ライフサイエンスコーパス: energy metabolism

1 l activity, vascular tone, inflammation, and energy metabolism.

2 ations, and as a model for algal biofuel and energy metabolism.

3 r gamma (PPARgamma) is a master regulator of energy metabolism.

4 egulator of neuronal function and whole-body energy metabolism.

5 om lysosomes controls cellular clearance and energy metabolism.

6 hat aging and cancer are diseases related to energy metabolism.

7 vels, reactive oxygen species production and energy metabolism.

8 tigating human infant brain function and its energy metabolism.

9 ut cellular oxygen utilisation and therefore energy metabolism.

10 in the control of adipose tissue biology and energy metabolism.

11 n that catalyzes the reduction of oxygen for energy metabolism.

12 ys, which were reflective of an imbalance in energy metabolism.

13 ht, mussels stimulated seagrass nitrogen and energy metabolism.

14 et-induced changes of the gut microbiota and energy metabolism.

15 ssibility to track amyloidogenesis and brain energy metabolism.

16 d the diseases associated with mitochondrial energy metabolism.

17 h alters molecular and functional indexes of energy metabolism.

18 cterized by down-regulated genes involved in energy metabolism.

19 NSun3 and link m(5)C RNA modifications with energy metabolism.

20 hormones that regulate different aspects of energy metabolism.

21 ment, followed by a changeover to lipids for energy metabolism.

22 of PC1 expression profoundly alters cellular energy metabolism.

23 related to the metabolism of amino acids and energy metabolism.

24 owning or beiging of adipose tissue, and (f) energy metabolism.

25 lation by modulating AMPK-mediated adipocyte energy metabolism.

26 uding Igf1r and Nr4a2, which are involved in energy metabolism.

27 IEX-1), a downstream target of NF-kappaB, in energy metabolism.

28 g organ development, cell proliferation, and energy metabolism.

29 cell signaling, carbon/nitrogen storage, and energy metabolism.

30 alterations of critical enzymes that govern energy metabolism.

31 hment by regulating membrane trafficking and energy metabolism.

32 SERCA)2a signalling and decreased myocardial energy metabolism.

33 elucidating the molecular network regulating energy metabolism.

34 nd enolase, all of which are responsible for energy metabolism.

35 oteins and other protein species involved in energy metabolism.

36 -oxidation spiral, and thus is important for energy metabolism.

37 hnospiraceae, which are dominant families in energy metabolism.

38 y and upregulated AKT-SERCA2a signalling and energy metabolism.

39 T axis may favour longevity without altering energy metabolism.

40 dation to the electron transfer chain and to energy metabolism.

41 vity to leptin's effects on both feeding and energy metabolism.

42 two periods of high fat feeding, we examined energy metabolism.

43 ical exposure in the regulation of lipid and energy metabolism.

44 hat MFN2 is needed to maintain mitochondrial energy metabolism.

45 nse, photosynthesis, nutrient metabolism and energy metabolism.

46 as elderly T2Ds have impaired fasting muscle energy metabolism.

47 ailability of iron is important for cellular energy metabolism.

48 ensing enzyme and a key player in regulating energy metabolism.

49 g diastolic function, vascular function, and energy metabolism.

50 lin5 overexpression on cardiac lipolysis and energy metabolism.

51 anisms of cardioprotection and modulation of energy metabolism.

52 f the p53 family, has been shown to regulate energy metabolism.

53 s via secreted factors to influence systemic energy metabolism.

54 ons in C1QBP cause a defect in mitochondrial energy metabolism.

55 f genes related to the transport process and energy metabolism.

56 ermal and/or peripheral changes in lipid and energy metabolism.

57 elevant SCFA mixtures on human substrate and energy metabolism.

58 treatment of diseases that have dysregulated energy metabolism.

59 is that regulates both aerobic and anaerobic energy metabolism.

60 ve method for studying the effects of TBI on energy metabolism.

61 ns after fertilization; protein-, lipid- and energy-metabolism.

62 led with increased OGA expression reprograms energy metabolism, a finding that has potential implicat

63 Here we describe a venom component targeting energy metabolism, a radically different mechanism.

64 ression, resisting cell death, reprogramming energy metabolism, acquiring genomic instability, and re

65 We compare energy metabolism across the life cycle of malaria paras

66 Vps34 inhibition alters cellular energy metabolism, activating the AMPK pathway in liver

67 a and basal bodies, ribosome biogenesis, and energy metabolism, all had distinct signatures of coexpr

68 g the coupling between neuronal activity and energy metabolism, also regulates the expression of BDNF

69 ic effect of insulin that is associated with energy metabolism alterations.

70 30- to 60-min recordings with (18)F-FDG for energy metabolism and (18)F-florbetaben for amyloidosis.

71 into the functions of the hepatopancreas in energy metabolism and biological processes pertaining to

72 cates alterations in brain regional cellular energy metabolism and blood flow in schizophrenia.

73 Energy metabolism and body-composition metrics, appetite

74 tes several liver functions such as drug and energy metabolism and cell growth or death, which are of

75 essential roles in most living organisms for energy metabolism and cell-to-cell communication.

76 ogether, these results suggest links between energy metabolism and cellular physiology, morphology, a

77 We conclude that disruption of energy metabolism and depletion of glutathione contribut

78 indicates that interactions between altered energy metabolism and disruptions in the circadian clock

79 To further delineate the energy metabolism and drug metabolism crosstalk in this

80 thus reveal an important connection between energy metabolism and ECM assembly.

81 ific oxidoreductase critically important for energy metabolism and execution of the caspase-independe

82 changes to metabolic processes, and indeed, energy metabolism and functional activation are fully in

83 for clinically relevant (13)C MRS studies of energy metabolism and further provides opportunities for

84 ferator-activated receptors (PPARs) regulate energy metabolism and hence are therapeutic targets in m

85 suggesting a role for keratins in colonocyte energy metabolism and homeostasis.

86 c and hepatic role of AHR in fatty liver and energy metabolism and identified the endocrine factor th

87 PPARgamma modulates energy metabolism and inflammation.

88 hypothesized that formate might affect both energy metabolism and microaerobic survival in C. jejuni

89 vivo that was associated with alterations in energy metabolism and mitochondrial dysfunction.

90 light the role of TRAP1 in the regulation of energy metabolism and mitochondrial quality control.

91 microRNA-binding sites of genes involved in energy metabolism and muscle structure.

92 dria also have a seminal influence on cells' energy metabolism and on photosynthetic reactions.

93 se cellular processes, that is, translation, energy metabolism and one carbon metabolism.

94 ermediates in the most relevant pathways for energy metabolism and oxidative imbalance in exponential

95 es (AMA) that recognize proteins involved in energy metabolism and oxidative stress, raising the poss

96 uction of a myokine, irisin, improves kidney energy metabolism and prevents kidney damage.

97 y interacting global regulator of carbon and energy metabolism and probably of other physiological pr

98 Results suggest that changes in energy metabolism and processes related to neuroplastici

99 eurodegenerative diseases, lead to disrupted energy metabolism and production of damaging reactive ox

100 of SIRT7 and NRF1 and is coupled to cellular energy metabolism and proliferation.

101 of molecular mechanisms, including cellular energy metabolism and respiration.

102 sion of new Penicillium proteins involved in energy metabolism and some protein species related to re

103 To study the relationship between energy metabolism and sperm motility we used dissolution

104 Proteins involved in carbon metabolism, energy metabolism and stress response were frequently de

105 Our data implicate mitochondrial energy metabolism and the antioxidant defense system as

106 ng evidence has shown the close link between energy metabolism and the differentiation, function, and

107 To study astroglial energy metabolism and the directionality of lactate flux

108 ulfide toxicity, causing inhibited oxidative energy metabolism and tissue degradation.

109 mechanism by long non-coding RNAs to control energy metabolism and tumor development.FoxO are commonl

110 s (GCs) are important regulators of systemic energy metabolism, and aberrant GC action is linked to m

111 Mitochondria are the nexus of energy metabolism, and consequently their dysfunction ha

112 ighly enriched in transcription factor (TF), energy metabolism, and developmental signaling genes.

113 y, in low light mussels impeded nitrogen and energy metabolism, and enhanced responses against sulfid

114 ion rapidly increases hepatic lipid storage, energy metabolism, and insulin resistance.

115 and adipose tissues, bile acid composition, energy metabolism, and messenger RNA and protein express

116 logical process dependent on cell viability, energy metabolism, and temperature, receptor clustering

117 oxidized form NAD(+) have a central role in energy metabolism, and their concentrations are often co

118 as exercise place an unusual demand on liver energy metabolism, and this demand induces a state of en

119 hought to be due, in part, to modulations in energy metabolism, appetite, and energy intake.

120 Defects in skeletal muscle energy metabolism are indicative of systemic disorders s

121 duction, cell signaling and development, and energy metabolism are likely to be targets of positive n

122 Perturbations in cardiac energy metabolism are major contributors to a number of

123 eptor CAR (NR1I3) regulates hepatic drug and energy metabolism as well as cell fate.

124 TH) have similar effects on carbohydrate and energy metabolism as well as overlapping transcriptional

125 eptor (CAR) regulates hepatic xenobiotic and energy metabolism, as well as promotes cell growth and h

126 AH pathogenesis, and alterations in cellular energy metabolism associate with PAH.

127 , which may be due to the modulation on cell energy metabolism at both metabolic and transcriptional

128 Due to its ubiquitous role in the energy metabolism, both the oxidation and reduction of t

129 e improvement not only of mitochondrial cell energy metabolism but also of glucose homeostasis.

130 They share a common energy metabolism but represent a heterogeneous group wi

131 istones have been shown to regulate cellular energy metabolism, but their role in white adipose tissu

132 ma coactivator 1-alpha (PGC1alpha) regulates energy metabolism by directly interacting with transcrip

133 In vitro, Astragaloside IV regulated energy metabolism by increasing ATP production and enhan

134 SLN overexpression (Sln(OE)) mice to explore energy metabolism by pair feeding (fixed calories) and h

135 nvasive methods with which regional flow and energy metabolism can be repeatedly investigated to demo

136 Macrophage energy metabolism can significantly influence macrophage

137 ptional downregulation of pathways mediating energy metabolism, cell cycle, and B cell receptor signa

138 The affected pathways included energy metabolism, cell signaling, and immune responses.

139 not only multiple functions in vertebrates (energy metabolism, central nervous system function, seas

140 to the mass transfer limitation influencing energy metabolism (CO/H2 oxidation for cofactor generati

141 file, histology, and markers of dysregulated energy metabolism compared with controls.

142 r fundamental physiological processes (e.g., energy metabolism), compromising an organism's capacity

143 ies at the crossroads of glucose, lipid, and energy metabolism, control of its availability by G3PP a

144 Altered energy metabolism could underlie this association.

145 Under cellular stress that stimulates energy metabolism, COX7AR is induced and incorporated in

146 co-regulates the expressions of mediators of energy metabolism (cytochrome c oxidase) and mediators o

147 id insensitive 3(ABI3), the cytoskeleton and energy metabolism decreased in the dormant stage.

148 xtent to which normal and pathophysiological energy metabolism depend on the GC receptor (GR) in adip

149 cted with the induction of genes involved in energy metabolism, detoxification and innate immunity.

150 However, the effects of this drug on energy metabolism due to NAD(+) depletion were never des

151 ulation of enzymes involved in mitochondrial energy metabolism during growth at 37 degrees C compared

152 new insight into the regulation of cellular energy metabolism during hypoxic stress and the potentia

153 cellular nutrient sensing and the control of energy metabolism during Legionella infection.

154 scriptomic analysis revealed changes of host energy metabolism during the course of infection that ar

155 Because human energy metabolism evolved to favor adiposity over leanne

156 fied under NaOCl stress that are involved in energy metabolism, fatty acid and mycolic acid biosynthe

157 ata suggest that empagliflozin, by switching energy metabolism from carbohydrate to lipid utilization

158 cted functional connectivity (FC) with local energy metabolism from fMRI and positron emission tomogr

159 naptic activity promotes a shift of neuronal energy metabolism from oxidative phosphorylation toward

160 Differential expression of energy metabolism genes, which indicated increased gluco

161 etformin-induced impairment of mitochondrial energy metabolism (glucose oxidation, O2 consumption, an

162 Although regulation of energy metabolism has been linked with multiple disorder

163 However, the effect of LND on central energy metabolism has never been fully characterized.

164 Its function to regulate energy metabolism has recently been reported.

165 and molecular mechanisms that regulate brain energy metabolism, how such mechanisms are altered durin

166 ng partners might be important regulators of energy metabolism in adipose tissue, and potential thera

167 s angiogenesis, cardiovascular activity, and energy metabolism in adulthood.

168 The nature of energy metabolism in apicomplexan parasites has been clo

169 down-regulation of proteins associated with energy metabolism in cardiac hypertrophy.

170 ssible implications for thermoregulation and energy metabolism in drinkers.

171 ework of the genetic and regulatory basis of energy metabolism in fission yeast and beyond, and it pi

172 CCR5 or CCL5 in mice impaired regulation of energy metabolism in hypothalamus.

173 eveals increased ATP production and improved energy metabolism in injured kidneys from mPGC-1alpha mi

174 It is unknown whether lactate contributes to energy metabolism in living tumors.

175 The role of mitochondrial energy metabolism in maintaining lung function is not un

176 studied the effects of irisin deficiency on energy metabolism in mCaROCK1 mice.

177 e cytosol and that pioglitazone may regulate energy metabolism in mitochondria by inhibiting the elec

178 The mechanism by which mitoNEET regulates energy metabolism in mitochondria, however, is not fully

179 tes drug pioglitazone, is a key regulator of energy metabolism in mitochondria.

180 inhibition of FAO catastrophically decreased energy metabolism in MYC-overexpressing TNBC cells and b

181 insulin sensitivity or related substrate and energy metabolism in overweight or obese prediabetic men

182 These findings highlight the implication of energy metabolism in pathophysiological events associate

183 ypothalamic opioid system might also control energy metabolism in peripheral tissues.

184 subtle perturbations of various pathways of energy metabolism in real time.

185 aining LmCOX subunit IV expression and hence energy metabolism in response to stress stimuli such as

186 nvolved in the regulation of skeletal muscle energy metabolism in rodents.

187 istent with substantially preserved neuronal energy metabolism in Sarm1(-/-) mice compared to control

188 K as a direct molecular link between MTX and energy metabolism in skeletal muscle.

189 Our findings highlight a key role for brain energy metabolism in social behavior and point to mitoch

190 ional and experimental approaches to compare energy metabolism in the causative agent of sleeping sic

191 Competing models of mitochondrial energy metabolism in the heart are highly disputed.

192 amic control of mitochondrial biogenesis and energy metabolism in the normal and diseased heart.

193 We conclude that NO can modulate astrocytic energy metabolism in the short term, reversibly, and at

194 nes of evidence for a comprehensive model of energy metabolism in the vertebrate eye.

195 ly targets the altered form of mitochondrial energy metabolism in tumour cells, causing changes in mi

196 oxidative phosphorylation and mitochondrial energy metabolism in vitiligo.

197 re known to be cardioprotective and to alter energy metabolism in vivo NO3(-) action results from its

198 This reveals a novel aspect of neuronal energy metabolism in which activity-dependent glutamate

199 a novel mechanism of reprogramming of cancer energy metabolism in which HuR suppresses miR-199a matur

200 dy, we investigated markers of mitochondrial energy metabolism including the PGC1a axis, and then we

201 lterations in signaling pathways involved in energy metabolism, including glucose uptake and fermenta

202 found elevation of microRNAs associated with energy metabolism, including the miR-29 family, among HP

203 underscore the significance of mitochondrial energy metabolism-independent signals in GIIS regulation

204 focus on pathways related to neural growth, energy metabolism, inflammation, and neuroendocrine resp

205 arkedly improves the anti-tumour activity of energy metabolism inhibitors in mice.

206 formation initiated the investigation of how energy metabolism intervenes in this process.

207 es that house essential pathways involved in energy metabolism, ion homeostasis, signalling and apopt

208 lism, amino acid biosynthesis, fermentation, energy metabolism, iron acquisition, and the stress resp

209 Altered energy metabolism is a cancer hallmark as malignant cell

210 Impairment in energy metabolism is a common trend in Huntington pathog

211 Altered cellular energy metabolism is a hallmark of many diseases, one no

212 Energy metabolism is critical for normal neuronal functi

213 Brain energy metabolism is critical for supporting synaptic fu

214 The control of energy metabolism is fundamental for cell growth and fun

215 Brain energy metabolism is important in almost all neurologica

216 For excess DA levels, a failure in energy metabolism is indicated.

217 Flexibility in energy metabolism is therefore a key mechanism to maximi

218 lin resistance and hyperglycemia for hepatic energy metabolism is yet unclear.

219 age between inflammation, thermogenesis, and energy metabolism, is unclear.

220 e network (DMN), having a high rate of basal energy metabolism, is vulnerable to altered glucose meta

221 ) complex, a key mitochondrial gatekeeper of energy metabolism, leading to an enhanced PDH activity.

222 T2DM is associated with altered cardiac energy metabolism, leading to ectopic lipid accumulation

223 aling contributes to aging and cancer at the energy metabolism level.

224 he expression of genes involved in motility, energy metabolism, lipid metabolism, metal transport, an

225 iratory state and/or substrates that sustain energy metabolism markedly influence the relative contri

226 of ArcA overexpression strains, respiratory energy metabolism may be related to a general preparator

227 However, it is unresolved whether energy metabolism may resultantly regulate major brain f

228 Dysregulated lipid and glucose photoreceptor energy metabolism may therefore be a driving force in ma

229 ains, independent of body weight changes, on energy-metabolism metrics and glycemic control.The study

230 reverses mutation-associated alterations on energy metabolism, mitochondrial biogenesis and restores

231 Furthermore, brain energy metabolism normalised with triheptanoin, that is,

232 Body-wide changes in bioenergetics, i.e., energy metabolism, occur in normal aging and disturbed b

233 ion (FBEB) is an important mechanism for the energy metabolism of anaerobes.

234 t denitrification is inconsequential for the energy metabolism of AOB, but possibly important as a ro

235 nto a small gene family to help regulate the energy metabolism of cells that contain both mitochondri

236 nal bioavailability of oxygen by driving the energy metabolism of colonic epithelial cells (colonocyt

237 able of dynamically simulating the redox and energy metabolism of hepatocytes.

238 (TBI) is known to cause perturbations in the energy metabolism of the brain, but current tests of met

239 vity for many biosynthetic reactions and for energy metabolism of the cell.

240 s, and then analyze the microbial carbon and energy metabolisms of various carbon substrates (e.g., g

241 olled fundamental cellular processes such as energy metabolism, organelle biogenesis and stress respo

242 that it may be a useful probe for examining energy metabolism, particularly in BRAF-mutant melanoma,

243 s gene transcription that is associated with energy metabolism, particularly oxidative phosphorylatio

244 In heart failure (HF), energy metabolism pathway in cardiac muscle changes from

245 between the drug metabolism pathway and the energy metabolism pathway, but little is known about thi

246 be the rate-limiting enzyme of the ketogenic energy metabolism pathway, mitochondrial 3-hydroxy-3-met

247 anscript levels of most genes functioning in energy metabolism pathways are coherently tuned, reflect

248 y, these genes are significantly enriched in energy metabolism pathways.

249 terol efflux via repression of mitochondrial energy metabolism pathways.

250 D), plasma LDL cholesterol levels, and other energy metabolism phenotypes.

251 aptic function, cytoskeletal rearrangements, energy metabolism, phospholipid biosynthesis/metabolism,

252 We conclude that decreasing mitochondrial energy metabolism, possibly through AMPK - PGC-1A pathwa

253 together suggest that aberrant mitochondrial energy metabolism precedes axonal degeneration.

254 de form of vitamin B3 known to enhance brain energy metabolism, prevented the development of a subord

255 tegories, including amino acid biosynthesis, energy metabolism, protein synthesis, transport/binding,

256 ino acids (elevated), metabolites related to energy metabolism (pyruvate and citrate; elevated), and

257 s in physiopathological processes, including energy metabolism, reactive oxygen species (ROS) product

258 ism and physiology in terms of mitochondrial energy metabolism, reactive oxygen species production, g

259 nels depicting systems such as biosynthesis, energy metabolism, regulation and central dogma.

260 In late mouse pregnancy, rhythmicity of energy metabolism-related genes in the muscle followed t

261 ned by a systems-wide shift in expression of energy metabolism-related genes.

262 functions of FGF19 in bile acid, glucose and energy metabolism remain intact.

263 ystem for studying human aging or cancer, in energy metabolism remains elusive.

264 ll molecules that target enzymes involved in energy metabolism remains important yet challenging.

265 ne cells, particularly osteocytes, regulates energy metabolism remains unknown.

266 c-5p and miR-151a-5p) related to hypoxia and energy metabolism respectively.

267 f TRPC1 may alter the regulation of cellular energy metabolism resulting in insulin resistance thereb

268 ously match fluctuating supply and demand in energy metabolism results in nonautonomous time-varying

269 Cellular-resolution imaging of energy metabolism reveals a concurrent elevation of ener

270 lack of success is because of AMPK-mediated energy metabolism rewiring, protecting cancer cell viabi

271 The process requires an efficient energy metabolism, so that although the metal clusters o

272 ontrols on the temperature response of plant energy metabolism, such that a single new function can p

273 l pyruvate uptake do not compromise cellular energy metabolism, suggesting neuronal metabolic flexibi

274 s and experimental data were associated with energy metabolism, terpenoid biosynthesis, fatty acids,

275 alterations in translational regulation and energy metabolism that characterize these patients.

276 ous yeast SNF1 complex are key regulators of energy metabolism that counteract nutrient deficiency an

277 redicted a link between glycerol and central energy metabolism that influences the osmotic stress res

278 ovel approach for inferring EC from neuronal energy metabolism that is ideally suited to study signal

279 Despite being the primary site of energy metabolism, the underlying mechanism on how insul

280 In addition to improved energy metabolism, this protective effect was associated

281 -1 (CB1) plays a crucial role in controlling energy metabolism through central and peripheral mechani

282 le for myelination and maintenance of axonal energy metabolism through export of metabolites, such as

283 cal roles in controlling lipid synthesis and energy metabolism through its enzymatic activity and nuc

284 tabolic and regulatory genes associated with energy metabolism, translation, and cell motility were h

285 anism that couples translational control and energy metabolism, two processes that all viruses depend

286 loss of function leads to reduced control of energy metabolism, ultimately impacting mitochondrial me

287 Thus, IP6K1 regulates energy metabolism via a mechanism that could potentially

288 ve a substantial impact on the regulation of energy metabolism via central and peripheral mechanisms.

289 Finally, energy metabolism was evaluated during a subsequent exer

290 The overall energy metabolism was found to be strikingly robust, and

291 evolution of parameters describing cellular energy metabolism was measured over a wide range of exer

292 Altered energy metabolism was only detectable in pregnant female

293 In this work the role of p62 in energy metabolism was studied in fibroblasts from FTD pa

294 inflammatory chemokine, with a known role in energy metabolism, was identified as a target of RA.

295 To analyze early abnormalities in hepatic energy metabolism, we examined 55 patients with recently

296 umans exhibit augmented postprandial hepatic energy metabolism, whereas elderly T2Ds have impaired fa

297 auses dysfunctional mitochondria and altered energy metabolism, which further leads to systemic oxida

298 melanoma cells causes abnormal regulation of energy metabolism, which in turn allows cancer cells to

299 er transcriptional regulator that integrates energy metabolism with circadian rhythm.

300 Recent studies link changes in energy metabolism with the fate of pluripotent stem cell