ライフサイエンスコーパス: endocytic

1 We propose that PICK1 is a cargo-specific endocytic accessory protein required for efficient, acti

2 BAR domain, serving here as an example of an endocytic accessory protein.

3 us to mammalian podocytes, induced increased endocytic activity and accumulation of hemolymph protein

4 riactive zone and to maintain high levels of endocytic activity close to the synaptic ribbon.

5 son may be that neuronal membranes with high endocytic activity, including nerve terminals involved i

6 Flower mutant lacking binding sites for the endocytic adaptor AP-2 proteins fails to rescue endocyto

7 urons, and we show that PICK1 binding to the endocytic adaptor AP2 is enhanced by OGD in hippocampal,

8 riggers rapid down-regulation of CD4 via the endocytic adaptor protein 2 (AP-2) complex, a process li

9 Dab2) is a widely expressed clathrin binding endocytic adaptor protein and known for the endocytosis

10 ent study we explore the role of AP-2, a key endocytic adaptor protein complex, in the development of

11 During CME, endocytic adaptor proteins bind cargoes at the cell surf

12 Here, we have found that the endocytic adaptor proteins NUMB and NUMBL were required

13 ate ubiquitinated by CUL3-SPOPL as EPS15, an endocytic adaptor that also associates with the ESCRT-0

14 Gene-expression profiling identified the endocytic adaptor, Huntingtin-interacting protein 1-rela

15 Muniscins are a conserved family of endocytic adaptors, including Syp1 in budding yeast and

16 t PMEL is an excellent model system to study endocytic amyloid.

17 n in delivery and, therefore, degradation of endocytic and autophagic cargo in lysosomes.

18 These include the endocytic and autophagy pathways, which are characterize

19 The endocytic and cell signaling receptor, LDL receptor-rela

20 LDL receptor-related protein-1 (LRP1) is an endocytic and cell-signaling receptor.

21 of biotin-dependent trafficking through the endocytic and COPI systems.

22 ndria electrophile adduct excretion and cell endocytic and exocytic pathways.

23 Furthermore, endocytic and general trafficking genes are up-regulated

24 ered that the gene expression for regulating endocytic and lipid metabolic pathways was perturbed by

25 ols of newly deposited viral proteins within endocytic and nonendocytic compartments in VS target T c

26 target to compartments associated with both endocytic and phagocytic recycling functions, confirming

27 membrane deformation protein that links the endocytic and recycling machineries essential for dynami

28 e alphaS-associated vesicles were of diverse endocytic and secretory origin.

29 end-directed transport, which could modulate endocytic and secretory systems in intestinal cells.

30 receptor-related protein-1 (LRP1) is a large endocytic and signaling molecule broadly expressed by ne

31 ermining the complete lifespan of individual endocytic assemblies.

32 In addition to the localized endocytic assembly at the plasma membrane, intracellular

33 Endocytic, autophagic, and phagocytic vesicles move on m

34 at assembles into a helix around the neck of endocytic buds.

35 Therein, the endocytic C-type lectin receptors serve as pattern recog

36 anded apical endocytic pathway and increased endocytic capacity and lysosomal biogenesis.

37 Furthermore, endocytic capacity in fully differentiated cells is rapi

38 PT cells in culture up-regulate endocytic capacity in response to acute changes in fluid

39 tify Rab2 as a key factor for autophagic and endocytic cargo delivery to and degradation in lysosomes

40 ulate endosome maturation and trafficking of endocytic cargo to lysosomes in mammalian cells.

41 age 1 B cells show unimpaired degradation of endocytic cargo, have intact BCR signaling, and do not e

42 maturation of functional into nonfunctional/endocytic channels, rather than ZO-1 interfering with GJ

43 ce significant spatiotemporal alterations in endocytic clathrin coat dynamics.

44 Dynamics of endocytic clathrin-coated structures can be remarkably d

45 etention on the extracellular matrix and its endocytic clearance by the scavenger receptor low densit

46 Herein we investigated whether endocytic clearance of anti-ganglioside antibodies by ne

47 Stabilin receptors mediate the endocytic clearance of nanotubes.

48 cell integrin-binding site on fibrin or the endocytic collagen receptor, the mannose receptor.

49 ndocytosis just behind the hyphal apex (the "endocytic collar"); and small, rapidly moving puncta tha

50 normal macrophages, FPN1 cycles in the early endocytic compartment does not multimerize and is prompt

51 amatic relocalization and clustering of this endocytic compartment in the cell cortex.

52 We conclude that the terminal endocytic compartment is composed of acid-hydrolase-acti

53 Late endocytic compartments accumulate around Plasmodium berg

54 i In addition, BmHRG-1 localizes both to the endocytic compartments and cell membrane when expressed

55 cell-to-cell transfer intermediates as true endocytic compartments and resolve unique synapse-associ

56 ng roles in retrograde pathway(s) connecting endocytic compartments downstream of the post-Golgi endo

57 ssed in cultured astrocytes, ClC-4 sorted to endocytic compartments in WT cells but was retained in t

58 nsport internalized extracellular dsRNA from endocytic compartments into the cytoplasm for immune act

59 ed by single stranded RNA and DNA viruses in endocytic compartments resulting in endosomal hydrogen p

60 ion of mRNA uptake and release kinetics from endocytic compartments, the measurement of mRNA/protein

61 olae, and ADP-ribosylation factor-6+ (Arf6+) endocytic compartments.

62 and, depending on the APH1-variant, to late endocytic compartments.

63 vide evidence that PEN3 undergoes continuous endocytic cycling from the PM to the trans-Golgi network

64 A similar endocytic defect, however, was not observed in LRRK2 mut

65 In contrast, the endocytic-defective mutant was able to prevent sprout fo

66 This endocytic-defective mutant was unable to rescue the loss

67 barrier, we restored VE-Cad levels using an endocytic-defective VE-Cad mutant.

68 n, expression of a Y658F-VE-Cad mutant or an endocytic-defective Y658F-VE-Cad double mutant were both

69 Synapses of these mice displayed endocytic defects and a striking accumulation of clathri

70 awn mutants do, and they also do not display endocytic defects.

71 the host cell plasma membrane to hijack the endocytic-dependent membrane resealing machinery, thereb

72 icks internalise components of host blood by endocytic digest cells that line the tick midgut epithel

73 Endocytic down-regulation of cell-surface proteins is a

74 engthen evidence for a link between synaptic endocytic dysfunction and Parkinson's disease.

75 HERV-K ENV imparts an endocytic entry pathway that requires dynamin-mediated m

76 ion of Kv1.3 by inducing a clathrin-mediated endocytic event that targets the channel to lysosomal-de

77 Local endocytic events involving receptors for axon guidance c

78 e CME is difficult because the initiation of endocytic events is unpredictable.

79 of syt1 in single- as well as multi-vesicle endocytic events using high-resolution optical recording

80 onset of clathrin waves, but not individual endocytic events, requires feedback from downstream fact

81 a cathepsin inhibitor, indicating that it is endocytic F trafficking that is important for VLP assemb

82 Ubp7 has been characterized previously as an endocytic factor.

83 On soft substrates, most paxillin binds to endocytic factors and facilitates vesicle invagination,

84 ,5)P2, a reaction needed for the shedding of endocytic factors from their membranes.

85 he two proteins may be critical to regulated endocytic fission.

86 on activity, which was mediated by astrocyte endocytic function and adenosine receptors.

87 ofound interference with gene expression and endocytic function, likely further disrupting regulatory

88 suppressed by impairment and enhancement of endocytic function, respectively.

89 maintain the high-capacity ion transport and endocytic functions of this nephron segment.

90 d transmembrane protein 3 (IFITM3) restricts endocytic fusion of influenza virus.

91 Transferrin-coated endocytic gold nanorod cargoes initially undergo active

92 omplex as a key regulatory component in post-endocytic HPV trafficking.

93 nd the formation of vAC was compromised upon endocytic inhibition.

94 uncoating vesicles mature into Rab5-positive endocytic intermediates.

95 Our data argue against cytoskeletal or endocytic involvement and reveal a common role for Asap

96 ence elements on microR to regulate receptor endocytic lifetimes and the magnitude of arrestin-mediat

97 rotein signaling, suggesting that lengthened endocytic lifetimes were required for arrestin-biased si

98 ra and functionalizing the DNA shell with an endocytic ligand.

99 ersing post-Golgi compartments accessible to endocytic ligands before their arrival at the cell surfa

100 QDs for real-time imaging of three different endocytic ligands-folic acid, galectin-3 (Gal3) and the

101 tments, respectively, supporting an impaired endocytic lipid antigen presentation for T cell activati

102 eg) differentiation, the latter by promoting endocytic loss of IL-2 receptor-alpha (CD25).

103 model for Tulp1-mediated localization of the endocytic machinery at the periactive zone of ribbon syn

104 Assembly of the endocytic machinery is a constitutively active process t

105 Accordingly, functional endocytic machinery is essential for S2-mediated infecti

106 The diversion of the Cbl/CIN85 endocytic machinery may be a strategy utilized by the vi

107 of postsynaptic Homer1 and the Homer1-linked endocytic machinery necessary for maintaining normal cel

108 onstrate that Tda2 is a novel protein of the endocytic machinery necessary for normal internalization

109 haviruses infect host cells by utilizing the endocytic machinery of the cell and fusing their membran

110 g that Flower interacts with proteins of the endocytic machinery to mediate granule endocytosis.

111 LCa and CLCb, are integral components of the endocytic machinery whose differential functions remain

112 transport and a profound perturbation of the endocytic machinery, despite preserved absolute expressi

113 hoA activity and sequester paxillin from the endocytic machinery, thereby delaying neurite initiation

114 To further identify elements of the platelet endocytic machinery, we examined the role of a vesicle-r

115 ctivity and expression of genes encoding the endocytic machinery.

116 Moreover, there has been no distinction of endocytic-machinery components that are specific to acti

117 d cellular evidence that AP-2 interacts with endocytic markers SlaB(End4) and SagA(End3) and the lipi

118 of Dynamin and Rab5 activity, suggesting an endocytic mechanism.

119 How endophilin influences endocytic membrane fission is still unclear.

120 p2/3-mediated actin filament assembly drives endocytic membrane invagination and vesicle scission.

121 s not required for elongating or shaping the endocytic membrane invagination.

122 in understanding the roles of secretory and endocytic membrane trafficking pathways in plant immune

123 rsion to sphingosine-1-phosphate by SphK1 in endocytic membrane trafficking.

124 ed a role for sphingosine phosphorylation in endocytic membrane trafficking.

125 plasma membrane has long been implicated in endocytic membrane trafficking.

126 lecules, representing anionic amphiphiles of endocytic membranes.

127 stitutive internalization driven by a unique endocytic motif that also serves as a p120-catenin (p120

128 ndocytosis does not require the constitutive endocytic motif.

129 Here we identify the endocytic multidomain scaffold protein intersectin as an

130 the intrinsic membrane-sculpting activity of endocytic N-BAR domains.

131 tionarily, they unite not only secretory and endocytic organelles but also the flagellum and nucleus.

132 molecules are silent (off) inside the intact endocytic organelles, but can be turned on by redox acti

133 rowth, ClaH did not colocalize well with the endocytic patch marker fimbrin.

134 lli, inner ear stereocilia, immune synapses, endocytic patches, adhesion contacts, and invadosomes of

135 ed by the rate of ubiquitin flux through the endocytic pathway and by signaling pathways that converg

136 ytosolic domain of PAM-1 was produced in the endocytic pathway and entered the nucleus; very little s

137 er continuous FSS develop an expanded apical endocytic pathway and increased endocytic capacity and l

138 w describes our current understanding of the endocytic pathway and the multiligand receptors that med

139 lts uncover a novel function for DUBs in the endocytic pathway by which Ubp2 and Ubp15 positively reg

140 ppaB proinflammatory signaling from the late endocytic pathway compartments in autoantibody generatio

141 Our understanding of endocytic pathway dynamics is severely restricted by the

142 T cells use the endocytic pathway for key cell biological functions, inc

143 ecular mechanism of these alterations in the endocytic pathway in Parkin-deficient cells, we found th

144 ing proteins are important regulators of the endocytic pathway in yeast, facilitating selective ubiqu

145 These studies identified the LLO-dependent endocytic pathway of L. monocytogenes and support a nove

146 of LDL into endothelial cells via an unusual endocytic pathway that diverts the ligand from lysosomal

147 h a recently identified clathrin-independent endocytic pathway that requires the Rho1 GTPase.

148 Attenuation of the endocytic pathway through deletion of the gene END3 impa

149 asma membrane, and then recycles through the endocytic pathway to the Golgi for reuse in exocytosis.

150 ly, EphA2, to be a cargo of an RCP-regulated endocytic pathway which controls cell:cell repulsion and

151 d mitochondria occurs via an actin-dependent endocytic pathway which is consistent with macropinocyto

152 zation and cleavage, coupling entry into the endocytic pathway with proteolytic processing.

153 ired for Legionella's alteration of the host endocytic pathway, an activity required for this pathoge

154 ese results suggest that the activity of the endocytic pathway, which is known to be particularly imp

155 c analysis suggested an interaction with the endocytic pathway, which was confirmed by direct measure

156 s), which sends them into an Epsin-dependent endocytic pathway.

157 es are the major protein-sorting hubs of the endocytic pathway.

158 gnant mast cells by exploiting this Siglec-8 endocytic pathway.

159 cer cells through a folate receptor-mediated endocytic pathway.

160 utants lead to suppression through the yeast endocytic pathway.

161 es' disease, infects host cells by hijacking endocytic pathways and forming a Legionella-containing v

162 rity) of Rab GTPases along the secretory and endocytic pathways are established by their specific, co

163 data argue that prion strains use different endocytic pathways for infection and suggest that cell t

164 caco-2 cells demonstrated the involvement of endocytic pathways in cellular uptake.

165 Thus, the data presented here implicate endocytic pathways in HCMV maturation and egress.

166 es suggest that excessive ASYN likely alters endocytic pathways leading to axonal dysfunction in embr

167 Manipulation of canonical endocytic pathways only slightly influenced prion uptake

168 nt of HOS cells with inhibitors of different endocytic pathways suggest that uptake of EGFP-labelled

169 FYCO1 functionally connects autophagic and endocytic pathways, supporting the hypothesis that impai

170 on the details of PS-ASO trafficking through endocytic pathways.

171 s enter hair cells via both nonendocytic and endocytic pathways.

172 esence of inhibitors targeting components of endocytic pathways.

173 o-Phe (DPF) motifs within the early-arriving endocytic pioneers Eps15/R are differentially decoded by

174 Eps15/R are differentially decoded by other endocytic pioneers Fcho1/2 and AP-2.

175 embrane, we establish that without these two endocytic pioneers, AP-2 assemblies are fleeting and end

176 e that forms a helical collar at the neck of endocytic pits, and catalyzes membrane fission.

177 To follow dynamin GTP hydrolysis at endocytic pits, we generated a conformation-specific nan

178 ized actin provides mechanical force to form endocytic pits.

179 FPN1 cycles as a monomer within the endocytic/plasma membrane compartment and responds to it

180 Akt dependent, and is a clathrin-independent endocytic process, we determined whether THY-1 has a rol

181 through a selective, saturable subset of the endocytic process.

182 Endocytic processes are critical for cellular entry of s

183 uch as Rab5 and Rab7, both key regulators of endocytic processes.

184 ernalized SVLPs, which was dominated by slow endocytic processing via macropinocytosis, although some

185 her membrane-associated proteins and non-CME endocytic protein caveolin1 show no such curvature prefe

186 sue-specific ablation of dynamin-1 (cKO), an endocytic protein crucial for SV regeneration, enhances

187 trongly implicating Sac domain's activity in endocytic protein dynamics.

188 Using the endocytic protein epsin1 N-terminal homology domain (ENT

189 omplex, and surprisingly, associates with an endocytic protein, Rvs167p, suggesting a moonlighting fu

190 , NMDAR-dependent interactions with the core endocytic proteins AP2 and dynamin.

191 the emergence of the collective dynamics of endocytic proteins as periodic traveling waves on the ce

192 terminals where Tulp1 colocalizes with major endocytic proteins close to the synaptic ribbon.

193 demonstrate that Tulp1 is essential to keep endocytic proteins enriched at the periactive zone and t

194 membrane curvature affects the activities of endocytic proteins is much less explored, despite studie

195 Changes were observed in synaptic endocytic proteins when SMN-1 levels decreased.

196 endocytosis, and co-localizes strongly with endocytic proteins, including in ALS patient tissue.

197 Therefore, Lrp1 not only acts as an endocytic receptor but also directly participates in gen

198 The mannose receptor (MR) is an endocytic receptor involved in serum homeostasis and ant

199 crophages (TAMs) expressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contrib

200 In summary, we identify LAMP-2 as an endocytic receptor on human MoDC that routes cargo into

201 receptor-related protein 1 (LRP1) is a large endocytic receptor that binds and mediates the endocytos

202 ular protein and the largest known mammalian endocytic receptor.

203 in (LAMP) family includes the dendritic cell endocytic receptors DC-LAMP and CD68, as well as LAMP-1

204 These data demonstrate that endocytic receptors expressed on DCs contribute to the r

205 ein (Env gp140) to either CD40 or LOX-1, two endocytic receptors on dendritic cells (DCs), in rhesus

206 roliferation, decreased apical expression of endocytic receptors, and defective endocytosis.

207 Multiple studies have demonstrated DAT endocytic recycling and enhanced surface delivery in res

208 ndigested lysosomal material, which disrupts endocytic recycling and impairs their migration to, and

209 The plasma membrane and the endocytic recycling compartment (ERC) are both highly en

210 The endocytic recycling compartment (ERC) is a series of per

211 concentrated pool of MHC-I molecules in the endocytic recycling compartment (ERC).

212 he intracellular mechanisms that mediate DAT endocytic recycling following constitutive and regulated

213 ined action of two independent but redundant endocytic recycling mechanisms, together with distinct l

214 g (EHD) protein family play crucial roles in endocytic recycling of cell surface receptors from endos

215 its paralogs regulate multiple secretory and endocytic recycling pathways, yet the guanine nucleotide

216 Overall, our studies identify the endocytic recycling regulator EHD1 as a novel regulator

217 ies reveal a novel role of the EHD family of endocytic recycling regulatory proteins in TCR-mediated

218 Here we report that endocytic recycling requires active mechanistic target o

219 A-mediated Vps35 knockdown revealed that DAT endocytic recycling requires intact retromer.

220 o require dynamic phosphorylation events and endocytic recycling, although the molecular mechanisms t

221 dence for an in vivo function of syndapin in endocytic recycling, and suggest that syndapin promotes

222 ein family comprises 4 members that regulate endocytic recycling.

223 and that actin function contributes to PEN3 endocytic recycling.

224 gressively lost from the plasma membrane via endocytic recycling.

225 In contrast, depletion of either the endocytic regulator TRIP10 or the Rho GTPase activator V

226 most abundant KCC2 interactor is a neuronal endocytic regulatory protein termed PACSIN1 (SYNDAPIN1).

227 Our data suggest that rapid tuning of the endocytic response by changes in FSS may contribute to g

228 blation of snapin in mice recapitulates late endocytic retention of BACE1 and increased APP processin

229 rovides a powerful tool to further probe the endocytic route by which HERV-K infects cells.

230 hesised that prion strains rely on different endocytic routes to invade and replicate within their ta

231 3, through blocking its interaction with the endocytic scavenger receptor, low-density lipoprotein re

232 ptor ubiquitination state, suggesting a post-endocytic site of action.

233 a model in which NPFs form a ring around the endocytic site, centered by a spot of molecules attachin

234 During clathrin-mediated endocytosis (CME), endocytic-site maturation can be divided into two stages

235 work in vivo, giving actin assembly onset at endocytic sites a switch-like behavior.

236 The Tda2-Aim21 complex localizes to endocytic sites in a Bbc1- and filamentous actin-depende

237 early-arriving proteins select and stabilize endocytic sites is not known.

238 in, revealing barbed-end filament capping at endocytic sites to be a regulated event.

239 robe the mechanisms that concentrate NPFs at endocytic sites, and to investigate how NPFs regulate ac

240 1, one of the earliest proteins recruited to endocytic sites, facilitates site initiation and stabili

241 ape endocytic tubules and recruit dynamin to endocytic sites, it can also block membrane fission when

242 play central roles in concentrating NPFs at endocytic sites.

243 2, which engages different components of the endocytic sorting machinery during this process.

244 ur data indicate that the BBSome facilitates endocytic sorting of select membrane proteins at the bas

245 an cells undergoes constitutive endocytosis, endocytic sorting, and recycling, which delivers nutrien

246 consistent with the role of monoubiquitin in endocytic sorting.

247 central role for receptor ubiquitination in endocytic sorting.

248 orylated nephrin temporally colocalized with endocytic structures coincident with upregulation of Shc

249 of Notch receptors as they move through the endocytic system, we show that Numb specifically suppres

250 volved in the control of both autophagic and endocytic systems, has been studied extensively in numer

251 s caused cell-autonomous accumulation of the endocytic tracer atrial natriuretic factor-red fluoresce

252 In endocytic traffic, phosphatidylinositol-4,5-biphosphate

253 toplasmic Cl(-) level is required for proper endocytic trafficking and membrane supply during early s

254 on of ubiquitin conferred increased rates of endocytic trafficking and ubiquitin turnover.

255 rom CB1Rs and suggest modulation of receptor endocytic trafficking as a therapeutic approach to contr

256 EN1 (HOPM INTERACTOR7/BREFELDIN A-VISUALIZED ENDOCYTIC TRAFFICKING DEFECTIVE1) by coimmunoprecipitati

257 ation for previous, seemingly disparate, DAT endocytic trafficking findings.SIGNIFICANCE STATEMENT Th

258 ar basis of how these endosomal NHEs control endocytic trafficking is unclear.

259 ne domain or cytoplasmic tail that disrupted endocytic trafficking led to failure of F to function wi

260 Because endocytic trafficking of agonist-bound receptors is one

261 Time-dependent uptake and endocytic trafficking of Fg and dextran were followed us

262 The endocytic trafficking of PAM-1/OSX differed dramatically

263 s by providing the means to rapidly quantify endocytic trafficking of polyplexes and other vectors.

264 n this study, we demonstrate that the unique endocytic trafficking pathway of Hendra virus F protein

265 GIPC-mediated endocytic trafficking regulates PlexinD1 signaling.

266 However, post-endocytic trafficking required for virus capsid disassem

267 ultiple steps, from cell attachment, through endocytic trafficking towards the trans-Golgi network, a

268 surface availability is regulated acutely by endocytic trafficking, and considerable effort has been

269 identify Rab7A, a small GTPase important for endocytic trafficking, as a novel FLCN interacting prote

270 ction as a nexus between signaling and early endocytic trafficking.

271 pled receptors (GPCRs) has focused mainly on endocytic trafficking.

272 lectively activated in cancer cells to alter endocytic trafficking.

273 rovided that the F protein was competent for endocytic trafficking.

274 lished regulators of membrane fusion in late endocytic trafficking.

275 i complex and plays a poorly defined role in endocytic trafficking.

276 Signaling, in turn, modulates early endocytic trafficking.

277 ntly reduced by Vps34 deletion, resulting in endocytic/trafficking defects.

278 Here we analyze the endocytic transport function of the only C. elegans synd

279 psid uncoating, resulting in a defect in the endocytic transport of incoming PsVs.

280 Moreover, treatment of podocytes to inhibit endocytic transport or dynamin activity or remove cell s

281 s support our two-zone hypothesis to explain endocytic tubule elongation and vesicle scission in fiss

282 ns suggest that while endophilin helps shape endocytic tubules and recruit dynamin to endocytic sites

283 mode of cellular entry, a process involving endocytic uptake followed by endosomal escape and cytoso

284 transferrin receptor resulting in subsequent endocytic uptake of the payload.

285 tructural model for how acidification during endocytic uptake of the virus triggers the dissociation

286 us into SLAMF1-positive cells and identified endocytic uptake of viral particles.

287 lar energy levels, lysosomal biogenesis, and endocytic uptake, suggesting that these represent a coor

288 ever, whereas inversion of chirality reduces endocytic uptake, the d-peptide, once in the endosome, i

289 which the proteasome acquires a role in the endocytic-vacuolar pathway.

290 various endocytosis pathways and subsequent endocytic vesicle trafficking have been shown to strongl

291 Endocytic vesicle-mediated internalization of pre-formed

292 ong-standing question in cell biology is how endocytic vesicles and tubules detach from the plasma me

293 Endophilins A1 and A2 promote the budding of endocytic vesicles from the plasma membrane, whereas end

294 microscopy and subcellular fractionation of endocytic vesicles on a Percoll gradient.

295 required for recruitment of beta-arrestin to endocytic vesicles, which was dependent on co-expression

296 he transport of polyplexes through important endocytic vesicles.

297 major cargo protein of clathrin-independent endocytic vesicles.

298 ere subsequently taken up and accumulated in endocytic vesicles.

299 lysosomal metabolism of APP by altering its endocytic vesicular transport.

300 ctions are required for clustering AMPARs at endocytic zones in dendrites in response to NMDAR stimul