ライフサイエンスコーパス: endobiotic

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1 rimary role in acute responses to this toxic endobiotic.

2 aged in the metabolism of numerous xeno- and endobiotics.

3 metabolic activation of both xenobiotics and endobiotics.

4 e uptake and secretion of cationic drugs and endobiotics.

5 he hydroxyls and primary amines of xeno- and endobiotics.

6 We investigated the endobiotic and hepatic role of AHR in fatty liver and en

7 Mammalian systems inactivate endobiotic and xenobiotic compounds by linking them to a

8 receptor that regulates enzymes involved in endobiotic and xenobiotic metabolism.

9 n species, electrophiles, and other reactive endobiotic and xenobiotic metabolites.

10 ely involved in clearing potentially harmful endobiotic and xenobiotic OAs from the eye.

11 minate by glucuronidation a broad variety of endobiotic and xenobiotic substrates, which include bili

12 d by an impaired metabolic detoxification of endobiotics and a persistent microbial-induced immune re

13 for the metabolism and secretion of numerous endobiotics and drugs.

14 ontrol glucose production, detoxification of endobiotics and xenobiotics, and the regulation of prost

15 etion and lipophilicity) of a broad range of endobiotics and xenobiotics, which could plausibly have

16 nzyme involved in the metabolism of multiple endobiotics and xenobiotics.

17 hat catalyse the glucuronidation of numerous endobiotics and xenobiotics.

18 ification and elimination of xenobiotics and endobiotics by modulating the expression of genes encodi

19 metabolism and excretion of xenobiotics and endobiotics by regulating the expression of drug-metabol

20 enosensors postulated to alleviate xeno- and endobiotic chemical insults.

21 zes a range of potentially harmful drugs and endobiotic chemicals but must complex with the nuclear r

22 the conjugation of lipophilic exobiotic and endobiotic compounds, which leads to the excretion of hy

23 abolism of a wide spectrum of xenobiotic and endobiotic compounds.

24 play a central role in processing a range of endobiotic compounds.

25 eptor (CAR) are implicated in xenobiotic and endobiotic detoxification, including the clearance of to

26 Interestingly, the endobiotic estradiol-17-glucuronide and the xenobiotic i

27 ndrostane receptor (CAR) modulates xeno- and endobiotic hepatotoxicity by regulating detoxification p

28 re important in the elimination of xeno- and endobiotics, including the natural biladienone pigment b

29 ane X receptor (PXR) mediates xenobiotic and endobiotic metabolism as well as hepatocyte proliferatio

30 siological regulation of both xenobiotic and endobiotic metabolism.

31 r (CAR) is a key regulator of xenobiotic and endobiotic metabolism.

32 xpression of genes central to xenobiotic and endobiotic metabolism.

33 and is involved in xenobiotic processing and endobiotic metabolism.

34 uman carboxylesterase 1 (hCE1) is a drug and endobiotic-processing serine hydrolase that exhibits rel

35 oss-talk and the hierarchy of xenobiotic and endobiotic regulation.

36 In this study, we show that PXR plays an endobiotic role by impacting lipid homeostasis.

37 The goal of this study was to determine the endobiotic role of AhR in hepatic steatosis.

38 this study, we have uncovered an unexpected endobiotic role of PXR in obesity and type 2 diabetes.

39 response to potentially toxic xenobiotic and endobiotic stimuli.

40 or of coordinate responses to xenobiotic and endobiotic stress.

41 in the coordinate response to xenobiotic and endobiotic stress.

42 o conjugate xenobiotics, including drugs and endobiotics such as metabolic byproducts, hormones, and

43 epatic metabolism of therapeutics as well as endobiotics such as steroid hormones.

44 bile formation, intermediary metabolism, and endobiotic/xenobiotic detoxification.

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