ライフサイエンスコーパス: engineering

1 scaffolds for drug delivery and bone tissue engineering.

2 and simulations to mechanobiology and tissue engineering.

3 ctured scaffold design for functional tissue engineering.

4 otential to enable new strategies for genome engineering.

5 an be tailored through artificial structural engineering.

6 ly attached to receptors by metabolic glycan engineering.

7 research, niche construction, and ecosystem engineering.

8 oxides and controlled by surface-termination engineering.

9 n integral for advancing the field of tissue engineering.

10 ultimately impact many fields of science and engineering.

11 nsights will guide vascular regeneration and engineering.

12 nd therefore be a powerful tool for cellular engineering.

13 g customized cell-based therapies for tissue engineering.

14 own internal models, with minimal human hand engineering.

15 the study of metabolic pathway evolution and engineering.

16 CRISPR-Cas9 systems and may facilitate Cas9 engineering.

17 s great potential for cell-based bone tissue engineering.

18 s expressed as observables through materials engineering.

19 n the fields of sensory materials and device engineering.

20 ld represent an important advance for tissue engineering.

21 diverse fields, ranging from neuroscience to engineering.

22 ons is at the heart of (applied) science and engineering.

23 iences, material sciences and high-precision engineering.

24 ization to solving problems in chemistry and engineering.

25 body domains in isolation would aid in their engineering.

26 aking them interesting targets for metabolic engineering.

27 ndamental interest in biological science and engineering.

28 ll these advantages can only be reached when engineering a complex type of material, nanocomposites,

29 f late-onset HPP with extended life spans by engineering a floxed Alpl allele, allowing for condition

30 lementation (AiFC) method for RNA imaging by engineering a green fluorescence protein (GFP)-mimicking

31 We rewrote the entire ImageJ codebase, engineering a redesigned plugin mechanism intended to fa

32 reamlined de novo DNA synthesis approach for engineering a synthetic pathway with microchip-synthesiz

33 zed that exogenous forces can be applied for engineering a variety of significantly different MSC sha

34 Tissue engineering, a recent promising way to possibly resolve

35 ools that can be used to regulate the genome engineering activities of CRISPR-Cas9.

36 r of materials is the key to fundamental and engineering advances in materials' performance.

37 Advances in stem cell biology and engineering allow for the generation of constructs that

38 t-phenotype mapping provides a framework for engineering AMPAR gating using auxiliary subunits.

39 We believe that this example of engineering an adaptive Li/electrolyte interface brings

40 However, engineering an increasingly positive charge in a critica

41 prompt a revolution in mitochondrial genome engineering and biological understanding.

42 Finally, genetic engineering and cell-specific application of extracellul

43 Based on the engineering and characterization of a minimal CPC, we su

44 Recent advances in enzyme engineering and design have expanded nature's catalytic

45 Engineering and enhancing the breaking of inversion symm

46 Engineering and evaluation of synthetic routes for gener

47 crystals, which requires careful dispersion engineering and is usually narrowband.

48 use of models in modern applications such as engineering and manipulating microbial metabolism by syn

49 roach to emerging RGENs should enhance their engineering and optimization for therapeutic and other a

50 a complex phenotype through multiplex genome engineering and predictive modeling.

51 ogels should find use in a variety of tissue engineering and regenerative medicine applications.

52 rous scaffolds play a pivotal role in tissue engineering and regenerative medicine by functioning as

53 showcase their broad applications in tissue engineering and regenerative medicine, followed by a sum

54 and are widely used biomaterials for tissue engineering and regenerative medicine.

55 h may be amenable to numerous enzymes and to engineering and screening approaches to identify activat

56 latform technology that combines recombinant engineering and site-specific conjugation to create mult

57 loped using the design principles of crystal engineering and structure-property correlations, resulti

58 pplications in different fields in medicine, engineering and technology but their enhanced mechanical

59 novel insights into the antibody alternative engineering and the universal application in biological

60 d blockers with strong, specific binding for engineering and therapeutic applications.

61 advances in bioreactor technology, metabolic engineering, and analytical instrumentation are improvin

62 in the selection of optimal T cells, genetic engineering, and cell manufacturing are poised to broade

63 n through selective breeding without genetic engineering, and fuels the topical controversy of revivi

64 , decision science, alternatives assessment, engineering, and law and policy.

65 arge numbers of college science, technology, engineering, and mathematics (STEM) faculty to include a

66 eveloping competence in science, technology, engineering, and mathematics (STEM) is critically import

67 ittee of the National Academies of Sciences, Engineering, and Medicine has made 14 recommendations th

68 various interdisciplinary areas of science, engineering, and medicine.

69 nfrared imaging, chemical sensing, materials engineering, and quantum information processing.

70 ic strategies including cell therapy, tissue engineering, and regenerative medicine and are frequentl

71 se systems have been applied in therapeutic, engineering, and research settings.

72 trategy combining anion substitution, defect engineering, and the dopant effect to address the above

73 ication of nanocomposite hydrogels in tissue engineering applications are described, with specific at

74 For engineering applications, however, the failure probabili

75 as systems have potential for many microbial engineering applications, including bacterial strain typ

76 lular urethra bioscaffolds for future tissue engineering applications, using bioscaffolds or bioscaff

77 possess several unique attributes for genome engineering applications.

78 tailored to different biomedical and tissue engineering applications.

79 , civil, materials, electronics and chemical engineering applications.

80 d evidence in the context of a human factors engineering approach as well as educational intervention

81 Herein, we demonstrate a new microstructural engineering approach for producing low-cost titanium all

82 inone monomers we now present a model-driven engineering approach to improve molecular buffering usin

83 s of gene expression dynamics with a reverse engineering approach to infer data-driven dynamic networ

84 Accordingly, we used a glyco-engineering approach wherein synthetic CD22 ligands link

85 vity and pave the way to explore new protein engineering approaches aimed at designing redox-active p

86 are distinct from commonly leveraged stealth engineering approaches such as nanoparticle surface func

87 and dicot genomes using a variety of genome engineering approaches.

88 recent advances regarding terpene metabolic engineering are highlighted, with a special focus on tob

89 Advances in biological engineering are likely to have substantial impacts on gl

90 Moreover, recent advances in antibody engineering are providing further improvements in MAb po

91 uman skin is a promising conduit for genetic engineering, as it is the largest and most accessible or

92 A century-old tenet in physics and engineering asserts that any type of system, having band

93 In tissue engineering, autofluorescence of polymer scaffolds often

94 Here we describe genome-engineering based evaluation of RNA regulatory element a

95 Here, an overview of the latest studies on engineering biomaterials for the enhancement of anticanc

96 Here, we review advances in engineering both imaging modalities and material propert

97 lowering kappaL , but also the importance of engineering both thermal and electronic transport simult

98 o engage with the public on GMOs and genetic engineering broadly.

99 as9 endonucleases are widely used for genome engineering, but our understanding of Cas9 specificity r

100 e assessed the indirect effects of ecosystem engineering by a wood-boring beetle in a neotropical man

101 By engineering C-terminal charges, we develop CRY2high and

102 Tissue-engineering can serve as an alternative to conventional

103 zed against phase separation by deliberately engineering carrier diffusion lengths and injected carri

104 and fisheries, and those in professional and engineering categories had higher relative mortality ris

105 In cardiac tissue engineering cells are seeded within porous biomaterial s

106 nd sensing to targeted genome regulation for engineering cellular functions.

107 cations, while avoiding the safety risks and engineering challenges associated with viruses.

108 s, making FTVs impractical due to instrument engineering challenges.

109 rotein design and discuss best practices for engineering chromatin to assist scientists in advancing

110 ived strong interest from the scientific and engineering communities because they offer fresh approac

111 nal (3D) architectures that bypass important engineering constraints and performance limitations set

112 ons show that the inner and outer structural engineering contributing to the synergistic effects of 2

113 ons among plumbing components that undermine engineering controls for opportunistic pathogens (OPs).

114 Improving DGAT activity using protein engineering could lead to improvements in seed oil yield

115 Recently, we have successfully achieved engineering critical current density beyond 2.0 kA/mm(2)

116 s making it a potentially useful pathway for engineering crop plants with improved drought tolerance.

117 logy, quality improvement, cognitive systems engineering (CSE), and applied cognitive psychology.

118 o improve the fuel economy of vehicles using engineering design modifications that compromise other p

119 This fundamental property is used in diverse engineering designs including mechanical, civil, materia

120 We investigated this idea by engineering di-ubiquitin chains containing differential

121 synthetic biology has been reinvented as an engineering discipline to design new organisms as well a

122 the first focus is a discussion on molecular engineering (e.g., backbone, side chains, and substituen

123 ts), then the discussion moves on to polymer engineering (e.g., molecular weight).

124 to plant growth and defense will help lignin engineering efforts to improve the production of biofuel

125 terparts, indicating that current polymerase engineering efforts would benefit from new benchmarking

126 Our work provides general guidelines for engineering electromagnetic illusions but can be extende

127 ion metal oxides, and provides a pathway for engineering emergent properties in quantum matter.

128 d may greatly accelerate future genome-scale engineering endeavours in yeast.

129 Incorporating engineering ethics early during the planning stages of o

130 cel based bottom-up model is developed using engineering first-principles to calculate mass and energ

131 ol and has formed the foundation of cellular engineering for adoptive cell therapy in cancer and othe

132 We argue that metabolic engineering for producing the secondary metabolites in p

133 DSDs have applications in metabolic engineering for the production of valuable protocatechua

134 uld be performed as a function of metal node engineering, framework topology, and/or the presence of

135 He obtained a BSc in aerospace engineering from the University of Cincinnati in 1969 an

136 rotein immobilization strategies is vital to engineering functional hydrogels.

137 Tissue engineering, gene therapy, drug screening, and emerging

138 a rich interplay of fundamental science and engineering, give rise to fascinating everyday effects (

139 ed is key to meeting these challenges and to engineering guard cells for improved water use efficienc

140 )H NMR data, demonstrating that model-driven engineering has considerable potential in supramolecular

141 Protein engineering has enabled the optimization of existing enz

142 Organoid technology and organ-on-a-chip engineering have emerged as two distinct approaches for

143 ype Spectralis OCT-A (Spectralis; Heidelberg Engineering, Heidelberg, Germany), AngioPlex (Cirrus 500

144 sing a wide-angle Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany).

145 Engineering high-energy interfacial structures for high-

146 Finally, we examine possibilities of engineering hormone cross talk for improvement of plant

147 f delivery of immunomodulatory therapeutics, engineering immune cells, and constructing immune-modula

148 t layers revealed the specificity of isotope engineering in a layered material, with a modification o

149 strategy for multiplex combinatorial genome engineering in eukaryotes.

150 d force could be external stimuli for domain engineering in ferroelectrics with significant current l

151 Genetic engineering in mice enables the time-controlled labeling

152 hieved in Escherichia coli through molecular engineering, including manipulation of the protein trans

153 Strain engineering is a promising method for next-generation ma

154 ticated devices based on 2D materials.Strain engineering is an essential tool for modifying local ele

155 Cell surface engineering is an expanding field and whilst extensive r

156 trategy involving outer and inner structural engineering is developed for superior water splitting vi

157 Tissue engineering is one of the most prominent examples of int

158 olecular assembly and hierarchical molecular engineering is to control and program the directional se

159 The goal of tissue engineering is to mitigate the critical shortage of dono

160 thods for widespread epigenome profiling and engineering may generate new avenues for using the full

161 The rapidly improving tools of genetic engineering may make it possible to overcome the humoral

162 derlying distinct cell fates using a reverse engineering method and uncovered the dose-dependent rewi

163 rent capabilities of the widely used protein engineering method, expressed protein ligation.

164 To enable iterative genome engineering, Millstone allows users to design oligonucle

165 ons of this mechanism can be created through engineering minimal antisense RNAs.

166 responsive fashion, providing a platform for engineering molecular circuits and devices with a wide r

167 In engineering MPs, it can be extremely challenging to reta

168 PR solves the major problem of animal genome engineering, namely the inefficiency of targeted DNA cas

169 Engineering nanoparticle (NP) functions at the molecular

170 egies of excessive Li and better interfacial engineering need to be investigated.

171 Here the authors develop a screen for engineering new split FPs, and report a yellow-green spl

172 gnant tissue growth, regenerating organs and engineering new-age medical devices.

173 Significant progress has been made in engineering novel aptamer domains for new small molecule

174 Rational surface engineering of 2D nanoarchitectures-based electrode mate

175 Here, we demonstrate controlled strain engineering of 2D semiconductors during synthesis by uti

176 Here we report the engineering of a cytochrome P450 enzyme by directed evol

177 Here, we describe the engineering of a light-activated human caspase-3 (Caspas

178 Here we report the engineering of a protein scaffold for preferential bindi

179 on a plant FBP appears useful for metabolic engineering of a wide range of crops to enhance the cont

180 es such chromophores are rare, and molecular engineering of absorbers having such properties has prov

181 ity in the biology of real organisms and the engineering of artificial microswimmers.

182 ory control of carotenogenesis and metabolic engineering of carotenoids in light of plastid types in

183 orating cell surfaces with biomolecules, the engineering of cell surfaces with particles has been a l

184 variants, providing a basis for the further engineering of CRISPR-Cpf1.

185 We used CRISPR/Cas9 genome engineering of Drosophila legless (lgs) and human BCL9 a

186 hape global agriculture through the targeted engineering of endogenous pathways or the introduction o

187 try breaking paves the way for deterministic engineering of fractional quantum Hall states, while our

188 ers (e.g. Sox2-V5 and Sox2-mCherry); and (4) engineering of glioma mutations (TP53 deletion; H3F3A po

189 resent a transformational approach to genome engineering of herpes simplex virus type 1 (HSV-1), whic

190 chemistry, thereby permitting the bottom-up engineering of increasingly complex reaction networks fr

191 ision breeding of plants and animals and the engineering of industrial microbes.

192 ing mathematical modelling and the molecular engineering of insulin itself and its potency, towards a

193 g as promising alternatives to the metabolic engineering of living cells.

194 of co-translational integration and for the engineering of membrane proteins with enhanced membrane

195 benzene as a versatile aromatic scaffold for engineering of molecular materials with tailored and exp

196 r coexistence is a promising route in defect engineering of MoS2 to fabricate suitable devices for el

197 The engineering of mouse models of inherited aortopathies ha

198 These results may guide the rational engineering of multilayer and core-shell oxide nanomater

199 ally "noisy" bioenvironments require careful engineering of nanoscale components that are highly sens

200 inimization and potentially accelerating the engineering of next-generation thermoelectric devices.

201 bility of using yeast to accelerate rational engineering of nonribosomal peptide antibiotics.

202 Facet engineering of oxide nanocrystals represents a powerful

203 ect extraction, recent progress in metabolic engineering of plants offers an alternative supply optio

204 synthetic biology that involve the multistep engineering of plastid genomes.

205 osts provided proof of concept for metabolic engineering of pseudolaratriene.

206 ht and matter are strongly coupled, allowing engineering of rapid changes in the force landscape, sto

207 evelop and implement strategies for in vitro engineering of replacement kidney tissue, and to devise

208 ed here provide a valuable tool to guide the engineering of specific Env glycoforms for HIV vaccine d

209 This concept of bending strain engineering of spins via topological nanomechanical arch

210 aling will allow improved strategies for the engineering of staple crops to accumulate additional bio

211 rther understanding of stem cell biology and engineering of stem cells for therapeutic applications.

212 To conclude, mRNA-based engineering of stem cells is a rapid and integration-fre

213 s exciting opportunities for molecular-level engineering of stress-responsive properties of polymers.

214 ities because they offer fresh approaches to engineering of structural hierarchy and adaptive functio

215 Genetic engineering of structure-designed bromodomain and plant

216 Many of these projects will require the engineering of substantial changes in fluxes of central

217 In the present study, complex engineering of the carotenoid pathway has been performed

218 Atomically precise engineering of the position of molecular adsorbates on s

219 essing the quality of the gates used for the engineering of their state.

220 ays, and also examine sample problems in the engineering of these pathways.

221 lications presented, a vision for the future engineering of wood-based materials to promote continuou

222 Additional surface engineering on the next generation immunogen, DEKnull-2,

223 his living component is rarely considered in engineering operations carried out in these environments

224 The insights we obtain are important for engineering opto-spintronic devices that rely on optical

225 unity or self-targeted cell killing, and the engineering or control of metabolic pathways for improve

226 chieved in the three domains without feature engineering or the use of knowledge sources.

227 Herein we utilize an engineering perspective to advance understanding of the

228 method can also be incorporated into tissue engineering platforms in which depletion of the stem cel

229 date, conservation investment has emphasized engineering practices or vegetative strategies centered

230 roperties in ceramics through grain boundary engineering, precise mechanical characterization of indi

231 study allowed the formulation of the general engineering principles for the selection of polymeric ma

232 Here, we define the engineering principles impacting biological activity, de

233 h breeding and through biotechnology and the engineering principles on which increased phytonutrient

234 These cell engineering processes need to be carefully controlled an

235 As the field of tissue engineering progresses ever-further toward realizing cli

236 ied that may be exploited for photosynthesis engineering projects in the future.

237 Neuromorphic engineering promises to have a revolutionary impact in o

238 OFs) were investigated as a model system for engineering radionuclide containing materials through ut

239 E to site saturation mutagenesis for protein engineering, reconstruction of adaptive laboratory evolu

240 of biomedical applications including tissue engineering, regenerative medicine, and cell and therape

241 as a platform for synthetic biology, strain engineering remains slow and laborious.

242 as advanced materials in biomedicine, tissue engineering, renewable energy, environmental science, na

243 nce might benefit from deeper involvement in engineering research in the area of health.

244 problem, we demonstrate that modular tissue engineering results in an s.c. vascularized bed that ena

245 es is a promising platform for future tissue-engineering scaffolds and biomedical applications.

246 Dormancy was also reduced by engineering seed-specific accumulation of jasmonic acid

247 tensively used molecular building blocks for engineering self-assembling materials.

248 rovements in plant photosynthesis by genetic engineering show considerable potential towards this goa

249 pplications such as medical implants, tissue engineering, soft robotics, and wearable electronics.

250 es of the embryonic mesenchyme and establish engineering strategies for more robustly directing tissu

251 n, which may be useful in future dentin-pulp engineering strategies that target fibroblast C5L2 to in

252 oduced from diacylglycerol (DAG), successful engineering strategies to enhance TAG levels have focuse

253 insight for future phenylpropanoid metabolic engineering strategies.

254 s with computational modelling to design the engineering strategy and to understand the metabolic phe

255 bility via a generally applicable orthogonal engineering strategy presented here.

256 Here, we demonstrate a novel dissipation engineering strategy that can support stable oscillation

257 strates the feasibility of applying a tissue engineering strategy towards the development of scalable

258 sfully developed by a simple chemical defect-engineering strategy.

259 antibody specificity as an emerging antibody engineering strategy.

260 Incoming women engineering students (n = 150) were randomly assigned to

261 Important implications of our findings for engineering synthetic circuits are: (i) sRNAs can potent

262 Engineering synthetic pathways for production of alpha-m

263 terologous expression in a modular metabolic engineering system in Escherichia coli Members of the TP

264 Engineering T cells with an Akt-insensitive Ezh2 mutant

265 ly applicable as scaffolds in cardiac tissue engineering (TE).

266 romagnetic metals by using various interface engineering techniques is presented, such as inserting a

267 Band-engineering techniques should aim to a full control of t

268 es to solve the limitations of materials and engineering techniques.

269 ization treatment offer the possibilities of engineering the advanced hybrid perovskites with specifi

270 Engineering the Bacillus paralicheniformis 9945a DISARM

271 NV protease binding affinity, as revealed by engineering the binding loop of aprotinin, a small prote

272 Our approach of engineering the conserved processes of DNA replication,

273 cks, there has been longstanding interest in engineering the incorporation of alternative extender un

274 Engineering the preform structure grants control over th

275 dipose-derived stem/stromal cells (ASCs) for engineering the pulmonary vasculature in a decellularize

276 rical rules are inherently less reliable for engineering the structures of molecular solids.

277 e material system with reduced dimension via engineering the surface boundary conditions.

278 ernative grafting-from strategy for directly engineering the surfaces of live yeast and mammalian cel

279 tes and metamaterials at bulk length-scales, engineering the thermal conductivity at micro- and nano-

280 alidation in cohorts with severe obesity and engineering the variants in model organisms will be need

281 w understanding has emerged renewed hope for engineering these assembly lines to produce new material

282 However, engineering this transformation deliberately using ion i

283 so present a possible strategy based on loss engineering to achieve more control over the mode select

284 d will facilitate CAM-into-C3 photosynthesis engineering to enhance water-use efficiency in crops.

285 properties of neuronal dynamics and in neuro-engineering to implement closed-loop applications.

286 hydroxylation in OleTJE could enable protein engineering to improve catalysis or to introduce decarbo

287 (Pik) pentaketides that mimic early pathway engineering to probe the substrate tolerance of the PikA

288 and demonstrate the feasibility of metabolic engineering to produce components of these defense compo

289 use as synthetic biology moves beyond parts engineering to the design and construction of more sophi

290 allenge of chemistry, materials science, and engineering to understand and mimic biological systems t

291 The genetic engineering tools and resources established in this stud

292 Since engineering trimers can be limited by the difficulty of

293 ermoelectric materials through crystal phase engineering using a strategy of entropy stabilization of

294 The entropy engineering using multicomponent crystal structures or o

295 molecule superresolution imaging and genetic engineering, we study in living Escherichia coli cells t

296 s in metal-free catalysis or organic crystal engineering, where double-H-bonding donor boronic acids

297 us propose new approaches of plant metabolic engineering, which are inspired by an ancient Chinese ir

298 -mismatched constituents also enables strain-engineering, which can be used to further enhance materi

299 Approaches that integrate vaccine engineering with an understanding of evolution and epide

300 validates the promising combination of plant engineering with microbial chassis development for the p