ライフサイエンスコーパス: endo

1 Xyl2 contained a protein with similarity to endo-1,4-beta-xylanase.

2 We identified the central role of the endo-1,6-beta-glucanase in 1,6-beta-glucan depolymerizat

3 ta-glucan and encodes two enzymes, a surface endo-1,6-beta-glucanase, BT3312, and a periplasmic beta-

4 590+/-140 ms) and nonsustained focal waves (Endo: 1.2% versus Epi: 1.6%, P=0.669) were also observed

5 rbornenes with "opposite" chiralities of the endo-2-substituted-5,6-norbornene skeleton, can be prepa

6 propagating species and the chirality of the endo-2-substituted-5,6-norbornene skeleton.

7 where A and B are two enantiomerically pure endo-2-substituted-5,6-norbornenes with "opposite" chira

8 Transient rotations (Endo: 22% versus Epi: 19.2%, P=0.169; mean duration: 590

9 Epi: 46.8%, P=0.0194) and single wavefronts (Endo: 31.3% versus Epi: 28.1%, P=0.129) were the dominan

10 Disorganized activity (Endo: 41.3% versus Epi: 46.8%, P=0.0194) and single wave

11 referentially polymerized l-lactide, whereas endo-6 preferred d-lactide as the substrate.

12 o-3,5-diphenylpyrrolidine-2-carboxylic acid (endo-6) and (2S,3S,4R,5S)-1-methyl-4-nitro-3,5-diphenylp

13 here that Rad23 can bind Ho-endonuclease (Ho-endo), a nuclear protein that initiates mating-type swit

14 ses derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could not recognize triantennary N-g

15 ional assays, we demonstrate that Ega3 is an endo-acting alpha-1,4-galactosaminidase whose activity d

16 scribe the discovery and characterisation of endo-acting enzymes from prominent mucin-degrading bacte

17 galactosyl substitution and was shown to be endo-acting generating a more diverse mixture of oligosa

18 iveness of this array for detecting exo- and endo-acting glycoside hydrolase activity using commercia

19 do-alpha-1,2-mannosidase (MANEA) is the sole endo-acting glycoside hydrolase involved in N-glycan tri

20 hat the bacterium expressed a single-surface endo-acting lyase that cleaved HS, reflecting its higher

21 urther demonstrate that the Rpfs function as endo-acting lytic transglycosylases, cleaving within the

22 ne stereoisomer in agreement with the known "endo-alkyl rule".

23 med by a stereoselectivity controlled by the endo-alkyl rule.

24 ix[2]pseudorotaxane, namely, endo-benzyl and endo-alkyl, are formed by a stereoselectivity controlled

25 saccharide inhibitors, their binding to GH99 endo-alpha-1,2-mannanases, and their structural analysis

26 Endo-alpha-1,2-mannosidases and endo-alpha-1,2-mannanases, members of glycoside hydrolas

27 Endo-alpha-1,2-mannosidase (MANEA) is the sole endo-acti

28 Endo-alpha-1,2-mannosidases and endo-alpha-1,2-mannanase

29 ts revealed that both proteins are retaining endo-alpha-1,4-N-acetylgalactosaminidases with a minimal

30 GAS secretes EndoS, an endoglycosidase that specifically cleaves the

31 ng veterinary practice to reduce the load of endo and ectoparasites, but has the potential to be adde

32 Simultaneous intraoperative mapping of endo- and epicardial lateral right atrium wall was perfo

33 W indicate that muscular connections between endo- and epicardium underlie EBW and that a slight degr

34 earch has been applied to design a series of endo- and exo-3-(pyridin-3-yl)bicyclo[2.2.1]heptan-2-ami

35 ell-suited to generate diversity at both the endo- and exo-cyclic fragments formed during the ring-cl

36 We used endo- and exo-metabolomics data to show that the thermod

37 Both endo- and exo-ring-protonated isomers are calculated to

38 14 patients with severe developmental delay, endo- and exocrine dysfunction, impairment of the sensor

39 the sensory and autonomic nervous system and endo- and exocrine glands.

40 zoidal-shaped Ag(5) moiety via Ag-N bonds to endo- and exocyclic nitrogens of cytosine and adenine.

41 king along microtubules and through the cell endo- and exocytic pathways can be next visualized via l

42 AnxA6), regulates membrane trafficking along endo- and exocytic pathways.

43 We compared synaptic vesicle proteins, endo- and exocytosis cofactors, cytoskeleton components,

44 ave been developed to study the formation of endo- and exogenous DNA adducts.

45 Artemis is a vertebrate nuclease with both endo- and exonuclease activities that acts on a wide ran

46 However, some noncoding RNA classes use endo- and exonucleases to achieve functionality.

47 l cells, is catalyzed by specific subsets of endo- and exoribonucleases that together recycle RNA fra

48 annihilation and that this is true for both endo- and exothermic singlet fission materials.

49 conjugation of reduced glutathione (GSH) to endo- and xenobiotics.

50 ancy under natural conditions, namely para-, endo-, and ecodormancy in summer, fall, and winter, resp

51 er was generated through an intramolecular 7-endo attack of a silyl-tethered allyl moiety on a tertia

52 entations of calix[2]pseudorotaxane, namely, endo-benzyl and endo-alkyl, are formed by a stereoselect

53 Endo-beta(1 -> 4)-mannanases (endomannanases) catalyse d

54 the -3 subsite and turns the enzyme into an endo-beta(1,4)-glucanase.

55 ystem, KORRIGAN1 (KOR1), a membrane-anchored endo-beta-1,4-glucanase involved in cellulose biosynthes

56 elevant glycosyl hydrolases, a putative GH10 endo-beta-1,4-xylanase, Xyl10E, was cloned and expressed

57 and human NK cells express low levels of the endo-beta-D-glucuronidase heparanase that increase upon

58 The delivery of heparanase, the endo-beta-D-glucuronidase that degrades HS, accelerated

59 Importantly, endo-beta-galactosidase coupled with MALDI-MS allowed th

60 (GH74) is a historically important family of endo-beta-glucanases.

61 e conformer adopts a nearly synperiplanar Pd/endo-beta-H arrangement, whereas for the analogous Pd si

62 of the five-membered lactone the smallest Pd/endo-beta-H dihedral angle is observed for a conformer w

63 Aspergillus quadrilineatus endo-beta-mannanase effectively degraded konjac glucoman

64 EndoBT-3987 is a key endo-beta-N-acetylglucosaminidase (ENGase) that initiate

65 The endo-beta-N-acetylglucosaminidases (ENGases) are an enzy

66 8 is an exo-beta1,3-glucanase and Eng1 is an endo-beta1,3-glucanase.

67 der reactions of trans-cyclooctene (TCO) and endo-bicyclo[6.1.0]nonyne (BCN) with a 1,2,4,5-tetrazine

68 Cs, and Bi, to probe the utility of the exo/ endo cages as host-guest systems.

69 tein (LDL) from UNx rats with normal EPI and ENDO cardiomyocytes recapitulated the electrophysiologic

70 current (Ito) in EPI but not in endocardial (ENDO) cardiomyocytes of UNx rats led to a decreased tran

71 roliferation and -migration observed in LKB1(endo-/-) cells.

72 te mRNA decay, avoiding the buildup of toxic endo-cleaved mRNA decay intermediates.

73 bose sugar pucker equilibrium toward the C3'-endo conformation formed in canonical duplexes.

74 midal species (Pb(II)S3 and As(III)S3) in an endo conformation oriented toward the 3SCC C-termini, wh

75 between non-helical (C2-endo) to helical (C3-endo) conformations during formation of two distinct exc

76 o a highly reactive, S = 1/2 ring-protonated endo-Cp*H-Fe relative, triggered by the addition of CO.

77 formations involved chloride-ion-triggered 6-endo cyclization of o-alkynylisocyanobenzenes to generat

78 es and relative free energies of 5-exo and 6-endo cyclization pathways support that the 5-exo cycliza

79 atalyzed radical cyclization, and a double 6-endo cyclization with catalyst loadings as low as 0.01 m

80 a d-xylofuranose precursor, [I(+)]-induced 6-endo cyclization, and 1,2-trans stereoselective glycosyl

81 peptides confirmed preferential formation of endo cycloadduct stereochemistry, imparting significant

82 igands produces diastereodivergently exo- or endo-cycloadducts, respectively.

83 ndoglycosidases derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could not recognize tria

84 highly functionalized cyclohexenes with high endo diastereoselectivity.

85 We report here the regioselective 6-endo-dig cyclization of [2-(butylselanyl)phenyl]propynol

86 zations with tryptamine, a metal-promoted 6- endo-dig cyclization of an enyne to establish the second

87 ied for the enantioselective 5-exo-dig and 6-endo-dig cyclization of different 1,6-enynes as well as

88 he methodology involved the regioselective 6-endo-dig cyclization of thiopropargyl benzimidazoles pro

89 oach is a regioselective gold(I)-catalyzed 6-endo-dig cyclization strategy for the construction of th

90 efficiently catalyzes the highly selective 6-endo-dig cyclization, completely reversing the regiochem

91 g alpha-amino ynone generation followed by 6-endo-dig cyclization.

92 The synthesis relies on gold-catalyzed 6-endo-dig hydroarylation of an unusual enynol substrate a

93 hydropyrans can be obtained by a selective 6-endo-dig iodocyclization, whereas gold-catalyzed 5-exo-d

94 ctively through an initial intramolecular 5- endo-dig mode with two new carbon-selenium bonds formati

95 ple bond, and cyclization via an exclusive 6-endo-dig process.

96 ion is a 4pai-electrocyclization and not a 5-endo-dig ring closure as had been proposed in the litera

97 thylsilyl chloride (TMSCl), which leads to 6-endo-dig-selective chlorinative annulation to give the d

98 ls-Alder cyclisation of NBD into its exo-cis-endo dimer.

99 ee distinct hydrolytic modes of action: exo, endo-dissociative, and endo-processive.

100 neous endo-epi phase mapping to characterize endo-epi activation patterns on long segments of human p

101 s phase difference of >=20 ms between paired endo-epi electrodes.

102 Simultaneous endo-epi phase mapping of prolonged human persistent AF

103 In the current study, we used simultaneous endo-epi phase mapping to characterize endo-epi activati

104 Endo-Epi wavefront patterns were simultaneously compared

105 Endo-epicardial asynchrony may play a major role in the

106 ium underlie EBW and that a slight degree of endo-epicardial asynchrony required for EBW to occur is

107 the arrhythmogenic substrate and result from endo-epicardial asynchrony, which also occurs to some de

108 ing and dichotomously defined by a hyperemic endo-epicardial gradient <1.0.

109 rence Network for Rare Endocrine Conditions (Endo-ERN), and provide recommendations for future resear

110 are key to reliably assigning the Cp*( exo/ endo-eta(4)-C(5)Me(5)H)Co(+) species.

111 ion of the ring-protonated isomers Cp*( exo/ endo-eta(4)-C(5)Me(5)H)Co(+).

112 gnment as the ring-protonated isomer, [Fe(I)(endo-eta(4)-Cp*H)(dppe)(CO)](+).

113 Discrete endo,exo-norbornenyl dialkylesters (dimethyl DME, diethy

114 However, its aggressive endo-/exo-nuclease activities make MNase-seq unreliable

115 ethylene-1,2,4-naphthotriones, such as small endo/exo diastereoselectivity, as well as pronounced ort

116 , with their affinity being dependent on the endo/exo isomerism and on the methylation degree of the

117 termediates, and this study corroborated the endo/exo ratio and the mechanistic pathway with key inte

118 well as the origin of the observed switched endo/exo ratios, are also explained by means of density

119 d to investigate the factors influencing the endo/exo selectivity.

120 ace adhesion receptors that are modulated by endo-exocytic trafficking, but existing tools to study t

121 ntegrin function is dynamically modulated by endo-exocytic trafficking, however, major mysteries rema

122 Alterations of endo/exocytic proteins have long been associated with ma

123 g on the mechanisms underlying the impact of endo/exocytic proteins in cancer, a scenario emerges in

124 ction, in terms of, e.g., cellular adhesion, endo/exocytosis, cellular uptake, and mechanosensing.

125 agellum, which is an important organelle for endo/exocytosis.

126 The Endo-F3 mutants represent the first endoglycosidase-base

127 The Endo-F3 mutants were able to use both bi- and triantenna

128 olecular Stetter reaction proceeding via the endo-fashion was the key step for the transition-metal-f

129 e other systems displaying different exo and endo functionalities within the cage assembly were gener

130 the 90 degrees Pt(II) heteroligation of the endo-functionalized double-bridged tweezer bearing pyrid

131 hen compared to batch production with a pure endo-galacturonase enzyme, demonstrating its feasibility

132 different families, including a CNG-specific endo-glycosidase activity.

133 nstrate for the first time that full length, Endo H in vivo enzymatic deglycosylated Pfs48/45 antigen

134 Thus, Endo H in vivo enzymatic deglycosylated Pfs48/45 is a pr

135 cosidase F (PNGase F) and endoglycosidase H (Endo H).

136 nhibitor kifunensine and the endoglycosidase Endo H, and intramuscularly immunized mice to examine it

137 istance to phagocytic killing of GAS lacking EndoS in vitro and decreased virulence in a mouse model

138 This protocol, based on the 5-endo iodocyclization reaction of o-(alkynyl)styrenes, re

139 New endo-leaks were associated with increased aneurysm size

140 + ATPase (V-ATPase), the key proton pump for endo-lysosomal acidification, and two previously unchara

141 in-dependent tagging and degradation through endo-lysosomal and autophagy pathways.

142 Finally, we find that different endo-lysosomal Ca(2+) channels play diverse roles, with

143 kably, phagocytosis is driven by these local endo-lysosomal Ca(2+) nanodomains rather than global cyt

144 ECs internalized myelin, which was routed to endo-lysosomal compartment for processing in a time-depe

145 at once cleaved, the drug escapes the acidic endo-lysosomal compartment into the cytosol and traffics

146 the life span, the RPE develops an expanded endo-lysosomal compartment to maintain the high efficien

147 ization of the NDP receptor complex into the endo-lysosomal compartment.

148 e is the most prevalent nuclease activity in endo-lysosomal compartments and that additional stabiliz

149 e majority of dendrimers are directed to the endo-lysosomal compartments in both cell types.

150 holesterol efflux from cellular membrane and endo-lysosomal compartments, reduces lysosomal lipid acc

151 zyme YOD1, which we term ELDR components for Endo-Lysosomal Damage Response.

152 ithin Sac1(ts) retinal cells due to impaired endo-lysosomal degradation.

153 This study suggests that endo-lysosomal impairment in neurons might play an impor

154 Interestingly, cells with endo-lysosomal membrane permeabilization (LMP) are more

155 lphaS pathology with galectin-3 (a marker of endo-lysosomal membrane rupture) in the basal forebrain

156 ing entry is independent of the conventional endo-lysosomal network.

157 tination and degradation through proteasome, endo-lysosomal or autophagy-related pathways.

158 The low-level endo-lysosomal signaling lipid, phosphatidylinositol 3,5

159 phagy modulators that do not perturb general endo-lysosomal traffic possesses unique challenges.

160 We recently revealed that the late endo-lysosomal transporter ATP13A2 pumps polyamines like

161 r sorting and degradation pathways involving endo-lysosomal vesicles, the ubiquitin-proteasome system

162 that PorB increases the level of OVA in the endo-/lysosomal cellular compartment of BMDCs, increases

163 n of sFceRI requires Src phosphorylation and endo/lysosomal acidification.

164 g it could enhance viral survival in hostile endo/lysosomal compartments.

165 To enhance bioavailability and improve endo/lysosomal escape of siRNA, we designed pH-activated

166 Caveolin-1 associates with the endo/lysosomal machinery of cells in culture, suggesting

167 mammalian TPC channels have been shown to be endo/lysosomal Na(+)-selective or Ca(2+)-release channel

168 r vesicular trafficking, immune response and endo/lysosomal processes.

169 man cells, we visualized alphaS aggregation, endo-lysosome distribution, and endo-lysosome rupture in

170 phagosomes to promote phagocytosis, whereas endo-lysosome immobilization prevents it.

171 endocytosis-mediated seeding associated with endo-lysosome rupture and have significantly reduced see

172 aggregation, endo-lysosome distribution, and endo-lysosome rupture in real-time.

173 D, but not in age-matched controls, suggests endo-lysosome rupture is involved in the formation of al

174 plasma membrane or via endocytosis-mediated endo-lysosome rupture, leading to formation of endo-lyso

175 eading to formation of endo-lysosome-free or endo-lysosome-associated alphaS aggregates, respectively

176 do-lysosome rupture, leading to formation of endo-lysosome-free or endo-lysosome-associated alphaS ag

177 with other proteins that function at the ER-endo/lysosome interface in coordinating endocytic flow w

178 Here, we reveal that endo-lysosomes act as platforms for a new phagocytic sig

179 digested phagocytic material inside enlarged endo-lysosomes and as a result, hemotin mutants have red

180 eus after acid-triggered drug release in the endo-lysosomes.

181 rom abnormal cholesterol accumulation in the endo/lysosomes.

182 ported endoglycosidases derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could not recogn

183 dosperm-specific maternally expressed genes (endo-MEGs) were associated with maternally preferred H3K

184 Around the transcription start sites of endo-MEGs, DNA methylation and H3K4me3 specifically mark

185 same allele-specific epigenetic features as endo-MEGs, indicating similar mechanisms for the regulat

186 ge one was characterised by up-regulation of endo-metabolites such as ferricrocin, fatty acids and fl

187 Tumors implanted in LKB1(endo-/-) mice but not macrophage-specific LKB1-knockout

188 thelial cells but not in macrophages in LKB1(endo-/-) mice.

189 ndothelial cell-specific LKB1-knockout (LKB1(endo-/-)) mice by crossbreeding vascular endothelial-cad

190 uents were recently found to ring close in 5-endo mode by addition to the oxygen atoms of the ester s

191 e O atoms of their distal ester groups in 5- endo mode to yield 1,2-oxaborole radicals.

192 ion and thereby verifies the hypothesis that EndoS modifies antibodies in vivo.

193 Consistently, LKB1(endo-/-) mouse tissues including the lung, skin, kidney

194 Endothelial-to-mesenchyme-like transition (Endo-MT) of trabecular meshwork (TM) cells is known to b

195 ates and confounds the pathology by inducing Endo-MT-like changes in the TM.

196 though active zone (AZ) number is doubled in endo mutants, a compensatory reduction in their size hom

197 cess, we investigated Drosophila endophilin (endo) mutants.

198 Upon IL-6 treatment, Endo-N and Endo-T cells displayed altered expression of

199 itutively, compared with normal endothelial (Endo-N) cells, Endo-T cells differentially expressed DNA

200 liminated by the polySia-specific sialidase, Endo-NF.

201 roceed a selective C-N bond formation at the endo-nitrogen of 2-aminoheteroarenes followed by an intr

202 selectivity of N(6)-dicyclopropylmethyl and endo-norbornyladenosines but increased ribavirin selecti

203 Human endo-O-sulfatases (Sulf-1 and Sulf-2) are extracellular

204 These endo-O-sulfatases are transported onto the cell surface

205 he effect of monomer stereochemistry (exo vs endo) of two types of ester substituted monomers was als

206 Calix[6]arenes bearing endo-OH functions give rise to a less efficient threadin

207 pectrometry, we characterized the effects of EndoS on host IgG glycosylation during the course of inf

208 Four adducts, presenting an endo or exo configuration and proximal or distal geometr

209 ained in the pyrrolo ring (saturated or with endo or exo unsaturations), a key feature determining th

210 less efficient threading with respect to the endo-OR ones, in line with what was known from the compl

211 The process occurred on a 5-exo versus 6-endo pathway depending on the substitution of the alkyny

212 enabling oxyamination via either 5-exo or 6-endo pathways.

213 +) led to the toposelective formation of the endo-pentylpseudorotaxane stereoisomer in agreement with

214 Ser-type (S9D) peptidase with both exo- and endo-peptidase activity.

215 endo-peptidases act first followed by the successive act

216 extensively hydrolysed firstly by endogenous endo-peptidases followed by the successive action of exo

217 osed by a homogalacturonan unit linked to an endo-PG resistant unit.

218 o illustrate the genotypic underpinnings of (endo)phenotypic diversity.

219 discussion, we address genomic context and (endo)phenotypic heterogeneity, and examine commonly enco

220 ports Ca(2+) from the cytosol into the sarco(endo)plasmic reticulum (SR/ER) lumen, driven by ATP.

221 concentration, including those in the sarco(endo)plasmic reticulum [S(E)R], are primarily coordinate

222 (SPCA1a/2) are closely related to the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) and are imp

223 The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) is a P-type

224 aximal turnover rate than the purified sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1a).

225 l ankyrin 1 (sAnk1) interacts with the sarco(endo)plasmic reticulum Ca(2+)-ATPase in skeletal muscle

226 SERCA1, the sarco(endo)plasmic reticulum Ca(2+)-ATPase of skeletal muscle,

227 The transport activity of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in cardiac

228 SERCA [sarco(endo)plasmic reticulum calcium ATPase] is regulated by o

229 ns from strawberry fruits were digested with endo-polygalacturonase M2 from Aspergillus aculeatus and

230 The endo primary amines displayed the lowest K(i) values on

231 substituted N-allylanilines via an unusual 6-endo process has been developed.

232 ol of the regioselectivity in favor of the 6-endo process.

233 modes of action: exo, endo-dissociative, and endo-processive.

234 llylic ring expansion to yield the formal "6-endo" products with aromatization via stereoelectronical

235 Our previous study has shown that endo-Protoporphyrin IX based SDT (ALA-SDT) could induce

236 preclinical evidence for a role of FOXA1 in Endo-R breast cancer as well as evidence for its clinica

237 ty, reaching complete branched/linear or exo/endo ratios and excellent diastereo- and enantiomeric ex

238 We observed that the degradation of Ho-endo required export from the nucleus, in agreement with

239 chloroplast RNase J displaces both exo- and endo-ribonucleolytic activities and contains a unique GT

240 At the onset of endocycle S (endo-S) phase, H1 is heavily and specifically loaded int

241 ously reported endoglycosidases derived from Endo-S, Endo-M, Endo-D, and Endo-A mutants that could no

242 from Streptococcus pyogenes of serotype M49 (Endo-S2) and the evaluation of the resulting mutants for

243 ne conductance regulator (CFTR) expressed on endo(sarco)plasmic reticulum.

244 osphate receptor (IP3R), thereby linking the endo-/sarcoplasmic reticulum to the plasma membrane.

245 hapsigargin, a subnanomolar inhibitor of the endo/sarcoplasmic calcium ATPase (SERCA), is presented.

246 re calcium (Ca(2+) ) release channels on the endo/sarcoplasmic reticulum (ER/SR).

247 f stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum Ca(2+) sensor.

248 The sequences feature highly endo-selective [2 + 2]-photocycloaddition reactions foll

249 nd Matsuda-Heck coupling, which proceeds via endo-selective beta-H-elimination to give diarylmethyl-s

250 The reaction is endo-selective in the presence of Lewis acid catalyst.

251 A scalable endo-selective synthesis of 2,3,4,5-tetrasubstituted pyr

252 Endo selectivity is predicted for both uncatalyzed and c

253 lding block shows that the commonly accepted endo selectivity, ruled by controversial secondary orbit

254 nding highly substituted pyrrolizidines with endo selectivity.

255 The exo- or endo-selectivity of bicyclic scaffolds depends on the se

256 tured S2 cells that synthetic repeat-derived endo-siRNA mimics are sufficient to rescue Dcr-2-deficie

257 elegans, we reveal an unprecedented role for endo-siRNA molecules in the maintenance of proteostasis

258 Furthermore, we identify an endo-siRNA-regulated tyrosine phosphatase, which limits

259 This establishes a role for endo siRNAs in the aging process and identifies downstre

260 ological processes that are regulated by the endo siRNAs to affect longevity.

261 , nuclear RNAi ensures robust inheritance of endo-siRNAs and deposition of repressive H3K9me3 marks a

262 esis, regulation, and function of C. elegans endo-siRNAs and piRNAs, along with recent insights into

263 Altogether, our findings point to endo-siRNAs as a link between germline removal and the H

264 However, in contrast to miRNAs, the role of endo-siRNAs in aging remains unexplored.

265 a crucial function of paternal miRNAs and/or endo-siRNAs in the control of the transcriptomic homeost

266 deps-1 mutants fail to produce the secondary endo-siRNAs required for the silencing of piRNA targets.

267 interfering RNAs (endo-siRNAs) revealed that endo-siRNAs that depend on SET-25 and SET-32 target newl

268 ed RNAs are also known to give rise to small endo-siRNAs to help maintain heterochromatin at their si

269 including endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), drive t

270 types of endogenous small interfering RNAs (endo-siRNAs) produced by RNA-dependent RNA polymerase (R

271 heritable endogenous small interfering RNAs (endo-siRNAs) revealed that endo-siRNAs that depend on SE

272 expressed endogenous small interfering RNAs (endo-siRNAs) transmit multigenerational epigenetic infor

273 RNAs) and endogenous small-interfering RNAs (endo-siRNAs), are key gene regulators in eukaryotes, pla

274 mutant deficient in RdRP-produced secondary endo-siRNAs, the silencing histone mark H3K9me3 is large

275 ational fertility and acts as an effector of endo-siRNAs.

276 to ERalpha, which unequivocally corroborated endo stereochemistry of the resulting Diels-Alder adduct

277 ion and backbone substitution either exo- or endo-stereoisomers were formed selectively with up to a

278 ine substituted cytidines, we show that a 2'-endo sugar conformation of the target deoxycytidine is f

279 n angle and all three strands favoring a C3'-endo sugar pucker.

280 Duplex RNA segments have A-form C3' endo sugar puckers but widened major groove widths, givi

281 oglycan metabolic pathways; understanding of endo sulfatase activity questioning the paradigm of how

282 a paradox in the functioning of prokaryotic (endo)symbionts.

283 and fungal determinants involved in ecto to endo symbiotic switch that occurs in desert truffle unde

284 ared with normal endothelial (Endo-N) cells, Endo-T cells differentially expressed DNA methyltransfer

285 Upon IL-6 treatment, Endo-N and Endo-T cells displayed altered expression of the DNA met

286 Tumor endothelial (Endo-T) cells in 3D cultures exhibited higher VEGFR2 exp

287 mpanying transitions between non-helical (C2-endo) to helical (C3-endo) conformations during formatio

288 these stress-associated signals induced the endo- to ecodormancy transition and growth competence.

289 When crown buds transitioned from endo- to ecodormancy, the ABA metabolites PA and DPA dec

290 amework with the participation of xyloglucan endo-transglycosylase/hydrolases (XTHs).

291 ommittee due to the early termination of the ENDO trial (NCT01728116) by the US Food and Drug Adminis

292 retro-3-exo path is faster than the direct 6-endo-trig closure, revealing the general exo-preference

293 lkylpiperidines has been developed using a 6-endo-trig cyclization of (E)-enones.

294 e absence of any reagent in a cascade SN2'-6-endo-trig fashion and is completely regioselective and h

295 on of benzothiazole-2-carboxylates via the 5-endo-trig process contrary to Baldwin's rule.

296 ntrol surveillance of a SNARE protein in the endo-vacuolar system.

297 Additional endo-vascular procedures within two years of observation

298 within plant microbiomes, i.e., endophytes ("endo" = within, "phyte" = plant), can significantly modi

299 em containing (U/gds) beta-mannanase (1021), endo-xylanase (1 9 1), alpha-galactosidase (3.42), beta-

300 Endo-xylanase action on pretreated wheat chaff released