ライフサイエンスコーパス: endoplasmic reticulum membrane

1 vement of misfolded polypeptides through the endoplasmic reticulum membrane.

2 Sec61 translocon prior to insertion into the endoplasmic reticulum membrane.

3 xpansion, without proliferating the cortical endoplasmic reticulum membrane.

4 s that are organized in a complex within the endoplasmic reticulum membrane.

5 sufficient information for targeting to the endoplasmic reticulum membrane.

6 es synthesizing presecretory proteins to the endoplasmic reticulum membrane.

7 ghly enriched in the mitochondria-associated endoplasmic reticulum membrane.

8 the potential to affect interactions at the endoplasmic reticulum membrane.

9 quence of KvAP S4 can be inserted across the endoplasmic reticulum membrane.

10 omplex during their translocation across the endoplasmic reticulum membrane.

11 chaperones and enzymes on both sides of the endoplasmic reticulum membrane.

12 roper protein folding and/or assembly in the endoplasmic reticulum membrane.

13 e boundary between a bud and the surrounding endoplasmic reticulum membrane.

14 talytic sites relative to the surface of the endoplasmic reticulum membrane.

15 binding and peptide translocation across the endoplasmic reticulum membrane.

16 ing the translocation and integration at the endoplasmic reticulum membrane.

17 predicted to be on the cytosolic side of the endoplasmic reticulum membrane.

18 equired for peptide translocation across the endoplasmic reticulum membrane.

19 its (Ost3p and Stt3p) in a subcomplex in the endoplasmic reticulum membrane.

20 f the nascent lipoprotein particles from the endoplasmic reticulum membrane.

21 -translational insertion through or into the endoplasmic reticulum membrane.

22 ufficient to prevent ribosome binding to the endoplasmic reticulum membrane.

23 in targeting to and translocation across the endoplasmic reticulum membrane.

24 of single type 1 InsP(3)R channels in native endoplasmic reticulum membrane.

25 easomes following their dislocation from the endoplasmic reticulum membrane.

26 te targeting to and translocation across the endoplasmic reticulum membrane.

27 anslational protein translocation across the endoplasmic reticulum membrane.

28 before precursor protein transfer across the endoplasmic reticulum membrane.

29 ytoplasm, where some are associated with the endoplasmic reticulum membrane.

30 in the translocation of proteins across the endoplasmic reticulum membrane.

31 cretory proteins are translocated across the endoplasmic reticulum membrane.

32 wo alternate transmembrane structures at the endoplasmic reticulum membrane.

33 tionally to the Sec61 complex present in the endoplasmic reticulum membrane.

34 probably exists on the cytosolic face of the endoplasmic reticulum membrane.

35 component of the VKOR enzyme complex in the endoplasmic reticulum membrane.

36 f the protein translocation apparatus of the endoplasmic reticulum membrane.

37 osome-nascent chain complex, the SRP and the endoplasmic reticulum membrane.

38 e E1 proteins most likely takes place in the endoplasmic reticulum membrane.

39 the adaptor protein STING on the surface of endoplasmic reticulum membrane.

40 main are segregated on opposite sides of the endoplasmic reticulum membrane.

41 eins to the Sec61 protein translocase in the endoplasmic reticulum membrane.

42 is and Asp residues on opposite sides of the endoplasmic reticulum membrane.

43 n nuclear deformation and a proliferation of endoplasmic reticulum membrane.

44 al cytoplasmic membrane or to the eukaryotic endoplasmic reticulum membrane.

45 tial lipid transporter that localizes to the endoplasmic reticulum membrane.

46 ting a phase transition in the lipids of the endoplasmic reticulum membrane.

47 protein, transfer it, and insert it into the endoplasmic reticulum membrane.

48 endoplasmic reticulum or is retained in the endoplasmic reticulum membrane.

49 cognition particle-dependent transfer to the endoplasmic reticulum membrane.

50 y interacts with the hydrophobic core of the endoplasmic reticulum membrane.

51 characterized by solving its topology in the endoplasmic reticulum membrane.

52 phosphatase complex localized in the nuclear/endoplasmic reticulum membrane.

53 ptor (IP(3)R) Ca(2+) release channels in the endoplasmic reticulum membrane.

54 membrane-domain-docking site embedded in the endoplasmic-reticulum membrane.

55 cytochrome P450 reductase (CPR) in mammalian endoplasmic reticulum membranes.

56 a membrane fraction with characteristics of endoplasmic reticulum membranes.

57 ouse MCs and is localized to the nuclear and endoplasmic reticulum membranes.

58 trol of the permeability of mitochondria and endoplasmic reticulum membranes.

59 proteins on cisternal and protein body rough endoplasmic reticulum membranes.

60 mmunication between events in the plasma and endoplasmic reticulum membranes.

61 tar is located in the nuclear and contiguous endoplasmic reticulum membranes.

62 hin cells, possibly by binding components in endoplasmic reticulum membranes.

63 o the outer mitochondrial, outer nuclear and endoplasmic reticulum membranes.

64 g in vitro insertion of fusion proteins into endoplasmic reticulum membranes.

65 the cell cycle progression and the fusion of endoplasmic reticulum membranes.

66 hreshold previously found for PFO binding to endoplasmic reticulum membranes.

67 rather attaches the protein peripherally to endoplasmic reticulum membranes.

68 d, 26 S proteasome-mediated degradation from endoplasmic reticulum membranes, a reaction that slows a

69 ding proteins (SREBPs) are released from the endoplasmic reticulum membrane, allowing them to translo

70 ls are low, the SREBPs are released from the endoplasmic reticulum membrane, allowing them to translo

71 proteins with the translocon complex of the endoplasmic reticulum membrane and are cleaved off durin

72 secretory vesicles, Golgi, mitochondria, and endoplasmic reticulum membrane and associates with the m

73 ining genes by tethering Opi1 to the nuclear/endoplasmic reticulum membrane and controlling its trans

74 PM8), which is localized in the keratinocyte endoplasmic reticulum membrane and controls mitochondria

75 of integral membrane proteins located in the endoplasmic reticulum membrane and includes the gamma-ca

76 TCC-1 localizes to the endoplasmic reticulum membrane and interacts with UNC-11

77 nt-shaped membranes were continuous with the endoplasmic reticulum membrane and oriented with the con

78 ures Ca2+ release from discrete sites in the endoplasmic reticulum membrane and random spatial distri

79 importin-alpha-16 after integration into the endoplasmic reticulum membrane and release from the tran

80 ocation of class I MHC heavy chains from the endoplasmic reticulum membrane and target them for prote

81 uggest that Nrf1 is normally targeted to the endoplasmic reticulum membrane and that endoplasmic reti

82 Close contacts between the endoplasmic reticulum membrane and the mitochondrial out

83 antibodies that faithfully recognized rough endoplasmic reticulum membranes and amyloid fibrils, the

84 s localized to fractions that contained both endoplasmic reticulum membranes and BiP.

85 Like MP:GFP, TAD5:GFP interacted with the endoplasmic reticulum membranes and colocalized with its

86 signal recognition particle was bound to the endoplasmic reticulum membranes and less was in the free

87 lular localizations, with rsec22 residing on endoplasmic reticulum membranes and rbet1 found on Golgi

88 Once activated, Sar1/GTP binds to endoplasmic reticulum membranes and recruits COPII coat

89 polypeptide being synthesized, binds to the endoplasmic reticulum membrane, and even nonsecretory pr

90 ptides, transport of the peptides across the endoplasmic reticulum membrane, and expression of the MH

91 ane-bound ribosomes, translocated across the endoplasmic reticulum membrane, and GPI-anchored by GPI

92 ane phospholipids, the growth of the nuclear/endoplasmic reticulum membrane, and the formation of lip

93 al domain not shared by M87, may insert into endoplasmic reticulum membrane, and together with reticu

94 n to cause extensive remodeling of Golgi and endoplasmic reticulum membranes, and a number of the hos

95 stribution from cytosol to mitochondrial and endoplasmic reticulum membranes, and caspase-independent

96 1a accumulation, localization to perinuclear endoplasmic reticulum membranes, and recruitment of 2a(p

97 le Bcl-2 is located in the mitochondrial and endoplasmic reticulum membranes as well as the nuclear e

98 opose that this NPL4 function extends to all endoplasmic reticulum-membrane-associated targets of the

99 ngle-domain b5 and b5R proteins localized on endoplasmic reticulum membrane, b5+b5R also has binding

100 is thought to contact the lipid core of the endoplasmic reticulum membrane based on antibody epitope

101 pro-alpha-factor (ppalphaF) across the yeast endoplasmic reticulum membrane begins with the binding o

102 very high levels in developing endosperm in endoplasmic reticulum membrane-bound protein bodies.

103 o target the proteasome to the ubiquitinated endoplasmic reticulum membrane-bound proteins Mga2p and

104 In fission yeast, the endoplasmic reticulum membrane-bound proteins Sre1 and S

105 ol regulatory element binding protein, is an endoplasmic reticulum membrane-bound transcription facto

106 o synthesize N-glycan precursors) across the endoplasmic reticulum membrane, but subsequent studies s

107 , are inserted post-translationally into the endoplasmic reticulum membrane by a dedicated protein-ta

108 Cytochromes P450 (P450) are anchored to the endoplasmic reticulum membrane by an N-terminal transmem

109 Cytochrome P450 is anchored to the endoplasmic reticulum membrane by an N-terminal transmem

110 complex that directs ribosomes to the rough endoplasmic reticulum membrane by binding to targeting s

111 ne-bound protein that was removable from the endoplasmic reticulum membrane by chaotropic salt wash,

112 repeat (TPR) domain that is anchored to the endoplasmic reticulum membrane by Sec71.

113 us, are post-translationally targeted to the endoplasmic reticulum membrane by the guided entry of TA

114 -binding proteins (SREBPs) are released from endoplasmic reticulum membranes by proteases whose activ

115 terminal domains of SREBPs are released from endoplasmic reticulum membranes by two sequential cleava

116 quence showed that this protein resembles an endoplasmic reticulum membrane Ca(2+)-ATPase.

117 ol 1,4,5-trisphosphate (IP(3)) receptors are endoplasmic reticulum membrane calcium channels that, up

118 Protein transport across the endoplasmic reticulum membrane can occur by two pathways

119 Although particle assembly takes place on endoplasmic reticulum membranes, capsid localizes in nuc

120 -dependent carboxylase, a constituent of the endoplasmic reticulum membrane, catalyzes the conversion

121 how an identical switch-like specificity for endoplasmic reticulum membrane cholesterol.

122 cells and in cells depleted for adaptin-3 or endoplasmic reticulum membrane complex subunits, also id

123 ge PM clusters that represent specialized PM:endoplasmic reticulum membrane contact sites (PM:ER MCS)

124 The top gene sets included severe CP ("endoplasmic reticulum membrane," "cytochrome P450," "mic

125 Association of apoA-V with endoplasmic reticulum membrane defects promotes nascent

126 this fusion protein gives rise to a type of endoplasmic reticulum membrane domain in which adjacent

127 ting Gaa1 and associated GPIT subunits to an endoplasmic reticulum membrane domain.

128 receptor (InsP(3)R) targeting to specialized endoplasmic reticulum membrane domains are unknown.

129 The recruitment of endoplasmic reticulum membrane during phagosome biogenes

130 is the core structural component of a large endoplasmic reticulum membrane-embedded protein complex

131 lin-induced gene 1 (Insig-1) and Insig-2 are endoplasmic reticulum membrane-embedded sterol sensors t

132 the NE in both these circumstances involves endoplasmic reticulum membranes enveloping the chromatin

133 n the outer mitochondrial membrane (OMM) and endoplasmic reticulum membrane (ERM) of living human fib

134 es, such as temperature sensitivity, nuclear/endoplasmic reticulum membrane expansion, decreased tria

135 sensitivity, respiratory deficiency, nuclear/endoplasmic reticulum membrane expansion, derepression o

136 h1Delta mutant did not result in the nuclear/endoplasmic reticulum membrane expansion, which occurs i

137 the N-terminal segment anchors RoDH1 to the endoplasmic reticulum membrane facing the cytosol.

138 equired for protein translocation across the endoplasmic reticulum membrane following translation.

139 lved in the transport of peptides across the endoplasmic reticulum membrane for antigen presentation,

140 transporters, transports peptides across the endoplasmic reticulum membrane for assembly of major his

141 rokaryotic plasma membrane or the eukaryotic endoplasmic reticulum membrane for secretion or membrane

142 The Sec61 translocon of the endoplasmic reticulum membrane forms an aqueous pore tha

143 suppression of SREBP activation, we isolated endoplasmic reticulum membrane fractions from long-term

144 Lipidomic analyses reveal that endoplasmic reticulum membranes from Plin2-null mice are

145 se Atlastin has recently been shown to drive endoplasmic reticulum membrane fusion and three-way junc

146 The structure of this enzyme of the endoplasmic reticulum membrane has remained unknown for

147 release of leader peptide remnants from the endoplasmic reticulum membrane, hence its name.

148 AP translocates cellular peptides across the endoplasmic reticulum membrane in an ATP hydrolysis-depe

149 ssociation with the cytosolic surface of the endoplasmic reticulum membrane in cells.

150 eceptor to the protein-conducting channel on endoplasmic reticulum membrane in eukaryotes or plasma m

151 ss the plasma membrane in prokaryotes or the endoplasmic reticulum membrane in eukaryotes.

152 We assessed N tail translocation across the endoplasmic reticulum membrane in the presence and absen

153 s in VKOR can individually insert across the endoplasmic reticulum membrane in vitro.

154 This orientation of ACAT2 in the endoplasmic reticulum membrane, in addition to its expre

155 labeling at the cytosolic side of the rough endoplasmic reticulum membranes, in the nucleus, occasio

156 er immobilization through association to the endoplasmic reticulum membrane, initial proximity betwee

157 t chain complexes to the SRP receptor in the endoplasmic reticulum membrane, initiating translocation

158 ral domains from the late proteins supported endoplasmic reticulum membrane insertion as transmembran

159 f cholera toxin retrotranslocates across the endoplasmic reticulum membrane into the cytosol, where i

160 ional targeting of secretory proteins to the endoplasmic reticulum membrane involves the recognition

161 tween ribosomes and the pore proteins at the endoplasmic reticulum membrane is important to co-transl

162 protein in that its translocation across the endoplasmic reticulum membrane is inefficient, resulting

163 Anchoring of this protein segment to the endoplasmic reticulum membrane is likely to bring the me

164 However, whilst STIM1 in the endoplasmic reticulum membrane is the critical sensor fo

165 Ralpha, suggesting that dislocation from the endoplasmic reticulum membrane is the rate-limiting step

166 The topography of the PS molecule in the endoplasmic reticulum membrane is widely accepted as exh

167 The homotypic fusion of endoplasmic reticulum membranes is catalyzed by the atla

168 ed that ECA1p was associated mainly with the endoplasmic reticulum membranes isolated from Arabidopsi

169 ATPase SERCA2b transports Ca(2+) across the endoplasmic reticulum membrane maintaining a vital Ca(2+

170 nel 2 (VDAC2) at the mitochondria-associated endoplasmic reticulum membrane (MAM) prior to its transl

171 ses fluorescently tagged nuclear envelope or endoplasmic reticulum membrane marker proteins to precis

172 ated in the plant cytoplasm, associated with endoplasmic reticulum membranes; medicarpin biosynthetic

173 thylmaleimide (NEM)-sensitive isoform in the endoplasmic reticulum membrane (microsomal GPAT) and an

174 ah1Delta effects on lipid synthesis, nuclear/endoplasmic reticulum membrane morphology, and lipid dro

175 ns is prevented by chaperones present in the endoplasmic reticulum membrane; now the first experiment

176 on of SRP-dependent targeting of RNCs to the endoplasmic reticulum membrane observed with long nascen

177 Translocation of p42 into the endoplasmic reticulum membrane occurs cotranslationally

178 -helical membrane proteins directly into the endoplasmic reticulum membrane of eukaryotes or into the

179 anslational protein translocation across the endoplasmic reticulum membrane of yeast requires a seven

180 IP(3)) receptors form tetrameric channels in endoplasmic reticulum membranes of mammalian cells and m

181 osophila RyR and GFP-Drosophila RyR-C on the endoplasmic reticulum membranes of transfected cells.

182 provide essential lipid modifications in the endoplasmic reticulum membrane or function as molecular

183 complete translocation across the eukaryotic endoplasmic reticulum membrane or the prokaryotic plasma

184 d fatty acids at concentrations that lead to endoplasmic reticulum membrane phospholipid remodeling i

185 osphatidate to produce diacylglycerol at the endoplasmic reticulum membrane, plays a major role in co

186 elix of GTP-bound Sar1 stably penetrates the endoplasmic reticulum membrane, promoting local membrane

187 Because p97 is known to bind to the endoplasmic reticulum membrane protein AMFR (gp78), an E

188 oorly characterized secreted protein, EMC10 (endoplasmic reticulum membrane protein complex subunit 1

189 own as seipin) is a lipodystrophy-associated endoplasmic reticulum membrane protein essential for whi

190 The endoplasmic reticulum membrane protein Rft1 is intimatel

191 processing is Ste24p/Afc1p, a multispanning endoplasmic reticulum membrane protein that contains an

192 Lec35 mutant phenotype and predicts a novel endoplasmic reticulum membrane protein.

193 tter step is mediated by Ste14p, an integral endoplasmic reticulum membrane protein.

194 avage-activating protein (SCAP), a polytopic endoplasmic reticulum membrane protein.

195 These results establish Sel K as an endoplasmic reticulum-membrane protein important for pro

196 ween co-translational and post-translational endoplasmic-reticulum membrane protein targeting and ins

197 nding of the membrane domain of reductase to endoplasmic reticulum membrane proteins called Insig-1 a

198 Recent work on several endoplasmic reticulum membrane proteins has shown that t

199 he founding member of a homologous family of endoplasmic reticulum membrane proteins present in all e

200 In Saccharomyces cerevisiae the endoplasmic reticulum membrane proteins scSpt23p and scM

201 (IP(3)Rs) are large, ubiquitously expressed, endoplasmic reticulum membrane proteins that form tetram

202 Insig-2 is one of two endoplasmic reticulum membrane proteins that inhibit cho

203 Insig-1 and Insig-2, closely related endoplasmic reticulum membrane proteins, mediate transcr

204 inal proteolytic fragments of two homologous endoplasmic reticulum membrane proteins, Spt23p and Mga2

205 r enrichment of endogenous mitochondrial and endoplasmic reticulum membrane proteins.

206 proteasome gene or accumulation of misfolded endoplasmic reticulum membrane proteins.

207 1a accumulates on endoplasmic reticulum membranes, recruits 2a(pol), and i

208 ping and helicase-like domains, localizes to endoplasmic reticulum membranes, recruits BMV 2a polymer

209 otypes, such as the expansion of the nuclear/endoplasmic reticulum membrane, reduced lipid droplet fo

210 onsible, with the major pool of STIM1 in the endoplasmic reticulum membrane regulating CRAC channel a

211 Cav-1(S80E) targets to the endoplasmic reticulum membrane, remains oligomeric, and

212 It is proposed that formation of VKOR in the endoplasmic reticulum membrane resembles formation of th

213 -dependent gamma-carboxylation system in the endoplasmic reticulum membrane responsible for gamma-car

214 unexpected link between perturbation of the endoplasmic reticulum membrane's lipid phase, induction

215 doplasmic reticulum, and sitosterol-enriched endoplasmic reticulum membranes show evidence of membran

216 x that dephosphorylates Pah1p at the nuclear/endoplasmic reticulum membrane, stabilized Pah1p abundan

217 Accumulation of sterols in endoplasmic reticulum membranes stimulates the ubiquitin

218 Although YBR159W localizes to the endoplasmic reticulum membrane, subcellular fractionatio

219 sion through the continuous nuclear envelope/endoplasmic reticulum membrane system.

220 controls an aspect of MPD orientation in the endoplasmic reticulum membrane that is crucial for its a

221 fied a region integrally associated with the endoplasmic reticulum membrane that is likely to interac

222 ors form tetrameric, IP(3)-gated channels in endoplasmic reticulum membranes that govern the release

223 ght protein translocation defects across the endoplasmic reticulum membrane, the principal role of th

224 At the endoplasmic reticulum membrane, the prion protein (PrP)

225 ain interactions in translocation across the endoplasmic reticulum membrane, the translocation of wil

226 al integration of a nascent protein into the endoplasmic reticulum membrane, the transmembrane (TM) s

227 rotein substrates are transported across the endoplasmic reticulum membrane through a translocation c

228 eins is established cotranslationally at the endoplasmic reticulum membrane through the action of alt

229 ts are properly targeted and oriented in the endoplasmic reticulum membrane, thus making them amenabl

230 olic enzyme that associates with the nuclear/endoplasmic reticulum membrane to catalyze the dephospho

231 des in the cytoplasm and translocates to the endoplasmic reticulum membrane to catalyze the phosphati

232 ulum where they retro-translocate across the endoplasmic reticulum membrane to enter the cytoplasm.

233 CP)/p97 extracts misfolded subunits from the endoplasmic reticulum membrane to the cytosolic proteaso

234 the vehicles of protein transport across the endoplasmic reticulum membrane), transmembrane segments,

235 RNF170 is an endoplasmic reticulum membrane ubiquitin ligase that con

236 cytosolic organelles that protrude from the endoplasmic reticulum membrane under energy-rich conditi

237 ide, a fraction of GRP94 associated with the endoplasmic reticulum membrane undergoes specific proteo

238 rminants that direct protein topology at the endoplasmic reticulum membrane usually function with hig

239 and is anchored to the cytosolic face of the endoplasmic reticulum membrane via a hydrophobic C-termi

240 ions containing the D13 scaffold protein and endoplasmic reticulum membranes were also present.

241 This protein is localized to the endoplasmic reticulum membrane where it performs the met

242 ls emphasize the role of STIM located in the endoplasmic reticulum membrane, where a Ca2+-binding EF-

243 for activity on the cytoplasmic side of the endoplasmic reticulum membrane, whereas the analogous se

244 , and His-176 reside on the same side of the endoplasmic reticulum membrane, which is supported by th

245 The recent discovery of fusion of endoplasmic reticulum membrane with nascent phagosomes s

246 es with the coating of specific areas of the endoplasmic reticulum membrane with Sar1-GTP and the Sec

247 We show that maMYB is associated with the endoplasmic reticulum membrane with the transcription fa

248 ytes resulted in an interspersion of nuclear/endoplasmic reticulum membranes with the chromatin.