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1 d aflibercept alone accounted for 95% of the entire $1.9 billion in drug reimbursements ophthalmologi
2 ariations and spatial-segmentation along the entire 1100 km-long Cascades Arc.
3 eplisomes is responsible for duplicating the entire 4.6 Mbp circular chromosome.
4  studied the effect of overexpression of the entire 4.8 kb miR-183 family cluster, including the inte
5 3 (SE = 0.017) survival probability over the entire 500 km study area compared to 0.199 (0.012) for t
6  within a membrane-bound compartment for the entire 6-day time course.
7  response, with equivalence concluded if the entire 95% CI was within a margin of -12% to 12%.
8 on that is genetically more diverse than the entire A1/D1 East cluster caused the sudden emergence of
9 erstanding the structure and mechanism of an entire ABC transporter superfamily and the many diverse
10 tes, the model can successfully simulate the entire adsorption data set over all uranium loadings, pH
11 sociated DBP formation are changed during an entire algal life cycle.
12 entify conformational changes throughout the entire AMPA receptor that accompany activation and desen
13 a) based on repeated measurements across the entire analytical procedure is 0.6 per thousand for delt
14 ion of coeluting isobaric species across the entire analytical space.
15                  Direct visualization of the entire anastomosis was improved with 3D ultrasound.
16 ther than lower expression levels across the entire ancestral expression domain.
17 accharomyces species complex, and across the entire and diversified subphylum of Saccharomycotina.
18 n improvement, as breeders have selected for entire and lobed leaf morphs resulting from a single loc
19 major functional networks extend through the entire animal and are activated selectively during longi
20 en theory and experiment is achieved for the entire applied frequency range and the wide bipolar bias
21 ic region, which comprises about half of the entire Arctic watershed.
22 ey miRNA pathway genes Dicer, Dgcr8, and the entire Argonaute gene family (Ago1, 2, 3, and 4).
23  related animal models and classification of entire assay descriptions.
24                                          The entire assay procedure involved addition of the stable i
25 ed evidence of continued maturation over the entire assessment period.
26  to secure sufficient doses to vaccinate the entire at-risk population-approximately 1 million people
27  spectrotemporal-based representation of the entire auditory scene, with both attended and unattended
28  (0.305 diopter [D]) absolute error over the entire axial length range, and was comparable with the f
29 h well-known methods and was better over the entire axial length range.
30 ts extensively in axons, spanning nearly the entire axonal shaft of mature neurons.
31 se resulted in hypoxic conditions across the entire Baltic sea as revealed by multiple sedimentary re
32        We found neural representation of the entire behavioural task, including activity that formed
33  are observed to lose specificity across the entire binding site.
34 sels connect multiple systems throughout the entire body and allow organs to interact via circulating
35 sing the geometric coverage to encompass the entire body, sensitivity can be increased by a factor of
36 redominant activity-evoked change across the entire bouton population.
37 chniques, but high-resolution examination of entire brains remains a challenge.
38  red-listed, declining seabird, across their entire breeding range.
39   The 4D spectral function rho(EB; k) in the entire bulk Brillouin zone and 6 eV binding-energy (EB)
40 ntrast-enhanced US showed enhancement of the entire bulk of the tumor, whereas gadolinium-enhanced T1
41 ed PPC oncology investigation to include the entire cancer continuum and the voices of patients.
42 s next generation sequencing (NGS), mean the entire cancer genome or parts of it can now be sequenced
43 urface antigens, metabolites, miRNA, and the entire cell as well.
44        It also enables time-lapse studies of entire cell cultures in multiple imaging modalities.
45                                 Labeling the entire cell membrane allows one to demonstrate that, by
46 ding to extreme rainfall episodes across the entire central subcontinent.
47 ing pathways and effector systems across the entire cerebrovascular network in a highly orchestrated
48 edisposition gene, while the analysis of the entire coding region of the FANCM gene in familial index
49 cific survival after 5 years was 38% for the entire cohort (95% CI, 25%-51%); the disease-specific su
50  of breast cancer, representing 0.41% of the entire cohort and 7.56% of the subset with metastatic di
51 ogy members have benefited as funding of the entire cohort has decreased.
52                                    Among the entire cohort of SLK in this analysis, the cumulative di
53                    Median survival among the entire cohort with brain metastases was 10.0 months.
54                                    Among the entire cohort, Hispanic ethnicity, male sex, VAT, and HO
55 of overall and disease-free survival for the entire cohort, including patients with myeloid malignanc
56                                      For the entire cohort, postoperative radiation was associated wi
57                                   Across the entire cohort, there were no statistically significant v
58                                      For the entire cohort, with >163,772 person-years of observation
59 ethoxazole prophylaxis was introduced in the entire cohort.
60 isite measurements of 5-HT overflow from the entire colon.
61 nto gamergates (pseudoqueens) that can found entire colonies.
62 convenient data resources widely used by the entire community and offer some lessons on what makes a
63 to annual oral azithromycin treatment of the entire community or biannual treatment of children aged
64 hat the cytotoxicity observed comes from the entire complex and not from ligand-exchange.
65 down of either RhopH2 or RhopH3 disrupts the entire complex, interfering with organellar targeting an
66                                              Entire compounds were evaluated for their anticancer act
67 ance (COV) ranging from 2% to 8% across this entire concentration range.
68 carbon stocks of the tropical forests of the entire Congo Basin.
69 ch other to form a channel through which the entire contents of their granules is released.
70  detect the relative En/DM thickening to the entire cornea.
71                                          The entire corneal data of pachymetry and elevation of both
72          The study aimed to characterize the entire corneal topography and tomography for the detecti
73 or the microvasculature but interrogates the entire coronary circulation.
74 rwent vessel painting perfusion to label the entire cortex at 1 day post TBI followed by whole brain
75 eld suggests a boro rice yield loss over the entire country of 1.4-4.9 million tons annually, or 7-26
76 economic impact at a community level for the entire country.
77 ing HIV-1 genomes and allows us to track the entire course of infection in macrophages, a key target
78 g of the evolution of these neurons over the entire course of study.
79   The iPSYCH2012 sample is nested within the entire Danish population born between 1981 and 2005, inc
80 al tests, which compare the distributions of entire data sets, were used to determine if the ammonia
81 cant correlation between PCAN and VA for the entire dataset (r = 0.394, P = .005).
82  we performed hierarchical clustering on the entire dataset to investigate the underlying causal stru
83 ctional variants in CGC genes and across the entire dataset.
84  to be made at the start of the year for the entire dengue season.
85 ver a 1-mm lateral field of view through the entire depth of an intact aortic wall.
86 n Gadoteridol was far less retained, and the entire detected gadolinium was intact soluble GBCA, whil
87 y present in almost all patients through the entire disease spectrum and clinical course.
88 ggests that genetic variation can impact the entire distribution of the expression level.
89 e DNA-binding domains is decreased as if the entire domain is becoming globally stabilized.
90                                     Over the entire dose range, there are negative mortality dose tre
91 onide dry powder inhaler twice daily for the entire duration of the study using the approved dosages
92 o address this discrepancy, we expressed the entire ectodomain of mouse P-selectin as a monomer (sP-s
93 ness change for 14 endemic groups over their entire evolutionary histories without the need for fossi
94 at the RPE interdigitations extend along the entire external segment of the cones, we do not believe
95 of the SEC61G, yielding products lacking the entire extracellular ligand-binding domain of the recept
96 tional deletion of TGF-beta signaling in the entire eye, the retinal pigment epithelium (RPE), or the
97 r to that observed after the deletion in the entire eye.
98                                    Here, the entire family of CLE peptide-encoding genes was identifi
99     Counter to this expectation we find that entire FFLs are more likely than expected to resist the
100 equently provides an image in focus over the entire field of view without any beam scanning or imagin
101 lid basis for further investigations for the entire field.
102 ters support a metallic transport across the entire film.
103  phosphorylation-related assembly of RSs and entire flagella.
104 lex in order to maintain the function of the entire flagellar assembly.
105  on the ground, at cruise altitude, and over entire flight missions.
106 ly in recent decades that an overview of the entire flora has become possible.
107 otal score for events encountered during the entire follow-up experience for each patient.
108 d if they had received medication during the entire follow-up.
109 t pulmonary vein isolation and completed the entire follow-up.
110                          We conclude that an entire fusion cascade can be controlled by a GEF.
111 DRs in one design and atomic accuracy in the entire Fv in another.
112 tifying clusters of somatic mutations across entire gene families using protein domain models.
113 ve been traditionally thought to disrupt the entire gene function.
114                Although the dimension of the entire genome can be extremely large, only a parsimoniou
115 ensive studies of genetic diversity over the entire genome of human cytomegalovirus (HCMV), a signifi
116 ere relatively evenly distributed across the entire genome, and covered 98.6% of the reference genome
117 rovides a comprehensive understanding of the entire genome, overcomes limitations of traditional QTL
118 ort reads only from 16S rRNA genes, not from entire genomes.
119 ve Lgr5(-) cells that are able to repopulate entire glands, including the base, upon depletion of the
120 ed MUAC with WHZ.The mean +/- SD age for the entire group was 21 +/- 14 mo, WHZ was -1.18 +/- 1.23, h
121 d an overriding effect on risk-taking by the entire group, for reasons independent of their physiolog
122 main factor influencing air-breathing of the entire group.
123 cy to breathe air influence the behaviour of entire groups, and whether such influences vary in relat
124 s of an individual precipitation event to an entire growing season.
125 on marmoset (Callithrix jacchus), across the entire hearing frequency range.
126 nd-in-hand with functional maturation of the entire heart.
127           The period covered encompasses the entire history since the beginnings of chlorin synthetic
128 langes, respectively, both contribute to the entire host autopod, indicating that the autopod positio
129 keratin 14 promoter drives expression of the entire HPV8 early region (HPV8tg).
130 one function of Hsp90 without inhibiting the entire Hsp90 machinery.
131 t in delayed replication and condensation of entire human chromosomes.
132  large-scale quantitation of immune cells in entire human kidney biopsies.
133 tantly, CRISPR/Cas9-mediated ablation of the entire Id (Id1-4) family in mouse embryos leads to failu
134 the same object detector which processes the entire image at homogeneous high spatial resolution.
135                               We rewrote the entire ImageJ codebase, engineering a redesigned plugin
136                                          The entire immunosensor fabrication process was fast, requir
137          This data set, representative of an entire industrialized country, presents a reference poin
138 ts were exclusively breastfed throughout the entire intervention period of 12 mo.
139  and video and only 5.7% were exposed to the entire intervention.
140 portance of environmental filters during the entire invasion process for the facilitation or inhibiti
141 neys, especially when the tumor involves the entire kidney.
142  actin subunits typically diffuse across the entire lamellipodium before reassembling into the networ
143  and would have subsequently expanded to the entire lateral wall in outer hair cells.
144 r hair cells, whereas it was detected in the entire lateral wall of cochlear outer hair cells and had
145 E) ferrorelaxor terpolymer layer running the entire length of the fibre.
146 resent such intimate ER-PM contact along the entire length of the pores that no intermembrane gap is
147 ragments (60-79 aa), which together span the entire length of tropomyosin, were weak secretagogues.
148 ight nanobeams with a complete LOS along the entire length to nanobeams in which the LOS ranges from
149 se to fibroblasts that distribute across the entire lengths of regenerating fin rays.
150 ions entrain spiking activity throughout the entire LGN, in anaesthetized marmosets.
151  can entrain spiking activity throughout the entire LGN.
152 and-functional groups to the affinity of the entire ligand.
153  shifts from blue to red light, covering the entire light spectrum.
154 hich commonly involves the extraction of the entire list of chemicals mentioned in a document, includ
155 s suggestive of a field defect affecting the entire liver.
156 scripts, with increased transcription of the entire locus driving Flt1 upregulation in both EO-PE and
157 uced correlated atomic motion throughout the entire LRH-1 activation function surface, which was depe
158                            Results QV of the entire lungs was lower for patients with CF than for con
159 against P falciparum infection throughout an entire malaria season.
160 ecedented in silico experiment-simulating an entire mammal red blood cell lipid bilayer and cytoskele
161           Here we calculate 3D structures of entire mammalian genomes using data from a new chromosom
162                       Either deletion of the entire mce4 operon or single point mutations that elimin
163 , we determined that the drug penetrates the entire MCTS.
164 us, despite evolutionary conservation of the entire MeCP2 protein sequence, the DNA and co-repressor
165                   All-cause mortality in the entire Medicare population from 2000 to 2012.
166 r cell bodies subsequently move to cover the entire medulla.
167 esting that CSNK-1 prevents expulsion of the entire meiotic spindle into a polar body by negatively r
168 nanoparticles uniformly distributed over the entire membrane surfaces.
169  sagittal brain slices containing nearly the entire mesh electronics probe showed that the tissue int
170                    The beta-diversity of the entire microbial community, however, was related to PMP.
171                  Five articles evaluated the entire microbiome using genomic sequencing.
172 tudies that evaluated microbial biofilms and entire microbiomes to establish their similarities and d
173 on triggers GPIb-dependent transmigration of entire MKs into BM sinusoids.
174 ns have been reported to be missing from the entire monocot lineage, with two exceptions.
175                         Here we show that 1) entire moss individuals, dated by (14)C, survived throug
176 pproximately half of these cells survive the entire mouse lifespan.
177 cell markers are localized in basal layer of entire murine corneal epithelium.
178 ropic dispersion of CN nanospheres along the entire NB head nanotubes lead to creating of abundant el
179 cleoskeleton and cytoskeleton) that span the entire NE and mediate nuclear positioning [10-12].
180 med "worm hospital" allows us to perform the entire nerve regeneration studies, including on-chip axo
181  pathways and, perhaps more generally, their entire nervous system.
182 PN) caused a rapid, global regression of the entire network, with some vessels regressing >10 mm with
183  models, enabling experimental access to the entire neuromechanical control loop of vocal motor contr
184      Such hitherto unknown patterns over the entire North American continent have the potential to si
185 (64-113 pmol kg(-1)) extended throughout the entire North Pacific Subtropical Gyre (NPSG).
186                       The process integrates entire oligo pool amplification, error-removal, and asse
187 ul competition for electron donor within the entire organohalide-respiring microbial community.
188 ar resolution, penetration depth through the entire organoid, and functional endpoints.
189     Low-dose RCEM was efficient in digesting entire pancreases to obtain higher yield (5535 +/- 830 a
190              Its capability to represent the entire pathology in relation to normal anatomical struct
191  affords, after reductive elimination of the entire PCO group, the unprecedented [L2 Ge-GeL2 ] comple
192                             NG-STAR uses the entire penA sequence, combining the historical nomenclat
193 gnostic biomarker that is present across the entire period of patient presentation, particularly in t
194  The failure-to-rescue rate was 4.4% for the entire period, but it significantly decreased after intr
195 00 men for each monthly ad exposure over the entire period.
196                                 Although the entire phenolic profile was diverse and differed among f
197 yanin contents, antioxidant capacity and the entire phenolic profile were investigated for extracts f
198 ) to impose consistent associations with the entire phenotype paths in predicting phenotype-gene asso
199 nces 78 Recent decades have seen declines of entire plant clades while other clades persist despite c
200  binding, is not evenly distributed over the entire plasma membrane but instead is highly enriched on
201 Using a quantitative approach to profile the entire plasma membrane proteome, we find that CMTM6 disp
202                       Concordantly, when the entire population of asymmetrically projecting neurons w
203  is the only method capable of exploring the entire population of free-floating planets down to Mars-
204                                   Within the entire population of MITEs sequences, 80.7% of them were
205 w changes at single synapses translate to an entire population of neurons.
206 geneous population eventually takes over the entire population.
207 n approach using SNP and DArT markers on the entire population.
208 og/m3 increment in PM2.5 exposure during the entire pregnancy was associated with 8.8% (95% CI, -14.1
209                                          The entire procedure is carried out at 6 degrees C or colder
210                                          The entire procedure takes approximately half an hour per mo
211                                          The entire procedure, from virus production to data analysis
212 example of how a single miRNA can control an entire process by acting on a crucial mediator; however,
213                        Most importantly, the entire process could be quickly completed within two hou
214                                    Since the entire process was performed in a fully automated way an
215 ement of retinoic acid (RA) signaling in the entire process.
216                                   Across the entire PROMISE cohort, this model was associated with th
217  cell-penetrating peptides and that both the entire protein and the peptide corresponding to the N-te
218 ical response by being coupled to nearly the entire protein, responding to both stabilizing and desta
219  large DNA fragment, oligopeptides, and even entire proteins in an implicit solvent.
220       Beginning with the library design, the entire protocol can be completed in 4-8 weeks (HyCoSuL s
221 xtrapolated to account for the length of the entire pWH1266 plasmid, the qPCR rate constants were 2-7
222 ts required for Pxr function, we deleted the entire pxr gene from a developmentally defective strain
223                                          The entire quantification process could be automatically per
224 fluids remains poorly understood because the entire quantity is challenging to measure.
225 N, premorbid body mass index (BMI) spans the entire range from underweight to obese.
226 imple stage for systematic derivation of the entire range of ectodermal cell types.
227 l assessment of dissociative symptoms in the entire range of mental disorders.
228 interact with almost equal facility over the entire range of pi systems studied, with the simple alke
229 nge of the physicochemical conditions in the entire reaction chamber can be reached in under 30 s.
230 nbiased alanine-scanning screen covering the entire region combined with quantitative electron micros
231                We show that deletion of this entire region results in a male-to-female conversion, wh
232 egy for reducing CRE transmissions across an entire region, particularly when implemented as early as
233        The other control group comprised the entire renal transplanted population in Uppsala.
234 macular" condition but one that involves the entire retina.
235 dity of TDA, D and Rh average values and the entire Rh distributions were obtained from the (poly)sac
236  (hpol) gamma have been shown to tolerate an entire RNA strand.
237 om the dorsal claustrum, extending along its entire rostral-caudal length.
238 ere, we present the cryo-EM structure of the entire SAGA complex where the major target of activator
239 sequencing of 97 samples collected along the entire salinity gradient at two-month intervals in 2014.
240 ween FRC use and severe periodontitis in the entire sample (odds ratio [OR]: 1.7, 95% confidence inte
241 important predictors of cognition across the entire sample of depressed subjects and HR.
242                         By recirculating the entire sample through the antibody coated tube, accumula
243 ingle-crystalline bulk structure through the entire sample volume.
244                                       In the entire sample, telomere length was positively associated
245  foveated object detector that processes the entire scene with varying resolution, uses retino-specif
246  adaptation required for the assembly of the entire secretion machine.
247 that modulate and augment key aspects of the entire secretory pathway, whereas maladaptive UPR output
248 rom AF after a single FIRM procedure for the entire series was 95% (PAF), 83% (PeAF), and 82% (LPeAF)
249 ructure to generate a continuum model of the entire sheath that also couples to a model of the viral
250  of high FGF and low BMP activity across the entire skin reveals a latent dermal capacity to undergo
251 ecific groups, whereas little is known about entire soil networks.
252 challenge, we propose the utilization of the entire solar spectrum by redirecting solar photons to ma
253  We then measured listeners' priors over the entire space of two- and three-interval rhythms.
254 as used for the multivariate analysis of the entire spectral features employed.
255 ve is sufficient to ensure readiness for the entire spectrum of independent practice.
256 the multipotent capacity to reconstitute the entire spectrum of memory and effector T cell subsets.
257 water isotopes from the snowpack through the entire spring melt runoff period for two years.
258 ly reconstitute the heterogeneity within the entire starting population, suggesting that GATA express
259 ccounting perspective, forest SOC is not the entire story.
260                          With regards to the entire studied series, the overpotential and Tafel slope
261                                      For the entire study cohort, median overall survival was 11.1 mo
262  was 82 months (range, 6-329 months) for the entire study cohort; 363 patients (63%) underwent survei
263 butryn mass balance could be closed over the entire study period of 120 days and showed that relative
264 t differ between the treatment groups in the entire study population (HR 0.93, 95% CI 0.83-1.04; p=0.
265  and R(2)=0.32 for normalized TKEsys) in the entire study population including control subjects, whil
266 -positive cancer and overall survival in the entire study population.
267 nts, investigators, other site staff and the entire study team including those assessing outcomes dat
268                                           An entire subset of antibody-positive patients, anti-N-meth
269 emented with interviews of actors across the entire supply chain.
270 rent from other contemporary approaches, the entire system is treated quantum mechanically and neithe
271 tegrated design of resource reuse across the entire system.
272 Unlike nonselective approaches targeting the entire T cell population, TRBC-targeted immunotherapy co
273 pressed miRNAs (DEMs) were identified in the entire TAA-treatment course.
274 the fiber results in light emission from the entire taper surface, achieving broader and more efficie
275 all suppression of alpha activity across the entire task but also diminished the frequency of these m
276 istribution of alien species richness for an entire taxonomic class.
277 s opportunity for systematic analyses of the entire TCGA NSCLC cohort, including comparisons and cont
278 gassing behavior with no-hysteresis over the entire temperature and water activity range considered h
279 etry index of the 95th percentile within the entire thalamus at 1 year was independently associated w
280 time derivative of force (dF/dt) predict the entire time course of transient IFRs in muscle spindle I
281  Organization recommends annual treatment of entire trachoma-endemic communities, although children t
282                                     Over the entire trial, we noted significant worsening on tests of
283 ls and the hemodynamic properties across the entire tumor can be quantitatively evaluated with high s
284 therapies that will be effective against the entire tumor.
285 d [Formula: see text], respectively, for the entire U.S. population.
286 g/day and 1.4 mug/day, respectively, for the entire U.S. population.
287 tter analyze changes in HCC incidence in the entire United States.
288 d insurance claims for over one-third of the entire US population to create a subset of 128,989 famil
289   Imaging demonstrated a preservation of the entire vascular tree patency.
290 sels were closed using particles filling the entire vascular tumor.
291 rsed RNA packaging signals mapping along the entire viral genome" play the critical role in polioviru
292 with a resulting palette spanning almost the entire visible range.
293 t high peak reflectivities (>96%) across the entire visible spectrum and wide spectral stop-band widt
294 r emission wavelength was tunable across the entire visible spectrum by tuning the excitation wavelen
295  mechanism that exerts its action across the entire visual field.
296 m of the TiO2-coated glass wafer, before the entire wafer is exposed to UV irradiation.
297 A-t), were estimated and compared across the entire white matter skeleton between groups, and correla
298 cific and rescued by a fosmid containing the entire wild-type CaMKII locus, but only viability and Ca
299 e development of pipelines orchestrating the entire workflow and optimizing usage of available comput
300 in tropical canopies is near maximal for the entire year, implying that seasonal changes in LAI have

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