ライフサイエンスコーパス: endomorphin-1

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1 dia and attenuated the hypotensive effect of endomorphin 1.

2 ed the bradycardia and hypotension caused by endomorphin 1.

3 The endogenous opioid peptide endomorphin-1 (1) was modified by attachment of lactose

4 Endomorphin 1 (10, 30, 100 nmol/kg) administered intrave

5 (POMC), the precursor to beta-endorphin, and endomorphin 1 and 2 on sectioned rat forebrain revealed

6 Endomorphin 1 and 2 were below the detection limit of th

7 Endomorphin-1 and -2 (EM1, EM2) are endogenous opioids w

8 We suggested that the endomorphins (endomorphin-1 and -2) might be biased toward arrestin re

9 Therefore, because the potencies of endomorphin-1 and endomorphin-2 to elicit internalizatio

10 tment, whereas a few agonists, in particular endomorphins 1 and 2, display apparent bias toward arres

11 vation induced by the endogenous MOR agonist endomorphin-1, and a cross-antagonism, by which a MOR an

12 in the rat VTA induced by local infusion of endomorphin-1, demonstrating a key role of MOR-Gal1R het

13 inuous exposure of the cloned mu receptor to endomorphin-1 did not diminish the subsequent ability of

14 g-Phe, and the putatively endogenous peptide endomorphin-1 displayed particularly distinct bias profi

15 g the 60 min of observation, indicating that endomorphin-1 does not induce rapid desensitization of t

16 affinity mu opioid receptor (MOR) agonists, endomorphin-1 (E-1) and -2 (E-2), modulate ASIC currents

17 Light microscopic studies have shown that endomorphin-1 (EM-1) -containing fibers are distributed

18 tracerebroventricular (i.c.v.) injections of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) in the rat

19 morphine and the endogenous opioid peptides, endomorphin-1 (EM-1) and endomorphin-2 (EM-2), on mu opi

20 Endomorphin-1 (EM-1) is a recently isolated endogenous p

21 endogenous mu-opioid receptor (MOR) agonists endomorphin 1 (EM1) and 2 (EM2) were tested for their ca

22 n, the endogenous kappa receptor agonist) or endomorphin 1 (EM1, the endogenous mu receptor agonist)

23 The present study examined the effect of endomorphin-1 (EM1), an endogenous opioid with a high af

24 Endomorphin-1 (EM1), in contrast to several other mu opi

25 A series of diastereoisomers of endomorphin-1 (EM1, Tyr(1)-Pro(2)-Trp(3)-Phe(4)-NH(2)) h

26 Bilateral administration of endomorphin-1 in the globus pallidus of rats induced oro

27 u-opioid receptors, the behavioral effect of endomorphin-1 in the globus pallidus was blocked by the

28 have investigated the behavioral effects of endomorphin-1 in the globus pallidus, a brain region tha

29 Infusion of endomorphin-1 internalized MOR.

30 Gly-N-Met-Phe-glycinol-enkephalin (DAMGO) or endomorphin-1, into the medial preoptic nucleus attenuat

31 riene E4, Lysopc(20:4), 5-methoxytryptamine, Endomorphin-1, Lysopc(20:3)) were good prediction for th

32 provides no support for the hypothesis that endomorphin-1 modulates the consolidation of conditioned

33 hat the highly selective mu receptor agonist endomorphin-1 modulates the expression of conditioned de

34 The distributions of endomorphin 1 (Tyr-Pro-Trp-Phe-NH2; EM1) and endomorphin

35 Endomorphin-1 (Tyr-Pro-Trp-Phe-NH(2); EM1) and endomorph

36 and isolation from brain of such a peptide, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), which has a high af

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