ライフサイエンスコーパス: endomesoderm

1 s reprogrammed and replaced the vegetal half endomesoderm.

2 and animal caps reprogrammed to replace all endomesoderm.

3 esoderm specification within the archenteron endomesoderm.

4 ways to distinguish neurogenic ectoderm from endomesoderm.

5 is sufficient to induce mesoderm in adjacent endomesoderm.

6 sion have been observed in the pre-gastrular endomesoderm.

7 al to specification of the sea urchin embryo endomesoderm.

8 e planar cell divisions between ectoderm and endomesoderm.

9 o establish asymmetric MAPK signaling in the endomesoderm.

10 time is crucial to the specification of the endomesoderm.

11 and/or maintenance of this region as dorsal endomesoderm.

12 ed protein that is expressed in the anterior endomesoderm.

13 berus are early marker genes of the anterior endomesoderm (AE), a subset of endoderm cells fated to f

14 rdm1/Blimp1 was proposed to promote anterior endomesoderm and head development in Xenopus laevis.

15 t contributes to the repression of spec2a in endomesoderm and oral ectoderm territories.

16 pression in different spatial domains of the endomesoderm, and at different times.

17 in of the mesoderm, as both ectomesoderm and endomesoderm, appears to be a condition present in all s

18 ula whereas others required the induction of endomesoderm, as indicated by their inhibition by Cerber

19 expression is reduced by a morpholino, more endomesoderm cells become pigment and other mesenchymal

20 lateral cells, develop from a single pair of endomesoderm cells, the A6.3 blastomeres, which form par

21 lements of the provisional GRN for embryonic endomesoderm development in the sea urchin are here comp

22 ox gene, itself expressed zygotically in the endomesoderm during cleavage; and by a Tcf1/beta-catenin

23 the non-skeletogenic mesoderm (NSM) from the endomesoderm during sea urchin embryo development.

24 induce both the division orientation of the endomesoderm (EMS) blastomere and the endoderm fate of t

25 In this study, we show that the vegetal endomesoderm expresses lvnumb during the blastula and ga

26 The later endomesoderm expression of foxN2/3 is independent of the

27 us, consistent with its role in endoderm and endomesoderm formation in anthozoan cnidarians, ascidian

28 to assess roles of annotated phosphatases in endomesoderm formation, a literature review of phosphata

29 r, previously shown to be enriched in embryo endomesoderm fractions, are the predominant, if not excl

30 ic bilaterians evolved from the bifunctional endomesoderm (gastrodermis) of a diploblastic ancestor,

31 r model of the Strongylocentrotus purpuratus endomesoderm gene network.

32 Recent work on the sea urchin endomesoderm gene regulatory network (GRN) offers many o

33 al node of the well-characterized sea urchin endomesoderm gene regulatory network (GRN).

34 genes in the vegetal hemisphere, called the endomesoderm gene regulatory network (GRN).

35 the endoderm specification subcircuit of the endomesoderm gene regulatory network in the Strongylocen

36 ar beta-catenin/TCF-Lef, which activates the endomesoderm gene regulatory network, and SoxB1, which a

37 chyury and FoxA transcription factors in the endomesoderm gene regulatory network.

38 otch at least, display similar capacities in endomesoderm gene regulatory networks.

39 It has been held that endomesoderm generates the majority of adult mesodermal

40 To gain further insight into control of endomesoderm GRN activation, we have identified a sea ur

41 In the sea urchin, an endomesoderm GRN model explains much of the specificatio

42 s the placement and function of Pmar1 in the endomesoderm GRN model.

43 ing specific subcircuits from the sea urchin endomesoderm GRN, for which both circuit design and biol

44 Within the hierarchy of the endomesoderm GRN, these subcircuits are organized in an

45 pecific predictions of the sea urchin embryo endomesoderm GRN.

46 st steps in the initiation of the sea urchin endomesoderm GRN.

47 mic regulatory code, at this key node of the endomesoderm GRN.

48 just as predicted for the delta gene in the endomesoderm GRN.

49 ference those governing specification of the endomesoderm in sea urchin embryos and dorsal-ventral pa

50 This gene is expressed in the endomesoderm in the blastula and later the gut of the em

51 mesectoderm in the Drosophila embryo and the endomesoderm in the sea urchin, even though the respecti

52 e uncharacterised early signal (ES) inducing endomesoderm in the sea urchin, suggesting that ES may b

53 Endomesoderm, including the complex assemblage of circul

54 cromere progeny, and expression of the early endomesoderm induction signal necessary for full specifi

55 that Pmar1 controls expression of the early endomesoderm induction signal.

56 The segregation of embryonic endomesoderm into separate endoderm and mesoderm fates i

57 the sea urchin embryo, specification of the endomesoderm is accomplished by the activity of a networ

58 ne: it represses mesodermal fate in the veg2 endomesoderm; it is required in postgastrular developmen

59 in the specification events that define the endomesoderm; later it functions as a gut-specific diffe

60 ted factor that is expressed in the anterior endomesoderm of gastrula stage embryos and can induce th

61 work (GRN) controls the process by which the endomesoderm of the sea urchin embryo is specified.

62 Notch signaling initiates segregation of the endomesoderm precursor field by inhibiting expression of

63 central to the maternal specification of the endomesoderm prior to gastrulation.

64 on in all cell types, although expression in endomesoderm progenitors is enhanced.

65 with Tcf to antagonize the expression of key endomesoderm regulatory genes.

66 d blimp1/krox inputs into other genes of the endomesoderm regulatory network.

67 ressed in the visceral endoderm and anterior endomesoderm, respectively, and the prechordal plate of

68 Significantly, therefore, in sea stars, endomesoderm segregation arises through transcriptional

69 Thus, we report that endomesoderm segregation is a progressive process, requi

70 We also argue that ectomesoderm and endomesoderm should not be considered as the exclusive p

71 The proximal element bound to SpGATA-E, an endomesoderm-specific transcription factor.

72 ribed roles for the wnt signaling pathway in endomesoderm specification during gastrulation and overa

73 an intercellular signaling loop which drives endomesoderm specification forward early in sea urchin e

74 ied morpholinos to either hox11/13b or foxA (endomesoderm specification genes), the isolated animal c

75 ility of combinatorial control mechanisms in endomesoderm specification in Caenorhabditis.

76 for a specific role for BMP signaling during endomesoderm specification in the early branching metazo

77 n the gene regulatory network that underlies endomesoderm specification in the embryo.

78 ode in the gene regulatory network (GRN) for endomesoderm specification in the sea urchin embryo lies

79 This network is a subelement of the overall endomesoderm specification network of the Strongylocentr

80 shed gene regulatory network (GRN) model for endomesoderm specification places pmar1 early in the mic

81 r the early phase of gatae expression during endomesoderm specification.

82 his form is required for the early events of endomesoderm specification.

83 h play a central role in both early and late endomesoderm specification.

84 e nuclei of vegetal blastomeres and controls endomesoderm specification.

85 -catenin at one pole of the embryo initiates endomesoderm specification.

86 18 other genes expressed specifically during endomesoderm specification.

87 nsive experimental evidence now available on endomesoderm specification.

88 ity and number of genes than are involved in endomesoderm specification.

89 of marker genes expressed zygotically during endomesoderm specification.

90 hat of vertebrate receptors, are enriched in endomesoderm, suggesting that the SpFGFR variants could

91 red on the neuroectoderm by signals from the endomesoderm that are largely inseparable from those of

92 We model the endomesoderm tissue specification process in the vegetal

93 second and third quartets of micromeres, and endomesoderm, which is formed from the fourth quartet mi