ライフサイエンスコーパス: endospore

1 nter) and Clostridia (forming heat-resistant endospores).

2 nthracis persists as a metabolically dormant endospore.

3 nvironment, B. anthracis exists as a dormant endospore.

4 composed of two layers, the exospore and the endospore.

5 e wall protein (SWP3) that is located in the endospore.

6 le as a metabolically dormant cell type, the endospore.

7 samples that contained only several hundred endospores.

8 the spore photoproduct (SP), in germinating endospores.

9 gs containing multiple cysts (sporangia) and endospores.

10 pring of Epulopiscium-like bacteria are true endospores.

11 sibility that the phase-bright offspring are endospores.

12 rotein was immunolocalized to the surface of endospores.

13 ical of the parental strain and did not form endospores.

14 responsible for the strong UV resistance of endospores.

15 y to produce progeny in the form of multiple endospores.

16 produce live offspring instead of quiescent endospores.

17 n the genomic DNA of UV-irradiated bacterial endospores.

18 clusive DNA photodamage product in bacterial endospores.

19 that are capable of producing heat-resistant endospores.

20 clusive DNA photodamage product in bacterial endospores.

21 to accumulate in the surface regions of the endospores.

22 ents of the protective surface layers of the endospores.

23 problem of real-time detection of bacterial endospores.

24 ogether, the two pathways allow B. anthracis endospores a broader recognition of purines and amino ac

25 ted of juxtaposed immature spherules without endospores, a germinating endospore, or thick-walled hyp

26 ThT and (ii) the accumulation of ThT in the endospores, affording fluorescence images with excellent

27 oluble components of the cell, including the endospore and cytoplasm, and in ligand blots binds to pu

28 morphological similarity between developing endospores and Epulopiscium offspring, we hypothesized t

29 ped for detection of Bacillus anthracis (BA) endospores and for differentiation of them from other sp

30 mer, spore photoproduct (SP), in germinating endospores and is responsible for the strong UV resistan

31 lostridia classes, are their ability to form endospores and their "Gram-positive" single-membraned, t

32 database of Raman spectra of single Bacillus endospores and to calculate classification functions, wh

33 ation of a small sample of Bacillus subtilis endospores (approximately 10(4) spores).

34 In addition, endospores are formed as part of the normal daily life c

35 We show that multiple endospores are generated both by asymmetric division at

36 Bacterial endospores are some of the most resilient forms of life

37 ture and structural variability of bacterial endospores as a function of spatial and developmental or

38 sms was investigated using Bacillus subtilis endospores as model microbial agents and simulated and n

39 All members of the Bacillus genus produce endospores as part of their life cycle; however, it is n

40 of the cell and by symmetric division of the endospores at an early stage of their development.

41 the Veillonellaceae) of Clostridia that form endospores but that are surprisingly "Gram negative," po

42 We also failed to detect the presence of endospores by light microscopy or by testing for heat-re

43 Bacterial endospores can remain dormant for decades yet can respon

44 dospores is surrounded by the densely packed endospore coat and exosporium, containing amyloid or amy

45 t, it is the impenetrable composition of the endospore coat and the exosporium that makes staining me

46 acid (DPA) is a major component of bacterial endospores, comprising 5-15% of the spore dry weight, an

47 The bacterial endospore cortex peptidoglycan is synthesized between th

48 Bacterial endospores derive much of their longevity and resistance

49 UV resistance of bacterial endospores derives from a unique DNA photochemistry in w

50 porium that makes staining methodologies for endospore detection complex and challenging.

51 ect the forespore and the mother cell during endospore development in the bacterium Bacillus subtilis

52 At an early stage during Bacillus subtilis endospore development the bacterium divides asymmetrical

53 A metalloproteinase (Mep1) secreted during endospore differentiation digests an immunodominant cell

54 Bacterial endospore dormancy and resistance properties depend on t

55 ination, implicating gerS in the breaking of endospore dormancy in vivo.

56 gen (SOWgp) and prevents host recognition of endospores during the phase of development when these fu

57 we also found that B. anthracis bacilli and endospores exhibited arginase activity, possibly competi

58 olyspora relies on the formation of multiple endospores for reproduction.

59 al to all clostridia is the orchestration of endospore formation (i.e., sporulation) and, specificall

60 Endospore formation (sporulation) is a well conserved mi

61 Endospore formation (sporulation), extensively studied i

62 The broad distribution of endospore formation among the Epulopiscium phylogenetic

63 hich are expressed in the mother cell during endospore formation and which are essential for the acti

64 At an early stage in endospore formation Bacillus subtilis partitions itself

65 Studies of endospore formation by Bacillus subtilis and fruiting bo

66 Endospore formation by Bacillus subtilis involves three

67 Endospore formation by Bacillus subtilis is a complex an

68 up III IMMP that regulates Bacillus subtilis endospore formation by cleaving Pro-sigma(K) and releasi

69 Endospore formation in amino-acid-rich medium was signif

70 During endospore formation in Bacillus subtilis an asymmetric d

71 n and DNA packaging, that are common to both endospore formation in Bacillus subtilis and the product

72 Endospore formation in Bacillus subtilis begins with an

73 Endospore formation in Bacillus subtilis is primarily de

74 Recent studies on endospore formation in Bacillus subtilis suggest that an

75 At the onset of endospore formation in Bacillus subtilis the DNA-binding

76 During endospore formation in Bacillus subtilis, over two dozen

77 During endospore formation in Bacillus subtilis, over two dozen

78 During endospore formation in Bacillus subtilis, several integr

79 At the onset of endospore formation in Bacillus subtilis, the DNA bindin

80 During endospore formation in Bacillus subtilis, the DNA bindin

81 nscription factor controls the initiation of endospore formation in Clostridium acetobutylicum, but g

82 (iii) The molecular apparatus of endospore formation in Clostridium serves as raw materia

83 The bacterium Bacillus subtilis undergoes endospore formation in response to starvation.

84 ot all, highly conserved genes diagnostic of endospore formation in the genomes of low G+C Gram-posit

85 Endospore formation is coordinated with transit of the b

86 A key step in bacterial endospore formation is engulfment, during which one bact

87 A hallmark of bacterial endospore formation is engulfment, during which the memb

88 eed to conserve biosynthetic capacity during endospore formation might have favored the evolution of

89 (chemotaxis, competence for DNA uptake, and endospore formation) by analyzing their phylogenetic dis

90 During Bacillus subtilis endospore formation, a complex protein coat is assembled

91 teria to reduced and stringent selection for endospore formation, as well as to novel environmental c

92 licum, in contrast to the model organism for endospore formation, Bacillus subtilis, and confirm that

93 How solvent production is coupled to endospore formation--both stationary-phase events--remai

94 ween the appearance of clostridial forms and endospore formation.

95 ring production in Epulopiscium evolved from endospore formation.

96 f several genes required during the onset of endospore formation.

97 ression of CTS1 is markedly increased during endospore formation.

98 f spoIIG and other promoters at the onset of endospore formation.

99 complex developmental program culminating in endospore formation.

100 on efficiency and a delay in the kinetics of endospore formation.

101 duction in Epulopiscium shares features with endospore formation.

102 is unlikely that Mycobacterium is capable of endospore formation.

103 leaves Pro-sigma(K) during Bacillus subtilis endospore formation.

104 Endospores formed by Bacillus subtilis are encased in a

105 e intensively studied, genetically tractable endospore-former, Bacillus subtilis, is an ideal subject

106 Unlike most endospore formers, Epulopiscium partitions only a small

107 entogenic clostridia are strictly anaerobic, endospore forming bacteria that produce a large array of

108 The endospore forming bacterium Bacillus anthracis causes le

109 0A that is highly conserved among species of endospore-forming Bacillus and Clostridium and which enc

110 of cellular propagation that originates with endospore-forming Bacillus and Clostridium spp., which r

111 Fifteen endospore-forming Bacillus species were confirmed in a s

112 of information rich Raman fingerprints from endospore-forming bacteria belonging to the genera Bacil

113 Thirty-six strains of aerobic endospore-forming bacteria confirmed by polyphasic taxon

114 Many endospore-forming bacteria embed alanine racemases into

115 The endospore-forming bacteria have persisted on earth perha

116 lis were present in all of the Gram-positive endospore-forming bacteria whose genome has been sequenc

117 SpoIIID is evolutionarily conserved in endospore-forming bacteria, and it activates or represse

118 etic position, among low G + C Gram-positive endospore-forming bacteria, and the remarkable morpholog

119 sK/SpoIIIE paralogues is not conserved among endospore-forming bacteria, but is highly conserved with

120 Thirty-six strains of aerobic endospore-forming bacteria, consisting of six Bacillus s

121 ine proteases that is highly conserved among endospore-forming bacteria, contributes to SASP degradat

122 D265 and Y264 are conserved among endospore-forming bacteria, raising the possibility that

123 Unlike most endospore-forming bacteria, sporulation is an obligate p

124 Using gene conservation among endospore-forming bacteria, we identified eight previous

125 Since SpoIIID is conserved only in endospore-forming bacteria, which include important path

126 m polyspora and Clostridium lentocellum, are endospore-forming bacteria, which raises the possibility

127 fspring was the ancestor of all contemporary endospore-forming bacteria.

128 ution of the sporulation network in multiple endospore-forming bacteria.

129 at separates forespores from mother cells in endospore-forming bacteria.

130 pressed during sporulation as it is in other endospore-forming bacteria.

131 omologous protein from the distantly related endospore-forming bacterium Clostridium acetobutylicum,

132 om the genome of the closely related but not endospore-forming bacterium Listeria monocytogenes, ther

133 Bacillus anthracis is an endospore-forming bacterium that causes inhalational ant

134 Pasteuria penetrans is a gram-positive, endospore-forming eubacterium that apparently is a membe

135 viously sent to the FDOH laboratory, 56 were endospore-forming gram-positive rods and only 7 grew on

136 yticum lentocellum DSM 5427 is an anaerobic, endospore-forming member of the Firmicutes.

137 nt Metabacterium polyspora is an uncultured, endospore-forming member of the Firmicutes.

138 Sporulation in the model endospore-forming organism Bacillus subtilis proceeds vi

139 Bacillus subtilis, a Gram-positive, endospore-forming soil bacterium, was grown in media mad

140 Certain endospore-forming soil dwelling bacteria are important h

141 (G) regulons that are widely conserved among endospore-forming species but are absent from closely re

142 ncharacterized genes that are enriched among endospore-forming species.

143 is regulated differently from that of other endospore-forming species.

144 confirmed the close relationship between the endospore-forming surgeonfish symbionts characterized he

145 The ability of the endospore-forming, gram-positive bacterium Bacillus anth

146 tridium sp. strain BNL1100, a Gram-positive, endospore-forming, lignocellulolytic bacterium isolated

147 y fatal disease caused by the gram-positive, endospore-forming, rod-shaped bacterium Bacillus anthrac

148 lysis of Metabacterium polyspora, a multiple-endospore-forming, uncultivated inhabitant of guinea pig

149 Using endospores from both the parental strain B. anthracis St

150 oximately 23-34 A would allow passage of the endospore germinants, alanine or inosine but not degrada

151 Upon inoculation into the host the endospores germinate and outgrow into vegetative bacilli

152 in the infectious process Bacillus anthracis endospores germinate and outgrow into vegetative bacilli

153 minant sensors, was shown to be required for endospore germination in the presence of macrophages and

154 A current model of B. anthracis endospore germination is presented.

155 in Bacillus anthracis that is important for endospore germination triggered by two distinct germinat

156 to monitor the kinetics of Bacillus subtilis endospore germination.

157 erical structures in infected hosts, produce endospores, have not been cultured, and possess mitochon

158 ed upon macrophage infection by B. anthracis endospores; however, ONOO(-) does not appear to exhibit

159 On the basis of putative nuclei and endospores, Huldtgren et al. propose that embryo-like Do

160 The conversion of a growing cell into an endospore in Bacillus subtilis involves a phagocytic-lik

161 the cell surface during sporogony and in the endospore in mature spores.

162 as presented that the spores were similar to endospores in ultrastructure, in heat resistance and in

163 ghly conserved only among bacteria that form endospores, including several important human pathogens.

164 gh-resolution native structures of bacterial endospores, including the exosporium and spore coats of

165 technique is capable of identifying anthrax endospores inside a sealed paper envelope.

166 tylase has been localized to the plasmalemma-endospore interface.

167 The endospore is known to contain chitin, and a putative gly

168 A major structural element of bacterial endospores is a peptidoglycan (PG) wall.

169 photolesion found in UV-irradiated bacterial endospores is a thymine dimer, 5-thyminyl-5,6-dihydrothy

170 The outer membrane of endospores is surrounded by the densely packed endospore

171 The capacity to form endospores is unique to certain members of the low-G+C g

172 o its spherical shape, containing hundred of endospores, it was thought to be closely related to the

173 The Bacillus anthracis endospore loses resistance properties during germination

174 ivation mutant stalled in sporulation during endospore maturation, exhibiting engulfment and partial

175 formation of a highly desiccation-resistant endospore might serve as a logical osmostress escape rou

176 illus anthracis includes both vegetative and endospore morphologies which alternate based on nutrient

177 phenotypes (aerobic, anaerobic, facultative, endospore, motility and Gram negative) from 11,969 uniqu

178 Upon infection, germination of endospores occurs during their internalization within th

179 , which were trained to discriminate between endospores of 66 strains from 13 Bacillus and Bacillus-r

180 pathway in microbial killing, the ability of endospores of B. anthracis to regulate production of thi

181 The endospores of Bacillus anthracis are the infectious part

182 ds are required for efficient germination of endospores of Bacillus anthracis DeltaSterne, a plasmidl

183 The peptidoglycan cortex of endospores of Bacillus species is required for maintenan

184 Endospores of Bacillus subtilis are encased in a thick,

185 Endospores of Bacillus subtilis are enclosed in a protei

186 istic mass spectra from individual bacterial endospores of Bacillus subtilis var. niger were obtained

187 x, an often fatal infection, is initiated by endospores of the bacterium Bacillus anthracis, which ar

188 Germination and outgrowth of endospores of the Gram-positive bacterium Bacillus subti

189 d that retention of SOWgp on the surfaces of endospores of the mutant strain in the presence of high

190 imit for B. anthracis was found to be 50,000 endospores, on the basis of the GC/MS detection limits f

191 spherules without endospores, a germinating endospore, or thick-walled hyphal cells.

192 itiated by transcriptional activation during endospore outgrowth.

193 ls in a given population produced one or two endospores per mother cell.

194 most likely xylophagic amitochondriates), an endospore (probably of the filamentous intestinal bacter

195 Upon entry into a host, endospores rapidly differentiate into vegetative bacilli

196 e that efficient germination of B. anthracis endospores requires multipartite signals and that gerS-e

197 ybridizing RNA from the developing spherules-endospores (SEs) and hyphae correlated with the appearan

198 Bacterial spores (endospores), such as those of the pathogens Clostridium

199 ipicolinate (a marker molecule for bacterial endospores, such as Bacillus subtilis and Bacillus anthr

200 A short incubation of bacillus endospore suspensions with ThT, under ambient conditions

201 cillus anthracis forms metabolically dormant endospores that upon germination can cause lethal anthra

202 etely eliminated the ability of B. anthracis endospores to respond to amino-acid and inosine-dependen

203 The endospores, together with the urease and additional mate

204 a rapid analysis system in term of Bacillus endospore typing.

205 macrophages (RAW264.7 cells) to B. anthracis endospores up-regulated the expression of NOS 2 12 h aft

206 f primary murine macrophages to B. anthracis endospores upregulated NOS 2 concomitant with an .NO-dep

207 nthracis Sterne and plasmidless Delta-Sterne endospores was dramatically enhanced in RAW264.7 macroph

208 while germination of nonpathogenic Bacillus endospores was not.

209 acrophage cultures of B. anthracis gerH-null endospores was restored by complementation in trans with

210 Mass spectra of individual Bacillus endospores were measured with a bipolar aerosol time-of-

211 In the populations studied, mature endospores were seen only at night and the majority of c

212 e-Guerin produce a type of spore known as an endospore, which had been observed only in the low G+C g

213 ler cell (forespore) differentiates into the endospore, while the larger cell (mother cell) becomes a

214 e its reproductive potential and supply each endospore with at least one complete copy of the genome.

215 ide an effective and rapid means of staining endospores without the inconvenience of pre- or posttrea