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1 s phylogenomics (phylogenetic inference with entire genomes).
2 e-tuning gene expression patterns across the entire genome.
3 mited number of reporters holds true for the entire genome.
4 measurements of DNA binding events across an entire genome.
5 ity pedigrees that failed to link across the entire genome.
6 major heteroduplex type strains by using the entire genome.
7 dominant model yielded no signals across the entire genome.
8 terns of specific protein molecules over the entire genome.
9 frican versus European ancestry and span the entire genome.
10 ndous amount of gene expression data for the entire genome.
11 n considering pairwise similarity across the entire genome.
12 candidate genes and, in the future, from the entire genome.
13 mbly graph is a single edge encompassing the entire genome.
14 synonymous substitution and occur across the entire genome.
15 re analysis requires scanning markers of the entire genome.
16 oximately 265 base pair) resolution over the entire genome.
17 ement insertions and deletions that span the entire genome.
18 ut fraction, which was representative of the entire genome.
19 e in vivo targets of Prospero throughout the entire genome.
20 scan for the existence of QTL throughout the entire genome.
21 al of cyclobutane pyrimidine dimers from the entire genome.
22 ing large chromosomal regions, much less the entire genome.
23 ions or from panels of markers that span the entire genome.
24 ased on 876 fragments selected to sample the entire genome.
25 en genes from one process and genes from the entire genome.
26 asible to biochemically screen an organism's entire genome.
27 ymes and to identify interactions across the entire genome.
28 The actual QTL are detected by scanning the entire genome.
29 number of transcription units present in an entire genome.
30 the estimated 44,027 candidate genes of its entire genome.
31 of transcription factors binding sites in an entire genome.
32 he prevalence and nature of Pack-MULEs in an entire genome.
33 V infection, using HCV peptides spanning the entire genome.
34 he genome and have shaped both genes and the entire genome.
35 es using inbred strains that vary across the entire genome.
36 aluate effects of chromosome segments of the entire genome.
37 which accounts for approximately 3% of their entire genome.
38 cal translation and proteolytic digest of an entire genome.
39 rom the majority phylogeny estimated for the entire genome.
40 ion factor (TF) binding events throughout an entire genome.
41 the total number of markers to 408 over the entire genome.
42 netic effects associated with markers of the entire genome.
43 ts on microarrays expands to accommodate the entire genome.
44 enes, corresponding to about 0.5-1.0% of the entire genome.
45 data and training itself automatically on an entire genome.
46 ction of specific probes for each gene in an entire genome.
47 a single gene than the number of genes in an entire genome.
48 ption of a 358 RNA that is homologous to the entire genome.
49 and their associated RNA species across the entire genome.
50 , a form of packaging that inactivates their entire genome.
51 by providing simultaneous examination of the entire genome.
52 permethylated and hypomethylated, across the entire genome.
53 assess the degree of mutagenesis across the entire genome.
54 al transcription extending across nearly the entire genome.
55 a set of targeted regions as well as of the entire genome.
56 can be analyzed in light of an individual's entire genome.
57 a panel of contiguous cDNAs that spanned the entire genome.
58 bound motifs from unbound motifs across the entire genome.
59 hly variable parts of the genome or over the entire genome.
60 not only to individual genes, but across the entire genome.
61 se are in the top 60 prion candidates in the entire genome.
62 mal levels of gene expression throughout the entire genome.
63 dividuals and that are representative of the entire genome.
64 tributed across all seven chromosomes of the entire genome.
65 namics directly over long periods and across entire genomes.
66 approach for characterizing and quantifying entire genomes.
67 ory interactions vary between species across entire genomes.
68 genetic studies to phylogenomics analysis of entire genomes.
69 genes, enzymes, metabolic pathways, and even entire genomes.
70 cture and patterns of DNA methylation across entire genomes.
71 n of oxygenic photosynthesis on the scale of entire genomes.
72 no convenient means to search for them over entire genomes.
73 o the assembly of overlapping DNA reads into entire genomes.
74 cy of MSCAN allows for predictive screens of entire genomes.
75 s a model for constructing physical maps for entire genomes.
76 annotate large numbers of gene products for entire genomes.
77 ed signaling domains of the RRs and HKs from entire genomes.
78 A-binding protein and, via microchips, along entire genomes.
79 ort reads only from 16S rRNA genes, not from entire genomes.
80 models of genomic regions, chromosomes, and entire genomes.
81 ngth and truncated insertions throughout the entire genome, a strong preference for gene-poor regions
82 -density oligonucleotide arrays spanning the entire genome allowed the accurate annotation of thousan
84 that, despite their conservation across the entire genome and in different cell types, chromatin pat
85 contain a large number of markers across the entire genome and most of them have little or no effect
88 s variation in transcript levels is over the entire genome and to what extent individual differences
89 or genes is >1000-fold more diverse than the entire genome and varies between genetically identical i
90 red painting greatly reduces the need to map entire genomes and helps focus only on relevant regions
93 nucleotide mutations were identified in the entire genome, and both were located in the capsid gene:
94 ere relatively evenly distributed across the entire genome, and covered 98.6% of the reference genome
95 is setting, it is unnecessary to sequence an entire genome, and target capture methods can be applied
96 ation of overlapping regions over almost the entire genome, and the virus was provisionally designate
97 rovide training data, running TWINSCAN on an entire genome, and then performing RT-PCR and direct seq
98 etic and natural genes, genetic pathways and entire genomes, and could be a useful molecular engineer
99 the universal probe design principal across entire genomes, and the subsequent creation of a complem
101 Sequences from both the training set and the entire genome are taken into account, in order to discri
102 ers within candidate genes or throughout the entire genome are typed and height data from childhood t
103 c selection (GS), all the markers across the entire genome are used to conduct marker-assisted select
107 bers were genotyped for markers covering the entire genome at an average spacing of approximately 9 c
108 irst comprehensive DNA methylation map of an entire genome, at 35 base pair resolution, using the flo
109 use in evaluating the genetic effects of the entire genome because they require evaluation of multipl
111 the ENCODE regions are representative of the entire genome by estimating the rate of nucleotide subst
112 sulted from two rounds of duplication of the entire genome by polyploidization (the 2R hypothesis).
115 ized eggs develop as diploid females, so the entire genome can be screened for recessive zygotic muta
118 g runs today can produce as much data as did entire genome centers a few years ago, the need to proce
120 tic quantitative trait loci (QTL) across the entire genome continues to be a formidable challenge for
122 lution, ordered restriction map covering the entire genome could serve as a scaffold for the alignmen
123 urrent technologies cannot be applied on the entire genome data due to various technical caveats.
128 ectively reconstruct the 3D structures of an entire genome due to the difficulty of handling noisy an
132 l system to simultaneously screen nearly the entire genome for both standing genetic variation within
134 brary that provides 2.6-fold coverage of the entire genome for clones that affect macrophage infectio
136 erally, the method could be used to scan the entire genome for evidence of recent positive selection.
137 ds of a double-strand break (DSB) search the entire genome for homologous templates that can be used
139 roduced statistical methods for searching an entire genome for quantitative trait loci (QTL) in exper
141 mited our ability to universally amplify the entire genome for subsequent sequencing or vaccine produ
142 stributions have enabled researchers to scan entire genomes for genes under selection, we anticipate
143 s provide an unprecedented ability to screen entire genomes for genetic changes associated with tumou
144 ecies precedes reproductive isolation of the entire genome, forming an early stage in the process of
146 precipitation of multiple regions across the entire genome from two KSHV-infected cell lines, BC-3 an
148 ed anew at the time of implantation when the entire genome gets methylated while CpG islands are prot
151 scribing these variation patterns across the entire genome, has been recently developed by the Intern
152 Genetic association studies which survey the entire genome have become a common design for uncovering
153 increase the rate of mutagenesis across the entire genome have been identified; however, how the rat
154 gonucleotide-based microarrays that span the entire genome have emerged as the preferred platform for
155 in genes from four eukaryotes for which the entire genomes have been sequenced: Homo sapiens, Drosop
156 s involving the simultaneous analysis of the entire genome in a high-throughput manner are expected t
157 distinct regions of essentiality across the entire genome in a statistically rigorous manner, while
158 ys, we analyzed the transcription across the entire genome in both normal human bronchial epithelial
159 arge numbers of common variants spanning the entire genome in disease and non-disease subjects has re
163 elic expression has become available for the entire genome in multiple human and mouse tissues and ce
166 an be applied to the spatial organization of entire genomes in organisms from bacteria to human.
168 , tested enough genetic markers to query the entire genome, in 17 American pedigrees (163 subjects) a
169 h-confidence TP63-binding regions across the entire genome, in primary human neonatal foreskin kerati
170 ence-based comprehensive coverage across the entire genome, including repetitive genomic regions typi
172 ome models at multiple levels, including the entire genome, individual chromosomes, and specific segm
176 y regulated and monitored to ensure that the entire genome is duplicated exactly once, without errors
177 hese origins must be coordinated so that the entire genome is efficiently and accurately replicated y
178 ry mouse embryonic fibroblasts (MEFs), whose entire genome is either exclusively paternal (androgenet
182 us, during follicle cell differentiation the entire genome is overreplicated as the cells become poly
185 icting regulatory sequences and enhancers in entire genomes is an important but difficult problem, es
186 gments, also known as contigs, instead of an entire genome, it is crucial to group them into operatio
187 s, but because assembly does not reconstruct entire genomes, it is necessary to bin genome fragments.
189 d by DNA shuffling with the recombination of entire genomes normally associated with conventional bre
191 to determine DNA copy number which uses the entire genome of a single chimpanzee as a competitor thu
193 ion of genetic information requires that the entire genome of an organism be faithfully replicated on
194 ed that it would be possible to sequence the entire genome of an uncultured marine viral community.
196 f new deletions that now cover virtually the entire genome of Drosophila, providing greater precision
197 he monocots, we describe the transfer of the entire genome of Festuca pratensis into Lolium perenne i
199 e extent of interstrain variation across the entire genome of HSV-1 in both coding and noncoding regi
200 ensive studies of genetic diversity over the entire genome of human cytomegalovirus (HCMV), a signifi
205 am searches for a given DNA motif within the entire genome of one species and uses the gene associati
206 library of congenic strains encompassing the entire genome of one strain on the background of the oth
207 of overlapping cosmids corresponding to the entire genome of RRV was capable of complementing oriLyt
210 wever, despite the genetic sequencing of the entire genome of the 1918 virus, many questions about th
214 ta-structural SCOP superfamilies against the entire genome of Thermotoga maritima, and make over a 10
219 To assess this hypothesis, we sequenced the entire genomes of 104 unrelated natives of the Arabian P
220 that drive medulloblastoma, we sequenced the entire genomes of 37 tumours and matched normal blood.
223 how structure-first comparative analysis of entire genomes of a pathogenic RNA virus enables compreh
224 ortly allow cost-effective sequencing of the entire genomes of affected individuals and their relativ
225 note that for the first time in history the entire genomes of all six parasites have been sequenced
226 ll soon enable high-throughput sequencing of entire genomes of cancer patients; however, determining
227 ried out a systematic replication study with entire genomes of human papillomavirus type 31 (HPV31),
228 en used to classify gene products across the entire genomes of human, and Drosophila melanogaster.
229 The sequencing of the human genome and the entire genomes of many model organisms has resulted in t
230 ve strength of selection on each gene in the entire genomes of Mycobacterium tuberculosis and Plasmod
231 Recently it has become possible to scan entire genomes of several individuals within a populatio
233 ic Research's 33 plant gene indices, and the entire genomes of the model dicot, Arabidopsis thaliana,
236 nges leading to epizootics, we sequenced the entire genomes of two subtype IC epizootic VEE virus str
240 -generation sequencing applied either to the entire genome or to a subset, such as a whole exome, has
241 RDA)), there is frequently a need to amplify entire genomes or cDNAs by PCR to obtain enough material
243 rovides a comprehensive understanding of the entire genome, overcomes limitations of traditional QTL
245 kingly direct mechanism by which recoding of entire genomes results from changes in utilization of a
246 sed by oxidative damage recovered across the entire genome revealed strong local-sequence biases of t
252 genome-wide scale, we have re-annotated the entire genome sequence of Chlamydia trachomatis (serovar
255 lant biology and the first plant to have its entire genome sequenced, belongs to one such group, the
258 genome deep-sequencing method that generates entire genome sequences from small amounts of clinical s
259 e a suffix-tree algorithm that can align the entire genome sequences of eukaryotic and prokaryotic or
262 candidate genes, chromosomal regions or the entire genome should encourage investigation of determin
263 the action of purifying selection across the entire genome, shows a strong inverse relationship with
264 ible to screen and analyze the expression of entire genomes, simultaneously assess large numbers of p
265 analysis of the homeodomain repertoire of an entire genome, that of the nematode Caenorhabditis elega
267 riments are widely used to determine, within entire genomes, the occupancy sites of any protein of in
268 dologies have evolved with the sequencing of entire genomes, the use of in vivo models to elucidate t
269 nalysis, and it measures selection across an entire genome; the method can readily be applied to a la
271 tion to this problem is to first amplify the entire genome, thus providing enough DNA for numerous su
272 regulated switch from endoreplication of the entire genome to amplification of the chorion gene clust
273 transcription factors must search through an entire genome to find their target sites in promoters.
274 allow for a powerful, unbiased review of the entire genome to localize common genetic variants that i
275 per base to index the human genome, allowing entire genomes to be loaded to memory, while multiple pr
277 To detect selenoproteins in Drosophila, the entire genome was analyzed with a novel program that sea
278 AC clones providing >25-fold coverage of the entire genome was end sequenced and fingerprinted by Hin
280 resolution and to extend the analysis to the entire genome, we analyzed a subset of these tumors (n =
283 e the effects of nascent duplications of the entire genome, we generated isogenic polyploid strains o
284 ng a panel of contiguous cDNAs that span the entire genome, we have assembled a full-length cDNA of t
286 When the sequences under consideration are entire genomes, we have the problem of multiple whole-ge
287 Eight overlapping fragments spanning the entire genome were amplified by reverse transcription-PC
290 whereby five contiguous cDNAs that span the entire genome were used to generate a full-length cDNA.
294 es to determine DNA methylation status of an entire genome, which has heretofore not been reported.
295 are heterogeneous in length and overlap the entire genome, which pose obstacles for high resolution
296 hes that would allow functional profiling of entire genomes will be helpful in elucidating the microb
297 onucleotide probe per 30 base pairs over the entire genome, with one every 6 bases for the intergenic
298 ural selection pressure across virtually the entire genome, with this adaptation occurring in differe
299 iations in multiple viral populations across entire genomes within a highly customizable framework, d
300 , these libraries allow us to reassemble the entire genome without the need of a reference sequence.
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