ライフサイエンスコーパス: enhancer sequence

1 a transcriptionally active site in a BNIP3L enhancer sequence.

2 cts were assayed with a probe containing the enhancer sequence.

3 of multiple nuclear factors with the PTTG 5' enhancer sequence.

4 sfection experiments, we delineated the core enhancer sequence.

5 icing, indicating the presence of a splicing enhancer sequence.

6 associates with a cis-acting recombinational enhancer sequence.

7 ilar to that found in an embryonic stem cell enhancer sequence.

8 t between the silver nanocluster and the DNA enhancer sequence.

9 event PU.1-mediated IRF-4 recruitment to the enhancer sequence.

10 count for the evolutionary invariance of the enhancer sequence.

11 nt of RNA polymerase II complex to the BCAS3 enhancer sequence.

12 operty also constrains this highly conserved enhancer sequence.

13 gene has a hematopoietic-specific functional enhancer sequence.

14 activates splicing through intronic splicing enhancer sequences.

15 nal differences in the mouse and human renin enhancer sequences.

16 rs showed distinct preferences for different enhancer sequences.

17 rus but had acquired various duplications of enhancer sequences.

18 t contain either insulin or albumin promoter/enhancer sequences.

19 splicing from a number of intronic splicing enhancer sequences.

20 which function through binding to the E-box enhancer sequences.

21 l lines and contains negative regulatory and enhancer sequences.

22 ting a position dependence of the U3-encoded enhancer sequences.

23 and DNA recombination via Pax5 and distal 3' enhancer sequences.

24 transcription factor protein binding at the enhancer sequences.

25 issue, suggesting nucleotide polymorphism in enhancer sequences.

26 d CNS depends on both its 5' promoter and 3' enhancer sequences.

27 transgenic mice, using Col2a1 gene promoter/enhancer sequences.

28 identical proximal promoter and far upstream enhancer sequences.

29 cyclic AMP response element (CRE) family of enhancer sequences.

30 at preceded stable association of Prmt5 with enhancer sequences.

31 expression was driven by mouse Pax3 promoter/enhancer sequences.

32 ontaining the promoter and dioxin-responsive enhancer sequences.

33 es that integrate input from multiple distal enhancer sequences.

34 loop between the PPARgamma2 promoter and an enhancer sequence 10 kb upstream that forms at the onset

35 We describe a translation enhancer sequence (3'TE) located in the 3'-untranslated

36 the PB response activity to a 290-bp distal enhancer sequence (-3483/-3194) of the UGT1A1 gene.

37 and reporter gene constructs, a 200 bp Grm6 enhancer sequence, a 445 bp Cabp5 promoter sequence, and

38 RNA recognition motif to an exonic splicing enhancer sequence, a phenomenon reversed by SRPK1 phosph

39 The associated SNPs localized to enhancer sequences active in thymus, T and B cells, and

40 ated aryl hydrocarbon receptor to the CYP1A1 enhancer sequence; additionally, NO-aspirin 2 suppressed

41 phenotypes, caused by insertion of the viral enhancer sequences adjacent to an MYB transcription fact

42 f inoculation and the presence of the PyF101 enhancer sequences affected the patterns of MCF generati

43 tion of viral mRNAs containing a translation enhancer sequence also contributes to the disassembly of

44 Consequently, divergence in enhancer sequence and activity is thought to be an impor

45 By inserting a PEG linker between an enhancer sequence and alternative splice sites, the inte

46 ted dinucleosome templates using the albumin enhancer sequence and found that site-specific binding o

47 Pak1 associated with the upstream enhancer sequence and promoter of PFK-M and was involved

48 animal regulatory genome and the make-up of enhancer sequences and confirms and generalizes principl

49 Second, SR proteins bind to exonic enhancer sequences and recruit spliceosome components to

50 intrachromosomal interaction between remote enhancer sequences and the proximal promoter region thro

51 c-Fos and c-Jun bound the cyclin D1 -954 enhancer sequence, and the abundance of c-Fos within thi

52 programmed to take place at tissue-specific enhancer sequences, and our data show that the methylati

53 re evident and include a GATA motif, octamer enhancer sequences, AP-2-like sites, and Sp1 sites.

54 Both enhancer sequences appear to have equivalent activity in

55 phenocopying the effect obtained when these enhancer sequences are deleted.

56 selective pressures exerted on the EIAV LTR enhancer sequences are different from those exerted on t

57 mink cell focus-inducing (MCF) virus, the U3 enhancer sequences are tandemly repeated in the LTR.

58 viral genome, however, proximally positioned enhancer sequences are unable to confer significant leve

59 In addition, mutation of a potential enhancer sequence, around -120, led to an 80% reduction

60 eosome positioning properties of the central enhancer sequence assembled into mononucleosome core par

61 vity 4-fold, via the AT1 receptor through an enhancer sequence at -954 base pairs.

62 NA that carries cauliflower mosaic virus 35S enhancer sequences at its right border.

63 wed that E10 splicing involved exon splicing enhancer sequences at the 5' and 3' ends of E10, an exon

64 dent of the activity of known cis-regulatory enhancer sequences at the achaete-scute complex that med

65 to-expression modeling, which interprets the enhancer sequence based on transcription factor concentr

66 and internal deletion constructs shows that enhancer sequences between nucleotides 275 and 329 are i

67 We show here that deletion of these enhancer sequences by homologous recombination is insuff

68 hancers indicates that subtle differences in enhancer sequence can have profound effects on the splic

69 ly, we show that snake and mouse orthologous enhancer sequences can display distinct expression speci

70 subsequent to the addition of the Fis-bound enhancer sequence, catalytic activity was no longer affe

71 omoter and at least one conserved noncoding (enhancer) sequence, CNS-5.

72 A bipartite enhancer sequence (composed of the O1 and O2 operator si

73 ons of zebrafish hoxb3a/hoxb4a promoters and enhancer sequences containing regions of homology that w

74 P3 robustly bind human, but not mouse, GPR15 enhancer sequences, correlating with receptor expression

75 ch included mutants with deletions of exonic enhancer sequences, did not accumulate splicing intermed

76 Our results show that separable enhancer sequences direct D-mef2 gene expression in the

77 and identified approximately 6,200 candidate enhancer sequences directly from fetal and adult human h

78 However, the complete enhancer sequence directs beta-galactosidase expression

79 We demonstrate that the wealth of new enhancer sequences discerned here provides an invaluable

80 ng human chromosome-21, implicating promoter/enhancer sequence divergence as a factor, including huma

81 We have identified a 30bp ESX enhancer sequence (EES) approximately 3 kb upstream of t

82 of a previously unidentified AAV integration enhancer sequence element which functions in cis to an A

83 IL-1beta gene, while deletion of the kappaB enhancer sequences eliminated BK-stimulated CAT activity

84 -matrix analysis to identify putative exonic enhancer sequences (ESEs), we found multiple high score

85 Reporter constructs containing stretch enhancer sequences exhibited tissue-specific activity in

86 rovirus vector containing deletions in viral enhancer sequences expressing gammac (SIN-gammac).

87 ing sites are not critical components of the enhancer sequence for PTTG trancriptional activation in

88 s in higher eukaryotes often require distant enhancer sequences for high-level expression.

89 members, predominantly c-Rel, interact with enhancer sequences for STAT5, a key transcription factor

90 oxidant response element (ARE), a cis-acting enhancer sequence found in the promoter region of many g

91 ynaptic activity response element (SARE), an enhancer sequence found upstream of many plasticity-rela

92 Ocs elements are enhancer sequences found in some pathogen and GST promot

93 binding was not affected by PRDIV, an ATF-2 enhancer sequence from the same gene.

94 nambiguously identified three new long-range enhancer sequences functionally in the Nkx2-5 gene in tr

95 TGF-beta and TNF-alpha response elements as enhancer sequences, functioning in the context of a hete

96 GATA enhancer sequences govern DKF-2 expression in intestine

97 This enhancer sequence has a high level of sequence homology

98 Both the epsilony-CACCC site at -114 bp and enhancer sequences (hypersensitive site 2 [HS2]) from th

99 ngs are consistent with the possibility that enhancer sequence hypervariability can alter expression

100 hermodynamics-based models that interpret an enhancer sequence in a given cellular context specified

101 Here we examine the LCT enhancer sequence in a large lactose-tolerance-tested Et

102 demonstrated in vivo binding of NR5A2 to the enhancer sequence in human hepatocytes.

103 over, LMX1B binds specifically to a putative enhancer sequence in intron 1 of both mouse and human CO

104 Identification of this second functional enhancer sequence in the 5'-promoter region of cathepsin

105 obarbital (PB)-responsive 132-base pair (bp) enhancer sequence in the CYP2B10 gene, we have delimited

106 ified as a ternary complex that bound to the enhancer sequence in vitro.

107 osine hydroxylase (TH) gene is controlled by enhancer sequences in its 5' flanking region; these enha

108 by inclusion of cauliflower mosaic virus 35S enhancer sequences in its promoter.

109 Both Enhancer and Weak Enhancer sequences in K562 cells were more active than n

110 NF-E2, a transcription factor which binds to enhancer sequences in the LCR.

111 The enhancer sequences in the Moloney murine leukemia virus

112 a profile of protein occupancy in the HTLV-1 enhancer sequences in the presence of high (MT-2) and lo

113 conformations required for interaction with enhancer sequences in the proximal promoter region of th

114 s family of transcription factors within the enhancer sequences in the viral long terminal repeats (L

115 iling, in vivo characterization of candidate enhancer sequences in transgenic mice, and targeted dele

116 are transcriptionally active at defined DNA enhancer sequences in vivo.

117 The SNPs are located in an 'enhancer' sequence in an intron of a neighboring gene (M

118 How distal transcriptional enhancer sequences interact with proximal promoters is p

119 e SL3 LTR were tested by inserting the viral enhancer sequences into a plasmid containing the promote

120 ing PCR-amplified, PCR-mutated, or synthetic enhancer sequences into the Ganesh family of P element r

121 Within the enhancer sequence is a 5' splice site sequence immediate

122 The enhancer sequence is conserved in the human Igkappa gene

123 The enhancer sequence is conserved within the human populati

124 forming to this motif, a typical purine-rich enhancer sequence is dispensable for either enhancer act

125 deletion within element C of the Hoxc8 early enhancer sequence is observed in baleen whales.

126 If a 35S enhancer sequence is placed next to Tag1, vegetative exc

127 DNA methylation in the distal enhancer sequence is significantly reduced, which invers

128 In this study the DF3/MUC1 promoter/enhancer sequence is used to regulate expression of gamm

129 In addition, a potent splicing enhancer sequence isolated in the selection specifically

130 Furthermore, the entire HRC enhancer sequence lacks any discernible CArG motifs, the

131 ed for islet-restricted expression: a distal enhancer sequence located between -3 and -6.5 kilobases

132 Inclusion of exon 4 requires an enhancer sequence located within the intron downstream o

133 ivators of sigma54-holoenzyme generally bind enhancer sequences located >70 bp upstream of the promot

134 cularly robust and was refined to a discrete enhancer sequence lying between nt -2832 and -2462 from

135 cleotides in length including novel splicing enhancer sequence motifs.

136 egion of this gene identified two functional enhancer sequences; namely an Sp1(N)23estrogen-responsiv

137 Mutagenesis of the enhancer sequence of the glnAp2 promoter produced varian

138 NGF expression is controlled by promoter and enhancer sequences of a keratin gene, thus restricting t

139 ers are cis linked to homologous-region (hr) enhancer sequences of AcMNPV.

140 The LTR enhancer sequences of FeLV contain identical binding sit

141 ment has become subject to regulation by eye enhancer sequences of the eya gene, disrupting normal ex

142 W to test the hypothesis that the duplicated enhancer sequences of this virus have a sequence-specifi

143 itutions were introduced into the chimpanzee enhancer sequence or reverted in the human enhancer to t

144 undertaking detailed mutational analyses of enhancer sequences, or those who wish to avoid the diffi

145 ruses is dependent on the duplication of the enhancer sequences present in the unique 3' (U3) region

146 enzymes and antioxidant proteins through an enhancer sequence referred to as the antioxidant-respons

147 an identified Mef2 enhancer, and we identify enhancer sequences required for up-regulation.

148 ft assays confirm that PAX-FKHR bind to core enhancer sequences showing similarity to consensus PAX3/

149 Deletion of the kappaB enhancer sequence significantly reduced BK-induced chlor

150 ed immunoglobulin mu gene is dependent on an enhancer sequence situated within one of the introns of

151 sembles onto the most conserved core of this enhancer sequence specifically in neuronal WERI-1 cell e

152 agents thus far tested is mediated by two 5'-enhancer sequences, SX2 and AB1, but neither fragment wa

153 ate that ESS1 is juxtaposed to a purine-rich enhancer sequence that activates the use of the 5'ss of

154 oxidant response element (ARE), a cis-acting enhancer sequence that binds Nrf2.

155 he SF2/ASF protein to a purine-rich splicing enhancer sequence that is located in the 3' exon of M1 m

156 tions in retinal explants mapped an intronic enhancer sequence that mediated NRL-directed Reep6.1 exp

157 proximal sequences and not on the cis-acting enhancer sequences that bind the aryl hydrocarbon recept

158 The Smad7 promoter contains functional enhancer sequences that bind transcription factors SMAD3

159 ticularly beneficial in the analysis of exon enhancer sequences that function in exon recognition dur

160 udies reported here, we show that additional enhancer sequences that lie outside of the core region a

161 ory specificity of predicted exonic splicing enhancer sequences that may control splicing regulation.

162 about the genomic context of this gene or of enhancer sequences that may direct its diverse functions

163 dentification and characterization of the 3' enhancer sequences that play important roles in this syn

164 t anneal to the exon and contain a 'tail' of enhancer sequences that recruit activating proteins.

165 ified ornithine decarboxylase (ODC) promoter/enhancer sequences that up-regulate target protein expre

166 Lens nuclear proteins bind the enhancer sequences to form several specific complexes, s

167 he intron, and movement of putative intronic enhancer sequences to multiple promoter-proximal sites a

168 ining Myb-binding elements in their promoter/enhancer sequences, to determine whether the phenotypic

169 LAT exon 1 (containing LAT enhancer sequences), together with the LAT promoter regi

170 in craniofacial development and suggest that enhancer sequence variation contributes to the diversity

171 Finally, the 115-bp enhancer sequence was shown to be able to activate trans

172 rter construct containing IL-1 beta promoter/enhancer sequences was introduced into MM6.

173 In the second virus, only one copy of the enhancer sequences was present.

174 to - 105, encompassing two identical 8-bp DR enhancer sequences, was necessary for CROC-1-mediated tr

175 usage in the clone 9-60 LCL, in which the W enhancer sequences were deleted upstream of Wp1, reveale

176 Cabp5 promoter sequence, and a 164 bp Chx10 enhancer sequence, were defined, each driving reporter e

177 Tf1 integration, suggesting a synergy of Tf1 enhancer sequence with the stress response elements of t

178 anscription of reporter genes containing EPO enhancer sequences with intact, but not mutant, HIF-1 bi

179 d by the interaction of Nkx6.1 with a 139 bp enhancer sequence within CR2.

180 We have identified an enhancer sequence within the PTP1B promoter which serves

181 We have also identified a G-rich intronic enhancer sequence within the small intron that is essent

182 Enhancer sequences within a 40 kb upstream fragment dire

183 Transcriptional enhancer sequences within the long terminal repeats (LTR

184 Transcriptional enhancer sequences within the long terminal repeats (LTR