ライフサイエンスコーパス: endocrine pancreas

1 letal muscle, adipose tissue, brain, and the endocrine pancreas.

2 cellular punctate structures in cells of the endocrine pancreas.

3 s highly enriched for genes expressed in the endocrine pancreas.

4 epositing as cytotoxic amyloid fibers in the endocrine pancreas.

5 localized to the islets of Langerhans of the endocrine pancreas.

6 egral role in the regulatory pathways of the endocrine pancreas.

7 ular space surrounding the beta-cells of the endocrine pancreas.

8 ely localized to beta cells within the adult endocrine pancreas.

9 nical disease was evident in the exocrine or endocrine pancreas.

10 gs of the pineal gland, adenohypophysis, and endocrine pancreas.

11 n the normal development and function of the endocrine pancreas.

12 ligands to morphogenetic events in the human endocrine pancreas.

13 nd insulin secretion in the beta-cell of the endocrine pancreas.

14 liver, adipose tissue, blood cells, and the endocrine pancreas.

15 nsulin and glucagon) was used to control the endocrine pancreas.

16 of the insulin gene in the beta-cells of the endocrine pancreas.

17 glucagon infusions) was used to control the endocrine pancreas.

18 glucagon infusions) was used to control the endocrine pancreas.

19 adipose tissue regulates alpha-cells in the endocrine pancreas.

20 ve imaging of the serotonergic system in the endocrine pancreas.

21 ould therefore be used to estimate the human endocrine pancreas.

22 al nervous systems, olfactory epithelium and endocrine pancreas.

23 l noninvasive surrogate marker for the human endocrine pancreas.

24 ating insulin release from beta cells of the endocrine pancreas.

25 ring system that continuously reports on the endocrine pancreas.

26 eters to assess the functional status of the endocrine pancreas.

27 an important player in the physiology of the endocrine pancreas.

28 he regulation of insulin secretion by the CF endocrine pancreas.

29 mental processes in the brain as well as the endocrine pancreas.

30 P1B and TCPTP in regulating ER stress in the endocrine pancreas.

31 rphological changes in both the exocrine and endocrine pancreas.

32 ERO1-beta is greatly enriched in the endocrine pancreas.

33 ocrine environment for MEN1 tumorigenesis in endocrine pancreas.

34 ors primarily in parathyroid, pituitary, and endocrine pancreas.

35 rograms that regulate the development of the endocrine pancreas.

36 y acting in peripheral tissues including the endocrine pancreas.

37 , we further explored the role of MCH in the endocrine pancreas.

38 derm that directly induces precursors of the endocrine pancreas.

39 regenerative medicine-inspired bioartificial endocrine pancreas.

40 inst the insulin-producing beta cells of the endocrine pancreas.

41 specific functions in the development of the endocrine pancreas.

42 -p48 in the development of both exocrine and endocrine pancreas.

43 opment and for proper differentiation of the endocrine pancreas.

44 rare transcripts expressed in the mammalian endocrine pancreas.

45 eneration, fully human-derived bioartificial endocrine pancreas.

46 is the major site of K(ATP) channels of the endocrine pancreas.

47 ergy metabolism in the liver, intestine, and endocrine pancreas.

48 gh levels in the islets of Langerhans of the endocrine pancreas.

49 its function in different organs such as the endocrine pancreas, adipose tissue, skeletal muscle, and

50 In the endocrine pancreas, alpha-cell-specific expression of th

51 -like environment guiding the genesis of the endocrine pancreas and advance current models for how di

52 PERK, are associated with dysfunction of the endocrine pancreas and diabetes.

53 ring gestation alters the development of the endocrine pancreas and favors the occurrence of T2D late

54 rentiation along new lineages, production of endocrine pancreas and insulin-secreting beta cells from

55 on of ATF3 in the pancreas leads to abnormal endocrine pancreas and reduced numbers of hormone-produc

56 esponse in promoting adaptive changes in the endocrine pancreas and suggests that enhancement of this

57 c development of the exocrine but not of the endocrine pancreas and that defects of Igf1r do not alte

58 le of NEUROD1 in both the development of the endocrine pancreas and the central nervous system in hum

59 established between growth of the embryonic endocrine pancreas and the islet cell replication that o

60 alone is sufficient to induce tumors in the endocrine pancreas and thymus.

61 y multiple tumors in the parathyroid glands, endocrine pancreas, and anterior pituitary.

62 the stem cell layer of stratified epithelia, endocrine pancreas, and thymic medulla, with a pattern t

63 d Dnmt1, as differentiation of the liver and endocrine pancreas appeared normal.

64 Neoplasms of the endocrine pancreas are extremely rare, and molecular mec

65 ation of interstitial fluid transport in the endocrine pancreas as well as for the pathophysiology of

66 Aqp7 only, not that of Aqp3 or Aqp9, in the endocrine pancreas at both the mRNA (by reverse transcri

67 ympathetic activity defines a nervous system/endocrine pancreas axis that is critical for beta cell m

68 dantly in adipose tissue, the brain, and the endocrine pancreas but scarcely in the exocrine pancreas

69 ntagonizing RA-mediated specification of the endocrine pancreas, but continues to promote differentia

70 effort was made to enrich for cDNAs from the endocrine pancreas by constructing libraries from isolat

71 depolarization, or insulin were assessed by endocrine pancreas cDNA microarrays.

72 Making endocrine pancreas cells at will is one of the major goa

73 tal development, cyclin D2 expression in the endocrine pancreas coincides with the replication of end

74 Neoplasms of the endocrine pancreas, commonly referenced as pancreatic is

75 The Endocrine Pancreas Consortium was formed in late 1999 to

76 Trans-differentiation into endocrine pancreas could have significant implications f

77 The exocrine and endocrine pancreas developed normally in Perk-/- mice.

78 orally delineate the role of Hh in zebrafish endocrine pancreas development and investigate its relat

79 the expression of multiple genes related to endocrine pancreas development and islet function in the

80 We conclude that NEUROG3 is essential for endocrine pancreas development in humans and that as lit

81 analyses implicate new signaling pathways in endocrine pancreas development, and identified sets of k

82 estion whether NEUROG3 is required for human endocrine pancreas development.

83 from four biologically significant stages of endocrine pancreas development: endoderm before pancreas

84 r cells that differentiate into exocrine and endocrine pancreas did not affect normal pancreas morpho

85 ly affecting the parathyroid, pituitary, and endocrine pancreas, due to the inactivation of the MEN1

86 density and pericyte distribution within the endocrine pancreas; expression of angiogenic factors was

87 urogenin3 functions as a master regulator of endocrine pancreas formation, and its deficiency leads t

88 humans with NEUROG3 mutations are born with endocrine pancreas function, calling into question wheth

89 The incidence of delayed endocrine pancreas graft function and its impact on long

90 n order to decrease the incidence of delayed endocrine pancreas graft function and its negative impac

91 The incidence of delayed endocrine pancreas graft function was 69%.

92 Delayed endocrine pancreas graft function was defined as total,

93 ilar for recipients without and with delayed endocrine pancreas graft function.

94 recognized evidence of a mechanism governing endocrine pancreas growth and function.

95 on of these isoforms within the exocrine and endocrine pancreas has not been explored in detail.

96 The vertebrate endocrine pancreas has the crucial function of maintaini

97 t that some regenerative capabilities of the endocrine pancreas have been documented and recent resea

98 f the genes that regulate development of the endocrine pancreas have been identified, comparatively l

99 We report here that within the adult endocrine pancreas, Hhex is selectively expressed in the

100 OXA is also found in the endocrine pancreas; however, little is known about its r

101 ustrating the regenerative capability of the endocrine pancreas in addition to advances in stem cell

102 id not discriminate between the exocrine and endocrine pancreas in control animals, whereas autoradio

103 ption factor required for development of the endocrine pancreas in mice.

104 o signal in differentiated beta-cells of the endocrine pancreas in regulating insulin production.

105 Development of the endocrine pancreas includes a series of early events whe

106 that ARC protein is abundant in cells of the endocrine pancreas, including >99.5% of mouse and 73% of

107 In addition, the endocrine pancreas, intrapancreatic nerves, and some ext

108 The endocrine pancreas is comprised of beta and alpha cells

109 The endocrine pancreas is organized into clusters of cells c

110 A lineage tree of the developing endocrine pancreas is outlined to further illustrate thi

111 The endocrine pancreas is particularly sensitive to the type

112 s; however, the later differentiation of the endocrine pancreas is uniquely dependent upon high PDX1

113 aling functions in the fully developed adult endocrine pancreas is unknown.

114 ucagon is secreted by the alpha-cells of the endocrine pancreas (islets of Langerhans) during fasting

115 nic development and adult homeostasis of the endocrine pancreas, little is known about what regulates

116 mice fed VAD diets display remodeling of the endocrine pancreas, marked beta-cell apoptosis, shifts t

117 uced the expression of peptide YY, the early endocrine pancreas marker.

118 ical targets differentially activated in the endocrine pancreas of Men1 mice and highlight the need f

119 e that forms cytotoxic amyloid fibers in the endocrine pancreas of patients with type II diabetes (NI

120 also identified developmental changes in the endocrine pancreas of Snord116p-/m+ animals that persist

121 Serotonergic biosynthesis in the endocrine pancreas, of which the islets of Langerhans is

122 doderm to control cell fate decisions in the endocrine pancreas progenitor lineage.

123 ols pancreas organogenesis, specification of endocrine pancreas progenitors, and the postnatal growth

124 genic mice revealed abnormalities within the endocrine pancreas, ranging from pancreatic islet hyperp

125 ional program also contained products of the endocrine pancreas (Reg-1 and insulin genes) and the exp

126 4a), resulting in limited capacity for adult endocrine pancreas regeneration.

127 was greater than in islets isolated from the endocrine pancreas (relative level 22 vs. 7%).

128 noid contributions to the development of the endocrine pancreas remain unknown.

129 of the cardiovascular, immune, reproductive, endocrine pancreas, renal, and central nervous systems.

130 In the absence of menin, the endocrine pancreas showed increase in cell proliferation

131 s that play a role in the development of the endocrine pancreas, such as insulin promoter factor-1 an

132 recent advancements in research surrounding endocrine pancreas that hopefully will pave the way for

133 In this bioartificial endocrine pancreas, the hardware will be represented by

134 nitor, because of the inaccessibility of the endocrine pancreas, the integrated relationship with ins

135 Parasympathetic innervation of the endocrine pancreas, the islets of Langerhans, has been s

136 ction of insulin secreting beta-cells in the endocrine pancreas to prevent and/or delay the onset or

137 was to determine whether the response of the endocrine pancreas to this mild hypoglycemia can occur i

138 The endocrine pancreas undergoes major remodeling during neo

139 he structure and function of the neonatal CF endocrine pancreas using a new CFTR-knockout ferret mode

140 o investigate the role of GATA6 in the adult endocrine pancreas, we generated mice in which Gata6 is

141 ic pathways that regulate development of the endocrine pancreas, we generated transcriptional profile

142 two mouse models with Hhex deficiency in the endocrine pancreas, we show that Hhex is required for de

143 Nowhere is this more evident than in the endocrine pancreas, where disturbances in function or ma