ライフサイエンスコーパス: endothelia

1 ts involved in the maintenance of functional endothelia.

2 TFIID was the converse of YY1, in different endothelia.

3 ow different patterns of binding between the endothelia.

4 sulfate on the luminal surface of capillary endothelia.

5 characterized by retracted cells and thinned endothelia.

6 and abundant staining for COX-2 in infected endothelia.

7 rine, mammary, placenta, and coronary artery endothelia.

8 ce/differentiation of central nervous system endothelia.

9 , is expressed in the vascular and lymphatic endothelia.

10 resulted in increased adhesion to activated endothelia.

11 sive signal for PMN binding to microvascular endothelia.

12 rcellular junctions of various epithelia and endothelia.

13 ls in tubules, whereas Tie-2 is expressed by endothelia.

14 d channels are also described in fenestrated endothelia.

15 and stellate cells, but not from sinusoidal endothelia.

16 is through the VEGFR-3 receptor on lymphatic endothelia.

17 ein of caveolae membranes in fibroblasts and endothelia.

18 and enter Kupffer cells, but not sinusoidal endothelia.

19 rptive endocytosis and transcytosis in brain endothelia.

20 e ischemic injury to neurons, microglia, and endothelia.

21 ally be involved in their arrest on inflamed endothelia.

22 d descending thin limbs as well as capillary endothelia.

23 which mimics adhesion of lymphocytes to CNS endothelia.

24 ng limb of Henle epithelia and in vasa recta endothelia.

25 lining cells, portal tract, and central vein endothelia.

26 ed in erythrocytes and various epithelia and endothelia.

27 ating paracellular transport of large vessel endothelia.

28 ncontact coculture with human umbilical vein endothelia.

29 g metastasis, tumor cells adhere to vascular endothelia.

30 ed endogenous erythropoiesis damage vascular endothelia.

31 the relevance of these findings to arterial endothelia.

32 Cx26 staining was confined to capillary wall endothelia.

33 the alloimmunogenicity of nearby uninfected endothelia.

34 dothelia than on rapidly proliferating tumor endothelia.

35 in expressed strongly in tumor microvascular endothelia.

36 tigens enriched in tumor versus nonmalignant endothelia.

37 o both pulmonary and extrapulmonary vascular endothelia.

38 regulation of tight junction proteins in the endothelia.

39 tes IL-8 production in the LECs of lymphatic endothelia.

40 c significantly diminished albumin uptake by endothelia.

41 ect eNOS expression and activity in vascular endothelia.

42 umber of subepithelial cell types, including endothelia.

43 creases in CD39 mRNA and immunoreactivity on endothelia.

44 -associated endothelia compared with resting endothelia.

45 ssed widely in organ and tumor microvascular endothelia.

46 cross cell plasma membranes in epithelia and endothelia.

47 logies, included (1) angioblasts, (2) mature endothelia, (3) hepatic stellate cell precursors, (4) ma

48 ack morphologically identifiable caveolae in endothelia, adipocytes, smooth muscle cells, skeletal mu

49 t monocyte adhesion on early atherosclerotic endothelia and (2) ILDV peptide interferes with VLA-4 bi

50 channel aquaporin-1 (AQP1) in microvascular endothelia and aquaporin-4 (AQP4) in airway epithelia.

51 Brain microvascular endothelia and brain endothelial cells expressed all of

52 art, by stimulating VEGF expression in tumor endothelia and by recruiting pericytes to neovessels.

53 ry, view tumor cell adhesion to blood vessel endothelia and cancer cell aggregation as corresponding

54 e shown that a soluble activity derived from endothelia and dependent on STAT3 is critical for suppre

55 e elucidate the angiogenic activities of the endothelia and differential interactions with perivascul

56 ents of the basement membranes that separate endothelia and epithelia from the underlying tissue.

57 induced IFN responses specifically in brain endothelia and epithelia of mice.

58 hanical probe-induced micro-wounding of both endothelia and epithelia suggests that ventral lamellipo

59 let-activating factor receptor expression on endothelia and epithelia, which led to reduced bacterial

60 ll mice expressed significantly more PAFr on endothelia and epithelia.

61 eins, critical for maintenance of glomerular endothelia and filtration barrier functional integrity,

62 for leukocyte extravasation through vascular endothelia and for T-cell activation.

63 GH), and placental lactogen are expressed by endothelia and have angiogenic effects.

64 tradiol exposure to internal thoracic artery endothelia and human arterial endothelia in culture stim

65 release from human internal thoracic artery endothelia and human arterial endothelia in culture.

66 Bmx is expressed mainly in arterial endothelia and in myeloid hematopoietic cells.

67 one marrow transplantation, such as vascular endothelia and microglia, to transduce microglial activa

68 displayed leukocyte adhesion to the vascular endothelia and petechial hemorrhages throughout the brai

69 lium attached to the interstitial matrix, to endothelia and phasic lymphatic smooth muscle that act a

70 ccurring along portal tract and central vein endothelia and scattered bile duct epithelial cells and

71 , migration, and differentiation of vascular endothelia and smooth muscle cells.

72 waned in most areas but remained in vascular endothelia and the dentate gyrus.

73 TAT-3 activation were observed, the first in endothelia and the second in hepatocytes.

74 tinel cells of the immune system, leading to endothelia and thrombocyte dysfunction and neurological

75 ch binds to alphavbeta3/5 integrins on tumor endothelia and tumor cells, and a cryptic CendR motif (R

76 aran sulfate purified from primary lymphatic endothelia, and activation of lymphatic endothelial Erk1

77 by oligodendrocytes, neurons, microglia, and endothelia, and MHC class II is expressed only by microg

78 types of mammalian cells including cerebral endothelia, and quantified leptin binding and endocytosi

79 on was inhibited in Ndst1-silenced lymphatic endothelia, and scratch-assay responses to VEGF-C and FG

80 actin dynamics, biomechanical properties of endothelia, and signaling pathways, such as GTPase activ

81 on neutrophils, smooth muscle, hepatocytes, endothelia, and some epithelia.

82 31- and Tie-2-positive peritubular capillary endothelia, and some of the alpha SMA-positive cells exp

83 ntrolling the interaction among tumor cells, endothelia, and stromal matrix.

84 s (PMN, neutrophils) migrate across vascular endothelia, and such transmigration has the potential to

85 channel aquaporin-1 (AQP1) in microvascular endothelia, AQP4 in airway epithelia, and AQP5 at the ap

86 These data indicate that human endothelia are able to produce active vitamin D.

87 osal tissue, such as the lung and intestine, endothelia are anatomically positioned in close proximit

88 ulation of plasmalemmal vesicles of vascular endothelia are described.

89 Barrier functions across epithelia and endothelia are essential for homeostatic tissue regulati

90 In blood vessels, endothelia are submitted to constant shear effects and a

91 These data define STAT3 signaling within endothelia as a critical antiinflammatory mediator and p

92 fluorescence of MitoTracker in microvascular endothelia as a result of reduced mitochondrial mass.

93 ules and activate macrophages, NK cells, and endothelia as well as participate in organ-specific auto

94 studied whether PTPmu, in pulmonary vascular endothelia, associates with and/or regulates both the ty

95 Expression of ZO-1 in WT endothelia at P14 was diffuse and localized to the basol

96 ial cells closely resemble lymphatic (valve) endothelia at the molecular level, suggesting plasticity

97 Notwithstanding endothelia being non-excitable in nature, the hypothesis

98 atenin-Dll4/Notch signaling cascade in tumor endothelia, blocking an angiogenic and favoring a quiesc

99 ogically active ET ligand, begins in cardiac endothelia, both arterial and endocardial, at initiation

100 ontrast, connexin43 was undetectable in most endothelia but extremely abundant in small numbers of ce

101 aring of globotriaosylceramide from vascular endothelia but little effect on proteinuria or progressi

102 cadherin-10, is expressed in BBB and retinal endothelia, but not in the leaky microvessels of brain c

103 irectly acting on the vascular and lymphatic endothelia, but they also can affect distal sites.

104 ptor (CysLT(1)) is induced in human vascular endothelia by interleukin-1beta.

105 GFBP2) secreted by metastatic cells recruits endothelia by modulating IGF1-mediated activation of the

106 Endothelia-cell injury may result in an imbalance in end

107 hages but not by myogenic cells or capillary endothelia cells in injured muscles.

108 ys an important role in tight junction among endothelia cells, leukocyte trafficking, and immune resp

109 nduced to highest levels in tumor-associated endothelia compared with resting endothelia.

110 -regulation of PAFr on chronically activated endothelia could contribute to increased bacterial invas

111 In other studies, lymphatic endothelia cultured ex vivo from Ndst1 gene-targeted mic

112 Corneal endothelia derived from mice and humans were treated wit

113 Using gene profiling, we identified that the endothelia-derived chemokine ligand CXCL10 mediated beha

114 renal Ent1 and Adora2b expressed on vascular endothelia effectively prevented a postischemic no-reflo

115 ms, the kidney and the liver, and cells from endothelia, epithelia, and the bone marrow compartment.

116 Swine aortic arch endothelia exhibited elevated ROS, NOX4, HIF-1alpha, and

117 IFN-gamma thus alters gene expression by endothelia exposed to B. burgdorferi in a manner that pr

118 in vivo in mouse and swine aortic arch (AA) endothelia exposed to chronic disturbed flow, and in mou

119 uman lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.

120 ng cell lines and human brain microcapillary endothelia expressing high levels of endogenous receptor

121 beta4BM in hCLCA1, which is not expressed in endothelia, failed to interact with beta4 integrin.

122 pecifically, as the ureteric bud bifurcates, endothelia form across the bifurcation site as the cap m

123 In the absence of the dorsal aorta, endothelia from an alternate source are recruited by pod

124 n homogenates or the particulate fraction of endothelia from bovine or rabbit.

125 d function of the tumor vasculature and that endothelia from different tissues vary in their ability

126 enosine monophosphate (cAMP) was measured in endothelia from fresh and incubated corneas, and adenyly

127 n were similar in primary cultures of aortic endothelia from wild-type and from AQP1-null mice, cell

128 Retinal endothelia have the capacity to express AQP1, though int

129 TLR) 4 expressed in human lung microvascular endothelia (HMVEC-Ls) to open the paracellular pathway t

130 of Adora2b in tubular epithelia or vascular endothelia implicated endothelial Adora2b signaling in p

131 ) in culture, and is expressed on continuous endothelia in all tissues.

132 present not only in neurons, but in cerebral endothelia in Alzheimer's disease caused by certain APP

133 of IL-4 signaling, by tumor cells and tumor endothelia in CNS lymphomas.

134 horacic artery endothelia and human arterial endothelia in culture stimulated NO release within secon

135 horacic artery endothelia and human arterial endothelia in culture.

136 to identify peptides that bound the vascular endothelia in diseased and wild-type mice.

137 We found that vascular endothelia in inflamed areas of lacrimal gland expressed

138 ular matrix that underlies all epithelia and endothelia in multicellular animals.

139 lasma extravasation in postcapillary venular endothelia in NEP-/- mice, which was reversed by recombi

140 knockout of the receptor for ANP in vascular endothelia in order to distinguish the effects of ANP-de

141 signaling in the maintenance of neurons and endothelia in the central nervous system.

142 ot all, of the thoracic and abdominal aortic endothelia in the form of maculae at cell-cell appositio

143 elevation that matched beta-actin-expressing endothelia in the vascular wall.

144 rins, blocked the adhesion of these cells to endothelia in vitro and in vivo as well as their homing

145 the adhesion of mural cells to proliferating endothelia in vitro and in vivo, thereby inducing apopto

146 cells proliferated faster and produced more endothelia in vivo than their otherwise isogenic trisomi

147 ial for transcytosis of ligands across tight endothelia, including the blood-brain barrier.

148 tion in which FRNK expression in microvessel endothelia increased vascular permeability.

149 dynamic forces are detected and converted by endothelia into a sequence of biological and even pathol

150 on page 1234) reports how TLR2 expression by endothelia is locally upregulated by the action of activ

151 IV (DPP IV) expressed on rat lung capillary endothelia is shown here to be an adhesion receptor for

152 gic nerve terminals and by NOS-3 in vascular endothelia, is probably a physiological vasodilator in t

153 whether the gene is transcribed in different endothelia, is related to the balance between activating

154 dissemination is bacterial interaction with endothelia lining blood vessels, which is physically cha

155 Here we tested the hypothesis that endothelia lining these vessels can be harnessed to crea

156 e the replacement of MAdCAM-1 by PNAd in HEV endothelia, lymphocytes could efficiently home to PPs in

157 rtension as well as other disorders in which endothelia may be damaged.

158 reciprocal interaction between podocytes and endothelia may provide opportunities for therapeutic int

159 The antigen cross-presentation ability of endothelia may therefore contribute to the specificity o

160 rare (<5%) cells, such as Tie2:Cre(+) brain endothelia/microglia (76% validated by expression patter

161 ion in different tissues--including vascular endothelia, myeloid cells, and hepatocytes--revealed a s

162 Systematic deletion of HIF1A in the lungs, endothelia, myeloid cells, or pulmonary epithelia linked

163 power of phage display for mapping vascular endothelia natively in tissue and for achieving vascular

164 In endothelia, NO is synthesized by endothelial NO synthase

165 ere Gpr124 conditional knockout (CKO) in the endothelia of adult mice did not affect homeostatic BBB

166 enomenon shared by human arterial and venous endothelia of both fetal and adult origin.

167 The endothelia of Col12a1(-/-), Col14a1(-/-), and compound C

168 led a spread of phenotypic diversity between endothelia of distinct developmental origins and organs.

169 RNA-Seq splicing data from the corneal endothelia of FECD patients and controls reveal hundreds

170 gene with overexpression of cNOS protein in endothelia of gastric mucosal vessels.

171 3 was constitutively present in the vascular endothelia of large and small vessels.

172 Expression of ICAM-1 in aortic endothelia of LOTG mice was increased severalfold.

173 The endothelia of normal and Fuchs'-affected corneas were st

174 xhibits limited capacity to divide while the endothelia of other species, such as rabbit, divide in v

175 dothelial venules but is also present on the endothelia of other vessels.

176 Metastatic tumor cells attached to the endothelia of pulmonary pre-capillary arterioles and cap

177 heir cognate antigens for targeting vascular endothelia of specific organs in vivo.

178 aveolae and transendothelial channels in the endothelia of these vascular beds.

179 irculation and that specifically bind to the endothelia of tumor blood vessels.

180 ce of infected erythrocytes to microvascular endothelia of various organs, including the placenta, th

181 , was increased approximately 2-fold each in endothelia, oligodendroglia, astrocytes, and axons of th

182 intercellular adhesion molecules (ICAMs) on endothelia or antigen-presenting cells.

183 When endothelia or astrocytes are plated onto these substrate

184 onto these substrates, confluent domains of endothelia or astrocytes grow on the poly(L-lysine) doma

185 cell type sporozoites use for extravasation, endothelia or Kupffer cells, we quantified sporozoite ad

186 Additional studies in endothelia overexpressing full-length A2BR revealed func

187 In human and rabbit endothelia, p53 and p16INK4 were localized to the cytopl

188 ng in line with its downregulation in glioma endothelia, potentially implicating Cyp1b1 in other brai

189 While both viruses infect microglia and endothelia primarily in the white matter areas of the CN

190 timuli (LPS, IL-1alpha, TNF-alpha, hypoxia), endothelia produce and secrete a small, stable epithelia

191 lineage restriction to hepatoblasts, mature endothelia produced differentiation into hepatocytes, an

192 We hypothesized that adenosine signaling to endothelia provides a paracrine loop for regulated expre

193 ly described mechanism of VEGF inhibition in endothelia required the release of VEGF-R1 intracellular

194 anotransduction mechanisms by which vascular endothelia respond to local atherorelevant hemodynamics

195 Fluid flow across various endothelia results in a variety of intracellular and ext

196 However, vascular endothelia, retinal pigment epithelia, Muller cells, and

197 on of the genes expressed in lung and kidney endothelia revealed numerous differences.

198 Additional studies in confluent endothelia revealed that gravin functionally couples to

199 r on erythrocytes (strain ThCD59(RBC)) or on endothelia (strain ThCD59(END)).

200 disturbed flow, and in mouse carotid artery endothelia subjected to surgically induced acute disturb

201 the permeation of xenobiotics through tight endothelia such as the blood-brain barrier.

202 tion of lytic injury to uninfected bystander endothelia, suggesting multiple mechanisms by which this

203 , the presence of LYVE-1 in liver sinusoidal endothelia suggests that LYVE-1 has functions beyond the

204 n any other reproductive or non-reproductive endothelia tested, ERbeta was augmented by pregnancy in

205 a radiosensitizing effect on normal cardiac endothelia than on rapidly proliferating tumor endotheli

206 angiogenic growth factors or on neighboring endothelia that are affected by these agents.

207 d in both neurons and cerebral microvascular endothelia that binds Abeta.

208 biting the antiapoptotic effects of Ang-1 on endothelia that express the Tie-2 receptor.

209 elated with heightened permeability of other endothelia, the objective of this study was to test the

210 re compared in both human and rabbit corneal endothelia: the tumor suppressors, pRb, p53, and p16INK4

211 is widely expressed by differentiating renal endothelia, this study is consistent with the hypothesis

212 which promote chemotaxis of granulocytes and endothelia through binding to CXC Receptor 2.

213 that CD44 mediates several of its effects on endothelia through modulation of adhesion protein expres

214 e paracellular pathway in pulmonary vascular endothelia through protein tyrosine phosphorylation.

215 cular meshwork (TM) and Schlemm's canal (SC) endothelia to aqueous humor outflow resistance.

216 differences between tumor and normal tissue endothelia to induce acute vascular shutdown in tumors.

217 ERTK-expressing monocytes migrate across the endothelia to localize into tissue sites and regional ly

218 Astroglia interact with cerebral endothelia to maintain the blood-brain barrier.

219 ts of the extracellular matrix can stimulate endothelia to trigger recognition of injury in the initi

220 Fc molecules by HULEC-5A lung microvascular endothelia transfected with GFP fusion proteins of human

221 complexes too large to cross the continuous endothelia under physiological conditions.

222 specifically to the inflamed carotid artery endothelia under physiological flow conditions and to be

223 B. burgdorferi exploits Fn to interact with endothelia under physiological shear stress, using recen

224 cells such as leukocytes and platelets with endothelia under vascular shear stress requires mechanic

225 conditionally deleted in restricted vascular endothelia using a novel endothelial Cre transgenic line

226 sic PKA demonstrated an inhibitory effect on endothelia vascular-like structure formation.

227 sin cell adhesion molecule 1 on the DLN high endothelia venules, and production of IL-6 and CC chemok

228 nteraction of platelets with neutrophils and endothelia was associated with TXA(2) formation, with de

229 ular localization of PMP22 in cultured brain endothelia was confirmed by internalization with ZO-1 af

230 rditis, the upregulation of PD-L1 on cardiac endothelia was dependent on T-cell-derived interferon-ga

231 g perfusion in mice with genetically labeled endothelia, we compared peritubular capillary number and

232 icroscopy, rat aortic and pulmonary arterial endothelia were found to express all 3 connexin types, w

233 All three endothelia were screened for transcription factors that

234 Pmu is expressed in human pulmonary vascular endothelia where it directly binds to VE-cadherin and re

235 channel protein expressed widely in vascular endothelia, where it increases cell membrane water perme

236 xpressed in, and secreted from, the vascular endothelia will be endocytosed by underlying neurons and

237 o incur cytoxic effects and apoptosis of BBB endothelia with an impairment of barrier functionality.

238 Treatment of human brain endothelia with glutamate or selective, mGluR group I or

239 ly attenuated by pretreatment of human brain endothelia with selective mGluR antagonists.

240 ons were present in the glomerular capillary endothelia without any associated inflammatory response.