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1 transplanted subcutaneously alone failed to engraft.
2 All recipients of TN-depleted PBSCs engrafted.
3 enated rewarming (COR) for 90 minutes before engrafting.
5 e, we studied whether redirected T cells can engraft after adoptive transfer, without prior T-cell de
7 ma cell lines and patient-derived xenografts engraft and adopt a metastatic program in chick embryos.
8 f TECs, and further show that young TECs can engraft and directly drive the growth of involuted thymu
9 ized different HBV subtypes and were able to engraft and expand in immune-competent HBV transgenic mi
12 human glial progenitor cells (hGPCs) densely engraft and myelinate the hypomyelinated shiverer mouse.
15 y of its haematopoietic stem cells (HSCs) to engraft and reconstitute the blood and bone marrow of an
16 ly that self-assembled allogeneic constructs engraft and reject similar to allogeneic skin despite th
18 1 infection, these coreceptor negative cells engraft and traffic normally, and are protected from inf
19 At day 100, 35 (92%) of 38 patients were engrafted and alive in the cyclophosphamide 50 mg/kg coh
24 When injected into dystrophic mice, MiPs engrafted and repaired both skeletal and cardiac muscle,
25 The findings indicated that transplanted KC engrafted and survived in recipient livers throughout th
26 se data demonstrate that genome-edited HSPCs engraft, and contribute to multilineage repopulation aft
27 n assays, we show that HSCs emerge, migrate, engraft, and differentiate in the absence of cdh5 expres
30 l research focused on the ability of MSCs to engraft at sites of tissue injury, increasing evidence s
33 anted Nalm-6 or Molm-13 human leukemia cells engrafted at a threefold higher rate in adipocyte-rich C
35 (-)CD34(+)CD38(lo) stem cell population, and engrafted B-1 cells in humanized mice exhibit an Ig-usag
42 ve hematopoiesis and production of long-term engrafting CD34+ cells, suggesting these ligands are cri
45 l explants demonstrated proliferation of the engrafted cells and ability to generate crypt-like struc
48 ed control of graft function, and activating engrafted cells drives behavioral changes in transplante
51 o the livers, resulting in a larger bolus of engrafted cells in the host livers under quiescent condi
52 rom human embryonic stem cells and show that engrafted cells replenish depleted precursor numbers, ge
57 ation, and that this loss can be reversed by engrafting cells back into an intact CNS environment.
61 cell (BMSC) subsets with enhanced ability to engraft/contribute to the resident intestinal cellular p
63 d onto infarcted, immune tolerant rat hearts engrafted, displayed both host and graft-derived vascula
64 week post-infarct immune tolerant rat hearts engrafted, displayed evidence for host vascular coupling
65 r effect of AlloSCT is due to the ability of engrafting donor derived lymphocyte populations to eradi
70 e islet seeding, the scaffold was allowed to engraft for 28 days to allow the tissue response to damp
73 ); proT2, CD34(+)CD7(+)CD5(+)) showed thymus engrafting function, proT2-cells exhibited superior engr
75 AGM AKT-ECs specified into long-term, adult-engrafting HSCs, establishing that a vascular niche is s
76 ransgenic mice and immunodeficient mice with engrafted human CD34(+) cells that HSPCs transduced in t
77 in a NOD/SCID/IL2Rgamma(-/-) mouse model of engrafted human chronic myelogenous leukemia, we now dem
79 ecies-selective properties of human glia, we engrafted human glial progenitor cells (GPCs) into neona
80 isms underlying the remaining defects in the engrafted human immune system and are generating "next g
83 elial progenitor cell (EPC) recruitment into engrafted human synovium that was injected intragraft wi
84 eveloped mice with humanized white matter by engrafting human glial progenitor cells (GPCs) into neon
87 a greater capacity to form spheroids and to engraft immune-deficient mice than did ROR1-negative (RO
88 agocytic myeloid cells in vitro and can also engraft immunodeficient mice, generating myeloerythoid a
93 the elimination of AML stem cells capable of engrafting immunodeficient mice by chemotherapeutic agen
94 lished human HD glial chimeras by neonatally engrafting immunodeficient mice with mutant huntingtin (
95 results in their apoptosis and inability to engraft, implicating HIF-1alpha or HIF-2alpha as therape
96 characteristics and have been shown able to engraft in and repopulate both animal and human livers.
104 ouse colon organoids and human CRC organoids engraft in the distal colon and metastasize to the liver
105 Because few intravenously administered MSCs engraft in the myocardium, studies have mainly utilized
107 rogenitor cells (HSC/Ps) fail to effectively engraft in transplantation experiments, exhibiting norma
109 ntial in vitro and were the only fraction to engraft in vivo, although at low levels, following propa
110 argeting and can form nephron organoids that engraft in vivo, functionally couple to the host's circu
116 tion of human hematopoietic progenitor cells engrafted in immune deficient mice (huNSG) results in vi
122 t 7 d post-transplant, the EphB2(high) BMSCs engrafted in the ISC region at levels of 2.1 +/- 0.2%, w
123 ifferentiated from hESCs and hiPSCs could be engrafted in the liver parenchyma of immune-deficient tr
124 nted adult KC were successfully targeted and engrafted in the liver with retention of innate immune a
129 s are responsible for the production of DRs, engrafting in the recipient liver and localizing to the
131 bone marrow-derived circulating EPCs do not engraft into blood vessels, but that such circulating ce
132 d with light-inducible NPs containing RA can engraft into bone marrow in vivo in the proximity of oth
134 last ability to cross the vessel wall and to engraft into damaged myofibres through the modulation of
135 re colony-forming-cell potential and durably engraft into immune-deficient mice after primary and sec
136 freshly isolated hBTSCs were equally able to engraft into immunocompromised mice yielding cells with
138 we document that human MiPs can successfully engraft into the skeletal muscle and hearts of dystrophi
140 e show that SDF-1alpha-expressing COS1 cells engrafted into a regeneration-incompetent digit amputati
143 r inflammation was induced in human arteries engrafted into immunodeficient mice that were reconstitu
144 - and CB-iPSC-derived VPs reliably homed and engrafted into injured retinal capillaries, with incorpo
145 del of TNBC in which Eo771/MUC1-C cells were engrafted into MUC1 transgenic mice, we showed that targ
146 a mouse model in which human glial cells are engrafted into neonatal mice that are both immunodeficie
148 on channel channelrhodopsin-2, which we then engrafted into partially denervated branches of the scia
150 l of liver failure, the rat liver stem cells engrafted into the host liver where they differentiated
152 nes and tested their capacity for homing and engrafting into murine retina in an ischemia-reperfusion
153 disease phenotype to normal mice, since mice engrafted intrastriatally with mHTT hGPCs exhibit worse
154 e first hematopoietic stem cells (HSCs) that engraft irradiated adult mice arise in the aorta-gonad-m
162 ogenesis of myeloproliferative neoplasms, we engrafted lethally irradiated recipient mice with bone m
163 now demonstrate the complete elimination of engrafted leukemia after only one course of combined che
169 However, glycoengineered hiPS-HSPCs did not engraft long-term, indicating that additional functional
171 nted onto rat hearts, cardiopatches robustly engraft, maintain pre-implantation electrical function,
172 s, the ability for the tumor of a patient to engraft may help identify those patients who will benefi
173 types of genetically MC-deficient mice after engrafting MCs that either do or do not express TNFRSF14
174 rgen-specific gut inflammation in human PBMC-engrafted mice can be avoided by enhancing the numbers o
175 and improves the survival of orthotopically engrafted mice implanted with human PTEN-deficient gliom
181 early 2000s, investigators have been able to engraft murine recipients with human hematopoietic stem
182 In this study we developed a human PBMC-engrafted murine model of allergen-driven gut inflammati
186 aematopoietic stem and progenitor cells that engraft myeloid, B and T cells in primary and secondary
187 onic HSCs from E9.5 and E10.5 preferentially engrafted neonates, whereas developmentally mature, defi
189 READD-dependent stimulation or inhibition of engrafted neurons, revealing D1 receptor-dependent regul
192 Modified cells maintained their ability to engraft NOD/SCID/IL2rgamma(null) mice and to produce cel
195 uppressive M2-like phenotype in vitro and in engrafted nonobese diabetic-severe combined immunodefici
196 the survival, maturation, and integration of engrafted NSC/NPCs as a restorative treatment for PD.
197 3A-APC-potentiated neuronal recruitment from engrafted NSCs might offer a new approach to the treatme
198 Here, using human haematopoietic stem cell-engrafted NSG-HLA-DQ8 transgenic mice, we provide direct
200 or prognostic AMLs or for samples capable of engrafting NSG mice compared with good risk AMLs or none
202 nced the activity of anti-ErbB2 mAb to treat engrafted or spontaneous tumors as well as lung metastas
206 hemoglobin and resolution of hemolysis among engrafted patients were accompanied by stabilization in
211 -) cells give rise to all blood lineages and engraft primary and secondary immunodeficient mice.
212 vation, of human myelolymphoid HSPCs able to engraft primary and secondary immunodeficient mice.
213 establish persistent replication in vivo, we engrafted primary rhesus macaque hepatocytes into immuno
216 omy (PH), transplanted stem/progenitor cells engrafted, proliferated competitively compared to host h
217 t intravenously injected rhC7 distributed to engrafted RDEB skin, incorporated into its dermal-epider
220 emarkably, when transplanted onto nude mice, engrafted SRF-null skin lacked hair but displayed normal
221 In addition, we will discuss the safety of engrafted stem cell-derived OPCs, as well as approaches
223 was no predictable relationship between the engrafting subclone and the evolutionary hierarchy of th
224 R-deficient PDAC cells lacked the ability to engraft successfully in immunocompromised mice, but IDH1
229 ost-transplantation showed 2 of the 6 clones engrafting the intestine at 4- to 5-fold higher levels (
238 lungs of human CD34+ hematopoietic stem cell engrafted virus-infected NOD.Cg-Prkdc(scid) Il2rg(tm1Wjl
240 large cohort of patient samples successfully engrafted, which covered all of the important genetic an
241 fibers were observed, showing the fusion of engrafted wild-type myoblasts with muscle fibers; on the
242 prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable t
244 blished an S. aureus infection model in mice engrafted with a human immune system, compared it with i
245 seventeen patients with MPS-IH successfully engrafted with a median follow-up age of 9.2 years were
246 ist of a tumor antigen-specific Fab molecule engrafted with a peptide neo-epitope, which is bound exc
249 a decrease in growth kinetics, whereas mice engrafted with Bim knockout tumors showed no reduction i
250 Hypercholesterolemia-prone mice that were engrafted with bone marrow obtained from homozygous or h
251 was significantly improved if the mice were engrafted with bone marrow-derived cultured mast cells f
253 progression was significantly slowed in mice engrafted with CD34(+)/CD19(-) or CD34(+)/CD7(-) and CD3
255 , we show that humanized mice, i.e., animals engrafted with components of a human immune system, that
261 ia burden and increased the survival of mice engrafted with human AML without inducing overt toxicity
263 ntration of 1 mg/kg to immune-deficient mice engrafted with human CLL cells resulted in complete clea
265 e lymphomas when directly injected into mice engrafted with human fetal CD34+ cells and human thymus.
266 type EBOV (Makona variant) infection of mice engrafted with human hematopoietic CD34(+) stem cells (H
267 e current study, we inoculated NSG-SGM3 mice engrafted with human hematopoietic CD34+ stem cells with
272 rg(-/-)Sirpa(NOD)Alb-uPA(tg/tg) mice, stably engrafted with human hepatocytes (HUHEP) with or without
273 n hepatocytes in vitro and to humanized mice engrafted with human hepatocytes in vivo but completely
276 retransplantation into immunodeficient hosts engrafted with human T cells, panel-reactive antibody--t
277 ull)SCF/GM-CSF/IL3 (NSG-SGM3) strain of mice engrafted with human thymus, liver, and hematopoietic st
280 olitinib or PU-H71 improved survival of mice engrafted with JAK2V617F-mutant, Tp53-deficient AML, dem
281 Aspergillus fumigatus when mice were heavily engrafted with leukemia cells, had severe chemotherapy-i
282 loss of skeletal muscle mass induced in mice engrafted with Lewis lung carcinoma (LLC) cells or in Ap
283 1-Kit(W/W-v) or C57BL/6J-Kit(W-sh/W-sh) mice engrafted with mast cells that did or did not express VD
284 rdingly, when infused in NSG mice previously engrafted with myeloma, SE cells mediated tumor rejectio
285 ogeneic PBMC and were more severe in animals engrafted with PBMC depleted of CD4(+)CD25(high) cells.
286 ficient NOD/SCID/IL-2Rgamma(null) (NSG) mice engrafted with peripheral blood cells from patients with
288 n vitro and in an orthotopic xenograft model engrafted with primary ALL; in the latter, reduced RAS-m
294 moniae-infected SP-A(-/-)Kit(W-sh/W-sh) mice engrafted with TNF-alpha(-/-) or TNF-R(-/-) MCs have dec
295 unodeficiency/interleukin 2Rgamma(null) mice engrafted with transformed human CD34+ hematopoietic ste
296 s production compared with that seen in mice engrafted with wild-type MCs, whereas burden was unaffec
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