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1 adA) is a major virulence factor of Yersinia enterocolitica.
2 e membrane topologies of PspB and PspC in Y. enterocolitica.
3 wing either i.p. or i.v. inoculation with Y. enterocolitica.
4 extensively in Escherichia coli and Yersinia enterocolitica.
5 tive immunity against Gram-negative Yersinia enterocolitica.
6 against the Gram-negative bacterium Yersinia enterocolitica.
7 riaceae, such as the enteropathogen Yersinia enterocolitica.
8 type III secretion system (T3SS) of Yersinia enterocolitica.
9 tive signal transduction pathway in Yersinia enterocolitica.
10 An aspirate from the axillary mass grew Y. enterocolitica.
11 es using the gastroenteric pathogen Yersinia enterocolitica.
12 ted with the AHL-producing pathogen Yersinia enterocolitica.
13 AHLs to mimic a constant interaction with Y. enterocolitica.
14 in naive macrophages infected with Yersinia enterocolitica.
15 n of FtsQ from Escherichia coli and Yersinia enterocolitica.
16 nes in response to S. typhimurium but not Y. enterocolitica.
17 response to prolonged secretin stress in Y. enterocolitica.
18 s susceptible to the enteropathogen Yersinia enterocolitica.
19 ric infection by the proteobacteria Yersinia enterocolitica.
20 transmission for the enteropathogen Yersinia enterocolitica.
21 o alleviate transcriptional repression in Y. enterocolitica.
22 N-acylhomoserine lactone (AHL) profile of Y. enterocolitica.
23 y and specifically to the inv promoter of Y. enterocolitica.
24 ric lymph nodes after oral infection with Y. enterocolitica.
25 tive regulators of psp gene expression in Y. enterocolitica.
26 intestinal lymphatic tissue infected with Y. enterocolitica.
27 for the existence of three subspecies of Y. enterocolitica.
28 s, Yersinia pseudotuberculosis, and Yersinia enterocolitica.
29 ellin of Salmonella Typhimurium and Yersinia enterocolitica.
30 se (LD(50)) following oral infection with Y. enterocolitica.
31 o intravenous (i.v.) infection with Yersinia enterocolitica.
32 role of the Ysps during the life cycle of Y. enterocolitica.
33 lague, Yersinia pseudotuberculosis, Yersinia enterocolitica.
34 es, Yersinia pseudotuberculosis and Yersinia enterocolitica.
35 ssed by Yersinia pestis, but not by Yersinia enterocolitica.
36 compared to those infected with wild-type Y. enterocolitica.
37 h is the primary invasion factor of Yersinia enterocolitica.
38 y informative typing scheme available for Y. enterocolitica.
39 to reverse the uptake blockade imposed by Y. enterocolitica.
40 istant to orogastric infection with Yersinia enterocolitica.
41 spontaneously arising pathogenic Ab with Y. enterocolitica.
42 coccus aureus, Escherichia coli and Yersinia enterocolitica.
43 OmpC, and OmpF confirming reactivity with Y. enterocolitica.
44 thogenesis, including the bacterium Yersinia enterocolitica.
45 illus cereus, Escherichia coli, and Yersinia enterocolitica.
46 teins at their endogenous levels in Yersinia enterocolitica.
47 dA, which is the primary C4BP receptor of Y. enterocolitica.
48 ontyphoidal Salmonella species, and Yersinia enterocolitica.
50 t in all 47 low-pathogenicity strains and Y. enterocolitica 8081 but absent from all nonpathogenic 1A
51 (99.4 to 99.8), and 0.96 (0.93 to 0.99); Y. enterocolitica, 99.0% (94.8 to 99.8), 99.9% (99.8 to 99.
53 obacter jejuni), Shigella flexneri, Yersinia enterocolitica, adenovirus, and Strongyloides fulleborni
55 limatization of the psychrotolerant Yersinia enterocolitica after a cold shock from 30 degrees C to 1
56 , we engineered EHEC to express the Yersinia enterocolitica AHL synthase gene yenI, which constitutiv
57 We find that IECs infected with Yersinia enterocolitica, an enteric pathogen, use beta1 integrins
60 ive clearance of the ileal pathogen Yersinia enterocolitica and an elevated inflammatory cytokine res
65 antipathogenic effects in the gut against Y. enterocolitica and highlight the need to investigate the
66 l)-l-homoserine lactone (3-oxo-C6-HSL) in Y. enterocolitica and inhibit QS-associated biofilm maturat
67 secretes (Yops), prevents phagocytosis of Y. enterocolitica and is required for disease processes in
68 e Yop secretion protein (Ysc) M2 of Yersinia enterocolitica and LcrQ of Y. pestis, formerly described
69 higella spp., Campylobacter spp. or Yersinia enterocolitica and matched each with up to 4 unexposed s
74 irst three-dimensional structure of Yersinia enterocolitica and Shigella flexneri injectisomes in sit
75 cylhomoserine lactones (AHLs) produced by Y. enterocolitica and upregulates the expression of an inva
76 ttle overlap between the RovA regulons of Y. enterocolitica and Y. pestis despite the fact that RovA
79 are conserved in Yersinia, divergence of Y. enterocolitica and Y. pseudotuberculosis/Y. pestis durin
80 ences between Yersinia enterocolitica subsp. enterocolitica and Yersinia enterocolitica subsp. palear
82 h is positively regulated by RovA in both Y. enterocolitica and Yersinia pseudotuberculosis while neg
84 nce method was 1.2% ETEC, 0.1% Vibrio, 0% Y. enterocolitica, and 0% P. shigelloides Compared to the r
85 identified the Salmonella species, Yersinia enterocolitica, and Campylobacter species but failed to
86 mon food pathogens, including E. coli and Y. enterocolitica, and could even detect Salmonella spp. fr
87 ethods for the detection of ETEC, Vibrio, Y. enterocolitica, and P. shigelloides in stool specimens f
88 10-fold higher than that of the wild-type Y. enterocolitica, and there are significant inflammatory r
89 , E. coli O157:H7, Vibrio cholerae, Yersinia enterocolitica, and toxigenic Clostridium difficile), pa
91 this study we show that PspB and PspC of Y. enterocolitica are dual function proteins, acting both a
92 ar Typhimurium (S. typhimurium) and Yersinia enterocolitica are enteric pathogens capable of colonizi
93 spectroscopy, we show that in live Yersinia enterocolitica bacteria these soluble proteins form comp
100 rally dynamic gene expression patterns of Y. enterocolitica biovar 1B through the course of an in vit
101 opened with the discovery of the Ysps of Y. enterocolitica Biovar 1B, which are translocated into ho
105 dritic cells, and a yopP mutant of a live Y. enterocolitica carrier vaccine elicited effective primin
110 ytxAB genes are not closely linked in the Y. enterocolitica chromosome, and whereas ytxR is present i
111 curring in response to S. typhimurium and Y. enterocolitica colonization of PP using Affymetrix GeneC
112 ate a diverse collection of 94 strains of Y. enterocolitica consisting of 35 human, 35 pig, 15 sheep,
114 itial examination of the effectiveness of Y. enterocolitica cya and crp mutants to stimulate protecti
115 The enteropathogenic bacterium Yersinia enterocolitica deactivates TLR-induced signaling pathway
116 coccus aureus, Escherichia coli and Yersinia enterocolitica--demonstrated that the zone of inhibition
117 n that a number of RovA-regulated loci in Y. enterocolitica do not have orthologues in Y. pestis and
118 few intestinal pathogens, including Yersinia enterocolitica, do produce acyl-HSLs, and Salmonella can
120 These findings add a new aspect of how Y. enterocolitica effectively evades the host complement sy
121 retion system of the human pathogen Yersinia enterocolitica enabled efficient identification of secre
122 irus, rotavirus A, Vibrio cholerae, Yersinia enterocolitica, Entamoeba histolytica, Cryptosporidium s
123 spp., Vibrio spp., Vibrio cholerae, Yersinia enterocolitica, enteroaggregative E. coli, enteropathoge
124 tool specimens for the detection of Yersinia enterocolitica, enterotoxigenic Escherichia coli (ETEC),
127 udotuberculosis and Y. pestis and YopP in Y. enterocolitica has been shown to regulate host immune re
129 in the genomes of E. coli O157:H7, Yersinia enterocolitica, Helicobacter pylori, and Vibrio cholerae
131 al the complete set of genes expressed by Y. enterocolitica in response to infection and provide the
132 on of Ysps with Yop effectors secreted by Y. enterocolitica indicated that YspG, YspH, and YspJ have
137 inflammatory cytokines in the control of Y. enterocolitica infection in IL-6(-/-) mice was undertake
138 ribed here compare oral S. typhimurium or Y. enterocolitica infection in stromelysin-1 (MMP-3)-defici
140 rant acute inflammatory response to Yersinia enterocolitica infection leads to long-lasting shifts in
143 Establishment of S2 cells as a model for Y. enterocolitica infection provides a versatile tool to el
144 of 7-day-old and adult mice to orogastric Y. enterocolitica infection were assessed in 50% lethal dos
145 nt secretion of IL-8 in response to Yersinia enterocolitica infection were dependent on extracellular
146 (1) receptor is important for controlling Y. enterocolitica infection within the Peyer's patches and
147 -6 plays an anti-inflammatory role during Y. enterocolitica infection, and in other systems IL-6 has
148 g protective roles for CD4 T cells during Y. enterocolitica infection, vaccinating mice with a 16-ami
159 ive surveillance for laboratory-confirmed Y. enterocolitica infections, defined as the isolation of Y
165 hanisms in which the enteropathogen Yersinia enterocolitica is able to disseminate from the lumen of
171 The salicylate synthase, Irp9, from Yersinia enterocolitica is involved in the biosynthesis of the si
174 Escherichia coli (EHEC) isolates, 2 Yersinia enterocolitica isolates, 2 Campylobacter species, and 23
176 as prevented when mice were infected with Y. enterocolitica lacking YopP or YopH, two critical effect
177 neonatal mice with low doses of virulent Y. enterocolitica leads to vigorous intestinal and systemic
179 oan (Toxoplasma gondii), bacterial (Yersinia enterocolitica, Listeria monocytogenes, and Mycobacteriu
184 on-ready tetrasaccharide of O-PS of Yersinia enterocolitica O:50 strain 3229 and the trisaccharide of
186 s KIM D27 LcrV (LcrV(D27)) bind LcrV from Y. enterocolitica O:9 strain W22703 (LcrV(W22703)) or O:8 s
187 no effect on extracellular nonsiderophilic Y enterocolitica O8 or Staphylococcus aureus Hepcidin anal
188 derophilic extracellular pathogens (Yersinia enterocolitica O9) by controlling non-transferrin-bound
190 t interactions between S. Typhimurium and Y. enterocolitica or that the SdiA regulon members do not f
191 a infections, defined as the isolation of Y. enterocolitica or unspeciated Yersinia from a human clin
194 a regulatory role for this lectin during Y. enterocolitica pathogenesis, mice lacking Gal-1 showed i
195 ressed in mucosal tissues, contributes to Y. enterocolitica pathogenicity by undermining protective a
196 2 recombined with a close relative of the Y. enterocolitica phage phiYeO3-12 to yield progeny phages,
200 e early precursor B cells are expanded by Y. enterocolitica porins to undergo somatic hypermutation t
201 ngle factor mediating serum resistance of Y. enterocolitica, presumably by binding C4b binding protei
202 (A) modified with C16:0 predominated, and Y. enterocolitica produced a unique tetra-acylated lipid A.
205 rall, these studies support the idea that Y. enterocolitica promotes the development of highly inflam
206 in Yersinia pseudotuberculosis and Yersinia enterocolitica prompted the model in which LcrQ negative
211 ore, PspG is the missing component of the Y. enterocolitica Psp regulon that was previously predicted
216 dence that it is the C-terminal domain of Y. enterocolitica PspC (PspC(CT)) that interacts directly w
221 dent and distantly related TTS systems of Y. enterocolitica recognize protein substrates by a similar
223 ion with the model enteric pathogen Yersinia enterocolitica reduces the mean time to death by 1 day (
225 ogenous chromosomally encoded proteins in Y. enterocolitica revealed discrete complexes corresponding
227 protein reporters, we determined that the Y. enterocolitica rovA (rovA(Yent)) promoter is weaker than
229 In Yersinia pseudotuberculosis and Yersinia enterocolitica, RovA regulates expression of the invasio
232 he rfaH genes from Vibrio cholerae, Yersinia enterocolitica, S. enterica serovar Typhimurium, and Kle
234 ches of mice infected orogastrically with Y. enterocolitica serotype O:8 compared with noninfected ho
235 Sequence analysis of the JB580v strain of Y. enterocolitica shows that, due to a premature stop codon
236 pestis) was obtained with 1 (of 10) Yersinia enterocolitica strains and 2 (of 10) Yersinia pseudotube
237 cannot block type III injection by Yersinia enterocolitica strains and suggested that lcrV polymorph
240 unable to block the type III injection of Y. enterocolitica strains, expression of lcrV(W22703) or lc
244 ia species, and differences between Yersinia enterocolitica subsp. enterocolitica and Yersinia entero
247 t the RovA regulon may be dispensable for Y. enterocolitica systemic disease and inflammatory respons
248 s maltophilia, Vibrio cholerae, and Yersinia enterocolitica T2S-expressing plant pathogens include Di
249 d to the N-terminal fragment of the Yersinia enterocolitica T3S substrate YopE, are effectively deliv
254 nic Yersinia pseudotuberculosis and Yersinia enterocolitica) that mediate a low-calcium response.
255 CSC-box into a plasmid-bound lacZ gene in Y. enterocolitica, the mRNA of this construct was cleaved w
256 the Ysa TTS system impacts the ability of Y. enterocolitica to colonize gastrointestinal tissues.
257 In this study, we tested the ability of Y. enterocolitica to modulate intracellular IL-1alpha-depen
261 To subvert the host's immune response, Y. enterocolitica uses a type III secretion system consisti
263 that the Ysa and Ysc TTSSs contribute to Y. enterocolitica virulence by exporting both unique and co
269 screened transposon insertion mutants of Y. enterocolitica W22703 for defects in type III secretion
273 he bacteria to colonize neonatal tissues; Y. enterocolitica was readily detectable in the intestine a
274 outer membrane adhesin/invasin from Yersinia enterocolitica, was detected in purified outer membrane
275 -coil adhesin homologous to YadA of Yersinia enterocolitica, was hypothesized to mediate the interact
276 ical properties of YscN and YscL of Yersinia enterocolitica, we have characterized them as the ATPase
277 to host cell uptake of S. Typhimurium and Y. enterocolitica, we investigated how each pathogen influe
279 responses elicited in neonates exposed to Y. enterocolitica were associated with long-term protection
280 val of MMP-3-deficient mice infected with Y. enterocolitica when compared with littermate controls.
281 a Gram-negative bacterial pathogen, Yersinia enterocolitica, when subjected to low temperature and se
282 coli, Salmonella enterica and also Yersinia enterocolitica, where it is essential for virulence.
283 yopP-deficient strain than with wild-type Y. enterocolitica, whereas only modest increases occurred i
284 osed of ~22 copies of SctQ (YscQ in Yersinia enterocolitica), which require the presence of YscQC, th
285 ons were isolated in cya and crp of Yersinia enterocolitica, which encode adenylate cyclase and the c
286 a marcescens, Escherichia coli, and Yersinia enterocolitica, which have some similarities in their MA
287 mon to three pathogenic Yersinia species: Y. enterocolitica, Y. pseudotuberculosis, and Y. pestis.
289 g model of factor H to YadA and show that Y. enterocolitica YadA recruits C3b and iC3b directly, with
291 ivity, we have characterized the OGL from Y. enterocolitica, YeOGL, on oligogalacturonides and determ
293 The type III secretion signal of Yersinia enterocolitica YopN was mapped using a gene fusion appro
294 We report the MgADP structure of Yersinia enterocolitica YopO in complex with actin, which reveals
297 Using a genetic approach, a collection of Y. enterocolitica Ysa TTS mutants was generated by mutagene
298 osttranscriptional gene regulation, Yersinia enterocolitica yscM1 and yscM2 as well as Yersinia pesti
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