ライフサイエンスコーパス: eosinophil-derived neurotoxin

1 hancement of the ribonucleolytic activity of eosinophil-derived neurotoxin.

2 l the activities of RNase homologues such as eosinophil-derived neurotoxin and angiogenin that have r

3 n eosinophil-associated ribonucleases (i.e., eosinophil-derived neurotoxin and eosinophil cationic pr

4 sinophil-associated RNases (EARs): the human eosinophil-derived neurotoxin and eosinophilic cationic

5 ited the dose- and time-dependent release of eosinophil-derived neurotoxin and leukotriene C(4).

6 lized lactoferrin also stimulated release of eosinophil-derived neurotoxin and low levels of leukotri

7 se their cytotoxic granule proteins, such as eosinophil-derived neurotoxin and major basic protein, i

8 regions of RNase A and two other homologues, eosinophil-derived neurotoxin and onconase, all of which

9 tive against two major nonpancreatic RNases: eosinophil-derived neurotoxin and RNase-4; in all cases,

10 P2R-dependent release of a granule protein (eosinophil-derived neurotoxin) and cell death.

11 pancreatic RNase superfamily, human RNase-2 (eosinophil-derived neurotoxin) and RNase-4, which share

12 imulants, including defensins, cathelicidin, eosinophil-derived neurotoxin, and high-mobility group b

13 s also induced degranulation, as measured by eosinophil-derived neurotoxin, and IL-8 release, but not

14 In contrast, eosinophil-derived neurotoxin did not regulate fibroblas

15 s in decreased major basic protein (MBP) and eosinophil derived neurotoxin (EDN) mRNA expression in d

16 osinophil cationic protein (ECP or RNase 3), eosinophil-derived neurotoxin (EDN or RNase 2), eosinoph

17 way eosinophils (r(s) = 0.61), and levels of eosinophil-derived neurotoxin (EDN) (r(s) = 0.57) and IL

18 gent orthologs of the primate ribonucleases, eosinophil-derived neurotoxin (EDN) and eosinophil catio

19 f the two closely related ribonucleases, the eosinophil-derived neurotoxin (EDN) and eosinophil catio

20 The eosinophil-derived neurotoxin (EDN) and eosinophil catio

21 penia and preceding the appearance of plasma eosinophil-derived neurotoxin (EDN) and interleukin-5.

22 Although levels of eosinophil-derived neurotoxin (EDN) and major basic prot

23 onic protein, there was a marked increase in eosinophil-derived neurotoxin (EDN) both systemically an

24 i) the eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) genes.

25 es for eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) in primates belong t

26 Eosinophil-derived neurotoxin (EDN) is an eosinophil gra

27 tein (ECP), eosinophil peroxidase (EPO), and eosinophil-derived neurotoxin (EDN) on cultured human co

28 etion of cysteinyl leukotrienes (CysLT), and eosinophil-derived neurotoxin (EDN) release.

29 Leukocytes were counted and eosinophil-derived neurotoxin (EDN) was measured in sput

30 e of a post-translationally modified form of eosinophil-derived neurotoxin (EDN) with four extra resi

31 One of them is eosinophil-derived neurotoxin (EDN), a protein belonging

32 ucture of RI in complex with a third ligand, eosinophil-derived neurotoxin (EDN), and a mutational an

33 ral basis for recognition of a third ligand, eosinophil-derived neurotoxin (EDN), by single-site and

34 Eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN), the eosinophil secr

35 es contain an antimicrobial protein known as eosinophil-derived neurotoxin (EDN), which belongs to th

36 ween blood eosinophilia and IL-5, IL-13, and eosinophil-derived neurotoxin (EDN), which stayed consis

37 s group, RNase k6 is most closely related to eosinophil-derived neurotoxin (EDN), with 47% amino acid

38 ribonucleases-pancreatic RNase (hRNAse) and eosinophil-derived neurotoxin (EDN)-to incorporate cyste

39 at of a related eosinophil ribonuclease, the eosinophil-derived neurotoxin (EDN).

40 of the two eosinophil ribonucleases, ECP and eosinophil-derived neurotoxin (EDN)] remains controversi

41 of 2417 nucleotides at the two EAR loci, the eosinophil-derived neurotoxin (EDN, RNase 2) and eosinop

42 We have demonstrated that the human eosinophil-derived neurotoxin (EDN, RNase 2), a rapidly

43 The two eosinophil ribonucleases, eosinophil-derived neurotoxin (EDN/RNase 2) and eosinoph

44 scription of the secretory ribonuclease, the eosinophil-derived neurotoxin (EDN/RNase 2).

45 The eosinophil-derived neurotoxin (EDN/RNS2) is a member of

46 nule proteins (major basic protein [MBP] and eosinophil-derived neurotoxin [EDN]) by radioimmunoassay

47 and eosinophil degranulation products (e.g., eosinophil-derived neurotoxin, EDN).

48 Our observation that a change in eosinophil-derived neurotoxin function occurs only when

49 olved in a recently duplicated ribonuclease (eosinophil-derived neurotoxin) gene of higher primates.

50 The human eosinophil-derived neurotoxin (hEDN) is a secretory effe

51 studied: human pancreatic RNase, angiogenin, eosinophil-derived neurotoxin, onconase, and bovine semi

52 trate that chemokines fused with human RNase eosinophil-derived neurotoxin or with a truncated fragme

53 or basic protein [p < 0.001, r = 0.7353] and eosinophil-derived neurotoxin [p < 0.01, r = 0.7059]).

54 s paralleled IL-5 secretion, while levels of eosinophil-derived neurotoxin peaked at day 13 after tre

55 osinophils exhibited greater FMLP-stimulated eosinophil-derived neurotoxin release as well as augment

56 0% inhibition, respectively) IL-5-stimulated eosinophil-derived neurotoxin release in a dose-dependen

57 -CSF also enhanced superoxide production and eosinophil-derived neurotoxin release stimulated by the

58 induced calcium-dependent exocytosis (e.g., eosinophil-derived neurotoxin release) in eosinophils fr

59 increased activation of the Ras-ERK cascade, eosinophil-derived neurotoxin release, and adherence to

60 of eosinophils with IL-5 induced significant eosinophil-derived neurotoxin release.

61 Recombinant eosinophil-derived neurotoxin (rhEDN), the major eosinop