ライフサイエンスコーパス: enhancer of zeste homolog 2

1 ll as the polycomb complex protein Bmi-1 and enhancer of zeste homolog 2.

2 Previous work has demonstrated that Ezh2 (enhancer of zeste homolog 2), a histone 3 lysine 27 (H3K

3 itors or depletion of the polycomb repressor enhancer of zeste homolog 2 altered relative RKIP and BA

4 stone H3 lysine 27 (H3K27) methyltransferase enhancer of zeste homolog 2 and the WD-repeat protein em

5 lso sequesters a core subunit of PRC2 (Ezh2 [enhancer of zeste homolog 2]) at the cell membrane, prev

6 sion include histone methyltransferase EZH2 (enhancer of zeste homolog 2), COX2 (cyclooxygenase-2), P

7 for multiple myeloma (MM) cell lines induce enhancer of zeste homolog 2 (ezh 2) transcript expressio

8 ) (a subunit required for PRC2 function) and enhancer of zeste homolog 2 (EZH2) (a histone methyltran

9 ating mutations in histone methyltransferase enhancer of zeste homolog 2 (EZH2) also have been observ

10 2), additional sex combs like 1 (ASXL1), PcG enhancer of zeste homolog 2 (EZH2) and DNA methyltransfe

11 ned expression of the Polycomb group protein Enhancer of Zeste Homolog 2 (EZH2) and increased tumor-i

12 ed by the polycomb histone methyltransferase enhancer of zeste homolog 2 (Ezh2) and its trimethylatio

13 Enhancer of zeste homolog 2 (EZH2) and related EZH1 cont

14 DR5 expression via the epigenetic regulator enhancer of zeste homolog 2 (EZH2) and that EZH2 control

15 enewal, with the chromatin-modifying protein Enhancer of zeste homolog 2 (EZH2) emerging as a central

16 Enhancer of zeste homolog 2 (EZH2) has been characterize

17 tion of the histone methyltransferase enzyme enhancer of zeste homolog 2 (EZH2) in attenuating oxidat

18 The role of enhancer of zeste homolog 2 (EZH2) in cancer is complex

19 s catalyzed by the histone methyltransferase enhancer of zeste homolog 2 (EZH2) in the polycomb repre

20 A new enhancer of zeste homolog 2 (EZH2) inhibitor series comp

21 with short hairpin RNA or pharmacologic PRC2/enhancer of zeste homolog 2 (EZH2) inhibitors promoted m

22 Enhancer of zeste homolog 2 (EZH2) is a critical compone

23 Enhancer of zeste homolog 2 (EZH2) is a histone methyltr

24 Enhancer of zeste homolog 2 (EZH2) is a mammalian histon

25 Enhancer of Zeste homolog 2 (EZH2) is a methyltransferas

26 The histone methyltransferase Enhancer of Zeste Homolog 2 (EZH2) is frequently dysregu

27 The histone H3 lysine 27 methyltransferase enhancer of zeste homolog 2 (EZH2) is highly expressed i

28 n profiling, that the polycomb group protein enhancer of zeste homolog 2 (EZH2) is overexpressed in h

29 Although the polycomb group protein Enhancer of Zeste Homolog 2 (EZH2) is well recognized fo

30 H3 lysine 27 (H3K27) tri-methylating enzyme, enhancer of zeste homolog 2 (EZH2) mediates epigenetic s

31 Age-dependent loss of enhancer of zeste homolog 2 (EZH2) prevents adult beta c

32 , poly (ADP-ribose) polymerase 1 (PARP1), or enhancer of zeste homolog 2 (EZH2) suppressed cell growt

33 independent interaction with E2F1 to recruit enhancer of zeste homolog 2 (EZH2) to diverse repeat seq

34 m for recruiting the H3K27 methyltransferase enhancer of zeste homolog 2 (EZH2) to PR3 and MPO loci m

35 We further demonstrated that enhancer of zeste homolog 2 (EZH2) was a target gene of

36 The PcG protein Enhancer of Zeste Homolog 2 (EZH2) works as a catalytic

37 Purpose Enhancer of zeste homolog 2 (EZH2), a chromatin remodele

38 Furthermore, Meg3 relied on functional enhancer of zeste homolog 2 (EZH2), a component of polyc

39 Enhancer of zeste homolog 2 (EZH2), a core catalytic com

40 Increased levels of enhancer of zeste homolog 2 (EZH2), a critical regulator

41 mediated repression of rap1GAP that involves Enhancer of Zeste Homolog 2 (EZH2), a histone methyltran

42 Here we show that Enhancer of zeste homolog 2 (Ezh2), a histone methyltran

43 Enhancer of zeste homolog 2 (Ezh2), a member of this lar

44 Enhancer of Zeste homolog 2 (EZH2), a methyltransferase

45 Enhancer of zeste homolog 2 (EZH2), a subunit of Polycom

46 tes a physical interaction between Snail and enhancer of zeste homolog 2 (EZH2), an enzymatic subunit

47 Here, we show enhancer of zeste homolog 2 (EZH2), an enzyme that catal

48 Here we report that enhancer of zeste homolog 2 (EZH2), the catalytic subuni

49 Enhancer of Zeste Homolog 2 (EZH2), the lysine methyltra

50 A mammalian PcG protein, enhancer of zeste homolog 2 (Ezh2), triggers transcripti

51 cy of enhancer of zeste homolog 1 (Ezh1) and enhancer of zeste homolog 2 (Ezh2), which encode the enz

52 Enhancer of zeste homolog 2 (EZH2), which encodes the hi

53 The Polycomb group protein enhancer of zeste homolog 2 (EZH2), which has roles duri

54 opment, and coincides with redistribution of enhancer of zeste homolog 2 (EZH2)-dependent histone H3

55 infection bypassed AR signaling by promoting enhancer of zeste homolog 2 (EZH2)-mediated epigenetic s

56 that down-regulation of miR-34a is caused by Enhancer of zeste homolog 2 (EZH2)-mediated H3 lysine 27

57 This study explored the role of G9a- and enhancer of zeste homolog 2 (EZH2)-mediated methylation

58 s, catalyzed by the histone-modifying enzyme enhancer of zeste homolog 2 (EZH2).

59 genetic repressor, histone methyltransferase enhancer of zeste homolog 2 (EZH2).

60 The enhancer of zeste homolog-2 (EZH2) represses gene transc

61 ransferase-2 (G9a), histone deacetylases and enhancer of zeste homolog-2 (EZH2), but only G9a inhibit

62 to the promoter region of NEDD4L and recruit enhancer of zeste homolog 2 histone methyltransferase to

63 tin protein 1, methyl-CpG binding protein 2, Enhancer of Zeste homolog 2, histone deacetylase 1, and

64 EZH2 (enhancer of zeste homolog 2) is a critical enzymatic sub

65 ablish that the polycomb group protein EZH2 (enhancer of zeste homolog 2) is down-regulated during os

66 Histone methyl transferase EZH2 (Enhancer of Zeste Homolog 2) is generally associated wit

67 terized by recruitment of the polycomb group enhancer of zeste homolog 2 methyltransferase and the ac

68 hylation of H3 lysine 9 and interaction with enhancer of zeste homolog 2, the catalytic subunit of po