ライフサイエンスコーパス: enteric

1 Combined enteric and manure methane emissions from livestock in T

2 Enteric and other bacteria use subcellular organelles kn

3 tem could include autonomic, neuroendocrine, enteric, and immune systems, with pathology resulting in

4 b2 and Edn3 (double mutants) had more severe enteric anomalies and increased neuronal differentiation

5 plastic neurological autoimmunity (including enteric/autonomic) usually related to small-cell lung ca

6 Multi-drug resistant (MDR) enteric bacteria are of increasing global concern.

7 MarR and MarA confer multidrug resistance in enteric bacteria by modulating efflux pump and porin exp

8 Enteric bacteria circumvent the gastric acid barrier by

9 e of Escherichia coli, as well as many other enteric bacteria, and are involved in cell colonization

10 n is associated with dramatic alterations in enteric bacteria, but little is known about other microb

11 romosomally encoded antibiotic resistance in enteric bacteria.

12 reside within a core regulon, shared by most enteric bacteria.

13 nrf operon promoter from various pathogenic enteric bacteria.

14 probably of other physiological processes in enteric bacteria.

15 ipenem, which has broad-spectrum coverage of enteric bacteria.

16 mance characteristics of the BD Max extended enteric bacterial panel (xEBP) assay directly from unpre

17 Campylobacter jejuni is a helix-shaped enteric bacterial pathogen and a common cause of gastroe

18 entral to macrophage function in response to enteric bacterial pathogens and is a potential therapeut

19 Enteric bacterial pathogens have developed strategies to

20 r predominantly in regions where exposure to enteric bacterial pathogens is also common.

21 HEC) and enteropathogenic E. coli (EPEC) are enteric bacterial pathogens of worldwide importance.

22 1 versus coliphage T4 in suppressing a model enteric bacterium (E. coli K-12) in mixtures with soil b

23 reading have been previously observed in the enteric bacterium Escherichia coli, and recent work in o

24 or vaccines for these viruses or the related enteric bocaviruses.

25 Enteric caliciviruses in the genera Norovirus and Sapovi

26 d handlers and fishmongers were screened for enteric carriage of GBS.

27 e performance of extant models in predicting enteric CH4 emissions from dairy cows in North America (

28 nt models were challenged on 55, 105, and 52 enteric CH4 measurements (g per lactating cow per day) f

29 current progress in techniques for measuring enteric CH4, the context in which these technologies are

30 lipid-based aspirin), and a delayed-release enteric-coated (EC) aspirin.

31 (Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated and Immediate Release Aspirin in Diabetic

32 ity to absorb cyclosporin, tacrolimus (Tac), enteric-coated mycophenolate sodium (EC-MPS) and sirolim

33 Our study reveals a high level of enteric coinfections with diverse viruses in a captive r

34 e, length, ramifications, abscess formation, enteric communication, external cutaneous opening, enhan

35 3 (OC43; an agent of the common cold), human enteric coronavirus (HECoV), equine coronavirus (ECoV),

36 eloped countries and is the leading cause of enteric disease in Australia.

37 Johne's disease (JD) is a chronic enteric disease in cattle caused by Mycobacterium avian

38 It is one of the leading causes of enteric disease in many developed countries and is the l

39 mic wasting syndrome (PMWS), respiratory and enteric disease, reproductive failure, and porcine derma

40 consideration for prevention and therapy of enteric disease.

41 cluded in piglets' feed reduces incidence of enteric disease.

42 of antibody assays for the diagnosis of PEDV enteric disease.

43 f human intestinal enteroids in the study of enteric diseases.

44 sion in complex discussions of environmental enteric dysfunction (EED) that severely affects children

45 eability and may be markers of environmental enteric dysfunction (EED), which is a condition associat

46 inadequate dietary intake and environmental enteric dysfunction (EED).We tested the hypothesis that

47 Our findings suggest that environmental enteric dysfunction is characterized by alterations in i

48 helminth infection, trachoma, environmental enteric dysfunction, and growth faltering.

49 An exposome perspective on environmental enteric dysfunction.

50 extirpation of megaherbivores reduced global enteric emissions between 2.2-69.6 Tg CH4 y(-1) during t

51 Conditional deletion of IL-17R in the enteric epithelium demonstrated that there was a recipro

52 ethane emissions, produced as a byproduct of enteric fermentation by herbivores.

53 for the rapid and culture-free diagnosis of enteric fever and non-typhoidal Salmonella bacteremia.

54 the guidelines and training for treatment of enteric fever cases in Africa are sorely needed to help

55 During 2008-2012, 2341 enteric fever cases were reported, 80% typhoid and 20% p

56 hildren bear a substantial proportion of the enteric fever disease burden in endemic areas.

57 mples from 5 patients with culture-confirmed enteric fever from Bangladesh in comparison to 3 healthy

58 es should no longer be used for treatment of enteric fever in Nepal.

59 are the relative proportion of children with enteric fever in the age groups <5 years, 5-9 years, and

60 Enteric fever in the United States is primarily associat

61 equired given the large numbers of suspected enteric fever patients with a negative culture.

62 Individual data from 2092 patients with enteric fever randomized into 4 trials in Kathmandu, Nep

63 The clinical features of enteric fever reviewed here differ between younger and o

64 g the utility of these alternative drugs for enteric fever treatment.

65 Enteric fever, caused by Salmonella enterica serovar Typ

66 Enteric fever, caused by Salmonella Typhi and Salmonella

67 the only routinely used control measures for enteric fever, the assessment of novel diagnostics, new

68 proportion of patients with culture-negative enteric fever.

69 e optimal assay for diagnosing patients with enteric fever.

70 th Asia still recommend fluoroquinolones for enteric fever.

71 tect amplified target cDNA in all 5 cases of enteric fever; no detectable signal was seen in the heal

72 Enteric foodborne pathogens, such as enterohemorrhagic E

73 Thus, commensal enteric fungi safeguard local and systemic immunity by p

74 The presence of dysfunctional CFTRs in enteric ganglia could, to a certain extent, explain the

75 The extensive expression of CFTR in the enteric ganglia suggests that CFTR may play a role in th

76 embryonic parasympathetic ganglia, including enteric ganglia.

77 These findings imply that enteric glia activation is a significant modulator of mo

78 Enteric glia also interact with various non-neuronal cel

79 We show that enteric glia and all enteric neuronal subtypes appear to

80 Here we present a current view of the enteric glia and their regulatory roles in gastrointesti

81 - and PLP1-expressing cells, which represent enteric glia and/or neural progenitors.

82 tively eliminate glia in mice, we found that enteric glia are not required for maintenance of the int

83 Contrary to widespread notions, enteric glia are therefore not required for epithelial h

84 enance of the intestinal epithelium requires enteric glia can be attributed to non-glial toxicity in

85 43) expression and enhanced ATP release from enteric glia cells.

86 In contrast, virtually all enteric glia express proteolipid protein 1 (PLP1).

87 PLP1-expressing cells selectively eliminated enteric glia from the small and large intestines, but ca

88 much remains unknown about the functions of enteric glia in health and disease.

89 In this study, we examined the role of enteric glia in mediating this secondary inflammatory re

90 Connexin-purinergic signaling in enteric glia mediates the prolonged effect of morphine o

91 mice to modify glial activity and found that enteric glia significantly contribute to the neurogenic

92 eptor activity was significantly enhanced in enteric glia that were isolated from mice with long-term

93 For instance, enteric glia, a collection of glial cells residing withi

94 enic animal models to modify the activity of enteric glia, either reducing glial expression of connex

95 Many enteric glia, however, particularly in the mucosa, do no

96 ression of P2X4, P2X7, IL6, IL-1beta mRNA in enteric glia.

97 nd TNF-alpha in the ilea of Tat+ mice and by enteric glia.

98 KEY POINTS: The role of enteric glial cell activity in the acute regulation of e

99 GFAP and other markers of enteric glial cells (eg, p75 and S100B), colocalized wit

100 Enteric glial cells (EGCs) produce soluble mediators tha

101 urce of astrocytes-like cells-referred to as enteric glial cells (EGCs).

102 ABSTRACT: Enteric glial cells are often implicated in the regulati

103 Primary enteric glial cells from C57BL/6 mice were incubated wit

104 Enteric glial cells that stained positive for glial fibr

105 h develop in the submucosa, might arise from enteric glial cells through hormone-dependent PKA signal

106 cover a new link between commensal bacteria, enteric glial cells, and ILC3s that is required for inte

107 Primary enteric glial cultures were generated from the VillinCre

108 roles for the transcription factor Ascl1 in enteric gliogenesis and neurogenesis.

109 poietic stem cell transplantation (HSCT) and enteric graft-versus-host disease (GVHD) remain unexplor

110 to detection being significantly shorter for enteric Gram-negative bacilli and enterococci (means, 3.

111 In enteric Gram-negative bacteria, Hfq is required for sRNA

112 yloid protein in the extracellular matrix of enteric Gram-negative bacteria.

113 hores, which are small molecules exported by enteric Gram-negative pathogens to acquire iron, an esse

114 were predictive of the occurrence of severe enteric GVHD (hazard ratio, 2.66; 95% confidence interva

115 over time were observed in individuals with enteric GVHD relative to those without, a finding accomp

116 L-17) production, which could have important enteric health implications.

117 These data demonstrate that a strictly enteric helminth infection can have remote protective an

118 Here we investigated the effects of strictly enteric helminth infection with Heligmosomoides polygyru

119 he small intestine and colon is required for enteric IFN-lambda antiviral activity.

120 relationship between the gut microbiota and enteric IL-17R signaling that controlled dysbiosis, cons

121 , outbreak cases were compared with non-STEC enteric illness cases, matched according to age group, s

122 that genetic defiency in TLR1 promotes acute enteric infection by the proteobacteria Yersinia enteroc

123 The Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE) did a study in three o

124 per 17 cells and increased susceptibility to enteric infection.

125 lts uncover a coordinated EC-IEL response to enteric infections that modulates lymphocyte energy util

126 including diets, smoking, lifestyle choices, enteric infections, appendectomy, air pollution, and the

127 Enteric infections, enteropathy and undernutrition in ea

128 n, and water quality are important to reduce enteric infections, which are frequent also among asympt

129 rm metabolic consequences of early childhood enteric infections.

130 ected in these mice nor was the formation of enteric lymphoid tissue, demonstrating that the onset of

131 rmore illustrated by impaired development of enteric lymphoid tissues in vitamin A-deficient mice.

132 ed emission factors to estimate county-level enteric methane emissions for cattle and manure methane

133 Commensal interactions between the enteric microbiota and distal intestine play important r

134 The enteric microbiota and the innate and adaptive immune sy

135 indings show that specific components of the enteric microbiota have distal effects on responses to l

136 ide evidence of metabolic diversification of enteric microbiota involved in the degradation of algal

137 The enteric microbiota is also phylogenetically and function

138 ctions between the intestinal mucosa and the enteric microbiota.

139 ne disorders can be treated by targeting the enteric microbiota.

140 f Cajal (ICC-IM) are closely associated with enteric motor nerve terminals and electrically coupled t

141 are closely associated with varicosities of enteric motor neurons and generate responses contributin

142 from the axial driveshaft than in the model enteric motor.

143 o reassess causes of diarrhoea in the Global Enteric Multicenter Study (GEMS).

144 l illness in children enrolled in the Global Enteric Multicenter Study was used to investigate the ge

145 The host mechanism of defense against enteric nematode infection remains to be fully understoo

146 We conclude that EGC-enteric nerve unit may be involved in IBS-like visceral

147 xpression within gastric epithelium expanded enteric nerves and promoted carcinogenesis.

148 uding the gastrointestinal tract to form the enteric nervous system (ENS) and hematopoietic organs (b

149 The enteric nervous system (ENS) develops from neural crest

150 root ganglia to the autonomic ganglia of the enteric nervous system (ENS) in the colon.

151 The enteric nervous system (ENS) is essential for digestive

152 The enteric nervous system (ENS) is organized into neural ci

153 The enteric nervous system (ENS) is the largest component of

154 S: Neural stem and progenitor cells from the enteric nervous system (ENS) might serve as a source of

155 The enteric nervous system (ENS) of the gastrointestinal tra

156 tion of the bowel, results from a failure of enteric nervous system (ENS) progenitors to migrate, pro

157 BACKGROUND & AIMS: The enteric nervous system (ENS) regulates gastrointestinal

158 The enteric nervous system (ENS) regulates numerous gastroin

159 The enteric nervous system (ENS) senses and reacts to the dy

160 a balanced microbial community and that the enteric nervous system (ENS), a chief regulator of physi

161 function is controlled by its own intrinsic enteric nervous system (ENS), but it is additionally reg

162 ointestinal tract, and more specifically the enteric nervous system (ENS), in search of an early biom

163 ointestinal physiology are controlled by the enteric nervous system (ENS), which is composed of neuro

164 ides a selective mechanism through which the enteric nervous system and innate immune system integrat

165 iation of progenitor cells in the developing enteric nervous system are controlled by molecules such

166 nism by measuring colonization in hosts with enteric nervous system dysfunction due to a mutation in

167 These defects included enteric nervous system hypoplasia, slow GI transit, dimi

168 and provide a paradigm for understanding the enteric nervous system in health and disease.

169 Here we examine development of the enteric nervous system in the basal jawless vertebrate t

170 Thus, differential engagement of the enteric nervous system may partake in bifurcating pro- o

171 Enteric nervous system neuropathy causes a wide range of

172 ade an important contribution to the ancient enteric nervous system of early jawless vertebrates, a r

173 The enteric nervous system of jawed vertebrates arises prima

174 und that control of differentiation of mouse enteric nervous system progenitor cells by EDN3 requires

175 tite and energy balance by engagement of the enteric nervous system through cannabinoid receptors.

176 hesized that Lewy pathology initiates in the enteric nervous system years prior to debut of clinical

177 fore alter innervation and morphology of the enteric nervous system, which may contribute to colonic

178 ecting the gut epithelium, immune system and enteric nervous system.

179 gulating the development and function of the enteric nervous system.

180 ng neurogenesis in the fully developed adult enteric nervous system.

181 odulating cholinergic neural reflexes in the enteric nervous system.

182 inhibits cholinergic neural reflexes in the enteric nervous system.

183 Enteric neural cells expressing the light-sensitive ion

184 whether neurons generated from transplanted enteric neural cells provide a functional innervation of

185 Enteric neural cells transplanted into the bowel give ri

186 varied with the age of the donors from which enteric neural cells were obtained.

187 Hirschsprung disease is caused by failure of enteric neural crest cells (ENCCs) to fully colonize the

188 roducing human pluripotent stem cell-derived enteric neural crest cells into developing human intesti

189 dence for the existence of a vagally derived enteric neural crest population in the lamprey.

190 toxin produces a massive over-activation of enteric neural secretomotor circuits.

191 Cell replacement of lost neurons using enteric neural stem cells (ENSC) is a possible therapy f

192 Lipopolysaccharide-induced in vitro enteric neurodegeneration requires the presence of palmi

193 mice to study the roles of these proteins in enteric neurogenesis and their cross regulation.

194 Mechanisms mediating adult enteric neurogenesis are largely unknown.

195 results suggest that colitis promotes rapid enteric neurogenesis in adult mice and humans through di

196 iew discusses the physiological relevance of enteric neuroimmune integration by summarizing the curre

197 motility and epithelial barrier function to enteric neuroinflammation.

198 For decades, interactions between the enteric neuromuscular apparatus and the central nervous

199 e that ENSC transplantation can modulate the enteric neuromuscular syncytium to restore function, at

200 pport the idea that 5-HT signaling regulates enteric neuronal development and can, when disturbed, ca

201 We examined enteric neuronal diversity and gastric function in Wnt1-

202 of adult precursors leads to an increase in enteric neuronal number, resulting in ganglioneuromatosi

203 enesis leaves unanswered the question of how enteric neuronal populations are maintained in adult gut

204 We show that enteric glia and all enteric neuronal subtypes appear to be derived from Ascl

205 Distinct enteric neuronal subtypes are formed in a temporally def

206 in enteric progenitor cells (such as MEF2C), enteric neurons (such as SOX4), or neuron subpopulations

207 phila indicate that Ret is expressed both by enteric neurons and adult intestinal epithelial progenit

208 he diversification into different classes of enteric neurons and glia during development.

209 in HIV-1 Tat and lipopolysaccharide (LPS) on enteric neurons and glia.

210 Evidence suggests that enteric neurons and intestinal immune cells share common

211 identify neuro-immune communication between enteric neurons and macrophages that induces rapid tissu

212 gnificant turnover and neurogenesis of adult enteric neurons and provide a paradigm for understanding

213 Clonally related enteric neurons exhibit synchronous activity in response

214 nal and mitochondrial functioning in primary enteric neurons of PD patients and their healthy partner

215 ut microbiota produces molecules that act on enteric neurons to influence gastrointestinal motility,

216 Activation of enteric neurons was inhibited by the nicotinic receptor

217 Electrical stimulation of endogenous enteric neurons was used as a control.

218 of mucosal serotonin and over-activation of enteric neurons, but its effects on gastrointestinal mot

219 particular anti-HuD, on visceral sensory and enteric neurons, which involves nicotinic and P2X recept

220 oot ganglion neurons, as well as cardiac and enteric neurons.

221 y, a well-characterized reflex controlled by enteric neurons.

222 tor tyrosine kinase is a defining feature of enteric neurons.

223 ility disorders caused by diseased or absent enteric neurons.

224 opment of cell-based therapies and models of enteric neuropathies.

225 e abundant in the WD with respect to driving enteric neuropathy and colonic dysmotility.

226 SC transplantation in a mouse model of human enteric neuropathy, the neuronal nitric oxide synthase (

227 These niches serve as sources of enteric neurotransmitters, such as epinephrine and norep

228 gens and persistence in an immune-privileged enteric niche.

229 teral nutrition for patients needing chronic enteric nutritional support.

230 ve fistulous tracks with posteriorly located enteric opening.

231 um assimilation differed from the classical "enteric paradigm" for nitrogen utilization.

232 Giardiasis, the most common enteric parasitic infection in the United States, causes

233 tects mice from acute colitis induced by the enteric pathogen Citrobacter rodentium Adoptive transfer

234 This enteric pathogen colonizes the anaerobic space of the lo

235 It is clear that the use of CIDTs for enteric pathogen detection, including both antigen detec

236 ria, while simultaneously protecting against enteric pathogen invasion.

237 In Vibrio parahaemolyticus, a significant enteric pathogen of humans, the roles of these regulator

238 controlled gene expression, including in the enteric pathogen Salmonella typhimurium.

239 rom the closely related food- and waterborne enteric pathogen Yersinia pseudotuberculosis A combinati

240 mans, and Y. pseudotuberculosis, the related enteric pathogen, deliver virulence effectors into host

241 increasing our understanding of this unique enteric pathogen.

242 ina will explain the advantages of CIDTs for enteric pathogens and discuss practical solutions for cl

243 t as narrow-spectrum therapeutics to inhibit enteric pathogens and reduce enterobacterial blooms.

244 pecies competition in environments harboring enteric pathogens and soil bacteria.

245 The intestinal epithelium can limit enteric pathogens by producing antiviral cytokines, such

246 The diagnosis of enteric pathogens in a timely and precise manner is impo

247 of the Luminex xTAG GPP for the detection of enteric pathogens in settings, like Vietnam, would drama

248 spective on why having access to isolates of enteric pathogens is essential for public health surveil

249 Among the 6 bacterial enteric pathogens tested, only Campylobacter jejuni/coli

250 Adenoviruses are respiratory, ocular and enteric pathogens that form complex capsids, which are a

251 late that continuous exposure of a number of enteric pathogens to deoxycholate stimulates a conserved

252 nt diagnostic tests (CIDTs) for detection of enteric pathogens were characterized as "a serious and c

253 ions, as in Zanzibar, are heavily exposed to enteric pathogens, but capable of rapidly clearing causa

254 Diarrhea is a host response to enteric pathogens, but its impact on pathogenesis remain

255 Among the enteric pathogens, enteropathogenic Escherichia coli (EP

256 n quickly changes upon exposure to different enteric pathogens, resulting in increased interepithelia

257 ion to promote successful associations among enteric pathogens, the microbiota, and the host.

258 obial responses involved in the clearance of enteric pathogens.

259 o study gut physiology and host responses to enteric pathogens.

260 tic treatment can increase susceptibility to enteric pathogens.

261 r, which serves as a primary defense against enteric pathogens.

262 se the incidence of symptomatic infection by enteric pathogens.

263 obiota at bay and defending against invading enteric pathogens.

264 tly higher than carbon dioxide (CO2) and its enteric production by ruminant livestock is one of the m

265 We used enteric progenitor cell (EPC) cultures and mice to study

266 ed according to their specific expression in enteric progenitor cells (such as MEF2C), enteric neuron

267 a can promote infection of several mammalian enteric RNA viruses, but the mechanisms and consequences

268 troviruses are among the least characterized enteric RNA viruses.

269 rarely, opportunistic microorganisms such as enteric rods and Staphylococcus aureus.

270 t MDA5 is crucial for the immune response to enteric rotavirus infection, a proposed etiological agen

271 onstrate that severity of disease induced by enteric Salmonella Typhimurium infection is strongly mod

272 which heterozygous missense variants in the Enteric Smooth Muscle actin gamma-2 (ACTG2) gene have be

273 d of promptly soluble, swellable/erodible or enteric soluble polymers, devices showing two-pulse rele

274 ficantly enhance suppression of co-occurring enteric species.

275 ants might elucidate the mechanisms by which enteric stem cells differentiate into neuronal subtypes

276 into the molecular mechanisms that underlie enteric symbiont-stimulated systemic immune system devel

277 ere, we elucidated the significance of giant enteric symbionts colonizing these fishes regarding thei

278 h tumor-derived nerve growth factor promotes enteric tumor innervation, and recruited nerves drive ca

279 e for IECs in IFN-lambda-mediated control of enteric viral infection, and these findings provide insi

280 .IMPORTANCE Sex bias in severe sequelae from enteric viral infections has been observed.

281 Type III interferons (IFN-lambda) control enteric viral infections in the gut and have been shown

282 as potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavir

283 ex should be considered in investigations of enteric viral replication and pathogenesis.

284 factors, such as the microbiota, that alter enteric viral replication, we sought to investigate coxs

285 We characterized the enteric virome and bacterial microbiome in a cohort of U

286 mmunity inhabiting the intestine termed "the enteric virome." Enteric viruses have intimate functiona

287 nt IFN-lambda-responsive cells in control of enteric virus infection in vivo Upon murine norovirus or

288 e I IFN may be the critical IFN for limiting enteric virus replication in the human intestine.

289 ts submitted to the National Respiratory and Enteric Virus Surveillance System during July 2005-June

290 Coxsackievirus is an enteric virus that initiates infection in the gastrointe

291 eria impact infection of poliovirus, a model enteric virus.

292 In mice, IFN-lambda was elicited by enteric viruses and acted on neutrophils to decrease oxi

293 t did not amplify genomes from 9 non-related enteric viruses and bacteria.

294 type I and type III IFN in restricting human enteric viruses are poorly characterized as a result of

295 The mechanism by which enteric viruses are sensed and restricted in vivo, espec

296 g the intestine termed "the enteric virome." Enteric viruses have intimate functional and genetic rel

297 ion could occur in tap water and thus confer enteric viruses protection against temperature and the c

298 Norovirus and rotavirus are prominent enteric viruses responsible for severe acute gastroenter

299 Much like for other enteric viruses, the current dogma states that astroviru

300 responding to IFN-lambda to control multiple enteric viruses.