ライフサイエンスコーパス: endorphin

1 ltered cleavage profile for the peptide beta-endorphin.

2 a-neoendorphin, but not endomorphins or beta-endorphin.

3 cyte-stimulating hormone (beta-MSH) and beta-endorphin.

4 ulating hormone, and the opioid peptide beta-endorphin.

5 beta-lipotropin to gamma-lipotropin and beta-endorphin.

6 in the level of C-terminally processed beta-endorphin.

7 sed for dual immunocytochemistry of Fos/beta-endorphin.

8 gh the post-translational processing of beta-endorphin.

9 MC), or PVN levels of Met-Enkephalin or beta-Endorphin.

10 beta-lipotropic hormone (beta LPH), and beta endorphin.

11 de Y, vasoactive intestinal peptide, or beta-endorphin.

12 acid decarboxylase 67 (GAD67), NPY, and beta-endorphin.

13 duced increases in nitrite, nitrate and beta-endorphin.

14 ate an NO-dependent neuronal release of beta-endorphin.

15 abolites nitrite and nitrate as well as beta-endorphin.

16 for their content of NO metabolites and beta-endorphin.

17 a against the endogenous opioid peptide beta-endorphin.

18 or lacking either pre-pro-enkephalin or beta-endorphin.

19 as methadone and endogenous opioids such as endorphins.

20 imulating hormone, beta-lipotrophin, and the endorphins.

21 s well as to endogenous peptide ligands like endorphins.

22 bital-anesthetized rats pretreated with beta-endorphin (0.5 nmol i.c.v.).

23 tidase which converts beta-endorphin to beta-endorphin 1-17 (gamma-endorphin), beta-endorphin 1-18, a

24 beta-endorphin 1-17 (gamma-endorphin), beta-endorphin 1-18, and their corresponding C-terminal fragm

25 ministration of morphine (1 microg) and beta-endorphin (1 microg) into either the amygdala alone or t

26 Co-administration of beta-endorphin (1 microg) into the amygdala and morphine (1 m

27 rphine (1 microg) into the amygdala and beta-endorphin (1 microg) into the PAG failed to produce inte

28 milar effects of intra-DVC injection of beta-endorphin (1 pmol) are inhibited by naloxone and not by

29 n (epsilon)-opioid-receptor antagonist, beta-endorphin(1-27) prevents these effects of etorphine.

30 one (LAAM), morphine, meperidine, DADL, beta-endorphin(1-31), enkephalins, and dynorphin A(1-17) prod

31 o the suppressive actions of Gly-Gln or beta-endorphin-(1-27) injections that modulate voluntary etha

32 y was shown to be comparable to central beta-endorphin-(1-27) or intraperitoneal (i.p.) naltrexone-in

33 ontrast, the opioid peptidergic agonist beta-endorphin (10 microgram/kg, i.p.) administered after the

34 Following intrathecal administration, beta-endorphin (10-100 nmol) and GRP (1-10 nmol) dose-depende

35 is of fluorogenic peptides based on the beta-endorphin 12-24 sequence, Abz-T-P-L-V-T-L-X(1)-X(2)-N-A-

36 he rostral ventromedial medulla altered beta-endorphin (15 microg) analgesia elicited from the ventro

37 Both morphine (2.5-5 micrograms) and beta-endorphin (2.5-5 micrograms) microinjected into either t

38 Glycyl-L-glutamine (Gly-Gln; beta-endorphin 30-31) is an endogenous dipeptide that is synt

39 investigated whether glycyl-glutamine (beta-endorphin(30-31)), an inhibitory dipeptide synthesized f

40 ffective in reducing morphine (60%) and beta-endorphin (79%) analgesia in the amygdala on the jump te

41 pro-opiomelanocortin, the precursor of beta-endorphin (a known EOP), and constituted the majority of

42 the DVC, whereas the similar effects of beta-endorphin, a peptide derived from the same precursor, ar

43 ted by, in part, the endogenous opioid, beta-endorphin, acting on mu-opioid receptors.

44 y opioids, leading to the proposal that beta-endorphin acts to provide feedback inhibition.

45 piratory depression produced by central beta-endorphin administration.

46 We found that beta-endorphin aggregation and dissociation occur in vitro on

47 arbohydrates exhibit the same effect on beta-endorphin aggregation as phosphate.

48 t as well as more rapid dissociation of beta-endorphin amyloid fibrils at lower pH indicate the contr

49 In contrast, beta-endorphin amyloid fibrils obtained in the presence of he

50 tors on the assembly and disassembly of beta-endorphin amyloids in vitro.

51 exercise increases blood levels of both beta-endorphin (an opioid) and anandamide (an endocannabinoid

52 wever, the A118G variant receptor binds beta-endorphin, an endogenous opioid that activates the mu op

53 significantly reduce both morphine and beta-endorphin analgesia elicited from the amygdala.

54 for the full expression of morphine and beta-endorphin analgesia elicited from the amygdala.

55 significantly reduced morphine, but not beta-endorphin analgesia in the amygdala on the tail-flick te

56 ultiple modulatory mechanisms mediating beta-endorphin analgesia in the PAG, and in terms of whether

57 The opioid mediation of beta-endorphin analgesia in the ventrolateral periaqueductal

58 Whereas mecamylamine failed to reduce beta-endorphin analgesia on either measure, scopolamine produ

59 %) and transient (30 min) reductions in beta-endorphin analgesia on the jump test, MK-801 produced mi

60 %) and transient (30 min) reductions in beta-endorphin analgesia on the tail-flick test.

61 %) and transient (30 min) reductions in beta-endorphin analgesia on the tail-flick test.

62 es with mice confirm that these glycosylated endorphin analogues are potential drug candidates that p

63 A series of glycosylated endorphin analogues designed to penetrate the blood-brai

64 Glycosylated beta-endorphin analogues of various amphipathicity were studi

65 es in the helical address region of the beta-endorphin analogues without destroying mu-, delta-, or k

66 gy states are suggested for the glycosylated endorphin analogues, a flexible aqueous state and a rest

67 owed colocalization of cathepsin L with beta-endorphin and alpha-MSH in the intermediate pituitary an

68 tion, mediated by the hedonic action of beta-endorphin and anhedonic effects of withdrawal, may theor

69 e neurons produce the endogenous opioid beta-endorphin and are heavily regulated by opioids.

70 As the opioid peptides beta-endorphin and enkephalin increase splenic NK cell functi

71 measurement of instrumental behavior of beta-endorphin and enkephalin knock-out mice that both opioid

72 We conclude that both beta-endorphin and enkephalin positively contribute to the in

73 nules yet expresses endogenous opioids (beta-endorphin and Met-enkephalin) and uroguanylin in apical

74 In addition, we have shown that beta-endorphin and mu-opiate receptor are expressed at the pr

75 The expression of both beta-endorphin and mu-opiate receptor correlated positively w

76 try and immunoelectron microscopy using beta-endorphin and mu-opiate receptor specific antibodies.

77 e brain-to-blood transport of morphine, beta-endorphin and other opioids.

78 ) neurons release the endogenous opioid beta-endorphin and POMC neuron activity is inhibited by opioi

79 infiltration of immunocytes containing beta-endorphin and the consequent decrease of the beta-endorp

80 uctural differences between melittin or beta-endorphin and their respective synthetic analogs.

81 ver, neurons triple-labeled with c-Fos, beta-endorphin and VGLUT3 were noted in this region following

82 However, endorphins and dopamine have a much wider compass than o

83 pletely prevented carboxy-shortening of beta-endorphins and greatly diminished conversion of beta-lip

84 n MRM transitions for alpha-endorphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorphin were m/z 873.6

85 euroendocrine peptides (dynorphin A-17, beta-endorphin, and alpha- melanocyte-stimulating hormone) in

86 nes adrenocorticotropic hormone (ACTH), beta-endorphin, and alpha-melanocyte stimulating hormone (alp

87 cathepsin L in the production of ACTH, beta-endorphin, and alpha-MSH peptide hormones in the regulat

88 ut mice showed major decreases in ACTH, beta-endorphin, and alpha-MSH that were reduced to 23, 18, an

89 alpha-, beta-, and gamma-melanotropin, beta-endorphin, and beta-lipotropin.

90 ropin-releasing hormone (GnRH), VP, OT, beta-endorphin, and dopamine neurons, are responsive to mu-re

91 iomelanocortin (POMC), the precursor to beta-endorphin, and endomorphin 1 and 2 on sectioned rat fore

92 ioid receptor agonists (e.g., morphine, beta-endorphin, and enkephalin) inhibit luteinizing hormone (

93 dotropin-releasing hormone-I, dopamine, beta-endorphin, and gonadotropin-releasing hormone-II neurons

94 gesic responses induced by morphine and beta-endorphin, and indicate that the latter response is medi

95 actin, corticotropin-releasing hormone, beta-endorphin, and somatotropin release-inhibiting factor.

96 as well as its derivatives beta LPH and beta-endorphin, and that this process is modulated by TPA, IL

97 lications for theories of the involvement of endorphins, and as a causal factor.

98 ived feeding states but were reduced in beta-endorphin- and enkephalin-deficient mice only when they

99 nmol) dose-dependently attenuates both beta-endorphin- and GRP-elicited robust scratching without af

100 The same pathway produces beta-endorphin, another POMC derivative, which potentially co

101 ted for three different receptors: anti-beta-endorphin anti-body, streptavidin, and thrombin, and the

102 n, growth hormone releasing factor, and beta-endorphin are nearly equivalent substrates for the enzym

103 Enkephalins and beta-endorphin are nonselective endogenous MOR ligands.

104 POMC), and its opioid cleavage product, beta-endorphin, are expressed in the mouse retina.

105 ng a monoclonal antibody (3E-7) against beta-endorphin as a target, we selected a single peptide with

106 ntial affinity to the endogenous ligand beta-endorphin as well as alterations in pain sensitivity, dr

107 Wild type IDE cleaved beta-endorphin at Leu(17)-Phe(18) and Phe(18)-Lys(19), wherea

108 Nardilysin cleaves beta-endorphin at the monobasic site, Phe(17)-Lys(18), with a

109 in pain modulation-metenkephalin (ME), beta-endorphin (BE), and substance P (SP)-in patients undergo

110 Within 36 h after TPA stimulation, beta-endorphin became undetectable in cell extracts, coincidi

111 To enhance beta-endorphin (BEP), the endogenous opioid polypeptide that

112 ic NSCs differentiated these cells into beta-endorphin (BEP)-producing neurons in culture.

113 The endogenous peptides beta-endorphin (beta-END) and neuropeptide Y (NPY) have been

114 leasing hormone (CRH), urocortin (Ucn), beta-endorphin (beta-END), ACTH, and corticosterone (CORT) or

115 also exists for the endogenous opiate, beta-endorphin (beta-END).

116 The enzymatic cleavage products of beta-endorphin (beta-endorphin1-27 and Gly-Gln) reduce volunt

117 The role of beta-endorphin (beta-EP) in ethanol-altered NK cell cytolytic

118 The mechanism by which ethanol induces beta-endorphin (beta-EP) neuronal death during the developmen

119 system is involved in ethanol-regulated beta-endorphin (beta-EP) release from rat hypothalamic neuron

120 beta-endorphin to beta-endorphin 1-17 (gamma-endorphin), beta-endorphin 1-18, and their corresponding

121 ced by the mu-sensitive opioid peptide, beta-endorphin (betaEND, 10 microg, i.c.v.) was significantly

122 CB1R activation selectively increases beta-endorphin but not alpha-melanocyte-stimulating hormone r

123 Thus, beta-endorphin cell therapy may offer some therapeutic value

124 A recognized beta-endorphin cleavage product, Gly-Gln, inhibits voluntary

125 of cell bodies containing enkephalin or beta-endorphin, colchicine (90-100 microg/kg) was injected in

126 G) may have higher receptor binding for beta-endorphin compared with AA homozygotes that may contribu

127 of oxidation products of NO as well as beta-endorphin, compared to levels in fractions collected und

128 in arterial pressure elicited by i.c.v. beta-endorphin, consistent with evidence that cyclic dipeptid

129 The results suggest that although beta-endorphin-containing fibres are absent in many parts of

130 y, CB(2) immunolabeling was detected on beta-endorphin-containing keratinocytes in stratum granulosum

131 phin and the consequent decrease of the beta-endorphin content in the inflamed tissue.

132 peritoneally twice at 3 h intervals, and the endorphin content of microdialysates was analyzed by a s

133 though conversion of beta-lipotropin to beta-endorphin decreased, the lack of PC2 activity caused an

134 Adult male beta-endorphin deficient and wild type mice were subjected to

135 Overall, the beta-endorphin deficient mice and wild type mice had fairly s

136 After the conflict, the beta-endorphin deficient mice had higher corticosterone level

137 e aggressive conspecific several of the beta-endorphin deficient mice showed clear signs of counter a

138 In this experiment beta-endorphin deficient mice were used to study the role of

139 turned to baseline levels faster in the beta-endorphin deficient mice.

140 In this study, we used the beta-endorphin deficient mutant mouse line C57BL/6-Pomc1(tm1L

141 in proenkephalin knockout (PENK KO) and beta-endorphin-deficient (BEND KO) mice, and how the body wei

142 Herein we demonstrate that morphine and beta-endorphin disrupt this long-range synchrony of gamma osc

143 activity and the stimulated release of beta-endorphin during exposure of rats to N(2)O.

144 u and kappa opioid receptors as well as beta-endorphin each produce analgesia elicited from the amygd

145 ies have demonstrated that morphine and beta-endorphin employ different anatomical and neurochemical

146 at's hindpaw elicits an accumulation of beta-endorphin-(END) containing immune cells.

147 d neurons double-labeled with c-Fos and beta-endorphin, enkephalin or VGLUT3 in the ARC were signific

148 er, growth hormone releasing factor and beta-endorphin exhibit a 40-fold higher kcat, but a 10-fold d

149 nic mice with a selective deficiency of beta-endorphin exhibit normal analgesia in response to morphi

150 UVB stimulated beta-endorphin expression was higher in D2 than in B6.

151 beta-endorphin), heterozygous mice (50% beta-endorphin expression) and sibling wildtype mice from the

152 eptor activation induces the release of beta-endorphin from keratinocytes and the activation of G-pro

153 nt POMC cDNA produced a mutant beta-MSH/beta-endorphin fusion protein.

154 sor-to-product ion MRM transitions for alpha-endorphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorph

155 h the rank order of etorphine > DAMGO = beta-endorphin > morphine > butorphanol, and the affinity of

156 beta-Endorphin had an LOD of 5 nM when detected directly, but

157 Functional studies showed that beta-endorphin has potent melanogenic, mitogenic, and dendrit

158 ting hormone; and the endogenous opioid beta-endorphin) have a diverse array of biological activities

159 ozygous knockout mice (entirely lacking beta-endorphin), heterozygous mice (50% beta-endorphin expres

160 hemorrhage increased Fos expression by beta-endorphin immunoreactive neurons significantly.

161 The proportion of beta-endorphin immunoreactive neurons that expressed Fos immu

162 beta-endorphin immunostaining, whereas beta-endorphin-immunoreactive neurons were absent in retinas

163 xtracts, coinciding with an increase of beta-endorphin-immunoreactive protein in the culture medium.

164 significant increases in POMC mRNA and beta-endorphin immunoreactivity in both ipsilateral and contr

165 ressing amacrine cells was positive for beta-endorphin immunostaining, whereas beta-endorphin-immunor

166 h nerve fibers containing enkephalin or beta-endorphin in both the rVLM and vlPAG.

167 A physiological role for beta-endorphin in endogenous pain inhibition was investigated

168 ed secretion of both chromogranin A and beta-endorphin in response to the usual secretagogue, cortico

169 /or dendrites) containing enkephalin or beta-endorphin in specific regions of the brain stem.

170 nalgesia elicited by either morphine or beta-endorphin in the amygdala could be altered by either the

171 omelanocortin (POMC) neurons to release beta-endorphin in the arcuate nucleus (ARC) of the hypothalam

172 A, orexin B, and a novel isoform of rat beta-endorphin in the arcuate nucleus.

173 hat enhancement of endogenous levels of beta-endorphin in the hypothalamus via beta-endorphin neuron

174 on of AAS also increased the content of beta-endorphin in the midline thalamus, suggesting a possible

175 but decreased the potency of the opioid beta-endorphin in the periaqueductal gray region of the midbr

176 20 cells resulted in increased ACTH and beta-endorphin in the regulated secretory pathway.

177 adiation, to date a functional role for beta-endorphin in the regulation of human epidermal melanocyt

178 lanocyte-stimulating hormone (MSH), and beta-endorphin in the regulation of skin pigmentation, and a

179 he data do not support a major role for beta-endorphin in the regulation of sleep or social stress-in

180 ivates neurons containing enkephalin or beta-endorphin in the rVLM as well as in the periaqueductal g

181 rphin were used to study the release of beta-endorphin in the urethane anaesthetized rat following el

182 nal structures containing enkephalin or beta-endorphin in these regions.

183 ation of epidermal ACTH, alpha-MSH, and beta-endorphin in vitiligo owing to oxidation of methionine r

184 , leu-enkephalin, dynorphin A(1-8), and beta-endorphin in vivo.

185 Quantification of alpha- and gamma-endorphins in rat brain using liquid chromatography-elec

186 ndogenous concentrations of alpha- and gamma-endorphins in rat brains were 13.8+/-0.57 (mean+/-SD; n=

187 eficient mice were used to study the role of endorphins in the acute physiological and behavioral res

188 transiently elevated extracellular levels of endorphins in the nucleus accumbens, whereas nicotine an

189 mission of endogenous opioid peptides (i.e., endorphins) in the nucleus accumbens.

190 Beta endorphin-induced constriction was enhanced following FP

191 produced a dose-dependent inhibition of beta-endorphin-induced hypotension, but not bradycardia, with

192 beta-endorphin inhibition of tumor progression also involves

193 ctive toward the physiological peptides beta-endorphin, insulin, and amyloid beta peptide 1-40.

194 administration of subthreshold doses of beta-endorphin into both structures also results in a profoun

195 doses of morphine into both structures, beta-endorphin into both structures, morphine into one struct

196 to the other structure, or morphine and beta-endorphin into one structure.

197 of morphine, mu-selective agonists and beta-endorphin into the amygdala.

198 ctures, morphine into one structure and beta-endorphin into the other structure, or morphine and beta

199 Beta-endorphin is an endogenous opioid peptide that is releas

200 beta-Endorphin is an opioid peptide cleaved from the precurso

201 Furthermore, beta-endorphin is approximately three times more potent at th

202 The cancer-preventive effect of beta-endorphin is mediated through the suppression of sympath

203 l stimulus was applied, suggesting that beta-endorphin is necessary for CB(2) receptor-mediated antin

204 Whereas plasma beta-endorphin is reported to increase after exposure to ultr

205 important mechanism of the transport of beta-endorphin is the cerebrospinal fluid.

206 [D-Ala(2)]-gamma-endorphin is used as an internal standard.

207 rodents, another POMC-derived peptide, beta-endorphin, is coordinately synthesized in skin, elevatin

208 e and behavioral effects were absent in beta-endorphin knockout mice and in mice lacking p53-mediated

209 An antibody that selectively recognized beta-endorphin labeled fibers and neurons in the ventral horn

210 used an increase in beta-lipotropin and beta-endorphin levels in the mutant animals, but no increases

211 beta-endorphin levels increased in the inflamed paw, and this

212 on, and plasma interleukin-1 (IL-1) and beta-endorphin levels measured.

213 reatening episodes implicates increased beta-endorphin levels resulting from acid-mediated esophageal

214 Resting plasma beta-endorphin levels were significantly higher in the HPT <4

215 en, dyadic satisfaction correlated with beta-endorphin levels, depression, and perception of illness.

216 dic satisfaction scores correlated with beta-endorphin levels.

217 Moreover, we show that oxidized beta-endorphin loses its function in the promotion of pigment

218 ypothesize that this drug-induced release of endorphins may contribute to the positive reinforcing an

219 A popular belief has been that endogenous endorphins mediate these beneficial effects.

220 itary chemosensory cells that coexpress beta-endorphin, Met-enkephalin, uroguanylin, and Trpm5 exist

221 In conclusion, the results suggest that beta-endorphin modulates the acute endocrine, thermoregulator

222 These data support the hypothesis that beta-endorphin modulates the response to EtOH.

223 sal links for itch-eliciting effects by beta-endorphin-MOP receptor and GRP-BB2 receptor systems and

224 roM concentrations of etorphine, DAMGO, beta-endorphin, morphine, and butorphanol, DAMGO-stimulated G

225 igned to examine the involvement of the beta-endorphin/mu-opiate receptor system in human epidermal m

226 cortin-1 receptor, we conclude that the beta-endorphin/mu-opiate receptor system participates in the

227 melanocytes express a fully functioning beta-endorphin/mu-opiate receptor system.

228 beta-endorphin in the hypothalamus via beta-endorphin neuron transplantation suppresses stress respo

229 2.6%, depending on neuronal location), beta-endorphin neurons (68.3.0 +/- 4.4%), and VP neurons (41-

230 hyperpolarize guinea pig hypothalamic (beta-endorphin) neurons.

231 to traditional mu and kappa opioids and beta-endorphin, none of the OFQ/N fragments in the amygdala e

232 beta LPH and beta-endorphin of keratinocyte origin may thus be involved in

233 epinephrine and norepinephrine but not beta-endorphin or cortisol.

234 dynorphin1-13 but not antisera against beta-endorphin or methionine-enkephalin.

235 ardiorespiratory depression produced by beta-endorphin or morphine.

236 D can improve the sequence coverage for beta-endorphin over performing ECD alone (i.e., from 72 to 97

237 orks) to show that three neuropeptides (beta-endorphin, oxytocin, and dopamine) play particularly imp

238 Glycopeptides related to beta-endorphin penetrate the blood-brain barrier (BBB) of mic

239 N) (P<0.05), but did not have lower PVN beta-endorphin peptide levels (0.05).

240 and synthetic agonists including endogenous endorphin peptides, morphine and methadone.

241 The opioid peptide beta-endorphin plays a critical role in bringing the stress a

242 n inhibitory dipeptide synthesized from beta-endorphin post-translationally, inhibits IL-1beta and PG

243 V8 expressing the analgesic gene prepro-beta-endorphin (ppbetaEP) led to significant (P < 0.0001) rev

244 for insulin-degrading enzyme as both a beta-endorphin-processing and -inactivating enzyme is implica

245 experiments tested the hypothesis that beta-endorphin-producing neurons, that is, proopiomelanocorti

246 c acid (GABA), neuropeptide Y (NPY), or beta-endorphin receptor blockade in the ipsilateral hypothala

247 ascular reflexes through enkephalin- or beta-endorphin-related opioid receptors in the rostral ventro

248 ature, at least in part, by stimulating beta-endorphin release from pro-opiomelanocortin neurons that

249 AM1241 stimulated beta-endorphin release from rat skin tissue and from cultured

250 The time-integrated beta-endorphin response to CRH was greater in the patients wi

251 Depolarization-mediated beta-endorphin secretion was greatly enhanced in the GAP-43-e

252 , sensation, plasma levels of cortisol, beta-endorphin, selected gut neuropeptides, norepinephrine, e

253 keratinocytes, subsequently increasing beta-endorphin signaling at opioid receptors, and produces an

254 During this period, beta-endorphin stimulates PRL secretion by regulation of dopa

255 (tail-flick: 70-75%; jump: 60-81%) and beta-endorphin (tail-flick: 100%; jump: 93%) analgesia elicit

256 lpha-melanocyte-stimulating hormone and beta-endorphin, the glucocorticoids; and the catecholamines n

257 hormone (alpha-Msh) and carboxy-cleaved beta-endorphin, the products of Cpe-dependent processing of P

258 shown the distribution of dynorphin and beta-endorphin throughout social behavior circuits within the

259 ine contains a peptidase which converts beta-endorphin to beta-endorphin 1-17 (gamma-endorphin), beta

260 attachment, binding of the neuropeptide beta-endorphin to mu-opioid receptors in the central nervous

261 ne regulating feeding behavior, whereas beta-endorphin underlies orosensory reward in high need state

262 geting mu-receptors, such as enkephalins and endorphins, underlying the regulation of feeding and bod

263 A functional role for beta-endorphin was assessed in epidermal melanocyte cultures

264 125I-beta-Endorphin was cross-linked to preparations enriched in p

265 Little immunoreactive-beta-endorphin was detected in the areas of brain sampled dur

266 Basal secretion of beta-endorphin was first observed at Embryonic Day 13.5 (e13.

267 d in rats when naloxone or antiserum to beta-endorphin was injected in the hindpaw where the noxious

268 Hindpaw injection of beta-endorphin was sufficient to produce antinociception.

269 mity to fibers containing enkephalin or beta-endorphin, was observed in the rVLM and ventrolateral PA

270 ate an NO-dependent neuronal release of beta-endorphin, we conducted a ventricular-cisternal perfusio

271 en the powerful analgesic properties of beta-endorphin, we tested this hypothesis using pain toleranc

272 tern blot analysis, POMC, beta LPH, and beta-endorphin were detected in cell extracts under baseline

273 PAG, while no cell bodies labeled with beta-endorphin were identified in either region.

274 rphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorphin were m/z 873.6-->429.6; 929.6-->542.3; 936.6--

275 Met-Enkephalin and beta-Endorphin were not affected by dietary treatment.

276 d antibodies to the carboxy-terminus of beta-endorphin were used to study the release of beta-endorph

277 chanism allows for the local release of beta-endorphin, where CB(2) receptors are present, leading to

278 y to inflamed sites, where they release beta-endorphin which activates peripheral opioid receptors to

279 timulates release from keratinocytes of beta-endorphin, which acts at local neuronal mu-opioid recept

280 and exercise both induce the release of beta-endorphin, which plays an important role in the modulati

281 Unlike beta-endorphin, which produces itch and attenuates inflammato

282 keratinocytes of the endogenous opioid beta-endorphin, which then acts at opioid receptors on primar

283 There was no correlation of IL-1 or beta-endorphin with any psychosocial or behavioral compliance

284 copy studies revealed an association of beta-endorphin with melanosomes.