of UNx rats led to a decreased tran

63 roliferation and -migration observed in LKB1(endo-/-) cells.

64 Endo-cervical adenocarcinoma accounts for about 10-30% o

65 midal species (Pb(II)S3 and As(III)S3) in an endo conformation oriented toward the 3SCC C-termini, wh

66 led a strong conformational bias for the C3'-endo conformation to maintain potent biochemical and who

67 etic properties were associated with the C2'-endo conformation.

68 between non-helical (C2-endo) to helical (C3-endo) conformations during formation of two distinct exc

69 5'-deoxyadenosyl group from C2'-endo to C3'-endo could contribute to initiation of catalysis.

70 flow, and less tissue hypoxia than TbetaRII(endo+/+) counterparts.

71 l conduction on myocardial activation during ENDO-CRT and EPI-CRT.

72 ia left ventricular (LV) endocardial pacing (ENDO-CRT) is associated with improved acute hemodynamic

73 logical explanation for improved response to ENDO-CRT.

74 ycling vesicle pool (also referred to as exo-endo cycling pool) at the expense of reserve pool vesicl

75 amino-beta-hydroxyallenes was effective as 5-endo cyclization by addition of amino functionality to t

76 The success of the kinetically disfavored 5-endo cyclization was attributed to the formation of capt

77 atalyzed radical cyclization, and a double 6-endo cyclization with catalyst loadings as low as 0.01 m

78 a d-xylofuranose precursor, [I(+)]-induced 6-endo cyclization, and 1,2-trans stereoselective glycosyl

79 eads almost exclusively to the corresponding endo cycloadduct, which is in good agreement with previo

80 pyrans through a chemo- and regioselective 6-endo cycloetherification.

81 ndoglycosidases derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could not recognize tria

82 highly functionalized cyclohexenes with high endo diastereoselectivity.

83 erein we report studies exploring the use of endo-dicyclopentadiene (DCPD), a common ROMP monomer, to

84 However, exclusive formation of 7-endo-dig cyclization products was observed with internal

85 eting reaction mechanisms-a 5-exo-dig or a 6-endo-dig cyclization-leading to two regioisomeric interm

86 more electrophilic alkynyl carbon through 6-endo-dig cyclization.

87 g alpha-amino ynone generation followed by 6-endo-dig cyclization.

88 menes using an Overman rearrangement and a 6-endo-dig hydroarylation.

89 ntramolecular 5-exo-dig mode followed by a 7-endo-dig mode to give the benzofuroazepines via formatio

90 g step of the interrupted cascade from the 6-endo-dig nucleophilic attack to the fragmentation of the

91 ple bond, and cyclization via an exclusive 6-endo-dig process.

92 was dependent on both the ring size and exo/endo disposition.

93 x in which two substrates bind in an unusual endo-endo fashion because of interligand H-bonding withi

94 ) patients, including 13 who crossed over to ENDO-EPI after VT recurrence during follow-up, after END

95 y 2013, we started to systematically perform endo-epicardial access (Epi-Group) as first-line approac

96 Asynchronous endo-epicardial activation ranged between 0.9 and 55.9%

97 d to determine the incidence of asynchronous endo-epicardial activation times (>/=15 ms) of opposite

98 Endo-epicardial asynchrony may play a major role in the

99 ium underlie EBW and that a slight degree of endo-epicardial asynchrony required for EBW to occur is

100 To provide direct proof of endo-epicardial asynchrony, we performed simultaneous hi

101 the arrhythmogenic substrate and result from endo-epicardial asynchrony, which also occurs to some de

102 We analyzed the endo-epicardial electroanatomical mapping (EAM) voltage

103 al fibrillation waves could be attributed to endo-epicardial excitation.

104 Endo-epicardial LPs were recorded in 2/3 patients, more

105 n and density predict scar transmurality and endo-epicardial presence of LPs, although DS is not alwa

106 ctroanatomical mapping-based VT ablation (26 endo-epicardial procedures) from 2010-2012.

107 evidence for asynchronous activation of the endo-epicardial wall during AF in humans.

108 Failure of endo/epicardial ablation attempts was because of VT of i

109 For cyclopentadiene, the endo-ester adducts were favored regardless of steric per

110 Discrete endo,exo-norbornenyl dialkylesters (dimethyl DME, diethy

111 In the absence of copper, endo-exo selectivity is predicted to arise from substitu

112 The factors controlling the reactivity and endo/exo selectivity of the Diels-Alder reactions involv

113 The endo/exo selectivity of this reaction can be controlled

114 d to investigate the factors influencing the endo/exo selectivity.

115 r these cycloaddition reactions, the product endo:exo ratios, when compared to those in organic solve

116 ace adhesion receptors that are modulated by endo-exocytic trafficking, but existing tools to study t

117 ntegrin function is dynamically modulated by endo-exocytic trafficking, however, major mysteries rema

118 Alterations of endo/exocytic proteins have long been associated with ma

119 g on the mechanisms underlying the impact of endo/exocytic proteins in cancer, a scenario emerges in

120 istribution of integrins through a regulated endo-exocytosis cycle, but the complex molecular mechani

121 at the leading edge during cell motility and endo/exocytosis, whereas the WASH complex is involved in

122 ity, cellulose-binding domain targeting, and endo/exoglucanase synergy.

123 Notably, the Endo-F3 D165A and D165Q mutants demonstrated high accept

124 ystem, we have further demonstrated that the Endo-F3 mutants are highly efficient for glycosylation r

125 The Endo-F3 mutants represent the first endoglycosidase-base

126 The Endo-F3 mutants were able to use both bi- and triantenna

127 ethkingia meningoseptica endoglycosidase F3 (Endo-F3) of the GH18 family, which are devoid of the inh

128 e other systems displaying different exo and endo functionalities within the cage assembly were gener

129 oordinate C atom bends 31 degrees toward the endo-fused cyclopropane bond, elongating it to r = 1.69

130 g of the degradation mechanism by endogenous endo-galactanase and/or exogenous microbial enzymes migh

131 hen compared to batch production with a pure endo-galacturonase enzyme, demonstrating its feasibility

132 tifs that engender predominant mixed-linkage endo-glucanase activity vis a vis predominant endo-xylog

133 ing (carboxymethyl)cellulases, mixed-linkage endo-glucanases, and endo-xyloglucanases.

134 r reablation) occurred in 14 patients of the Endo-group and in one patient in the Epi-group (event-fr

135 Endo H was used to collapse high mannose oligosaccharide

136 cosidase F (PNGase F) and endoglycosidase H (Endo H).

137 individual monomer units, and PhoD catalyzes endo-hydrolysis at nonspecific sites throughout the poly

138 Net deposition was shown for ENDO-I on all expeditions, while the net exchange direct

139 surface water, whereas some CUPs increased (ENDO-I, CHT, and TFN) or showed no significant change (C

140 dosulfans and metabolite endosulfan sulfate (ENDO-I, ENDO-II, and ENDO SUL), chlorothalonil (CHT), ch

141 s and metabolite endosulfan sulfate (ENDO-I, ENDO-II, and ENDO SUL), chlorothalonil (CHT), chlorpyrif

142 The results suggest that Endo III induces several fast sequential conformational

143 Escherichia coli endonuclease III (Endo III or Nth) is a DNA glycosylase with a broad subst

144 Endo III possesses two types of activities: N-glycosylas

145 ng our data with the available structures of Endo III, we conclude that this glycosylase uses a multi

146 the critical combination of factors C4-(exo/endo), intraresidue H-bonding, stereoelectronic (R/S) an

147 This protocol, based on the 5-endo iodocyclization reaction of o-(alkynyl)styrenes, re

148 ed Ni(0) isomers to the catalytically active endo-isomers, but decreases the rate of protonation of N

149 of the methyl ketone in this structure to an endo isopropenyl group.

150 New endo-leaks were associated with increased aneurysm size

151 + ATPase (V-ATPase), the key proton pump for endo-lysosomal acidification, and two previously unchara

152 ECs internalized myelin, which was routed to endo-lysosomal compartment for processing in a time-depe

153 at once cleaved, the drug escapes the acidic endo-lysosomal compartment into the cytosol and traffics

154 ization of the NDP receptor complex into the endo-lysosomal compartment.

155 e is the most prevalent nuclease activity in endo-lysosomal compartments and that additional stabiliz

156 e majority of dendrimers are directed to the endo-lysosomal compartments in both cell types.

157 holesterol efflux from cellular membrane and endo-lysosomal compartments, reduces lysosomal lipid acc

158 utics depend on endocytosis and release from endo-lysosomal compartments.

159 zyme YOD1, which we term ELDR components for Endo-Lysosomal Damage Response.

160 This study suggests that endo-lysosomal impairment in neurons might play an impor

161 Interestingly, cells with endo-lysosomal membrane permeabilization (LMP) are more

162 lphaS pathology with galectin-3 (a marker of endo-lysosomal membrane rupture) in the basal forebrain

163 stablish a role for Parkin in regulating the endo-lysosomal pathway and retromer function and raise t

164 egradation of the EGF receptor (EGFR) by the endo-lysosomal pathway.

165 r sorting and degradation pathways involving endo-lysosomal vesicles, the ubiquitin-proteasome system

166 that PorB increases the level of OVA in the endo-/lysosomal cellular compartment of BMDCs, increases

167 nd in vivo administration of chloroquine, an endo/lysosomal inhibitor, mimicked Pepstatin A effect on

168 Caveolin-1 associates with the endo/lysosomal machinery of cells in culture, suggesting

169 mammalian TPC channels have been shown to be endo/lysosomal Na(+)-selective or Ca(2+)-release channel

170 late endosomes to time fusion events in the endo/lysosomal pathway.

171 r vesicular trafficking, immune response and endo/lysosomal processes.

172 The endo/lysosomal trafficking system may coordinate insulin

173 man cells, we visualized alphaS aggregation, endo-lysosome distribution, and endo-lysosome rupture in

174 endocytosis-mediated seeding associated with endo-lysosome rupture and have significantly reduced see

175 aggregation, endo-lysosome distribution, and endo-lysosome rupture in real-time.

176 D, but not in age-matched controls, suggests endo-lysosome rupture is involved in the formation of al

177 plasma membrane or via endocytosis-mediated endo-lysosome rupture, leading to formation of endo-lyso

178 eading to formation of endo-lysosome-free or endo-lysosome-associated alphaS aggregates, respectively

179 do-lysosome rupture, leading to formation of endo-lysosome-free or endo-lysosome-associated alphaS ag

180 digested phagocytic material inside enlarged endo-lysosomes and as a result, hemotin mutants have red

181 messenger NAADP triggers Ca(2+) release from endo-lysosomes.

182 eus after acid-triggered drug release in the endo-lysosomes.

183 conjugate enables cholesterol clearance from endo/lysosomes of Npc1 mutant (Npc1(-/-)) cells.

184 rom abnormal cholesterol accumulation in the endo/lysosomes.

185 onal homologue of the recently reported MltG endo-lytic transglycosylase of Escherichia coli.

186 ported endoglycosidases derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could not recogn

187 dosperm-specific maternally expressed genes (endo-MEGs) were associated with maternally preferred H3K

188 Around the transcription start sites of endo-MEGs, DNA methylation and H3K4me3 specifically mark

189 same allele-specific epigenetic features as endo-MEGs, indicating similar mechanisms for the regulat

190 y, pos-1 mutants exhibit striking defects in endo-mesoderm development but have wild-type distributio

191 ether, achieve precise spatial expression of endo-mesoderm fates in C. elegans embryos.

192 distributions of SKN-1, a key determinant of endo-mesoderm fates.

193 uction of protected 2,3-dideoxy-2-fluoro-2,3-endo-methylene-pentofuranoses from d-glyceraldehyde and

194 d 2,3-dideoxy-2-fluoro-3-C-hydroxymethyl-2,3-endo-methylene-pentofuranoses from d-isoascorbic acid, v

195 angiogenic potential compared with TbetaRII(endo+/+) mice under basal conditions.

196 or unilateral ureteral obstruction, TbetaRII(endo+/-) mice exhibited less tubulointerstitial fibrosis

197 ozygous TGF-beta receptor knockout (TbetaRII(endo+/-)) mice to explore whether curtailed TGF-beta sig

198 Tumors implanted in LKB1(endo-/-) mice but not macrophage-specific LKB1-knockout

199 thelial cells but not in macrophages in LKB1(endo-/-) mice.

200 ndothelial cell-specific LKB1-knockout (LKB1(endo-/-)) mice by crossbreeding vascular endothelial-cad

201 Consistently, LKB1(endo-/-) mouse tissues including the lung, skin, kidney

202 r vascularization and suggest that targeting Endo-MT may offer selective and efficient strategies for

203 axis that controls VE-cadherin degradation, Endo-MT, and vascular abnormality.

204 known as endothelial mesenchymal transition [Endo-MT]), which is characterized by EC expression of fi

205 after VT recurrence during follow-up, after ENDO-only ablation.

206 ecurrent VT or persistent inducibility after ENDO-only ablation.

207 Four adducts, presenting an endo or exo configuration and proximal or distal geometr

208 oselectivity to be modulated to favor either endo- or exo-ester adducts.

209 Covalent binding of endo- or exogenous chemicals to DNA results in the forma

210 stion that UGT8 is involved in metabolism of endo- or xenobiotics.

211 o overcome the inherent preference for the 6-endo pathway and provide the highest combination of 5-ex

212 +) led to the toposelective formation of the endo-pentylpseudorotaxane stereoisomer in agreement with

213 We find residual carboxy- and endo-peptidase gamma-secretase activities, similar to th

214 endo-peptidases act first followed by the successive act

215 osed by a homogalacturonan unit linked to an endo-PG resistant unit.

216 and shared intermediate pathophenotypes, or endo(pheno)types.

217 concentration, including those in the sarco(endo)plasmic reticulum [S(E)R], are primarily coordinate

218 We also observed that sarco(endo)plasmic reticulum ATPase (SERCA) expression was ele

219 sarcolipin (SLN), an uncoupler of the sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA) pump, could

220 (PLN) is an effective inhibitor of the sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA).

221 The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) and phospho

222 caused by both inactivation of AKT and sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA)2a signallin

223 aximal turnover rate than the purified sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1a).

224 iac myocytes through regulation of the sarco(endo)plasmic reticulum Ca(2+)-ATPase 2A (SERCA2A) Ca(2+)

225 l ankyrin 1 (sAnk1) interacts with the sarco(endo)plasmic reticulum Ca(2+)-ATPase in skeletal muscle

226 SERCA1, the sarco(endo)plasmic reticulum Ca(2+)-ATPase of skeletal muscle,

227 ns from strawberry fruits were digested with endo-polygalacturonase M2 from Aspergillus aculeatus and

228 occur regioselectively and exhibit a notable endo preference, thus resulting in the controlled format

229 n-water reactions but enhanced the rates and endo products for in-water reactions.

230 r allowed to proceed further to the formal 6-endo products via homoallylic ring expansion.

231 llylic ring expansion to yield the formal "6-endo" products with aromatization via stereoelectronical

232 Our previous study has shown that endo-Protoporphyrin IX based SDT (ALA-SDT) could induce

233 A C4-endo pucker at X-site and C4-exo pucker at Y-site have b

234 preclinical evidence for a role of FOXA1 in Endo-R breast cancer as well as evidence for its clinica

235 OXA1 and ER transcriptional reprogramming in Endo-R cells.

236 A1 is gene-amplified and/or overexpressed in Endo-R derivatives of several breast cancer cell line mo

237 , yet its aberration in endocrine-resistant (Endo-R) breast cancer is unknown.

238 cing the three stereocenters with a high exo endo ratio (10:1) and excellent enantioselectivity (>98%

239 proline has a strong propensity to adopt an endo ring conformation, whilst when Yaa is hydroxyprolin

240 activation was dependent on both kinase and endo-RNase activities of Ire1p.

241 based on the activity of an uncharacterized endo-RNase that cleaves the viral RNA substrate at a deg

242 se from this model and our in vivo data that endo S phase-coupled destruction of Dap reduces the thre

243 d to be much more active in general than the Endo-S mutants for transglycosylation.

244 In contrast to the previously reported Endo-S mutants that are limited to action on complex typ

245 At the onset of endocycle S (endo-S) phase, H1 is heavily and specifically loaded int

246 ously reported endoglycosidases derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could no

247 The usefulness of these Endo-S2 glycosynthase mutants was exemplified by an effi

248 In addition, the Endo-S2 glycosynthase mutants were found to be much more

249 ted to action on complex type N-glycans, the Endo-S2 glycosynthases described here, including D184M a

250 from Streptococcus pyogenes of serotype M49 (Endo-S2) and the evaluation of the resulting mutants for

251 f stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum (ER/SR) Ca(2+) sensor, is un

252 re calcium (Ca(2+) ) release channels on the endo/sarcoplasmic reticulum (ER/SR).

253 f stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum Ca(2+) sensor.

254 The sequences feature highly endo-selective [2 + 2]-photocycloaddition reactions foll

255 [Rh(CO)2Cl]2 is as an effective catalyst for endo-selective cyclizations and cascades of epoxy-(E)-en

256 The reaction is endo-selective in the presence of Lewis acid catalyst.

257 haped transition state dictate the exclusive endo selectivity and enabled the development of a highly

258 tative understanding into the origins of the endo selectivity of the process as well as the influence

259 nding highly substituted pyrrolizidines with endo selectivity.

260 The exo- or endo-selectivity of bicyclic scaffolds depends on the se

261 hila functional specialization of the miRNA, endo-siRNA and exo-siRNA pathway is aided by the dsRBPs

262 , Loqs-PA participates in both the miRNA and endo-siRNA based pathways.

263 Drosophila hairpin RNAs (hpRNAs) generate an endo-siRNA class with predominant expression in testes.

264 rm (paternal) or oocyte (maternal) miRNA and endo-siRNA contents are required for fertilization and p

265 , we found that sperm with altered miRNA and endo-siRNA profiles could fertilize wild-type (WT) eggs,

266 A core component of P granules, the endo-siRNA-binding Argonaute protein CSR-1, has recently

267 , nuclear RNAi ensures robust inheritance of endo-siRNAs and deposition of repressive H3K9me3 marks a

268 a crucial function of paternal miRNAs and/or endo-siRNAs in the control of the transcriptomic homeost

269 icroRNAs, endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), have be

270 expressed endogenous small interfering RNAs (endo-siRNAs) transmit multigenerational epigenetic infor

271 RNAs) and endogenous small-interfering RNAs (endo-siRNAs), are key gene regulators in eukaryotes, pla

272 ocytes) partially deficient in miRNAs and/or endo-siRNAs, thus providing a unique opportunity for tes

273 ational fertility and acts as an effector of endo-siRNAs.

274 Duplex RNA segments have A-form C3' endo sugar puckers but widened major groove widths, givi

275 ite endosulfan sulfate (ENDO-I, ENDO-II, and ENDO SUL), chlorothalonil (CHT), chlorpyrifos (CPF), and

276 a paradox in the functioning of prokaryotic (endo)symbionts.

277 hange of the 5'-deoxyadenosyl group from C2'-endo to C3'-endo could contribute to initiation of catal

278 mpanying transitions between non-helical (C2-endo) to helical (C3-endo) conformations during formatio

279 these stress-associated signals induced the endo- to ecodormancy transition and growth competence.

280 When crown buds transitioned from endo- to ecodormancy, the ABA metabolites PA and DPA dec

281 ene with the divinyl ketone pi system in the endo transition state and a steric effect override the i

282 eoselectivity by selectively stabilizing the endo transition state.

283 echanism via the energetically favorable syn/endo-transition states.

284 endo-Tricyclo[3.2.1.0(2,4)]oct-8-ylidene is a foiled car

285 retro-3-exo path is faster than the direct 6-endo-trig closure, revealing the general exo-preference

286 This enables the usually unfavorable 5-endo-trig cyclization and merges it with 5-exo-dig closu

287 lkylpiperidines has been developed using a 6-endo-trig cyclization of (E)-enones.

288 The combination of formal 6-endo-trig cyclization with stereoelectronically optimize

289 (2H)-ones in excellent yields via a formal 5-endo-trig cyclization.

290 e absence of any reagent in a cascade SN2'-6-endo-trig fashion and is completely regioselective and h

291 anism, or through a kinetically controlled 5-endo-trig Mannich process.

292 on of benzothiazole-2-carboxylates via the 5-endo-trig process contrary to Baldwin's rule.

293 ceeds via a Cu(I)-catalyzed regioselective 5-endo-trig radical cyclization of 2,2,2-trichloroethyl vi

294 highly functionalized gamma-lactams via a 5-endo-trig radical-polar crossover process that was termi

295 to 95 %) and regioselectivities (5-exo vs. 6-endo) were achieved through catalyst control and sequent

296 within plant microbiomes, i.e., endophytes ("endo" = within, "phyte" = plant), can significantly modi

297 Endo-xylanase action on pretreated wheat chaff released

298 corated and that are recalcitrant to classic endo-xylanase attack.

299 ndo-glucanase activity vis a vis predominant endo-xyloglucanases in GH5_4.

300 llulases, mixed-linkage endo-glucanases, and endo-xyloglucanases.